CN1253190C - Medicine for treating diabetes - Google Patents

Medicine for treating diabetes Download PDF

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Publication number
CN1253190C
CN1253190C CN 200410012144 CN200410012144A CN1253190C CN 1253190 C CN1253190 C CN 1253190C CN 200410012144 CN200410012144 CN 200410012144 CN 200410012144 A CN200410012144 A CN 200410012144A CN 1253190 C CN1253190 C CN 1253190C
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radix
medicine
parts
diabetes
root
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CN 200410012144
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CN1557378A (en
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李炳全
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Abstract

The present invention relates to a medicine for curing diabetes by taking Chinese herbal medicines as raw materials, which is prepared from raw materials of the following components: membranous milkvetch root, cornel, common yan rhizome, rehmannia root, ophiopogon root, schisandra fruit, kudzuvine root, trichosanthes, cortex moutan root-bark of tree peony, baical skullcap root, coptis root from Sichuan of China, gypsum, common anemarrhena rhizome, tuckahoe and coix seed. The medicine for curing diabetes is a natural edible plant medicine which can also be taken as diet and has the functions of nourishing yin, invigorating the kidney, replenshing qi deficiency, eliminating turbid pathogens and strengthening vital qi. The medicine for curing diabetes has the prescription according to the theory of traditional Chinese medicine and thereby plays a role of promoting the secretion of endogenous insulins, reducing the peripheral resistance force of exogenous insulins, increasing biological activity, promoting the metabolism of sugar, reducing the decomposition of lipoproteins, lowering blood sugar and blood-fat, improving microcirculation and reducing and relieving the occurrence and the progression of cardiovascular pathological changes for patients with diabetes.

Description

A kind of medicine for the treatment of diabetes
Technical field
The present invention be a kind of be the medicine of the treatment diabetes of feedstock production with the Chinese herbal medicine.
Background technology
Diabetes are common frdquently encountered diseases of serious harm human health.At present, diabetics has surpassed 100,000,000 people in the world, and China is also near 20,000,000, and the trend that increases is year by year arranged.The case fatality rate of diabetes is only second to malignant tumor and cardiovascular diseases, is the third-largest disease that jeopardizes the human life.
Diabetes do not heal all the life, and its complication extensively and seriously, because insulin lacks relatively or definitely in the blood flow, thereby causes sugar, fat, protein metabolism disorder, cause hyperglycemia, hyperlipidemia and haemoconcentration to raise, extensively microangiopathies of the whole body can appear in middle and advanced stage.Wherein cardiovascular diseases, diabetes kidney function failure and cerebrovascular disease are the common causes of death of middle and elderly diabetic patient, and its mortality rate is up to 70%~80%.
At present, the Drug therapy of both at home and abroad primary disease being carried out has run into following thorny problem:
1, the biguanide drug curative effect is low, and side effect is big, for a long time with producing hyperlactacidemia.
2, with damaging liver, kidney and hemocyte, meeting and sulphonamides produce cross allergy to ioduria class medicine for a long time, and the later stage will cause secondary failure.
3, with producing antibody, biological activity reduces insulin for a long time.And dosage increases can produce hyperinsulinemia, impels the generation of microangiopathies.
Summary of the invention
The invention solves the big technical barrier of drug side effect of existing treatment diabetes, and adopt a kind of enriching yin and nourishing kidney, QI invigorating void, disappear turbidly let out, the body resistance strengthening and constitution consolidating, the homologous natural edible plant of medicated diet treat diabetes as medicine.
The present invention adopts following method to realize, its preparation of raw material by following component forms, Radix Astragali 3-5 part Fructus Corni 2-5 part Rhizoma Dioscoreae 2-6 part Radix Rehmanniae 1.5-3 part 2-6 Radix Ophiopogonis part Fructus Schisandrae Chinensis 1.5-3 part Radix Puerariae 2-6 part Radix Trichosanthis 2-6 part Cortex Moutan 1-3 part Radix Scutellariae 1.5-3 part Rhizoma Coptidis 1-3 part Gypsum Fibrosum 1-3 part Rhizoma Anemarrhenae 1-3 part Poria 1.5-3 part Semen Coicis 1-3 part.
The present invention is formed by the preparation of raw material of following component, 1 part of 1.5 parts of Semen Coicis of 2 parts of Radix Rehmanniae of 3 portions of Rhizoma Dioscoreaes of 3 parts of Fructus Corni of the Radix Astragali, 1 part of Poria of 1 part of Rhizoma Anemarrhenae of 1 part of Gypsum Fibrosum of 1.5 parts of Rhizoma Coptidis of 1 part of Radix Scutellariae of 2 parts of Cortex Moutans of 2 parts of Radix Trichosanthis of 1.5 parts of Radix Puerariaes of 2 parts of Fructus Schisandrae Chinensis, 1.5 parts of Radix Ophiopogonis.
The present invention be according to Chinese herbal and crude drugs preparations monarch, minister, help, make and compatibility.The symptom of diabetes performance is many desires, polyphagia, polyuria, tired becoming thin.Desire to cause humidity hysteresis more; Polyphagia produces scorching, achyli; Polyuria body fluid scatters and disappears.In this preparation, the Radix Astragali, Fructus Corni, Rhizoma Dioscoreae QI invigorating void, tonifying kidney-yin, the body resistance strengthening and constitution consolidating; The Radix Rehmanniae, Radix Ophiopogonis, Fructus Schisandrae Chinensis are augmented body fluid; Radix Puerariae, Radix Trichosanthis relieving restlessness are quenched one's thirst; Cortex Moutan, Radix Scutellariae, Rhizoma Coptidis heat clearing away are dry; Gypsum Fibrosum, Rhizoma Anemarrhenae clearing away dryness Bao Weijin; Poria, Semen Coicis eliminating dampness by diuresis resolving depression.
The present invention is based on motherland's medical science to diabetes and pathogenetic understanding of complication and Therapeutic Principle, with reference to the modern pharmacological research achievement, a kind of enriching yin and nourishing kidney that from motherland's medical treasure-house, filter out, QI invigorating void, disappear turbidly let out, the body resistance strengthening and constitution consolidating, the homologous natural edible-plant medicine of medicated diet.It is by the theory of Chinese medical science prescription, played and promoted endogenous secretion of insulin, reduce the peripheral drag of exogenous insulin, increase biological activity, promote the metabolism of sugar, reduce the decomposition of fat protein, lowering blood sugar and blood fat, microcirculation improvement, the effect that reduce, development takes place diabetes-alleviating patient cardiovascular pathological changes.
The process for preparing medicine of treatment diabetes is:
1, gets Fructus Corni drying and crushing to 120 order fine powder by said ratio.
2, with the Radix Rehmanniae, Radix Ophiopogonis-15 ℃ freezing down, dry post-treatment is ground into 120 order fine powders.
3, the Radix Astragali, Fructus Schisandrae Chinensis, Cortex Moutan, Rhizoma Dioscoreae, Radix Puerariae, Radix Trichosanthis, Radix Scutellariae, Rhizoma Coptidis, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Poria, Semen Coicis are ground into 120 order fine powders after air-dry.
4, above-mentioned whole medicated powder are mixed the back and under 100-110 ℃, carry out ripening, sterilization treatment, the powder medicine of the 10-30 minute diabetes that can obtain medical treatment.
The ripening disinfecting action is to adopt step type cooling ripening sterilization, earlier temperature is raised to 110 ℃ rapidly, and segmentation then drops to 100 ℃, and whole process needs 10-30 minute.The I capsule of packing under the sterile working of the powder medicated powder after the maturation process, every heavy≤0.5 gram is promptly made this medicine.
Effect of the present invention and advantage,
The present invention is example through clinical practice with 139 routine cases, and concrete efficacy result statistics is as follows
Cure Take a turn for the better Invalid Add up to Effective percentage %
128 11 139 92.10
More than curing is that to reach 6.6mmol/L with blood glucose be standard, and taking a turn for the better, to reach 6.7mmol/L with blood glucose be standard.
Clinical case 1:
Jiang XX, man, 64 years old.Suffer from diabetes, curative effect of medication such as clothes metformin, nitrendipine are not obvious.Examine August 10 calendar year 2001, the patient is conscious: headache, dizziness, myasthenia of limbs, blurred vision amaurosis, xerostomia, frequent micturition; Observe: face is gloomy, language is overcast, the sweating due to debility sound of wind or of flowing waters; After testing: blood glucose 14.3mmol/L, blood pressure 190/110mmHg, diagnosis belongs to diabetic syndrome.
After take this medicine, day clothes twice, each 4 sooner or later.Take medicine after the course of treatment (three months), conscious disease obviously alleviates, and detects: blood glucose 8.0mmol/L, blood pressure 135/90mmHg; After continuing to take two courses of treatment (six months), subjective symptoms is all removed, and detects: blood glucose 7.1mmol/L, blood pressure 130/90mmHg; After keeping a course of treatment, blood glucose 6.8mmol/L, the state of an illness is clearly better.
Case 2:
Model XX, woman, 60 years old.Obeying insoral, No. 0 medicine such as blood pressure lowering when April 2 examined in 2002.The patient is conscious: xerostomia send out yearningly, urinate time many, health fatigue and weak, vexed hot-tempered; Observe: pale complexion, send out as do fiber crops, become thin; Detect: blood glucose 9.0mmol/L, blood pressure 145/95mmHg, diagnosis belongs to diabetic syndrome.
It withdraws Western medicine immediately the back suggestion, changes this medicine of clothes, day clothes twice, each 4 sooner or later.Take medicine after two courses of treatment (six months), after testing: blood glucose 6.9mmol/L, blood pressure 130/90mmHg; Continue to take medicine after three courses of treatment (nine months), of pink and healthy-looking, the hair blackening, weight increase is progressively got well, and detect: blood glucose 6.6mmol/L, blood pressure 130/90mmHg cures.
Case 3:
King XX, man, 39 years old.On March 8th, 2003 examined.Patient main suit: drink and thirstyly do not understand, food and hungry insatiable hunger, urine is time many, detect: blood glucose 8.0mmol/L, blood pressure 125/90mmHg, diagnosis belongs to the simple type diabetes.
After take this Drug therapy, day clothes twice, each 4 sooner or later.Take medicine after the course of treatment (three months), thirsty, hungry sense alleviates, and urine is normal, detects: blood glucose 6.5mmol/L, blood pressure 130/90mmHg; After keeping the course of treatment (three months) of taking medicine, all indexs are normal, fully recover.
This Chinese patent medicine formula and manufacture method uniqueness, therapeutic effect is remarkable, and effective percentage can reach more than 92%.
The specific embodiment
Take by weighing 1 part of 1.5 parts of Semen Coicis of 2 parts of Radix Rehmanniae of 3 portions of Rhizoma Dioscoreaes of 3 parts of Fructus Corni of the Radix Astragali, 1 part of Poria of 1 part of Rhizoma Anemarrhenae of 1 part of Gypsum Fibrosum of 1.5 parts of Rhizoma Coptidis of 1 part of Radix Scutellariae of 2 parts of Cortex Moutans of 2 parts of Radix Trichosanthis of 1.5 parts of Radix Puerariaes of 2 parts of Fructus Schisandrae Chinensis, 1.5 parts of Radix Ophiopogonis, every part with 1 gram calculating.
1, gets Fructus Corni drying and crushing to 120 order fine powder by said ratio.
2, with the Radix Rehmanniae, Radix Ophiopogonis-15 ℃ freezing down, dry post-treatment is ground into 120 order fine powders.
3, the Radix Astragali, Fructus Schisandrae Chinensis, Cortex Moutan, Rhizoma Dioscoreae, Radix Puerariae, Radix Trichosanthis, Radix Scutellariae, Rhizoma Coptidis, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Poria, Semen Coicis are ground into 120 order fine powders after air-dry.
4, above-mentioned whole medicated powder are mixed the back and under 100-110 ℃, carry out ripening, sterilization treatment, the powder medicine of the 10-30 minute diabetes that can obtain medical treatment.
The ripening disinfecting action is to adopt step type cooling ripening sterilization, earlier temperature is raised to 110 ℃ rapidly, and segmentation then drops to 100 ℃, and whole process needs 10-30 minute.The I capsule of packing under the sterile working of the powder medicated powder after the maturation process, every heavy≤0.5 gram is promptly made this medicine.

Claims (3)

1, a kind of medicine for the treatment of diabetes is formed by the preparation of raw material of following component,
Radix Astragali 3-5 part Fructus Corni 2-5 part Rhizoma Dioscoreae 2-6 part Radix Rehmanniae 1.5-3 part
Radix Ophiopogonis 2-6 part Fructus Schisandrae Chinensis 1.5-3 part Radix Puerariae 2-6 part Radix Trichosanthis 2-6 part
Cortex Moutan 1-3 part Radix Scutellariae 1.5-3 part Rhizoma Coptidis 1-3 part Gypsum Fibrosum 1-3 part
Rhizoma Anemarrhenae 1-3 part Poria 1.5-3 part Semen Coicis 1-3 part.
2, a kind of medicine for the treatment of diabetes is formed by the preparation of raw material of following component,
1.5 parts in 2 parts of Radix Rehmanniae of 3 portions of Rhizoma Dioscoreaes of 3 parts of Fructus Corni of the Radix Astragali
2 parts of 2 parts of Radix Trichosanthis of 1.5 parts of Radix Puerariaes of 2 parts of Fructus Schisandrae Chinensis Radix Ophiopogonis
1 part in 1 part of Gypsum Fibrosum of 1.5 parts of Rhizoma Coptidis of 1 part of Radix Scutellariae of Cortex Moutan
1 part of 1.5 parts of Semen Coicis of 1 part of Poria of the Rhizoma Anemarrhenae.
3, the described method of preparation claim 1 is characterized in that:
(1), get Fructus Corni drying and crushing to 120 order fine powder, by said ratio
(2), with the Radix Rehmanniae, Radix Ophiopogonis-15 ℃ freezing down, dry post-treatment is ground into 120 order fine powders,
(3), the Radix Astragali, Fructus Schisandrae Chinensis, Cortex Moutan, Rhizoma Dioscoreae, Radix Puerariae, Radix Trichosanthis, Radix Scutellariae, Rhizoma Coptidis, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Poria, Semen Coicis are ground into 120 order fine powders after air-dry,
(4), above-mentioned whole medicated powder are mixed the back and under 100-110 ℃, carry out ripening, sterilization treatment, the powder medicine of the 10-30 minute diabetes that can obtain medical treatment.
CN 200410012144 2004-02-07 2004-02-07 Medicine for treating diabetes Expired - Fee Related CN1253190C (en)

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CN1253190C true CN1253190C (en) 2006-04-26

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1310668C (en) * 2005-07-15 2007-04-18 中国人民解放军第三军医大学第二附属医院 Medicine for treating diabetes, and its prepn. method
CN101601794B (en) * 2008-06-13 2011-01-26 任淑君 Traditional Chinese medicine preparation for reducing glucose and removing thirst
CN101406618B (en) * 2008-11-21 2011-08-24 汝州市中医院 Traditional Chinese medicine mixture for treating diabetes
CN101947296A (en) * 2010-09-04 2011-01-19 王福山 Chinese medicine composition for treating diabetes
CN104095233A (en) * 2014-06-27 2014-10-15 桂林浩新科技服务有限公司 Medicated diet for treating diabetes
CN104524359B (en) * 2014-12-31 2017-08-25 吉林省德商药业有限公司 A kind of Chinese medicine composition, its preparation method and application

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