CN1211434A - Oral liquid for resisting altitude stress and its preparation method - Google Patents

Abstract

An oral liquid for treating acute or chronic altitude reaction is prepared from 25 Chinese-medicinal materials such as ginseng, rhodiola root, Dictyophora phalloidea, liquorice root, Chinese angelica root, etc.It can also increase immunity and resistance to sanility and fatigue, and invigorate the function of brain.

Description

A kind of oral liquid for resisting altitude stress and preparation method thereof

The present invention relates to a kind of oral liquid for resisting altitude stress and preparation method thereof.

Altitude sickness is divided into acute high altitude reaction and tardy property altitude sickness.

The traditional Chinese medical science is thought: acute high altitude reaction is after people's speed is entered the plateau, body is to factor incompatibilities such as hypoxic plateau environment, low pressure, high and cold, dry, intensive ultraviolets, water humidity hysteresis stream in the body, the stress that infects clouds and mists in the mountains pathogenic heat miasma and take place, it is mainly with systematic influence maximums such as nerve, breathing, cardiovascular, digestion, its clinical manifestation for headache, dizzy, irritated, have a sleepless night, do not get into bed, cardiopalmus, breathe hard, uncomfortable in chest, cough, weak, edema, poor appetite, nausea,vomiting,diarrhea, epistaxis, pulmonary edema, altitude coma etc. can appear in severe depletion of oxygen person.Tardy property altitude sickness mainly refers to owing to occupy the plateau for a long time, the body chronic hypoxia, causing erythrocyte increases excessively and the comprehensive syndrome that occurs, erythrocyte, hemoglobin increase, packed cell volume significantly increases, organs and tissues hyperemia, stasis of blood stream and anoxia infringement, clinical manifestation be neurasthenia symptom, headache, dizziness, insomnia, hypomnesis, absent minded, tired, cardiopalmus, breathe hard, be off one's feed, dyspepsia, numb hand and foot, puffiness of face, sometimes arrhythmia, premature beat, paroxysmal tachycardia or transience dizziness etc. can be arranged.The medicine of present anti-acute and chronic altitude sickness mainly contains Rhodiola root oral liquid etc., the health product of also using buttered tea as altitude sickness prevention among the people, inclined to one side face is a theoretical foundation to replenish vigour but above-mentioned medicine or health product are mostly with high altitude anoxia, effect is also unsatisfactory, buttered tea is also higher owing to containing fat in addition, and long-term drink can cause fatty liver, cholecystitis, obesity, hyperlipidemia etc.

Modern medicine thinks that altitude sickness is owing to stress and the compensation of body in altitude environment, the high originality syndrome time group that heart beating accelerated breathing, hypertension, leukocyte raise, digestion is simultaneously secreted less, gastrointestinal peristalsis is limited, total body water is received pool stream, the intercellular substance edema is caused.The modern medicine treatment is gone up does not just have other processing method except that oxygen supply, anti symptom treatment.

The purpose of this invention is to provide and a kind ofly can effectively resist oral liquid of altitude sickness and preparation method thereof, but this oral liquid also human body immunity improving ability, defying age, anti-tired out, brain-strengthening etc.

The object of the present invention is achieved like this.A kind of oral liquid for resisting altitude stress is characterized in that: it is (in the parts by weight) that the raw material by following prescription is made,

Radix Ginseng 10-30 part Radix Rhodiolae 15-30 part

Caulis Bambusae In Taeniam 15-30 part Radix Glycyrrhizae 3-10 part

Radix Angelicae Sinensis 5-15 part Radix Rehmanniae Preparata 10-25 part

Fructus Lycii 6-12 part 10-15 Radix Ophiopogonis part

Fructus Ligustri Lucidi 10-15 part Cordyceps 6-12 part

Cortex Eucommiae 10-15 part Herba arenariae kansuensis 5-15 part

Poria 10-15 part Talcum 10-30 part

Cortex Magnoliae Officinalis 10-15 part Fructus Amomi Rotundus 8-12 part

Rhizoma Pinelliae 8-12 part Rhizoma Chuanxiong 10-15 part

Radix Notoginseng 5-10 part Flos Carthami 5-10 part

Radix Salviae Miltiorrhizae 10-15 part Fructus Gardeniae 10-15 part

Semen Armeniacae Amarum 8-12 part Semen Ziziphi Spinosae 10-15 part

Caulis Polygoni Multiflori 10-20 part crystal sugar 25-30 part

Radix Ginseng, Radix Rhodiolae, Radix Glycyrrhizae are to replenish vigour in this prescription.Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Fructus Lycii play the effect that tonification is nourished blood.Cordyceps, Caulis Bambusae In Taeniam, Herba arenariae kansuensis, the Cortex Eucommiae, Radix Ophiopogonis, Fructus Ligustri Lucidi have human body immunity improving power, regulate equilibrium between yin and yang, replenishing and restoring lung-QI, the effect of nourishing the liver and kidney.Poria, Talcum have the merit of inducing diuresis and reducing edema dehydration, spleen invigorating mind calming.Radix Notoginseng, Radix Salviae Miltiorrhizae, Flos Carthami, Cortex Magnoliae Officinalis, Rhizoma Chuanxiong are activating blood circulation to dissipate blood stasis, inducing menstruation to relieve menalgia, the relieving restlessness that clears away heart-fire is regulated the flow of vital energy.The painful abdominal mass but Fructus Amomi Rotundus, Rhizoma Pinelliae drying dampness to eliminate phlegm, sending down the abnormal ascending QI emesis, removing food stagnancy loose.But the Fructus Gardeniae removing pathogenic heat from blood and toxic substance from the body, unload fiery relieving restlessness.But Semen Armeniacae Amarum, Semen Ziziphi Spinosae, Caulis Polygoni Multiflori tranquilizing by nourishing the heart, relieving cough and asthma, dispelling wind and removing obstruction in the collateral.Crystal sugar had both played the effect of stomach function regulating, also played the effect of regulating taste.

The preparation method of this medicine is:

One, raw material processing, the process of preparing Chinese medicine

Choose raw material except that crystal sugar, Radix Rhodiolae by prescription, clean oven dry, section pulverizes that to form coarse fodder standby then.Radix Rhodiolae will be concocted, and its concocting method is: Radix Rhodiolae is cleaned the back section, do down at 80-100 ℃ and fry, make it to become orange-yellow, it is standby after 15-20 minute to fry in shallow oil stir-fry again by the ratio adding butter of Radix Rhodiolae and butter 1/1-2 (g/g) then.

Two, soak with ethanol Extracting juice

The raw material that step 1 processing is cooked is with 50 °-60 ° soaking in Chinese liquor, and the ratio of raw material and Chinese liquor is 1/3-5 (g/ml), and it is standby to soak after 15-20 days centrifugal overanxious formation mother solution.

Three, medicinal residues decoct filtration

The medicinal residues that step 2 is obtained decoct with water 3-4 time, decoct 1-2 hour at every turn, and medicinal residues are 1/3-5 (g/ml) with the ratio of each amount of water, filter and extract medicinal liquid

Four, medicinal liquid concentrates and makes product

Mother liquid obtained and the step 3 gained extracting solution mixing with step 2, and press formula ratio and add after the crystal sugar at 60-80 ℃ of concentrated 2.5-3 hour, under 70-80 ℃ of temperature, further concentrate 1.5-2 hour then, add the antiseptic sodium benzoate that accounts for overall concentrated solution 0.2-0.3% (volume ratio) again, at last with bottling behind the infrared ray filtrator sterilised filtration.

The present invention is in conjunction with Chinese and western medicine theory, opinion acute on the plateau and chronic reaction is controlled the geography and climate according to the plateau, environment, atmospheric pressure, temperature, symptom and opinion that ultraviolet radiation etc. develop the physiological change of human body body and pathology and occurred are controlled, to replenish vigour, promote blood flow rate, human body immunity improving power is resisted outer driving, heat-clearing and toxic substances removing, food stagnation removing dampness removing, dehydration, reduce the generation of intercellular substance edema, activating blood circulation to dissipate blood stasis, removing obstruction in the collateral to relieve pain, mind tranquilizing and the heart calming, prevent that cerebral from raising, short blood flow circulation improves the blood circulation of heart stolen goods, thereby reaches the purpose of health therapy.This medicine is except that the effect with opposing altitude sickness, but also human body immunity improving ability, defying age, anti-tired out, brain-strengthening etc.This medicine not only adopts the Chinese medicine processing technique on method for making, also extract in conjunction with modern technologies, and effective ingredient in the medicine is made full use of.

Medicine of the present invention clinical trial, testee 120 examples, the group of taking medicine 70 examples, matched group 50 examples, wherein:

Male 46 examples of the group of taking medicine, women 24 examples, the age is 15 examples below 20 years old, 20-29 year 14 examples, 30-39 year 26 examples, 40-49 year 15 examples, 10 examples more than 50 years old, this group are promptly taken medicine after entering the highlands, produce effects 18 examples account for 25.7%.Effective 40 examples account for 57.1%, and are invalid 15.7%, increase the weight of 1 example, account for 1.4%, total effective rate 82.8%, inefficiency 17.1%;

Matched group man 27 examples, women 23 examples, age 20-30 year 16 examples, 30-39 year 20 examples, 40-49 year 9 examples, 5 examples more than 50 years old, this group personnel go by air after speed enters the plateau, and follow-up examination within 7 days alleviates 2 examples, account for 4%, no change 8 examples account for 16%, increase the weight of 40 examples, account for 80%, always alleviate rate 4%, inefficiency 96%.

Embodiment one:

A kind of oral liquid for resisting altitude stress is characterized in that: it is (in the parts by weight) that the feedstock production by following prescription forms,

30 parts of 20 parts of Radix Rhodiolaes of Radix Ginseng

6 parts in 20 portions of Radix Glycyrrhizaes of Caulis Bambusae In Taeniam

15 parts in 15 parts of Radix Rehmanniaes Preparata of Radix Angelicae Sinensis

15 parts of Fructus Lycii 12 parts of Radix Ophiopogonis

10 parts of 15 portions of Cordycepses of Fructus Ligustri Lucidi

15 parts of 15 parts of Herba arenariae kansuensis of the Cortex Eucommiae

15 parts in 15 parts of Talcums of Poria

12 parts of 12 parts of Fructus Amomi Rotundus of Cortex Magnoliae Officinalis

12 parts of 12 parts of Rhizoma Chuanxiongs of the Rhizoma Pinelliae

10 parts on 6 parts of Flos Carthamis of Radix Notoginseng

15 parts of 15 parts of Fructus Gardeniae of Radix Salviae Miltiorrhizae

15 parts of 10 parts of Semen Ziziphi Spinosaes of Semen Armeniacae Amarum

30 parts in 12 portions of crystal sugar of Caulis Polygoni Multiflori

This oral liquid can make with following method:

One, raw material processing, the process of preparing Chinese medicine

Choose raw material except that crystal sugar, Radix Rhodiolae by prescription, clean oven dry, section pulverizes that to form coarse fodder standby then.Radix Rhodiolae will be concocted, and its concocting method is: Radix Rhodiolae is cleaned the back section, do down at 90 ℃ and fry, make it to become orange-yellow, it is standby after 18 minutes to fry in shallow oil stir-fry again by the ratio adding butter of Radix Rhodiolae and butter 1/1.5 (g/g) then.

Two, soak with ethanol Extracting juice

The raw material that step 1 processing is cooked is with 55 ° soaking in Chinese liquor, and the ratio of raw material and Chinese liquor is 1/4 (g/ml), and it is standby to soak after 18 days centrifugal overanxious formation mother solution.

Three, medicinal residues decoct filtration

The medicinal residues that step 2 is obtained decoct with water 4 times, decoct 2 hours at every turn, and medicinal residues are 1/4 (g/ml) with the ratio of each amount of water, filter and extract medicinal liquid

Four, medicinal liquid concentrates and makes product

Mother liquid obtained and the step 3 gained extracting solution mixing with step 2, and concentrate 3 hours at 60 ℃ after pressing formula ratio adding crystal sugar, under 80 ℃ of temperature, further concentrate 2 hours then, add the antiseptic sodium benzoate that accounts for overall concentrated solution 0.3% (volume ratio) again, at last with bottling behind the infrared ray filtrator sterilised filtration.

Claims (2)

1, a kind of oral liquid for resisting altitude stress is characterized in that: it is (in the parts by weight) that the raw material by following prescription is made,

Radix Ginseng 10-30 part Radix Rhodiolae 15-30 part

Caulis Bambusae In Taeniam 15-30 part Radix Glycyrrhizae 3-10 part

Radix Angelicae Sinensis 5-15 part Radix Rehmanniae Preparata 10-25 part

Fructus Lycii 6-12 part 10-15 Radix Ophiopogonis part

Fructus Ligustri Lucidi 10-15 part Cordyceps 6-12 part

Cortex Eucommiae 10-15 part Herba arenariae kansuensis 5-15 part

Poria 10-15 part Talcum 10-30 part

Cortex Magnoliae Officinalis 10-15 part Fructus Amomi Rotundus 8-12 part

Rhizoma Pinelliae 8-12 part Rhizoma Chuanxiong 10-15 part

Radix Notoginseng 5-10 part Flos Carthami 5-10 part

Radix Salviae Miltiorrhizae 10-15 part Fructus Gardeniae 10-15 part

Semen Armeniacae Amarum 8-12 part Semen Ziziphi Spinosae 10-15 part

Caulis Polygoni Multiflori 10-20 part crystal sugar 25-30 part

2, a kind of method for preparing the described oral liquid for resisting altitude stress of claim 1, it is characterized in that: it may further comprise the steps

One, raw material processing, the process of preparing Chinese medicine

Choose raw material except that crystal sugar, Radix Rhodiolae by prescription, clean oven dry, section pulverizes that to form coarse fodder standby then.Radix Rhodiolae will be concocted, and its concocting method is: Radix Rhodiolae is cleaned the back section, do down at 80-100 ℃ and fry, make it to become orange-yellow, it is standby after 15-20 minute to fry in shallow oil stir-fry again by the ratio adding butter of Radix Rhodiolae and butter 1/1-2 (g/g) then.

Two, soak with ethanol Extracting juice

The raw material that step 1 processing is cooked is with 50-60 ℃ soaking in Chinese liquor, and the ratio of raw material and Chinese liquor is 1/3-5 (g/ml), and it is standby to soak after 15-20 days centrifugal overanxious formation mother solution.

Three, medicinal residues decoct filtration

The medicinal residues that step 2 is obtained decoct with water 3-4 time, decoct 1-2 hour at every turn, and medicinal residues are 1/3-5 (g/ml) with the ratio of each amount of water, filter and extract medicinal liquid

Four, medicinal liquid concentrates and makes product

Mother liquid obtained and the step 3 gained extracting solution mixing with step 2, and press formula ratio and add after the crystal sugar at 60-80 ℃ of concentrated 2.5-3 hour, under 70-80 ℃ of temperature, further concentrate 1.5-2 hour then, add the antiseptic sodium benzoate that accounts for overall concentrated solution 0.2-0.3% (volume ratio) again, at last with bottling behind the infrared ray filtrator sterilised filtration.