CN101249255B - Proprietary Chinese medicine for curing children's cough and method of preparing the same - Google Patents
Proprietary Chinese medicine for curing children's cough and method of preparing the same Download PDFInfo
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- CN101249255B CN101249255B CN2008100695310A CN200810069531A CN101249255B CN 101249255 B CN101249255 B CN 101249255B CN 2008100695310 A CN2008100695310 A CN 2008100695310A CN 200810069531 A CN200810069531 A CN 200810069531A CN 101249255 B CN101249255 B CN 101249255B
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Abstract
The invention provides a Chinese patent medicine which is used to cure children cough. The invention is characterized in that the Chinese patent medicine is a medicament prepared by the raw materials by the weight ratios as follows: ginseng 18 to 22, poria cocos 18 to 22, atractylodes 7 to 9, tangerine peel 18 to 22, chicken's gizzard-skin 18 to 22, rhubarb 10 to 14, turtle shell 18 to 22, wofberry bark 22 to 24, radix glehniae 38 to 40, glycyrrhiza 10 to 14, southernwood 28 to 30, radix ophiopogonis 38 to 40, cassia twig 7 to 9, dried ginger 7 to 9, radix psuedostellariae 18 to 22, snakegourd fruit 28 to 30, coltsfoot flower 18 to 22, tatarian aster root 18 to 22, white mulberry root-bark 22 to 24, arisaema cum bile 7 to 9, astragalus root 18 to 22 and barbary wolfberry fruit 18 to 22. With littlie toxic and side effects and good efficacy, the inventive Chinese patent medicine is applicable for children.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of infantile cough and preparation method thereof.
Background technology
The Chinese patent medicine of treatment infantile cough uses more having " children's's pulmonary cough granule " at present, but the Radix Aconiti Lateralis Preparata in this medicine composition is big hot medical material and has certain toxicity, during the clinical trial, through clinical symptoms, the result that sign and safety indexes are observed, this medicine is for the careful usefulness of high heat cough person, and wind-heat invading lung type cough should not use, and is unfavorable for that more children's uses.In addition, among the preparation technology of this medicine, what the employing of part material medical material was arranged is to pulverize to be used as medicine, and effective ingredient is difficult to stripping and absorption, directly influences the curative effect of this medicine.
Summary of the invention
Purpose of the present invention just is to provide a kind of Chinese patent medicine for the treatment of infantile cough, and this Chinese patent medicine toxic and side effects is little, good effect and be suitable for children's to use.
Another object of the present invention provides the preparation method of this Chinese patent medicine.
The object of the present invention is achieved like this: a kind of Chinese patent medicine for the treatment of infantile cough is characterized in that it is the medicament of being made by the following weight parts proportion raw material: Radix Ginseng 18～22, Poria 18～22, the Rhizoma Atractylodis Macrocephalae 7～9, Pericarpium Citri Reticulatae 18～22, Endothelium Corneum Gigeriae Galli 18～22, Radix Et Rhizoma Rhei 10～14, Carapax Trionycis 18～22, Cortex Lycii 22～24, Radix Glehniae 38～40, Radix Glycyrrhizae 10～14, Herba Artemisiae Annuae 28～30, Radix Ophiopogonis 38～40, Ramulus Cinnamomi 7～9, Rhizoma Zingiberis 7～9, Radix Pseudostellariae 18～22, Fructus Trichosanthis 28～30, Flos Farfarae 18～22, Radix Asteris 18～22, Cortex Mori 22～24, Arisaema Cum Bile 7～9, the Radix Astragali 18～22 and Fructus Lycii 18～22.
The Chinese patent medicine of above-mentioned treatment infantile cough, wherein the weight portion proportion optimization of each raw material is: Radix Ginseng 19, Poria 19, the Rhizoma Atractylodis Macrocephalae 7, Pericarpium Citri Reticulatae 19, Endothelium Corneum Gigeriae Galli 19, Radix Et Rhizoma Rhei 11, Carapax Trionycis 19, Cortex Lycii 22, Radix Glehniae 38, Radix Glycyrrhizae 12, Herba Artemisiae Annuae 28, Radix Ophiopogonis 38, Ramulus Cinnamomi 7, Rhizoma Zingiberis 7, Radix Pseudostellariae 20, Fructus Trichosanthis 28, Flos Farfarae 19, Radix Asteris 19, Cortex Mori 22, Arisaema Cum Bile 7, the Radix Astragali 19 and Fructus Lycii 19.
The Chinese patent medicine of above-mentioned treatment infantile cough, wherein the weight portion proportioning of each raw material can also be preferably: Radix Ginseng 22, Poria 22, the Rhizoma Atractylodis Macrocephalae 9, Pericarpium Citri Reticulatae 22, Endothelium Corneum Gigeriae Galli 22, Radix Et Rhizoma Rhei 13, Carapax Trionycis 22, Cortex Lycii 24, Radix Glehniae 40, Radix Glycyrrhizae 13, Herba Artemisiae Annuae 30, Radix Ophiopogonis 40, Ramulus Cinnamomi 9, Rhizoma Zingiberis 9, Radix Pseudostellariae 22, Fructus Trichosanthis 30, Flos Farfarae 22, Radix Asteris 22, Cortex Mori 24, Arisaema Cum Bile 9, the Radix Astragali 22 and Fructus Lycii 22.
Above-mentioned Radix Et Rhizoma Rhei is a Radix et Rhizoma Rhei (processed with wine); Above-mentioned Radix Glycyrrhizae is a Radix Glycyrrhizae (processed with honey).
The Chinese formulated products of above-mentioned treatment infantile cough is granule or oral liquid or syrup.
The preparation method of the Chinese patent medicine of above-mentioned treatment infantile cough, it may further comprise the steps: said components is decocted with water twice by said ratio, each 2 hours, merge decoction liquor and filter, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, the concentration of adding and this clear paste equivalent is 95% ethanol, left standstill after the stirring 24 hours, and got supernatant and reclaim ethanol, and then further to be condensed into 50 ℃ of following relative densities be 1.30～1.32 extractum, add sucrose, make granule.
Perhaps, said components is decocted with water twice by said ratio, each 2 hours, merge decoction liquor and filter, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, adds concentration with this clear paste equivalent and be 95% ethanol, left standstill after the stirring 24 hours, remove supernatant and reclaim ethanol, and then add suitable quantity of water, make oral liquid after filtration and the sterilization.
Again or, said components is decocted with water twice by said ratio, each 2 hours, merge decoction liquor and filtration, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, adds concentration with this clear paste equivalent and be 95% ethanol, leaves standstill after the stirring 24 hours, remove supernatant and also reclaim ethanol, and then add and make syrup after syrup makes sugar content reach 45%.
The invention has the beneficial effects as follows:
(1) formula for a product of the present invention is rigorous, and monarch is clearly demarcated.Radix Ginseng, Radix Adenophorae (Radix Glehniae), Radix Pseudostellariae are monarch drug in the side, strongly invigorating primordial QI, and the warming the spleen lung benefiting, promoting the production of body fluid and inducing sedation of the mind has strengthening vital QI to eliminate pathogenic factors, enhancing human body immunity power effect; The Radix Astragali, is ministerial drug, the wherein Radix Astragali at the Rhizoma Atractylodis Macrocephalae, Poria, Carapax Trionycis, Radix Ophiopogonis, Fructus Lycii, Fructus Trichosanthis, Flos Farfarae, Radix Asteris, Arisaema Cum Bile, Cortex Mori, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Poria, spleen invigorating lung benefiting are with the ginseng invigorating the spleen to benefit the lung of helping others, the moon of Radix Ophiopogonis, Carapax Trionycis, Fructus Lycii, nourishing lung and kidney, to help the congenital foundation, assist Radix Adenophorae (Radix Glehniae) YIN nourishing and the production of body fluid promoting, above Six-element medicine is assisted monarch drug, strengthening vital QI to eliminate pathogenic factors, with Fructus Trichosanthis, Arisaema Cum Bile, Cortex Mori, preventing phlegm from forming and stopping coughing, eliminating pathogen from the lung for relieving asthma, be ministerial drug altogether; Radix Et Rhizoma Rhei, Herba Artemisiae Annuae, Cortex Lycii, Endothelium Corneum Gigeriae Galli, Rhizoma Zingiberis, Ramulus Cinnamomi, be adjuvant drug, the Radix Et Rhizoma Rhei of processing with wine is with blood circulation promoting and blood stasis dispelling, and Herba Artemisiae Annuae, Cortex Lycii be with clearind deficient heat, and Endothelium Corneum Gigeriae Galli is with digestion-promoting spleen-invigorating, appetite strengthening, and Rhizoma Zingiberis, Ramulus Cinnamomi are with the sun of warming the spleen kidney, reinforcing body resistance; With the Radix Glycyrrhizae is messenger drug, invigorating the spleen and benefiting QI, preventing phlegm from forming and stopping coughing, but and coordinating the actions of various ingredients in a prescription also.In a word, all medicines of monarch are harmonious among the present invention, with the method for " building up the spleen to supplement the lung ", " reinforcing the mother-organ for treating deficiency of the son-organ ", spleen invigorating, lung benefiting, cough-relieving, reduce phlegm.The real good medicine for the treatment infantile cough of product of the present invention, especially to outbreak repeatedly, the difficult hypofunction of both the spleen and lung cough of healing of delay has special effect.Western medicine diagnose children's delay property, bronchopneumonia, infantile bronchitis, flu are seen the above-mentioned symptom person all can be used, and be evident in efficacy.
(2) be the clinical trial responsible department according to " new Chinese medicine clinical trial guideline " by Children's Hospital Attached to Chongqing Medical Univ., Hospital Affiliated To Chengdu Traditional Chinese Medicine Univ, Three Gorges, Chongqing City hospital are that the clinical trial that cooperation unit finishes shows, product treatment children's lung spleen deficiency of the present invention, cough caused or the thick Huang of abundant expectoration of harmony in the phlegm-damp, infantile bronchitiss etc. are seen above patient, cure 197 examples, produce effects 165 examples, improve 27 examples, total effective rate 94.6%; The relevant clinical test data sees Table 1, table 2.Clinical trial show product of the present invention violate for children's's hypofunction of both the spleen and lung cough, wind and cold cough, the wind heat criminal coughs, organizing pneumonia, significant curative effect is arranged, during the clinical trial, through clinical symptoms, sign and safety indexes are observed and are found no bad clinical response and toxic and side effects.
Table 1: relevant clinical test data
| By the sex branch | Proportion | The age-based branch | Proportion |
| Male's 237 examples | 57.7％ | 135 examples below 1 year old | 32.8％ |
| Women's 174 examples | 42.3％ | 1～3 year old 187 example | 45.5％ |
| 3～6 years old 69 examples | 16.8％ | ||
| 6～9 years old 10 examples | 2.4％ | ||
| 10 examples more than 9 years old | 2.4％ |
Add up to case 411 examples in the table 1, wherein course of disease weak point person is 30, elder 90 days, and average 45 days, all case all had clothes Chinese medicine and western medicine history.
Clinical manifestation: in 411 examples of coughing, with asthma person's 242 examples, with heating person's 70 examples, with flushing person's 54 examples, with red tongue person 54 examples, with unable person's 89 examples of deficient and rapid pulse, occupy FENGGUAN person's 322 examples with the fingerprint yellow skin.
Clinical diagnosis: 242 routine organizing pneumonias are arranged: auscultation of lung all has coarse rales, and wherein lung X-ray radiological survey X 183 examples except that the minority lung marking has the enhancing slightly, there is no unusual; 169 routine chronic bronchitiss are arranged.
Add up as table 2 by clinical test results after taking product of the present invention.Wherein the dose of product of the present invention is: be equivalent to crude drug 0.876g below one-year-old at every turn; Be equivalent to crude drug 1.314g in one to four years old at every turn; Be equivalent to crude drug 2.628 in five to eight years old at every turn; 3 times on the one.The mode of taking is oral.
Table 2: product clinical trial therapeutic outcome of the present invention
(3) Chinese patent medicine of treatment infantile cough has relatively been discarded the Radix Aconiti Lateralis Preparata in the raw material in prescription of the present invention and the prior art; Because of Radix Aconiti Lateralis Preparata is big hot medical material and has certain toxicity, the careful usefulness of high heat cough person is unfavorable for that more children's uses, thereby so the present invention reduced its toxic and side effects by discarded Radix Aconiti Lateralis Preparata and make it be suitable for children's to use; And added Radix Pseudostellariae in the present invention's prescription, Radix Pseudostellariae belongs to the dried root of pinkwort Radix Ginseng, sweet in the mouth, little hardship, the merit of tool replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung, be useful for insufficiency of the spleen weak, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, diseases such as dryness of the lung dry cough, after chronic cough in children, the magical effect of play strong its spleen, Sheng Qijin, moistening its lung.
(4) product of the present invention is applicable to: 1. hypofunction of both the spleen and lung cough; Clinical manifestation: cough is breathed hard, and low voice is weak, and is tired, the spontaneous perspiration poor appetite, and breast gastral cavity painful abdominal mass is vexed, and big loose stool is thin, then cough and asthma outbreak or increase the weight of of wind and cold whenever, tongue is thin in vain, and arteries and veins is faint-hearted slow, generally outbreak repeatedly, delay is difficult.2. the wind and cold criminal coughs; Clinical manifestation: onset is more anxious, cough, and expectorant is rare clearly in vain, snivel, nasal obstruction sneeze, the headache general pain, the slight fever of being afraid of cold, lossless, mouth is not thirsty, and diet reduces, thin white fur of tongue, floating and tense pulse.3. the wind heat criminal coughs; Clinical manifestation: the stream turbid nasal discharge, yellow sticky expectorant is told in cough, with fever and sweating, the dry pharynx sufferings, thirst and liking drink, big dry stool, yellow urine, the tonsil redness, pharyngeal congestion, tongue fur BOHUANG or yellow thick, tongue fur is red, floating pulse and fast.And contain big hot medical material Radix Aconiti Lateralis Preparata in the Chinese patent medicine of treatment infantile cough in the prior art, be not suitable for the wind heat criminal and cough.4. delay property cough; Clinical manifestation: the chronic persistent cough that various diseases causes, chronic for a long time, the repeatability cough has or does not have expectorant.
(5) changed the method for making of in the former technology the direct pulverizing of raw medicinal material being used as medicine in the preparation method of product of the present invention, because this method for making, the effective ingredient of raw medicinal material is difficult to obtain stripping and absorption in human body; But a big chunk of coming out through the medicinal material extract of extracting belongs to invalid components, such as saccharide, tannin, protein etc., causes current Chinese patent medicine ubiquitous " thick, big, black " phenomenon.Be that whole medical materials are passed through to extract in the preparation method of product of the present invention, then extracting solution is removed invalid components through ethanol precipitation, thereby has improved the curative effect of product of the present invention effectively.
The specific embodiment
Mode below by embodiment further specifies the present invention, does not therefore limit the present invention among the described scope of embodiments.
Embodiment 1: a kind of granule for the treatment of infantile cough, wherein the weight portion proportioning of each raw material is: Radix Ginseng 19, Poria 19, the Rhizoma Atractylodis Macrocephalae 7, Pericarpium Citri Reticulatae 19, Endothelium Corneum Gigeriae Galli 19, Radix Et Rhizoma Rhei 11, Carapax Trionycis 19, Cortex Lycii 22, Radix Glehniae 38, Radix Glycyrrhizae 12, Herba Artemisiae Annuae 28, Radix Ophiopogonis 38, Ramulus Cinnamomi 7, Rhizoma Zingiberis 7, Radix Pseudostellariae 20, Fructus Trichosanthis 28, Flos Farfarae 19, Radix Asteris 19, Cortex Mori 22, Arisaema Cum Bile 7, the Radix Astragali 19 and Fructus Lycii 19.
Above-mentioned Radix Et Rhizoma Rhei is a Radix et Rhizoma Rhei (processed with wine), is about to the sheet that rhubarb medicinal material cuts into 2～4mm earlier, and the yellow wine of the material amount 10% of getting it filled is mixed thoroughly with it, after moistening to wine is exhausted, puts in the pot and fries to buff with slow fire, takes out, cool the getting final product of drying in the air.
Above-mentioned Radix Glycyrrhizae is a Radix Glycyrrhizae (processed with honey), and promptly the extracting liquorice medical material cuts into the sheet of 2～4mm earlier, and the refined honey of the material amount 25% of getting it filled is mixed thoroughly with it, and is vexed, puts when frying to buff with slow fire in the medicine cookeding pot, takes out, cool the getting final product of drying in the air.
The preparation method of above-mentioned granule: said components is decocted with water twice by said ratio, each 2 hours, merge decoction liquor and filtration, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, adds concentration with this clear paste equivalent and be 95% ethanol, leaves standstill after the stirring 24 hours, remove supernatant and reclaim ethanol, and then further to be condensed into 50 ℃ of following relative densities be 1.30～1.32 extractum, adds sucrose, makes granule.
Embodiment 2: a kind of oral liquid for the treatment of infantile cough, wherein the weight portion proportioning of each raw material is: Radix Ginseng 22, Poria 22, the Rhizoma Atractylodis Macrocephalae 9, Pericarpium Citri Reticulatae 22, Endothelium Corneum Gigeriae Galli 22, Radix Et Rhizoma Rhei 13, Carapax Trionycis 22, Cortex Lycii 24, Radix Glehniae 40, Radix Glycyrrhizae 13, Herba Artemisiae Annuae 30, Radix Ophiopogonis 40, Ramulus Cinnamomi 9, Rhizoma Zingiberis 9, Radix Pseudostellariae 22, Fructus Trichosanthis 30, Flos Farfarae 22, Radix Asteris 22, Cortex Mori 24, Arisaema Cum Bile 9, the Radix Astragali 22 and Fructus Lycii 22.
Wherein: above-mentioned Radix Et Rhizoma Rhei is a Radix et Rhizoma Rhei (processed with wine) with embodiment 1; Above-mentioned Radix Glycyrrhizae is a Radix Glycyrrhizae (processed with honey) with embodiment 1.
The preparation method of above-mentioned oral liquid: said components is decocted with water twice by said ratio, each 2 hours, merge decoction liquor and filtration, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, the concentration of adding and this clear paste equivalent is 95% ethanol, leaves standstill after the stirring 24 hours, removes supernatant and also reclaims ethanol, and then the adding suitable quantity of water, make oral liquid after filtration and the sterilization.
Embodiment 3: a kind of syrup for the treatment of infantile cough, wherein the weight portion proportioning of each raw material is: Radix Ginseng 18, Poria 18, the Rhizoma Atractylodis Macrocephalae 8, Pericarpium Citri Reticulatae 18, Endothelium Corneum Gigeriae Galli 18, Radix Et Rhizoma Rhei 10, Carapax Trionycis 10, Cortex Lycii 23, Radix Glehniae 39, Radix Glycyrrhizae 10, Herba Artemisiae Annuae 29, Radix Ophiopogonis 39, Ramulus Cinnamomi 8, Rhizoma Zingiberis 8, Radix Pseudostellariae 18, Fructus Trichosanthis 29, Flos Farfarae 18, Radix Asteris 20, Cortex Mori 23, Arisaema Cum Bile 8, the Radix Astragali 18 and Fructus Lycii 18.
Wherein: above-mentioned Radix Et Rhizoma Rhei is a Radix et Rhizoma Rhei (processed with wine) with embodiment 1; Above-mentioned Radix Glycyrrhizae is a Radix Glycyrrhizae (processed with honey) with embodiment 1.
The preparation method of above-mentioned syrup: said components is decocted with water twice by said ratio, each 2 hours, merge decoction liquor and filtration, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, the concentration of adding and this clear paste equivalent is 95% ethanol, left standstill after the stirring 24 hours, and removed supernatant and also reclaim ethanol, and then add and make syrup after syrup makes sugar content reach 45%.
Claims (9)
1. a Chinese patent medicine for the treatment of infantile cough is characterized in that it is the medicament of being made by the following weight parts proportion raw material: Radix Ginseng 18～22, Poria 18～22, the Rhizoma Atractylodis Macrocephalae 7～9, Pericarpium Citri Reticulatae 18～22, Endothelium Corneum Gigeriae Galli 18～22, Radix Et Rhizoma Rhei 10～14, Carapax Trionycis 18～22, Cortex Lycii 22～24, Radix Glehniae 38～40, Radix Glycyrrhizae 10～14, Herba Artemisiae Annuae 28～30, Radix Ophiopogonis 38～40, Ramulus Cinnamomi 7～9, Rhizoma Zingiberis 7～9, Radix Pseudostellariae 18～22, Fructus Trichosanthis 28～30, Flos Farfarae 18～22, Radix Asteris 18～22, Cortex Mori 22～24, Arisaema Cum Bile 7～9, the Radix Astragali 18～22 and Fructus Lycii 18～22.
2. the Chinese patent medicine of treatment infantile cough as claimed in claim 1, wherein the weight portion proportioning of each raw material is: Radix Ginseng 19, Poria 19, the Rhizoma Atractylodis Macrocephalae 7, Pericarpium Citri Reticulatae 19, Endothelium Corneum Gigeriae Galli 19, Radix Et Rhizoma Rhei 11, Carapax Trionycis 19, Cortex Lycii 22, Radix Glehniae 38, Radix Glycyrrhizae 12, Herba Artemisiae Annuae 28, Radix Ophiopogonis 38, Ramulus Cinnamomi 7, Rhizoma Zingiberis 7, Radix Pseudostellariae 20, Fructus Trichosanthis 28, Flos Farfarae 19, Radix Asteris 19, Cortex Mori 22, Arisaema Cum Bile 7, the Radix Astragali 19 and Fructus Lycii 19.
3. the Chinese patent medicine of treatment infantile cough as claimed in claim 1, wherein the weight portion proportioning of each raw material is: Radix Ginseng 22, Poria 22, the Rhizoma Atractylodis Macrocephalae 9, Pericarpium Citri Reticulatae 22, Endothelium Corneum Gigeriae Galli 22, Radix Et Rhizoma Rhei 13, Carapax Trionycis 22, Cortex Lycii 24, Radix Glehniae 40, Radix Glycyrrhizae 13, Herba Artemisiae Annuae 30, Radix Ophiopogonis 40, Ramulus Cinnamomi 9, Rhizoma Zingiberis 9, Radix Pseudostellariae 22, Fructus Trichosanthis 30, Flos Farfarae 22, Radix Asteris 22, Cortex Mori 24, Arisaema Cum Bile 9, the Radix Astragali 22 and Fructus Lycii 22.
4. as the Chinese patent medicine of claim 1,2 or 3 described treatment infantile cough, wherein said Radix Et Rhizoma Rhei is a Radix et Rhizoma Rhei (processed with wine); Described Radix Glycyrrhizae is a Radix Glycyrrhizae (processed with honey).
5. as the Chinese patent medicine of claim 1,2 or 3 described treatment infantile cough, it is characterized in that said medicament is granule or oral liquid or syrup.
6. the Chinese patent medicine of treatment infantile cough as claimed in claim 4 is characterized in that said medicament is granule or oral liquid or syrup.
7. as the preparation method of the Chinese patent medicine of the described treatment infantile cough of arbitrary claim in the claim 1～4, it is characterized in that: it may further comprise the steps: described component is decocted with water twice by described proportioning, each 2 hours, merge decoction liquor and filtration, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, the concentration of adding and this clear paste equivalent is 95% ethanol, left standstill after the stirring 24 hours, get supernatant and reclaim ethanol, and then further to be condensed into 50 ℃ of following relative densities be 1.30～1.32 extractum, add sucrose, make granule.
8. as the preparation method of the Chinese patent medicine of the described treatment infantile cough of arbitrary claim in the claim 1～4, it is characterized in that: it may further comprise the steps: described component is decocted with water twice by described proportioning, each 2 hours, merge decoction liquor and filtration, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, the concentration of adding and this clear paste equivalent is 95% ethanol, left standstill after the stirring 24 hours, get supernatant and reclaim ethanol, and then the adding suitable quantity of water, make oral liquid after filtration and the sterilization.
9. as the preparation method of the Chinese patent medicine of the described treatment infantile cough of arbitrary claim in the claim 1～4, it is characterized in that: it may further comprise the steps: described component is decocted with water twice by described proportioning, each 2 hours, merge decoction liquor and filtration, it is 1.08～1.10 clear paste that filtrate is condensed into 50 ℃ of following relative densities, the concentration of adding and this clear paste equivalent is 95% ethanol, left standstill after the stirring 24 hours, get supernatant and reclaim ethanol, and then add and to make syrup after syrup makes sugar content reach 45%.
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| CN103989931A (en) * | 2014-05-30 | 2014-08-20 | 李雪梅 | Traditional Chinese medicine for treating infantile cough and preparation method thereof |
| CN104147334A (en) * | 2014-08-19 | 2014-11-19 | 孙淑芬 | Traditional Chinese medicine formula capable of eliminating phlegm |
| CN105412858A (en) * | 2015-11-19 | 2016-03-23 | 岳海棠 | Syrup and preparation method thereof |
| CN106729510A (en) * | 2016-09-21 | 2017-05-31 | 深圳市得道中医馆管理有限责任公司 | A kind of application of Chinese medicine composition and preparation method thereof and treatment lung cancer |
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