CN106074912A - A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease - Google Patents
A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease Download PDFInfo
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- CN106074912A CN106074912A CN201610699043.2A CN201610699043A CN106074912A CN 106074912 A CN106074912 A CN 106074912A CN 201610699043 A CN201610699043 A CN 201610699043A CN 106074912 A CN106074912 A CN 106074912A
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Abstract
The present invention relates to a kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease, belong to Chinese herbal medicine preparation technology field.The Chinese medicine preparation of this treatment cardiovascular and cerebrovascular disease uses ten Six-element Chinese herbal medicine to make, and the present invention utilizes the comprehensive co-action for treating cardiovascular and cerebrovascular disease of ten Six-element crude drug, little to human body side effect, decocts without patient.There is Therapeutic Method easy, cheap, evident in efficacy feature.Prevention and treatment cardiovascular and cerebrovascular disease there is well effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease, belong to Chinese herbal medicine preparation technology field.
Background technology
Cardiovascular and cerebrovascular disease is the commonly encountered diseases of a kind of serious threat human health, and within particularly more than 50 years old, middle-aged and elderly people is healthy
Commonly encountered diseases, refer to the heart owing to hyperlipemia, hyperlipidemia, atherosclerosis and hypertension etc. are caused, brain and
There is ischemic or hemorrhage in body tissue.It it has been the common and frequently-occurring disease since China's entrance aged society.People at present
Great majority use the means of fall three-hypers to prevent and treat cardiovascular and cerebrovascular disease, but the most medication for blood pressure lowering, it is
Make bloody path unimpeded by angiectatic mode.But after such medicine of life-time service, can make blood vessel that medicine tends to paralysis,
Make effect of drugs reduce eventually or lost efficacy so that causing the hidden danger of cardiovascular and cerebrovascular disease not to be eliminated.
Summary of the invention
It is an object of the invention to: provide one to be formed by prepared from traditional Chinese medicines, for the pathogeny of cardiovascular and cerebrovascular disease,
Blood circulation promoting and blood stasis dispelling, invigorating qi and dredging collateral, to reach the Chinese medicine preparation of the treatment cardiovascular and cerebrovascular disease for the treatment of both the principal and secondary aspects of a disease purpose.
The present invention is to realize above-mentioned purpose by following technical solution:
A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease, it is characterised in that: it is made up of the raw material of Chinese medicine of following weight parts:
(unit: gram)
Radix Astragali 18-22 Semen Persicae 4-8
Flos Carthami 4-8 Radix Angelicae Sinensis 4-8
Radix Paeoniae Rubra 4-8 Rhizoma Chuanxiong 4-8
Fructus Crataegi 12-16 Radix Salviae Miltiorrhizae 12-16
Pollen Typhae 4-8 Radix Achyranthis Bidentatae 6-10
Radix Rehmanniae 4-8 Radix Puerariae 8-12
Radix Platycodonis 4-8 stir-baked Fructus Aurantii in bran 4-8
Radix Bupleuri 4-8 Radix Glycyrrhizae 1-4
The preparation present invention treats Chinese medicine preparation preferred weight part ratio range of cardiovascular and cerebrovascular disease:
Radix Astragali 19-21 Semen Persicae 5-7
Flos Carthami 5-7 Radix Angelicae Sinensis 5-7
Radix Paeoniae Rubra 5-7 Rhizoma Chuanxiong 5-7
Fructus Crataegi 13-15 Radix Salviae Miltiorrhizae 13-15
Pollen Typhae 5-7 Radix Achyranthis Bidentatae 7-9
Radix Rehmanniae 5-7 Radix Puerariae 9-11
Radix Platycodonis 5-7 stir-baked Fructus Aurantii in bran 5-7
Radix Bupleuri 5-7 Radix Glycyrrhizae 1-3
The preparation present invention treats Chinese medicine preparation optimum weight part ratio range of cardiovascular and cerebrovascular disease:
The Radix Astragali 20 Semen Persicae 6
Flos Carthami 6 Radix Angelicae Sinensis 6
Radix Paeoniae Rubra 6 Rhizoma Chuanxiong 6
Fructus Crataegi 14 Radix Salviae Miltiorrhizae 14
Pollen Typhae 6 Radix Achyranthis Bidentatae 8
Radix Rehmanniae 6 Radix Puerariae 10
Radix Platycodonis 6 stir-baked Fructus Aurantii in bran 6
Radix Bupleuri 6 Radix Glycyrrhizae 2
The preparation method of the Chinese medicine preparation of above-mentioned treatment cardiovascular and cerebrovascular disease comprises the following steps:
1), by the Radix Astragali of above-mentioned weight portion, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae, the Radix Rehmanniae
Huang, Radix Puerariae, Radix Platycodonis, stir-baked Fructus Aurantii in bran, Radix Bupleuri, Radix Glycyrrhizae, respectively boiling three times, 1.2 hours for the first time, for the second time, for the third time
Each 1 hour, filter, collecting decoction;
2), above-mentioned gained decocting liquid is concentrated into according to a conventional method;The concentration adding concentrated medicament double weight after cooling is 60%
Ethanol stir, after stand 24 little layereds at normal temperatures and pressures;
3), by step 2 supernatant take out, after reclaim ethanol according to a conventional method;Supernatant after reclaiming ethanol is centrifuged, and presses
After conventional method concentrates, room temperature cools down, and filters;
4), at protein sugar and the sorbic acid of 1.6-2 part weight adding 1.6-2 part weight in the admixing medical solutions that step 3 processes
Potassium;Add essence by the weight ratio of 100:3 afterwards and stir;Then add the purified water stirring of 1000 ml;Gained medicinal liquid divides according to quantity
Bag, the Chinese medicine preparation finished product for the treatment of cardiovascular and cerebrovascular disease.
Character: this product is brown color liquid, and feeble QI, mildly bitter flavor are puckery, has the precipitation that can shake up a little.
Function cures mainly: benefiting QI for activating blood circulation.Prevention and apoplexy and coronary heart disease.And apoplexy sequela, coronary disease caused by blood stasis due to qi deficiency
Sick, hyperlipemia.
The present invention is based on the research pathogenetic to cardiovascular and cerebrovascular disease of motherland's Chinese medicine and Therapeutic Principle, with reference to modern
The scientific achievement of Chinese medical theory research, uses a large amount of Qi-tonifying drugs to match with a small amount of blood circulation promoting medicine by theory of Chinese medical science prescription so that it is tool
There is the prosperous blood of gas, invigorate blood circulation and don't just hinder, playing effect of collaterals altogether.The Radix Astragali in the present invention, the vigour of big tonifying the spleen and stomach,
Making the prosperous blood of gas, the stasis of blood goes network to lead to;Semen Persicae removing blood stasis row is stagnant and moisturizes;Flos Carthami blood circulation promoting and blood stasis dispelling, with pain relieving, is monarch drug altogether.Radix Angelicae Sinensis is longer than work
Blood, double can nourish blood, and has blood stasis dispelling and non-blood trouble wonderful, with Radix Paeoniae Rubra, Rhizoma Chuanxiong principal drug assistance blood circulation promoting and blood stasis dispelling;Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae
Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, conducting blood to flow downwards, is ministerial drug altogether.Radix Rehmanniae, Radix Puerariae nourish blood tonifying YIN, heat clearing and blood circulation promoting;Radix Platycodonis, parched with bran trifoliate orange
Shell, one rise and one drop, the chest stuffiness relieving circulation of qi promoting;Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, rises and reaches clear sun, Radix Platycodonis and the same use of stir-baked Fructus Aurantii in bran, is especially apt to regulating qi-flowing for activating stagnancy, makes
Gas row then blood, is adjuvant drug.Radix Platycodonis energy medicine carrying are up, have concurrently and make medicine be used;Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, also for making medicine, close and
With it, making blood stasis of blood activating QI row alive, the most all diseases more, and then reach the good result to cardiovascular and cerebrovascular disease treating both the principal and secondary aspects of a disease.
In the above-mentioned raw material of Chinese medicine component of the present invention, property feature and effect of every component raw material of Chinese medicine medicine are as follows:
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Benefiting QI for strengthening the superficies, diuretic, evacuation of pus sore.For deficiency of spleen-QI and stomach-QI, insufficiency of vital energy and blood, Qi and blood deficiency.
Semen Persicae: bitter is flat.GUIXIN, liver, lung, large intestine channel.Promoting blood flow to regulate menstruation, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea dysmenorrhea,
Abdominal mass abdominal mass mass in the abdomen, lung abscess acute appendicitis, tumbling and swelling, dryness of the intestine constipation.
Flos Carthami: acrid in the mouth, warm in nature.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, stimulates the menstrual flow.For amenorrhea, macule color is dark, traumatic injury congestive edema, bone
Folding pain etc..
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.Replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Wither for blood deficiency
Huang, asthenia cold abdominalgia, rheumatism arthromyodynia, traumatic injury, ulcer sores.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Nutrient blood, blood stasis amenorrhea, traumatic injury is entered for heat
Damage, liver-heat.
Rhizoma Chuanxiong: pungent, temperature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, puerperal abdonimal pain, limb
Body is numb, traumatic injury, wind-damp numbness.
Fructus Crataegi: sour, sweet, tepor.Enter spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For eating accumulation, dyspepsia is not changed,
Stimulate the menstrual flow, amenorrhea.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold.GUIXIN, pericardium, Liver Channel.Promoting blood flow to regulate menstruation, removing heat from blood eliminating carbuncle, nourishing blood to tranquillize the mind.For menstruation not
Adjusting, abdominal mass abdominal mass is gathered, and unconsciousness due to high fever, painstaking effort are not supported.
Pollen Typhae: sweet, flat.Return liver, pericardium channel.Hemostasis, blood stasis dispelling, diuresis.For spitting blood, epistaxis, traumatic hemorrhage, amenorrhea leads to
Warp, blood strangury and dry pain.
Radix Achyranthis Bidentatae: bitter, sour is flat.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome.For amenorrhea, dysmenorrhea, traumatic injury damages
Wound, toothache, excessive rising of liver-YANG.
Radix Rehmanniae: sweet, bitter, cold.Enter the heart, liver, kidney channel.Clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, for thermal burn the moon liquid, interior-heat is quenched one's thirst,
Consumption of YIN caused by febrile disease.
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Attach to the lung and stomach meridians.Expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.Do not solve for exterior syndrome,
Diarrhea due to hypofunction of the spleen, interior-heat quenches one's thirst, exterior syndrome due to wind-cold.
Radix Platycodonis: bitter in the mouth, pungent, property is put down.Return lung meridian.Lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.For cough with copious phlegm, lung abscess vomiting pus, expectorant
Choke is stagnant, and exopathogen violates lung.
Stir-baked Fructus Aurantii in bran: bitter, pungent, sour, temperature.Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.Coercing the stagnation of QI for breast, distension aches
Bitterly, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention;Gastroptosis, proctoptosis, sub-official prolapses.
Radix Bupleuri: bitter, cold nature.Return liver, gallbladder meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang.For cold, fever, stagnation of liver-QI
The stagnation of QI, depression of liver-QI, collapse of QI.
Radix Glycyrrhizae: the flat taste of property is sweet, GUIXIN, lung, spleen, stomach warp.Tool invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain, the mitigation property of medicine it
Merit.
The present invention having the beneficial effects that compared with prior art:
The Chinese medicine preparation of this treatment cardiovascular and cerebrovascular disease uses ten Six-element Chinese herbal medicine to make, and utilizes the comprehensive association of ten Six-element crude drug
Same-action treatment cardiovascular and cerebrovascular disease, little to human body side effect, decoct without patient.There is Therapeutic Method easy, cheap,
Feature evident in efficacy.Prevention and treatment cardiovascular and cerebrovascular disease there is well effect.
In order to the present invention curative effect to treatment cardiovascular and cerebrovascular disease is described, the present invention has carried out clinic to 100 patients and has controlled
Treating and observe, its clinical data is as follows:
1, general data, 100 experimenters, suffer from cardiovascular and cerebrovascular disease, wherein 50 experimenters are compiled as observation group;50 realities
The person of testing enrolls matched group, takes common drug and treats cardiovascular and cerebrovascular disease.
2, diagnosis basis:
1) heart and brain color ultrasound, electrocardiogram, the coherence check of CT sheet;
2) Chinese medical discrimination: deficiency of both the heart and spleen, disarmony between the heart and kidney, hyperactivity of heart-fire liver-yang are got angry, qi depression to blood stasis, deficiency of qi and blood, the hepatic and renal YIN deficiency.
3, efficacy assessment standard:
Curing: various Chinese and western medicine clinical symptoms are normal, auxiliary examination result support is cured;
Effective: various Chinese and western medicine clinical symptoms are obviously improved, auxiliary examination result is supported effective;
Effective: various Chinese and western medicine clinical symptoms are improved, auxiliary examination result is supported effectively;
Invalid: various Chinese and western medicine clinical symptoms are without improving;
Deteriorate: various Chinese and western medicine clinical symptoms substantially deteriorate.
4, observed data statistical table is followed the tracks of
Detailed description of the invention
Below embodiments of the present invention are described in detail:
Embodiment 1:
First each raw material of Chinese medicine is weighed by following each embodiment: (unit: gram)
The preparation method of the Chinese medicine preparation of the various embodiments described above treatment cardiovascular and cerebrovascular disease is:
By the Radix Astragali of above-mentioned weight portion, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae, Radix Rehmanniae, Pueraria lobota
Root, Radix Platycodonis, stir-baked Fructus Aurantii in bran, Radix Bupleuri, Radix Glycyrrhizae, respectively boiling three times, 1.2 hours for the first time, for the second time, the most each 1 little
Time, filter, collecting decoction.The decocting liquid of merging is concentrated into according to a conventional method;The dense of concentrated medicament double weight is added after cooling
Degree be 60% ethanol stirring, after stand 24 little layereds at normal temperatures and pressures.Will layering after supernatant take out, after routinely
Method reclaims ethanol;Supernatant after reclaiming ethanol is centrifuged, and concentrates according to a conventional method;It is subsequently adding the egg of 1.6-2 part weight
White sugar and the potassium sorbate of 1.6-2 part weight;Add essence by the weight ratio of 100:3 afterwards and stir;Add the pure of 1000 ml
Change water stirring;Gained medicinal liquid, by metering subpackage, obtains, the Chinese medicine preparation finished product for the treatment of cardiovascular and cerebrovascular disease.
Claims (3)
1. the Chinese medicine preparation treating cardiovascular and cerebrovascular disease, it is characterised in that: it is made up of the raw material of following weight parts:
Radix Astragali 18-22 Semen Persicae 4-8
Flos Carthami 4-8 Radix Angelicae Sinensis 4-8
Radix Paeoniae Rubra 4-8 Rhizoma Chuanxiong 4-8
Fructus Crataegi 12-16 Radix Salviae Miltiorrhizae 12-16
Pollen Typhae 4-8 Radix Achyranthis Bidentatae 6-10
Radix Rehmanniae 4-8 Radix Puerariae 8-12
Radix Platycodonis 4-8 stir-baked Fructus Aurantii in bran 4-8
Radix Bupleuri 4-8 Radix Glycyrrhizae 1-4.
The Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease the most according to claim 1, it is characterised in that: it is by following weight parts
Raw material make:
Radix Astragali 19-21 Semen Persicae 5-7
Flos Carthami 5-7 Radix Angelicae Sinensis 5-7
Radix Paeoniae Rubra 5-7 Rhizoma Chuanxiong 5-7
Fructus Crataegi 13-15 Radix Salviae Miltiorrhizae 13-15
Pollen Typhae 5-7 Radix Achyranthis Bidentatae 7-9
Radix Rehmanniae 5-7 Radix Puerariae 9-11
Radix Platycodonis 5-7 stir-baked Fructus Aurantii in bran 5-7
Radix Bupleuri 5-7 Radix Glycyrrhizae 1-3.
The Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease the most according to claim 1, it is characterised in that: it is by following weight parts
Raw material make:
The Radix Astragali 20 Semen Persicae 6
Flos Carthami 6 Radix Angelicae Sinensis 6
Radix Paeoniae Rubra 6 Rhizoma Chuanxiong 6
Fructus Crataegi 14 Radix Salviae Miltiorrhizae 14
Pollen Typhae 6 Radix Achyranthis Bidentatae 8
Radix Rehmanniae 6 Radix Puerariae 10
Radix Platycodonis 6 stir-baked Fructus Aurantii in bran 6
Radix Bupleuri 6 Radix Glycyrrhizae 2
The preparation method of the Chinese medicine preparation of above-mentioned treatment cardiovascular and cerebrovascular disease is:
1), by the Radix Astragali of above-mentioned weight portion, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae, the Radix Rehmanniae
Huang, Radix Puerariae, Radix Platycodonis, stir-baked Fructus Aurantii in bran, Radix Bupleuri, Radix Glycyrrhizae, respectively boiling three times, 1.2 hours for the first time, for the second time, for the third time
Each 1 hour, filter, collecting decoction;
2), above-mentioned gained decocting liquid is concentrated into according to a conventional method;The concentration adding concentrated medicament double weight after cooling is 60%
Ethanol stir, after stand 24 little layereds at normal temperatures and pressures;
3), by step 2 supernatant take out, after reclaim ethanol according to a conventional method;Supernatant after reclaiming ethanol is centrifuged, and presses
After conventional method concentrates, room temperature cools down, and filters;
4), at protein sugar and the sorbic acid of 1.6-2 part weight adding 1.6-2 part weight in the admixing medical solutions that step 3 processes
Potassium;Add essence by the weight ratio of 100:3 afterwards and stir;Then add the purified water stirring of 1000 ml;Gained medicinal liquid divides according to quantity
Bag, the Chinese medicine preparation finished product for the treatment of cardiovascular and cerebrovascular disease.
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Publication number | Priority date | Publication date | Assignee | Title |
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CN107648422A (en) * | 2017-08-25 | 2018-02-02 | 刘志聪 | A kind of Chinese medicine with blood circulation invigorating efficacies |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1096697A (en) * | 1993-06-24 | 1994-12-28 | 乐清健生保健品有限公司 | A kind of Chinese medicine electuary of preventing and treating cardiovascular and cerebrovascular disease |
CN1465386A (en) * | 2002-06-24 | 2004-01-07 | 李兆红 | Chinese medicine preparation for treating cardio-cerebral vascular disease |
CN102335380A (en) * | 2010-07-20 | 2012-02-01 | 戴海清 | Drug for treating cardiovascular and cerebrovascular diseases, and preparation method thereof |
CN104606513A (en) * | 2015-02-11 | 2015-05-13 | 青岛市市立医院 | Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine |
-
2016
- 2016-08-22 CN CN201610699043.2A patent/CN106074912B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1096697A (en) * | 1993-06-24 | 1994-12-28 | 乐清健生保健品有限公司 | A kind of Chinese medicine electuary of preventing and treating cardiovascular and cerebrovascular disease |
CN1465386A (en) * | 2002-06-24 | 2004-01-07 | 李兆红 | Chinese medicine preparation for treating cardio-cerebral vascular disease |
CN102335380A (en) * | 2010-07-20 | 2012-02-01 | 戴海清 | Drug for treating cardiovascular and cerebrovascular diseases, and preparation method thereof |
CN104606513A (en) * | 2015-02-11 | 2015-05-13 | 青岛市市立医院 | Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine |
Non-Patent Citations (1)
Title |
---|
张印等: "补阳还五汤治疗心脑血管疾病的辨治分析", 《中国临床康复》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107648422A (en) * | 2017-08-25 | 2018-02-02 | 刘志聪 | A kind of Chinese medicine with blood circulation invigorating efficacies |
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