CN1169886A - 血液过滤器 - Google Patents
血液过滤器 Download PDFInfo
- Publication number
- CN1169886A CN1169886A CN97102992A CN97102992A CN1169886A CN 1169886 A CN1169886 A CN 1169886A CN 97102992 A CN97102992 A CN 97102992A CN 97102992 A CN97102992 A CN 97102992A CN 1169886 A CN1169886 A CN 1169886A
- Authority
- CN
- China
- Prior art keywords
- blood
- blood filter
- filtrate outlet
- blood plasma
- filter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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Images
Classifications
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01D39/2003—Glass or glassy material
- B01D39/2017—Glass or glassy material the material being filamentary or fibrous
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/20—Accessories; Auxiliary operations
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/12—Composite membranes; Ultra-thin membranes
- B01D69/1213—Laminated layers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/14—Specific spacers
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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Abstract
Description
血细胞比容值(%) | 20 41 48 59 68 | |
回收的血浆体积(μl) | 本发明的实施例2 | 540 4l0 325 2l5 180 |
对照例3 | 200 130 80 35 10 |
Claims (10)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP007692/1996 | 1996-01-19 | ||
JP8007692A JPH09196911A (ja) | 1996-01-19 | 1996-01-19 | 血液濾過ユニット |
JP007692/96 | 1996-01-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1169886A true CN1169886A (zh) | 1998-01-14 |
CN1108181C CN1108181C (zh) | 2003-05-14 |
Family
ID=11672836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN97102992A Expired - Lifetime CN1108181C (zh) | 1996-01-19 | 1997-01-19 | 血液过滤器 |
Country Status (6)
Country | Link |
---|---|
US (2) | US5979669A (zh) |
EP (2) | EP0785012B1 (zh) |
JP (1) | JPH09196911A (zh) |
KR (1) | KR100446030B1 (zh) |
CN (1) | CN1108181C (zh) |
DE (2) | DE69720565T2 (zh) |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3664286B2 (ja) * | 1996-12-24 | 2005-06-22 | 富士写真フイルム株式会社 | 血液濾過ユニット |
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US6360595B1 (en) * | 2001-03-16 | 2002-03-26 | Ethicon Endo-Surgery, Inc. | Liquid measuring device and method of using |
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EP1477804A4 (en) * | 2002-02-27 | 2016-12-28 | Pfaff Medical Gmbh | PLASMA OR SERUM SEPARATION INSTRUMENT, PLASMA OR SERUM COLLECTION METHOD, PLASMA OR SERUM SEPARATION METHOD, TEST MEDIUM AND GLASS FIBER |
US6723236B2 (en) * | 2002-03-19 | 2004-04-20 | Waters Investments Limited | Device for solid phase extraction and method for purifying samples prior to analysis |
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US7927810B2 (en) | 2002-11-19 | 2011-04-19 | Katsuya Togawa | Plasma or serum separation membrane and filter apparatus including the plasma or serum separation membrane |
JP2004294388A (ja) * | 2003-03-10 | 2004-10-21 | Arkray Inc | 成分分析装置 |
EP1683566A4 (en) * | 2003-10-17 | 2008-09-24 | Fujifilm Corp | POROUS FILM CARTRIDGE |
US7128836B2 (en) * | 2004-03-08 | 2006-10-31 | Potito De Paolis | Dialysis device |
WO2005088300A1 (en) * | 2004-03-16 | 2005-09-22 | Fuji Photo Film Co., Ltd. | Assay chip |
CN1989409A (zh) * | 2004-05-27 | 2007-06-27 | 荣研化学株式会社 | 用于采出生物试样的工具和用于采出生物试样的方法 |
US7799235B2 (en) | 2004-07-23 | 2010-09-21 | Contech Stormwater Solutions, Inc. | Fluid filter system and related method |
JP2006038512A (ja) * | 2004-07-23 | 2006-02-09 | Fuji Photo Film Co Ltd | 血液濾過用ガラス繊維フィルター、血液濾過器具および血液分析素子 |
JP2006038525A (ja) | 2004-07-23 | 2006-02-09 | Fuji Photo Film Co Ltd | 液体濾過器具及び乾式分析素子 |
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US7958652B2 (en) * | 2005-01-07 | 2011-06-14 | Bissell Homecare Inc. | Extraction cleaning with plenum and air outlets facilitating air flow drying |
US8414778B2 (en) * | 2005-05-17 | 2013-04-09 | Universal Bio Research Co., Ltd. | Filtration method, filter-incorporated tip, and filtration device |
US7641055B2 (en) * | 2005-11-10 | 2010-01-05 | Donaldson Company, Inc. | Polysulfone and poly(N-vinyl lactam) polymer alloy and fiber and filter materials made of the alloy |
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DE102013010724A1 (de) * | 2013-06-27 | 2014-12-31 | Mann+Hummel Gmbh | Polymeres Vollbluthohlfasermembranfiltermedium und Verwendung davon zum Abtrennen von Blutplasma/-serum von Vollblut |
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GB201505417D0 (en) * | 2015-03-30 | 2015-05-13 | Whatman Gmbh | Improvements in and relating to polymeric membranes |
JP6820865B2 (ja) | 2015-04-29 | 2021-01-27 | ペルキネルマー ヘルス サイエンシーズ, インコーポレイテッド | 試料収集および送達装置 |
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USD920534S1 (en) | 2018-12-21 | 2021-05-25 | CanaryQ, Inc. | Blood sample filtration device |
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KR102171711B1 (ko) * | 2020-04-17 | 2020-10-29 | (주)메디라인액티브코리아 | 수액라인용 공기제거기 |
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Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE329117C (de) | 1916-08-21 | 1920-11-15 | Richard Zsigmondy Dr | Membranfilter und Verfahren zu deren Herstellung |
US3260413A (en) | 1964-08-31 | 1966-07-12 | Scientific Industries | Automatic chemical analyzer |
US3368872A (en) | 1964-08-31 | 1968-02-13 | Scientific Industries | Automatic chemical analyzer |
US3649505A (en) | 1969-03-03 | 1972-03-14 | Beckman Instruments Inc | Ammonia sensor |
US3663374A (en) * | 1970-08-14 | 1972-05-16 | Geomet | Method and apparatus for quantitating enzyme activity |
US3992158A (en) | 1973-08-16 | 1976-11-16 | Eastman Kodak Company | Integral analytical element |
JPS5392195A (en) | 1977-01-25 | 1978-08-12 | Dojindo Lab | Simple rapid determination method and apparatus for volatile matter in aqueous solution |
IT1125121B (it) | 1979-05-23 | 1986-05-14 | Ideal Standard Spa | Stampo per la colatura di un materiale ceramico in forma di barbottina |
JPS562094A (en) | 1979-06-21 | 1981-01-10 | Tokyo Shibaura Electric Co | Optical measuring system using optical code plate |
JPS5612640A (en) | 1979-07-11 | 1981-02-07 | Nissha Printing Co Ltd | Simultaneously regenerating method for used developer and used bleaching bath |
JPS5615051A (en) | 1979-07-18 | 1981-02-13 | Hitachi Ltd | Semiconductor device with multilayer wiring |
JPS5616187A (en) | 1979-07-18 | 1981-02-16 | Hitachi Ltd | Display unit |
JPS5686911A (en) | 1979-12-14 | 1981-07-15 | Kanegafuchi Chem Ind Co Ltd | Preparation of polyvinyl chloride having improved thermal stability |
JPS5766359A (en) | 1980-10-09 | 1982-04-22 | Fuji Photo Film Co Ltd | Sheet-like material for analysis |
JPS6227006A (ja) | 1985-07-27 | 1987-02-05 | Fuji Photo Film Co Ltd | 微孔性膜 |
US4631050A (en) * | 1985-09-24 | 1986-12-23 | Reed Charles C | Autotransfusion system and method |
US4839296A (en) | 1985-10-18 | 1989-06-13 | Chem-Elec, Inc. | Blood plasma test method |
JPS62138756A (ja) | 1985-12-12 | 1987-06-22 | Fuji Photo Film Co Ltd | 一体型多層分析要素 |
US4902481A (en) * | 1987-12-11 | 1990-02-20 | Millipore Corporation | Multi-well filtration test apparatus |
US5423989A (en) * | 1988-05-19 | 1995-06-13 | Chemtrack, Inc. | Plasma forming device |
JPH02105043A (ja) | 1988-10-14 | 1990-04-17 | Fuji Photo Film Co Ltd | 一体型多層分析要素の製造方法 |
JPH02208565A (ja) | 1989-02-09 | 1990-08-20 | Fuji Photo Film Co Ltd | 血液から血漿を分離する方法、器具、およびこれを用いる分析要素 |
JP2864035B2 (ja) | 1989-02-09 | 1999-03-03 | 富士写真フイルム株式会社 | 全血分析要素 |
GB2232599A (en) * | 1989-06-08 | 1990-12-19 | Summers Dr Julie Andrea | One-step blood to plasma device |
JPH04208856A (ja) | 1990-12-03 | 1992-07-30 | Sanwa Kagaku Kenkyusho Co Ltd | 全血から血清又は血漿を分離する方法および器具 |
JPH0552463A (ja) | 1991-08-28 | 1993-03-02 | Sharp Corp | 冷凍冷蔵庫 |
US5223133A (en) * | 1991-11-21 | 1993-06-29 | Millipore Corporation | Multi-filter analytical apparatus |
JPH05188053A (ja) * | 1992-01-10 | 1993-07-27 | Sanwa Kagaku Kenkyusho Co Ltd | 血液から血清又は血漿成分を分離する器具 |
US5460777A (en) * | 1992-03-16 | 1995-10-24 | Fuji Photo Film Co., Ltd. | Analytical element for whole blood analysis |
US5589399A (en) * | 1994-10-21 | 1996-12-31 | First Medical, Inc. | System and method for plasma separation and measurement |
US5603900A (en) * | 1995-05-19 | 1997-02-18 | Millipore Investment Holdings Limited | Vacuum filter device |
-
1996
- 1996-01-19 JP JP8007692A patent/JPH09196911A/ja active Pending
-
1997
- 1997-01-16 DE DE69720565T patent/DE69720565T2/de not_active Expired - Lifetime
- 1997-01-16 EP EP97100603A patent/EP0785012B1/en not_active Expired - Lifetime
- 1997-01-16 EP EP02021865A patent/EP1291062B1/en not_active Expired - Lifetime
- 1997-01-16 DE DE69732928T patent/DE69732928T2/de not_active Expired - Lifetime
- 1997-01-17 US US08/784,481 patent/US5979669A/en not_active Expired - Lifetime
- 1997-01-18 KR KR1019970001350A patent/KR100446030B1/ko not_active IP Right Cessation
- 1997-01-19 CN CN97102992A patent/CN1108181C/zh not_active Expired - Lifetime
-
1999
- 1999-04-12 US US09/290,650 patent/US6170671B1/en not_active Expired - Fee Related
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CN114062575A (zh) * | 2021-11-29 | 2022-02-18 | 杭州富集生物科技有限公司 | 富集设备及多样品连续自动富集方法 |
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DE69720565D1 (de) | 2003-05-15 |
JPH09196911A (ja) | 1997-07-31 |
DE69732928T2 (de) | 2005-09-22 |
KR970058731A (ko) | 1997-08-12 |
EP1291062A3 (en) | 2004-06-23 |
KR100446030B1 (ko) | 2004-12-23 |
US5979669A (en) | 1999-11-09 |
EP1291062A2 (en) | 2003-03-12 |
EP1291062B1 (en) | 2005-03-30 |
DE69720565T2 (de) | 2003-11-27 |
DE69732928D1 (de) | 2005-05-04 |
CN1108181C (zh) | 2003-05-14 |
EP0785012B1 (en) | 2003-04-09 |
US6170671B1 (en) | 2001-01-09 |
EP0785012A1 (en) | 1997-07-23 |
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