CN115300427A - Efficacy oil for improving skin problem of staying up at night and preparation method thereof - Google Patents

Efficacy oil for improving skin problem of staying up at night and preparation method thereof Download PDF

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CN115300427A
CN115300427A CN202210972053.4A CN202210972053A CN115300427A CN 115300427 A CN115300427 A CN 115300427A CN 202210972053 A CN202210972053 A CN 202210972053A CN 115300427 A CN115300427 A CN 115300427A
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oil
skin
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staying
overnight
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钱贵蓉
侯如标
陈苗苗
赵群
张燎原
刘倩
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Hangzhou Shucai Network Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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Abstract

The invention discloses an efficacy oil for improving skin problems of staying up all night and a preparation method thereof. According to the invention, tea polyphenol, jasmine flower extract and alpine edelweiss callus extract can strengthen the vitality of the skin damaged in an overnight state from three aspects of promoting cell proliferation, strengthening cell metabolism and enhancing intercellular communication, and the effect oil for improving the skin problem in an overnight state can endow the skin damaged in an overnight state with energy, is a composition for restoring the self-repairing function of the skin and repairing various skin problems caused in an overnight state, and has a certain using effect by strengthening the vitality of the skin damaged in an overnight state, restoring the normal function of the skin, improving the current situation of skin problems due to the reduction of vitality of the cells caused in an overnight state, and preventing the skin from being burdened by necessary overnight state.

Description

Efficacy oil for improving skin problems of staying up all night and preparation method thereof
Technical Field
The invention relates to the technical field of skin care products, and particularly relates to functional oil for improving the problem of overnight skin and a preparation method thereof.
Background
Today, the timing of day and night clocks is disturbed due to work or habit problems. The breaking of the biological clock has great influence on human health, and on the skin, people can more intuitively and rapidly feel the harm caused by the breaking of the biological clock, for example, as the human body stays up for a long time, cells in the skin of the human body are damaged in different degrees, the number of ATP is reduced, the working efficiency of a cell energy factory is reduced, the cell kinetic energy is insufficient due to the slow metabolism, more oxygen free radicals are accumulated, sebum secretion grease is accumulated on the surface of the skin, then the sebum is attacked by free radicals, the sebum is overoxidized, melanocytes are stimulated, melanin sources are continuously generated, the melanin transportation function is weakened, the pigmentation is caused, the skin becomes dark, the free radicals generated by the metabolism of the cells of the skin are accumulated, the cells of the human body are attacked, protein is caused, the cell activity is reduced, the division and differentiation speed is reduced, the barrier function is weakened, and the skin is easy to be sensitive.
Disclosure of Invention
The invention aims to overcome the defects in the prior art, provides the functional oil for improving the problem of overnight skin and the preparation method thereof, and can effectively solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: the efficacy oil for improving the problem of the skin staying up at night comprises a composition of triglyceride, alkane substances, wax ester substances, an active matter staying up at night and other components, and comprises the following components in percentage by weight: the composition consists of triglycerides: 0.1% -50%, alkane substance: 1-30% of wax ester substances: 1-30%, overnight active: 0.1-4%, other components: 0.1 to 1 percent;
said composition comprises triglycerides including hazelnut oil, borage oil, oat kernel oil, horse-ylang oil, perilla seed oil, olive oil unsaponifiable matter, sunflower oil, spanish sage seed oil, phytosterols;
the preparation method of the efficacy oil for improving the problem of skin staying up at night comprises the following steps:
step one, preparing raw materials: preparing a quantity of a composition comprising triglycerides, paraffinic materials, wax esters, overnight actives, and other ingredients;
step two, partially mixing, stirring and heating: mixing part of the stay-up active substances and part of the alkane substances uniformly, heating to 60-70 ℃, and then cooling to 40-50 ℃;
step three, mixing, stirring and cooling: adding the rest composition composed of triglyceride, wax ester, and alkane, stirring, cooling to 30-40 deg.C, adding other components, stirring, cooling, filtering, standing, and making into oil for improving skin problem.
Preferably, the alkane substances comprise C9-12 alkane and squalane, and the wax ester substances comprise white chinlon oil and jojoba oil.
Preferably, the overnight active comprises green tea polyphenol, jasmine cell extract, and edelweiss callus extract, and the other components comprise essential oil and vitamin E.
Preferably, the preparation process of the jasmine cell extract comprises the following steps: the method comprises the following steps of taking 2mm x 2mm healthy plant tissue small blocks from a bivalvular jasmine plant, carrying out tissue section sterilization treatment, inducing the formation of plant callus by using a certain proportion of cytokinin and auxin, applying stress and oriented induction activity to the callus, strictly screening functional fragment mother cells on the callus, carrying out mass culture on the mother cells in a culture solution, copying and storing the mother cells for subsequent mass production, carrying out mass production on the plant active cells under the conditions of strictly controlling temperature, humidity, illumination and the like and ensuring sterility, filtering the culture solution of the produced cells to obtain pure plant cells, weighing plant cells and sunflower oil with corresponding weight according to the proportion of 2.
Compared with the prior art, the invention has the beneficial effects that:
according to the invention, tea polyphenol, jasmine extract (double-petal jasmine) and alpine edelweiss (edelweiss) callus extract can enhance the vitality of the skin damaged in an overnight state from three aspects of promoting cell proliferation, strengthening cell metabolism and enhancing intercellular communication, and from the essence of the skin (cell level) and three aspects, the vitality of the skin damaged in an overnight state can be strengthened, the skin can restore the normal function, the current situation that the skin problem is caused by the reduction of the vitality of the cells in an overnight state can be improved, the skin is prevented from being burdened by necessary overnight state, the skin damaged in an overnight state can be endowed with cell energy by matching with corresponding compositions and other substances, the composition is a composition for restoring the self-repairing function of the skin and repairing various skin problems caused in an overnight state, and has a certain using effect.
Drawings
FIG. 1 is a substance composition diagram of an effective oil for improving the problem of overnight skin according to the present invention;
FIG. 2 is a graph of the composition of the present invention as a matter of triglyceride;
FIG. 3 is a substance composition diagram of the overnight active of the present invention;
FIG. 4 is a composition diagram of an alkane substance according to the present invention;
FIG. 5 is a substance composition diagram of a wax ester substance according to the present invention.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The efficacy oil for improving the problem of the skin staying up at night comprises a composition of triglyceride, alkane substances, wax ester substances, an active matter staying up at night and other components, and comprises the following components in percentage by weight: the composition consists of triglycerides: 0.1% -50%, alkane substances: 1-30%, wax ester: 1-30%, overnight active: 0.1-4%, other components: 0.1 to 1 percent;
said composition comprises triglycerides including hazelnut oil, borage oil, oat kernel oil, marulara oil, perilla seed oil, olive oil unsaponifiables, sunflower oil, canola oil, phytosterols;
the preparation method of the efficacy oil for improving the problem of overnight skin comprises the following steps:
step one, preparing raw materials: preparing a quantity of a composition comprising triglycerides, paraffinic materials, waxy ester materials, overnight actives, and other ingredients;
step two, partially mixing, stirring and heating: mixing part of the stay-up active substances and part of the alkane substances uniformly, heating to 60-70 ℃, and then cooling to 40-50 ℃;
step three, mixing, stirring and cooling: adding the rest composition composed of triglyceride, wax ester, and alkane, stirring, cooling to 30-40 deg.C, adding other components, stirring, cooling, filtering, standing, and making into oil for improving skin.
Further, the alkane substances comprise C9-12 alkane and squalane, and the wax ester substances comprise white chinlon oil and jojoba oil.
Further, the overnight active comprises green tea polyphenol, jasmine cell extract and edelweiss callus extract, and the other components comprise essential oil and vitamin E.
Further, the preparation process of the jasmine cell extract comprises the following steps: the method comprises the following steps of taking 2mm x 2mm healthy plant tissue small blocks from a bivalvular jasmine plant, carrying out tissue section sterilization treatment, inducing the formation of plant callus by using a certain proportion of cytokinin and auxin, applying stress and oriented induction activity to the callus, strictly screening functional fragment mother cells on the callus, carrying out mass culture on the mother cells in a culture solution, copying and storing the mother cells for subsequent mass production, carrying out mass production on the plant active cells under the conditions of strictly controlling temperature, humidity, illumination and the like and ensuring sterility, filtering the culture solution of the produced cells to obtain pure plant cells, weighing plant cells and sunflower oil with corresponding weight according to the proportion of 2.
In the invention, the tea polyphenol is rich in catechin, has the functions of super-strong antioxidation, blood circulation promotion and the like, but the traditional tea polyphenol is mostly water-soluble, the tea polyphenol used in the patent is esterified tea polyphenol, the human skin is a double phospholipid structure, the esterified tea polyphenol is easier to remain on the skin than the traditional tea polyphenol, and the green tea polyphenol used in the invention contains more than 80 percent of catechin, so the tea polyphenol has stronger antioxidation effect to prevent the oxidation of cell lipid and the attack of excessive free radicals on cells to generate inflammation and melanin, in addition, the tea polyphenol can also promote the network merisation of blood capillaries, strengthen the efficiency of nutrition transportation of true epidermis and further maintain the function of skin barrier;
in the present invention, a jasmine extract (double-petal jasmine): the plant is a bivalve jasmine variety originally produced in subtropical regions, and researches show that the plant can promote the resistance gene KI67 for promoting the proliferation of keratinocytes and the synthesis of filaggrin, so that the activity of the contained cells can be confirmed to improve the state of the cells with reduced intercellular communication capacity caused by ultraviolet ray damage and aging, the intercellular communication capacity is enhanced, and the purpose of cell proliferation and differentiation is achieved.
In the invention, the alpine edelweiss is a plant with strong vitality, can survive the edelweiss in the environment with high altitude, low air pressure, low temperature, low moisture and high ultraviolet rays, the part exposed out of the soil surface is rich in edelweiss acid, and the edelweiss acid has a protection effect on cell mitochondrial DNA, so that the cells are prevented from being damaged by ultraviolet rays, energy is continuously supplied to the cells, and the cells are normally proliferated and differentiated.
According to the invention, tea polyphenol, jasmine extract (double-petal jasmine) and alpine edelweiss (edelweiss) callus extract can enhance the vitality of the skin damaged in an overnight state from three aspects of promoting cell proliferation, strengthening cell metabolism and enhancing intercellular communication, and from the essence of the skin (cell level) and three aspects, the vitality of the skin damaged in an overnight state can be strengthened, the skin can restore the normal function, the current situation that the skin problem is caused by the reduction of the vitality of the cells in an overnight state can be improved, the skin is prevented from being burdened by necessary overnight state, the skin damaged in an overnight state can be endowed with cell energy by matching with corresponding compositions and other substances, the composition is a composition for restoring the self-repairing function of the skin and repairing various skin problems caused in an overnight state, and has a certain using effect.
Test examples
The patch test, the human body efficacy test and the stability test are carried out on the efficacy oil prepared by the invention:
1. stability test:
Figure BDA0003796291880000061
remarking: 5: no abnormality, 4: slight abnormality, 3: abnormality but acceptable, 2: obvious abnormality, 1: completely unacceptable.
And (4) conclusion: after a 28-day stability test, the product is recovered to room temperature under various conditions and is observed to have no abnormality.
2. Spot-sticking test:
skin closed patch test skin reaction grading standard:
Figure BDA0003796291880000062
Figure BDA0003796291880000071
skin occlusion patch test results
Figure BDA0003796291880000072
The test result shows that the 32 subjects have a rating of 0 in 30min,24h and 48h after the test object spot tester is removed, and no adverse reaction occurs.
3. Human body efficacy experiments:
and (3) testing the efficacy: screening of 35 eligible subjects for a 28 day follow-up test was performed by first stimulating lactic acid in the batch of subjects under the correct guidance of the assigned institution. The test was then performed on the subject at the time node of 0.14.28 days in this experiment with the professional instrumentation of the institution using the product pair daily, where the test dimensions included: the dimensions of skin moisture loss, redness of the skin, skin gloss, skin elasticity, skin firmness, skin roughness were measured over 28 days and the results showed that the use of the product resulted in a considerable improvement in the damaged skin in these dimensions.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (4)

1. The efficacy oil for improving the problem of the skin staying up at night comprises a composition of triglyceride, alkane substances, wax ester substances, an active matter staying up at night and other components, and is characterized in that the efficacy oil for improving the problem of the skin staying up at night comprises the following components in percentage by weight: the composition consists of triglycerides: 0.1% -50%, alkane substance: 1-30%, wax ester: 1-30%, stay up active: 0.1-4%, other components: 0.1 to 1 percent;
said composition comprises triglycerides including hazelnut oil, borage oil, oat kernel oil, horse-ylang oil, perilla seed oil, olive oil unsaponifiable matter, sunflower oil, spanish sage seed oil, phytosterols;
the preparation method of the efficacy oil for improving the problem of skin staying up at night comprises the following steps:
step one, preparing raw materials: preparing a quantity of a composition comprising triglycerides, paraffinic materials, waxy ester materials, overnight actives, and other ingredients;
step two, partially mixing, stirring and heating: mixing part of the active matter staying up all night and part of the alkane substance uniformly, heating to 60-70 ℃, and then cooling to 40-50 ℃;
step three, mixing, stirring and cooling: adding the rest composition composed of triglyceride, wax ester, and alkane, stirring, cooling to 30-40 deg.C, adding other components, stirring, cooling, filtering, standing, and making into oil for improving skin.
2. The oil for improving the problem of overnight skin as claimed in claim 1, wherein the alkane comprises C9-12 alkane and squalane, and the wax ester comprises Potentilla chinensis oil and jojoba oil.
3. The functional oil for improving the problem of the skin staying up at night as claimed in claim 1, wherein the staying up active substances comprise green tea polyphenol, jasmine cell extract and alpine edelweiss callus extract, and the other components comprise essential oil and vitamin E.
4. The oil for improving the overnight skin problem according to claim 1, wherein the jasmine cell extract is prepared by the following steps: the method comprises the following steps of taking 2mm x 2mm healthy plant tissue small blocks from a bivalvular jasmine plant, carrying out tissue section sterilization treatment, inducing the formation of plant callus by using a certain proportion of cytokinin and auxin, applying stress and oriented induction activity to the callus, strictly screening functional fragment mother cells on the callus, carrying out mass culture on the mother cells in a culture solution, copying and storing the mother cells for subsequent mass production, carrying out mass production on the plant active cells under the conditions of strictly controlling temperature, humidity, illumination and the like and ensuring sterility, filtering the culture solution of the produced cells to obtain pure plant cells, weighing plant cells and sunflower oil with corresponding weight according to the proportion of 2.
CN202210972053.4A 2022-08-12 2022-08-12 Efficacy oil for improving skin problem of staying up at night and preparation method thereof Pending CN115300427A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110812256A (en) * 2019-10-10 2020-02-21 澳宝化妆品(惠州)有限公司 Skin care composition containing borage seed extract
CN111265441A (en) * 2020-03-13 2020-06-12 佛山市奥姿美生物科技有限公司 Composition capable of enhancing skin night repair and regeneration capacity and application thereof
CN113368003A (en) * 2021-06-25 2021-09-10 广州环亚化妆品科技有限公司 Composition with overnight muscle repairing effect and preparation method and application thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110812256A (en) * 2019-10-10 2020-02-21 澳宝化妆品(惠州)有限公司 Skin care composition containing borage seed extract
CN111265441A (en) * 2020-03-13 2020-06-12 佛山市奥姿美生物科技有限公司 Composition capable of enhancing skin night repair and regeneration capacity and application thereof
CN113368003A (en) * 2021-06-25 2021-09-10 广州环亚化妆品科技有限公司 Composition with overnight muscle repairing effect and preparation method and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
上海逐本化妆品有限公司: "逐本不染茉莉白茶肌活修护精华油", Retrieved from the Internet <URL:https://hzpba.nmpa.gov.cn/gccx/chakan.html?prodId=951439571231440896&gb=G> *

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Application publication date: 20221108