CN115243719A - CTB006与Ponatinib联合应用 - Google Patents
CTB006与Ponatinib联合应用 Download PDFInfo
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- CN115243719A CN115243719A CN202180019028.8A CN202180019028A CN115243719A CN 115243719 A CN115243719 A CN 115243719A CN 202180019028 A CN202180019028 A CN 202180019028A CN 115243719 A CN115243719 A CN 115243719A
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Abstract
本文提供了抗肿瘤药物组合，其包括TRAIL‑R2激动型抗体(如CTB006)和帕纳替尼(Ponatinib)或其盐酸盐。本文还提供了肿瘤治疗方法，其包括以治疗有效量的TRAIL‑R2激动型抗体和帕纳替尼或其盐酸盐向患者给药。这二者的协同作用有助于增强肿瘤治疗效果。
Description
PCT国内申请，说明书已公开。
Claims (34)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020078158 | 2020-03-06 | ||
| CNPCT/CN2020/078158 | 2020-03-06 | ||
| PCT/CN2021/079403 WO2021175326A1 (zh) | 2020-03-06 | 2021-03-05 | CTB006与Ponatinib联合应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115243719A true CN115243719A (zh) | 2022-10-25 |
Family
ID=77614480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180019028.8A Pending CN115243719A (zh) | 2020-03-06 | 2021-03-05 | CTB006与Ponatinib联合应用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230112450A1 (zh) |
| EP (1) | EP4115902A4 (zh) |
| JP (1) | JP2023518132A (zh) |
| CN (1) | CN115243719A (zh) |
| WO (1) | WO2021175326A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023239422A2 (en) * | 2021-10-22 | 2023-12-14 | University Of Houston System | Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090136503A1 (en) * | 2006-04-30 | 2009-05-28 | Zheng Yu | Trail receptor-binding agents and uses of the same |
| CN107108736A (zh) * | 2014-11-14 | 2017-08-29 | 北京同为时代生物技术有限公司 | Trail受体结合剂及其用途 |
| CN108472359A (zh) * | 2015-08-19 | 2018-08-31 | 北京先通国际医药科技股份有限公司 | Trail受体结合剂及其用途 |
| KR20180111077A (ko) * | 2017-03-31 | 2018-10-11 | 재단법인 아산사회복지재단 | 아스피린 및 다중 키나아제 억제제를 포함하는 항암제 내성 치료용 조성물 |
| CN109641058A (zh) * | 2016-08-23 | 2019-04-16 | 吉宁特有限公司 | 治疗胰腺癌的组合疗法 |
| CN109875999A (zh) * | 2018-05-29 | 2019-06-14 | 上海交通大学医学院附属第九人民医院 | 泊那替尼在kit突变型恶性黑色素瘤中的应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202008230PA (en) * | 2018-02-28 | 2020-09-29 | Ferro Therapeutics Inc | Compounds with ferroptosis inducing activity and methods of their use |
-
2021
- 2021-03-05 WO PCT/CN2021/079403 patent/WO2021175326A1/zh unknown
- 2021-03-05 CN CN202180019028.8A patent/CN115243719A/zh active Pending
- 2021-03-05 US US17/909,658 patent/US20230112450A1/en active Pending
- 2021-03-05 EP EP21763694.3A patent/EP4115902A4/en active Pending
- 2021-03-05 JP JP2022579146A patent/JP2023518132A/ja active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090136503A1 (en) * | 2006-04-30 | 2009-05-28 | Zheng Yu | Trail receptor-binding agents and uses of the same |
| CN107108736A (zh) * | 2014-11-14 | 2017-08-29 | 北京同为时代生物技术有限公司 | Trail受体结合剂及其用途 |
| CN108472359A (zh) * | 2015-08-19 | 2018-08-31 | 北京先通国际医药科技股份有限公司 | Trail受体结合剂及其用途 |
| CN109641058A (zh) * | 2016-08-23 | 2019-04-16 | 吉宁特有限公司 | 治疗胰腺癌的组合疗法 |
| KR20180111077A (ko) * | 2017-03-31 | 2018-10-11 | 재단법인 아산사회복지재단 | 아스피린 및 다중 키나아제 억제제를 포함하는 항암제 내성 치료용 조성물 |
| CN109875999A (zh) * | 2018-05-29 | 2019-06-14 | 上海交通大学医学院附属第九人民医院 | 泊那替尼在kit突变型恶性黑色素瘤中的应用 |
Non-Patent Citations (1)
| Title |
|---|
| 高旭等: "抗DR5单抗CTB006联合5-FU对结直肠癌细胞系作用研究", 《中国医药生物技术》, vol. 6, no. 2, 10 April 2011 (2011-04-10), pages 106 - 110 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4115902A1 (en) | 2023-01-11 |
| WO2021175326A1 (zh) | 2021-09-10 |
| EP4115902A4 (en) | 2024-04-17 |
| JP2023518132A (ja) | 2023-04-27 |
| US20230112450A1 (en) | 2023-04-13 |
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