CN114949136A - Traditional Chinese medicine composition for treating chronic pharyngitis and preparation method and application thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic pharyngitis, which is prepared from the following raw material medicines in parts by weight: the invention discloses astragalus mongholicus, bighead atractylodes rhizome, divaricate saposhnikovia root, ginseng, lotus seed pulp, coix seed, fructus amomi, poria cocos, cinnamon, prepared rhizome of rehmannia and the like, and discloses a preparation method and application thereof.

Description

Traditional Chinese medicine composition for treating chronic pharyngitis and preparation method and application thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating chronic pharyngitis and a preparation method and application thereof.

Background

The western medicine considers that acute simple pharyngitis is acute inflammation of pharyngeal mucosa and submucosal tissues, and pharyngeal lymphoid tissues are often invaded. Cold and dampness are the most common inducing factors, endocrine dyscrasia and chronic systemic diseases are caused by the cold and dampness, and chronic diseases of the nose and the pharynx are also caused by the cold and dampness. The pathogeny is mainly hemolytic streptococcus. Nonhemolytic streptococci, pneumococci, staphylococci and viruses may also cause disease. Chronic pharyngitis is a diffuse pharyngeal lesion caused by chronic infection, and the chronic pharyngitis is caused by various reasons, such as repeated attack of acute pharyngitis, which turns into chronic pharyngitis, and other diseases, such as chronic nasal diseases, external bad stimulation, allergic constitution and the like, can also cause the disease.

As early as in the book of the Nei Jing, there is a discussion about chronic pharyngitis (pharyngitis), which explains the pathogenesis of pharyngitis and its acupuncture and moxibustion therapy, and suggests that the syndrome of pharyngitis has a close relationship with lung, kidney and stomach for the first time. Until Zhang Zhongjing of Han Dynasty, the symptoms of pharyngalgia due to shaoyin were discussed in more detail. In jin Kui Yao L ü e, there are discussions of "the adverse rise of fire to the upper-qi, adverse sensation in the throat, checking the adverse flow of qi and stopping the flow of qi, Mai Dong Tang". The "Shanghai treatise on Cold-induced diseases" article 334 also founds the idea of relieving sore throat with pain in the throat: for cold with syncope before fever, spontaneous sweating and sore throat, the throat is marked by arthralgia. Fever without sweating but with ease will stop, if it is not stopped, pus and blood will be discharged in stool, then the throat will not be obstructed. Related prescriptions for treating pharyngitis are created, such as Sufu decoction, Jiefeng decoction, ban Xia san and decoction, Ku Jiu decoction, Tongmai Siqi decoction, Dachengqi decoction, etc. The pathogenesis of the infantile pharyngitis is discussed in the holy economical book. The "holy economical book of diseases" infantile pharyngitis "says: diseases of pharyngitis, swelling and obstruction of throat with swelling and pain, retained fluid, disturbed respiration, alternating chills and fever, wind-heat affecting the spleen and lung, fumigating the throat, and infantile diseases with pure yang are mostly treated. "

Modern medicine has more extensive research on chronic pharyngitis. In clinical research, with the progress of etiology research, it is recognized that chronic pharyngitis is mostly caused by the infection of susceptible viruses or (and) bacteria of acute upper respiratory tract infection, and the common pathogenic bacteria are staphylococcus aureus, diplococcus pneumoniae, streptococcus and the like. The clinical diagnosis and syndrome differentiation combined research is reported, and the comprehensive treatment of chronic pharyngitis by various therapies is also summarized, but the use of chemical drugs is easy to generate drug resistance.

The Chinese patent application: CN202110621753.4 discloses a honey paste for treating chronic pharyngitis and a preparation method thereof, wherein sesame oil, walnut kernels and red dates are used as main materials, and ginger, lotus roots and other food materials are used as auxiliary materials, so that the body constitution of a human body is effectively adjusted, the phenomenon of poor transportation of the spleen of the human body can be well improved, yin is nourished, lung is cleared away, body fluid is generated, dryness is moistened, blood circulation is promoted, blood stasis is removed, heat is cleared away, phlegm is reduced, wind is dispelled, collaterals are dredged, blood is promoted, fatigue is relieved, and stagnation is dissipated.

The Chinese patent application: CN202110625229.4 discloses a traditional Chinese medicine composition for treating lung yin deficiency type chronic pharyngitis, an extract and an application thereof, and the traditional Chinese medicine composition is based on syndrome differentiation and treatment of traditional Chinese medicine and is scientifically combined with clinical practice. In the composition, the adenophora tetraphylla is used as a monarch drug for nourishing yin and moistening lung, the schisandra chinensis is used for nourishing kidney and moistening lung, the dark plum fruits astringe lung and promote fluid production, the monarch drug is used for assisting in moistening lung and relieving cough, the dried tangerine peel, the pericarpium trichosanthis and the raw hawthorn are used for reducing phlegm and promoting qi circulation, the oldenlandia diffusa is used for clearing heat and removing toxicity, the fructus chebulae immaturus and the mint are used for clearing throat, and the six drugs are used for assisting in relieving sore throat and relieving cough. Raw gan Cao dispels phlegm and relieves cough, harmonizes all the herbs, and is used as a guiding drug. The composition has remarkable treatment effect on lung yin deficiency type chronic pharyngitis, and is safe and free of toxic and side effects.

However, reports of a traditional Chinese medicine composition which is similar to the traditional Chinese medicine composition and has the effects of tonifying lung and spleen, warming kidney and strengthening yang and treating chronic pharyngitis, and a preparation method and application thereof are not found at present.

Disclosure of Invention

The first purpose of the invention is to provide a traditional Chinese medicine composition for treating chronic pharyngitis, aiming at the defects of the prior art.

The second purpose of the present invention is to provide the use of the above-mentioned Chinese medicinal composition for overcoming the disadvantages of the prior art.

The third purpose of the invention is to provide a medicine for treating chronic pharyngitis, which aims at overcoming the defects of the prior art.

A fourth object of the present invention is to provide a method for preparing the above-mentioned medicament, which addresses the deficiencies of the prior art.

In order to realize the first purpose, the invention adopts the technical scheme that:

a traditional Chinese medicine composition for treating chronic pharyngitis is prepared from the following raw material medicines in parts by weight: 20-30 parts of astragalus membranaceus, 15-25 parts of bighead atractylodes rhizome, 10-20 parts of divaricate saposhnikovia root, 10-20 parts of ginseng, 15-25 parts of lotus seed pulp, 10-20 parts of coix seed, 8-12 parts of fructus amomi, 20-30 parts of poria cocos, 8-12 parts of cinnamon, 10-20 parts of prepared rehmannia root, 20-30 parts of Chinese yam, 15-25 parts of cornus officinalis, 10-20 parts of cortex moutan, 8-16 parts of white paeony root, 8-12 parts of bulbus fritillariae cirrhosae, 10-16 parts of mint, 10-16 parts of scorched hawthorn fruit, 20-30 parts of fried malt and 8-12 parts of honey-fried licorice root.

Preferably, the traditional Chinese medicine composition is prepared from the following raw medicines in parts by weight: 25-30 parts of astragalus membranaceus, 20-25 parts of bighead atractylodes rhizome, 15-20 parts of divaricate saposhnikovia root, 15-20 parts of ginseng, 20-25 parts of lotus seed pulp, 15-20 parts of coix seed, 10-12 parts of fructus amomi, 25-30 parts of poria cocos, 10-12 parts of cinnamon, 15-20 parts of prepared rehmannia root, 25-30 parts of Chinese yam, 20-25 parts of cornus officinalis, 15-20 parts of cortex moutan, 12-16 parts of white paeony root, 10-12 parts of bulbus fritillariae cirrhosae, 12-16 parts of mint, 12-16 parts of scorched hawthorn fruit, 25-30 parts of fried malt and 10-12 parts of honey-fried licorice root.

Preferably, the clinically acceptable pharmaceutical preparation is prepared according to a conventional preparation method of the traditional Chinese medicine.

Preferably, the pharmaceutical preparation is granules, powder, capsules, tablets, decoction or oral liquid.

In order to achieve the second object, the invention adopts the technical scheme that:

the application of the traditional Chinese medicine composition in preparing a medicine for treating chronic pharyngitis.

Preferably, the chronic pharyngitis is chronic pharyngitis caused by deficiency of lung and spleen qi.

Preferably, the chronic pharyngitis is lung and spleen qi deficiency type chronic pharyngitis and kidney yang deficiency type chronic pharyngitis.

In order to achieve the third object, the invention adopts the technical scheme that:

a medicine for treating chronic pharyngitis is prepared from the traditional Chinese medicine composition.

Preferably, the medicament further comprises pharmaceutically acceptable auxiliary agents.

In order to achieve the fourth object, the invention adopts the technical scheme that:

the preparation method of the medicine comprises the following steps:

(1) taking raw material medicines: soaking radix astragali, Atractylodis rhizoma, radix Saposhnikoviae, Ginseng radix, semen Nelumbinis, Coicis semen, fructus Amomi, Poria, cortex Cinnamomi, radix rehmanniae Preparata, rhizoma Dioscoreae, Corni fructus, cortex moutan, radix Paeoniae alba, Bulbus Fritillariae Cirrhosae, herba Menthae, fructus crataegi preparata, fructus Hordei Germinatus preparata, and radix Glycyrrhizae Preparata in water for 1 hr;

(2) decocting in water for 2 times, adding 10 times of water each time, boiling and decocting for 50min for the first time and 40min for the second time, and mixing decoctions;

(3) adding pharmaceutically acceptable pharmaceutical adjuvants according to conventional process, and making into clinically acceptable granule, powder, capsule, tablet, decoction or oral liquid.

Radix astragali is root of Astragalus membranaceus bge of Leguminosae. Digging in spring and autumn, removing soil, fibrous root and root head, drying in the sun to six or seven percent, straightening, bundling and drying in the sun. The main functional indications are as follows: tonify qi, strengthen superficies, expel toxin, expel pus, induce diuresis, and promote granulation. Can be used for treating deficiency of vital energy, asthenia, chronic diarrhea, proctoptosis, spontaneous perspiration, edema, uterine prolapse, albuminuria due to chronic nephritis, diabetes, and unhealed wound.

The rhizoma Atractylodis has effects of invigorating spleen, invigorating qi, eliminating dampness, promoting diuresis, arresting sweating, and preventing miscarriage. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion. Record of "medical enlightenment": the traditional Chinese medicine composition has the effects of removing dampness and benefiting dryness, regulating the middle warmer and replenishing qi, warming the middle warmer, removing dampness in the spleen and stomach, removing stomach heat, strengthening the spleen and stomach, promoting appetite, quenching thirst and preventing miscarriage. ".

Ledebouriella root is the dried root of Saposhnikovia divaricata (Turcz.) Schischk. Digging roots of plants without flower stems in spring and autumn, removing fibrous roots and silt, and drying in the sun. Pungent and sweet in flavor, slightly warm in nature. Has the effects of dispelling pathogenic wind, relieving exterior syndrome, eliminating dampness, relieving pain, and relieving spasm.

The Ginseng radix is root of Panax ginseng C.A. Meyer of Araliaceae. The root contains various ginsenosides. Warm in nature, sweet, slightly bitter and slightly warm in taste. It enters spleen and lung meridians. Warm in nature, sweet, slightly bitter and slightly warm in taste. It enters spleen and lung meridians. Tonify primordial qi, recover pulse to stop collapse, tonify spleen and lung, promote fluid production, and induce tranquilization. Can be used for treating asthenia, collapse, cold limbs, slight pulse, spleen deficiency, anorexia, cough, asthma, and thirst due to body fluid consumption.

The semen Nelumbinis is mature seed of Nelumbo Nucifera Gaertn of Nymphaeaceae. It can be used for treating chronic diarrhea and dysentery due to spleen deficiency, spermatorrhea, urinary incontinence, metrorrhagia, leukorrhagia, palpitation, and insomnia.

The Coicis semen is dried mature kernel of Coix lacryma-jobi L.var.mayuen (Roman.) Stapf of Gramineae. Harvesting plants when fruits are mature in autumn, drying in the sun, removing fruits, drying in the sun again, removing shells, tawny seed coats and impurities, and collecting kernels. Sweet and bland in nature and taste, and cool in nature. It enters spleen, stomach and lung meridians. Has effects in promoting water penetration, removing dampness, invigorating spleen, relieving diarrhea, relieving arthralgia, expelling pus, removing toxic substance, and resolving hard mass.

The fructus Amomi is dry mature fruit of Zingiberaceae plant Amomorium villosum lour, green shell Amomorium villosum lour. Collected in summer and autumn when the fruits are ripe, dried in the sun or at low temperature. Pungent in nature and flavor and warm in nature. It enters spleen, stomach and kidney meridians. Has effects of eliminating dampness, promoting appetite, warming spleen, relieving diarrhea, regulating qi-flowing, and preventing miscarriage. Can be used for treating damp turbidity obstruction in middle energizer, abdominal distention, inappetence, deficiency-cold of spleen and stomach, emesis, diarrhea, vomiting, and threatened abortion.

Poria is dried sclerotium of Wolf of Poria cocos (Schw.) belonging to Polyporaceae. Digging for more than 7-9 months, removing silt after digging, piling up to generate sweat, spreading and drying until the surface is dry, then generating sweat, repeating for a plurality of times until wrinkles appear and most of internal water is lost, and drying in the shade to obtain Poria cocos; or cutting fresh Poria according to different parts, and drying in the shade to obtain Poria block and Poria tablet. Sweet and bland in nature and taste, mild in nature. It enters heart, lung, spleen and kidney meridians. Induce diuresis and drain dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.

Cinnamon is the dried bark of Cinnamomum cassia Presl of Lauraceae. In autumn, the seeds are peeled off and dried in the shade. Pungent and sweet in flavor and strongly hot in nature. It enters kidney, spleen, heart and liver meridians. Has the effects of tonifying fire, supporting yang, guiding fire to the origin, dispelling cold, relieving pain, and warming and dredging channels and collaterals. Can be used for treating sexual impotence, cold womb, cold pain of waist and knee, asthma due to kidney deficiency, floating of deficient yang, giddiness, conjunctival congestion, cold pain of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia, abdominal pain, dysmenorrhea, and amenorrhea.

The prepared rhizome of rehmannia has the main functions of nourishing yin and enriching blood. It is indicated for deficiency of yin and blood, atrophy and weakness of waist and knees, fatigue, cough, steaming bone, seminal emission, metrorrhagia, menoxenia, diabetes, scanty urine, deafness and blurred vision.

The rhizoma Dioscoreae is dried rhizome of Dioscorea opposita Thunb of Dioscoreaceae. Digging in 11-12 months, cutting off root, cleaning soil, scraping off outer skin with bamboo knife, and sun drying or oven drying to obtain rhizoma Dioscoreae. Selecting crude rhizoma Dioscoreae, soaking in clear water, slightly heating, covering with cotton quilt, keeping wet, kneading into cylinder, cutting two ends, sun drying, and polishing to obtain the final product. The main functional indications are as follows: to invigorate the spleen, tonify the lung, strengthen the kidney and replenish vital essence. It is indicated for diarrhea due to spleen deficiency, chronic dysentery, cough due to asthenia, diabetes, spermatorrhea, leukorrhagia, and frequent micturition. Tonify spleen and stomach, promote the production of body fluid and nourish lung, tonify kidney and astringe essence. Can be used for treating spleen deficiency, anorexia, chronic diarrhea, lung deficiency, cough, asthma, spermatorrhea, leukorrhagia, frequent micturition, and diabetes due to deficiency heat. The bran-parched rhizoma Dioscoreae has effects of invigorating spleen and invigorating stomach. Can be used for treating spleen deficiency, anorexia, diarrhea, loose stool, and leukorrhagia. (I) Ben Jing: mainly injures middle energizer, tonifies deficiency, removes pathogenic cold and heat, supplements middle energizer and strengthens strength, and can grow muscles and improve hearing and eyesight after long-term administration. ② Biyu (miscellaneous records): mainly treating head wind, dizziness, descending qi, stopping lumbago, treating asthenia, emaciation, tonifying five internal organs, removing dysphoria and heat, and strengthening key. ③ treatise on herb Property: it can be used for treating consumptive disease, cold wind, lumbago, palpitation, deficiency of heart-qi, asthenia, and asthenia. Fourthly, food therapy materia Medica: it is indicated for headache and helps yin. Fifth, Rihuazi Bencao: to help the five internal organs, strengthen tendons and bones, promote the growth of mind, induce tranquilization, and induce emission of essence and amnesia. Sixthly, Zhuzhenheng: the raw pounded plaster can dissipate swelling and hard toxin. Seventhly, the important essentials for exogenous febrile disease: tonify deficiency, clear deficiency heat. Eighthly, compendium: tonify kidney qi, strengthen spleen and stomach, stop diarrhea, resolve phlegm and moisten skin and hair.

The Corni fructus is dried mature pulp of Cornus officinalis Sieb. et Zucc. Is distributed in Shanxi, Jiangsu, Zhejiang, Anhui, Jiangxi, Shandong, Henan, Hunan, Sichuan, Shaanxi, Gansu, etc. Has the efficacies of tonifying liver and kidney, astringing and relieving depletion. It is commonly used for vertigo, tinnitus, soreness and pain of waist and knees, impotence, spermatorrhea, enuresis, frequent micturition, metrorrhagia, leukorrhagia, profuse sweating, exhaustion, internal heat, and diabetes.

Cortex moutan is dry root bark of Paeonia suffruticosa Andr. Produced in Anhui, Shandong, etc. Digging root in autumn, removing fine root, peeling root bark, and sun drying. Unprocessed or stir-baked. Modern researches show that paeonol and other glycosides have anti-inflammatory effect; the methanol extract of cortex moutan has platelet inhibiting effect; paeonol has central inhibitory effect on tranquilizing mind, lowering temperature, relieving fever, relieving pain, relieving spasm, etc., and has effects of resisting atherosclerosis, diuresis, and ulcer.

Radix Paeoniae alba is dried root of Paeonia lactiflora Pall of Ranunculaceae. Collected in summer and autumn, cleaned, removed head, tail and fine root, boiled in boiling water, peeled or boiled again, and dried in the sun. Has the functions of nourishing blood, regulating menstruation, astringing yin, arresting sweating, softening liver, relieving pain and suppressing liver yang. It is commonly used for blood deficiency and chlorosis, irregular menstruation, spontaneous perspiration, night sweat, hypochondriac pain, abdominal pain, limb spasm and pain, headache and vertigo.

Bulbus Fritillariae Cirrhosae is dried bulb of Bulbus Fritillariae Cirrhosae Fritil lararia cirrhosa D.Don, Fritil lararia unibracteata Hsiao et K.C.Hsia, Fritillaria przewalski Maxim, Fritillaria fusiformis Delavayi Franch, Fritillaria taipaiensis Taibai Taipaiensis P.Y.Li or Fritillaria unibracteata Hsiao et K.C.Hsiavar.wabuensis (S.Y.Tang et C.Yue) Z.D.Liu, S.Wanget S.C.Chen, of Liliaceae. According to different properties, the raw materials are called "Pingbei", "Qingbei", "furnace shell" and "cultivated product". Has effects of clearing heat, moistening lung, eliminating phlegm, relieving cough, resolving hard mass, and resolving carbuncle. Can be used for treating lung heat dry cough, dry cough with little phlegm, cough due to yin deficiency, bloody sputum, scrofula, acute mastitis, and pulmonary abscess.

The mint is a labiate plant, namely other dry whole plants in the same genus, mostly grows beside the mountain wetland river, and roots and stems transversely grow underground, and is an aromatic crop with special economic value. It is a sweating and antipyretic, and can be used for treating influenza, headache, conjunctival congestion, fever, sore throat, and gum swelling.

Charred fructus crataegi has effects of treating diarrhea, resolving food stagnation, promoting appetite, promoting blood circulation, removing blood stasis, preventing heatstroke, lowering blood pressure, etc. It is originated in sunny hillside or mountain shrub and is distributed in Jiangsu, Zhejiang, Yunnan, Sichuan and Guangxi provinces in China.

The parched fructus Hordei Germinatus is mainly used for treating indigestion, abdominal distention and pain, spleen deficiency, anorexia, milk sweat, stagnation, breast distending pain, and female hypogalactia. But is not suitable for lactating women.

The honey-fried licorice root is a round-like or oval slice, the surface is reddish brown or grayish brown, the honey-fried licorice root is slightly glossy, the section is yellow to dark yellow, the cambium ring is obvious, and the rays are radial. The honey-fried licorice decoction has the treatment effects of tonifying qi, nourishing yin, activating yang and recovering pulse.

The invention has the advantages that:

1. the invention aims at the deficiency of lung and spleen qi, often dry throat, but not desire to drink, cough, phlegm easy to expectorate, aversion to cold, hyperhidrosis, easy to catch cold, mental fatigue and hypodynamia, low voice, loose stool, light pharyngeal congestion, long course of disease and acute attack all the time. The syndrome of slight dryness, itching and pain in the throat, foreign body obstruction or phlegm adhesion, hyperhidrosis, susceptibility to sensation, lassitude and hypodynamia. Sometimes it is accompanied with kidney-yang deficiency manifested as soreness of waist and knees, clear and profuse urine, lassitude and cold limbs.

The traditional Chinese medicine composition is a traditional Chinese medicine composition for treating chronic pharyngitis, mainly tonifying lung and spleen, warming kidney and strengthening yang and guiding fire to origin, simultaneously reinforcing middle-jiao and strengthening qi, and can effectively solve the traditional Chinese medicine pathological mechanism of chronic pharyngitis patients with deficiency of kidney qi due to chronic diseases caused by deficiency of lung-spleen qi by adding the medicines for tonifying lung, tonifying spleen and tonifying qi and simultaneously warming kidney and strengthening yang and guiding fire to origin.

2. The invention optimizes the raw material medicines and the weight ratio thereof to achieve the best clinical curative effect. Research results show that the mixture ratio can improve clinical symptoms of chronic pharyngitis patients with lung-spleen qi deficiency.

3. The raw materials of the invention accord with the compatibility principle of 'monarch, minister, assistant and guide': radix astragali, rhizoma Atractylodis Macrocephalae, radix Saposhnikoviae, radix Ginseng, semen Nelumbinis, semen Coicis, fructus Amomi, and Poria are used for invigorating lung and spleen; cinnamon, prepared rehmannia root, Chinese yam and cornus officinalis are used as monarch drugs for warming the kidney and strengthening yang, and guiding fire to the origin, cortex moutan, white paeony root, bulbus fritillariae cirrhosae and mint are used as ministerial drugs for nourishing yin, clearing away the lung-heat and relieving sore throat, and fructus crataegi preparata, honey-fried licorice root and stomach are used as assistant drugs. The invention has strict formula and mild drug property, and can improve the compliance of people.

Detailed Description

The invention will be further illustrated with reference to specific embodiments. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that various changes and modifications can be made by one skilled in the art after reading the disclosure of the present invention, and equivalents fall within the scope of the invention defined by the appended claims.

EXAMPLE 1 Chinese medicinal composition 1

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 20 parts of astragalus membranaceus, 25 parts of bighead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 20 parts of ginseng, 15 parts of lotus seed pulp, 20 parts of semen coicis, 8 parts of fructus amomi, 30 parts of poria cocos, 8 parts of cinnamon, 20 parts of prepared rehmannia root, 20 parts of Chinese yam, 25 parts of cornus officinalis, 10 parts of cortex moutan, 16 parts of radix paeoniae alba, 8 parts of bulbus fritillariae cirrhosae, 16 parts of mint, 10 parts of scorched hawthorn fruit, 30 parts of fried malt and 8 parts of honey-fried licorice root.

EXAMPLE 2 Chinese medicinal composition (II)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 30 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 20 parts of divaricate saposhnikovia root, 10 parts of ginseng, 25 parts of lotus seed pulp, 10 parts of semen coicis, 12 parts of fructus amomi, 20 parts of poria cocos, 12 parts of cinnamon, 10 parts of prepared rehmannia root, 30 parts of Chinese yam, 15 parts of cornus officinalis, 20 parts of cortex moutan, 8 parts of radix paeoniae alba, 12 parts of bulbus fritillariae cirrhosae, 10 parts of mint, 16 parts of scorched hawthorn fruit, 20 parts of fried malt and 12 parts of honey-fried licorice root.

EXAMPLE 3 Chinese medicinal composition (III)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 25 parts of astragalus membranaceus, 20 parts of bighead atractylodes rhizome, 15 parts of divaricate saposhnikovia root, 15 parts of ginseng, 20 parts of lotus seed pulp, 15 parts of semen coicis, 10 parts of fructus amomi, 25 parts of poria cocos, 10 parts of cinnamon, 15 parts of prepared rehmannia root, 25 parts of Chinese yam, 20 parts of cornus officinalis, 15 parts of cortex moutan, 12 parts of radix paeoniae alba, 10 parts of bulbus fritillariae cirrhosae, 13 parts of mint, 13 parts of scorched hawthorn fruit, 25 parts of roasted malt and 10 parts of honey-fried licorice root.

Example 4 Chinese medicinal composition (IV)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 20 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 10 parts of ginseng, 15 parts of lotus seed pulp, 10 parts of semen coicis, 8 parts of fructus amomi, 20 parts of poria cocos, 8 parts of cinnamon, 10 parts of prepared rehmannia root, 20 parts of Chinese yam, 15 parts of cornus officinalis, 10 parts of cortex moutan, 8 parts of radix paeoniae alba, 8 parts of bulbus fritillariae cirrhosae, 10 parts of mint, 10 parts of scorched hawthorn fruit, 20 parts of fried malt and 8 parts of honey-fried licorice root.

EXAMPLE 5 Chinese medicinal composition (V)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 30 parts of astragalus membranaceus, 25 parts of bighead atractylodes rhizome, 20 parts of divaricate saposhnikovia root, 20 parts of ginseng, 25 parts of lotus seed pulp, 20 parts of semen coicis, 12 parts of fructus amomi, 30 parts of poria cocos, 12 parts of cinnamon, 20 parts of prepared rehmannia root, 30 parts of Chinese yam, 25 parts of cornus officinalis, 20 parts of cortex moutan, 16 parts of radix paeoniae alba, 12 parts of bulbus fritillariae cirrhosae, 16 parts of mint, 16 parts of scorched hawthorn fruit, 30 parts of fried malt and 12 parts of honey-fried licorice root.

EXAMPLE 6 Chinese medicinal composition (VI)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 20-30 parts of astragalus membranaceus, 15-25 parts of bighead atractylodes rhizome, 10-20 parts of divaricate saposhnikovia root, 10-20 parts of ginseng, 15-25 parts of lotus seed pulp, 10-20 parts of coix seed, 8-12 parts of fructus amomi, 20-30 parts of poria cocos, 8-12 parts of cinnamon, 10-20 parts of prepared rehmannia root, 20-30 parts of Chinese yam, 15-25 parts of cornus officinalis, 10-20 parts of cortex moutan, 8-16 parts of white paeony root, 8-12 parts of bulbus fritillariae cirrhosae, 10-16 parts of mint, 10-16 parts of scorched hawthorn fruit, 20-30 parts of fried malt and 8-12 parts of honey-fried licorice root.

EXAMPLE 7 Chinese medicinal composition (seven)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 20 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 10 parts of ginseng, 15 parts of lotus seed pulp, 10 parts of semen coicis, 8 parts of fructus amomi, 20 parts of poria cocos, 8 parts of cinnamon, 20 parts of prepared rehmannia root, 30 parts of Chinese yam, 25 parts of cornus officinalis, 20 parts of cortex moutan, 16 parts of radix paeoniae alba, 12 parts of bulbus fritillariae cirrhosae, 16 parts of mint, 16 parts of scorched hawthorn fruit, 30 parts of fried malt and 12 parts of honey-fried licorice root.

EXAMPLE 8 Chinese medicinal composition (eight)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 30 parts of astragalus membranaceus, 25 parts of bighead atractylodes rhizome, 20 parts of divaricate saposhnikovia root, 20 parts of ginseng, 25 parts of lotus seed pulp, 20 parts of semen coicis, 12 parts of fructus amomi, 30 parts of poria cocos, 12 parts of cinnamon, 10 parts of prepared rehmannia root, 20 parts of Chinese yam, 15 parts of cornus officinalis, 10 parts of cortex moutan, 8 parts of radix paeoniae alba, 8 parts of bulbus fritillariae cirrhosae, 10 parts of mint, 10 parts of scorched hawthorn fruit, 20 parts of fried malt and 8 parts of honey-fried licorice root.

EXAMPLE 9 Chinese medicinal composition (nine)

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 22 parts of astragalus membranaceus, 22 parts of bighead atractylodes rhizome, 18 parts of divaricate saposhnikovia root, 12 parts of ginseng, 17 parts of lotus seed pulp, 18 parts of coix seed, 8 parts of fructus amomi, 28 parts of poria cocos, 12 parts of cinnamon, 18 parts of prepared rehmannia root, 28 parts of Chinese yam, 18 parts of cornus officinalis, 18 parts of cortex moutan, 16 parts of radix paeoniae alba, 8 parts of bulbus fritillariae cirrhosae, 10 parts of mint, 14 parts of scorched hawthorn fruit, 28 parts of roasted malt and 12 parts of honey-fried licorice root.

Example 10 decoction

The preparation method comprises the following steps: taking the raw materials according to the weight part ratio of any one of embodiments 1-9, soaking in water for 1 hour, then decocting in water for 2 times, adding 10 times of water by weight of the raw materials each time, boiling and decocting for 50min for the first time, boiling and decocting for 40min for the second time, and combining the decoctions; and (4) finishing.

EXAMPLE 11 granules

The preparation method comprises the following steps: taking the raw materials according to the weight part ratio of any one of embodiments 1-9, soaking in water for 1 hour, then decocting in water for 2 times, adding 10 times of water by weight of the raw materials each time, boiling and decocting for 50min for the first time, boiling and decocting for 40min for the second time, and combining the decoctions; filtering, concentrating the filtrate, cooling to room temperature, and concentrating the supernatant into fluid extract. Mixing the fluid extract, dextrin and other medicinal adjuvants, and making into granule.

EXAMPLE 12 tablet/Capsule

The preparation method comprises the following steps: taking the raw materials according to the weight part ratio of any one of the embodiments 1-9, soaking for 1 hour, adding water, decocting for 2 times, adding 10 times of water by weight of the raw materials each time, boiling and decocting for 50min for the first time, boiling and decocting for 40min for the second time, and combining the decoctions; filtering, concentrating the filtrate, cooling to room temperature, concentrating the supernatant to obtain soft extract, adding adjuvants, vacuum drying, pulverizing, granulating, and making into tablet or capsule.

Example 13

The beneficial effects of the present invention are illustrated below in connection with clinical use data:

diagnostic criteria: referring to the 'standard of the Chinese medicine industry of the people's republic of China 'standard of curative effect for diagnosing traditional Chinese medicine disease symptoms-standard of curative effect for diagnosing otolaryngological disease symptoms', the main symptoms are dry throat, throat itching, burning heat, slight pain and foreign body sensation of throat; the main signs are chronic congestion of pharyngeal mucosa, or atrophy, hypertrophy of pharyngeal lateral cord, and hyperplasia of pharyngeal posterior lymph follicles; the course of the disease is as follows: more than 2 months; the medical history: there may be a history of repeated attacks of acute pharyngitis, or a history of addiction to cigarettes, wines, spicy foods, or a history of long-term smoke and harmful gas stimulation. And combines the syndrome differentiation of the traditional Chinese medicine: often, the throat is dry but not drunk, cough with phlegm is easy to expectorate, aversion to cold in normal times, hyperhidrosis, susceptibility to cold, tiredness and hypodynamia, low voice, loose stool, light congestion of the throat, long course of disease and frequent acute attack. The throat is slightly dry, slightly itchy and slightly painful, and has foreign body obstruction or phlegm adhesion, which is accompanied with hyperhidrosis, susceptibility to sensation, lassitude and hypodynamia, and sometimes accompanied with soreness of waist and knees, clear and long urine, lassitude and cold limbs. The traditional Chinese medicine composition has the symptoms, and can be used for diagnosing chronic pharyngitis with the lung-spleen qi deficiency type and chronic pharyngitis with kidney yang deficiency type by combining local signs. The number of patients was 50, 26 men and 24 women.

The taking method comprises the following steps: the preparation of the invention in example 1 is taken every day, and can be taken before and after meals, and seven days are a treatment course.

The judgment standard of the curative effect is as follows: the effect is shown: pharyngeal symptoms disappeared and the test was normal. The method has the following advantages: pharyngeal symptoms and signs are significantly reduced. And (4) invalidation: no obvious change in symptoms and signs. The chronic pharyngitis can be divided into three categories of obvious effect, effective effect and ineffective effect according to the related conditions of the chronic pharyngitis.

In 50 cases, after the traditional Chinese medicine is taken, 12 cases of the traditional Chinese medicine are effective, 32 cases of the traditional Chinese medicine are effective, 6 cases of the traditional Chinese medicine are ineffective, the effective rate is 88%, and no toxic or side effect occurs in the treatment period.

Typical cases are: the medicine is used for treating chronic pharyngitis caused by deficiency of lung and spleen qi and chronic pharyngitis caused by insufficiency of kidney yang, wherein the throat dryness disappears after one month, the cough disappears occasionally, the cough disappears after four months, the cough is healed, and the cough does not relapse after two years of return visit.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. The traditional Chinese medicine composition for treating chronic pharyngitis is characterized by being prepared from the following raw material medicines in parts by weight: 20-30 parts of astragalus membranaceus, 15-25 parts of bighead atractylodes rhizome, 10-20 parts of divaricate saposhnikovia root, 10-20 parts of ginseng, 15-25 parts of lotus seed pulp, 10-20 parts of coix seed, 8-12 parts of fructus amomi, 20-30 parts of poria cocos, 8-12 parts of cinnamon, 10-20 parts of prepared rehmannia root, 20-30 parts of Chinese yam, 15-25 parts of cornus officinalis, 10-20 parts of cortex moutan, 8-16 parts of white paeony root, 8-12 parts of bulbus fritillariae cirrhosae, 10-16 parts of mint, 10-16 parts of scorched hawthorn fruit, 20-30 parts of fried malt and 8-12 parts of honey-fried licorice root.

2. The traditional Chinese medicine composition according to claim 1, which is prepared from the following raw materials in parts by weight: 25-30 parts of astragalus membranaceus, 20-25 parts of bighead atractylodes rhizome, 15-20 parts of divaricate saposhnikovia root, 15-20 parts of ginseng, 20-25 parts of lotus seed pulp, 15-20 parts of coix seed, 10-12 parts of fructus amomi, 25-30 parts of poria cocos, 10-12 parts of cinnamon, 15-20 parts of prepared rehmannia root, 25-30 parts of Chinese yam, 20-25 parts of cornus officinalis, 15-20 parts of cortex moutan, 12-16 parts of white paeony root, 10-12 parts of bulbus fritillariae cirrhosae, 12-16 parts of mint, 12-16 parts of scorched hawthorn fruit, 25-30 parts of fried malt and 10-12 parts of honey-fried licorice root.

3. The Chinese medicinal composition according to any one of claims 1 to 2, which is prepared into a clinically acceptable pharmaceutical preparation according to a conventional Chinese medicinal preparation method.

4. The traditional Chinese medicine composition of claim 3, wherein the pharmaceutical preparation is granules, powder, capsules, tablets, decoction or oral liquid.

5. Use of the Chinese medicinal composition of any one of claims 1-2 in the preparation of a medicament for treating chronic pharyngitis.

6. The use of claim 5, wherein the chronic pharyngitis is chronic pharyngitis due to deficiency of lung and spleen qi.

7. The use of claim 6, wherein the chronic pharyngitis is chronic pharyngitis due to deficiency of both lung and spleen qi and kidney yang deficiency.

8. A medicament for treating chronic pharyngitis, which is characterized in that the medicament is prepared from the traditional Chinese medicine composition as claimed in any one of claims 1-2.

9. The medicament of claim 8, further comprising a pharmaceutically acceptable adjuvant.

10. The method for preparing a medicament according to claim 8, comprising the steps of:

(1) taking raw material medicines: soaking radix astragali, Atractylodis rhizoma, radix Saposhnikoviae, Ginseng radix, semen Nelumbinis, Coicis semen, fructus Amomi, Poria, cortex Cinnamomi, radix rehmanniae Preparata, rhizoma Dioscoreae, Corni fructus, cortex moutan, radix Paeoniae alba, Bulbus Fritillariae Cirrhosae, herba Menthae, fructus crataegi preparata, fructus Hordei Germinatus preparata, and radix Glycyrrhizae Preparata in water for 1 hr;

(2) decocting in water for 2 times, adding 10 times of water each time, boiling and decocting for 50min for the first time and 40min for the second time, and mixing decoctions;

(3) adding pharmaceutically acceptable pharmaceutical adjuvants according to conventional process, and making into clinically acceptable granule, powder, capsule, tablet, decoction or oral liquid.