CN104721634A - Chinese herbal preparation for herpangina and preparation method of Chinese herbal preparation for herpangina - Google Patents

Abstract

The invention discloses a Chinese herbal preparation for herpangina. The Chinese herbal preparation for herpangina is composed of dried rehmannia roots, prepared rehmannia roots, fructus forsythiae, honeysuckles, lophatherum gracile, akebiaquinata, Sichuan dendrobium, subprostrate sophora, folium isatidis, wild chrysanthemum, cortex phellodendri chinensis, scutellaria baicalensis, coptis chinensis, gypsum, rhizoma anemarrhenae, aloes, radix asparagi, radix ophiopogonis, radix scrophulariae, radix paeoniae alba, radix adenophorae, radix trichosanthis, indigo naturalis, calamitas urinae hominis and raw liquorice. According to different characteristics of the traditional Chinese medicines, the raw materials are cleaned and chopped for pretreatment and prepared proportionally to make the Chinese herbal preparation for herpangina according to a special method. The Chinese herbal preparation for herpangina has the functions of wind dispelling, heat clearing, detoxifying, sore throat relieving and swelling and pain relieving. The Chinese herbal preparation for herpangina and the preparation method are unique, and the Chinese herbal preparation for herpangina has the advantages of remarkable treatment effects, low price, avoidance of adverse reactions and toxic and side effects and broad market application prospect.

Description

A kind of Chinese medicine preparation for herpangina and preparation method

Technical field

The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for herpangina, the invention still further relates to the preparation method of this Chinese medicine preparation.

Background technology

Herpangina is a kind of acute infective, febrile disease, and be by many A group Coxsackie viruss, also have once in a while caused by other enterovirus, its feature is herpetic ulcer mucosal injury.Herpangina has fashion trend, is common in infant, and Clinical symptoms is suddenly play high heat with throat pain, headache, anorexia, and often has neck, abdomen and limbs pain.Often there is vomiting baby and faint from fear, in onset 2 days there is (diameter 1 ~ 2mm) canescence herpes that minority (seldom more than 12) is little in oral mucosa, around around with blush, be more common in tonsil front portion, but also can be positioned at soft palate, tonsil, uvula, tongue etc., in afterwards 24 hours, blister ulceration becomes fester, diameter, generally at below 5mm, heals in 1 ~ 5 day.Complication is rare: symptom disappears in general 7 days.Can produce lasting immunity after infection, but its alloytype virus or other enterovirus also may cause and again fall ill.Diagnosis can be made according to symptom and characteristic oral lesion.Differential Diagnosis comprises herpetic stomatitis (feature is all can fall ill any season, presents larger, continues ulcer more of a specified duration), recurrent aphtha and Bednar aphtha (seldom betiding pharyngeal, general without General Symptoms).COxsackie A group 10 type virus also can cause similar pathological changes (lymph node pharyngitis), but pars oralis pharyngis infringement is outstanding, presents white to yellow brief summary.Treatment is anti symptom treatment.

The main Reduning injection treatment of doctor trained in Western medicine AM western medical treatment method clinically at present, but current treatment herpangina scheme curative effect is not high, brings larger misery and inconvenience to the life of patient.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation being used for the treatment of herpangina, it is remarkable, cheap that this Chinese medicine preparation has therapeutic effect for treatment herpangina, has no adverse reaction and the feature of secondary toxic action.

Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out to be used for the treatment of the new formula of the Chinese medicine preparation of herpangina repeatedly.It is remarkable that the present invention has therapeutic effect, cheap, has no adverse reaction and the feature of secondary toxic action.

The effect of Chinese medicine of the present invention:

Wherein:

Radix Rehmanniae: be the fresh or dried root of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch..Radix Rehmanniae: sweet, cold.GUIXIN, liver, kidney channel.Effect: clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.

Radix Rehmanniae Preparata: be the Preparation process product of Radix Rehmanniae.Nature and flavor: sweet, tepor.Return liver, kidney channel.Function cures mainly: nourishing YIN and supplementing blood, and beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.Record in " pearl sac ": enrich blood greatly empty not enough, promoting blood circulation, physical strength profiting.

Fructus Forsythiae: be the dry fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.Nature and flavor: bitter, are slightly cold.Return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.Record in " herbal classic ": main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat.

Flos Lonicerae: the flower that dry flower or band for caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb., Flos Lonicerae Lonicera hypoglauca Miq., Flos Lonicerae (hair calyx Radix Ophiopogonis) Lonicera confusa DC. or hair style Radix Ophiopogonis Lonicera dasystyla Rehd. are just opened.Nature and flavor: sweet, cold.Return lung, the heart, stomach warp.Effect: heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.Record in " the SHENGCAO property of medicine is standby to be wanted ": energy eliminating carbuncle cellulitis furunculosis, dysentery relieving disease, washes chancre, peeling skin heat in blood.

Herba Lophatheri: be the dry stem and leaf of grass Herba Lophatheri Lophatherum gracile Brongn..Nature and flavor: sweet, light, cold.GUIXIN, stomach, small intestine meridian.Effect: clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.Record in " the SHENGCAO property of medicine is standby to be wanted ": expectorant is quenched the thirst, except part of the body cavity above the diaphragm housing the heart and lungs fire, bright eyes, diuresis, controls nebulousurine, brings down a fever, loose hemorrhoid poison.

Caulis Akebiae: be the woody stems of plants of Lardizabalaceae Caulis Akebiae or threeleaf akebia, Caulis Akebiae.Nature and flavor: bitter; Cold in nature.GUIXIN; Spleen; Kidney; Small intestinal; Urinary bladder channel.Effect: clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Main red urine is red; Stranguria with turbid discharge; Edema; Irritable feverish sensation in the chest; Larynx larynx pain; Aphtha of the mouth and tongue; Rheumatic arthralgia; Galactostasis; Amenorrhea; Dysmenorrhea.Record in " herbal classic ": " main going dislikes worm, and except taste cold and heat, tonneau nine orifices blood vessels joint, makes us not forgetting.

Sichuan Herba Dendrobii: be Sichuan orchid dendrobium loddigesii Rolfe Dendrobium loddigesii Rolfe., Herba Dendrobii oculati Dendrobium fimbriatum Hook. var. oculatum Hook., the fresh or dry stem of HERBA DENDROBII Dendrobium chrysanthum Wall., Herba Dendrobii Dendrobium candidum Wall. ex Lindl. or Dendrobium nobile Dendrobium nobile Lindl..Nature and flavor: sweet, are slightly cold.Return stomach, kidney channel.Function cures mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.Record in " book on Chinese herbal medicine is new again ": reason gastric qi, clearing stomach fire, removes excessive thirst in the heart, treats kidney channel deficiency-heat, arresting convulsion of calming the nerves, and separate night sweat, can fall apart summer-heat.

Radix Sophorae Tonkinensis: be the dry root and rhizome of leguminous plant Sophora tonkinensis Gagnep. Sophora tonkinensis Gapnep..Nature and flavor: bitter, cold; Poisonous.Attach to the lung and stomach meridians.Effect: heat-clearing and toxic substances removing, detumescence sore-throat relieving.Pent up for fire-toxin, laryngopharynx swelling and pain, gingivitis.Record in " Kaibao Bencao ": all poison of drug of principal solution, pain relieving.Disappear pyogenic infections from tumour or sore, and acute jaundice fever and cough, kills small worm.

Folium Isatidis: be the dried leaves of cruciferae isatis Isatis indigotica Fort..Nature and flavor: bitter, cold.GUIXIN, stomach warp.Effect: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Join the army for pathogenic warmth, unconsciousness due to high fever, sends out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.Record in " book on Chinese herbal medicine just ": control pestilence pyretic toxicity and go mad, wind heat macule, carbuncle and ulcer swells and ache, relieving thirst and restlessness, only epistaxis, haematemesis, kill infantile malnutrition erosion, incised wound curare.Allly to hold concurrently malicious person with heat, all LANYE should smash juice and use it.

Flos Chrysanthemi Indici: be the dry capitulum of feverfew chrysanthemum Chrysanthemum morifolium Ramat..Nature and flavor: sweet, bitter, are slightly cold.Return lung, Liver Channel.Function cures mainly: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.Record in " herbal classic ": main all dizziness due to wind, to swell and ache, order for de-, lacrimation, the dead flesh of skin, aversion to wind arthralgia chiefly caused by damp pathogen, sharp vim and vigour.

Cortex Phellodendri: be the dry bark of rutaceae wampee Phellodendron chinense Schneid. or Cortex Phellodendri Phellodendron amurense Rupr..Nature and flavor: bitter, cold.Return kidney, urinary bladder channel.Effect: heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.Record in supplement to the Herbal: " main herpes simplex bleb rises, worm skin ulcer, dysentery, and hematochezia, kills moth; Decoction, master quenches one's thirst." record in " medicine origin ": " curing mainly secret formula " cloud, rush down bladder dragon fire, profit knot urine, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels damp-edema, dysentery foreknowledge blood, subumbilical pain, mends deficiency of kidney-YIN.

Radix Scutellariae: be the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.Nature and flavor: bitter, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Effect: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.Record in " herbal classic ": main all hot jaundice, intestinal Bleach, lets out profit, relieves oedema or abdominal distension through diuresis or purgation, and hematochezia closes, (controlling) malignant boil, and cellulitis is lost, acute scleritis.

Rhizoma Coptidis: be the dry rhizome of ranunculaceae plant Rhizoma Coptidis Coptis chinensis Franch., Coptis deltoidea C.Y.Cheng et Hsiao Coptis deltoidea C. Y. Cheng et Hsiao or Coptis Teeta Wall Coptis teeta Wall..Nature and flavor: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.Record in essentials of Matea Medica: control carbuncle skin ulcer scabies, alcoholism, fetal toxicosis.Except infantile malnutrition, kill ascarid.

Gypsum Fibrosum: be Sulfates mineral anhydrite race Gypsum Fibrosum, main containing hydrous calcium sulfate (CaSO42H2O).Nature and flavor: sweet, pungent, Great Cold.Attach to the lung and stomach meridians.Effect: clearing away heat-fire, relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.Record in " not Lu ": except seasonal epidemic pathogens headache fever of the body, three burnt large heat, skin heat, heat of the diaphragm in the intestines and stomach, expelling pathogenic factors from muscles by diaphoresis, restlessness accompanied by ascending of QI of only quenching one's thirst, abdominal distention is panted breath cruelly, pharynx heat.Also can do to bathe soup.

The Rhizoma Anemarrhenae: be the dry rhizome of liliaceous plant Rhizoma Anemarrhenae Anemarrhena asphodeloides Bunge..Nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.Effect; Clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.Record in " not Lu ": cold chronic malaria dysphoria with smothery sensation of curing the wound, the lower pathogen of the side of body, the disease due to obstruction of QI of middle-JIAO is disliked and subcutaneous ulcer in wind antiperspirant.

Aloe: for liliaceous plant Aloe vulgaris Aloe barbadensis Miller, Aloe ferox Miller Aloe ferox Miller or other belong to the dry product of concentrated juice of kindred plant leaf together.Nature and flavor: bitter, cold.Return liver, stomach, large intestine channel.Effect: removing heat from the liver, relieving constipation.For constipation, infantile malnutrition, infantile convulsion; External treatment exudative dermatitis.Record in " property of medicine opinion ": kill children's's infantile malnutrition ascarid.Head boil of malnutrition infant is killed in main nasal insufflation, except rhinocnesmus.

Radix Asparagi: be the dried root of liliaceous plant Radix Asparagi Asparagus cochinchinensis (Lour.) Merr..Nature and flavor: sweet, bitter, cold.Return lung, kidney channel.Function cures mainly: nourishing YIN to relieve dryness, and lung heat clearing is promoted the production of body fluid.For dryness of the lung dry cough, pertussis expectorant sticks, dry throat and mouth, dryness of the intestine constipation.

Radix Ophiopogonis: be the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (Thunb.) Ker-Gawl..Nature and flavor: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.Function cures mainly: YIN nourishing and the production of body fluid promoting, and lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.

Radix Scrophulariae: be the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl..Nature and flavor: sweet, bitter, salty, are slightly cold.Return lung, stomach, kidney channel.Effect: removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.Record in " Japan hanako materia medica ": control wind syndrome of head pyretic toxicity urticaria, tonify deficiency strains, and the heart is frightened irritated, and bad weary hectic fever due to YIN-deficiency passes corpse pathogen, only forgetful, detumescence poison.

The Radix Paeoniae Alba: be the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: bitter, sour, are slightly cold.Return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.Record in " herbal classic ": main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.

Radix Adenophorae (Radix Glehniae): be campanulaceae Lady bell plant four leaf Radix Adenophorae (Radix Glehniae) Adenophora tetraphylla (Thunb.) Fisch. [A. berticillata (Pall.) Fisch.], Folium Pruni Radix Adenophorae (Radix Glehniae) A. axilliflora Borb [A. stricta Miq.] or its congener, be used as medicine with root.Nature and flavor: sweet are cool.Return lung; Stomach warp.Effect: clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, cough up phlegm yellow thick.

Radix Trichosanthis: be the dry root of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms Trichosan-thes rosthornii Herms.Nature and flavor: sweet, micro-hardship, is slightly cold.Attach to the lung and stomach meridians.Effect: clearing away heat and promoting production of body fluid, detumescence and apocenosis.For calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.Record in " Japan hanako materia medica ": logical small intestinal, evacuation of pus, detumescence poison, granulation promoting is put on flesh, and disappears and flutters damage blood stasis.Disease when controlling fanatical, acute mastitis, carbuncle on the back, hemorrhoid complicated by anal fistula furuncle.

Indigo Naturalis: for the leaf of acanthaceous vegetable acanthaceous indigo Baphicacanthus cusia (Nees) Bremek., polygonaceae plant polygonum tinctorium ait. Polygonum tinctorium Ait. or cruciferae isatis Isatis indigotica Fort. or stem and leaf are through processing obtained dried powder or agglomerate.Nature and flavor: salty, cold.Return Liver Channel.Effect: heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.For maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared.Record in " Kaibao Bencao ": all poison of drug of principal solution, infantile pyretic diseases, infantile convulsion generates heat, pestilent headache cold and heat, decocts water and grinds and take it.Also rub deposited herpes simplex, dislike the poison such as swollen, incised wound, hematochezia, Serpentis dog.

Calamitas urinae hominis: for condensing in thin slice or the block sheet of the canescence amorphism in wooden pail for urine or urine cylinder, clean dry forms.Nature and flavor: salty, cold.Enter liver, three burnt, urinary bladder channels.Effect: heat-clearing and toxic substances removing, hemostasis by removing blood stasis.For laryngopharynx swelling and pain, ulcerative gingivitis aphtha, the diseases such as spitting of blood, epistaxis.Record in " detailed outline ": pathogenic fire reducing repercussive blood, control the raw skin ulcer of throat ability to speak, infantile malnutrition is hidden, bleeding from all orifices, skin hematohidrosis.

Radix Glycyrrhizae: be the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Record in " illustrated handbook planted by middle traditional Chinese medicines ": control peptic ulcer and jaundice.

Side's solution of the present invention is: side in Flos Lonicerae sweet in the mouth cold in nature, enter lung meridian, Fructus Forsythiae bitter in the mouth is cold in nature, two medicine wind and heat dispersing, resolving toxin and disinhibiting the throat; Folium Isatidis bitter in the mouth is cold in nature, returns lung meridian, is usually used in pharyngeal swelling, sore throat, and Radix Scutellariae, Rhizoma Coptidis, Indigo Naturalis, calamitas urinae hominis, bitter in the mouth are cold in nature, and Radix Glycyrrhizae sweet in the mouth is put down, and Radix Scutellariae enters lung meridian, and heat-clearing and toxic substances removing power is strong, is principal agent altogether; Radix Sophorae Tonkinensis resolving toxin and disinhibiting the throat is the key medicine for the treatment of bottleneck throat pain; Gypsum Fibrosum, Cortex Phellodendri, Rhizoma Anemarrhenae clearing heat in QI system are evil, Radix Scrophulariae, Radix Ophiopogonis Yin and detoxification sore-throat relieving, Radix Rehmanniae Preparata sweet in the mouth is warm in nature, clear interior-heat, is ministerial drug altogether; Sichuan Herba Dendrobii, variola mealiness sugariness are bitter, clearing away heat and promoting production of body fluid, Radix Adenophorae (Radix Glehniae), Radix Scrophulariae clearing away heat and nourishing YIN, and Radix Rehmanniae clearing away heat and cooling blood promotes the production of body fluid, and Radix Paeoniae Alba yin nourishing is stimulated the menstrual flow, and Flos Chrysanthemi Indici, sky winter habit sugariness are bitter, and YIN nourishing and the production of body fluid promoting, Aloe heat-clearing and toxic substances removing, Herba Lophatheri, Caulis Akebiae clearing away heat and promoting diuresis are adjuvant drug altogether.The all medicines of this side share, and the monarch and his subjects pull together, there is depressed liver-energy dispersing and QI regulating, stimulate the menstrual flow relieve the pain, YIN nourishing of invigorating blood circulation, effect of right supporting anticancer, effectively can treat herpangina.

Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Rehmanniae 13-17g, Radix Rehmanniae Preparata 13-17g, Fructus Forsythiae 13-17g, Flos Lonicerae 10-14g, Herba Lophatheri 10-14g, Caulis Akebiae 7-11g, Sichuan Herba Dendrobii 16-20g, Radix Sophorae Tonkinensis 8-12g, Folium Isatidis 13-17g, Flos Chrysanthemi Indici 7-11g, Cortex Phellodendri 10-14g, Radix Scutellariae 10-14g, Rhizoma Coptidis 4-8g, Gypsum Fibrosum 22-26g, Rhizoma Anemarrhenae 10-14g, Aloe 8-12g, Radix Asparagi 10-14g, Radix Ophiopogonis 10-14g, Radix Scrophulariae 13-17g, Radix Paeoniae Alba 13-17g, Radix Adenophorae (Radix Glehniae) 13-17g, Radix Trichosanthis 16-20g, Indigo Naturalis 8-12g, calamitas urinae hominis 7-11g, Radix Glycyrrhizae 4-8g.

Wherein be preferably: Radix Rehmanniae 15g, Radix Rehmanniae Preparata 15 g, Fructus Forsythiae 15 g, Flos Lonicerae 12 g, Herba Lophatheri 12 g, Caulis Akebiae 9 g, Sichuan Herba Dendrobii 18 g, Radix Sophorae Tonkinensis 10 g, Folium Isatidis 15 g, Flos Chrysanthemi Indici 9 g, Cortex Phellodendri 12 g, Radix Scutellariae 12 g, Rhizoma Coptidis 6 g, Gypsum Fibrosum 24 g, the Rhizoma Anemarrhenae 12 g, Aloe 10 g, Radix Asparagi 12 g, Radix Ophiopogonis 12 g, Radix Scrophulariae 15 g, the Radix Paeoniae Alba 15 g, Radix Adenophorae (Radix Glehniae) 15 g, Radix Trichosanthis 18 g, Indigo Naturalis 10g, calamitas urinae hominis 9g, Radix Glycyrrhizae 6 g.

A kind of preparation method of the Chinese medicine preparation for herpangina is as follows:

Step one: by weight of the present invention, gets Radix Rehmanniae Preparata and pulverizes ground 100 mesh sieves, for subsequent use; Get Aloe, smash 100 mesh sieves to pieces, for subsequent use; Get calamitas urinae hominis, smash 160 mesh sieves to pieces, for subsequent use; Get Indigo Naturalis, smash 160 mesh sieves to pieces, for subsequent use;

Step 2: by weight proportion of the present invention, get Radix Rehmanniae, Fructus Forsythiae, Flos Lonicerae, Herba Lophatheri, Caulis Akebiae, Sichuan Herba Dendrobii, Radix Sophorae Tonkinensis, Folium Isatidis, Flos Chrysanthemi Indici, Cortex Phellodendri, Radix Scutellariae, Rhizoma Coptidis, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Radix Asparagi, Radix Ophiopogonis, Radix Scrophulariae, the Radix Paeoniae Alba, Radix Adenophorae (Radix Glehniae), Radix Trichosanthis, Radix Glycyrrhizae removing impurity, clean, run through, drying, for subsequent use;

Step 3: by weight proportion of the present invention, is placed in marmite by step 2 Radix Adenophorae (Radix Glehniae), Radix Scrophulariae, adds the water that triploid is long-pending, slow fire infusion 15 ~ 20 minutes, and filter, infusion three times repeatedly, merging filtrate, discards filtering residue, for subsequent use;

Step 4: by weight proportion of the present invention, step 2 Chinese crude drug Radix Rehmanniae, Caulis Akebiae, Sichuan Herba Dendrobii, Radix Sophorae Tonkinensis, Cortex Phellodendri, Radix Scutellariae, Rhizoma Coptidis, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Radix Asparagi, Radix Ophiopogonis, the Radix Paeoniae Alba, Radix Trichosanthis, Radix Glycyrrhizae medical material are placed in marmite, add the water of 4 times of volumes, intense fire infusion 10 ~ 15 minutes, fiery infusion of larding speech with literary allusions is filtered for 20 ~ 30 minutes, add the water of 2 times of volumes again, Fructus Forsythiae, Flos Lonicerae, Herba Lophatheri, Folium Isatidis, Flos Chrysanthemi Indici are dropped in marmite, slow fire infusion 20 ~ 30 minutes, infusion merges gained filtrate three times repeatedly, discard filtering residue, for subsequent use;

Step 5: powder mixing in combining step three and step 4 gained filtrate and step one, stirs evenly, both Chinese medicine decoction of the present invention.

Using method of the present invention: get decoction decoction being taken warmly after meal, every day 2 times.It within 3 days, is a course for the treatment of.

Medicine of the present invention has wind and heat dispersing, resolving toxin and disinhibiting the throat, the effect of reducing swelling and alleviating pain, and effective, cheap, have no side effect, easy to use, alleviate the slight illness of patient, add up according to clinical 240 routine patient view, use medicine of the present invention the total effective rate course for the treatment of 82.5%, two the total effective rate course for the treatment of 95%.

Detailed description of the invention

Embodiment one: Radix Rehmanniae 15g, Radix Rehmanniae Preparata 15 g, Fructus Forsythiae 15 g, Flos Lonicerae 12 g, Herba Lophatheri 12 g, Caulis Akebiae 9 g, Sichuan Herba Dendrobii 18 g, Radix Sophorae Tonkinensis 10 g, Folium Isatidis 15 g, Flos Chrysanthemi Indici 9 g, Cortex Phellodendri 12 g, Radix Scutellariae 12 g, Rhizoma Coptidis 6 g, Gypsum Fibrosum 24 g, the Rhizoma Anemarrhenae 12 g, Aloe 10 g, Radix Asparagi 12 g, Radix Ophiopogonis 12 g, Radix Scrophulariae 15 g, the Radix Paeoniae Alba 15 g, Radix Adenophorae (Radix Glehniae) 15 g, Radix Trichosanthis 18 g, Indigo Naturalis 10g, calamitas urinae hominis 9g, Radix Glycyrrhizae 6 g.

Embodiment two: Radix Rehmanniae 16g, Radix Rehmanniae Preparata 14 g, Fructus Forsythiae 16g, Flos Lonicerae 13 g, Herba Lophatheri 13g, Caulis Akebiae 9 g, Sichuan Herba Dendrobii 18 g, Radix Sophorae Tonkinensis 10 g, Folium Isatidis 15 g, Flos Chrysanthemi Indici 9 g, Cortex Phellodendri 13g, Radix Scutellariae 12 g, Rhizoma Coptidis 6 g, Gypsum Fibrosum 24 g, the Rhizoma Anemarrhenae 12 g, Aloe 11 g, Radix Asparagi 12 g, Radix Ophiopogonis 12g, Radix Scrophulariae 15 g, the Radix Paeoniae Alba 15 g, Radix Adenophorae (Radix Glehniae) 15 g, Radix Trichosanthis 18 g, Indigo Naturalis 9g, calamitas urinae hominis 10g, Radix Glycyrrhizae 7 g.

Embodiment three: Radix Rehmanniae 16g, Radix Rehmanniae Preparata 16g, Fructus Forsythiae 15 g, Flos Lonicerae 12 g, Herba Lophatheri 11 g, Caulis Akebiae 10g, Sichuan Herba Dendrobii 18 g, Radix Sophorae Tonkinensis 10 g, Folium Isatidis 15 g, Flos Chrysanthemi Indici 10 g, Cortex Phellodendri 12 g, Radix Scutellariae 12 g, Rhizoma Coptidis 7g, Gypsum Fibrosum 25g, the Rhizoma Anemarrhenae 12 g, Aloe 10 g, Radix Asparagi 13 g, Radix Ophiopogonis 11 g, Radix Scrophulariae 16 g, the Radix Paeoniae Alba 16 g, Radix Adenophorae (Radix Glehniae) 15 g, Radix Trichosanthis 19 g, Indigo Naturalis 11g, calamitas urinae hominis 10g, Radix Glycyrrhizae 7 g.

Here is the clinical statistics data that patient uses medicine of the present invention:

One, physical data

240 routine infant Pediatric Clinic cases, according to the Standards of Chinese Medical Syndrome Differentiation of Western medicine diagnose standard and external wind heat syndrome, simultaneously except systemic diseases such as unfaithful intention, brain, liver, kidney, blood and severe malnutritions, be diagnosed as herpangina, and the course of disease is all within 2d, be divided into treatment group (I group) and matched group (II group) at random: I group of 96 example, wherein, man 57 example, female 39 example, 9 months ~ 12 years old age, average (5.2 ± 1.5) year, two groups of equal not statistically significants of comparing difference (P>0.05).

Two, Therapeutic Method:

1, observation group is according to Medications Example one of the present invention, weighting raw materials (daily dose), and by the treatment of invention implementation method, getting decoction warm, one day secondary, 3rd is a course for the treatment of.

2, matched group gives Reduning injection, and dosage is 0.5mL/(kg.d), add 0.9% sodium chloride solution 100mL, intravenous drip, 3d is 1 course for the treatment of.

Three, efficacy assessment standard:

1, cure: after treatment 3d, temperature recovery is normal, clinical symptom disappearance;

2, take a turn for the better: after treatment 3d, body temperature recovers normal substantially, and clinical symptoms disappears substantially;

3, invalid: not reach effective standard after treatment or the state of an illness comparatively before increases the weight of.

Four, therapeutic outcome statistics:

Matched group result is added up

Use the Comparison of therapeutic situation of this Chinese medicine preparation two groups of patients, two courses for the treatment of

Wherein: total effective rate=cure rate+improvement rate

Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness on treatment herpangina, effectively can improve the cure rate for the treatment of, Be very effective, cycle is short, without any side effects, has wide market application foreground.

Model case and curative effect:

Case one, patient Wang, man, 6 years old, people from Qingdao City.First visit on January 18 in 2012.Symptoms: hurried heating, continues high heat, tells pharyngalgia, when swallowing more so, does not have the symptoms such as cough, rhinorrhea.This symptom is herpangina.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, after a course for the treatment of of treatment, effect is very good, and after two courses for the treatment of, clinical symptoms disappears completely.

Case two, patient Lee, female, 4 years old, people from Weifang, Shandong.Carry out here treatment on May 14th, 2011.Symptoms: hurried heating, repeatedly high heat, dysphoria, refusing to eat, sialorrhea, vomiting etc.There is no the symptoms such as cough, rhinorrhea.This symptom is herpangina.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, after a course for the treatment of of treatment, effect is very good, and thoroughly cure after two courses for the treatment of, clinical symptoms disappears completely.

Claims (4)

1. the Chinese medicine preparation for herpangina, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Rehmanniae 13-17g, Radix Rehmanniae Preparata 13-17g, Fructus Forsythiae 13-17g, Flos Lonicerae 10-14g, Herba Lophatheri 10-14g, Caulis Akebiae 7-11g, Sichuan Herba Dendrobii 16-20g, Radix Sophorae Tonkinensis 8-12g, Folium Isatidis 13-17g, Flos Chrysanthemi Indici 7-11g, Cortex Phellodendri 10-14g, Radix Scutellariae 10-14g, Rhizoma Coptidis 4-8g, Gypsum Fibrosum 22-26g, Rhizoma Anemarrhenae 10-14g, Aloe 8-12g, Radix Asparagi 10-14g, Radix Ophiopogonis 10-14g, Radix Scrophulariae 13-17g, Radix Paeoniae Alba 13-17g, Radix Adenophorae (Radix Glehniae) 13-17g, Radix Trichosanthis 16-20g, Indigo Naturalis 8-12g, calamitas urinae hominis 7-11g, Radix Glycyrrhizae 4-8g.

2. a kind of Chinese medicine preparation for herpangina according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Radix Rehmanniae 15g, Radix Rehmanniae Preparata 15 g, Fructus Forsythiae 15 g, Flos Lonicerae 12 g, Herba Lophatheri 12 g, Caulis Akebiae 9 g, Sichuan Herba Dendrobii 18 g, Radix Sophorae Tonkinensis 10 g, Folium Isatidis 15 g, Flos Chrysanthemi Indici 9 g, Cortex Phellodendri 12 g, Radix Scutellariae 12 g, Rhizoma Coptidis 6 g, Gypsum Fibrosum 24 g, the Rhizoma Anemarrhenae 12 g, Aloe 10 g, Radix Asparagi 12 g, Radix Ophiopogonis 12 g, Radix Scrophulariae 15 g, the Radix Paeoniae Alba 15 g, Radix Adenophorae (Radix Glehniae) 15 g, Radix Trichosanthis 18 g, Indigo Naturalis 10g, calamitas urinae hominis 9g, Radix Glycyrrhizae 6 g.

3. a kind of Chinese medicine preparation for herpangina according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is decoction.

4. for a preparation method for the Chinese medicine preparation of herpangina, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, gets Radix Rehmanniae Preparata and pulverizes ground 100 mesh sieves, for subsequent use; Get Aloe, smash 100 mesh sieves to pieces, for subsequent use; Get calamitas urinae hominis, smash 160 mesh sieves to pieces, for subsequent use; Get Indigo Naturalis, smash 160 mesh sieves to pieces, for subsequent use; Step 2: by weight proportion of the present invention, get Radix Rehmanniae, Fructus Forsythiae, Flos Lonicerae, Herba Lophatheri, Caulis Akebiae, Sichuan Herba Dendrobii, Radix Sophorae Tonkinensis, Folium Isatidis, Flos Chrysanthemi Indici, Cortex Phellodendri, Radix Scutellariae, Rhizoma Coptidis, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Radix Asparagi, Radix Ophiopogonis, Radix Scrophulariae, the Radix Paeoniae Alba, Radix Adenophorae (Radix Glehniae), Radix Trichosanthis, Radix Glycyrrhizae removing impurity, clean, run through, drying, for subsequent use; Step 3: by weight proportion of the present invention, is placed in marmite by step 2 Radix Adenophorae (Radix Glehniae), Radix Scrophulariae, adds the water that triploid is long-pending, slow fire infusion 15 ~ 20 minutes, and filter, infusion three times repeatedly, merging filtrate, discards filtering residue, for subsequent use; Step 4: by weight proportion of the present invention, step 2 Chinese crude drug Radix Rehmanniae, Caulis Akebiae, Sichuan Herba Dendrobii, Radix Sophorae Tonkinensis, Cortex Phellodendri, Radix Scutellariae, Rhizoma Coptidis, Gypsum Fibrosum, the Rhizoma Anemarrhenae, Radix Asparagi, Radix Ophiopogonis, the Radix Paeoniae Alba, Radix Trichosanthis, Radix Glycyrrhizae medical material are placed in marmite, add the water of 4 times of volumes, intense fire infusion 10 ~ 15 minutes, fiery infusion of larding speech with literary allusions is filtered for 20 ~ 30 minutes, add the water of 2 times of volumes again, Fructus Forsythiae, Flos Lonicerae, Herba Lophatheri, Folium Isatidis, Flos Chrysanthemi Indici are dropped in marmite, slow fire infusion 20 ~ 30 minutes, infusion merges gained filtrate three times repeatedly, discard filtering residue, for subsequent use; Step 5: powder mixing in combining step three and step 4 gained filtrate and step one, stirs evenly, both Chinese medicine decoction of the present invention.