CN113975216A

CN113975216A - Body care product composition with whitening effect and preparation method and application thereof

Info

Publication number: CN113975216A
Application number: CN202111397909.1A
Authority: CN
Inventors: 李宗厚; 杨帆; 周紫燕; 李沫; 郭苗; 周正
Original assignee: Hubei Maishite Biotechnology Co Ltd
Current assignee: Hubei Maishite Biotechnology Co Ltd
Priority date: 2021-11-23
Filing date: 2021-11-23
Publication date: 2022-01-28
Anticipated expiration: 2041-11-23
Also published as: CN113975216B

Abstract

The invention discloses a body care product composition with a whitening effect and a preparation method thereof. The body care product composition mainly comprises the following raw materials: 0.5-36% of functional raw materials and 64-99.5% of cosmetic auxiliary material matrix. Wherein the functional raw materials comprise: 0.1-10% of olive fruit extract, 0.1-10% of bletilla striata root extract, 0.1-5% of papain and 0.1-10% of ginkgo leaf extract. The functional component has the effects of whitening and rejuvenating skin, not only can reduce the generation of skin melanin, but also can remove old cutin of the skin, enhance cell metabolism, relieve red swelling of the skin, and enable the skin to be fine, smooth, glossy and elastic. In addition, the appearance modifier is added into the body skin care product, so that the product has a concealing effect and a timely whitening effect, and meanwhile, the long-acting whitening component is added, so that the skin can be whitened fundamentally and improved.

Description

Body care product composition with whitening effect and preparation method and application thereof

Technical Field

The invention relates to a skin care product and a preparation method and application thereof, belongs to the technical field of daily chemicals, and particularly relates to a body care product composition with a whitening effect and a preparation method and application thereof.

Background

Whatever the season, care of the body is crucial, especially in terms of skin lightening. If the skin is dull and dull, the whole spirit of a person is greatly influenced, so that the body is nursed inevitably in any season, and every girl also wants to have smooth and white skin.

The skin is dull, uneven in complexion and dark yellow due to a plurality of reasons, and the most common reasons are that the skin is exposed to ultraviolet rays for a long time in environmental factors to form melanin of the skin, then the pigment is deposited on the surface of the skin, and when the cutin cannot normally renew metabolism for a long time, the skin is further darkened.

Secondly, the skin is dull and yellow due to long-time water shortage, and the skin becomes dry and folds, so that the skin naturally looks gray and yellow; in addition, skin aging can cause the skin to lose luster and turn dark yellow. In addition, there are some personal lifestyle factors that cause dull skin, such as: staying up all night, high pressure, alcohol abuse, smoking, insufficient sleep and the like all affect the health and normal metabolism of the skin. Finally, there are problems in that mosquito bites or scars left after skin injury in summer can also affect the skin tone uniformity of the whole skin.

How to use skin care products to solve these problems has been a problem that needs to be solved in the industry.

Disclosure of Invention

The invention aims to provide a body care product composition with whitening effect, which can achieve the aims of instant whitening and long-acting whitening by adding long-acting whitening effect components and skin appearance modifiers into skin care products, not only can meet the requirement of timely whitening, but also can make the skin smooth and white after long-term use.

Another object of the present invention is to provide a method for preparing a body care product composition with whitening effect, which can perform instant whitening and long-lasting whitening effects, which will be greatly appreciated by consumers.

Another object of the present invention is to provide a use of a body care product composition having whitening effect.

In order to achieve the purpose, the invention adopts the following technical scheme:

a body care product composition with whitening effect is composed of the following components by weight:

0.5-36% of functional raw materials comprising: 0.1-10% of olive fruit extract, 0.1-10% of bletilla striata root extract, 0.1-5% of papain, 0.1-10% of ginkgo leaf extract;

64-99.5% of a cosmetic adjuvant base comprising: 0.1-20% of emollient, 0.1-12% of emulsifier, 0.1-22% of humectant, 0.1-5% of appearance modifier, 0.1-12% of thickener, 0.1-5% of pH value regulator, 0.01-1% of essence and the balance of deionized water.

Preferably, the body care product composition with whitening effect is composed of the following components by weight:

0.5-20% of functional raw materials comprising: 0.1-5% of olive fruit extract, 0.1-5% of bletilla striata root extract, 0.1-2.5% of papain, 0.1-5% of ginkgo leaf extract;

80-99.5% of a cosmetic adjuvant matrix comprising: 0.1-10% of emollient, 0.1-8% of emulsifier, 0.1-15% of humectant, 0.1-2% of appearance modifier, 0.1-8% of thickener, 0.1-3% of pH value regulator, 0.01-0.5% of essence and the balance of deionized water.

Preferably, the body care product composition with the whitening effect comprises the following components in percentage by mass based on the total weight of the composition:

olive fruit extract: bletilla striata root extract: papain: ginkgo biloba leaf extract 1: (1-3): (0.1-0.5): (1-2.5).

Preferably, in the cosmetic auxiliary material matrix, the emollient is selected from one or more of vegetable oil and fat, Australian leaf seed oil, sunflower seed oil, phytosterol and low erucic acid rapeseed glyceride, shea butter and olive ethyl oleate;

the emulsifier is one or more selected from sorbitan olivate, sorbitan stearate glycerol stearate, PEG-100 stearate, and cetearyl glucoside;

the humectant is one or more selected from glycerol, propylene glycol, glycosyl trehalose, hydrogenated starch hydrolysate, panthenol and allantoin;

the appearance modifier is selected from one or two of titanium dioxide and pearl powder;

the thickening agent is selected from one or more of carbomer, xanthan gum and sodium acrylate/sodium acryloyldimethyl taurate copolymer;

the pH value regulator is selected from one or more of arginine, triethanolamine, sodium hydroxide, potassium hydroxide and tromethamine.

Preferably, the appearance modifier is capable of imparting a concealer effect to the body care composition with a timely whitening effect.

Preferably, the preparation method of the body care product composition with whitening effect comprises the following steps:

1) firstly, dissolving the thickening agent by deionized water, and uniformly stirring and dispersing;

2) adding a humectant into the mixed solution obtained in the step 1), stirring, heating to 80-85 ℃, and keeping the temperature and stirring for 10-25 minutes to obtain a water phase material;

3) dissolving emollient and emulsifier with deionized water, stirring, dispersing, and heating to 80-85 deg.C for complete dissolution to obtain oil phase material;

4) slowly adding the oil phase raw material into the water phase material under the homogenization state of 3000-4000 rpm, continuing to homogenize for 5-10 minutes, and then adding the pH value regulator;

5) stirring the mixed solution in the step 4), cooling to 40-45 ℃, adding an appearance modifier, stirring at the speed of 1200-;

6) stopping homogenizing, adding the functional raw materials and the essence, stirring for 10 minutes at the speed of 1200-;

7) after homogenizing, stirring at 200-.

A cosmetic comprises a body care product composition with whitening effect.

Specifically, the cosmetic is in a solvent dispersion or suspension form, or in the form of emulsified particles, or in a polymer-coated form.

Preferably, the body care product composition with whitening effect has a pH in the range of 4-10, preferably a pH in the range of 5-8, most preferably a pH in the range of 5-7.

By means of the technical scheme, the invention has the following beneficial effects:

1) the body care product composition with the whitening effect mainly comprises the following functional components: olive fruit extract, bletilla striata root extract, papain and ginkgo leaf extract. The four functional components are compounded simultaneously, so that the whitening and skin-refreshing effects are achieved, the generation of skin melanin can be reduced, old cutin of the skin can be removed, the cell metabolism is enhanced, the red and swollen skin is relieved, and the skin becomes fine, smooth, full of gloss and elastic.

2) According to the innovative body care product composition with the whitening effect, the appearance modifier is added, so that the body care composition has a concealing effect and a timely whitening effect.

Drawings

Fig. 1 is a graph showing the rate of change in skin color (ITA °) after 56 days in the experimental group and the control group;

FIG. 2 is a graph showing the skin brightness (L) after 56 days in the experimental group and the control group^*) The rate of change of (c);

FIG. 3 is a graph showing the results of the synergistic experiment in the examples.

Detailed Description

The invention discloses a body care product composition with a whitening effect. The main whitening functional components of the body care product composition comprise: olive fruit extract, bletilla striata root extract, papain and ginkgo leaf extract, and has the effects of long-acting whitening and the like.

(ii) olive fruit extract

The Olea europaea is also called Olea europaea and Olea europaea, is evergreen arbor of Oleaceae, Olea, and is native in China in the Zhonghai and coastal regions. The olive is rich in various proteins, carbohydrates, 17 amino acids, fats, vitamin C and minerals such as calcium, phosphorus, iron and the like required by human bodies, wherein the content of the vitamin C is 10 times that of the apple and 5 times that of the pear and the peach. It also has high calcium content and is easy to be absorbed by human body.

The cell culture method proves that the olive extract has strong activation effect on macrophage activity, one effect of the macrophage in the cortex is to phagocytize melanin, and the inhibition effect on the activity of B-16 melanocyte is combined, so the olive extract has whitening effect on the skin.

② bletilla striata root extract

Bletilla striata is a perennial herb of the orchid family, which grows in hillside grassy bushes, forests and valley shady and wet places. The method is widely distributed in China and rich in resources, and mainly produces Guizhou province, Sichuan province, Hunan province and the like. The cosmetic is prepared from dried tuber of rhizoma Bletillae, or fresh rhizoma Bletillae and its tuber. After the bletilla striata rhizome extract is added into cosmetics, the bletilla striata rhizome extract can supplement skin nutrition, eliminate excessive free radicals in the body, delay skin aging, and avoid dull complexion caused by skin wrinkles due to oxidation of protein in the skin and loss of a supporting structure of the skin.

③ papain

Is a proteolytic enzyme, naturally occurring in papaya, often referred to as "plant protease". The main effects of the papain are cutin removal, dead skin removal on the surface of the skin, old cutin accumulated on the surface of the skin for a long time is removed, and the skin blackening and yellowing caused by long-time accumulation of pigment are avoided.

Fourthly, ginkgo leaf extract

Ginkgo biloba is a plant with high medicinal value, and ginkgo biloba is one of the ancient tree species in China. The flavone component, manganese, molybdenum and other trace elements contained in the ginkgo leaves can also prevent the formation and deposition of pigments in the dermis, so as to achieve the effects of whitening the skin and preventing and treating pigment patches. The flavonol, amino acid, etc. can also effectively prevent the generation of wrinkles. The long-acting whitening effect can be effectively realized on the skin after the whitening agent is applied to a skin care product.

The present invention is illustrated by the following examples, which are provided for the purpose of further illustration only and are not intended to limit the scope of the present invention. Other insubstantial modifications and adaptations of the present invention can be made without departing from the scope of the present invention. Unless otherwise specified, the following percentages (%) are mass percentages. All the raw material components are commercially available products.

Examples 1 to 3

The body care product composition with the whitening effect comprises the following raw material components in percentage by weight as shown in table 1.

Table 1 raw material component ratio of example 1 (unit: mass%)

The preparation method of the body care product composition with whitening effect of the above example 1 comprises the following steps:

2) adding a humectant into the mixed solution obtained in the step 1), stirring, heating to 80 ℃, and keeping the temperature and stirring for 20 minutes to obtain a water-phase material;

3) dissolving the emollient and the emulsifier with deionized water, stirring and dispersing uniformly, and heating to 80 ℃ until completely dissolving to obtain an oil phase material;

4) slowly adding the oil phase raw material into the water phase material under the homogenization state of 3500 revolutions per minute, continuing to homogenize for 5 minutes, and then adding the pH value regulator;

5) stirring the mixed solution in the step 4), cooling to 45 ℃, adding an appearance modifier, stirring at 1300 r/min for 20 minutes, and then homogenizing at 3500 r/min for 15 minutes;

6) stopping homogenizing, adding 1 part of fructus Oleae Europaeae extract, 1 part of rhizoma Bletillae root extract, 0.5 part of papain, 1.4 parts of folium Ginkgo extract and essence, stirring at 1300 rpm for 10 min, and homogenizing at 3500 rpm for 5 min.

7) Stirring and cooling to 35 ℃ at the speed of 200 revolutions per minute after homogenizing is finished, and obtaining the body care product composition with the whitening effect, wherein the pH value of the body care product composition is 5.7.

The preparation process of the body care product composition with whitening effect of the above example 2 comprises the following steps:

2) adding a humectant into the mixed solution obtained in the step 1), stirring, heating to 82 ℃, and keeping the temperature and stirring for 12 minutes to obtain a water-phase material;

3) dissolving the emollient and the emulsifier with deionized water, stirring and dispersing uniformly, and heating to 85 ℃ until completely dissolving to obtain an oil phase material;

4) slowly adding the oil phase raw material into the water phase material under the homogenization state of 3000 r/min, continuing to homogenize for 9 min, and then adding the pH value regulator;

5) stirring the mixed solution in the step 4), cooling to 42 ℃, adding an appearance modifier, stirring at 1200 r/min for 20 minutes, and then homogenizing at 3000 r/min for 15 minutes;

6) stopping homogenizing, adding 1 part of fructus Oleae Europaeae extract, 2 parts of rhizoma Bletillae root extract, 0.4 part of papain, 2 parts of folium Ginkgo extract and essence, stirring at 1200 rpm for 10 min, and homogenizing at 3000 rpm for 5 min;

7) stirring and cooling to 38 ℃ at the speed of 200 revolutions per minute after homogenizing is finished, and thus obtaining the body care product composition with the whitening effect, wherein the pH value of the body care product composition is 5.9.

The preparation process of the body care product composition with whitening effect of the above example 3 comprises the following steps:

2) adding a humectant into the mixed solution obtained in the step 1), stirring, heating to 85 ℃, and keeping the temperature and stirring for 25 minutes to obtain a water-phase material;

4) slowly adding the oil phase raw material into the water phase material under the homogenization state of 3800 r/min, continuing to homogenize for 10 min, and then adding the pH value regulator;

5) stirring the mixed solution in the step 4), cooling to 45 ℃, adding an appearance modifier, stirring at 1500 rpm for 20 minutes, and then homogenizing at 4000 rpm for 20 minutes;

6) stopping homogenizing, adding 1 part of olive fruit extract, 3 parts of bletilla striata root extract, 0.3 part of papain, 2.5 parts of ginkgo leaf extract and essence, stirring at 1500 rpm for 10 minutes, and homogenizing at 4000 rpm for 5 minutes;

7) stirring and cooling to 38 ℃ at the speed of 300 revolutions per minute after homogenizing is finished, and thus obtaining the body care product composition with the whitening effect, wherein the pH value of the body care product composition is 5.6.

Test example for Effect verification

1. Safety test

Test samples: example 1;

the test method comprises the following steps: and (4) testing the safety by adopting a third-party detection mechanism. The selection area is not more than 50mm²And a suitable patch device having a depth of about 1mm, wherein about 0.02 to about 0.025ml (g) of the test substance is applied to the patch device in a closed patch test. The patch tester is attached to the curved side of the forearm of the subject, the subject is removed 24h later, the skin reaction is observed 0.5h, 24h and 48h after removal, and the result is recorded according to the skin reaction grading standard in the technical regulation for cosmetic safety 2015.

TABLE 2 Patch test results

Remarking: grading standard of skin reaction

Level 0: negative reaction;

level 1: carrying out suspicious reaction; only faint erythema;

and 2, stage: weak positive reaction (erythema reaction); erythema, infiltration, edema, and possibly papules;

and 3, level: strong positive reaction (herpes reaction); erythema, infiltration, edema, pimples, herpes; the reaction may be beyond the test area;

4, level: very strong response (fusional herpes response); erythema, severe infiltration, edema, fusional herpes, and response beyond the test area.

As can be seen from table 2 above, the prepared body care product showed no irritation and was a safe pass.

2. Stability test

Test samples: example 1;

the test method comprises the following steps: and (5) observing the appearance color, viscosity and pH value for three months according to internal control standard.

Table 3 stability test results

Time

45℃

40℃

37℃

25℃

5℃

-15℃

CYCLE

Illumination of light

1W

√

2W

√

3W

√

4W

√

2M

√

3M

√

As can be seen from the above Table 3, the prepared body care product composition has no significant changes in color, viscosity and pH value within three months under high and low temperature conditions or under illumination, which indicates that the essence milk has better stability.

3. Body care product whitening efficacy testing

Test samples: example 1 (experimental group), basic body milk without added efficacy ingredient (control group).

The test method comprises the following steps: apply the above medicine on the outer side of arm in the morning and evening. The test was carried out in a room at 20-22 ℃ and 40-60% relative humidity, and the subjects had to be acclimated for 15 minutes in the same environment.

The results were tested at the following 4 time periods, respectively:

before use of the sample (D0), after use of the sample for 14 days (D14), after use of the sample for 28 days (D28) and after use of the sample for 56 days (D56).

The detection items are as follows: skin color determinationInstrument for measuring the shape of a human body

CL400 is used to detect skin color (ITA) and luminance (L)^*)。

And (3) testing results: as shown in tables 4-5 and fig. 1-2, the experimental group can significantly improve the skin color value by 41.13% and the skin brightness by 45.11%, while the common basic body lotion is improved by only 11.3% and 10.57% in terms of skin color and skin brightness, which indicates that the composition of the body care product prepared by the method has obvious long-acting whitening and skin brightening effects.

TABLE 4 rate of change of skin color (ITA) after 56 days in the experimental and control groups

Time	After 14 days of use	After 28 days of use	After 56 days of use
				Experiment of	13.12％	22.47％	41.13％
Control	5.10％	7.27％	11.31％

TABLE 5 skin Brightness after 56 days in the experimental and control groups(L^*) Rate of change of

Time	After 14 days of use	After 28 days of use	After 56 days of use
				Experiment of	15.40％	20.34％	45.11％
Control	4.57％	6.65％	10.57％

4. Synergistic experiment of composition for improving skin glossiness

A body care product composition with whitening effect, the contents of the raw material components of comparative examples 1-14 are shown in the following tables 6-7.

TABLE 6 ingredient ratio of composition for body care products having whitening effect of comparative examples 1 to 7 (unit: mass%)

TABLE 7 ingredient ratio of composition of body care products having whitening effect of comparative examples 8 to 14 (unit: mass%)

The preparation process of the body care product composition with whitening effect of the above comparative example is the same as the preparation process of the above example 1.

The effects of example 1 and comparative examples 1 to 14 of the synergistic test of the body care product composition having whitening efficacy were verified, and the test procedures and results were as follows:

1. the tester: 150 healthy women (25-45 years old) divided into 15 groups of 10 persons each; each group used the same formulation.

2. Test samples: example 1, comparative examples 1 to 14;

3. the test method comprises the following steps: apply the above medicine on the outer side of arm in the morning and evening. The test was carried out in a room at 20-22 ℃ and 40-60% relative humidity, and the subjects had to be acclimated for 15 minutes in the same environment. The results were tested at the following 4 time periods, respectively: before use of the sample (D0), after use of the sample for 14 days (D14), after use of the sample for 28 days (D28) and after use of the sample for 56 days (D56).

4. Testing an instrument: skin color tester

CL400 is used to detect skin color (ITA) and luminance (L)^*)

5. And (3) testing the effect: skin color (ITA) and lightness (L) on day 56^*) The change rate of (A) is shown in Table 8 below.

TABLE 8 test group Effect

Sample (I)	ITA degree value change rate (%)	L^*Rate of change (%)
			Comparative example 1	16.04	17.43
Comparative example 2	13.93	18.21
			Comparative example 3	14.82	19.13
Comparative example 4	15.89	18.90
			Comparative example 5	20.10	24.91
Comparative example 6	18.15	25.94
			Comparative example 7	19.95	26.17
Comparative example 8	18.95	25.49
			Comparative example 9	20.12	23.52
Comparative example 10	19.11	25.23
			Comparative example 11	28.31	30.97
Comparative example 12	27.16	31.81
			Comparative example 13	26.36	32.30
Comparative example 14	28.45	30.12
			Example 1	41.13	45.11

As is clear from the results shown in FIG. 3 and Table 9, the change rate of ITA DEG in example 1 was 41.13%, the change rate in comparative examples 11-14 was 25 to 30%, the change rate in comparative examples 5-10 was 15 to 20%, and the change rate in comparative examples 1 to 4 was 12 to 16%.

L of example 1^*The change rate is 45.11%, the change rate of the comparative examples 11-14 is 28-32%, and the change rate of the comparative examples 5-10 is 22-26% change rate of comparative examples 1 to 4 was 12 to 16%, and skin whitening ability of example 1 was>Comparative examples 11 to 14>5-11>1-4, which shows that the four selected components have synergistic whitening effect when being compounded into a body care product, because the functional components can effectively inhibit the activity of skin melanocytes so as to reduce the generation and deposition of melanin, improve color spots, remove cutin and dead skin on the surface of the skin, remove old cutin accumulated on the surface of the skin for a long time, and avoid dullness of the skin caused by long-time accumulation of the pigment.

Each component produces a specific effect in whitening the skin, so that the body care product can have a longer-lasting whitening effect than a skin care product using only a single efficacy component.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.

Claims

1. A body care product composition with whitening effect is characterized by comprising the following components in percentage by weight of the total composition:

2. The body care product composition with whitening efficacy according to claim 1, wherein the body care product composition is composed of the following components by weight:

3. The body care product composition with whitening effect according to claim 2, wherein the body care product composition with whitening effect is prepared from the following raw materials in parts by mass:

4. Body care product composition with whitening effect according to any of claims 1 to 3, characterized in that:

the emollient is selected from one or more of vegetable oil, Australian leaf seed oil, sunflower seed oil, phytosterol and low erucic acid rapeseed glyceride, shea butter and olive ethyl oleate;

5. The method for preparing the body care product composition with whitening efficacy according to claim 4, characterized by comprising the following steps:

7) after the homogenization is finished, stirring at the speed of 200 plus 300 revolutions per minute and cooling to 35-38 ℃, thus obtaining the body care product composition with the whitening effect.

6. A cosmetic characterized by: the cosmetic comprises the body care product composition with the whitening effect prepared by the preparation method of claim 5.

7. The cosmetic of claim 6, wherein: the cosmetic is in the form of a solvent dispersion or suspension, or in the form of emulsified particles, or in the form of a polymer coating.

8. The cosmetic of claim 7, wherein: the prepared body care product composition has a pH in the range of 4-10, preferably a pH in the range of 5-8, most preferably a pH in the range of 5-7.