CN105640836B - A kind of surfactant and preparation method thereof containing lotus active constituent - Google Patents
A kind of surfactant and preparation method thereof containing lotus active constituent Download PDFInfo
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Abstract
The present invention provides a kind of surfactant and preparation method thereof containing lotus active constituent, the component of surfactant includes Nuciferine, lotus pollen, glycerol, 1,3-BDO, carbomer, azelaic acid derivant, vitamin E, neutralizer, hamamelis extract, Sodium Hyaluronate, methyl benzoate, bi-imidazolidinyl urea, ethoxylated hydrogenated castor oil, essence, deionized water.After surfactant of the present invention, absorbability, moisture retention, flexibility, smooth feeling, the elasticity of skin better than use traditional skin care water, and skin effect is good.
Description
Technical field
The present invention relates to skin care fields, more particularly to a kind of surfactant containing lotus active constituent and its preparation side
Method.
Background technique
Lotus is called lotus flower, is the perennial root water plant of Nymphaeceae Nelumbo, and lotus perennation is draft in water
Plant, rhizome is initially tiny such as finger, have it is horizontal walk rhizomes, i.e. our daily lotus rhizomes eaten.Leaf is round, is higher by the water surface, there is length
Petiole, tool thorn, grows at peltate.Flower Dan Sheng is on bennet top, and 10~20 centimetres of diameter；Sepal is caducous；Petal majority be it is red,
Pink or white；Majority is stamen；Lotus nut skin is more, and from life, embedding life is in spongy holder cave.Its nut it is oval or
It is oval, it is commonly called as lotus seeds.
Lotus whole body is treasured, and lotus root, leaf, petiole, lotus stamen, lotus pod (holder) can be used as medicine, can clearing away heat to stop bleeding；Lotus nut be (seed
Embryo) there are clearing away the heart-fire, heart tonifying antihypertensive effect；Lotus seeds (nut) have tonifying spleen and stopping diarrhea, relieving mental strain and strengthening the kidney effect.Lotus rhizome can for vegetable consumption or
It extracts starch (lotus root starch).Lotus original refers to its fruit, is commonly called as the seedpod of the lotus；Flower, fruit are all loosely referred to as lotus, and rhizomatous loose part claims
Lotus root.
The warm-natured bitter but sweet flavor of lotus, energy activating microcirculation and removing stasis medicinal, relieving summer-heat go heat toxin, can be used for treating traumatic injury, and lotus, which also has, dispels
The wet effect of weathering, can be used for treating wet sore scabies, and it is broken that when use takes lotus to rub, and it is effective to be affixed on red and swollen affected part.According to " herbal guiding principle
Mesh " it carries: lotus energy relieving palpitation QI invigorating takes lotus to cook congee with glutinous rice, then QI invigorating, which is preserved youthful looks, makes light of one's life by commiting suicide.Tao Hongjing cloud: " lotus flower relieving palpitation benefit color,
It preserves youthful looks and makes light of one's life by commiting suicide."
The moisture retention of skin, flexibility, smooth feeling, elasticity etc. are all poor after use for existing surfactant, and
Greasy feeling is stronger, and skin effect is not good enough, in the prior art there are no the active constituent of lotus to be applied in surfactant, does not have more
Corresponding production method.
Summary of the invention
In view of the foregoing deficiencies of prior art, the purpose of the present invention is to provide a kind of containing lotus active constituent
Surfactant, the skin effect for solving surfactant in the prior art is not good enough, using the moisture retention of skin after existing surfactant,
The problems such as flexibility, smooth feeling, elasticity etc. are all poor, and greasy feeling is stronger.
In order to achieve the above objects and other related objects, first aspect present invention provides a kind of containing lotus active constituent
Surfactant, the component including following parts by weight:
0.01-5 parts of Nuciferine, 0.01-10 parts of lotus pollen, 0.5-10 parts of glycerol, 0.5-10 parts of 1,3-BDO, card wave
0.05-0.5 parts of nurse, 0.1-4 parts of azelaic acid amino acid sylvite, 0.05-1 parts of vitamin E, 0.05-0.5 parts of neutralizer, North America gold
0.1-10 parts of thread prunus mume extract, 0.01-1 parts of Sodium Hyaluronate, 0.01-0.2 parts of methyl benzoate, bi-imidazolidinyl urea 0.01-
0.3 part, 0.01-1 parts of ethoxylated hydrogenated castor oil, 0.01-0.5 parts of essence, 60-90 parts of deionized water.
Further, the component including following parts by weight:
0.5-4 parts of Nuciferine, 1-8 parts of lotus pollen, 1-5 parts of glycerol, 2-8 parts of 1,3-BDO, carbomer 0.1-0.5
Part, 0.5-3 parts of azelaic acid amino acid sylvite, 0.1-0.6 parts of vitamin E, 0.1-0.3 parts of neutralizer, hamamelis extract
2-8 parts, 0.1-0.6 parts of Sodium Hyaluronate, 0.1-0.2 parts of methyl benzoate, 0.1-0.3 parts of bi-imidazolidinyl urea, ethoxylation
0.06-0.6 parts of rilanit special, 0.02-0.3 parts of essence, 65-85 parts of deionized water.
Further, the molecular weight of the Sodium Hyaluronate is 500,000 to 1,000,000.
Further, on the ethoxylated hydrogenated castor oil adduct number of ethylene oxide 20 or more.
Further, the neutralizer is the combination of one or more of potassium hydroxide, sodium hydroxide, triethanolamine.
It is highly preferred that the neutralizer is the combination of one or both of potassium hydroxide, sodium hydroxide.
Further, the essence is daily essence.
Second aspect of the present invention provides the preparation method of above-mentioned surfactant, includes the following steps:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in appropriate amount of deionized water, it will using neutralizer
The pH of carbomer solution is adjusted to 6.0-6.5, and after neutralizer dissolution completely, carbomer solution is in fully transparent state, then will be saturating
Bright matter acid sodium solution is mixed with carbomer solution, and glycerol, 1,3-BDO, hamamelis extract, lotus is added by formula ratio
Flower pollen, Nuciferine, azelaic acid amino acid sylvite, are sufficiently stirred mixing, heat, and keep the temperature 15min or more, then cool down, spare；
2) ethoxylated hydrogenated castor oil, vitamin E, essence are weighed by formula ratio, mixed, premixed liquid is made；Again should
Premixed liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added in the reserve liquid in step 1) after cooling,
Mixing, finished product is sufficiently stirred.Since vitamin E, essence belong to oily phase, if not in advance by the two with it is ethoxylated hydrogenated
Castor oil mixing, and in the cooling reserve liquid being directly added in step 1), turbid phenomenon can be generated, therefore, in advance by second
Oxygroup rilanit special is mixed with vitamin E, essence, plays solubilization, is avoided generating turbid phenomenon, is promoted each component
Dissolution.
Further, 80-85 DEG C is heated in the step 1).
Further, 35-40 DEG C is cooled in the step 1).
As described above, the surfactant and preparation method thereof of the invention containing lotus active constituent, has below beneficial to effect
Fruit:
Nuciferine is a kind of aporphine alkaloids contained in lotus leaf, is the main Lipid-lowering activities ingredient in lotus leaf；Lotus
Leaf alkali is extracted, ultrasonic wave assisted extraction, chloroform using the lotus leaf for shining dry grinding as raw material using cellulase pretreatment, dilute hydrochloric acid
Extraction serial of methods is extracted, and purity is 98% (i.e. mass fraction).Nuciferine is active tune in inventive formulation
Manage agent.
Lotus pollen be honeybee acquisition lotus essence, specially honeybee acquisition lotus pollen, then through honeybee processing and
At pollen dough.Its main dietotherapy ingredient is: protein, amino acid, vitamin, microelement, organized enzyme, flavonoids
Close object, lipid, nucleic acid, brassin, phytic acid etc..Wherein amino acid content and ratio are closest to FAO (Food and Agriculture Organization of the United Nation) (FAO)
The amino acid pattern of recommendation, this is extremely rare in wholefood.Lotus pollen is rich in protein, amino acid, and content is more than
5-7 times of egg, milk is referred to as " concentrated nutrition library " in nutrition.It is people that unsaturated fatty acid in pollen, which has several,
The essential fatty acid that body cannot synthesize.It is simultaneously also a kind of concentrate of natural vitamin, content is very high, and B family vitamin is abundant,
And there is the element of obvious effect also compared with horn of plenty human body beauty treatment.Lotus pollen adjusts endocrine, can promote endocrinal glands
Development, improve the secreting function of body of gland.It neutralizes a toxin, adjusts internal circulation system, restore and maintain body normal function；Beauty treatment
Beauty, anti-aging.Lotus pollen is not only conducive to human consumption's absorption, can also directly be absorbed and utilized for skin.Lotus pollen energy
Improve the nutritional status of Skin Cell, boost metabolism, delay cell senescence, increases skin elasticity, smooth away wrinkles, make skin
Soft health, smooth exquisiteness, skin whitening eliminate various spots, reduce wrinkle.For oral administration or external application lotus pollen can promote new old
Metabolism improves nutrition condition, enhances the vigor of skin and the resistance to extraneous poor environment.Lotus pollen is in inventive formulation
In be active additive, lotus pollen is a group under Bee Pollen, and the lotus pollen in the present invention is a kind of commercially available edible
High-quality Bee Pollen product, index meet " Bee Pollen " (GB/T30359-2013).
Glycerol: i.e. glycerine is colourless sweet clear and bright thick liquid.It is odorless, there is warm sweet taste, is commonly called as glycerol, it can be from air
Middle absorption moisture.Relative density 1.26362,17.8 DEG C of fusing point, 290.0 DEG C of boiling point (decomposition), index of refraction 1.4746, flash-point (is opened
Cup) 176 DEG C, acute toxicity: LD50:29600mg/kg (rat oral)；23500mg/kg (mouse oral).It can be used as solvent,
Lubricant, medicament and sweetener.Glycerol is used as moisturizer in the present invention.
1,3-BDO: 1,3-BDO has the characteristics that the reactive, odorless, less toxic of dihydric alcohol, good water solubility.At this
Moisturizer is used as in invention.In terms of moisturizing, since 1,3-BDO is small molecule moisturizing composition, so water ratio very little is grabbed,
Also there is certain bacteriostasis simultaneously.The safety of 1,3-BDO is higher, experiments have shown that, interruption smearing is being carried out to human body
When, it is primary every other day to smear, totally 16 days, in all 200 people for participating in test, all find no any irritating inflammation
Disease.About the irritation to eye mucous membrane, once there is researcher to be tested with white mouse, obtained result is still safety very
It is high.Researcher is added into the oral cavity test that surrounding is carried out in toothpaste, as a result, it is also nonirritant to mucous membrane of mouth, is one
The kind very high composition of safety.
Carbomer: acrylic resin, English name are Acrylic acid Polymers, and Chinese nickname is acrylic acid tree
Fat liquor, card wave are also referred to as carbomer (carbomer), are that the acrylic acid crosslinking being crosslinked with pentaerythrite etc. with acrylic acid is set
Rouge is a kind of very important rheology control agent, and No. CAS is 9003-01-4, and molecular formula is (C3H4O2) n, it is in a kind of chemical industry
Mesosome.Card wave after neutralization is outstanding gel-type vehicle, has the important uses such as thickening, suspension, simple process, stability is good, extensively
It is general to be applied to lotion, cream, in gel.Card wave be Nuo Yu company, the U.S. specialty (predecessor be U.S. Gu Lide company, the U.S.
One of most ancient company), product includes Carbopol series rheology modifier and the emulsification of Pemulen series polymer
Agent, Carbopol series rheology modifier have the models such as 934,941,940,980,981,1342.It is main in the invention patent
Using the models such as 941,981,1342, used as thickener.
Azelaic acid derivant: English name Azeloglicina；Chemical name is azelaic acid amino acid sylvite；Structure
Formula: R1-CO(CH2)7CO-R2-COOK；Characteristic: azelaic acid is a kind of traditional whitening and acne raw material of dispelling, but since its is insoluble
Property, fusing point is high and dosage is big, and easy to change, compatibility is poor, it is made to be very limited in application.Azelaic acid derivant is one
The derivative of the azelaic acid of kind recent development, it is soluble easily in water, and usage amount is few, and whitening function is strong, and has good adjusting
The effect of fat secretion.A large number of experiments proves, with excellent safety and stability.Purposes: inhibit skin seborrheica, dispel
Acne；Reverse transcriptase tyrosinase has whitening spot-removing effect, improves skin moisture-keeping ability, improves skin elasticity.Its quality
Index is as follows: character: colourless or pale yellow transparent aqueous solution, almost tasteless；Specific gravity: 1.160-1.170g/ml (25 DEG C)；pH
Value: 6.0-7.5；Substance content: 28-34%；Safety: this product safety with higher, it is almost non-stimulated to skin.It answers
With: suitable for whitening, acne of dispelling cream, lotion, water based product.
Vitamin E: vitamin E (Vitamin E) is a kind of liposoluble vitamin, and it is most that hydrolysate, which is tocopherol,
One of main antioxidant is soluble in the organic solvents such as fat and ethyl alcohol, not soluble in water, is stablized to heat, acid, to alkali shakiness
It is fixed, it is sensitive to oxygen, it is insensitive to heat, but Vitamin E activity is substantially reduced when frying.Tocopherol can promote sex hormone to secrete, and make
Man's sperm motility and quantity increase；Increase woman's female hormone concentration, improve fecundity, prevention of miscarriage, it may also be used for
Prevent and treat male sterility, burn, frostbite, capillary hemorrhage, climacteric syndrome, beauty etc..Appearance: clear viscous liquid
Body；Color: yellowish green, molecular formula: C29H50O2, molecular weight: 430.71, boiling point: 485.9 DEG C of at 760mmHg, refractive index:
1.495, shining point: 210.2 DEG C.
| Index subjet | Index request |
| Appearance | Transparent oily liquid, colourless almost colourless or light yellow or chartreuse |
| Smell | Free from extraneous odour |
| Heavy metal | ≤10ppm |
| Lead | ≤2ppm |
| Arsenic | ≤1ppm |
| Mercury | ≤1ppm |
| Cadmium | ≤0.5ppm |
Neutralizer: heretofore described neutralizer is acid neutralizing agent, plays the role of adjusting pH, can select hydroxide
The organic bases such as the inorganic bases such as potassium, sodium hydroxide or triethanolamine, since organic base easily causes to change colour, neutralizer is preferably
The inorganic bases such as potassium hydroxide, sodium hydroxide avoid having an impact the color of surfactant.
Hamamelis extract: hamamelis (H.virginiana) also known as Virginia witch hazel, are witch hazels
Section (Hamamelidaceae), a kind of machaka of Hamamelis (Hamamelis).Eastern North America is originated in, is taken by adding
Big Nova Scotia is to the Minnesota State west to the U.S., southwards to Florida State middle part and Texas east.North
The forked branch of U.S. witch hazel is considered as the excellent materials for doing detector bar (divining stick).The extract liquor of bark has convergent effect
Fruit is added in cosmetics and does astringent use, and the aboriginal in America can treat chafing, timber with bark and leaf
In reddish tan, sapwood near-white, material is careful, timber weight and hardness height, density 0.68.The extraction of branch, leaf and bark
It takes object that can be used for medicinal purpose, is mainly used to treat acne, bruise and swelling.The main component of extract includes tannic acid, does not eat
Sub- acid, catechin, procyanidine, Protoapigenone (Kaempferol, Quercetin), essential oil (carvacrol, eugenol, hexenol), choline
And saponin.The floral water (hydrosol) distilled can be used to skin care, it is a kind of very strong antioxidant and receipts
Agent is held back, it is highly effective when for treating whelk.It, which is also recommended, is used to treat chronic eczema, eczema, laceration of skin or get blister, mosquito
The illnesss such as sting, varication and hemorrhoid, it is also effective in cure for skin cuts, scratch and sunburn.In cosmetics, North America gold
Thread plum is used for anti-inflammatory, can mitigate stimulated skin, not will cause dry skin, and have effects that healing of wound, while it
Also play the role of to free radical resisting, the convergence effect and removal eye pouch effect of witch hazel are quite by favorable comment.Witch hazel loosen with
And abirritation has the skin of oily skin or allergy very excellent effect.Hamamelis extract has convergence hair
The effects of wet, quiet flesh, is mended in hole, plays the role of the cleaning of deeper, keeps the younger cunning of skin beautiful.Hamamelis extract also has
Fat secretion, moisturizing and net Bai Zuoyong are adjusted, convergence, calm skin are particularly suitable for the outermost layer of skin, rapidly permeate into skin, by interior
It is outer to adjust skin, balance skin pH value and fat secretion comprehensively, pore is purified, impaired skin is repaired, effectively adjusts diastole
Pore, hence it is evident that convergence enlarged pores prevent blackhead, acne from generating, make skin that fine and smooth, smooth, tight quickly be presented.
Sodium Hyaluronate: hyaluronic acid (Hyaluronic Acid, abbreviation HA) is glucuronic acid and N-acetylamino
The straight chain polymer mucopolysaccharide that the disaccharide repetitive unit of glucose connects and composes, Sodium Hyaluronate (SODIUM HYALURONATE)
For the substance extracted from cockscomb, it can also be fermented and be made by Lactococcus, the hyaluronic acid as commodity is generally its sodium salt,
That is Sodium Hyaluronate (Sodium Hyaluronate), traditionally still referred to as hyaluronic acid.Sodium Hyaluronate is emerging both at home and abroad
Advanced bio product, molecular weight be it is tens of thousands of to millions of, aqueous solution with high moisture retention, viscoplasticity and lubricity,
It is the bio-molecules being widely present in skin and other tissues, there is fabulous moisture-keeping function, is known as ideal in the world
Natural moisturizing factor (Natural MolsturlZlng Factor, NMF).It is the cosmetics found in current nature
With the best substance of performance of keeping humidity.Hyaluronic acid acts on skin surface, and macromolecular Sodium Hyaluronate can be formed in skin surface
It is wet to make skin smooth, and can obstruct the intrusion of alien bacteria, dust, ultraviolet light for one layer of ventilative film, protects the skin from
Infringement；Micromolecule hyaluronic acid sodium can penetrate into corium, have mild dilation capillary, increase blood circulation, improve intermediate generation
It thanks, promote skin-nourishing absorption, have the function of stronger wrinkle-chasing, skin elasticity, delay skin aging can be increased.Hyalomitome
Acid can also promote the proliferation and differentiation, scavenging activated oxygen of epidermal cell, can prevent and repair skin injury.The water of hyaluronic acid
Solution has very high viscosity, water phase can be made to thicken, and the lotion uniform and smooth with after oily mutually emulsification has stable emulsion effect.
Hyaluronic acid is the best natural moisture preserving ingredient of the cosmetics of super quality, and compatibility is good, and the additive amount in cosmetics is generally 0.05-
0.5wt%.This product is white or off-white color particle or powder, odorless, when dry, nitrogen content 2.8wt%-4.0wt%, and Portugal
Glucuronic acid content is 37.0wt%-51.0wt%；The efficient water lock moisturizer of toiletries and skin repair group are promoted sun-proof
The sun protection factor (spf value) of product assigns product water and moistens soft skin sense；With compact skin, permanent moisturizing, prevent dehydration,
The effects of promoting histocyte regeneration, Sodium Hyaluronate is moisture-regulating agent in the present invention.Hyalomitome of the present invention
For sour sodium molecule amount 500,000 to 1,000,000, specific targets are as follows:
| Index subjet | Index request |
| Appearance | White or off-white color particle or powder |
| Smell | It is odorless |
| PH value (0.5%) | 6.0-7.5 |
| Sodium Hyaluronate | >=92.0wt% |
| Glucuronic acid | >=44.0wt% |
| Heavy metal | ≤20ppm |
| Loss on drying | ≤ 8.0% |
| Protein content | ≤ 0.041% |
| Total number of bacteria | <10CFU/g |
| Mould and saccharomycete sum | <10CFU/g |
| Staphylococcus aureus | It must not detect |
| Pseudomonas aeruginosa | It must not detect |
Methyl benzoate: nickname benzoic acid methyl esters, chemical formula C8H8O2, molecular weight 136.15, CAS accession number 93-58-
3。
Bi-imidazolidinyl urea: English name is Diazolidinyl Urea, chemical constituent: diazonium alkyl imidazole urea, molecule
Formula: C13H20N8O10, molecular weight: 278.23, No. CAS: 78491-02-8.It is in the present invention preservative, is mainly used for inhibiting micro-
The breeding of biology.Action principle is sustained release formaldehyde, to Gram positive bacteria, Gram negative bacterium, including pseudomonas have it is antibacterial
Effect selectively inhibits saccharomycete, mould.
Ethoxylated hydrogenated castor oil: alias Crodaret, PEG-n rilanit special, rilanit special
Polyoxyethylene ether is obtained by rilanit special and ethylene oxide polymerization, nonionic surfactant, solid, is scattered in water to molten
Yu Shui, under strong acid, highly basic, facile hydrolysis has excellent emulsification, dispersion, solubilising, antistatic effect, has excellent calcium and magnesium
Dispersibility, it is irritant to skin, eyes, it is degradable.Product member includes hydrogenated castor oil polyoxyethylene ether -11, hydrogenation
Castor oil polyoxyethylene ether -20, hydrogenated castor oil polyoxyethylene ether -30, hydrogenated castor oil polyoxyethylene ether -50, hydrogenated castor
Oily polyoxyethylene ether -60, hydrogenated castor oil polyoxyethylene ether -75, hydrogenated castor oil polyoxyethylene ether -80, rilanit special are poly-
Ethylene oxide ether -100 etc., the present invention in ethoxylated hydrogenated castor oil be preferably ethoxy of the ethoxymer distribution 20 or more
The modified hydrogenated castor oil of baseization, plays the role of solubilized essence and oil-phase component.
Essence: it is specially daily essence, is in the present invention odorant.INCI (the international cosmetic raw material of daily essence
Name) entitled FRAGRANCE (" used referring to what state food pharmaceuticals administration general bureau issued on June 30th, 2014
Cosmetic material Names Catalogue ").
After surfactant of the present invention, absorbability, moisture retention, flexibility, smooth feeling, the elasticity of skin are better than used and are passed
System surfactant, skin effect are good.
Specific embodiment
Illustrate embodiments of the present invention below by way of specific specific example, those skilled in the art can be by this specification
Other advantages and efficacy of the present invention can be easily understood for disclosed content.The present invention can also pass through in addition different specific realities
The mode of applying is embodied or practiced, the various details in this specification can also based on different viewpoints and application, without departing from
Various modifications or alterations are carried out under spirit of the invention.
Embodiment 1
A kind of surfactant containing lotus active constituent, the component including following parts by weight:
5 parts of Nuciferine, 0.01 part of lotus pollen, 10 parts of glycerol, 0.5 part of 1,3-BDO, 0.5 part of carbomer, azelaic acid
4 parts of derivative, 0.05 part of vitamin E, 0.5 part of sodium hydroxide, 8 parts of hamamelis extract, 0.01 part of Sodium Hyaluronate,
0.5 part of methyl benzoate, 0.01 part of ethoxylated hydrogenated castor oil, 0.01 part of daily essence, is gone at 0.01 part of bi-imidazolidinyl urea
71 parts of ionized water.
The preparation method of above-mentioned surfactant includes the following steps:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in appropriate amount of deionized water, use sodium hydroxide
The pH to 6.0-6.5 of carbomer solution is adjusted, after sodium hydroxide dissolution completely, carbomer solution is in fully transparent state, then will
Sodium hyaluronate solution is mixed with carbomer solution, by formula ratio be added glycerol, 1,3-BDO, hamamelis extract,
Mixing is sufficiently stirred in lotus pollen, Nuciferine, azelaic acid derivant, is heated to 84 DEG C, keeps the temperature 15min or more, then be cooled to 39
DEG C, it is spare；
2) ethoxylated hydrogenated castor oil, vitamin E, daily essence are weighed by formula ratio, mixed, premixed liquid is made；Again
The premixed liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added spare after cooling in step 1)
In liquid, mixing is sufficiently stirred, inspection, after detection is qualified, finished product is packed in discharging.
Embodiment 2
0.5 part of Nuciferine, 8 parts of lotus pollen, 1 part of glycerol, 8 parts of 1,3-BDO, 0.4 part of carbomer, azelaic acid are derivative
0.5 part of object, 0.5 part of vitamin E, 0.45 part of triethanolamine, 2 parts of hamamelis extract, 0.5 part of Sodium Hyaluronate, benzene first
0.1 part of sour methyl esters, 0.4 part of bi-imidazolidinyl urea, 0.6 part of ethoxylated hydrogenated castor oil, 0.1 part of daily essence, deionized water
77 parts.
The preparation method of above-mentioned surfactant includes the following steps:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in appropriate amount of deionized water, use triethanolamine
The pH to 6.0-6.5 of carbomer solution is adjusted, after triethanolamine dissolution completely, carbomer solution is in fully transparent state, then will
Sodium hyaluronate solution is mixed with carbomer solution, by formula ratio be added glycerol, 1,3-BDO, hamamelis extract,
Mixing is sufficiently stirred in lotus pollen, Nuciferine, azelaic acid derivant, is heated to 83 DEG C, keeps the temperature 15min or more, then be cooled to 38
DEG C, it is spare；
2) ethoxylated hydrogenated castor oil, vitamin E, daily essence are weighed by formula ratio, mixed, premixed liquid is made；Again
The premixed liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added spare after cooling in step 1)
In liquid, mixing is sufficiently stirred, inspection, after detection is qualified, finished product is packed in discharging.
Embodiment 3
4 parts of Nuciferine, 1 part of lotus pollen, 5 parts of glycerol, 6 parts of 1,3-BDO, 0.2 part of carbomer, azelaic acid derivant 1
Part, 0.1 part of vitamin E, 0.2 part of potassium hydroxide, 6 parts of hamamelis extract, 0.1 part of Sodium Hyaluronate, methyl benzoate
0.2 part, 0.3 part of bi-imidazolidinyl urea, 0.5 part of ethoxylated hydrogenated castor oil, 0.2 part of daily essence, 75 parts of deionized water.
The preparation method of above-mentioned surfactant includes the following steps:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in appropriate amount of deionized water, use potassium hydroxide
Solution adjusts the pH to 6.0-6.5 of carbomer solution, and after potassium hydroxide dissolution completely, carbomer solution is in fully transparent state,
Sodium hyaluronate solution is mixed with carbomer solution again, glycerol, 1,3-BDO, hamamelis is added by formula ratio and extracts
Object, lotus pollen, Nuciferine, azelaic acid derivant, are sufficiently stirred mixing, are heated to 82 DEG C, keep the temperature 15min or more, then cool down
It is spare to 37 DEG C；
2) ethoxylated hydrogenated castor oil, vitamin E, daily essence are weighed by formula ratio, mixed, premixed liquid is made；Again
The premixed liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added spare after cooling in step 1)
In liquid, mixing is sufficiently stirred, inspection, after detection is qualified, finished product is packed in discharging.
Embodiment 4
3 parts of Nuciferine, 6 parts of lotus pollen, 4 parts of glycerol, 4 parts of 1,3-BDO, 0.4 part of carbomer, azelaic acid derivant 3
Part, 0.6 part of vitamin E, 0.4 part of potassium hydroxide, 4 parts of hamamelis extract, 0.6 part of Sodium Hyaluronate, methyl benzoate
0.4 part, 0.2 part of bi-imidazolidinyl urea, 1 part of ethoxylated hydrogenated castor oil, 0.3 part of daily essence, 72 parts of deionized water.
The preparation method of above-mentioned surfactant includes the following steps:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in appropriate amount of deionized water, use potassium hydroxide
The pH to 6.0-6.5 of carbomer solution is adjusted, after potassium hydroxide dissolution completely, carbomer solution is in fully transparent state, then will
Sodium hyaluronate solution is mixed with carbomer solution, by formula ratio be added glycerol, 1,3-BDO, hamamelis extract,
Mixing is sufficiently stirred in lotus pollen, Nuciferine, azelaic acid derivant, is heated to 81 DEG C, keeps the temperature 15min or more, then be cooled to 36
DEG C, it is spare；
2) ethoxylated hydrogenated castor oil, vitamin E, daily essence are weighed by formula ratio, mixed, premixed liquid is made；Again
The premixed liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added spare after cooling in step 1)
In liquid, mixing is sufficiently stirred, inspection, after detection is qualified, finished product is packed in discharging.
Embodiment 5
5 parts of Nuciferine, 2 parts of lotus pollen, 4 parts of glycerol, 2 parts of 1,3-BDO, 0.1 part of carbomer, azelaic acid derivant 2
Part, 0.5 part of vitamin E, 0.1 part of potassium hydroxide, 10 parts of hamamelis extract, 0.1 part of Sodium Hyaluronate, benzoic acid first
0.1 part of ester, 0.1 part of bi-imidazolidinyl urea, 0.06 part of ethoxylated hydrogenated castor oil, 0.02 part of daily essence, deionized water 74
Part.
The preparation method of above-mentioned surfactant includes the following steps:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in appropriate amount of deionized water, use potassium hydroxide
The pH to 6.0-6.5 of carbomer solution is adjusted, after potassium hydroxide dissolution completely, carbomer solution is in fully transparent state, then will
Sodium hyaluronate solution is mixed with carbomer solution, by formula ratio be added glycerol, 1,3-BDO, hamamelis extract,
Mixing is sufficiently stirred in lotus pollen, Nuciferine, azelaic acid derivant, is heated to 80 DEG C, keeps the temperature 15min or more, then be cooled to 35
DEG C, it is spare；
2) ethoxylated hydrogenated castor oil, vitamin E, daily essence are weighed by formula ratio, mixed, premixed liquid is made；Again
The premixed liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added spare after cooling in step 1)
In liquid, mixing is sufficiently stirred, inspection, after detection is qualified, finished product is packed in discharging.
The preparation of traditional skin care water:
Traditional skin care water includes the component of following parts by weight:
6 parts of glycerol, 3 parts of 1,3-BDO, 0.2 part of carbomer, 0.5 part of vitamin E, 0.1 part of neutralizer, double imidazolidines
0.1 part of base urea, 10 parts of hamamelis extract, 0.1 part of Sodium Hyaluronate, 0.5 part of ethoxylated hydrogenated castor oil, benzoic acid
0.1 part of methyl esters, 0.04 part of daily essence, 79.5 parts of deionized water.
Neutralizer therein can select one or more of potassium hydroxide, sodium hydroxide, triethanolamine to combine.
Above-mentioned traditional skin care water the preparation method is as follows:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in deionized water, adjusted and blocked using neutralizer
The pH to 6.0-6.5 of wave nurse solution, while being adjusted to carbomer solution in fully transparent state, then by sodium hyaluronate solution with
Carbomer solution mixing is added glycerol, 1,3-BDO, hamamelis extract by formula ratio, is sufficiently stirred and is uniformly dispersed,
It is heated to 80-85 DEG C, keeps the temperature at least 15 minutes, be cooled to 35-40 DEG C, it is spare；
2) ethoxylated hydrogenated castor oil, vitamin E, daily essence are weighed by formula ratio, mixed, premixed liquid is made；Again
The premixed liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added spare after cooling in step 1)
In liquid, mixing is sufficiently stirred, inspection, after detection is qualified, finished product is packed in discharging.
Using effect comparative experiments
Surfactant made from the embodiment of the present invention and homemade traditional skin care water are compared: 60 ages of selection exist respectively
Between 20-50 years old, the female volunteers of skin health it is on probation；Time on probation is one month, the trial employment period, in addition to can normally make
Except skin cleaning type cosmetics, other any skin-care cosmetics are not used, in order to avoid influence test result on probation.
It tried out, evaluated, given a mark, counted according to following evaluation index:
The absorbability of skin when use: the absorbability of impression evaluation skin when being used by trier according to oneself, respectively
It is given according to 0-5 and gives -0 point of evaluation marking to be poor, 5 points are very good；
Use the moisture retention of rear skin: the moisture retention by trier according to the impression evaluation skin after oneself use, respectively
It is given according to 0-5 and gives -0 point of evaluation marking to be poor, 5 points are very good；
Use the flexibility of rear skin: the flexibility by trier according to the impression evaluation skin after oneself use, respectively
Giving according to 0-5 and giving -0 point of evaluation marking is that flexibility is poor, and 5 points are very soft；
Use the smooth feeling of rear skin: the smooth degree by trier according to the impression evaluation skin after oneself use, point
It is not given according to 0-5 and gives -0 point of evaluation marking to be smooth, coarse not at all, 5 points are very smooth；
Use the elasticity of rear skin: by trier according to after oneself use impression evaluation skin elasticity, respectively according to
It is poor flexibility that 0-5, which gives and gives -0 point of evaluation marking, and 5 points very good for elasticity；
Use rear skin oil soapy feeling: the greasy situation by trier according to skin after oneself use, respectively according to 0-5 points
- 0 point of evaluation marking is given to be especially greasy, 5 points are greasy not at all.
1 in-service evaluation statistical form of table
Remarks: using the volunteer of self-control traditional skin care water and surfactant of the present invention during use without skin allergy feelings
Condition.
From upper table 1 it is apparent that using after surfactant of the present invention, the absorbability of skin, moisture retention, flexibility,
Smooth feeling, elasticity better than use traditional skin care water, and skin effect is good.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe
The personage for knowing this technology all without departing from the spirit and scope of the present invention, carries out modifications and changes to above-described embodiment.Cause
This, institute is complete without departing from the spirit and technical ideas disclosed in the present invention by those of ordinary skill in the art such as
At all equivalent modifications or change, should be covered by the claims of the present invention.
Claims (9)
1. a kind of surfactant containing lotus active constituent, which is characterized in that the component including following parts by weight:
0.01-5 parts of Nuciferine, 0.01-10 parts of lotus pollen, 0.5-10 parts of glycerol, 0.5-10 parts of 1,3-BDO, carbomer
0.05-0.5 parts, 0.1-4 parts of azelaic acid amino acid sylvite, 0.05-1 parts of vitamin E, 0.05-0.5 parts of neutralizer, North America gold thread
0.1-10 parts of prunus mume extract, 0.01-1 parts of Sodium Hyaluronate, 0.01-0.2 parts of methyl benzoate, bi-imidazolidinyl urea 0.01-0.3
Part, 0.01-1 parts of ethoxylated hydrogenated castor oil, 0.01-0.5 parts of essence, 60-90 parts of deionized water.
2. the surfactant according to claim 1 containing lotus active constituent, which is characterized in that including following parts by weight
Component:
0.5-4 parts of Nuciferine, 1-8 parts of lotus pollen, 1-5 parts of glycerol, 2-8 parts of 1,3-BDO, 0.1-0.5 parts of carbomer, nonyl
0.5-3 parts of diacid amino acid sylvite, 0.1-0.6 parts of vitamin E, 0.1-0.3 parts of neutralizer, hamamelis extract 2-8
It is part, 0.1-0.6 parts of Sodium Hyaluronate, 0.1-0.2 parts of methyl benzoate, 0.1-0.3 parts of bi-imidazolidinyl urea, ethoxylated hydrogenated
0.06-0.6 parts of castor oil, 0.02-0.3 parts of essence, 65-85 parts of deionized water.
3. the surfactant according to claim 1 or 2 containing lotus active constituent, it is characterised in that: the hyaluronic acid
The molecular weight of sodium is 500,000 to 1,000,000.
4. the surfactant according to claim 1 or 2 containing lotus active constituent, it is characterised in that: the ethoxylation
The adduct number of ethylene oxide is 20 or more on rilanit special.
5. the surfactant according to claim 1 or 2 containing lotus active constituent, it is characterised in that: the neutralizer is
The combination of one or more of potassium hydroxide, sodium hydroxide, triethanolamine.
6. the surfactant according to claim 1 or 2 containing lotus active constituent, it is characterised in that: the essence is day
Use essence.
7. the preparation method of the surfactant containing lotus active constituent according to claim 1-6,
It is characterized in that: including the following steps:
1) Sodium Hyaluronate, carbomer are weighed by formula ratio, be dissolved separately in appropriate amount of deionized water, using neutralizer by card wave
The pH of nurse solution is adjusted to 6.0-6.5, then sodium hyaluronate solution is mixed with carbomer solution, by formula ratio be added glycerol,
1,3-BDO, hamamelis extract, lotus pollen, Nuciferine, azelaic acid amino acid sylvite, are sufficiently stirred mixing, add
Heat keeps the temperature 15min or more, then cools down, spare；
2) ethoxylated hydrogenated castor oil, vitamin E, essence are weighed by formula ratio, mixed, premixed liquid is made；Again by the premix
Liquid and methyl benzoate, bi-imidazolidinyl urea, the deionized water of surplus are added in the reserve liquid in step 1) after cooling, sufficiently
It stirs and evenly mixs, finished product.
8. preparation method according to claim 7, it is characterised in that: be heated to 80-85 DEG C in the step 1).
9. preparation method according to claim 7, it is characterised in that: be cooled to 35-40 DEG C in the step 1).
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| 壬二酸的化学改性及产物抑制酪氨酸酶活性的研究;李杨等;《日用化学工业》;20140930;第44卷(第9期);第494-496、528页 |
| 菩璞中华味道莲识玉肌水露;重庆菩璞生物科技有限公司;《http://125.35.6.80:8080/ftba/itownet/hzp_ba/fw/pz.jsp?processid=20151113144335talzy&nid=20151113144335talzy》;20151127;第1-2页 |
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