CN113846013B - 一种药用海藻酸钠生产用酶解罐 - Google Patents
一种药用海藻酸钠生产用酶解罐 Download PDFInfo
- Publication number
- CN113846013B CN113846013B CN202111435666.6A CN202111435666A CN113846013B CN 113846013 B CN113846013 B CN 113846013B CN 202111435666 A CN202111435666 A CN 202111435666A CN 113846013 B CN113846013 B CN 113846013B
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- China
- Prior art keywords
- tank body
- stirring
- sodium alginate
- gear
- stirring shaft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 title claims abstract description 39
- 235000010413 sodium alginate Nutrition 0.000 title claims abstract description 39
- 239000000661 sodium alginate Substances 0.000 title claims abstract description 39
- 229940005550 sodium alginate Drugs 0.000 title claims abstract description 39
- 238000004519 manufacturing process Methods 0.000 title description 6
- 238000003756 stirring Methods 0.000 claims abstract description 101
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- 229910001220 stainless steel Inorganic materials 0.000 claims description 6
- 239000010935 stainless steel Substances 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 4
- 230000007071 enzymatic hydrolysis Effects 0.000 claims 2
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 claims 2
- 238000004090 dissolution Methods 0.000 abstract description 6
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/52—Mobile; Means for transporting the apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/12—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
- C12M41/24—Heat exchange systems, e.g. heat jackets or outer envelopes inside the vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Thermal Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Mixers Of The Rotary Stirring Type (AREA)
- Accessories For Mixers (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
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CN202111435666.6A CN113846013B (zh) | 2021-11-30 | 2021-11-30 | 一种药用海藻酸钠生产用酶解罐 |
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CN202111435666.6A CN113846013B (zh) | 2021-11-30 | 2021-11-30 | 一种药用海藻酸钠生产用酶解罐 |
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Publication Number | Publication Date |
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CN113846013A CN113846013A (zh) | 2021-12-28 |
CN113846013B true CN113846013B (zh) | 2022-03-22 |
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Families Citing this family (1)
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CN114456927B (zh) * | 2022-03-12 | 2022-11-08 | 江苏汉肽生物医药有限公司 | 一种保持内部均匀密封反应的酶解炉及其实施方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111621403A (zh) * | 2020-06-12 | 2020-09-04 | 苏州聚维元创生物科技有限公司 | 一种适用于秸秆纤维水解糖化的双搅拌模式恒温反应装置 |
CN211754974U (zh) * | 2020-01-14 | 2020-10-27 | 青岛市际源海藻有限责任公司 | 一种用于海藻酸钠生产的转化装置 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2216395A1 (en) * | 2009-02-09 | 2010-08-11 | Lonza Biologics plc. | Bioreactor for the cultivation of mammalian cells |
CN105969660A (zh) * | 2016-06-21 | 2016-09-28 | 上海艾魁英生物科技有限公司 | 快速溶解海藻酸钠的高剪切溶解缸装置 |
CN208244632U (zh) * | 2018-04-24 | 2018-12-18 | 许高杰 | 一种快速溶解海藻酸钠的溶解缸装置 |
CN209333617U (zh) * | 2018-12-27 | 2019-09-03 | 山东天晟生物科技有限公司 | 一种透明质酸钠复溶罐 |
CN213895876U (zh) * | 2020-11-19 | 2021-08-06 | 江苏康庭生物科技有限公司 | 利用壳聚糖制备壳寡糖用酶解罐 |
CN214808576U (zh) * | 2021-03-11 | 2021-11-23 | 海阳市鸿贸海藻有限公司 | 一种海藻酸钠生产用提取罐 |
CN214716505U (zh) * | 2021-04-25 | 2021-11-16 | 青海伊纳维康生物科技有限公司 | 一种用于快速生产海藻酸钠包埋颗粒的设备 |
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2021
- 2021-11-30 CN CN202111435666.6A patent/CN113846013B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN211754974U (zh) * | 2020-01-14 | 2020-10-27 | 青岛市际源海藻有限责任公司 | 一种用于海藻酸钠生产的转化装置 |
CN111621403A (zh) * | 2020-06-12 | 2020-09-04 | 苏州聚维元创生物科技有限公司 | 一种适用于秸秆纤维水解糖化的双搅拌模式恒温反应装置 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A kind of enzymatic hydrolysis tank for pharmaceutical sodium alginate production Effective date of registration: 20221018 Granted publication date: 20220322 Pledgee: Postal Savings Bank of China Limited Weihai Branch Pledgor: WEIHAI YINHE BIOLOGICAL TECHNOLOGY Co.,Ltd. Registration number: Y2022980018585 |
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CP03 | Change of name, title or address |
Address after: No. 99 Shuangcheng Road, Huancui District, Weihai City, Shandong Province, 264200 Patentee after: Weihai Galaxy Biotechnology Co.,Ltd. Address before: 264204 Yangting Town, Huancui District, Weihai City, Shandong Province Patentee before: WEIHAI YINHE BIOLOGICAL TECHNOLOGY Co.,Ltd. |
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Date of cancellation: 20231228 Granted publication date: 20220322 Pledgee: Postal Savings Bank of China Limited Weihai Branch Pledgor: WEIHAI YINHE BIOLOGICAL TECHNOLOGY Co.,Ltd. Registration number: Y2022980018585 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: An enzymatic hydrolysis tank for the production of medicinal sodium alginate Effective date of registration: 20240102 Granted publication date: 20220322 Pledgee: Postal Savings Bank of China Limited Weihai Branch Pledgor: Weihai Galaxy Biotechnology Co.,Ltd. Registration number: Y2023980075618 |
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