CN110623895A - Anti-allergy relieving composition and preparation method and application thereof - Google Patents
Anti-allergy relieving composition and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to an anti-allergy and soothing composition and a preparation method and application thereof. The raw materials of the anti-allergy and soothing composition comprise, by mass, 2-24% of a humectant, 0.1-0.8% of a thickener, 1-6% of a first plant extract, 1-10% of oat beta-glucan, 1-8% of a second plant extract, 0.3-0.9% of a preservative and 50.3-94.6% of a solvent. The raw materials are mutually matched and have synergistic effect, so that the anti-allergy and soothing composition has good water replenishing and moisturizing effects, and can repair damaged skin and maintain skin health.
Description
Technical Field
The invention relates to the field of daily chemicals, in particular to an anti-allergy and soothing composition and a preparation method and application thereof.
Background
The facial mask is a common skin care product, and is applied to the face in the using process, the pores of the skin are promoted to expand, the secretion and metabolism of sweat glands are promoted, and metabolites of epidermal cells and accumulated grease substances are eliminated under the action of the composition. Meanwhile, the nutrient components in the composition are supplemented into the skin, so that the facial skin is nursed. However, most of the facial masks in the market mainly have a moisturizing effect, and the repairing effect on the 'micro-damage' existing on the skin is not good enough.
Disclosure of Invention
Therefore, an anti-allergy soothing composition which has a good moisturizing effect and can repair damaged skin, and a preparation method and application thereof are needed.
An anti-allergy and relieving composition comprises the following raw materials in percentage by mass:
2 to 24 percent of humectant, 0.1 to 0.8 percent of thickener, 1 to 6 percent of first plant extract, 1 to 10 percent of oat beta-glucan, 1 to 8 percent of second plant extract, 0.3 to 0.9 percent of preservative and 50.3 to 94.6 percent of solvent;
the first plant extract comprises the following raw materials in percentage by mass (1.8-2.4): (0.6-1.1): (1.6-2.4): (2.5-3.5) the peach resin extract, the dendrobium officinale stem extract, the tremella fruiting body extract and the cistanche extract;
the second plant extract comprises the following raw materials in percentage by mass (1.6-2.1): (1-1.5): (0.5-1.2): (1.5-2.5): (2.8-3.4) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin and an extract from the root of Gastrodia elata.
In one embodiment, the humectant is one or more of butylene glycol, polyglycerol-10 and sodium hyaluronate.
In one embodiment, the humectant is 2-17% of butanediol, 100.1-5% of polyglycerol and 0.01-0.2% of sodium hyaluronate by mass percentage of the composition.
In one embodiment, the thickener is an ammonium acryloyldimethyl taurate/VP copolymer; and/or the presence of a gas in the gas,
the solvent is water; and/or the presence of a gas in the gas,
the preservative is one or more of caprylyl hydroximic acid, 1, 2-hexanediol and 1, 3-propylene glycol.
In one embodiment, the first plant extract is prepared from peach resin extract, dendrobium officinale stem extract, tremella fuciformis entity extract, cistanche extract, water, glycerin, trehalose and sodium pyrrolidone carboxylate.
In one embodiment, the second plant extract is derived from the group consisting of Astragalus membranaceus root extract, Saposhnikovia divaricata root extract, calendula officinalis flower extract, Albizia julibrissin flower extract, Gastrodia elata root extract, water, and butylene glycol.
A method of preparing an anti-allergy soothing composition as described in any one of the preceding embodiments, comprising the steps of:
mixing the humectant, the thickener and the solvent to obtain a mixed solution, controlling the temperature of the mixed solution to 82-85 ℃, and keeping the temperature for 15-30 min;
controlling the temperature of the mixed solution after heat preservation to be 40-45 ℃, and adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative.
Use of an anti-allergy soothing composition as described in any of the above embodiments in the preparation of a mask.
In one embodiment, the anti-allergy soothing composition is diluted 8-fold to 20-fold.
In one embodiment, the anti-allergy soothing composition is adsorbed on a mask substrate, which is any one of cotton, silk and non-woven fabrics.
The raw materials of the anti-allergy and soothing composition comprise, by mass, 2-24% of a humectant, 0.1-0.8% of a thickener, 1-6% of a first plant extract, 1-10% of oat beta-glucan, 1-8% of a second plant extract, 0.3-0.9% of a preservative and 50.3-94.6% of a solvent. The first plant extract comprises peach resin extract, dendrobium officinale stem extract, tremella fruiting body extract and cistanche extract as raw materials; the second plant extract comprises radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract and rhizoma Gastrodiae extract. The raw materials are mixed in a proper ratio, so that the functions of the raw materials can be fully exerted, and the raw materials are matched with each other and act synergistically to obtain the anti-allergy and soothing composition.
The anti-allergy soothing composition has good effects of moisturizing, resisting aging, improving and maintaining the moisture content of the skin for a long time, keeping the skin moist, smoothing the skin texture, and has good film forming property, so that the skin is smooth; meanwhile, the skin care cream has good anti-inflammatory effect, can repair skin micro-damage and has good anti-inflammatory and relieving effects. Meanwhile, the composition can promote macrophage to release interleukin-1 to accelerate collagen synthesis, resist aging, reduce skin wrinkles, improve skin elasticity and improve skin texture, has good transdermal absorption performance, and can promote wound healing and repair damaged skin. Furthermore, the composition has the effects of soothing, relieving itching, dispelling redness, diminishing swelling and inhibiting release of inflammatory factors/mediators, has the effect of immediately relieving skin irritation, can effectively reduce skin sensitivity symptoms, repairs skin barriers, is mild in effect, safe and non-toxic, and creates a long-acting and consolidated anti-sensitivity barrier for skin. The anti-allergy soothing composition has good moisturizing effect, and can repair damaged skin and maintain skin health.
The preparation method of the anti-allergy and relieving composition adds corresponding raw materials at different temperatures, so that the raw materials can be fully fused and fully reacted to form a uniform composition. The temperature of the mixed solution is controlled to be 82-85 ℃ and kept for 15-30 min, so that the effect of the composition is more stable, and the shelf life of the composition can be prolonged. The preparation method of the composition is simple and easy, does not need complex process steps, and is suitable for industrial production.
The anti-allergy soothing composition is applied to the preparation of the facial mask, and the prepared facial mask has good moisturizing effect, can repair damaged skin and maintain skin health.
Detailed Description
In order that the invention may be more fully understood, reference will now be made to the accompanying examples. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
The embodiment of the invention provides an anti-allergy and relieving composition, which comprises the following raw materials in percentage by mass:
2 to 24 percent of humectant, 0.1 to 0.8 percent of thickener, 1 to 6 percent of first plant extract, 1 to 10 percent of oat beta-glucan, 1 to 8 percent of second plant extract, 0.3 to 0.9 percent of preservative and 50.3 to 94.6 percent of solvent;
the first plant extract comprises the following raw materials in a mass ratio of (1.8-2.4): (0.6-1.1): (1.6-2.4): (2.5-3.5) peach resin extract, dendrobium officinale stem extract, tremella entity extract and cistanche deserticola extract;
the raw materials of the second plant extract comprise (1.6-2.1) by mass: (1-1.5): (0.5-1.2): (1.5-2.5): (2.8-3.4) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin and an extract from the root of Gastrodia elata.
Preferably, the anti-allergy and relieving composition is prepared from the following raw materials in percentage by mass:
2 to 24 percent of humectant, 0.1 to 0.8 percent of thickener, 1 to 6 percent of first plant extract, 1 to 10 percent of oat beta-glucan, 1 to 8 percent of second plant extract, 0.3 to 0.9 percent of preservative and 50.3 to 94.6 percent of solvent;
the first plant extract comprises the following raw materials in a mass ratio of (1.8-2.4): (0.6-1.1): (1.6-2.4): (2.5-3.5) peach resin extract, dendrobium officinale stem extract, tremella entity extract and cistanche deserticola extract;
the raw materials of the second plant extract comprise (1.6-2.1) by mass: (1-1.5): (0.5-1.2): (1.5-2.5): (2.8-3.4) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin and an extract from the root of Gastrodia elata.
In a specific example, the anti-allergy relieving composition comprises the following raw materials in percentage by mass:
5 to 18 percent of humectant, 0.2 to 0.6 percent of thickener, 1.5 to 4 percent of first plant extract, 1 to 8 percent of oat beta-glucan, 1 to 5 percent of second plant extract, 0.3 to 0.7 percent of preservative and 63.7 to 91 percent of solvent;
the first plant extract comprises the following raw materials in percentage by mass (2-2.4): (0.8-1.1): (1.6-2): (3-3.5) the peach resin extract, the dendrobium officinale stem extract, the tremella fruiting body extract and the cistanche extract;
the raw materials of the second plant extract comprise (1.8-2.1) by mass: (1-1.2): (0.8-1.2): (1.5-2.2): (2.8-3.1) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin and an extract from the root of Gastrodia elata.
Preferably, the anti-allergy and relieving composition is prepared from the following raw materials in percentage by mass:
5 to 18 percent of humectant, 0.2 to 0.6 percent of thickener, 1.5 to 4 percent of first plant extract, 1 to 8 percent of oat beta-glucan, 1 to 5 percent of second plant extract, 0.3 to 0.7 percent of preservative and 63.7 to 91 percent of solvent;
the first plant extract comprises the following raw materials in percentage by mass (2-2.4): (0.8-1.1): (1.6-2): (3-3.5) the peach resin extract, the dendrobium officinale stem extract, the tremella fruiting body extract and the cistanche extract;
the raw materials of the second plant extract comprise (1.8-2.1) by mass: (1-1.2): (0.8-1.2): (1.5-2.2): (2.8-3.1) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin and an extract from the root of Gastrodia elata.
In a specific example, the anti-allergy relieving composition comprises the following raw materials in percentage by mass:
5-10% of humectant, 0.3-0.5% of thickener, 2-4% of first plant extract, 2-4% of oat beta-glucan, 1-3% of second plant extract, 0.4-0.7% of preservative and 77.8-89.3% of solvent;
the first plant extract comprises the following raw materials in percentage by mass (2-2.2): (1-1.1): (1.8-2): (3-3.2) the peach resin extract, the dendrobium officinale stem extract, the tremella fruiting body extract and the cistanche extract;
the raw materials of the second plant extract comprise (2-2.1) by mass: (1-1.1): (0.8-1): (1.5-2): (2.8-3) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin, and an extract from the root of Gastrodia elata.
Preferably, the anti-allergy and relieving composition is prepared from the following raw materials in percentage by mass:
5-10% of humectant, 0.3-0.5% of thickener, 2-4% of first plant extract, 2-4% of oat beta-glucan, 1-3% of second plant extract, 0.4-0.7% of preservative and 77.8-89.3% of solvent;
the first plant extract comprises the following raw materials in percentage by mass (2-2.2): (1-1.1): (1.8-2): (3-3.2) peach resin extract, dendrobium officinale stem extract, tremella fruiting body extract and cistanche extract;
the raw materials of the second plant extract comprise (2-2.1) by mass: (1-1.1): (0.8-1): (1.5-2): (2.8-3) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin, and an extract from the root of Gastrodia elata.
According to the anti-allergy and soothing composition, the raw materials are properly proportioned, so that the functions of the raw materials can be fully exerted, the raw materials are mutually matched and have a synergistic effect to obtain the anti-allergy and soothing composition, the composition has good effects of moisturizing, resisting aging, improving and maintaining the moisture content of the skin for a long time, keeping the skin moist, smoothing the skin texture, and has good film-forming property, so that the skin is smooth; meanwhile, the skin repairing liquid has good anti-inflammatory effect, can repair skin micro-damage, and has good anti-inflammatory and relieving effects. Meanwhile, the composition can promote macrophage to release interleukin-1 to accelerate collagen synthesis, resist aging, reduce skin wrinkles, improve skin elasticity and improve skin texture, has good transdermal absorption performance, and can promote wound healing and repair damaged skin. Furthermore, the composition has the effects of soothing, relieving itching, dispelling redness, diminishing swelling and inhibiting release of inflammatory factors/mediators, has the effect of immediately relieving skin irritation, can effectively reduce skin sensitivity symptoms, repairs skin barriers, is mild in effect, safe and non-toxic, and creates a long-acting and consolidated anti-allergy barrier for skin. The anti-allergy soothing composition has good moisturizing effect, and can repair damaged skin and maintain skin health.
In the embodiment, the oat beta-glucan is supplemented with proper water and glycerol to improve the processing performance of the oat beta-glucan during preparation of the composition and improve the uniformity of the composition.
In a specific example, the humectant is one or more of butylene glycol, polyglycerol-10 and sodium hyaluronate.
In a specific example, the humectant is 2 to 17 percent of butanediol, 100.1 to 5 percent of polyglycerol and 0.01 to 0.2 percent of sodium hyaluronate by mass percentage of the composition.
Preferably, the humectant accounts for 3 to 15 percent of the composition by mass, the polyglycerol-100.1 to 5 percent of the composition by mass and the sodium hyaluronate 0.01 to 0.2 percent of the composition by mass.
More preferably, the humectant accounts for 5 percent of butanediol, 101 percent of polyglycerol and 0.03 percent of sodium hyaluronate in percentage by mass of the composition.
In one particular example, the thickener is an ammonium acryloyldimethyl taurate/VP copolymer.
In one particular example, the solvent is water. In this example, the composition raw materials in water can form a more uniformly dispersed system in water.
In a specific example, the preservative is one or more of caprylhydroxamic acid, 1, 2-hexanediol, and 1, 3-propanediol.
Preferably, the preservative is prepared by mixing caprylhydroxamic acid, 1, 2-hexanediol and 1, 3-propylene glycol according to the mass ratio of 3:2: 1.
In a specific example, the raw materials of the first plant extract are peach resin extract, dendrobium officinale stem extract, tremella entity extract, cistanche extract, water, glycerin, trehalose, and sodium pyrrolidone carboxylate.
In a specific example, the second plant extract is derived from the group consisting of Astragalus membranaceus root extract, Saposhnikovia divaricata root extract, calendula officinalis flower extract, Albizzia julibrissin flower extract, Gastrodia elata root extract, water, and butylene glycol.
An embodiment of the present invention further provides a method for preparing an anti-allergy and soothing composition, comprising the following steps:
mixing a humectant, a thickener and a solvent to obtain a mixed solution, controlling the temperature of the mixed solution to 82-85 ℃, and keeping the temperature for 15-30 min;
controlling the temperature of the mixed solution after heat preservation to be 40-45 ℃, and adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative.
The preparation method of the composition in the embodiment adds corresponding raw materials at different temperatures, so that the raw materials can be fully fused and fully reacted to form a uniform composition. The temperature of the mixed solution is controlled to be 82-85 ℃ and kept for 15-30 min, so that the effect of the composition is more stable, and the shelf life of the composition can be prolonged. The preparation method of the composition is simple and easy, does not need complex process steps, and is suitable for industrial production.
Preferably, the humectant, the thickener and the solvent are mixed at the temperature of 70-75 ℃, and are homogenized for 1-3 min at the stirring speed of 1100-1500 r/min in the mixing process, so that the humectant, the thickener and the dispersion in the solvent are more uniformly mixed.
More preferably, the temperature of the mixed solution is controlled to be 82-85 ℃, then the mixed solution is homogenized for 3-5 min at the stirring speed of 1100-1500 r/min, and then the mixed solution is subjected to heat preservation. The prepared composition is more uniform by homogenization.
The embodiment of the invention also provides application of the anti-allergy and soothing composition in preparation of a facial mask.
In one particular example, the anti-allergy soothing composition is diluted 8-fold to 20-fold.
In a specific example, the anti-allergy soothing composition is adsorbed on a mask substrate, which is any one of cotton cloth, silk and non-woven cloth.
In the embodiment, the composition is applied to the facial mask, and the prepared facial mask has good moisturizing effect, and can repair damaged skin and maintain skin health.
The following are specific examples:
the first plant extract used in examples 1 to 6 and comparative examples 1 to 4 was prepared from the following raw materials in a mass ratio of 2: 1: 2: 3: 3: 1: 2:1, the extract of peach resin, the extract of dendrobium officinale stem, the extract of tremella fruiting body, the extract of cistanche deserticola, water, glycerol, trehalose and sodium pyrrolidone carboxylate. The second plant extract used in examples 1 to 6 and comparative examples 1 to 4 was prepared from the following raw materials in a mass ratio of 2: 1: 1: 2: 3: 3: 1, radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, rhizoma Gastrodiae extract, water and butanediol.
Examples 1-6 and comparative examples 1-4 the preservative used was a mixture of caprylhydroxamic acid, 1, 2-hexanediol and 1, 3-propanediol in a mass ratio of 3:2: 1.
1. Raw materials of the anti-allergy and soothing composition:
(1) the mass percentages of the raw materials of the anti-allergy soothing composition in examples 1 to 6 are shown in table 1.
TABLE 1
(2) Raw materials of anti-allergy soothing compositions in comparative examples 1 to 5:
comparative example 1 differs from example 2 in that the first plant extract in example 2 was replaced with water.
Comparative example 2 differs from example 2 in that the second plant extract in example 2 was replaced with water.
Comparative example 3 is different from example 2 in that the first plant extract and the second plant extract in example 2 were both replaced with water.
Comparative example 4 differs from example 2 in that the oat beta-glucan in example 2 was replaced with water.
The composition of comparative example 5 is the composition of the anti-allergy repair essence mask of example 1 in chinese patent application No. 201910146864.7.
2. Preparation of anti-allergy soothing composition:
the anti-allergy soothing composition of example 1 is prepared by: mixing a humectant, a thickener and a solvent at 70 ℃, and homogenizing for 2min at a stirring speed of 1200r/min in the mixing process to obtain a mixed solution; the temperature of the mixed solution is controlled at 82 ℃, the mixed solution is homogenized for 3min at the stirring speed of 1200r/min, and then the temperature is kept for 20 min. Controlling the temperature of the mixed solution after heat preservation to be 45 ℃, adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative, uniformly stirring, and cooling to room temperature to obtain a transparent liquid, namely the anti-allergy and soothing composition in the embodiment 1.
Example 2 an anti-allergy soothing composition was prepared by: mixing a humectant, a thickener and a solvent at 75 ℃, and homogenizing for 2min at a stirring speed of 1200r/min in the mixing process to obtain a mixed solution; the temperature of the mixed solution is controlled to be 85 ℃, the mixed solution is homogenized for 3min at the stirring speed of 1200r/min, and then the temperature is kept for 25 min. Controlling the temperature of the mixed solution after heat preservation to be 45 ℃, adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative, uniformly stirring, and cooling to room temperature to obtain a transparent liquid, namely the anti-allergy and soothing composition in the embodiment 2.
Example 3 an anti-allergy soothing composition is prepared by: mixing a humectant, a thickener and a solvent at 75 ℃, and homogenizing for 3min at a stirring speed of 1200r/min in the mixing process to obtain a mixed solution; the temperature of the mixed solution is controlled to be 85 ℃, the mixed solution is homogenized for 3min at the stirring speed of 1200r/min, and then the temperature is kept for 20 min. Controlling the temperature of the mixed solution after heat preservation to be 45 ℃, adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative, uniformly stirring, and cooling to room temperature to obtain a transparent liquid, namely the anti-allergy and soothing composition in the embodiment 3.
Example 4 an anti-allergy soothing composition is prepared by: mixing a humectant, a thickener and a solvent at 72 ℃, and homogenizing for 1min at a stirring speed of 1400r/min in the mixing process to obtain a mixed solution; the temperature of the mixed solution is controlled at 82 ℃, the mixed solution is homogenized for 3min at the stirring speed of 1400r/min, and then the temperature is kept for 30 min. Controlling the temperature of the mixed solution after heat preservation to be 45 ℃, adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative, uniformly stirring, and cooling to room temperature to obtain a transparent liquid, namely the anti-allergy soothing composition in the embodiment 4.
Example 5 the anti-allergy soothing composition is prepared by: mixing a humectant, a thickener and a solvent at 70 ℃, and homogenizing for 2min at a stirring speed of 1200r/min in the mixing process to obtain a mixed solution; the temperature of the mixed solution is controlled at 82 ℃, the mixed solution is homogenized for 3min at the stirring speed of 1400r/min, and then the temperature is kept for 25 min. Controlling the temperature of the mixed solution after heat preservation to be 45 ℃, adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative, uniformly stirring, and cooling to room temperature to obtain a transparent liquid, namely the anti-allergy and soothing composition in the embodiment 5.
Example 6 the anti-allergy soothing composition was prepared by: mixing a humectant, a thickener and a solvent at 70 ℃, and homogenizing for 2min at a stirring speed of 1200r/min in the mixing process to obtain a mixed solution; the temperature of the mixed solution is controlled to be 85 ℃, the mixed solution is homogenized for 3min at the stirring speed of 1400r/min, and then the temperature is kept for 25 min. Controlling the temperature of the mixed solution after heat preservation to be 45 ℃, adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative, uniformly stirring, and cooling to room temperature to obtain a transparent liquid, namely the anti-allergy soothing composition in the embodiment 6.
The compositions of comparative examples 1 to 4 were prepared in the same manner as in example 2.
3. Performance testing of anti-allergy relief compositions.
(1) And testing heat resistance and cold resistance.
The compositions obtained in examples 1 to 6 and comparative examples 1 to 5 were diluted 10-fold with water, respectively. The pH values of the compositions after dilution were:
example 1 to example 6: 5.70, 5.75, 5.72, 5.76, 5.72, 5.68;
comparative examples 1 to 5: 5.45,5.44,5.56,5.37,5.66.
From the pH data, it is clear that the pH values of the diluted compositions in examples 1 to 6 and comparative examples 1 to 5 are weakly acidic, correspond to the pH environment of human skin, and are mild and non-irritating. It is illustrated that the compositions of examples 1 to 6 and comparative examples 1 to 5 all have suitable pH values.
And (3) heat resistance test: the diluted composition was stored at 45. + -. 2 ℃ for 90 days, and then returned to room temperature, and the appearance and odor of the composition were observed. The results showed that the compositions of examples 1 to 6 were free from any abnormal appearance and odor after being stored at 45. + -. 2 ℃ for 90 days. The compositions of comparative examples 1 to 5 were not abnormal in appearance and odor. It is shown that the compositions of examples 1 to 6 and comparative examples 1 to 5 all have good heat resistance.
Cold resistance test: the diluted composition was stored at-17. + -. 2 ℃ for 90 days, and then returned to room temperature, and the appearance and odor of the composition were observed. The results showed that the compositions of examples 1 to 6 were free from any abnormal appearance and odor after being stored at-17. + -. 2 ℃ for 90 days. The compositions of comparative examples 1 to 5 were not abnormal in appearance and odor. It is shown that the compositions of examples 1 to 6 and comparative examples 1 to 5 all have good heat resistance.
And (3) cycle testing: placing the diluted composition at 45 + -2 deg.C for 24h, then at room temperature for 24h, then at-17 + -2 deg.C for 24h, circulating for 5 times, then recovering to room temperature, and observing appearance and odor of the composition. The results show that the compositions of examples 1 to 6 had no abnormal appearance and odor after the cycle test. The compositions of comparative examples 1 to 5 were not abnormal in appearance and odor. It is shown that the compositions of examples 1 to 6 and comparative examples 1 to 5 all have good cold resistance.
(2) And (4) testing the anti-allergy and relieving effect.
The compositions of examples 1 to 6 and comparative examples 1 to 5 were diluted 10 times with water, respectively, and prepared into facial masks in the same process. 110 volunteers were randomly selected, 10 per group and divided into 11 groups. The facial masks prepared by using the compositions in examples 1-6 and comparative examples 1-5 are applied for 15min in the morning and evening respectively for 30 days by taking the group as a unit. The test results are shown in table 2, wherein the anti-allergy relieving effect score is in a score mode within a range of 1-10 points, 10 points are the best anti-allergy relieving effect, 1 point is the worst anti-allergy relieving effect, and the test results are the average value of each group.
TABLE 2 anti-allergic and soothing Effect test results
(3) Skin improvement effect test
The compositions of examples 1 to 6 and comparative examples 1 to 5 were prepared into masks by the same process. 110 volunteers were randomly selected, 10 per group and divided into 11 groups. The facial masks prepared by using the compositions in examples 1-6 and comparative examples 1-5 are respectively applied for 15min in the morning and evening for 30 days by taking the group as a unit.
The skin improvement effect of the user is tracked and tested, and the skin improvement effect comprises the moisture content lifting rate, the skin elasticity lifting rate, the fineness lifting rate, the wrinkle reduction rate and the like of the skin.
Wherein, the moisture content of the skin is measured by a skin moisture tester; the skin elasticity is measured by adopting a skin elasticity tester MPA580 of CK company, Germany, and using a Revisometer RV600 probe; the fineness and wrinkles are measured by a skin detector, specifically a Visia skin detector.
The test results are the average of each group. The test results are shown in table 3.
Table 3 skin improvement effect test results
As can be seen from the test results of tables 2 and 3, the facial masks of examples 1 to 6 have good anti-allergy soothing effects, repair damaged skin, and maintain skin health, compared to comparative examples 1 to 5. Meanwhile, the facial masks of examples 1 to 6 have good moisturizing effect, are helpful for resisting skin aging, reducing skin wrinkles, improving skin elasticity, improving skin texture and enabling the skin to be tender and smooth.
The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above examples only show some embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (10)
1. An anti-allergy relief composition characterized by: the material comprises the following raw materials in percentage by mass:
2 to 24 percent of humectant, 0.1 to 0.8 percent of thickener, 1 to 6 percent of first plant extract, 1 to 10 percent of oat beta-glucan, 1 to 8 percent of second plant extract, 0.3 to 0.9 percent of preservative and 50.3 to 94.6 percent of solvent;
the first plant extract comprises the following raw materials in percentage by mass (1.8-2.4): (0.6-1.1): (1.6-2.4): (2.5-3.5) the peach resin extract, the dendrobium officinale stem extract, the tremella fruiting body extract and the cistanche extract;
the second plant extract comprises the following raw materials in percentage by mass (1.6-2.1): (1-1.5): (0.5-1.2): (1.5-2.5): (2.8-3.4) an extract from the root of Astragalus membranaceus, an extract from the root of Saposhnikovia divaricata, an extract from calendula officinalis, an extract from Albizia julibrissin and an extract from the root of Gastrodia elata.
2. The anti-allergy soothing composition of claim 1, wherein: the humectant is one or more of butanediol, polyglycerol-10 and sodium hyaluronate.
3. The anti-allergy soothing composition of claim 1, wherein: the humectant accounts for 2 to 17 percent of the composition by mass, 100.1 to 5 percent of polyglycerol and 0.01 to 0.2 percent of sodium hyaluronate.
4. The anti-allergy soothing composition of claim 1, wherein: the thickening agent is an acryloyl dimethyl ammonium taurate/VP copolymer; and/or the presence of a gas in the gas,
the solvent is water; and/or the presence of a gas in the gas,
the preservative is one or more of caprylyl hydroximic acid, 1, 2-hexanediol and 1, 3-propylene glycol.
5. The anti-allergy soothing composition of any one of claims 1 to 4, wherein: the first plant extract is prepared from peach resin extract, dendrobium officinale stem extract, tremella fruiting body extract, cistanche extract, water, glycerol, trehalose and sodium pyrrolidone carboxylate.
6. The anti-allergy soothing composition of any one of claims 1 to 4, wherein: the second plant extract is prepared from radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, rhizoma Gastrodiae extract, water and butanediol.
7. A process for preparing an anti-allergy soothing composition as claimed in any one of claims 1 to 6, wherein: the method comprises the following steps:
mixing the humectant, the thickener and the solvent to obtain a mixed solution, controlling the temperature of the mixed solution to 82-85 ℃, and keeping the temperature for 15-30 min;
controlling the temperature of the mixed solution after heat preservation to be 40-45 ℃, and adding the first plant extract, the oat beta-glucan, the second plant extract and the preservative.
8. Use of an anti-allergy soothing composition as defined in any one of claims 1 to 6 in the preparation of a mask.
9. The use of claim 8, wherein: the anti-allergy relieving composition is diluted by 8 to 20 times.
10. Use according to any one of claims 8 to 9, wherein: the anti-allergy soothing composition is adsorbed on a mask base material, wherein the mask base material is any one of cotton cloth, silk and non-woven fabrics.
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| CN116509773B (en) * | 2023-06-15 | 2024-06-07 | 广州若诗生物科技有限公司 | Composition with multiple skin care effects and application thereof |
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