CN110114081A - 一种改善心脏病变的方法 - Google Patents
一种改善心脏病变的方法 Download PDFInfo
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- CN110114081A CN110114081A CN201780078125.8A CN201780078125A CN110114081A CN 110114081 A CN110114081 A CN 110114081A CN 201780078125 A CN201780078125 A CN 201780078125A CN 110114081 A CN110114081 A CN 110114081A
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- plasminogen
- drug
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/484—Plasmin (3.4.21.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
本发明涉及用于预防和/或治疗受试者高脂血症及其相关病症的方法,包括给药易患高脂血症、患有高脂血症或罹患其它疾病并伴有高脂血症的受试者预防和/或治疗有效量的纤溶酶原。本发明还涉及用于用于预防和/或治疗受试者高脂血症及其相关病症的包含纤溶酶原的药物、药物组合物、制品、试剂盒。
Description
PCT国内申请,说明书已公开。
Claims (69)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2016110174 | 2016-12-15 | ||
CNPCT/CN2016/110172 | 2016-12-15 | ||
CNPCT/CN2016/110168 | 2016-12-15 | ||
CN2016110168 | 2016-12-15 | ||
CNPCT/CN2016/110174 | 2016-12-15 | ||
CN2016110172 | 2016-12-15 | ||
PCT/CN2017/089068 WO2018107707A1 (zh) | 2016-12-15 | 2017-06-19 | 一种改善心脏病变的方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN110114081A true CN110114081A (zh) | 2019-08-09 |
Family
ID=62558191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201780078125.8A Pending CN110114081A (zh) | 2016-12-15 | 2017-06-19 | 一种改善心脏病变的方法 |
Country Status (7)
Country | Link |
---|---|
US (1) | US11389515B2 (zh) |
EP (1) | EP3556385A4 (zh) |
JP (1) | JP7194440B2 (zh) |
CN (1) | CN110114081A (zh) |
CA (1) | CA3047175A1 (zh) |
TW (1) | TWI677348B (zh) |
WO (1) | WO2018107707A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11207387B2 (en) | 2016-12-15 | 2021-12-28 | Talengen International Limited | Method and drug for preventing and treating obesity |
TW201822812A (zh) | 2016-12-15 | 2018-07-01 | 深圳瑞健生命科學硏究院有限公司 | 一種預防和治療肥胖症的方法 |
CA3046671C (en) | 2016-12-15 | 2023-08-08 | Talengen International Limited | Method for preventing and treating pulmonary fibrosis |
TWI677348B (zh) | 2016-12-15 | 2019-11-21 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種改善心臟病變的方法 |
US11938172B2 (en) | 2017-06-19 | 2024-03-26 | Talengen International Limited | Method for regulating and controlling GLP-1/GLP-1R and drug |
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CN101132788A (zh) * | 2005-03-01 | 2008-02-27 | 瑟维尔实验室 | 用于治疗和预防血栓形成疾病的香叶木素衍生物 |
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- 2017-06-19 WO PCT/CN2017/089068 patent/WO2018107707A1/zh unknown
- 2017-06-19 US US16/470,160 patent/US11389515B2/en active Active
- 2017-06-19 CN CN201780078125.8A patent/CN110114081A/zh active Pending
- 2017-06-19 EP EP17880564.4A patent/EP3556385A4/en active Pending
- 2017-06-19 JP JP2019532072A patent/JP7194440B2/ja active Active
- 2017-06-19 CA CA3047175A patent/CA3047175A1/en not_active Abandoned
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Also Published As
Publication number | Publication date |
---|---|
JP2020502155A (ja) | 2020-01-23 |
CA3047175A1 (en) | 2018-06-21 |
TWI677348B (zh) | 2019-11-21 |
TW201822798A (zh) | 2018-07-01 |
US20190343931A1 (en) | 2019-11-14 |
EP3556385A1 (en) | 2019-10-23 |
EP3556385A4 (en) | 2020-12-30 |
JP7194440B2 (ja) | 2022-12-22 |
WO2018107707A1 (zh) | 2018-06-21 |
US11389515B2 (en) | 2022-07-19 |
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