CN110114081A - 一种改善心脏病变的方法 - Google Patents

一种改善心脏病变的方法 Download PDF

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Publication number
CN110114081A
CN110114081A CN201780078125.8A CN201780078125A CN110114081A CN 110114081 A CN110114081 A CN 110114081A CN 201780078125 A CN201780078125 A CN 201780078125A CN 110114081 A CN110114081 A CN 110114081A
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plasminogen
drug
subject
myocardial
tissue
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李季男
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Talengen Institute of Life Sciences Co Ltd
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Talengen Institute of Life Sciences Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

本发明涉及用于预防和/或治疗受试者高脂血症及其相关病症的方法，包括给药易患高脂血症、患有高脂血症或罹患其它疾病并伴有高脂血症的受试者预防和/或治疗有效量的纤溶酶原。本发明还涉及用于用于预防和/或治疗受试者高脂血症及其相关病症的包含纤溶酶原的药物、药物组合物、制品、试剂盒。

Description

PCT国内申请，说明书已公开。

Claims (69)

  1. PCT国内申请，权利要求书已公开。
CN201780078125.8A 2016-12-15 2017-06-19 一种改善心脏病变的方法 Pending CN110114081A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN2016110174 2016-12-15
CNPCT/CN2016/110172 2016-12-15
CNPCT/CN2016/110168 2016-12-15
CN2016110168 2016-12-15
CNPCT/CN2016/110174 2016-12-15
CN2016110172 2016-12-15
PCT/CN2017/089068 WO2018107707A1 (zh) 2016-12-15 2017-06-19 一种改善心脏病变的方法

Publications (1)

Publication Number Publication Date
CN110114081A true CN110114081A (zh) 2019-08-09

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CN201780078125.8A Pending CN110114081A (zh) 2016-12-15 2017-06-19 一种改善心脏病变的方法

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Country Link
US (1) US11389515B2 (zh)
EP (1) EP3556385A4 (zh)
JP (1) JP7194440B2 (zh)
CN (1) CN110114081A (zh)
CA (1) CA3047175A1 (zh)
TW (1) TWI677348B (zh)
WO (1) WO2018107707A1 (zh)

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CA3046671C (en) 2016-12-15 2023-08-08 Talengen International Limited Method for preventing and treating pulmonary fibrosis
TWI677348B (zh) 2016-12-15 2019-11-21 大陸商深圳瑞健生命科學研究院有限公司 一種改善心臟病變的方法
US11938172B2 (en) 2017-06-19 2024-03-26 Talengen International Limited Method for regulating and controlling GLP-1/GLP-1R and drug

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JP2020502155A (ja) 2020-01-23
CA3047175A1 (en) 2018-06-21
TWI677348B (zh) 2019-11-21
TW201822798A (zh) 2018-07-01
US20190343931A1 (en) 2019-11-14
EP3556385A1 (en) 2019-10-23
EP3556385A4 (en) 2020-12-30
JP7194440B2 (ja) 2022-12-22
WO2018107707A1 (zh) 2018-06-21
US11389515B2 (en) 2022-07-19

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