CN109231151A - A kind of device and application for making self-assembly structure - Google Patents
A kind of device and application for making self-assembly structure Download PDFInfo
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- CN109231151A CN109231151A CN201811125805.3A CN201811125805A CN109231151A CN 109231151 A CN109231151 A CN 109231151A CN 201811125805 A CN201811125805 A CN 201811125805A CN 109231151 A CN109231151 A CN 109231151A
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- microchannel
- assembly
- self
- flexible formwork
- nano
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
- B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B3/00—Devices comprising flexible or deformable elements, e.g. comprising elastic tongues or membranes
- B81B3/0064—Constitution or structural means for improving or controlling the physical properties of a device
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y40/00—Manufacture or treatment of nanostructures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/02—Sensors
- B81B2201/0278—Temperature sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/02—Sensors
- B81B2201/0292—Sensors not provided for in B81B2201/0207 - B81B2201/0285
Abstract
The device and application that the embodiment of the invention discloses a kind of for making self-assembly structure, comprising: a planar substrates;One Flexible formwork assembly;Its bottom is bonded the upper surface for being set to the planar substrates;And the bottom of the Flexible formwork assembly being bonded with the substrate of glass be provided with it is communicating with the outside world, for so that the microchannel that extraneous nano-particle solution flows into.By upper, the application may be implemented to be precisely controlled self-assembly position, and simple to operation.
Description
Technical field
The present invention relates to field of nanometer material technology, and in particular to a kind of device for making self-assembly structure and
Using.
Background technique
Nanoparticle (such as gold nanorods) is very sensitive to the absorption of surrounding medium, and the substance for being adsorbed on its interface can draw
The variation for playing its surface plasma resonance frequency, is embodied in the change of the optical signals such as light absorption and Surface enhanced Raman spectroscopy
Change, therefore the unmarked highly sensitive inspection to molecule may be implemented using nanoparticle as a kind of sensing element building sensor
It surveys.It may be implemented to carry out markless detection to molecule using nanoparticle at present, but this detection is in solution mostly
Carried out under environment, and under solution state nanoparticle be easy by extraneous ion concentration influenced occur coagulation can not be widely used in
Sensing, then it is found that gold nanoparticle is assembled in substrate it is possible to prevente effectively from coagulation bring influences, while also sending out
Existing regularly arranged nanoparticle three-dimensional structure can increase substantially detection sensitivity.
It is solvent evaporated method that nanoparticle, which is commonly assembled in the method in substrate, and solvent evaporated method is by colloidal nano
Particle solution drips in solid substrate, and nanoparticle is assembled in substrate after the completion of equal solvent evaporation.Although solvent evaporated method holds
Easily implement, but solvent evaporation is carried out directly in substrate can not accurately control the direction and position of self-assembly.
Therefore, need at present it is a kind of for making the device of self-assembly structure, with realize accurately control nanometer
The direction and position of particle self assembly.
Summary of the invention
In view of this, the main purpose of the present invention is to provide a kind of for making the dress of self-assembly structure
It sets and applies, to realize the accurate control to self-assembly position.
The application provides a kind of for making the device of self-assembly structure characterized by comprising
One planar substrates;
One Flexible formwork assembly;Its bottom is bonded the upper surface for being set to the planar substrates;And the Flexible formwork assembly with institute
State planar substrates fitting bottom be provided with it is communicating with the outside world, for so that extraneous nano-particle solution flow into it is micro- logical
Road.
By upper, the application covers Flexible formwork assembly on a planar base, and under the action of capillary force, nano-particle solution can flow
Enter in the microchannel in template, so that nanoparticle is carried out self assembly according to the structure of the microchannel in template, to secure gold
Position of the nanometer rods in substrate realizes the accurate control to self-assembly position.And the application is based on above-mentioned micro-
The uniform self-assembly structure of structure can be generated in channel, overcomes and in the prior art carries out directly in substrate
When solvent evaporates, since the influence of " coffee ring " effect causes the nano particle structure of assembling inhomogenous, and then nanoparticle is influenced
Defect of the son to the sensitivity of Molecular Detection.
Preferably, described device, further includes:
Control appliance of temperature and humidity, for controlling the temperature and humidity of the microchannel regional environment.
By upper, the application controls the temperature humidity of microchannel regional environment by setting control appliance of temperature and humidity to be suitable for
The evaporation of nano-particle solution is stated, to be more advantageous to the self assembly of nanoparticle.
Preferably, the structure of the microchannel are as follows: the channel-type structure that end communicates with the outside world.
By upper, the structure of the microchannel of the application can according to need the change for carrying out size and shape, and microchannel is end
Portion communicates with the outside world channel-type structure, can be added dropwise to the nano-particle solution of the end under the action of capillary force,
It is flowed into the channel-type structure in template by end.
Preferably, the channel-type structure are as follows: end communicate with the outside world through the Flexible formwork assembly bottom single or
The channel-type structure of a plurality of parallel interval.
By upper, pass through above-mentioned channel-type structure, the self-assembly of available single or a plurality of parallel interval
Structure.
Preferably, the width of the microchannel is following first, 2.5 μm, 3 μm, 5 μm to include, but is not limited to;
Spacing between the microchannel is following first, 5 μm, 7 μm, 10 μm to include, but is not limited to.
By upper, microchannel can be a plurality of channel-type structure of any of the above-described width of equivalent width, be also possible to basis
The a plurality of channel-type structure for the different in width for needing to be arranged, the width and the size of space of above-mentioned microchannel are that one kind can be suitable for receiving
Rice corpuscles solution flows into and in the appropriate size of assembling wherein, and other any appropriate sizes are also all the application's
Within protection scope.
Preferably, the planar substrates are as follows:
Common plane sheet glass, quartzy flat glass, conductive transparent surface glass, plated film flat glass or planar silicon material
Material.
By upper, the substrate is the planar substrates being not limited to above, and the planar structure of other any materials is all in the application
Protection scope.
Preferably, the Flexible formwork assembly is polydimethylsiloxane template or polymetylmethacrylate mould
Plate.
By upper, the Flexible formwork assembly is not limited to above-mentioned template, and others can etch the fluid channel with capillary force
Flexible formwork assembly is all in the protection scope of the application.
Preferably, the microchannel of the Flexible formwork assembly bottom be set as setting is handled by Soft lithograph mode.
By upper, template bottom is micro- by the recess of very small dimensions such as the available micron of processing of Soft lithograph, nanometer be micro-
Channel.Nano-particle solution is advantageously allowed to flow into the microchannel under the action of capillary force of above-mentioned microchannel, and
Self assembly in it.
The application also provides a kind of production method of self-assembly structure, based on above-mentioned device, comprising:
Nano-particle solution is dropped to the end of the microchannel, so that the nano-particle solution is by the flexible die
It under the action of the capillary force of the microchannel of plate, flows into the microchannel, and carries out self assembly in the microchannel, formed
The super crystal structure of three-dimensional of rule.
By upper, the application realizes the accurate control to self-assembly position.
Preferably, the method, further includes:
By controlling the temperature and humidity of the microchannel regional environment, to obtain the nanoparticle of required different shape
Self-assembled structures.
After the completion of nano-particle solution volatilization, the Flexible formwork assembly is removed, is fixed on planar substrates to obtain
On self-assembly regularization structure.
By upper, the application controls the temperature humidity of microchannel regional environment by setting control appliance of temperature and humidity to be suitable for
The evaporation of nano-particle solution is stated, to be more advantageous to the self assembly of nanoparticle.After the completion of nano-particle solution volatilization,
It is described to remove the Flexible formwork assembly, just acquire the rule after fixing micro particles self assembly on a planar base
Three-dimensional super crystal structure.
In conclusion the device provided by the present application for making self-assembly structure and the system based on the device
Accurate control to self-assembly position may be implemented in the method for making self-assembly structure, and can be according to need
The super crystal structure of three-dimensional of rule after generating specified size, uniform self-assembly.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is this hair
Bright some embodiments for those of ordinary skill in the art without any creative labor, can be with
It obtains other drawings based on these drawings.
Fig. 1 is the main view of the structure of the device for making self-assembly structure of the embodiment of the present invention;
Fig. 2 be the embodiment of the present invention for make self-assembly structure device structure planar substrates and
The enlarged diagram of the contact portion of Flexible formwork assembly;
Fig. 3 is the device that is used to make self-assembly structure of the nanoparticle in the application of the embodiment of the present invention
The top view of microarray after middle completion self assembly;
Fig. 4 is a kind of flow diagram of the production method of self-assembly structure of the embodiment of the present invention.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention
In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is
A part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art
Every other embodiment obtained without creative efforts belongs to the section that the present invention protects.
Embodiment one
As shown in Figure 1, 2, the present invention provides a kind of for making the device of self-assembly structure, comprising:
One planar substrates 110;Wherein, the planar substrates are as follows: common plane sheet glass, transparent is led quartzy flat glass
Level surface glass, plated film flat glass or plane silicon materials.The substrate is the planar substrates being not limited to above as a result, other
The planar structure of any material is all in the protection scope of the application.
One Flexible formwork assembly 120;Its bottom is bonded the upper surface for being set to the planar substrates;And the Flexible formwork assembly with
The bottom of planar substrates fitting be provided with it is communicating with the outside world, for so that extraneous nano-particle solution 130 flowed into
Microchannel 121.Wherein, the microchannel of the Flexible formwork assembly bottom is to be obtained by Soft lithograph mode.Template bottom passes through soft quarter
The microchannel for the recess of very small dimensions such as the available micron of processing of erosion, nanometer be micro-.Microchannel has the function of capillary force, has
Conducive to so that nano-particle solution flows into the microchannel under the action of capillary force of above-mentioned microchannel, and in it from
Assembling.
The Flexible formwork assembly 120 is polydimethylsiloxane template or polymetylmethacrylate template.But
It is not limited to above-mentioned template, others can etch the Flexible formwork assembly of the fluid channel with capillary force all in the protection model of the application
It encloses.
Specifically, as shown in Figure 1, the structure of the microchannel 121 are as follows: the channel-type structure that end communicates with the outside world.Tool
Body are as follows: end communicate with the outside world through the single of the Flexible formwork assembly bottom or the channel-type structure of a plurality of parallel interval.By
This, the structure of the microchannel of the application can according to need the change for carrying out size and shape, and microchannel is end and extraneous phase
Thorough cut channel type structure, the nano-particle solution that can be added dropwise to the end under the action of capillary force, are flowed by end
Enter in the channel-type structure in template.
Wherein, the width of the microchannel is 2.5 μm;Spacing between the microchannel is 5 μm.It is above-mentioned micro- logical as a result,
The size in road is that one kind can be suitable for that nano-particle solution flows into and in the appropriate size (microchannel of assembling wherein
Width can also be that 3 μm or 5 μm or other desired size, the spacing between the microchannel can also be 7 μ
M, 10 μm or other desired size).As shown in figure 3, wherein 122 to stay in receiving in substrate after removing Flexible formwork assembly
Structure after rice corpuscles self assembly.
Wherein, the device of the application, further includes: control appliance of temperature and humidity (not shown), it is described micro- logical for controlling
The temperature and humidity of road regional environment.The application controls microchannel regional environment by setting control appliance of temperature and humidity as a result,
Temperature humidity be suitable for the nano-particle solution evaporation, to be more advantageous to the self assembly of nanoparticle.
To sum up, the application covers Flexible formwork assembly on a planar base, and under the action of capillary force, nano-particle solution can flow
Enter in the microchannel in template, so that nanoparticle is carried out self assembly according to the structure of the microchannel in template, to secure gold
Position of the nanometer rods in substrate realizes the accurate control to self-assembly position.And the application is based on above-mentioned micro-
Channel can according to need and generate specified size, position and determine uniform self-assembly structure, overcomes existing
In technology due to the influence of " coffee ring " effect cause assembling nano particle structure it is inhomogenous, and then influence nanoparticle pair
The defect of the sensitivity of Molecular Detection.(" coffee ring " effect: in evaporation process, the contact angle of water can be always maintained at constant, radius
Become smaller;And the edge of solution can anchor at always in contact line, radius is constant, and contact angle becomes smaller.Drop is maintained in solution
Area is constant, will generate a flowing outside from center, and solute in solution is taken in contact line and deposited by this flowing
Get off, ultimately forms ring deposition object.Here it is in " coffee ring effect ").
Embodiment two
The application also provides a kind of production method of self-assembly structure, based in embodiment one for making
The device of self-assembly structure, the present invention provide a kind of production method of self-assembly structure, comprising:
S401, by nano-particle solution drop to the microchannel end (wherein, the shape and size of microchannel be can be with
Change as needed) so that under the action of capillary force of the nano-particle solution by the microchannel of the Flexible formwork assembly,
It flows into the microchannel, and carries out self assembly in the microchannel, the super crystal structure of the three-dimensional of formation rule.
S402 (makes to arrange between gold nanorods by controlling the temperature and humidity of environment to obtain uniform assembling effect
It is more regular, rather than generate random structure).
S403, it is described to remove the Flexible formwork assembly after the completion of nano-particle solution volatilization by a specified time
It removes, to obtain the three-dimensional structure of fixed self-assembly regularization on a planar base.
In conclusion the device provided by the present application for making self-assembly structure and the system based on the device
Accurate control to self-assembly position may be implemented in the method for making self-assembly structure, and can be according to need
The super crystal structure of three-dimensional of rule after generating specified size, uniform self-assembly is (micro- logical by changing
The shape and size in road).And the application by setting control appliance of temperature and humidity control microchannel regional environment temperature humidity with
It is suitable for the evaporation of the nano-particle solution, (to obtain uniform assembling effect, is made with being more advantageous to the self assembly of nanoparticle
What is arranged between gold nanorods is more regular).
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of for making the device of self-assembly structure characterized by comprising
One planar substrates;
One Flexible formwork assembly;Its bottom is bonded the upper surface for being set to the planar substrates;And the Flexible formwork assembly with it is described flat
The bottom of face substrate fitting be provided with it is communicating with the outside world, for so that the microchannel that extraneous nano-particle solution flows into.
2. the apparatus according to claim 1, which is characterized in that further include:
Control appliance of temperature and humidity, for controlling the temperature and humidity of the microchannel regional environment.
3. the apparatus according to claim 1, which is characterized in that the microchannel structure are as follows: the ditch that end communicates with the outside world
Channel type structure.
4. device according to claim 3, which is characterized in that the channel-type structure are as follows: what end communicated with the outside world passes through
Wear the single of the Flexible formwork assembly bottom or the channel-type structure of a plurality of parallel interval.
5. the device according to shown in claim 4, which is characterized in that the width of the microchannel be include, but is not limited to
Down first, 2.5 μm, 3 μm, 5 μm;
Spacing between the microchannel is following first, 5 μm, 7 μm, 10 μm to include, but is not limited to.
6. the apparatus according to claim 1, which is characterized in that the planar substrates are as follows:
Common plane sheet glass, quartzy flat glass, conductive transparent surface glass, plated film flat glass or plane silicon materials.
7. the apparatus according to claim 1, which is characterized in that the Flexible formwork assembly is polydimethylsiloxane template
Or polymetylmethacrylate template.
8. the apparatus according to claim 1, which is characterized in that the microchannel of the Flexible formwork assembly bottom is set as passing through
Soft lithograph mode handles setting.
9. a kind of production method of self-assembly structure is existed based on any one of claim 1-7 described device, feature
In, comprising:
Nano-particle solution is dropped to the end of the microchannel, so that the nano-particle solution is by the Flexible formwork assembly
It under the action of the capillary force of microchannel, flows into the microchannel, and carries out self assembly, formation rule in the microchannel
The super crystal structure of three-dimensional.
10. according to the method described in claim 9, it is characterized by further comprising:
By controlling the temperature and humidity of the microchannel regional environment, with the nanoparticle of the different shape needed for obtaining from group
Assembling structure;
The Flexible formwork assembly is removed, after the completion of nano-particle solution volatilization to obtain fixation by a specified time
The three-dimensional structure of self-assembly regularization on a planar base.
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Cited By (2)
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CN110203878A (en) * | 2019-05-27 | 2019-09-06 | 东南大学 | Single layer nano particle dimer and poly preparation based on hydrophobe array |
CN114235195A (en) * | 2021-11-18 | 2022-03-25 | 厦门大学 | Ultrahigh-space-time resolution fluid temperature sensing chip and manufacturing method thereof |
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