CN108555461A - Full-automatic non-contact laser puncher - Google Patents
Full-automatic non-contact laser puncher Download PDFInfo
- Publication number
- CN108555461A CN108555461A CN201810301483.7A CN201810301483A CN108555461A CN 108555461 A CN108555461 A CN 108555461A CN 201810301483 A CN201810301483 A CN 201810301483A CN 108555461 A CN108555461 A CN 108555461A
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- Prior art keywords
- sample
- laser
- full
- card
- cutting
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- B23K26/00—Working by laser beam, e.g. welding, cutting or boring
- B23K26/36—Removing material
- B23K26/38—Removing material by boring or cutting
- B23K26/382—Removing material by boring or cutting by boring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- B23K26/00—Working by laser beam, e.g. welding, cutting or boring
- B23K26/70—Auxiliary operations or equipment
- B23K26/702—Auxiliary equipment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
- G01N2001/2886—Laser cutting, e.g. tissue catapult
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- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Plasma & Fusion (AREA)
- Mechanical Engineering (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Laser Beam Processing (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of full-automatic non-contact laser puncheres, including:Laser, laser are used to emit the sample card of laser cutting papery.Due to the card sample using laser cutting papery, for the sample being cut by laser out without Mechanical Contact, the sample of contactless cutting is pollution-free, and especially in biochemistry, contactless CR production is safer reliable;Also, the precision higher of laser cutting, can realize automation, high-precision and efficient production.
Description
Technical field
The present invention relates to biological specimen collection card manufacture technology fields, and in particular to for producing biological specimen collection card
Full-automatic non-contact laser puncher.
Background technology
As the screening of newborn's deaf gene and HPV generaI investigations are promoted, sample is stored in the mode of prefabricated card because taking
Sample and convenient transportation operation, at the same it is of low cost, and the sample size of type of card is increasing.But existing biological sample collection card is exhausted
Most of is all to obtain sample by mechanical hole knockout, cannot be satisfied the sample size process demand of growth.
In the prior art, biological sample collection card is produced by the way of mechanical punching, be easy to cause sample pollution, and cut
Cotton-shaped clast is generated during cutting.
Invention content
The application provides a kind of free of contamination full-automatic non-contact laser puncher.
A kind of full-automatic non-contact laser puncher, including laser are provided in a kind of embodiment, the laser is used
In the sample card of transmitting laser cutting papery.
Further, laser is brief pulse UV laser device.
Further, further include galvanometer system and gripper sampling system;
Galvanometer system includes incidence end and moveable exit end, and incidence end is located in the light path of laser transmitting laser,
Moveable exit end is for controlling laser cutting path;
Gripper sampling system includes moveable manipulator, manipulator be used for by card sample capture to galvanometer system
Exit end it is opposite cutting area punching.
Further, full-automatic non-contact laser puncher further includes loading and unloading system, and loading and unloading system includes removable
Dynamic clamping box, clamping box are equipped with several card slots for clamping card sample side by side, card slot opening face along moving direction
It is arranged to manipulator.
Further, gripper sampling system further includes the linear guide, and one end of the linear guide is located at cutting zone position, separately
It is docked with clamping box one end.
Further, full-automatic non-contact laser puncher further includes camera and central processing unit, camera towards
Cutting area is arranged, and camera is used to shoot the card sample positioned at cutting area, and sends image to central processing unit, centre
Reason device is used to obtain the position of image and identification card sample, and controls positioning and the cutting track of galvanometer system exit end.
Further, full-automatic non-contact laser puncher further includes sample collecting system, and sample collecting system includes
Moveable collection box, collection box are located at the lower section of cutting area, and the collection hole for collecting sample with several arrays.
Further, there is cutting sampling area and identification code paste area on card sample.
Further, full-automatic non-contact laser puncher further includes bar code identification module, and bar code identification module is in
Central processor signal connects, the mobile route setting of bar code identification module read end face and capture card sample to manipulator, item
Code identification module is used for the identification code read on card sample and sends central processing unit to by information is read.
Further, full-automatic non-contact laser puncher further includes that automatic dust removing filters system and cooling cycle system
System, it includes dedusting absorption end that automatic dust removing, which filters system, and dedusting is adsorbed end face and is arranged to cutting area, and cooling recirculation system includes cold
But heat absorbing end, cooling heat absorbing end are arranged close to laser and cutting area.
According to the full-automatic non-contact laser puncher of above-described embodiment, due to the card sample using laser cutting papery
This, for the sample being cut by laser out without Mechanical Contact, the sample of contactless cutting is pollution-free, non-to connect especially in biochemistry
Touch CR production is safer reliable;Also, the precision higher of laser cutting, can realize automation, high-precision and height
The production of efficiency.
Description of the drawings
Fig. 1 is the positive structure diagram of full-automatic non-contact laser puncher in the present embodiment;
Fig. 2 is the local overlooking structural schematic diagram of full-automatic non-contact laser puncher in the present embodiment;
Fig. 3 is the side structure schematic view of loading and unloading system in the present embodiment;
Fig. 4 is the structure diagram of control section in the present embodiment;
Fig. 5 is the flow chart of production stage in the present embodiment.
Specific implementation mode
Below by specific implementation mode combination attached drawing, invention is further described in detail.
A kind of full-automatic non-contact laser puncher is present embodiments provided, this puncher is equipped with laser, laser
The card sample production sample of papery is cut by laser by transmitting, card sample can be dry for forensic dna trace card, FTA cards, DBS
Blood piece card or other biochemical high-throughput cards.
As shown in Figure 1, the full-automatic non-contact laser puncher of the present embodiment includes mainly laser 1, galvanometer system 2
With gripper sampling system 3.
Laser 1 is semiconductor cooling light source laser, preferably, ultraviolet (355nm) with short pulse (femtosecond) DPSS types
Laser, it is smaller to generate in material working process heat affected area with it, while having the characteristics that flexible machining control services
It is sampled in biochargeable paper quality sample, the sample of different shape and size can be obtained.In other embodiments, other can be selected
Cold light source is as cutting medium.
In the present embodiment, laser 1 is mounted on by mounting bracket 91 on pedestal 9, and mounting bracket 91 includes support plate, fixed column
And lifting column, support plate are mounted on by fixed column on pedestal 9, laser 1 is mounted on branch by the upgrading scalable adjusting of column
On fagging, scalable adjusting can be realized by screw thread and rotatable connection setting.The transmitting terminal level of laser 1 after installation is set
It sets.
Galvanometer system 2 is mounted on the transmitting terminal of laser 1.Galvanometer system 2 includes incidence end, reflective mirror, lens, outgoing
The components such as end and actuator, wherein exit end are horizontally movable setting, and actuator is connect with exit end, for driving outgoing
End moves horizontally, that is, is used to control the cutting path of laser.The incidence end of galvanometer system 2 is docked with the transmitting terminal of laser 1
It is installed together so that the incidence end of galvanometer system 2 is located at laser 1 and emits in the light path of laser.The exit end of galvanometer system 2
It is arranged vertically downward, the corresponding region in lower section of exit end is cutting area.
As shown in Fig. 2, gripper sampling system 3 includes manipulator 31, robot drives part 32 and the linear guide 33.Straight line
Guide rail 33 is vacantly mounted on pedestal 9 by support level, and one end is located at the opposite cutting area of exit end of galvanometer system 2,
The other end is docked with the clamping box of loading and unloading system, and the linear guide 33 is used for support card sample 10, in process, card sample
Originally 10 it is moved to cutting area from one end of the linear guide 33.Robot drives part 32 includes driving motor and straight-line transmitting moving axis, machine
Tool hand-drive part 32 is mounted on by holder on pedestal 9, the output end (straight-line transmitting moving axis) and manipulator of robot drives part 32
31 connections, 32 driving manipulator 31 of robot drives part capture card sample 10 along the linear guide 33 in upper and lower material position and cutting
It is alternately moved between position.Also, manipulator 31 includes clamping actuator and clamping jaw, and clamping actuator drives clamping jaw clamping card sample
This 10.In other embodiments, robot drives part 32 or cylinder, manipulator 31 are directly installed on the output shaft of cylinder
On.
As shown in figure 3, in the present embodiment, full-automatic non-contact laser puncher further includes loading and unloading system 4, loading and unloading
System 4 includes lifting support 41, clamping box 42 and lifting actuator 43.Lifting actuator 43 is vertically installed on pedestal 9, is lifted
Holder 41 is mounted on lifting actuator 43, and lifting actuator 43 drives lifting support 41 along Z axis lifting moving, clamping box 42
Clamping is detachably arranged on lifting support 41.
Specifically, lifting support 41 includes lower baffle plate, overhead gage and side plate, clamping box 42 are connected to lower baffle plate and overhead gage
Between, in order to preferably position fixed clamping box 42, it is inlaid with magnet respectively in the upper and lower ends of side plate, it is opposite in clamping box 42
Face be equipped with can be magnetic metal so that clamping box 42 are fixed on by magnetic on lifting support 41.
Clamping box 42 are the vertical strip babinet that side has opening, and the opening of clamping box 42 is arranged towards manipulator 31,
And it is docked with the linear guide 33.Alongst (i.e. moving direction) is equipped with several card slots side by side to clamping box 42, each
Card slot is for clamping a card sample 10, in order to which all card samples 10 are located in clamping box 42, i.e., all cards
Sample 10 is aligned in vertical direction, is equipped with vertical positioning strip in the bottom of clamping box 42, card sample 10 is inserted into card slot
Until being contacted with positioning strip, completes positioning and clamp.The side of clamping box 42 is also equipped with handle, the dismounting of box 42 easy to setup.
In the present embodiment, full-automatic non-contact laser puncher further includes camera 5 and central processing unit 6, camera 5
On pedestal 9, camera 5 is arranged towards cutting area, and camera 5 is used to shoot positioned at cutting area card sample to be cut
10, camera 5 is connect with 6 signal of central processing unit, and the image that camera 5 is shot sends central processing unit 6, central processing unit to
6 also connect with the actuator of galvanometer system 2, and central processing unit 6 is by the image of acquisition by the way that the position of card sample 10 is calculated
Coordinate is set, the actuator driving exit end that galvanometer system 2 is controlled in conjunction with pre-stored cutting track program moves horizontally cutting
Go out sample.
In the present embodiment, full-automatic non-contact laser puncher further includes sample collecting system 7, sample collecting system 7
Including collection box 71 and actuator 72 is collected, actuator 72 is collected and is mounted on pedestal 9, it includes X-axis and Y-axis to collect actuator 72
The guide rail and actuator in direction, collection box 71, which is mounted on, collects on actuator 72, and positioned at the lower section of cutting area, that is, is located at straight line
The lower section of guide rail 33.Collection box 71 is equipped with several collection holes, and the planar movement of collection box 71 can be driven by collecting actuator 72,
So that the sample that the collection hole alignment cutting area of collection box 71 is cut.Specifically, collection box 71 include collecting board, locating piece,
Fixed plate and mounting assembly, collecting board are the sample reception PCR plate in 96 holes or the sample reception deep-well plates in 96 holes, and collection box 71 can
According to the type and size of the size selection collecting board of cutting sample.
As shown in Fig. 2, card sample 10 includes cutting area 10a and identification code paste area 10b, cutting area 10a is for cutting
Go out sample, identification code paste area 10b is used to paste the bar code or Quick Response Code of 10 information of identification card sample.In the linear guide 33
Above and below be separately installed with a bar code identification module 8, the scanning of bar code identification module 8 reads end face to the linear guide
33 settings, i.e. bar code identification module 8 can be scanned across the card sample 10 of the linear guide 33, read the information of card sample 10,
Bar code identification module 8 is connect with 6 signal of central processing unit, sends the information of reading to card sample 10, central processing unit 6
The type that card sample 10 is identified according to the information of the card sample 10 of acquisition is cut into correspondingly-sized to control galvanometer system 2
The sample of size.
In the present embodiment, full-automatic non-contact laser puncher further includes that automatic dust removing filters system and cooling cycle system
System (not shown), it includes dedusting absorption end and dedusting actuator that automatic dust removing, which filters system, and dedusting actuator is that vacuum is inhaled
Attached pump or dedusting actuator are wind turbine, and dedusting absorption end is connect with dedusting actuator, and dedusting actuator is set towards cutting area
Set, for adsorbing the dust and clast that are generated in cutting process, to safeguard the cleaning of puncher, effectively prevent dust and clast into
Entering to components interior influences production precision.
Cooling recirculation system includes heat absorbing end and heat exchanger, and heat absorbing end is connect by pipeline with heat exchanger, heat absorption end face to
Laser 1 and cutting area setting, two heat sources of the heat absorbing end on puncher, to reduce the temperature of complete machine.
In the present embodiment, full-automatic non-contact laser puncher further includes casing, and casing is mounted on pedestal 9, casing
The all components on pedestal 9 are wrapped, a closed processing environment is enclosed, automatic dust removing is also improved and filters system
Dust removing effects and cooling recirculation system cooling effect.
As shown in figure 4, central processing unit 6 respectively with camera 5, bar code identification module 8, control galvanometer system 2 in drive
Moving part, robot drives part 32, the clamping actuator on manipulator 31, lifting actuator 43 and collection 72 signal of actuator connect
It connects, central processing unit 6 controls the automation punching production of entire puncher.
As shown in figure 5, the production stage of the puncher of the present embodiment is as follows:
S001:Feeding;
Manually several card samples 10 are put into clamping box 42, then the clamping box 42 for filling card sample 10 are blocked
On lifting support 41, and absorption is positioned by magnet and is fixed.
Lifting actuator 43 drives lifting support 41 that clamping box 42 is driven to be moved to material position, waits for the crawl card of manipulator 31
Piece sample 10.Wherein, upper material position is that the card sample 10 of 42 the top of clamping box is aligned with manipulator 31.
S002:Capture card sample;
32 driving manipulator 31 of robot drives part is moved to upper material position along the linear guide 33 and captures card sample 10.
S003:Information is read;
Manipulator 31 captures card sample 10 and is moved to cutting area along the linear guide 33, passes through bar code in the process and identifies mould
8 cog region of block, bar code identification module 8 scans the bar code information on card sample 10, and sends central processing unit 6, centre to
It manages device 6 and corresponding machining locus is selected according to the information of acquisition.
S004:Cutting positioning;
Manipulator 31 captures card sample 10 and is moved to cutting area, and camera 5 is taken pictures, and image is sent to center
Processor 6, central processing unit 6 calculate the accurate coordinates of card sample 10 according to image, adjust the initial manufacture of galvanometer system 2
Position.
S005:Cutting production;
After positioning, laser 1 emits laser, the actuator control exit end movement of galvanometer system 2 so that laser installation is pre-
If track is cut into sample on card sample 10.The sample being cut into directly is fallen into the collection box 71 of lower section.
In lasting process, galvanometer system 2 need to be repositioned repeatedly, collect actuator 72 and collection box 71 is also driven to move
It moves to corresponding collection position and collects the sample that cutting is fallen.
S006:Blanking.
After card sample 10 has been cut, the crawl of card sample 10 after cutting is moved back to clamping box 42 by manipulator 31
In card slot, lifting actuator 43 drives lifting support 41 that clamping box 42 is driven up to move a lattice so that second card sample
10, which are moved to the standby tool hand 31 of material position, captures.
It repeats above-mentioned steps and cuts second card sample 10, and so on, it realizes that automatic laser is contactless and cuts
Production is cut, automatic dust removing is run during processing simultaneously and filters system and cooling recirculation system, ensures that complete machine is clean and prevents high temperature
Influence machining accuracy.
Full-automatic non-contact laser puncher provided in this embodiment, due to being cut by laser the card of papery using cold light source
Piece sample 10, for the sample being cut by laser out without Mechanical Contact, the sample of contactless cutting is pollution-free, is especially led in biochemistry
Domain, contactless CR production are safer reliable;Also, galvanometer system 2 controls laser by moveable exit end
Cutting path, gripper sampling system 3 quickly capture card sample 10 by moveable manipulator 31, have efficient automatic
Change production capacity, realizes unattended automatic sampling processing, greatly saved cost.
Specifically, this full-automatic non-contact laser puncher is due to the use of laser cutting (220V alternating currents), single sample
Cut duration<1s is used, safety non-pollution without additional consumptive material.Galvanometer system 2 provides hi-precision cutting template, cuts sample
Dimensional accuracy can not change hardware configuration up to 0.05mm, and different dimensions templates are arranged using software, behaviour
After sample is put into sample introduction tank by work person, you can realize unattended automatic sampling.
Use above specific case is illustrated the present invention, is merely used to help understand the present invention, not limiting
The system present invention.For those skilled in the art, according to the thought of the present invention, can also make several simple
It deduces, deform or replaces.
Claims (10)
1. a kind of full-automatic non-contact laser puncher, which is characterized in that including laser, the laser is sharp for emitting
Light cuts the sample card of papery.
2. full-automatic non-contact laser puncher as described in claim 1, which is characterized in that the laser is short pulse
Ultraviolet laser.
3. full-automatic non-contact laser puncher as claimed in claim 1 or 2, which is characterized in that further include galvanometer system
With gripper sampling system;
The galvanometer system includes incidence end and moveable exit end, and the incidence end is located at laser transmitting laser
In light path, the moveable exit end is for controlling laser cutting path;
The gripper sampling system includes moveable manipulator, the manipulator be used for by card sample capture to it is described
The cutting area that the exit end of galvanometer system is opposite punches.
4. full-automatic non-contact laser puncher as claimed in claim 3, which is characterized in that further include loading and unloading system,
The loading and unloading system includes moveable clamping box, the clamping box along moving direction be equipped with several side by side for clamping
The card slot of card sample, the card slot opening are arranged towards the manipulator.
5. full-automatic non-contact laser puncher as claimed in claim 4, which is characterized in that the gripper sampling system
Further include the linear guide, one end of the linear guide is located at cutting zone position, and the other end is docked with the clamping box.
6. full-automatic non-contact laser puncher as claimed in claim 4, which is characterized in that further include camera and center
Processor, the camera are arranged towards cutting area, and the camera is used to shoot the card sample positioned at cutting area, and will figure
As sending the central processing unit to, the central processing unit is used to obtain the position of described image and identification card sample, and
Control positioning and the cutting track of the galvanometer system exit end.
7. full-automatic non-contact laser puncher as claimed in claim 4, which is characterized in that further include sample collection system
System, the sample collecting system includes moveable collection box, and the collection box is located at the lower section of the cutting area, and if having
The collection hole for collecting sample of dry array.
8. full-automatic non-contact laser puncher as claimed in claim 5, which is characterized in that have on the card sample
Cutting sampling area and identification code paste area.
9. full-automatic non-contact laser puncher as claimed in claim 8, which is characterized in that further include bar code identification mould
Block, the bar code identification module are connect with central processing unit signal, and the reading end face of the bar code identification module is to the machinery
Hand captures the mobile route setting of card sample, and the bar code identification module is used to read the identification code on card sample and will
It reads information and sends the central processing unit to.
10. full-automatic non-contact laser puncher as claimed in claim 4, which is characterized in that further include that automatic dust removing is taken out
Filter system and cooling recirculation system, it includes dedusting absorption end that the automatic dust removing, which filters system, and the dedusting adsorbs end face to cutting
Area's setting is cut, the cooling recirculation system includes cooling heat absorbing end, and the cooling heat absorbing end is arranged close to laser and cutting area.
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CN201810301483.7A CN108555461A (en) | 2018-04-04 | 2018-04-04 | Full-automatic non-contact laser puncher |
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CN110369876A (en) * | 2019-08-02 | 2019-10-25 | 戴林涛 | Auxiliary device based on femtosecond laser processing |
CN110560930A (en) * | 2019-09-16 | 2019-12-13 | 深圳泰软软件科技有限公司 | Cutting method and device for blood spot of blood sampling card and readable storage medium |
CN110763263A (en) * | 2019-10-28 | 2020-02-07 | 青岛歌尔微电子研究院有限公司 | Dustproof structure and manufacturing method thereof |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110369876A (en) * | 2019-08-02 | 2019-10-25 | 戴林涛 | Auxiliary device based on femtosecond laser processing |
CN110560930A (en) * | 2019-09-16 | 2019-12-13 | 深圳泰软软件科技有限公司 | Cutting method and device for blood spot of blood sampling card and readable storage medium |
CN110560930B (en) * | 2019-09-16 | 2021-11-16 | 深圳泰软软件科技有限公司 | Cutting method and device for blood spot of blood sampling card and readable storage medium |
CN110763263A (en) * | 2019-10-28 | 2020-02-07 | 青岛歌尔微电子研究院有限公司 | Dustproof structure and manufacturing method thereof |
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