CN108451831A - Pregnant woman's moisturizing and nourishing smoothing toner and preparation method thereof - Google Patents
Pregnant woman's moisturizing and nourishing smoothing toner and preparation method thereof Download PDFInfo
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- CN108451831A CN108451831A CN201810484150.2A CN201810484150A CN108451831A CN 108451831 A CN108451831 A CN 108451831A CN 201810484150 A CN201810484150 A CN 201810484150A CN 108451831 A CN108451831 A CN 108451831A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
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Abstract
Pregnant woman's moisturizing and nourishing smoothing toner of the present invention, is prepared from the following raw materials in parts by weight:18 parts of dipropylene glycol, 0.1 1 parts of tamarind seed extract, 0 10 parts of glycerine, 0.02 0.6 parts of allantoin, 0.2 4 parts of reed fragrant plant glue oil, 0.1 8 parts of purslane extract, 0.02 0.6 parts of dipotassium glycyrrhizinate, decoyl hydroximic acid, 1,2 hexylene glycols, 1, totally 0.4 3 parts of 3 propylene glycol threes, 80 98 parts of water.The beneficial effects of the invention are as follows, the product not spirituosity, the substance of potent replenishing water and preserving moisture is added in smoothing toner, skin moisture can be supplemented rapidly, the effect of reaching well to face skin replenishing water and preserving moisture, and have both desalination wrinkle of skin, enhancing skin elasticity, exclude the effect of skin toxin, Cucumber Extract, while not stimulating skin of face, after use without rub with the hands mud, it is tight phenomena such as.The product can also decompose greasy dirt on the face, prevent fat granule etc..
Description
Technical field
The invention belongs to skin care fields, are related to a kind of pregnant woman's moisturizing and nourishing smoothing toner and preparation method thereof.
Background technology
It is influenced since modern people's rhythm of life is fast, and by various environment, frequent dry, the intensely dark pool of skin.Mesh
Smoothing toner on preceding Cosmetic Market is largely containing preservative, fungicide, fragrance, synthetic dyestuff, ethyl alcohol etc., and consumer is in length
After phase uses such product, being irritating to the skin property and other adverse reactions, skin will appear allergic reaction or pigment deposition, more
It is serious or even Other diseases or function and effect unobvious can be induced.It causes great trouble for consumer, makes simultaneously
The consumer of most skin sensitivity dare not use smoothing toner skin care.Especially pregnant and perinatal period women, in terms of using skin care item
Even more there are many misgivings.
Invention content
In order to compensate for the shortcomings of the prior art, the present invention provides a kind of pregnant woman's use that is safe and reliable, being capable of replenishing water and preserving moisture
Moisturizing and nourishing smoothing toner and preparation method thereof.
The present invention is achieved through the following technical solutions:
Pregnant woman's moisturizing and nourishing smoothing toner of the present invention, it is characterised in that:It is prepared from the following raw materials in parts by weight:Dipropylene glycol
1-8 parts, 0.1-1 parts of tamarind seed extract, 0-10 parts of glycerine, 0.02-0.6 parts of allantoin, 0.2-4 parts of reed fragrant plant glue oil, purslane
0.1-8 parts of extract, 0.02-0.6 parts of dipotassium glycyrrhizinate, decoyl hydroximic acid, 1,2 hexylene glycols, 1, the 3 total 0.4- of propylene glycol three
3 parts, 80-98 parts of water.
Pregnant woman's moisturizing and nourishing smoothing toner of the present invention, is prepared from the following raw materials in parts by weight:1-5 parts of dipropylene glycol,
0.1-0.3 parts of tamarind seed extract, 0-8 parts, allantoin 0.02-0.2 of glycerine, 0.2-2 parts of reed fragrant plant glue oil, purslane extract
0.1-5 parts, 0.02-0.2 parts of dipotassium glycyrrhizinate, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol threes are 0.4-1 parts total, water
80-98 parts.
The weight ratio of decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol threes is:(2-4):(8-10):(5-7).
The preparation method of pregnant woman's moisturizing and nourishing smoothing toner of the present invention, it is characterised in that:Include the following steps:
(1)Dipropylene glycol is mixed evenly with dispersion tamarind seed extract, sequentially adds water and allantoin, stirs evenly, adds
Heat sterilizes 8-13 minutes to 85-95 DEG C;
(2)It is cooled to 40-50 DEG C, reed fragrant plant glue oil, purslane extract and dipotassium glycyrrhizinate is added, is stirred until homogeneous;
(3)It is cooled to 34-42 DEG C, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol are added, stir evenly;
(4)It is qualified to examine, and is filled into smoothing toner Packaging Bottle, packs.
Step(1)In:Dipropylene glycol and glycerine are mixed evenly with dispersion tamarind seed extract, sequentially add water and urine
Bursin stirs evenly, and is heated to 85-95 DEG C, sterilizes 8-13 minutes.
Step(1)In, 90 DEG C are heated to, is sterilized 10 minutes.
Step(2)In, it is cooled to 45 DEG C.
Step(3)In, it is cooled to 38 DEG C.
Tamarind seed extract, purslane extract are alcohol extracting thing.Purslane, tamarind seed crush respectively, sieving,
Then the solvent of 10-20 times of plant weight is added, wherein solvent is the ethyl alcohol that volumetric concentration is 75%-85%, then in 35-45
It is impregnated 7-9 hours under the conditions of DEG C, carries out low temperature ultrasonic and extract 5-7 hours, supernatant centrifugation, filtering, refluxing ethanol are taken, most afterwards through two
After secondary filtering, you can obtain natural plant ingredient.
The invention has the advantages that the product not spirituosity, adds the substance of potent replenishing water and preserving moisture in smoothing toner, it can
Rapid supplement skin moisture the effect of reaching well to face skin replenishing water and preserving moisture, and has both desalination wrinkle of skin, enhancing skin
Skin elasticity excludes the effect of skin toxin, Cucumber Extract, while not stimulating skin of face, existing without mud, tight etc. is rubbed with the hands after use
As.The product can also decompose greasy dirt on the face, prevent fat granule etc..The manufacturing method of the present invention is simple, low energy consumption, week
Phase is short, is suitble to mass production, cost-effective, is suitble to produce in enormous quantities.
This product takes natural origin to nourish ingredient, contains tamarind seed, purslane extraction essence, coordinates high moisturizing ingredient reed fragrant plant
Glue oil reinforces skin resist drying ability, and moment supplements skin moisture, and pregnant and perinatal period women skin water profit bullet is made to slide.
It is formulated no added:Preservative free, without essence, non-mineral oil, without animal oil, prosthetic pigment, it is alcohol-free, without a huge sum of money
Belong to, without hormone.The product is nontoxic, without side-effects, securely and reliably, numerous women is suitble to use, and also is adapted for pregnant and perinatal period women use.
Decoyl hydroximic acid, 1,2 hexylene glycols, 1, non-traditional preservative of the 3 propylene glycol compounding with anti-corrosion function, Ke Yixuan
Claim preservative free formula.
Specific implementation mode
Embodiment 1
Pregnant woman's moisturizing and nourishing smoothing toner of the present invention, is made of the raw material of following weight:1 kilogram of dipropylene glycol, tamarind seed carries
0.1 kilogram of object is taken, 0.5 kilogram of glycerine, 0.02 kilogram of allantoin, 0.2 kilogram of reed fragrant plant glue oil, 0.1 kilogram of purslane extract is sweet
0.02 kilogram of oxalic acid dipotassium, decoyl hydroximic acid, 1,2 hexylene glycols, 1, totally 0.4 kilogram of 3 propylene glycol threes, 90 kilograms of water.
The weight ratio of decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol threes is:2:10:5.
Pregnant woman's preparation method of moisturizing and nourishing smoothing toner of the present invention, includes the following steps:
(1)Dipropylene glycol, glycerine and dispersion tamarind seed extract are mixed evenly, and sequentially add water and allantoin, and stirring is equal
It is even, 85 DEG C are heated to, is sterilized 13 minutes;
(2)40 DEG C are cooled to, reed fragrant plant glue oil, purslane extract and dipotassium glycyrrhizinate is added, is stirred until homogeneous;
(3)34 DEG C are cooled to, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol are added, stir evenly;
(4)It is qualified to examine, and is filled into smoothing toner Packaging Bottle, packs.
Embodiment 2
Pregnant woman's moisturizing and nourishing smoothing toner of the present invention, is made of the raw material of following weight:8 kilograms of dipropylene glycol, tamarind seed carries
Take 1 kilogram of object, 10 kilograms of glycerine, 0.6 kilogram of allantoin, 4 kilograms of reed fragrant plant glue oil, 8 kilograms of purslane extract, dipotassium glycyrrhizinate
0.6 kilogram, decoyl hydroximic acid, 1,2 hexylene glycols, 1, totally 3 kilograms of 3 propylene glycol threes, 98 kilograms of water.
The weight ratio of decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol threes is:4:8:7.
Pregnant woman's preparation method of moisturizing and nourishing smoothing toner of the present invention, includes the following steps:
(1)Dipropylene glycol, glycerine and dispersion tamarind seed extract are mixed evenly, and sequentially add water and allantoin, and stirring is equal
It is even, 95 DEG C are heated to, is sterilized 8 minutes;
(2)50 DEG C are cooled to, reed fragrant plant glue oil, purslane extract and dipotassium glycyrrhizinate is added, is stirred until homogeneous;
(3)42 DEG C are cooled to, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol are added, stir evenly;
(4)It is qualified to examine, and is filled into smoothing toner Packaging Bottle, packs.
Embodiment 3
Pregnant woman's moisturizing and nourishing smoothing toner of the present invention, is made of the raw material of following weight.
。
The weight ratio of decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol threes is:3:9:6.
Pregnant woman's preparation method of moisturizing and nourishing smoothing toner of the present invention, includes the following steps:
(1)Dipropylene glycol, glycerine and dispersion tamarind seed extract are mixed evenly, and sequentially add water and allantoin, and stirring is equal
It is even, 90 DEG C are heated to, is sterilized 10 minutes;
(2)45 DEG C are cooled to, reed fragrant plant glue oil, purslane extract and dipotassium glycyrrhizinate is added, is stirred until homogeneous;
(3)38 DEG C are cooled to, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol are added, stir evenly;
(4)It is qualified to examine, and is filled into smoothing toner Packaging Bottle, packs.
Embodiment 4
Pregnant woman's moisturizing and nourishing smoothing toner of the present invention, is made of the raw material of following weight:3 kilograms of dipropylene glycol, tamarind seed carries
0.2 kilogram of object is taken, 0.1 kilogram of allantoin, reed fragrant plant glue is 1 kilogram oily, 3 kilograms of purslane extract, 0.1 kilogram of dipotassium glycyrrhizinate,
Decoyl hydroximic acid, 1,2 hexylene glycols, 1, totally 0.7 kilogram of 3 propylene glycol threes, 94 kilograms of water.
The weight ratio of decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol threes is:3:9:6.
Pregnant woman's preparation method of moisturizing and nourishing smoothing toner of the present invention, includes the following steps:
(1)Dipropylene glycol is mixed evenly with dispersion tamarind seed extract, sequentially adds water and allantoin, stirs evenly, adds
Heat sterilizes 11 minutes to 88 DEG C;
(2)43 DEG C are cooled to, reed fragrant plant glue oil, purslane extract and dipotassium glycyrrhizinate is added, is stirred until homogeneous;
(3)36 DEG C are cooled to, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol are added, stir evenly;
(4)It is qualified to examine, and is filled into smoothing toner Packaging Bottle, packs.
5 compliance test result of embodiment
Experiment to the skin moisturization of human skin:By 100 ages between 25-45 Sui, dry skin women at
People is divided into two groups(Selection is without allergic reaction person), and them is allowed to be used respectively by the embodiment 1-4 plant component preparations prepared
Moisturizing and nourishing smoothing toner and certain the brand moisturizing smoothing toner bought on the market(Embodiment as a comparison), smoothing toner is applied to face
Surrounding is used continuously once a day in portion.Before the use, the control for being 40% in 25 DEG C of constant temperature and relative humidity with skinanalysis apparatus
Moisture of skin is measured under the conditions of system using as reference, after beginning to use one week, two weeks and four weeks, and suspends use after three weeks,
Moisture of skin is measured, the results are shown in table below.
。
Statistics indicate that based on the numerical value measured with skinanalysis apparatus before experiment, after using the predetermined time, moisture of skin is aobvious
Work increases.For opposite Mr. Yu's brand moisturizing smoothing toner, the moisturizing and nourishing skin softening water meter containing plant component of the present invention preparation
Reveal the increase rate of bigger.Moreover, even if being used after three weeks in pause, the moisturizing and nourishing smoothing toner that plant component of the present invention is prepared
Comparable moisture of skin after a week is still kept and begins to use, this shows after stopping using smoothing toner, natural plant of the present invention
Moisture of skin can be kept whithin a period of time at the moisturizing and nourishing smoothing toner of assignment system.
Using the tester of the smoothing toner of the present invention, itches or the senses of discomfort such as cusalgia without disturbing at test, show the cosmetics pair
Skin is mildly nonirritant, and after being applied to skin of face, no stranding mud phenomenon is not tight, is comfortable on, and skin of face is relatively using preceding bright
Aobvious more smooth tender, the effect in terms of preventing dry skin dehydration, increasing skin elasticity, the reduction dry line of skin is obviously excellent
In control group.
Conclusion:The smoothing toner of the present invention can prevent dry skin to be dehydrated, increase the bullet of skin effectively to skin replenishing water and preserving moisture
Property, it is tender to play protection skin gloss.
Claims (8)
1. a kind of pregnant woman moisturizing and nourishing smoothing toner, it is characterised in that:It is prepared from the following raw materials in parts by weight:Dipropylene glycol 1-
8 parts, 0.1-1 parts of tamarind seed extract, 0-10 parts of glycerine, 0.02-0.6 parts of allantoin, 0.2-4 parts of reed fragrant plant glue oil, Herba portulacae carries
Take 0.1-8 parts of object, 0.02-0.6 parts of dipotassium glycyrrhizinate, decoyl hydroximic acid, 1,2 hexylene glycols, 1, the 3 total 0.4-3 of propylene glycol three
Part, 80-98 parts of water.
2. pregnant woman according to claim 1 moisturizing and nourishing smoothing toner, it is characterised in that:By the raw material of following parts by weight
It is made:1-5 parts of dipropylene glycol, 0.1-0.3 parts of tamarind seed extract, 0-8 parts, allantoin 0.02-0.2 of glycerine, reed fragrant plant glue oil
0.2-2 parts, 0.1-5 parts of Herba portulacae extract, 0.02-0.2 parts of dipotassium glycyrrhizinate, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 third
Glycol three is 0.4-1 parts total, 80-98 parts of water.
3. pregnant woman according to claim 1 moisturizing and nourishing smoothing toner, it is characterised in that:Decoyl hydroximic acid, 1,2 oneself two
The weight ratio of alcohol, 1,3 propylene glycol threes is:(2-4):(8-10):(5-7).
4. a kind of preparation method of pregnant woman described in claim 1 moisturizing and nourishing smoothing toner, it is characterised in that:Including following step
Suddenly:
(1)Dipropylene glycol is mixed evenly with dispersion tamarind seed extract, sequentially adds water and allantoin, stirs evenly, adds
Heat sterilizes 8-13 minutes to 85-95 DEG C.
(2)It is cooled to 40-50 DEG C, reed fragrant plant glue oil, purslane extract and dipotassium glycyrrhizinate is added, is stirred until homogeneous.
(3)It is cooled to 34-42 DEG C, decoyl hydroximic acid, 1,2 hexylene glycols, 1,3 propylene glycol are added, stir evenly.
(4)It is qualified to examine, and is filled into smoothing toner Packaging Bottle, packs.
5. the pregnant woman according to claim 4 preparation method of moisturizing and nourishing smoothing toner, it is characterised in that:Step(1)In:
Dipropylene glycol and glycerine are mixed evenly with dispersion tamarind seed extract, sequentially add water and allantoin, stir evenly, heat
To 85-95 DEG C, sterilize 8-13 minutes.
6. the preparation method of pregnant woman's moisturizing and nourishing smoothing toner according to claim 5 or 4, it is characterised in that:Step(1)
In, 90 DEG C are heated to, is sterilized 10 minutes.
7. the pregnant woman according to claim 4 preparation method of moisturizing and nourishing smoothing toner, it is characterised in that:Step(2)In,
It is cooled to 45 DEG C.
8. the pregnant woman according to claim 4 preparation method of moisturizing and nourishing smoothing toner, it is characterised in that:Step(3)In,
It is cooled to 38 DEG C.
Priority Applications (1)
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CN201810484150.2A CN108451831A (en) | 2018-05-19 | 2018-05-19 | Pregnant woman's moisturizing and nourishing smoothing toner and preparation method thereof |
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CN201810484150.2A CN108451831A (en) | 2018-05-19 | 2018-05-19 | Pregnant woman's moisturizing and nourishing smoothing toner and preparation method thereof |
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CN201810484150.2A Pending CN108451831A (en) | 2018-05-19 | 2018-05-19 | Pregnant woman's moisturizing and nourishing smoothing toner and preparation method thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109602690A (en) * | 2018-12-28 | 2019-04-12 | 上海萧雅生物科技股份有限公司 | Available skin softening water composition of pregnant woman and preparation method thereof |
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CN102920646A (en) * | 2012-10-29 | 2013-02-13 | 皖南医学院 | Nourishing moisture-retention emulsion and preparation method thereof |
CN104983609A (en) * | 2015-06-11 | 2015-10-21 | 珀莱雅化妆品股份有限公司 | Spraying type mask and preparation method thereof |
CN105342925A (en) * | 2015-12-01 | 2016-02-24 | 青岛新中新新材料有限公司 | Nourishing and moisturizing lotion |
CN105943491A (en) * | 2016-06-29 | 2016-09-21 | 广州市巧美化妆品有限公司 | Moistening and moisturizing essence and preparation method thereof |
CN106821773A (en) * | 2017-04-17 | 2017-06-13 | 诺斯贝尔化妆品股份有限公司 | A kind of skin care spraying of high-efficient atomizing |
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2018
- 2018-05-19 CN CN201810484150.2A patent/CN108451831A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102920646A (en) * | 2012-10-29 | 2013-02-13 | 皖南医学院 | Nourishing moisture-retention emulsion and preparation method thereof |
CN104983609A (en) * | 2015-06-11 | 2015-10-21 | 珀莱雅化妆品股份有限公司 | Spraying type mask and preparation method thereof |
CN105342925A (en) * | 2015-12-01 | 2016-02-24 | 青岛新中新新材料有限公司 | Nourishing and moisturizing lotion |
CN105943491A (en) * | 2016-06-29 | 2016-09-21 | 广州市巧美化妆品有限公司 | Moistening and moisturizing essence and preparation method thereof |
CN106821773A (en) * | 2017-04-17 | 2017-06-13 | 诺斯贝尔化妆品股份有限公司 | A kind of skin care spraying of high-efficient atomizing |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109602690A (en) * | 2018-12-28 | 2019-04-12 | 上海萧雅生物科技股份有限公司 | Available skin softening water composition of pregnant woman and preparation method thereof |
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Application publication date: 20180828 |