CN116549323A - Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof - Google Patents
Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof Download PDFInfo
- Publication number
- CN116549323A CN116549323A CN202310598751.7A CN202310598751A CN116549323A CN 116549323 A CN116549323 A CN 116549323A CN 202310598751 A CN202310598751 A CN 202310598751A CN 116549323 A CN116549323 A CN 116549323A
- Authority
- CN
- China
- Prior art keywords
- skin
- emollient
- acne
- extract
- oiled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 63
- 206010000496 acne Diseases 0.000 title claims abstract description 63
- 239000006071 cream Substances 0.000 title claims abstract description 47
- 238000002360 preparation method Methods 0.000 title claims abstract description 25
- 210000003205 muscle Anatomy 0.000 title claims abstract description 22
- 239000003974 emollient agent Substances 0.000 claims abstract description 91
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 50
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 49
- 230000003750 conditioning effect Effects 0.000 claims abstract description 48
- 239000000284 extract Substances 0.000 claims abstract description 41
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 229940059958 centella asiatica extract Drugs 0.000 claims abstract description 9
- 244000125300 Argania sideroxylon Species 0.000 claims abstract description 7
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 7
- 230000003255 anti-acne Effects 0.000 claims abstract description 6
- 239000009188 angelicae sinensis extract Substances 0.000 claims abstract description 5
- WNIFXKPDILJURQ-JKPOUOEOSA-N octadecyl (2s,4as,6ar,6as,6br,8ar,10s,12as,14br)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1h-picene-2-carboxylate Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@](C(=O)OCCCCCCCCCCCCCCCCCC)(C)C[C@H]5C4=CC(=O)[C@@H]3[C@]21C WNIFXKPDILJURQ-JKPOUOEOSA-N 0.000 claims abstract description 5
- WNIFXKPDILJURQ-UHFFFAOYSA-N stearyl glycyrrhizinate Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C)CCC(C(=O)OCCCCCCCCCCCCCCCCCC)(C)CC5C4=CC(=O)C3C21C WNIFXKPDILJURQ-UHFFFAOYSA-N 0.000 claims abstract description 5
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims abstract description 4
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims abstract description 4
- 229940036350 bisabolol Drugs 0.000 claims abstract description 4
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims abstract description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 48
- 239000003921 oil Substances 0.000 claims description 26
- 238000003756 stirring Methods 0.000 claims description 26
- 235000019198 oils Nutrition 0.000 claims description 25
- 235000001014 amino acid Nutrition 0.000 claims description 24
- 238000010438 heat treatment Methods 0.000 claims description 24
- 239000000463 material Substances 0.000 claims description 24
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 18
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 17
- 235000004433 Simmondsia californica Nutrition 0.000 claims description 16
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 16
- 239000011701 zinc Substances 0.000 claims description 16
- 229910052725 zinc Inorganic materials 0.000 claims description 16
- 150000001413 amino acids Chemical class 0.000 claims description 15
- 239000003963 antioxidant agent Substances 0.000 claims description 15
- 239000002131 composite material Substances 0.000 claims description 15
- 230000003078 antioxidant effect Effects 0.000 claims description 14
- 239000002245 particle Substances 0.000 claims description 13
- 235000020238 sunflower seed Nutrition 0.000 claims description 13
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 12
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 12
- 238000001914 filtration Methods 0.000 claims description 12
- 239000011732 tocopherol Substances 0.000 claims description 12
- 229930003799 tocopherol Natural products 0.000 claims description 12
- 235000010384 tocopherol Nutrition 0.000 claims description 12
- 229960001295 tocopherol Drugs 0.000 claims description 12
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 12
- -1 cetyl ethyl Chemical group 0.000 claims description 11
- 239000002562 thickening agent Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 8
- 238000001035 drying Methods 0.000 claims description 8
- 239000008169 grapeseed oil Substances 0.000 claims description 8
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical group CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 8
- ONDPHDOFVYQSGI-UHFFFAOYSA-N zinc nitrate Chemical compound [Zn+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ONDPHDOFVYQSGI-UHFFFAOYSA-N 0.000 claims description 8
- 235000016108 Argania sideroxylon Nutrition 0.000 claims description 6
- 240000000902 Diospyros discolor Species 0.000 claims description 6
- 235000003115 Diospyros discolor Nutrition 0.000 claims description 6
- 235000001950 Elaeis guineensis Nutrition 0.000 claims description 6
- 244000127993 Elaeis melanococca Species 0.000 claims description 6
- 244000068988 Glycine max Species 0.000 claims description 6
- 235000010469 Glycine max Nutrition 0.000 claims description 6
- 235000013399 edible fruits Nutrition 0.000 claims description 6
- 150000002148 esters Chemical class 0.000 claims description 6
- 239000002540 palm oil Substances 0.000 claims description 6
- 239000003549 soybean oil Substances 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims description 5
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims description 5
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims description 5
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 5
- 239000004472 Lysine Substances 0.000 claims description 5
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims description 5
- 240000001717 Vaccinium macrocarpon Species 0.000 claims description 5
- 235000012545 Vaccinium macrocarpon Nutrition 0.000 claims description 5
- 235000002118 Vaccinium oxycoccus Nutrition 0.000 claims description 5
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 claims description 5
- 235000003704 aspartic acid Nutrition 0.000 claims description 5
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims description 5
- 238000004140 cleaning Methods 0.000 claims description 5
- 235000004634 cranberry Nutrition 0.000 claims description 5
- 238000001514 detection method Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 241000628997 Flos Species 0.000 claims description 4
- 239000004471 Glycine Substances 0.000 claims description 4
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims description 4
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims description 4
- 240000007472 Leucaena leucocephala Species 0.000 claims description 4
- 235000010643 Leucaena leucocephala Nutrition 0.000 claims description 4
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims description 4
- 235000004279 alanine Nutrition 0.000 claims description 4
- SHZIWNPUGXLXDT-UHFFFAOYSA-N caproic acid ethyl ester Natural products CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 claims description 4
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 4
- 229940032094 squalane Drugs 0.000 claims description 4
- 229910001220 stainless steel Inorganic materials 0.000 claims description 4
- 239000010935 stainless steel Substances 0.000 claims description 4
- 239000004474 valine Substances 0.000 claims description 4
- UGZADUVQMDAIAO-UHFFFAOYSA-L zinc hydroxide Chemical compound [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 claims description 4
- 229940007718 zinc hydroxide Drugs 0.000 claims description 4
- 229910021511 zinc hydroxide Inorganic materials 0.000 claims description 4
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical group CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 3
- 244000090896 Nigella sativa Species 0.000 claims description 3
- 235000016698 Nigella sativa Nutrition 0.000 claims description 3
- 125000002138 bisabolol group Chemical group 0.000 claims description 3
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims description 3
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 claims description 3
- 239000001711 nigella sativa Substances 0.000 claims description 3
- 230000002829 reductive effect Effects 0.000 claims description 3
- JNAYPSWVMNJOPQ-UHFFFAOYSA-N 2,3-bis(16-methylheptadecanoyloxy)propyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C JNAYPSWVMNJOPQ-UHFFFAOYSA-N 0.000 claims description 2
- 244000146462 Centella asiatica Species 0.000 claims description 2
- 235000004032 Centella asiatica Nutrition 0.000 claims description 2
- 241000050051 Chelone glabra Species 0.000 claims description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 2
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 2
- 235000016357 Mirtillo rosso Nutrition 0.000 claims description 2
- 240000007164 Salvia officinalis Species 0.000 claims description 2
- 244000223014 Syzygium aromaticum Species 0.000 claims description 2
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims description 2
- 235000017606 Vaccinium vitis idaea Nutrition 0.000 claims description 2
- 244000077923 Vaccinium vitis idaea Species 0.000 claims description 2
- 244000248021 Vitex negundo Species 0.000 claims description 2
- 235000010363 Vitex negundo Nutrition 0.000 claims description 2
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 2
- 235000011477 liquorice Nutrition 0.000 claims description 2
- 235000005412 red sage Nutrition 0.000 claims description 2
- 244000044822 Simmondsia californica Species 0.000 claims 5
- 244000061520 Angelica archangelica Species 0.000 claims 1
- 235000001287 Guettarda speciosa Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 29
- 230000037307 sensitive skin Effects 0.000 abstract description 3
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 abstract 1
- 239000001642 eugenia caryophyllata l. bud extract Substances 0.000 abstract 1
- 229940042585 tocopherol acetate Drugs 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 23
- 239000000047 product Substances 0.000 description 14
- 235000006708 antioxidants Nutrition 0.000 description 12
- 241000221095 Simmondsia Species 0.000 description 11
- 239000002537 cosmetic Substances 0.000 description 8
- 238000012360 testing method Methods 0.000 description 7
- 239000000203 mixture Substances 0.000 description 6
- 208000020154 Acnes Diseases 0.000 description 5
- 230000003110 anti-inflammatory effect Effects 0.000 description 5
- 241001621841 Alopecurus myosuroides Species 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 206010040880 Skin irritation Diseases 0.000 description 3
- 229930003427 Vitamin E Natural products 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 3
- 239000004519 grease Substances 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000004006 olive oil Substances 0.000 description 3
- 235000008390 olive oil Nutrition 0.000 description 3
- 238000011056 performance test Methods 0.000 description 3
- 230000035699 permeability Effects 0.000 description 3
- 230000036556 skin irritation Effects 0.000 description 3
- 231100000475 skin irritation Toxicity 0.000 description 3
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 3
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 3
- 239000011709 vitamin E Substances 0.000 description 3
- 229940046009 vitamin E Drugs 0.000 description 3
- 235000019165 vitamin E Nutrition 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 241000220317 Rosa Species 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 238000009776 industrial production Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 230000008092 positive effect Effects 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 210000002374 sebum Anatomy 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 description 1
- 241000213006 Angelica dahurica Species 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000029462 Immunodeficiency disease Diseases 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 206010030261 Oil acne Diseases 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 206010063493 Premature ageing Diseases 0.000 description 1
- 208000032038 Premature aging Diseases 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 102000003425 Tyrosinase Human genes 0.000 description 1
- 108060008724 Tyrosinase Proteins 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000002199 base oil Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000005282 brightening Methods 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 235000004626 essential fatty acids Nutrition 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 210000003746 feather Anatomy 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- XJNUECKWDBNFJV-UHFFFAOYSA-N hexadecyl 2-ethylhexanoate Chemical group CCCCCCCCCCCCCCCCOC(=O)C(CC)CCCC XJNUECKWDBNFJV-UHFFFAOYSA-N 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000007813 immunodeficiency Effects 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 239000010687 lubricating oil Substances 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- 231100001223 noncarcinogenic Toxicity 0.000 description 1
- 239000000346 nonvolatile oil Substances 0.000 description 1
- 230000004792 oxidative damage Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 229940068065 phytosterols Drugs 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000000770 proinflammatory effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 238000005067 remediation Methods 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 230000037393 skin firmness Effects 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/14—Preparations for removing make-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
Abstract
The application relates to the technical field of cosmetics-cleansing cream, in particular to acne-removing skin-care cleansing cream based on oiled acne muscles and a preparation method thereof. An anti-acne skin care cleansing cream based on oiled acne muscles is mainly prepared from the following raw materials, by weight, 3-4 parts of a skin conditioning agent, 75-80 parts of an emollient, 12-14 parts of an emulsifying agent, 5-6 parts of a thickener-synthetic wax, and 0.15-0.25 part of an antioxidant-tocopherol acetate; the skin conditioner comprises argan kernel oil, stearyl glycyrrhetinate, butanediol, radix salviae miltiorrhizae extract, clove bud extract, radix scutellariae extract, radix angelicae sinensis extract, radix glycyrrhizae extract, centella asiatica extract, bisabolol and centella asiatica extract. The skin care cream is suitable for sensitive skin and oiled acne skin, is mild in makeup removal, can play a role in relieving and repairing skin, and has a good mild makeup removal effect and an acne removal skin care effect.
Description
Technical Field
The application relates to the technical field of cosmetics-cleansing cream, in particular to acne-removing skin-care cleansing cream based on oiled acne muscles and a preparation method thereof.
Background
With the development of social economy and the improvement of the living standard of people, people pay more attention to the appearance of people, and therefore, the cosmetic modification of the appearance by adopting cosmetics is very common. The market of make-up is increased year by year, and the sun-proof products are skin-care explosive products, but the prior make-up and sun-proof products need make-up removal treatment, but the commercial make-up removal products have relatively poor cleaning effects on make-up and sun-proof products and the like which also contain raw materials such as grease, toner, sun-proof agent, film forming agent and the like, or have better make-up removal effects, but have larger irritation, have loss to skin and do not meet the requirements of consumers.
In order to overcome the defects in the related art, the applicant provides an acne-removing skin-care cleansing cream based on the oiled acne muscles and a preparation method thereof.
Disclosure of Invention
In order to solve the technical problems, the application provides a preparation method of acne-removing skin-care makeup-removing cream based on the oiled acne muscles.
In a first aspect, the application provides an acne removing skin care cleansing cream based on oiled acne muscles, which is realized by the following technical scheme:
an anti-acne skin care cleansing cream based on oiled acne muscles is mainly prepared from the following raw materials, by weight, 3-4 parts of a skin conditioning agent, 75-80 parts of an emollient, 12-14 parts of an emulsifying agent, 5-6 parts of a thickening agent and 0.15-0.25 part of an antioxidant; the antioxidant is tocopheryl acetate; the skin conditioning agents comprise a first skin conditioning agent, a second skin conditioning agent, a third skin conditioning agent, a fourth skin conditioning agent and a fifth skin conditioning agent, wherein the first skin conditioning agent is argania spinosa kernel oil; the second skin conditioner is stearyl glycyrrhetinate; the third skin conditioner is composed of butanediol, radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix Scutellariae extract, radix Angelicae sinensis extract, radix Glycyrrhizae extract, and herba Centellae extract; the fourth skin conditioner is bisabolol; the fifth skin conditioner is centella asiatica extract; the first emollient comprises cetyl ethyl caproate; the second emollient is composed of grape seed oil, sunflower seed oil and wild soybean oil; the third emollient is composed of butter fruit, oil palm oil, jojoba seed oil, tocopherol, and cowberry fruit extract; the fourth emollient is cultivated nigella sativa seed oil; the fifth emollient is squalane; the sixth emollient is jojoba seed oil.
The skin care cream is suitable for sensitive skin and oiled acne skin, is mild in makeup removal, can play a role in relieving and repairing skin, and has a good mild makeup removal effect and an acne removal skin care effect.
Preferably, the mass ratio of the first skin conditioning agent to the second skin conditioning agent to the third skin conditioning agent to the fourth skin conditioning agent to the fifth skin conditioning agent is (18-24): 4-6): 1:1.
The first skin conditioner, argania spinosa kernel oil, contains a large amount of fatty acids, sterols, vitamin E and phenolic compounds. The argania spinosa kernel oil contains a large amount of essential fatty acids, unsaturated fatty acids and linoleic acid, which cannot be synthesized in human bodies and must be obtained from fat. The hydration degree of the fatty acid for maintaining the health of a human body is researched, and the application of linoleic acid on the skin has obvious effects of resisting inflammation, reducing acne and keeping moisture; whereas the lack of essential unsaturated fatty acids can lead to premature aging and wrinkling of the skin; the argania spinosa kernel oil has been scientifically demonstrated to contain 2 times as much vitamin E as olive oil and also contains rare phytosterols which can help soften skin, stimulate pores to expel toxin and restore natural lipid barrier. Polyphenols are well known antioxidants, which not only delay skin aging, but also prolong the duration of action of other antioxidants in the human body, such as vitamin E, vitamin C.
The second skin conditioner, 100% vegetable origin of stearyl glycyrrhetinate, olive oil derivatives, anti-redness and anti-inflammatory, sebum remediation. Stearyl alcohol glycyrrhetinate has antibacterial, antiinflammatory, antioxidant, and antiaging effects. It can also reduce the toxic and side effects of cosmetics or other factors on skin in the cosmetic industry.
The third skin conditioner has good effects of controlling oil, removing acnes and inhibiting acnes.
The fourth skin conditioning agent imparts good anti-inflammatory, anti-irritant, antibacterial and non-carcinogenic properties to the present application.
The centella asiatica extract as the fifth skin conditioner has strong skin pharmacological activity and is used for anti-aging and skin repairing cosmetic products. Centella asiatica extract is an excellent phytoremediation ingredient. Has very good antibacterial effect, and can be used for treating acne; can reduce the generation of pro-inflammatory mediators, improve and repair the self barrier function of skin, thereby preventing and correcting skin immune dysfunction, achieving the anti-inflammatory effect, and being used in cosmetics for repairing after sun, resisting allergy and relieving. The centella asiatica extract also has the promotion effect of fibroblast and collagen synthesis, and can maintain skin elasticity and firmness, and smooth fine wrinkles on face. Centella asiatica extract has a broad market prospect in various personal care fields.
Preferably, the mass ratio of the butanediol, the root extract of red sage, the bud extract of clove, the root extract of baical skullcap root, the root extract of Chinese angelica, the root extract of liquorice and the centella asiatica in the third skin conditioner is 84:8:3:2:1.4:0.8:0.8.
Through the scheme, the third skin conditioner endows the application with good effects of controlling oil, removing acnes and inhibiting acnes, and meanwhile, the production cost is reduced on the premise of ensuring the effect.
Preferably, the mass ratio of the first emollient to the second emollient to the third emollient to the fourth emollient to the fifth emollient to the sixth emollient is (44-48): (24-28): (4-5): (1-2): (1-2): (0.4-0.8).
The first emollient, cetyl alcohol ethyl hexanoate, commonly known as sea bird feather oil, is a soft emollient with particularly excellent waterproof performance, has good air permeability and spreadability, is not sticky and greasy, has thickening effect, and can moisten and soften skin.
The second emollient, grape seed oil, contains various antioxidant substances, protects cells from oxidative damage, delays aging process, is high in freshness, is not greasy, and has extremely high permeability. The grape seed oil is rich in polyunsaturated fatty acid, has an antioxidant function, and is helpful for repairing and brightening skin; the sunflower seed oil is an important base oil raw material of cosmetics, has the effects of lubricating skin, activating a peroxidase activated receptor, promoting skin wound healing and resisting inflammation, has a certain inhibition effect on tyrosinase, and has the whitening effect.
The third emollient is soft sweet, has strong antioxidant effect, has fine cranberry particles, and can be mixed with other organic certification ingredients to form soft and comfortable skin feel and good spreadability.
And fourthly, cultivating the black grass seed oil by using the emollients, wherein the cultivated black grass seed oil contains fixed oil, and the main component of the seed oil is saponin, so that the seed oil can lubricate, clean skin and condition the secretion of grease on the skin. The black grass is extremely rich in unsaturated fatty acid content, so that the black grass can be qualified as a name of 'skin food', can nourish, pacify, soften and dry skin, improve eczema, psoriasis, dermatitis and acne, is excellent in overnight repair and care oil, can greatly improve the overall condition of skin after regular use, can increase skin fineness and softness, and has the effect of reducing wrinkles.
The fifth emollient squalane is extracted from olive oil, is a natural component in skin, has good effects of resisting oxidization and stimulating immunity, can be quickly dissolved with moisture and grease in skin to form a natural skin protection barrier, has excellent stability, can not generate oxidization with air, ultraviolet rays and the like, can effectively protect the skin from being affected by external substances, has excellent penetrability and high-efficiency oxygen carrying property, can regulate the water-oil balance of the skin, avoids the roughness and darkness of the skin, and enables the skin to recover the original tender touch. Is especially suitable for use in cold season, is lubricating oil for skin, and can supplement natural sebum for skin.
Besides the vitamin a, the vitamin b and the vitamin e which are very rich in the sixth emollient, the jojoba seed oil also contains minerals such as calcium, magnesium and the like, has better permeability, can improve the stability and the efficacy of the application, and helps the skin to solve the skin blemish problems such as dryness, lack of water, roughness, darkness and the like.
Preferably, the grape seed oil, the sunflower seed oil and the wild soybean oil in the second emollient are formed by the mass ratio of 40:30:30; the butter fruit oil, oil palm oil, jojoba seed oil, tocopherol and cranberry fruit extract in the third emollient are prepared according to a mass ratio of 43.75:45:5.5:0.25:5.5.
Preferably, the emulsifying agent comprises a first emulsifying agent, a second emulsifying agent and a third emulsifying agent, wherein the first emulsifying agent is PEG-20 glycerol triisostearate, and the second emulsifying agent is polyglycerol-10 dioleate; the third emulsifier is composed of jojoba esters, sunflower seed wax, acacia negra flower wax, polyglycerol-3 and tocopherol.
Preferably, the mass ratio of the first emulsifier to the second emulsifier to the third emulsifier is (8-12) 1:1.
Preferably, the mass ratio of jojoba esters, sunflower seed wax, acacia negra wax, polyglycerol-3 and tocopherol in the third emulsifier is 62:32:2.98:3:0.02.
S1, mixing 100g of 300-500-mesh coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500-mL three-neck flask, stirring uniformly by using ultrasonic waves, heating to 140-155 ℃ by an oil bath, controlling the heating speed to 4-6 ℃/min, maintaining the temperature at 140-155 ℃ for 20-30min, cooling to room temperature, centrifuging, separating, cleaning, and naturally drying to obtain the coffee grounds with zinc particles on the surface; s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to the mass ratio of 1:1:1:1:1 to form composite amino acid, 20-40g of the composite amino acid is weighed and dissolved in 100-1000mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained; s3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with the sodium hydroxide to form zinc hydroxide, adding the zinc particles on the surfaces of the coffee grounds treated by the sodium hydroxide into the compound amino acid solution obtained in the S2, reacting the compound amino acid with zinc ions in a molar ratio of = 2:1, heating the water bath to 80-85 ℃ to react, simultaneously, continuously dropwise adding 0.1-0.3moL of sodium hydroxide solution to react for 6-8h, filtering to remove unreacted insoluble substances, adding an acetone solution to treat, draining, and drying at 60-65 ℃ to obtain the surface modified coffee grounds.
The effect of the cleansing experience of the cleansing cream can be improved by introducing the coffee grounds in the cleansing cream, the cleansing experience of consumers is improved, and therefore the cleansing cream is easier to accept by mass consumers and is convenient to be brought to the market. According to the preparation method, the active anti-inflammatory and antibacterial carrier formed by introducing the compound amino acid and zinc ions on the surface of the coffee grounds can play roles in relieving, diminishing inflammation, resisting bacteria and repairing skin, and the market competitiveness of the product is improved.
In a second aspect, the preparation method of the acne-removing skin-care makeup-removing cream based on the oiled acne muscles is realized through the following technical scheme:
a preparation method of acne-removing skin-care cleansing cream based on oiled acne muscles comprises the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a first thickener, a first skin conditioner, a second emulsifier, a second thickener and a sixth emollient into a pot, starting stirring and heating at 500-600rpm, heating to 85+/-5 ℃, adding a second skin conditioner, a fourth skin conditioner and an antioxidant serving as raw material components after materials are completely melted, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioning agent and the fifth skin conditioning agent into a clean stainless steel barrel, heating to 80+/-5 ℃, stirring until the components are uniformly melted, slowly adding into a pot, and stirring for 10-20min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and when the material body is taken out of the pot, filtering is carried out, and a filter screen is 80-100 meshes.
The preparation method is relatively simple, low in operation difficulty and convenient to realize industrial production and manufacture.
In summary, the present application has the following advantages:
1. the skin care cream is suitable for sensitive skin and oiled acne skin, is mild in makeup removal, can play a role in relieving and repairing skin, and has a good mild makeup removal effect and an acne removal skin care effect.
2. The preparation method is relatively simple, low in operation difficulty and convenient to realize industrial production and manufacture.
Detailed Description
The present application is described in further detail below in conjunction with comparative examples and examples.
Preparation example
Preparation example 1
The preparation method of the surface modified coffee grounds comprises the following steps:
s1, mixing 100g of 500-mesh coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500-mL three-neck flask, stirring by using ultrasonic until the mixture is uniformly dispersed, heating to 145 ℃ by using an oil bath, controlling the heating speed to 5 ℃/min, maintaining the temperature at 145 ℃ for 20-30min, cooling to room temperature, centrifuging, separating, cleaning, and naturally drying to obtain the coffee grounds with zinc particles on the surface;
s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to a mass ratio of 1:1:1:1:1 to form composite amino acid, 40g of the composite amino acid is weighed and dissolved in 500mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained;
and S3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with sodium hydroxide to form zinc hydroxide, adding the coffee grounds with zinc particles on the surfaces treated by sodium hydroxide into the compound amino acid solution obtained in the S2, reacting the compound amino acid with zinc ions in a molar ratio of = 2:1, heating the water bath to 80 ℃ for reaction, simultaneously, continuously dropwise adding 0.15moL of sodium hydroxide solution for reaction for 8.0h, filtering to remove unreacted insoluble substances, adding an acetone solution for treatment, draining, and drying at 60 ℃ to obtain the surface modified coffee grounds.
Preparation example 2
Preparation 2 differs from preparation 1 in that: and S1, performing activation treatment on the 500-mesh coffee grounds at 275 ℃ for 2 hours to obtain the 500-mesh activated coffee grounds.
Preparation example 3
Preparation 3 differs from preparation 1 in that: s2, mixing aspartic acid, serine and lysine according to the mass ratio of 1:1:1 to form composite amino acid, weighing 20-40g of the composite amino acid, dissolving in 100-1000mL of pure water, stirring, and filtering to remove undissolved components to obtain the composite amino acid solution.
Examples
An acne removing skin care cleansing cream based on oiled acne muscles is mainly prepared from the following raw materials in parts by weight: 3-4 parts of skin conditioning agent, 75-80 parts of emollient, 12-14 parts of emulsifier, 5-6 parts of thickener and 0.15-0.25 part of antioxidant.
The antioxidant is tocopheryl acetate. The thickener is synthetic wax.
The skin conditioning agents comprise a first skin conditioning agent, a second skin conditioning agent, a third skin conditioning agent, a fourth skin conditioning agent and a fifth skin conditioning agent, and the mass ratio of the first skin conditioning agent to the second skin conditioning agent to the third skin conditioning agent to the fourth skin conditioning agent to the fifth skin conditioning agent is (18-24): (4-6): (4-6): 1:1.
the first skin conditioner is argania spinosa kernel oil.
The second skin conditioner is stearyl glycyrrhetinate.
The third skin conditioner comprises butanediol, saviae Miltiorrhizae radix extract, flos Caryophylli bud extract, scutellariae radix extract, radix Angelicae sinensis extract, glycyrrhrizae radix extract, and herba Centellae extract.
The mass ratio of butanediol, radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix Scutellariae extract, radix Angelicae sinensis extract, radix Glycyrrhizae extract, and herba Centellae extract in the third skin conditioner is 84:8:3:2:1.4:0.8:0.8.
The fourth skin conditioner is bisabolol.
The fifth skin conditioner is centella asiatica extract.
The emollients comprise a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient and a sixth emollient, and the mass ratio of the first emollient, the second emollient, the third emollient, the fourth emollient, the fifth emollient and the sixth emollient is (44-48): (24-28): (4-5): (1-2): (1-2): (0.4-0.8).
The first emollient is cetyl ethyl hexanoate.
The second emollient is composed of grape seed oil, sunflower seed oil and wild soybean oil, wherein the mass ratio of grape seed oil, sunflower seed oil and wild soybean oil is 40:30:30.
The third emollient is composed of butter fruit oil, oil palm oil, jojoba seed oil, tocopherol, and cranberry fruit extract, wherein the mass ratio of butter fruit oil, oil palm oil, jojoba seed oil, tocopherol, cranberry fruit extract is 43.75:45:5.5:0.25:5.5.
The fourth emollient is cultivated nigella sativa seed oil.
The fifth emollient is squalane.
The sixth emollient is jojoba seed oil.
The emulsifying agent comprises a first emulsifying agent, a second emulsifying agent and a third emulsifying agent, wherein the mass ratio of the first emulsifying agent to the second emulsifying agent to the third emulsifying agent is (8-12) 1:1. The first emulsifier is PEG-20 triisostearate, the second emulsifier is polyglycerol-10 dioleate, and the third emulsifier is composed of jojoba esters, sunflower seed wax, acacia wax, polyglycerol-3 and tocopherol. The mass ratio of jojoba esters, sunflower seed wax, vitex negundo flower wax, polyglycerol-3 and tocopherol is 62:32:2.98:3:0.02.
In addition, 3-6 parts of 300-500 mesh surface modified coffee grounds are included.
The preparation method of the surface modified coffee grounds comprises the following steps:
s1, mixing 100g of 300-500 meshes of coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500mL three-neck flask, stirring by using ultrasonic until the mixture is uniformly dispersed, heating to 140-155 ℃ by using an oil bath, controlling the heating speed to 4-6 ℃/min, maintaining the temperature at 140-155 ℃ for 20-30min, cooling to room temperature, centrifuging, separating, cleaning, naturally drying, and obtaining the coffee grounds with zinc particles on the surface;
s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to the mass ratio of 1:1:1:1:1 to form composite amino acid, 20-40g of the composite amino acid is weighed and dissolved in 100-1000mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained;
s3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with the sodium hydroxide to form zinc hydroxide, and then adding the coffee grounds with the zinc particles on the surfaces treated by the sodium hydroxide into the compound amino acid solution obtained in the S2, wherein the compound amino acid comprises the following steps of: the molar ratio of zinc ions=2:1 is reacted, the water bath is heated to 80-85 ℃ for reaction, 0.1-0.3moL of sodium hydroxide solution is continuously added dropwise for reaction for 6-8 hours, unreacted insoluble substances are removed by filtration, then acetone solution is added for treatment, and the surface modified coffee grounds are obtained after draining and drying at 60-65 ℃.
See in particular the surface-modified coffee grounds obtained in preparation examples 1-3.
A preparation method of acne-removing skin-care cleansing cream based on oiled acne muscles comprises the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a thickener, a first skin conditioner, a second emulsifier and a sixth emollient into a pot, starting stirring and heating at 500-600rpm, heating to 85+/-5 ℃, adding a second skin conditioner, a fourth skin conditioner and an antioxidant serving as raw material components after materials are completely melted, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioning agent and the fifth skin conditioning agent into a clean stainless steel barrel, heating to 80+/-5 ℃, stirring until the components are uniformly melted, slowly adding into a pot, and stirring for 10-20min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and when the material body is taken out of the pot, filtering is carried out, and a filter screen is 80-100 meshes.
Examples 1 to 4
The application discloses an acne removing skin care cleansing cream based on oiled acne muscles, and the formula is shown in table 1:
table 1 shows the formulation of the acne-removing skin-care cleansing cream of examples 1 to 4
A preparation method of acne-removing skin-care cleansing cream based on oiled acne muscles comprises the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a thickener, a first skin conditioner, a second emulsifier and a sixth emollient into a pot, starting stirring and heating, heating at a stirring speed of 500rpm, heating to 85 ℃, adding a raw material component of the second skin conditioner, the fourth skin conditioner and an antioxidant after the materials are completely dissolved, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioner and the fifth skin conditioner in a clean stainless steel barrel, heating to 80 ℃, stirring until the components are melted uniformly, slowly putting into a pot, and stirring for 15min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and the material body is filtered when being taken out of the pot, and a filter screen is 80-100 meshes, so that a finished product is obtained.
Examples 5 to 9
The differences between examples 5-9 and example 1 are as follows in Table 2:
table 2 shows the formulation of the acne-removing skin-care cleansing cream of examples 5 to 9
/>
Examples 10 to 12
Examples 10-12 differ from example 1 as shown in Table 3 below:
table 3 shows the formulation of the acne-removing skin-care cleansing cream of examples 10 to 12
/>
Comparative example
Comparative examples 1-4 differ from example 1 in table 4 below:
table 4 is a formulation table of the acne-removing skin-care cleansing cream of comparative examples 1 to 4
/>
Comparative example 5 is a Dior rose extract cleansing cream.
Performance test
Detection method/test method
The test evaluation method comprises the following steps:
test volunteers 10, requirement: the ages are between 16 years and 65 years; patients with no serious systemic disease, no immunodeficiency or autoimmune disease; patients with no active allergic disease; the prior skin care cosmetics have no serious allergic history; hormonal drugs and immunosuppressants have not been used for about 1 month; those who did not participate in other clinical trials; the test object is used according to the specification and the data is complete; all volunteers should fill in informed consent prior to testing.
Test object: acne-removing skin-care cleansing cream in examples 1 to 12 and comparative examples 1 to 5.
The testing method comprises the following steps: the acne-removing skin-care cleansing cream of examples 1 to 12 and comparative examples 1 to 5 were put into plastic barrels of the same size and were used by the testers after the products were in the order of the sequential labels A1, A2, A3, A4, B1, B2, B3, B4, B5, C1, C2, C3, D1, D2, D3, D4, E. The test time is 12 days, and the cleansing performance, the mildness (sensitivity) performance, the acne removal performance and the skin care performance of the product are evaluated by using the product once a day in the morning and evening.
The evaluation effect was classified into 4 grades, grade 1 being poor, grade 2 being general, grade 3 being better, grade 4 being good.
Data analysis
Table 5 is a table of the makeup removing performance test parameters of the acne-removing skin care makeup removing cream of examples 1 to 12 and comparative examples 1 to 4
Table 6 is a table of comprehensive performance test parameters of the anti-acne skin care cleansing cream of examples 1 to 12 and comparative examples 1 to 4
Comprehensive makeup removing performance | Mild Properties | Acne-removing property | Skin care properties | |
Example 1 | 3.804 | 3.72 | 3.58 | 3.82 |
Example 2 | 3.764 | 3.58 | 3.55 | 3.76 |
Example 3 | 3.772 | 3.63 | 3.46 | 3.72 |
Example 4 | 3.618 | 3.55 | 3.42 | 3.68 |
Example 5 | 3.712 | 3.68 | 3.54 | 3.61 |
Example 6 | 3.716 | 3.70 | 3.45 | 3.54 |
Example 7 | 3.766 | 3.73 | 3.42 | 3.49 |
Example 8 | 3.774 | 3.69 | 3.42 | 3.45 |
Example 9 | 3.804 | 3.70 | 3.45 | 3.51 |
Example 10 | 3.802 | 3.65 | 3.60 | 3.85 |
Example 11 | 3.826 | 3.68 | 3.63 | 3.87 |
Example 12 | 3.744 | 3.61 | 3.55 | 3.84 |
Comparative example 1 | 3.410 | 3.65 | 3.55 | 3.78 |
Comparative example 2 | 2.896 | 3.58 | 3.57 | 3.75 |
Comparative example 3 | 3.574 | 3.55 | 2.85 | 2.91 |
Comparative example 4 | 3.592 | 3.61 | 2.92 | 2.83 |
Comparative example 5 | 3.782 | 3.70 | 3.42 | 3.75 |
As can be seen from a combination of examples 1-12 and comparative examples 1-5 and from a comparison of tables 5-6, example 1 and comparative examples 1-2 demonstrate that the three types of emulsifiers used in the present application, combined, provide improved overall cleansing and mildness, and reduced skin irritation.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and the combination of tables 5-6, the skin conditioning agents obtained by compounding the five skin conditioning agents used in the application can improve the acne removing performance and the skin care performance of the application, have positive effects on the makeup removing performance and reduce the irritation to the skin as compared with comparative example 3.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and the combination of tables 5-6, the use of the six emollients in the present application results in an emollient that improves the anti-acne and skin care properties of the present application, has a positive effect on the anti-makeup properties, and reduces skin irritation.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and the combination of tables 5-6, the acne-removing skin-care cleansing cream prepared in the present application is comparable to the hot-spot dio rose extract cleansing cream in terms of performance, and the present application has a market competitive advantage.
As can be seen by combining examples 1-12 and comparative examples 1-5 and combining tables 5-6, the anti-acne skin care cleansing cream prepared by the example 1 and the example 2-4 has better effects of relieving and repairing skin and removing acnes, and is suitable for sensitive muscles and oilpox skin.
As can be seen by combining examples 1-12 and comparative examples 1-5 and combining tables 5-6, the comparison between examples 1 and 5-9 shows that the skin care cream prepared by the mass ratio of the first skin conditioner to the second skin conditioner to the third skin conditioner to the fourth skin conditioner to the fifth skin conditioner is (18-24): 4-6): 4-6:1:1 has better skin care effect and acne care effect, and is suitable for sensitive muscles and oilpox skin.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and tables 5-6, the surface modified coffee grounds added in the present application can improve the acne removing effect and skin care performance of the present application, and have less skin irritation and mild cleansing effect.
In conclusion, the acne-removing and skin-care cream is suitable for skin quality of sensitive muscles and oilacnes, and can be used for mildly removing makeup, and simultaneously has the effect of relieving and repairing the skin, namely, has a good mildly removing makeup effect and has the acne-removing and skin-care effects.
The present embodiment is merely illustrative of the present application and is not intended to be limiting, and those skilled in the art, after having read the present specification, may make modifications to the present embodiment without creative contribution as required, but is protected by patent laws within the scope of the claims of the present application.
Claims (10)
1. An anti-acne skin care cleansing cream based on oiled acne muscles is characterized by being prepared from the following raw materials, by weight, 3-4 parts of a skin conditioning agent, 75-80 parts of an emollient, 12-14 parts of an emulsifying agent, 5-6 parts of a thickening agent and 0.15-0.25 part of an antioxidant; the antioxidant is tocopheryl acetate; the thickener is synthetic wax.
2. The acne-removing skin care cleansing cream based on the oiled poxus muscles, which is characterized in that the skin conditioning agents comprise a first skin conditioning agent, a second skin conditioning agent, a third skin conditioning agent, a fourth skin conditioning agent and a fifth skin conditioning agent, wherein the first skin conditioning agent is argania spinosa kernel oil; the second skin conditioner is stearyl glycyrrhetinate; the third skin conditioner is composed of butanediol, radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix Scutellariae extract, radix Angelicae sinensis extract, radix Glycyrrhizae extract, and herba Centellae extract; the fourth skin conditioner is bisabolol; the fifth skin conditioner is centella asiatica extract; the mass ratio of the first skin conditioning agent to the second skin conditioning agent to the third skin conditioning agent to the fourth skin conditioning agent to the fifth skin conditioning agent is (18-24): 4-6): 1:1.
3. The acne-removing skin-care cleansing cream based on the oiled poxes according to claim 1 or 2, wherein the mass ratio of the butanediol to the root extract of red sage to the bud extract of clove to the root extract of baical skullcap, the root extract of angelica to the root extract of liquorice to the centella asiatica is 84:8:3:2:1.4:0.8:0.8.
4. The acne-removing skin care cleansing cream based on the oiliness skin according to claim 1, wherein the emollient comprises a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient and a sixth emollient, and the first emollient is cetyl ethyl caproate; the second emollient is composed of grape seed oil, sunflower seed oil and wild soybean oil; the third emollient is composed of butter fruit, oil palm oil, jojoba seed oil, tocopherol, and cowberry fruit extract; the fourth emollient is cultivated nigella sativa seed oil; the fifth emollient is squalane; the sixth emollient is jojoba seed oil; the mass ratio of the first emollient to the second emollient to the third emollient to the fourth emollient to the fifth emollient to the sixth emollient is (44-48): (24-28): (4-5): (1-2): (1-2): (0.4-0.8).
5. The acne-removing skin-care cleansing cream based on the oiled acne muscles, which is characterized in that grape seed oil, sunflower seed oil and wild soybean oil in the second emollient are prepared according to a mass ratio of 40:30:30; the butter fruit oil, oil palm oil, jojoba seed oil, tocopherol and cranberry fruit extract in the third emollient are prepared according to a mass ratio of 43.75:45:5.5:0.25:5.5.
6. The acne-removing skin care cleansing cream based on the oiled poxy muscles according to claim 4, wherein the emulsifying agent comprises a first emulsifying agent, a second emulsifying agent and a third emulsifying agent, wherein the first emulsifying agent is PEG-20 glycerol triisostearate, and the second emulsifying agent is polyglycerol-10 dioleate; the third emulsifier is composed of jojoba esters, sunflower seed wax, acacia negra flower wax, polyglycerol-3 and tocopherol.
7. The acne-removing skin care cleansing cream based on the oiled poxes according to claim 6, wherein the mass ratio of the first emulsifier to the second emulsifier to the third emulsifier is (8-12): 1:1.
8. The acne-removing skin-care cleansing cream based on the oiled poxes according to claim 6, wherein the mass ratio of jojoba esters, sunflower seed wax, vitex negundo flower wax, polyglycerol-3 and tocopherol in the third emulsifier is 62:32:2.98:3:0.02.
9. The acne-removing skin care cleansing cream based on the oiled poxes according to claim 6 is characterized by further comprising 3-6 parts of 300-500 mesh surface modified coffee grounds, wherein the preparation method of the surface modified coffee grounds comprises the following steps of S1, mixing 100g of 300-500 mesh coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500mL three-neck flask, stirring uniformly by using ultrasonic waves, heating to 140-155 ℃ by using an oil bath, controlling the heating speed to 4-6 ℃/min, maintaining the temperature at 140-155 ℃ for 20-30min to be reduced to room temperature, centrifuging, cleaning, and naturally drying to obtain the coffee grounds with zinc particles on the surface; s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to the mass ratio of 1:1:1:1:1 to form composite amino acid, 20-40g of the composite amino acid is weighed and dissolved in 100-1000mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained; s3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with the sodium hydroxide to form zinc hydroxide, adding the zinc particles on the surfaces of the coffee grounds treated by the sodium hydroxide into the compound amino acid solution obtained in the S2, reacting the compound amino acid with zinc ions in a molar ratio of = 2:1, heating the water bath to 80-85 ℃ to react, simultaneously, continuously dropwise adding 0.1-0.3moL of sodium hydroxide solution to react for 6-8h, filtering to remove unreacted insoluble substances, adding an acetone solution to treat, draining, and drying at 60-65 ℃ to obtain the surface modified coffee grounds.
10. A method for preparing the acne-removing skin-care makeup-removing cream based on the oiled poxes according to claim 9, which is characterized by comprising the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a thickener, a first skin conditioner, a second emulsifier and a sixth emollient into a pot, starting stirring and heating at 500-600rpm, heating to 85+/-5 ℃, adding a second skin conditioner, a fourth skin conditioner and an antioxidant serving as raw material components after materials are completely melted, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioning agent and the fifth skin conditioning agent into a clean stainless steel barrel, heating to 80+/-5 ℃, stirring until the components are uniformly melted, slowly adding into a pot, and stirring for 10-20min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and when the material body is taken out of the pot, filtering is carried out, and a filter screen is 80-100 meshes.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310598751.7A CN116549323A (en) | 2023-05-22 | 2023-05-22 | Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310598751.7A CN116549323A (en) | 2023-05-22 | 2023-05-22 | Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN116549323A true CN116549323A (en) | 2023-08-08 |
Family
ID=87501713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310598751.7A Pending CN116549323A (en) | 2023-05-22 | 2023-05-22 | Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN116549323A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117427018A (en) * | 2023-12-22 | 2024-01-23 | 广州海龟爸爸生物科技有限公司 | Centella asiatica extract and transparent zinc oxide sun-screening composition and application thereof |
-
2023
- 2023-05-22 CN CN202310598751.7A patent/CN116549323A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117427018A (en) * | 2023-12-22 | 2024-01-23 | 广州海龟爸爸生物科技有限公司 | Centella asiatica extract and transparent zinc oxide sun-screening composition and application thereof |
CN117427018B (en) * | 2023-12-22 | 2024-03-12 | 广州海龟爸爸生物科技有限公司 | Centella asiatica extract and transparent zinc oxide sun-screening composition and application thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106880551B (en) | Body lotion for tightening, moistening and smoothing skin and preparation method thereof | |
CN103340817B (en) | Radix puerariae whitening facial mask | |
CN102113987B (en) | Cosmetic containing natural plant extractives and preparation method thereof | |
CN107913218A (en) | A kind of compound elite preparation with senile-resistant efficacy and its preparation method and application | |
CN105505635B (en) | A kind of skin cleansing composition and preparation method thereof containing lotus active constituent | |
CN109010115A (en) | A kind of Shu Min creams with anti-inflammatory efficacy | |
CN109966183A (en) | A kind of moisturizing remediation composition and its preparation method and application | |
CN107397700A (en) | Camellia soothing oil nourishes cosmetics and preparation method thereof | |
CN103565727A (en) | Lycium ruthenicum mill moisturizing and whitening cream and preparation method thereof | |
CN105997827A (en) | Compound camellia oil moisturizer and preparation method thereof | |
CN110787088A (en) | Basic composition for lip wrinkle fading and preparation method and application thereof | |
CN116549323A (en) | Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof | |
US20150182443A1 (en) | Traditional chinese medicine extract composition with whitening skin-care function adn its preparation method | |
KR101308669B1 (en) | Cosmetic composition with the nebaneba complex of hibiscus esculentus, laminaria japonica, dioscorea opposita, corchorus olitorius and nelumbo nucifera, polyglutamic acid | |
KR20140048700A (en) | Natural soap by using of ripen and decocted oriental medicine with the function of making age spots and wrinkles better and manufacturing method thereof | |
CN110559230A (en) | Anti-aging and anti-wrinkle essence lotion and preparation method thereof | |
CN105267717A (en) | Natural herbaceous-plant soup possessing multiple cosmetic efficacies and application thereof | |
KR20140145278A (en) | Cosmetic composition containing Cimicifuga heracleifolia extract, Cornus officinalis extract and Geranium nepalense extract for skin convergence and elasticity effect | |
CN106667813A (en) | Natural plant sunscreen nano emulsion | |
CN112370378A (en) | Cosmetic containing guayule troponin stock solution and preparation method thereof | |
CN106727266A (en) | A kind of anti-aging isolation suncream and preparation method thereof | |
CN104013549B (en) | Skin care product containing lethariella sinensis extract | |
JP2006131558A (en) | Collagen formation enhancer | |
CN101766558A (en) | Acne-removing cosmetic composite | |
KR20160003918A (en) | Cosmetic composition for enhancing skin elasticity or improving skin wrinkle containing herb extracts |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |