CN108125240B - 一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用 - Google Patents
一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用 Download PDFInfo
- Publication number
- CN108125240B CN108125240B CN201711471889.1A CN201711471889A CN108125240B CN 108125240 B CN108125240 B CN 108125240B CN 201711471889 A CN201711471889 A CN 201711471889A CN 108125240 B CN108125240 B CN 108125240B
- Authority
- CN
- China
- Prior art keywords
- extract
- blood sugar
- parts
- composition
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000008280 blood Substances 0.000 title claims abstract description 160
- 210000004369 blood Anatomy 0.000 title claims abstract description 160
- 235000000346 sugar Nutrition 0.000 title claims abstract description 80
- 230000001603 reducing effect Effects 0.000 title claims abstract description 67
- 239000000203 mixture Substances 0.000 title claims abstract description 52
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 239000000284 extract Substances 0.000 claims abstract description 96
- 235000003283 Pachira macrocarpa Nutrition 0.000 claims abstract description 86
- 235000014364 Trapa natans Nutrition 0.000 claims abstract description 86
- 235000009165 saligot Nutrition 0.000 claims abstract description 86
- 241000195633 Dunaliella salina Species 0.000 claims abstract description 60
- 235000007516 Chrysanthemum Nutrition 0.000 claims abstract description 44
- 235000013361 beverage Nutrition 0.000 claims abstract description 35
- 240000008042 Zea mays Species 0.000 claims abstract description 32
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 31
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 31
- 235000005822 corn Nutrition 0.000 claims abstract description 31
- 235000013305 food Nutrition 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 78
- 241001083492 Trapa Species 0.000 claims description 73
- 239000000243 solution Substances 0.000 claims description 49
- 241000723353 Chrysanthemum Species 0.000 claims description 43
- 238000000605 extraction Methods 0.000 claims description 34
- 239000007788 liquid Substances 0.000 claims description 33
- 239000000287 crude extract Substances 0.000 claims description 25
- 238000009835 boiling Methods 0.000 claims description 21
- 238000010992 reflux Methods 0.000 claims description 21
- 238000002791 soaking Methods 0.000 claims description 21
- 238000000926 separation method Methods 0.000 claims description 17
- 239000013505 freshwater Substances 0.000 claims description 16
- 238000002156 mixing Methods 0.000 claims description 16
- 239000002244 precipitate Substances 0.000 claims description 15
- 230000001954 sterilising effect Effects 0.000 claims description 13
- 238000009833 condensation Methods 0.000 claims description 11
- 230000005494 condensation Effects 0.000 claims description 11
- 150000002632 lipids Chemical class 0.000 claims description 8
- 241000628997 Flos Species 0.000 claims description 6
- 239000012267 brine Substances 0.000 claims description 3
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 23
- 235000013343 vitamin Nutrition 0.000 abstract description 17
- 239000011782 vitamin Substances 0.000 abstract description 17
- 229940088594 vitamin Drugs 0.000 abstract description 17
- 229930003231 vitamin Natural products 0.000 abstract description 17
- 240000001085 Trapa natans Species 0.000 abstract description 13
- 235000016709 nutrition Nutrition 0.000 abstract description 10
- 235000015097 nutrients Nutrition 0.000 abstract description 9
- 230000035764 nutrition Effects 0.000 abstract description 9
- 201000007100 Pharyngitis Diseases 0.000 abstract description 8
- 239000000126 substance Substances 0.000 abstract description 7
- 235000005911 diet Nutrition 0.000 abstract description 6
- 201000010099 disease Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 230000002708 enhancing effect Effects 0.000 abstract description 6
- 230000006870 function Effects 0.000 abstract description 6
- 238000002560 therapeutic procedure Methods 0.000 abstract description 6
- 230000002265 prevention Effects 0.000 abstract description 5
- 150000001413 amino acids Chemical class 0.000 abstract description 4
- 230000000378 dietary effect Effects 0.000 abstract description 4
- 230000036039 immunity Effects 0.000 abstract description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract description 3
- 230000004060 metabolic process Effects 0.000 abstract description 3
- 239000011707 mineral Substances 0.000 abstract description 3
- 235000010755 mineral Nutrition 0.000 abstract description 3
- 230000001105 regulatory effect Effects 0.000 abstract description 3
- 208000035240 Disease Resistance Diseases 0.000 abstract description 2
- 230000001502 supplementing effect Effects 0.000 abstract description 2
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 239000003925 fat Substances 0.000 description 56
- 235000019197 fats Nutrition 0.000 description 56
- 238000001914 filtration Methods 0.000 description 31
- 239000000706 filtrate Substances 0.000 description 29
- 210000004027 cell Anatomy 0.000 description 21
- 241000195634 Dunaliella Species 0.000 description 12
- 208000024891 symptom Diseases 0.000 description 12
- 241000282414 Homo sapiens Species 0.000 description 10
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
- 238000012545 processing Methods 0.000 description 8
- 238000004659 sterilization and disinfection Methods 0.000 description 8
- 238000003756 stirring Methods 0.000 description 8
- 230000003698 anagen phase Effects 0.000 description 7
- 230000006378 damage Effects 0.000 description 7
- 239000012528 membrane Substances 0.000 description 7
- 238000009924 canning Methods 0.000 description 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 238000001035 drying Methods 0.000 description 6
- 235000013372 meat Nutrition 0.000 description 6
- 150000003722 vitamin derivatives Chemical class 0.000 description 6
- 239000012535 impurity Substances 0.000 description 5
- 239000000049 pigment Substances 0.000 description 5
- 238000001556 precipitation Methods 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 230000035807 sensation Effects 0.000 description 5
- 235000019615 sensations Nutrition 0.000 description 5
- 206010013952 Dysphonia Diseases 0.000 description 4
- 208000031226 Hyperlipidaemia Diseases 0.000 description 4
- 239000003086 colorant Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 235000009200 high fat diet Nutrition 0.000 description 4
- 201000001421 hyperglycemia Diseases 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 239000006228 supernatant Substances 0.000 description 4
- 241001070941 Castanea Species 0.000 description 3
- 235000014036 Castanea Nutrition 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 108010010234 HDL Lipoproteins Proteins 0.000 description 3
- 102000015779 HDL Lipoproteins Human genes 0.000 description 3
- 208000010473 Hoarseness Diseases 0.000 description 3
- XINCECQTMHSORG-UHFFFAOYSA-N Isoamyl isovalerate Chemical compound CC(C)CCOC(=O)CC(C)C XINCECQTMHSORG-UHFFFAOYSA-N 0.000 description 3
- 108010007622 LDL Lipoproteins Proteins 0.000 description 3
- 102000007330 LDL Lipoproteins Human genes 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 241000581835 Monodora junodii Species 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 3
- 235000001014 amino acid Nutrition 0.000 description 3
- 235000012000 cholesterol Nutrition 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 238000007619 statistical method Methods 0.000 description 3
- 239000011573 trace mineral Substances 0.000 description 3
- 235000013619 trace mineral Nutrition 0.000 description 3
- 210000001260 vocal cord Anatomy 0.000 description 3
- 230000001755 vocal effect Effects 0.000 description 3
- 239000000811 xylitol Substances 0.000 description 3
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 3
- 235000010447 xylitol Nutrition 0.000 description 3
- 229960002675 xylitol Drugs 0.000 description 3
- 102100036475 Alanine aminotransferase 1 Human genes 0.000 description 2
- 108010082126 Alanine transaminase Proteins 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 108010023302 HDL Cholesterol Proteins 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 108010028554 LDL Cholesterol Proteins 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 2
- 229960001231 choline Drugs 0.000 description 2
- 210000000805 cytoplasm Anatomy 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000013325 dietary fiber Nutrition 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 208000017574 dry cough Diseases 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 2
- 208000011293 voice disease Diseases 0.000 description 2
- XWMMEBCFHUKHEX-MRTCRTFGSA-N (+)-Taraxasterol Chemical compound C([C@@]12C)C[C@H](O)C(C)(C)[C@@H]1CC[C@]1(C)[C@@H]2CC[C@H]2[C@@H]3[C@H](C)C(=C)CC[C@]3(C)CC[C@]21C XWMMEBCFHUKHEX-MRTCRTFGSA-N 0.000 description 1
- QMKPCZNFLUQTJZ-UHFFFAOYSA-N (4aR)-10c-Hydroxy-1t.2c.4ar.6at.6bc.9.9.12ac-octamethyl-(8atH.12btH.14acH.14btH)-docosahydro-picen Natural products CC1CCC2(C)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C QMKPCZNFLUQTJZ-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- 108010003415 Aspartate Aminotransferases Proteins 0.000 description 1
- 102000004625 Aspartate Aminotransferases Human genes 0.000 description 1
- 238000011740 C57BL/6 mouse Methods 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 206010013789 Dry throat Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 206010043521 Throat irritation Diseases 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- 206010057295 Vocal cord inflammation Diseases 0.000 description 1
- 235000007244 Zea mays Nutrition 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 235000014171 carbonated beverage Nutrition 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 229940089639 cornsilk Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 235000004280 healthy diet Nutrition 0.000 description 1
- 208000027498 hoarse voice Diseases 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000011785 micronutrient Substances 0.000 description 1
- 235000013369 micronutrients Nutrition 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000020124 milk-based beverage Nutrition 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001823 pruritic effect Effects 0.000 description 1
- NGFFRJBGMSPDMS-UHFFFAOYSA-N psi-Taraxasterol Natural products CC12CCC(O)C(C)(C)C1CCC1(C)C2CCC2C3C(C)C(C)=CCC3(C)CCC21C NGFFRJBGMSPDMS-UHFFFAOYSA-N 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000007115 recruitment Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- HUTYZQWCTWWXND-NCTFTGAASA-N taraxasterol Natural products C[C@H]1[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@H](O)[C@@]2(C)CCC1=C HUTYZQWCTWWXND-NCTFTGAASA-N 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 208000026844 throat symptom Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 102000014898 transaminase activity proteins Human genes 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- -1 vitamin a Chemical class 0.000 description 1
- 239000001231 zea mays silk Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3472—Compounds of undetermined constitution obtained from animals or plants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
本发明属于食品技术领域,具体涉及一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用。所述的降糖降脂组合物包含如下按质量份计的组分:盐藻提取液1~15份,荸荠提取物1~15份,苦菊提取物1~15份和玉米须提取物1~15份。本发明还提供了一种包含上述降糖降脂组合物的饮品。本发明提供的降糖降脂组合物不仅具有补充维生素、矿物质和氨基酸等营养物质,从而起到调节新陈代谢、增强机体免疫力和抗病力的作用,而且具有显著降血脂降血脂的功效,对咽炎、咽喉炎等嗓音性疾病具有很好的预防和食疗作用。本发明提供的饮品为当前市场提供了一种集营养和食疗作用的保健饮品,克服了当前市场饮品领域的营养和功能性单一的问题。
Description
技术领域
本发明属于食品技术领域,具体涉及一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用。
背景技术
维生素是一系列有机化合物的总称,是生物体所需的微量营养成分。维生素一般又无法由生物体自己生产,需要通过饮食等手段获得。维生素不能像糖类、蛋白质及脂肪那样产生能量,但在细胞代谢活动中起着重要的调节作用。人体所需的维生素有多种,缺乏维生素可导致严重的健康问题。当前虽有多种维生素类药物,但存在维生素种类单一和过量摄取维生素中毒等不足。因此,依靠食物来源提供维生素显得更加健康和科学。
高血压、高血脂和高血糖俗称“三高症”已成为人类致命的的“头号杀手”,而高血糖可以引起糖尿病,高血脂可以引起血管栓塞等心脑血管疾病。一旦患上高血糖高血脂,患者只能靠长期服用降血脂降血糖药来治疗,不但对身体造成极大伤害,而且还会导致身体机能不断下降。世界卫生组织曾经明确提出,防止心血管病的第一道防线就是减少“三高”和控制“三高”。其中,科学健康饮食是最为经济、最为直接和发挥效果较好的途径之一。
盐藻提取液是从新型营养源盐藻细胞中提取的,其富含人体健康所需的多种天然类胡萝卜素、叶酸、维生素a、维生素e、亚麻酸、亚油酸、卵磷脂、岩藻多糖、膳食纤维等营养元素,同时含有钙、铁、锌、硒等70多种人体所需的矿物质及微量元素。此外,盐藻还富含18种氨基酸,其中8种是人体必需的。更为重要的是,盐藻所含营养元素的独特性和比例与人体的体液、细胞浆液相吻合,机体细胞可直接吸收各营养元素和物质,吸收效率高,补充营养效果好。不仅如此,盐藻具有一定降糖降脂效果,是一种营养兼功能性的食品原料。
祖国医学认为玉米须性味甘淡而平,入肝、肾、膀胱经,有利尿消肿、平肝利胆的功能。玉米须不仅含有人体所需的多种营养成分,而且具有显著的利尿、降血糖、增强免疫力等功效。荸荠中的磷含量是所有茎类蔬菜中含量最高的,磷元素促进体内的糖、脂肪、蛋白质三大物质的代谢,调节酸碱平衡和促进机体新陈代谢。同时荸荠具有清热泻火的良好功效,既可清热生津,又可补充营养。此外,荸荠中含有一种抗菌成分,对常见的金黄色葡萄球菌、大肠杆菌及绿脓杆菌均有一定的抑制作用。苦菊中富含多种维生素、氨基酸和微量元素,膳食纤维较高,还含有腊醇、胆碱、酒石酸、苦味素等化学物质,在增强人体机体抵抗力方面效果显著。作用明显。苦菊中含有蒲公英甾醇、胆碱等成分,对数十种病原菌具有杀灭和抑制作用,能够应用于多种炎症性疾病的治疗和预防。
发明内容
为了克服现有技术的不足和缺点,本发明的首要目的在于提供一种降糖降脂组合物。
本发明的另一目的在于提供上述降糖降脂组合物的制备方法。
本发明的再一目的在于提供一种降糖降脂饮品,该饮品包含上述降糖降脂组合物。
本发明的第四个目的在于提供上述降糖降脂组合物和降糖降脂饮品的应用。
本发明的目的通过下述技术方案实现:
一种降糖降脂组合物,包含如下按质量份计的组分:
所述的降糖降脂组合物,优选包含如下按质量份计的组分:
所述的降糖降脂组合物的制备方法,包含如下步骤:
(1)新鲜盐藻采用高压破碎后,固液分离,得到盐藻粗提取液;新鲜荸荠果皮分离后,荸荠果皮采用沸水浴冷凝回流,得到荸荠果皮粗提取液;荸荠果肉匀浆后加入冷水中浸泡提取,固液分离,得到荸荠果肉粗提取液,合并荸荠果皮粗提取液和荸荠果肉粗提取液,得到荸荠粗提取液;新鲜苦菊和新鲜玉米须匀浆后分别加入冷水中浸泡提取,固液分离,得到苦菊粗提取液和玉米须粗提取液;
(2)将步骤(1)制得的盐藻粗提取液、荸荠粗提取液、苦菊粗提取液和玉米粗须提取液分别低温静置,去除沉淀;浓缩,除菌,得到盐藻提取物、荸荠提取物、苦菊提取物和玉米须提取物;
(3)将步骤(2)制得的盐藻提取物、荸荠提取物、苦菊提取物和玉米须提取物按照配比混合均匀后静置去除沉淀;高压均质化,得到降糖降脂组合物;
步骤(1)中所述的新鲜盐藻优选为对数生长期的绿色盐藻;
步骤(1)中所述的新鲜荸荠优选为皮薄肉多、无破损的新鲜荸荠;
步骤(1)中所述的新鲜苦菊优选为新鲜采摘、茎叶挺拔、水分饱满的苦菊;
步骤(1)中所述的新鲜玉米须收取未成熟的青涩玉米须;
步骤(1)中所述的新鲜荸荠、新鲜苦菊和新鲜玉米须优选经过如下预处理:除杂、清洗、沥干;
步骤(1)中所述的高压破碎的条件优选为压力50~100MPa;
步骤(1)中所述的新鲜盐藻采用高压破碎后,固液分离的方式优选为:新鲜盐藻采用高压破碎后,4000~8000rpm离心4~10min;
步骤(1)中所述的沸水浴冷凝回流的条件优选为:沸水浴冷凝回流提取2~3次,每次0.5~3h,水的用量为荸荠果皮体积的2~5倍;
步骤(1)中所述的荸荠果肉匀浆后加入冷水中浸泡提取的条件优选为:冷水的用量优选为匀浆后的荸荠果肉体积的2~5倍,浸泡的时间优选为4~6h;冷水的温度优选为2~6℃;
步骤(1)中所述的苦菊和玉米须匀浆后分别加入冷水中浸泡提取提取的条件优选为:冷水的用量优选为匀浆后的苦菊或玉米须体积的1~5倍,浸泡的时间优选为4~6h;冷水的温度优选为2~6℃;
所述的低温静置的条件优选为2~6℃静置8~16h;
步骤(2)中所述的浓缩优选采用低温干燥仪进行;
步骤(2)中所述的浓缩优选浓缩至原体积的1/3~1/10;
步骤(2)中所述的除菌优选为微米级滤膜过滤除菌;
步骤(3)中所述的静置的时间优选为4~12h;
步骤(3)中所述的高压均质化的条件优选为压力10~50MPa;
所述的降糖降脂组合物在制备降糖降脂食品和饮品中的应用;
一种降糖降脂饮品,包含上述降糖降脂组合物;
所述的降糖降脂饮品,优选包含如下按质量份计的组分:
降糖降脂组合物 1~10份;
水 补足100份;
所述的降糖降脂饮品还包含酸味剂、甜味剂、香味剂和其它系列食品添加剂中的至少一种;
所述的降糖降脂饮品的制备方法,包含如下步骤:
将上述降糖降脂饮品的各组分混合均匀,得到降糖降脂饮品;
所述的降糖降脂饮品可进一步灭菌、罐装和封口,可得到成品降糖降脂饮品;
所述的降糖降脂饮品可压入CO2气体或加入其它乳品,得到碳酸性饮料或乳品饮料;
本发明相对于现有技术具有如下的优点及效果:
(1)本发明提供的降糖降脂组合物及其饮品利用营养丰富的盐藻作为原料之一,其富含多种维生素、矿物质和不饱和脂肪酸等元素,具有调节机体体质、增强免疫力的营养保健作用,组分盐藻提取液与人体的体液、细胞浆液相吻合,人体吸收效率高。与荸荠提取液、苦菊提取液和玉米须提取液复配,营养成分更加丰富,抗氧化和清除自由基能力等生物活性更强。
(2)本发明提供的降糖降脂组合物及其饮品具有显著的降糖、降脂作用,通过动物实验发现,该组合物降糖降脂效果显著高于单独组方效果,降糖降脂作用发挥出明显的“1+1>2”的叠加效应。含有该降糖降脂组合物的饮品具有抗氧化、增强机体免疫力和抗病力的功效,营养丰富、饮用可口,降糖降脂效果明显,对于高血糖高血脂患者提供了一种功能性的绿色食疗饮品。
(3)本发明提供的降糖降脂组合物所选取的各种原料来源均出自新鲜采摘或收集,与传统应用各种干燥原料不同,可保持其营养更加全面,抗氧化作用、清除自由基等生物活性最大。
(4)本发明提供的降糖降脂饮品富含各类维生素、微量元素、氨基酸和不饱和脂肪酸等营养物质,营养元素非常全面,口味独特、可口性强,克服了当前饮料领域营养单一的不足之处。
(5)本发明提供的降糖降脂组合物及其饮品通过各种组分的科学配伍,加工调配,通过实际生活应用发现,其对于嗓音性疾病,如咽炎、咽喉炎和声带炎等疾病具有明显的预防和食疗作用,使用群体效果明显优于未使用人群,能够明显减轻咽炎、咽喉炎和声带炎等症状,如异物感减弱,干、疼、痒症状减轻、声音嘶哑好转和利喉感增强等作用,加快疾病的恢复,缩短治疗周期。
(6)本发明提供的降糖降脂组合物不需要添加任何色素和防腐剂,即可制备各种颜色和色调的饮品。本发明巧妙利用了盐藻自身富含多种维生素的颜色和量的不同,同时配合苦菊和玉米须提取物的颜色,可以获得浅绿、青绿、墨绿、浅黄、橙黄和红色等多种颜色饮品,是一种天然理想的绿色食品色素,不会存在人工色素添加后的毒副作用,这种天然色素的应用,在国内外尚未见报道。
(7)本发明利用苦菊和荸荠含有抗多种病原菌的成份特性,无需添加人工防腐剂,即可达到抗菌效果和延长保质期的目的。
附图说明
图1是饮品组方对机体血糖血脂的控制效果图;其中,TC:总胆固醇;TG:甘油三酯;HDL-C:高密度脂蛋白;LDL-C:低密度脂蛋白;GLU:血糖;ALT:谷丙转氨酶;AST:谷草转氨酶;A:正常饲料组;B:高脂饲料组;C:添加盐藻提取物组;D:添加盐藻-荸荠提取物组;E:添加盐藻-荸荠-苦菊提取物组;F:添加盐藻-荸荠-苦菊-玉米须提取物组。
具体实施方式
下面结合实施例及附图对本发明作进一步详细的描述,但本发明的实施方式不限于此。
实施例中的份数均为质量份;
实施例1
(1)不同组份新鲜提取液的制备:
①将收集的对数生长期的新鲜绿色盐藻加入淡水调整细胞湿重为150g/L,采用高压细胞破碎仪破碎盐藻细胞,其中,压力采用100MPa;破碎后5000rpm离心5min收集上清液,得到盐藻粗提取液;
②皮薄肉多、无破损的新鲜荸荠采用自动削皮机削皮,荸荠果皮加入2倍体积的水混匀,进行沸水浴冷凝回流提取3h,纱布过滤后收集滤液;将第一次分离后的荸荠果皮渣继续加入2倍体积的水,沸水浴冷凝回流提取1.5h,纱布过滤后收集滤液;将第二次分离后的荸荠果皮渣继续加入2倍体积的水,沸水浴冷凝回流提取0.5h,纱布过滤后收集滤液,合并三次滤液,得到荸荠果皮粗提取液;荸荠果肉采用匀浆机1000rpm匀浆5min,然后加入2倍体积的4℃冷水浸泡4h;纱布过滤后收集滤液,得到荸荠果肉粗提取液,合并荸荠果皮粗提取液和荸荠果肉粗提取液,得到荸荠粗提取液;
③新鲜采摘、茎叶挺拔、水分饱满的苦菊和未成熟的青涩玉米须分别采用匀浆机1000rpm匀浆3min,然后分别加入等体积的4℃冷水浸泡4h,纱布过滤后收集滤液,弃杂质,得到苦菊粗提取液和玉米须粗提取液;
(2)提取液的浓缩处理:盐藻粗提取液、荸荠粗提取液、苦菊粗提取液和玉米须粗提取液分别在4℃低温静置10h,去除沉淀,得到澄清的提取液;提取液采用低温干燥仪进行进一步浓缩,浓缩至原体积的1/5,微米级滤膜过滤除菌,得到盐藻提取物、荸荠提取物、苦菊提取物和玉米须提取物;
(3)提取物的科学配伍及加工处理:分别取步骤(2)制得的盐藻提取物1份,荸荠提取物10份,苦菊提取物5份,玉米须提取物5份,四者提取液按照比例混合,搅拌均匀后静置沉淀5h,离心去除微量沉淀;然后采用40MPa的压力进行高压均质化,得到降糖降脂组合物;
(4)饮品的制备和罐装:取步骤(3)制得的降糖降脂组合物5份,柠檬酸0.2份、木糖醇0.2份、青苹果香精0.05份,不添加任何人工色素和防腐剂,补加纯净水至100份;经过搅拌、灭菌、罐装、封口加工工艺,得到成品降糖降脂饮品。
实施例2
(1)不同组份新鲜提取液的制备:
①将收集的对数生长期的新鲜绿色盐藻加入淡水调整细胞湿重为200g/L,采用高压细胞破碎仪破碎盐藻细胞,其中,压力采用80MPa;破碎后8000rpm离心4min收集液体,得到盐藻粗提取液;
②皮薄肉多、无破损的新鲜荸荠采用自动削皮机削皮,荸荠果皮加入3倍体积的水混匀,进行沸水浴冷凝回流提取2.5h,纱布过滤后收集滤液;将第一次分离后的荸荠果皮渣继续加入3倍体积的水,沸水浴冷凝回流提取1.0h,纱布过滤后收集滤液;将第二次分离后的荸荠果皮渣继续加入3倍体积的水,沸水浴冷凝回流提取0.5h,纱布过滤后收集滤液,合并三次滤液,得到荸荠果皮粗提取液;荸荠果肉采用匀浆机800rpm匀浆10min,然后加入3倍体积的2℃冷水浸泡5h,纱布过滤后收集滤液,得到荸荠果肉粗提取液,合并荸荠果皮粗提取液和荸荠果肉粗提取液,得到荸荠粗提取液;
③新鲜采摘、茎叶挺拔、水分饱满的苦菊和未成熟的青涩玉米须分别采用匀浆机800rpm匀浆5min,然后分别加入4倍体积的2℃冷水浸泡5h,纱布过滤后收集滤液,弃杂质,得到苦菊粗提取液和玉米须粗提取液;
(2)提取液的浓缩处理:盐藻粗提取液、荸荠粗提取液、苦菊粗提取液和玉米须粗提取液分别在2℃低温静置8h,去除沉淀,得到澄清的提取液;提取液采用低温干燥仪进行进一步浓缩,浓缩至原体积的1/10,微米级滤膜过滤除菌,得到盐藻提取物、荸荠提取物、苦菊提取物和玉米须提取物;
(3)提取物的科学配伍及加工处理:分别取步骤(2)制得的盐藻提取物5份,荸荠提取物8份,苦菊提取物7份,玉米须提取物6份,四者提取液按照比例混合,搅拌均匀后静置沉淀4h,离心去除微量沉淀;然后采用25MPa的压力进行高压均质化,得到降糖降脂组合物;
(4)饮品的制备和罐装:取步骤(3)制得的降糖降脂组合物10份,柠檬酸1.5份,木糖醇1.5份,青苹果香精0.1份,补加纯净水至100份;经过搅拌、灭菌、罐装、封口加工工艺,得到成品降糖降脂饮品。
实施例3
(1)不同组份新鲜提取液的制备:
①将收集的对数生长期的新鲜绿色盐藻加入淡水调整细胞湿重为150g/L,采用高压细胞破碎仪破碎盐藻细胞,其中,压力采用60MPa;破碎后4000rpm离心10min收集液体,得到盐藻粗提取液;
②皮薄肉多、无破损的新鲜荸荠采用自动削皮机削皮,荸荠果皮加入5倍体积的水混匀,进行沸水浴冷凝回流提取2h,纱布过滤后收集滤液;将第一次分离后的荸荠果皮渣继续加入5倍体积的水,沸水浴冷凝回流提取2h,纱布过滤后收集滤液;将第二次分离后的荸荠果皮渣继续加入5倍体积的水,沸水浴冷凝回流提取1h,纱布过滤后收集滤液,合并三次滤液,得到荸荠果皮粗提取液;荸荠果肉采用匀浆机500rpm匀浆15min,然后加入5倍体积的6℃冷水浸泡6h,纱布过滤后收集滤液,得到荸荠果肉粗提取液,合并荸荠果皮粗提取液和荸荠果肉粗提取液,得到荸荠粗提取液;
③新鲜采摘、茎叶挺拔、水分饱满的苦菊和未成熟的青涩玉米须分别采用匀浆机500rpm匀浆10min,然后分别加入5倍体积的6℃冷水浸泡6h,纱布过滤后收集滤液,弃杂质,得到苦菊粗提取液和玉米须粗提取液;
(2)提取液的浓缩处理:盐藻粗提取液、荸荠粗提取液、苦菊粗提取液和玉米须粗提取液分别在6℃低温静置16h,去除沉淀,得到澄清的提取液;提取液采用低温干燥仪进行进一步浓缩,浓缩至原体积的1/3,微米级滤膜过滤除菌,得到盐藻提取物、荸荠提取物、苦菊提取物和玉米须提取物;
(3)提取物的科学配伍及加工处理:分别取步骤(2)制得的盐藻提取物10份,荸荠提取物10份,苦菊提取物15份,玉米须提取物15份,四者提取液按照比例混合,搅拌均匀后静置沉淀12h,离心去除微量沉淀;然后采用35MPa的压力进行高压均质化,得到降糖降脂组合物;
(4)饮品的制备和罐装:取步骤(3)制得的降糖降脂组合物1份,柠檬酸1份,木糖醇0.5份,青苹果香精0.07份,补加纯净水至100份。经过搅拌、灭菌、罐装、封口加工工艺,得到成品降糖降脂饮品。
对比实施例1
(1)将收集的对数生长期的新鲜绿色盐藻加入淡水调整细胞湿重为150g/L,采用高压细胞破碎仪破碎盐藻细胞,其中,压力采用100MPa;破碎后5000rpm离心5min收集上清液,得到盐藻粗提取液;
(2)步骤(1)制得的盐藻粗提取液在4℃低温静置10h,去除沉淀,得到澄清的提取液;提取液采用低温干燥仪进行进一步浓缩,浓缩至原体积的1/5,微米级滤膜过滤除菌,得到盐藻提取物。
对比实施例2
(1)不同组份新鲜提取液的制备:
①将收集的对数生长期的新鲜绿色盐藻加入淡水调整细胞湿重为150g/L,采用高压细胞破碎仪破碎盐藻细胞,其中,压力采用100MPa;破碎后5000rpm离心5min收集上清液,得到盐藻粗提取液;
②皮薄肉多、无破损的新鲜荸荠采用自动削皮机削皮,荸荠果皮加入2倍体积的水混匀,进行沸水浴冷凝回流提取3h,纱布过滤后收集滤液;将第一次分离后的荸荠果皮渣继续加入2倍体积的水,沸水浴冷凝回流提取1.5h,纱布过滤后收集滤液;将第二次分离后的荸荠果皮渣继续加入2倍体积的水,沸水浴冷凝回流提取0.5h,纱布过滤后收集滤液,合并三次滤液,得到荸荠果皮粗提取液;荸荠果肉采用匀浆机1000rpm匀浆5min,然后加入2倍体积的4℃冷水浸泡4h;纱布过滤后收集滤液,得到荸荠果肉粗提取液,合并荸荠果皮粗提取液和荸荠果肉粗提取液,得到荸荠粗提取液;
(2)提取液的浓缩处理:盐藻粗提取液和荸荠粗提取液分别在4℃低温静置10h,去除沉淀,得到澄清的提取液;提取液采用低温干燥仪进行进一步浓缩,浓缩至原体积的1/5,微米级滤膜过滤除菌,得到盐藻提取物和荸荠提取物;
(3)提取物的配伍及加工处理:分别取步骤(2)制得的盐藻提取物1份,荸荠提取物10份,两者提取物按照比例混合,搅拌均匀后静置沉淀5h,离心去除微量沉淀;然后采用40MPa的压力进行高压均质化,得到盐藻-荸荠提取物组合物。
对比实施例3
①将收集的对数生长期的新鲜绿色盐藻加入淡水调整细胞湿重为150g/L,采用高压细胞破碎仪破碎盐藻细胞,其中,压力采用100MPa;破碎后5000rpm离心5min收集上清液,得到盐藻粗提取液;
②皮薄肉多、无破损的新鲜荸荠采用自动削皮机削皮,荸荠果皮加入2倍体积的水混匀,进行沸水浴冷凝回流提取3h,纱布过滤后收集滤液;将第一次分离后的荸荠果皮渣继续加入2倍体积的水,沸水浴冷凝回流提取1.5h,纱布过滤后收集滤液;将第二次分离后的荸荠果皮渣继续加入2倍体积的水,沸水浴冷凝回流提取0.5h,纱布过滤后收集滤液,合并三次滤液,得到荸荠果皮粗提取液;荸荠果肉采用匀浆机1000rpm匀浆5min,然后加入2倍体积的4℃冷水浸泡4h;纱布过滤后收集滤液,得到荸荠果肉粗提取液,合并荸荠果皮粗提取液和荸荠果肉粗提取液,得到荸荠粗提取液;
③新鲜采摘、茎叶挺拔、水分饱满的苦菊采用匀浆机1000rpm匀浆3min,然后加入等体积的4℃冷水浸泡4h,纱布过滤后收集滤液,弃杂质,得到苦菊粗提取液;
(2)提取液的浓缩处理:盐藻粗提取液、荸荠粗提取液和苦菊粗提取液分别在4℃低温静置10h,去除沉淀,得到澄清的提取液;提取液采用低温干燥仪进行进一步浓缩,浓缩至原体积的1/5,微米级滤膜过滤除菌,得到盐藻提取物、荸荠提取物和苦菊提取物;
(3)提取液的科学配伍及加工处理:分别取盐藻提取物1份,荸荠提取物10份,苦菊提取物5份,三者提取物按照比例混合,搅拌均匀后静置沉淀5h,离心去除微量沉淀;然后采用40MPa的压力进行高压均质化,得到盐藻-荸荠-苦菊提取物组合物。
效果实施例
(1)对机体的降糖降脂作用分析
利用高脂饮食诱导的小鼠肥胖模型,在该模型上求证降糖降脂组合物(实施例1制得)对机体血糖血脂的改善作用。购买5周龄雄性C57BL/6小鼠,实验设计为5个组,每组18只,实验前所有动物静养1周。5组小鼠分别为:A组,正常饲料组;B组,高脂饲料组;C组,添加盐藻提取物组(对比实施例1);D组,添加盐藻-荸荠提取物组合物组(对比实施例2);E组,添加盐藻-荸荠-苦菊提取物组合物组(对比实施例3);F组,添加盐藻-荸荠-苦菊-玉米须提取物组(实施例1制得的降糖降脂组合物)。小鼠高脂喂养2个月后,每两周记录小鼠生长体重,采血检测生化指标。主要检查指标包括甘油三酯、总胆固醇、低密度脂蛋白、高密度脂蛋白和血糖,连续监测6次,即高脂喂养持续三个月的时间。通过对检测数据的统计分析,F组的降糖降脂效果明显优于其它四组,且降糖降脂效果明显(表1、图1)。
表1降糖降脂组合物对机体血糖血脂的控制数据表
备注:TC,总胆固醇;TG,甘油三酯;HDL-C,高密度脂蛋白;LDL-C,低密度脂蛋白;GLU,血糖;ALT,谷丙转氨酶;AST,谷草转氨酶。A组,正常饲料组;B组,高脂饲料组;C组,添加盐藻提取液组;D组,添加盐藻-荸荠提取液组;E组,添加盐藻-荸荠-苦菊提取液组;F组,添加盐藻-荸荠-苦菊-玉米须提取液组。与A组比较,*P<0.05,**P<0.01,***P<0.001;与B组比较,ΔP<0.05,ΔΔP<0.01,ΔΔΔP<0.001。
(2)对咽炎、咽喉炎的预防和食疗效果
在新学期开学之际,在某学校招募经常上课的教师100名,招募标准为全部老师周一到周五上午和下午均有教学任务,观察时间为1个月。100名教师随机分为AB两组,每组50名。A组每位老师分发饮品3箱(每箱20瓶,每瓶550ml,实施例1制得的降糖降脂饮品),每天上午和下午上课时,均服用一瓶。B组每位老师每天自备白开水,上午和下午各550ml饮用水。随后每三天登记一次每位老师的咽炎、咽喉炎或嗓子有症状的发生情况。通过统计分析,结果表明该降糖降脂饮品对嗓音性疾病具有很好的预防效果,总体有效率达66%(表2)。
表2降糖降脂饮品对嗓音性疾病的预防作用
备注:出现症状指标包括咽炎、咽喉炎和声带炎等干、疼、痒症状发生和增强;声音嘶哑;干咳发生;异物感显著;吞咽疼痛或困难;发热等症状均属于统计范围。
在教学过程中,招募嗓音症状的老师和学生共计50名,包括嗓音嘶哑、嗓子干痒疼等症状、咽炎、咽喉炎等各种不适症状。随机分为两组,A组25名,每天上午和下午分别饮用实施例1制得的降糖降脂饮品550ml,统计服用后3、4、5和6天内的症状改善情况,每天登记改善效果。B组25名,没有服用该饮品,每天上午和下午饮用550ml白开水。通过对A、B组的实验结果统计分析,结果表明该饮品对于嗓音性疾病的有效缓解率为44%(表3)。
表3降糖降脂饮品对嗓音性疾病的食疗作用
备注:症状指标包括咽炎、咽喉炎和声带炎等干、疼、痒症状减轻;声音嘶哑好转;干咳消失;异物感减弱和利喉感增强等,均属于统计范围。
上述实施例为本发明较佳的实施方式,但本发明的实施方式并不受上述实施例的限制,其他的任何未背离本发明的精神实质与原理下所作的改变、修饰、替代、组合、简化,均应为等效的置换方式,都包含在本发明的保护范围之内。
Claims (9)
1.一种降糖降脂组合物,其特征在于包含如下按质量份计的组分:
盐藻提取液 1~15份;
荸荠提取物 1~15份;
苦菊提取物 1~15份;
玉米须提取物 1~15份;
所述的降糖降脂组合物的制备方法,包含如下步骤:
(1)新鲜盐藻采用高压破碎后,固液分离,得到盐藻粗提取液;新鲜荸荠果皮分离后,荸荠果皮采用沸水浴冷凝回流,得到荸荠果皮粗提取液;荸荠果肉匀浆后加入冷水中浸泡提取,固液分离,得到荸荠果肉粗提取液,合并荸荠果皮粗提取液和荸荠果肉粗提取液,得到荸荠粗提取液;新鲜苦菊和新鲜玉米须匀浆后分别加入冷水中浸泡提取,固液分离,得到苦菊粗提取液和玉米须粗提取液;
(2)将步骤(1)制得的盐藻粗提取液、荸荠粗提取液、苦菊粗提取液和玉米粗须提取液分别低温静置,去除沉淀;浓缩,除菌,得到盐藻提取物、荸荠提取物、苦菊提取物和玉米须提取物;
(3)将步骤(2)制得的盐藻提取物、荸荠提取物、苦菊提取物和玉米须提取物按照配比混合均匀后静置去除沉淀;高压均质化,得到降糖降脂组合物。
2.根据权利要求1所述的降糖降脂组合物,其特征在于包含如下按质量份计的组分:
盐藻提取液 1~10份;
荸荠提取物 8~10份;
苦菊提取物 5~15份;
玉米须提取物 5~15份。
3.根据权利要求1所述的降糖降脂组合物,其特征在于:
步骤(1)中所述的高压破碎的条件为压力50~100MPa。
4.根据权利要求1所述的降糖降脂组合物,其特征在于:
步骤(1)中所述的沸水浴冷凝回流的条件为:沸水浴冷凝回流提取2~3次,每次0.5~3h,水的用量为荸荠果皮体积的2~5倍。
5.根据权利要求1所述的降糖降脂组合物,其特征在于:
步骤(1)中所述的荸荠果肉匀浆后加入冷水中浸泡提取的条件为:冷水的用量为匀浆后的荸荠果肉体积的1~5倍,浸泡的时间为4~6h;冷水的温度为2~6℃。
6.根据权利要求1所述的降糖降脂组合物,其特征在于:
步骤(1)中所述的苦菊和玉米须匀浆后分别加入冷水中浸泡提取的条件为:冷水的用量为匀浆后的苦菊或玉米须体积的2~5倍,浸泡的时间为4~6h;冷水的温度为2~6℃。
7.权利要求1或2所述的降糖降脂组合物在制备降糖降脂食品和饮品中的应用。
8.一种降糖降脂饮品,其特征在于包含权利要求1或2所述的降糖降脂组合物。
9.根据权利要求8所述的降糖降脂饮品,其特征在于包含如下按质量份计的组分:
降糖降脂组合物 1~10份,水补足100份。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711471889.1A CN108125240B (zh) | 2017-12-29 | 2017-12-29 | 一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711471889.1A CN108125240B (zh) | 2017-12-29 | 2017-12-29 | 一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108125240A CN108125240A (zh) | 2018-06-08 |
CN108125240B true CN108125240B (zh) | 2021-05-11 |
Family
ID=62393547
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201711471889.1A Active CN108125240B (zh) | 2017-12-29 | 2017-12-29 | 一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108125240B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115997930B (zh) * | 2023-01-13 | 2024-04-05 | 时代生物科技(深圳)有限公司 | 一种具有减脂功能的组合物及其制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100537532C (zh) * | 2007-08-24 | 2009-09-09 | 清华大学 | 一种从杜氏盐藻中提取类胡萝卜素和食用甘油的方法 |
CN102038873A (zh) * | 2009-10-09 | 2011-05-04 | 吴海洋 | 治疗高血压的水饮配方及其配制方法 |
CN101849692B (zh) * | 2010-05-26 | 2012-06-27 | 山东好当家海洋发展股份有限公司 | 一种降血糖饮品及其制备方法 |
CN101946944B (zh) * | 2010-08-18 | 2012-10-17 | 齐齐哈尔医学院 | 一种玉米须水及其制备方法 |
CN102318862B (zh) * | 2011-07-20 | 2013-05-29 | 张志年 | 一种苦菊菜饮料及其制备方法 |
CN103478845B (zh) * | 2013-09-06 | 2016-04-06 | 哈尔滨玉农源食品有限公司 | 一种玉米须浸提浓缩液及其制备方法 |
CN103719993A (zh) * | 2013-12-27 | 2014-04-16 | 陈青 | 一种玉米须降糖饮品及其制备方法 |
CN104921009A (zh) * | 2015-05-30 | 2015-09-23 | 福建万亿店中店电子商务有限责任公司 | 具有降脂护肝功效的复合果皮提取物 |
CN106107334A (zh) * | 2016-06-20 | 2016-11-16 | 吉林农业大学 | 一种玉米须健康饮品及其生产方法 |
CN106173715A (zh) * | 2016-07-21 | 2016-12-07 | 唐翔 | 一种马蹄汁的制备工艺 |
CN106620352A (zh) * | 2017-01-22 | 2017-05-10 | 杨挺 | 一种降血糖的玉米须口服液的制备方法 |
-
2017
- 2017-12-29 CN CN201711471889.1A patent/CN108125240B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN108125240A (zh) | 2018-06-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101507459B (zh) | 一种橄榄速溶茶及其制备方法 | |
CN102578648B (zh) | 一种果汁饮料 | |
KR101541516B1 (ko) | 누에와 뽕나무잎과 상지(桑枝)를 주원료로한 이온미네랄 건강음료의 제조방법 | |
US9950024B2 (en) | Traditional Chinese medicine composition and the use thereof | |
CN101292762B (zh) | 一种籽瓜饮料及其加工工艺 | |
CN106213101A (zh) | 一种发酵型果蔬汁 | |
CN104305427A (zh) | 葡萄红茶菌饮料 | |
CN102429305A (zh) | 一种缓解视疲劳的枸杞功能饮料 | |
CN103704816A (zh) | 一种山楂果醋及其制作方法 | |
KR20200040205A (ko) | 발효숙성 노니와 코코넛 슈가를 포함하는 발효 노니 식초, 이를 포함하는 식초음료 및 이의 제조방법 | |
CN103361223A (zh) | 复合保健果酒及其制作方法 | |
CN100563453C (zh) | 枸杞子奶茶的生产方法 | |
CN104382129A (zh) | 一种甜玉米红茶菌饮品 | |
CN103609695A (zh) | 降压祛火的酸奶及其制备方法 | |
CN108125240B (zh) | 一种降糖降脂组合物、降糖降脂饮品及其制备方法和应用 | |
KR101525478B1 (ko) | 숙취해소용 식품 조성물 | |
CN107557254B (zh) | 一种荔枝玫瑰酒和制备方法及补益气血与抗氧化应用 | |
CN107557204B (zh) | 一种混酿荔枝玫瑰酒及其制备方法 | |
CN105029553A (zh) | 一种果汁蛋钙中药保健饮料及其制备方法 | |
CN103610184A (zh) | 一种能提神的新型饮料 | |
CN104287045A (zh) | 一种大清枣茶菌饮品 | |
CN105325823A (zh) | 格瓦斯饮料及其制备方法 | |
CN104432367A (zh) | 一种以墨米为原料的生物型饮料及其制备方法 | |
CN104170970A (zh) | 一种桑叶酸奶及其制备方法 | |
CN113773937A (zh) | 一种具有保健养生作用的芦笋饮料 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20210415 Address after: 450000 room 2908, Jiayi Oriental building, intersection of Zhongxing South Road and Fulu street, Zhengzhou area (Zhengdong), Henan pilot Free Trade Zone, Zhengzhou City, Henan Province Applicant after: Sodote Medical Bioengineering Co.,Ltd. Address before: 471000 No. 48, Xiyuan Road, Jianxi District, Henan, Luoyang Applicant before: HENAN University OF SCIENCE AND TECHNOLOGY |
|
TA01 | Transfer of patent application right | ||
GR01 | Patent grant | ||
GR01 | Patent grant |