CN107903263B - 一种帕布昔利布中间体的合成方法 - Google Patents
一种帕布昔利布中间体的合成方法 Download PDFInfo
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- CN107903263B CN107903263B CN201711463418.6A CN201711463418A CN107903263B CN 107903263 B CN107903263 B CN 107903263B CN 201711463418 A CN201711463418 A CN 201711463418A CN 107903263 B CN107903263 B CN 107903263B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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CN107903263A CN107903263A (zh) | 2018-04-13 |
CN107903263B true CN107903263B (zh) | 2019-11-12 |
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CN109320511A (zh) * | 2018-10-26 | 2019-02-12 | 广安凯特制药有限公司 | 一种高纯度帕博西尼中间体产品及其制备方法 |
CN111362939B (zh) * | 2020-04-26 | 2021-08-03 | 山东梅奥华卫科技有限公司 | 一种帕布昔利布母核结构化合物的制备方法 |
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JP6282759B2 (ja) * | 2014-04-14 | 2018-02-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Rorガンマのモジュレーターとしての化合物 |
JP2015231988A (ja) * | 2014-05-12 | 2015-12-24 | 大正製薬株式会社 | 2−ピリドン化合物 |
CN104447739B (zh) * | 2014-11-07 | 2016-02-17 | 郑州泰基鸿诺药物科技有限公司 | 一种氘代Palbociclib衍生物、制备方法及应用 |
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Denomination of invention: A synthetic method of pabcilib intermediate Effective date of registration: 20211207 Granted publication date: 20191112 Pledgee: Qilu bank Limited by Share Ltd. Ji'nan science and technology innovation center sub branch Pledgor: SHANDONG BOYUAN PHARMACEUTICAL Co.,Ltd. Registration number: Y2021980014223 |
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Address after: 251400 No. 12, Taixing East Street, Jibei Economic Development Zone, Jiyang District, Jinan City, Shandong Province Patentee after: Shandong Baoyuan Pharmaceutical Co.,Ltd. Address before: Strong in Jiyang County of Ji'nan City, 251400 North Street, Shandong Province Economic Development Zone Patentee before: SHANDONG BOYUAN PHARMACEUTICAL Co.,Ltd. |