CN107617056A - A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer - Google Patents
A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer Download PDFInfo
- Publication number
- CN107617056A CN107617056A CN201710903675.0A CN201710903675A CN107617056A CN 107617056 A CN107617056 A CN 107617056A CN 201710903675 A CN201710903675 A CN 201710903675A CN 107617056 A CN107617056 A CN 107617056A
- Authority
- CN
- China
- Prior art keywords
- parts
- lung cancer
- chinese medicine
- medicine composition
- ginseng
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer, including extracting dendrobium candidum with ethanol, ginseng, pseudo-ginseng, medicinal extract is obtained after obtained ethanol extract is concentrated, extraction by steam distillation Moschus, cow-bezoar, volatile oil is obtained after peppermint, the aqueous solution and the dregs of a decoction, the dregs of a decoction and Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, decocted after golden cypress mixing and obtain filtrate, the aqueous solution and filtrate are concentrated to give clear cream after merging, clear cream crushes to obtain powdered extract powder after being dried under reduced pressure after merging with medicinal extract, by magnesium stearate, volatile oil and powdered extract powder are well mixed, filling hard shell capsules after granulation, produce the Chinese medicine composition for auxiliary treatment lung cancer.Chinese medicine composition produced by the present invention for auxiliary treatment lung cancer can be used in combination with other Remedies for lung cancer, and reduce drug side-effect.
Description
Technical field
The present invention relates to the preparation of a kind of Chinese medicine preparation, more particularly to a kind of Chinese medicine composition for auxiliary treatment lung cancer
Method, belong to technical field of traditional Chinese pharmacology.
Background technology
Maximum one category in Dendrobium orchid family, including about 1200 various plants, it is distributed mainly on Tropical Asian, sub- heat
Some island in band, Australia and the Pacific Ocean.China there are about 63 kinds, about 39 kinds of hyoscine.In terms of vertical height, height above sea level
100~3000 meters of height is all distributed, and most of China is distributed in the ground such as southwest, south China, Taiwan, and south China and East China have
Many cultivation bases, Zhejiang Province is more using dendrobium candidum especially, and Yunnan Province and Hunan Province are then more using the gold fork stem of noble dendrobium.Iron sheet stone
Dry measure used in former times, gold fork stem of noble dendrobium etc. are the important traditional Chinese medicines in China, and its medical value is praised highly by the successive dynasties.Medicinal dendrobium mainly contains stone
The various active composition such as dry measure used in former times polysaccharide, alkaloid, there is nourishing Yin and clearing heat, the beneficial stomach that promotes the production of body fluid, the multiple efficacies such as moisten the lung and relieve the cough.Modern pharmacology
Research shows that it also has and improves the functions such as immunity of organisms, antitumor and preventing and treating cataract.And dendrobium candidum is on the stem of noble dendrobium
Product, ranked because of its special living environment and distinguished nourishing effects first of " Chinese nine big celestial grass ".
Into 21 century, the situation increased sharply year by year is presented in the incidence of disease of cancer, and China has 8550 people to suffer from as cancer daily
Person.In numerous tumor invasion crowds, the morbidity and mortality of lung cancer all occupy the first.Lung cancer is that one kind betides branch gas
The malignant tumour of pipe mucous membrane and alveolar wall.Theory of traditional Chinese medical science thinks, " healthy tendency deposit in, heresy can not be done ", and it is to form lung cancer that the positive deficiency of vital energy, which declines,
Basis.Traditional Chinese medical science scholar, which studies, to be found, the lung-dryness syndrome due to yin deficiency, lung heat impairment of yin are the internal conditions for promoting lung cancer to occur.Chinese medicine iron sheet stone
Dry measure used in former times is the good merchantable brand of enriching yin, has the effect of reinforcing stomach reg fluid, nourishing Yin and clearing heat.Modern pharmacology research shows that fresh dendrobium candidum plays
Antitumaous effect, the alkaloid and polysaccharide contained with it have stronger immunoregulatory activity, can be obviously improved peripheral leukocytes,
And tumor promotion can be suppressed, improve thymus gland and spleen index.
In the prior art, using Amrubicin, by being used in combination Amrubicin Hydrochloride and cis-platinum etc., but Amrubicin
There is side effect with the treatment of the drug combinations of other Remedies for lung cancer to lung cancer.
The content of the invention
It is an object of the invention to provide a kind of preparation method of the Chinese medicine composition for auxiliary treatment lung cancer.
In order to achieve the above objects and other related objects, technical scheme provided by the invention is：One kind is used for auxiliary treatment
The preparation method of the Chinese medicine composition of lung cancer, the composition of raw materials of the Chinese medicine composition for auxiliary treatment lung cancer is including following
The material of parts by weight：
35~55 parts of dendrobium candidum；
23~46 parts of Moschus；
20~45 parts of ginseng；
15~45 parts of cow-bezoar；
13~28 parts of pseudo-ginseng；
20~39 parts of peppermint；
20~35 parts of Radix Angelicae Sinensis；
14~28 parts of propolis；
12~26 parts of the tuber of dwarf lilyturf；
2~9 parts of borneol；
3~11 parts of fig；
10~18 parts of golden cypress；
The preparation method of the Chinese medicine composition for auxiliary treatment lung cancer comprises the following steps：
The first step：Dendrobium candidum, ginseng and pseudo-ginseng are taken, the ethanol that the volume fraction for adding 2~6 times of volumes is 60~75%, backflow carries
Take 3~6 times, 1~3 hour every time, merge ethanol extract, the filtrate obtained after filtering be condensed into relative density for 1.15~
1.45 medicinal extract, relative density measure when 60 DEG C；
Second step：Moschus, cow-bezoar and peppermint are taken, adds the water of 3~5 times of volumes to soak 4~8 hours, steam distillation 2~6 hours,
Condensate liquid and the dregs of a decoction are obtained, the condensate liquid obtains volatile oil and the aqueous solution after water-oil separating；
3rd step：The dregs of a decoction obtained by second step are mixed with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and thereto
The decocting for adding 6~12 times of volumes is boiled 2~4 times, 1~3 hour every time, collecting decoction, is filtered and is collected filtrate；
4th step：The aqueous solution that second step obtains is merged with the filtrate that the 3rd step is collected, be condensed into relative density for 1.15~
1.45 clear cream, relative density measure when 60 DEG C；
5th step：The clear cream that 4th step obtains is merged with the medicinal extract that the first step obtains, crushed after being dried under reduced pressure, crosses 50 ~ 100 mesh
Powdered extract powder is obtained after sieve；
6th step：The powdered extract powder that the volatile oil and the 5th step that magnesium stearate, second step are obtained obtain is well mixed, granulation
Filling hard shell capsules afterwards, produce the Chinese medicine composition for auxiliary treatment lung cancer.
Preferably technical scheme is：The composition of raw materials of the Chinese medicine composition for auxiliary treatment lung cancer includes following heavy
Measure the material of part：
45 parts of dendrobium candidum；
38 parts of Moschus；
35 parts of ginseng；
36 parts of cow-bezoar；
22 parts of pseudo-ginseng；
32 parts of peppermint；
28 parts of Radix Angelicae Sinensis；
20 parts of propolis；
21 parts of the tuber of dwarf lilyturf；
7 parts of borneol；
8 parts of fig；
12 parts of golden cypress.
Preferably technical scheme is：The dendrobium candidum is monarch drug in a prescription, and Moschus, ginseng, cow-bezoar, pseudo-ginseng are ministerial drug, peppermint, when
Return, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress are adjuvant.
Preferably technical scheme is：The preparation method of the Chinese medicine composition for auxiliary treatment lung cancer includes following step
Suddenly：
The first step：Dendrobium candidum, ginseng and pseudo-ginseng are taken, the ethanol that the volume fraction for adding 4 times of volumes is 70%, refluxing extraction 5 times,
2 hours every time, merge ethanol extract, the filtrate obtained after filtering is condensed into the medicinal extract that relative density is 1.35, relative density
Measured when 60 DEG C；
Second step：Moschus, cow-bezoar and peppermint are taken, adds the water of 4 times of volumes to soak 6 hours, steam distillation 4 hours, is condensed
Liquid and the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating；
3rd step：The dregs of a decoction obtained by second step are mixed with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and thereto
The decocting for adding 9 times of volumes is boiled 3 times, 2 hours every time, collecting decoction, is filtered and is collected filtrate；
4th step：The aqueous solution that second step obtains is merged with the filtrate that the 3rd step is collected, be condensed into relative density be 1.3 it is clear
Cream, relative density measure when 60 DEG C；
5th step：The clear cream that 4th step obtains is merged with the medicinal extract that the first step obtains, crushed after being dried under reduced pressure, after crossing 80 mesh sieves
Obtain powdered extract powder；
6th step：The powdered extract powder that the volatile oil and the 5th step that magnesium stearate, second step are obtained obtain is well mixed, granulation
Filling hard shell capsules afterwards, produce the Chinese medicine composition for auxiliary treatment lung cancer.
Because above-mentioned technical proposal is used, the present invention this have the advantage that compared with prior art：
1st, the Chinese medicine composition produced by the present invention for auxiliary treatment lung cancer can be used in combination with other Remedies for lung cancer, and
Reduce drug side-effect.
2nd, Chinese medicine composition produced by the present invention is capable of the immune system of body, provides growth factor for T cell, holds
Row cellular immune function.
Embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this implementation
Content disclosed by example understands other advantages and effect of the present invention easily.
Embodiment 1：A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer
A kind of Chinese medicine composition for auxiliary treatment lung cancer, by weight, the composition of raw materials of the Chinese medicine composition includes：
35 parts of dendrobium candidum, 23 parts of Moschus, 20 parts of ginseng, 15 parts of cow-bezoar, 13 parts of pseudo-ginseng, 20 parts of peppermint, 20 parts of Radix Angelicae Sinensis, 14 parts of propolis,
12 parts of the tuber of dwarf lilyturf, 2 parts of borneol, 3 parts of fig, 10 parts of golden cypress.
The dendrobium candidum is monarch drug in a prescription, and Moschus, ginseng, cow-bezoar, pseudo-ginseng are ministerial drug, peppermint, Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, ice
Piece, fig, golden cypress are adjuvant.
Preparation method comprises the following steps：
（1）Dendrobium candidum, ginseng, pseudo-ginseng are taken, the ethanol that the volume fraction for adding 2 times of volumes is 60%, refluxing extraction 3 times, every time 1
Hour, merge ethanol extract, the filtrate obtained after filtering is condensed into the medicinal extract that relative density is 1.15, and relative density is in 60 DEG C
When measure, ethanol is reclaimed in concentration process.
（2）Moschus, cow-bezoar, peppermint are taken, adds the water of 3 times of volumes to soak 4 hours, steam distillation 2 hours, obtains condensate liquid
And the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating.
（3）By step（2）The gained dregs of a decoction mix with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and thereto
The decocting for adding 6 times of volumes is boiled 2 times, 1 hour every time, collecting decoction, filtering, collects filtrate.
（4）By step（2）The aqueous solution and step of collection（3）The filtrate of collection merges, and is condensed into relative density as 1.15
Clear cream, relative density measures when 60 DEG C.
（5）By step（4）The clear cream and step of acquisition（1）The medicinal extract of acquisition merges, and 50 mesh are crossed after being crushed after being dried under reduced pressure
Sieve, obtains powdered extract powder.
（6）Take magnesium stearate, step（2）The volatile oil of collection, step（5）The powdered extract powder mixing of acquisition, is mixed, system
Grain, whole grain, filling hard shell capsules, polish, examine, packing, you can be made.The amount of magnesium stearate is the 2% of product gross weight.
Embodiment 2：A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer
A kind of Chinese medicine composition for auxiliary treatment lung cancer, by weight, the composition of raw materials of the Chinese medicine composition includes：
45 parts of dendrobium candidum, 38 parts of Moschus, 35 parts of ginseng, 36 parts of cow-bezoar, 22 parts of pseudo-ginseng, 32 parts of peppermint, 28 parts of Radix Angelicae Sinensis, 20 parts of propolis,
21 parts of the tuber of dwarf lilyturf, 7 parts of borneol, 8 parts of fig, 12 parts of golden cypress.
The dendrobium candidum is monarch drug in a prescription, and Moschus, ginseng, cow-bezoar, pseudo-ginseng are ministerial drug, peppermint, Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, ice
Piece, fig, golden cypress are adjuvant.
Preparation method comprises the following steps：
（1）Dendrobium candidum, ginseng, pseudo-ginseng are taken, the ethanol that the volume fraction for adding 4 times of volumes is 70%, refluxing extraction 5 times, every time 2
Hour, merge ethanol extract, the filtrate obtained after filtering is condensed into the medicinal extract that relative density is 1.35, and relative density is in 60 DEG C
When measure, ethanol is reclaimed in concentration process.
（2）Moschus, cow-bezoar, peppermint are taken, adds the water of 3 times of volumes to soak 6 hours, steam distillation 4 hours, obtains condensate liquid
And the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating.
（3）By step（2）The gained dregs of a decoction mix with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and thereto
The decocting for adding 9 times of volumes is boiled 3 times, 2 hours every time, collecting decoction, filtering, collects filtrate.
（4）By step（2）The aqueous solution and step of collection（3）The filtrate of collection merges, and it is 1.3 to be condensed into relative density
Clear cream, relative density measure when 60 DEG C.
（5）By step（4）The clear cream and step of acquisition（1）The medicinal extract of acquisition merges, and 80 mesh are crossed after being crushed after being dried under reduced pressure
Sieve, obtains powdered extract powder.
（6）Take magnesium stearate, step（2）The volatile oil of collection, step（5）The powdered extract powder mixing of acquisition, is mixed, system
Grain, whole grain, filling hard shell capsules, polish, examine, packing, you can be made.The amount of magnesium stearate is the 5% of product gross weight.
Embodiment 3：A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer
A kind of Chinese medicine composition for auxiliary treatment lung cancer, by weight, the Chinese medicine composition includes：Dendrobium candidum 55
Part, 46 parts of Moschus, 45 parts of ginseng, 45 parts of cow-bezoar, 28 parts of pseudo-ginseng, 39 parts of peppermint, 35 parts of Radix Angelicae Sinensis, 28 parts of propolis, 26 parts of the tuber of dwarf lilyturf,
9 parts of borneol, 11 parts of fig, 18 parts of golden cypress.
The dendrobium candidum is monarch drug in a prescription, and Moschus, ginseng, cow-bezoar, pseudo-ginseng are ministerial drug, peppermint, Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, ice
Piece, fig, golden cypress are adjuvant.
Preparation method comprises the following steps：
（1）Dendrobium candidum, ginseng, pseudo-ginseng are taken, the ethanol that the volume fraction for adding 6 times of volumes is 75%, refluxing extraction 6 times, every time 3
Hour, merge ethanol extract, the filtrate obtained after filtering is condensed into the medicinal extract that relative density is 1.45, and relative density is in 60 DEG C
When measure, ethanol is reclaimed in concentration process.
（2）Moschus, cow-bezoar, peppermint are taken, adds the water of 5 times of volumes to soak 8 hours, steam distillation 6 hours, obtains condensate liquid
And the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating.
（3）By step（2）The gained dregs of a decoction mix with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and thereto
The decocting for adding 12 times of volumes is boiled 4 times, 3 hours every time, collecting decoction, filtering, collects filtrate.
（4）By step（2）The aqueous solution and step of collection（3）The filtrate of collection merges, and is condensed into relative density as 1.45
Clear cream, relative density measures when 60 DEG C.
（5）By step（4）The clear cream and step of acquisition（1）The medicinal extract of acquisition merges, and 100 mesh are crossed after being crushed after being dried under reduced pressure
Sieve, obtains powdered extract powder.
（6）Take magnesium stearate, step（2）The volatile oil of collection, step（5）The powdered extract powder mixing of acquisition, is mixed, system
Grain, whole grain, filling hard shell capsules, polish, examine, packing, you can be made.The amount of magnesium stearate is the 7% of product gross weight.
Zooscopy is carried out to the Chinese medicine composition for auxiliary treatment lung cancer that the present invention prepares：
Experimental animal：Mouse is cleaned, female, 14~16g of weight, is provided by Shanghai Si Laike Experimental Animal Centers；Lung cancer tumor strain
Introduced by Chinese Academy of Sciences's Shanghai medicine.
Medicine：Commercially available syklofosfamid ampoule, the Chinese medicine composition of the present invention for auxiliary treatment lung cancer.
Model is established：It will pass on 3 times, be inoculated with after the murine lung cancer cell recovery of liquid nitrogen cryopreservation.Take well-grown lung cancer
Mouse two, strips tumor mass, and homogenate is made 1 × 107mL-1Cell suspension, be inoculated in respectively cleaning mouse right armpit it is subcutaneous, often
The 7th day after 0.2mL. tumor inoculations, tumor mass occurs, and starts to be grouped.After being inoculated with the 16th day, apocleisis occurs in mouse, activity is reduced,
Exhaustion, start to be administered.
Packet and administration：30 mouse are randomly divided into 3 groups, i.e. model group, endoxan group and for auxiliary treatment lung
The Chinese medicine composition group of cancer.The daily 30mL/kg gavages feedwater of model group, continuous 20 days, endoxan group injected ring phosphinylidyne daily
Amine 40mg/kg, the daily 30mL/kg gavages of Chinese medicine composition group for auxiliary treatment lung cancer, continuous 20 days.
As a result count：
Influence of 1 Chinese medicine composition of the present invention of table to lung cancer in mice weight
2 Chinese medicine composition of the present invention of table is to lung cancer in mice tumor control rate
Embodiment 4：A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer
A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer, the Chinese traditional medicine composition for auxiliary treatment lung cancer
The composition of raw materials of thing includes the material of following parts by weight：
38 parts of dendrobium candidum；
27 parts of Moschus；
30 parts of ginseng；
15 parts of cow-bezoar；
27 parts of pseudo-ginseng；
25 parts of peppermint；
21 parts of Radix Angelicae Sinensis；
22 parts of propolis；
17 parts of the tuber of dwarf lilyturf；
6 parts of borneol；
11 parts of fig；
15 parts of golden cypress；
The preparation method of the Chinese medicine composition for auxiliary treatment lung cancer comprises the following steps：
The first step：Dendrobium candidum, ginseng and pseudo-ginseng are taken, the ethanol that the volume fraction for adding 2.8 times of volumes is 65%, refluxing extraction 3
It is secondary, 3 hours every time, merge ethanol extract, the filtrate obtained after filtering is condensed into the medicinal extract that relative density is 1.27, relatively close
Spend and measured when 60 DEG C.
Second step：Moschus, cow-bezoar and peppermint are taken, adds the water of 4 times of volumes to soak 5 hours, steam distillation 5 hours, obtains
Condensate liquid and the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating.
3rd step：The dregs of a decoction obtained by second step are mixed with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and to
The decocting for wherein adding 7 times of volumes is boiled 3 times, 2 hours every time, collecting decoction, is filtered and is collected filtrate.
4th step：The aqueous solution that second step obtains is merged with the filtrate that the 3rd step is collected, is condensed into relative density as 1.4
Clear cream, relative density measures when 60 DEG C.
5th step：The clear cream that 4th step obtains is merged with the medicinal extract that the first step obtains, crushed after being dried under reduced pressure, crosses 70 mesh
Powdered extract powder is obtained after sieve.
6th step：The powdered extract powder that the volatile oil and the 5th step that magnesium stearate, second step are obtained obtain is well mixed,
Filling hard shell capsules after granulation, produce the Chinese medicine composition for auxiliary treatment lung cancer.The amount of magnesium stearate is product gross weight
3.5%。
As described above is only to explain the preferred embodiments of the invention, is not intended to tool to do any shape to the present invention
Limitation in formula, therefore all have any modification or change for making the relevant present invention under identical spirit, it should all wrap
Include the invention is intended to the category protected.
Claims (4)
- A kind of 1. preparation method of Chinese medicine composition for auxiliary treatment lung cancer, it is characterised in that：It is described to be used for auxiliary treatment The composition of raw materials of the Chinese medicine composition of lung cancer includes the material of following parts by weight：35~55 parts of dendrobium candidum；23~46 parts of Moschus；20~45 parts of ginseng；15~45 parts of cow-bezoar；13~28 parts of pseudo-ginseng；20~39 parts of peppermint；20~35 parts of Radix Angelicae Sinensis；14~28 parts of propolis；12~26 parts of the tuber of dwarf lilyturf；2~9 parts of borneol；3~11 parts of fig；10~18 parts of golden cypress；The preparation method of the Chinese medicine composition for auxiliary treatment lung cancer comprises the following steps：The first step：Dendrobium candidum, ginseng and pseudo-ginseng are taken, the ethanol that the volume fraction for adding 2~6 times of volumes is 60~75%, backflow carries Take 3~6 times, 1~3 hour every time, merge ethanol extract, the filtrate obtained after filtering be condensed into relative density for 1.15~ 1.45 medicinal extract, relative density measure when 60 DEG C；Second step：Moschus, cow-bezoar and peppermint are taken, adds the water of 3~5 times of volumes to soak 4~8 hours, steam distillation 2~6 hours, Condensate liquid and the dregs of a decoction are obtained, the condensate liquid obtains volatile oil and the aqueous solution after water-oil separating；3rd step：The dregs of a decoction obtained by second step are mixed with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and thereto The decocting for adding 6~12 times of volumes is boiled 2~4 times, 1~3 hour every time, collecting decoction, is filtered and is collected filtrate；4th step：The aqueous solution that second step obtains is merged with the filtrate that the 3rd step is collected, be condensed into relative density for 1.15~ 1.45 clear cream, relative density measure when 60 DEG C；5th step：The clear cream that 4th step obtains is merged with the medicinal extract that the first step obtains, crushed after being dried under reduced pressure, crosses 50 ~ 100 mesh Powdered extract powder is obtained after sieve；6th step：The powdered extract powder that the volatile oil and the 5th step that magnesium stearate, second step are obtained obtain is well mixed, granulation Filling hard shell capsules afterwards, produce the Chinese medicine composition for auxiliary treatment lung cancer.
- 2. the preparation method of the Chinese medicine composition according to claim 1 for auxiliary treatment lung cancer, it is characterised in that：Institute Stating includes the material of following parts by weight for the composition of raw materials of the Chinese medicine composition of auxiliary treatment lung cancer：45 parts of dendrobium candidum；38 parts of Moschus；35 parts of ginseng；36 parts of cow-bezoar；22 parts of pseudo-ginseng；32 parts of peppermint；28 parts of Radix Angelicae Sinensis；20 parts of propolis；21 parts of the tuber of dwarf lilyturf；7 parts of borneol；8 parts of fig；12 parts of golden cypress.
- 3. the preparation method of the Chinese medicine composition according to claim 1 for auxiliary treatment lung cancer, it is characterised in that：Institute It is monarch drug in a prescription to state dendrobium candidum, and Moschus, ginseng, cow-bezoar, pseudo-ginseng are ministerial drug, peppermint, Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, Golden cypress is adjuvant.
- 4. the preparation method of the Chinese medicine composition according to claim 1 for auxiliary treatment lung cancer, it is characterised in that：Institute State and comprise the following steps for the preparation method of the Chinese medicine composition of auxiliary treatment lung cancer：The first step：Dendrobium candidum, ginseng and pseudo-ginseng are taken, the ethanol that the volume fraction for adding 4 times of volumes is 70%, refluxing extraction 5 times, 2 hours every time, merge ethanol extract, the filtrate obtained after filtering is condensed into the medicinal extract that relative density is 1.35, relative density Measured when 60 DEG C；Second step：Moschus, cow-bezoar and peppermint are taken, adds the water of 4 times of volumes to soak 6 hours, steam distillation 4 hours, is condensed Liquid and the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating；3rd step：The dregs of a decoction obtained by second step are mixed with Radix Angelicae Sinensis, propolis, the tuber of dwarf lilyturf, borneol, fig, golden cypress, and thereto The decocting for adding 9 times of volumes is boiled 3 times, 2 hours every time, collecting decoction, is filtered and is collected filtrate；4th step：The aqueous solution that second step obtains is merged with the filtrate that the 3rd step is collected, be condensed into relative density be 1.3 it is clear Cream, relative density measure when 60 DEG C；5th step：The clear cream that 4th step obtains is merged with the medicinal extract that the first step obtains, crushed after being dried under reduced pressure, after crossing 80 mesh sieves Obtain powdered extract powder；6th step：The powdered extract powder that the volatile oil and the 5th step that magnesium stearate, second step are obtained obtain is well mixed, granulation Filling hard shell capsules afterwards, produce the Chinese medicine composition for auxiliary treatment lung cancer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710903675.0A CN107617056A (en) | 2017-09-29 | 2017-09-29 | A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710903675.0A CN107617056A (en) | 2017-09-29 | 2017-09-29 | A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107617056A true CN107617056A (en) | 2018-01-23 |
Family
ID=61091361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710903675.0A Pending CN107617056A (en) | 2017-09-29 | 2017-09-29 | A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107617056A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485855A (en) * | 2008-01-16 | 2009-07-22 | 北京天科仁祥医药科技有限公司 | Chinese medicine compound for treating lung cancer and manufacturing method thereof |
| CN106177497A (en) * | 2016-08-12 | 2016-12-07 | 桂林市晟博科技服务有限公司 | A kind of antitumor drug and preparation method thereof |
-
2017
- 2017-09-29 CN CN201710903675.0A patent/CN107617056A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485855A (en) * | 2008-01-16 | 2009-07-22 | 北京天科仁祥医药科技有限公司 | Chinese medicine compound for treating lung cancer and manufacturing method thereof |
| CN106177497A (en) * | 2016-08-12 | 2016-12-07 | 桂林市晟博科技服务有限公司 | A kind of antitumor drug and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102038716B (en) | Traditional Chinese medicine extraction method and special device | |
| CN104857435B (en) | A kind of Traditional Chinese medicine compound composition with antitumor activity and its preparation method and application | |
| CN102247479A (en) | Antitumor strong medicine and preparation method thereof | |
| CN102133385A (en) | Ginger and white pepper composition, preparation method thereof and application thereof to preparation of medicaments for attenuation and synergia in cancer radiochemotherapy | |
| CN103316220B (en) | A kind of active compound composition and preparation method and preparation thereof and application | |
| CN107617056A (en) | A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer | |
| CN105395600A (en) | Application of cyclocarya paliurus extract in preparing medicine for treating cardiovascular and cerebrovascular diseases | |
| CN102091312B (en) | Ginger and wild pepper composition and preparation method thereof, and application of ginger and wild pepper composition in preparation of attenuation and synergy medicaments for radiotherapy and chemotherapy of cancers | |
| CN107661445A (en) | A kind of Chinese medicine composition for auxiliary treatment lung cancer | |
| CN104288514A (en) | Traditional Chinese medicine for treating hyperthyroidism | |
| Ghavam et al. | An Overview of the Various Uses of Ephedra distachya L. from the Past to the Present | |
| CN107149653A (en) | A kind of Traditional Chinese medicine compound composition with antitumor activity and its preparation method and application | |
| CN100551410C (en) | A kind of antidepressant drug and preparation method | |
| CN105250729A (en) | Dendrobium officinale electuary and preparing method thereof | |
| CN105168582A (en) | Traditional Chinese medicine composition for children cold and preparation method thereof | |
| CN103417653A (en) | Veterinary-use compound pure Chinese herbal medicine for treating coccidium and preparation method of oral liquid of same | |
| CN103893567A (en) | Method for preparing and processing dendrobium nobile capsule | |
| CN104825784B (en) | A kind of Chinese medicine composition with anti-gastric cancer activity and its preparation method and application | |
| CN102423416B (en) | Medicament combination for preventing or treating stomach cancer | |
| CN103263492A (en) | Traditional chinese medicine extract | |
| CN101708252B (en) | Compound Chinese medicinal preparation for treating lung cancer and preparation method thereof | |
| CN102698056A (en) | Medicine for treating tinea pedis and preparation method thereof | |
| CN108634315A (en) | One kind is relieved the effect of alcohol soft capsule and preparation method thereof | |
| CN101670020A (en) | Composition for treating premenstrual syndrome | |
| CN1943608A (en) | Chinese medicine for anti-tumor and its preparing method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180123 |
|
| RJ01 | Rejection of invention patent application after publication |