CN106177497A - A kind of antitumor drug and preparation method thereof - Google Patents
A kind of antitumor drug and preparation method thereof Download PDFInfo
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- CN106177497A CN106177497A CN201610664462.2A CN201610664462A CN106177497A CN 106177497 A CN106177497 A CN 106177497A CN 201610664462 A CN201610664462 A CN 201610664462A CN 106177497 A CN106177497 A CN 106177497A
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- powder
- weight portion
- radix ginseng
- antitumor drug
- dendrobe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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Abstract
The present invention relates to a kind of antitumor drug and preparation method thereof.A kind of antitumor drug, including following parts by weight of component: betulinol 0.1 0.3 weight portion, Herba Dendrobii 20 30 weight portion and Radix Ginseng 5 10 weight portion.A kind of antitumor drug preparation method, comprises the following steps: dendrobe powder is broken into powder, obtains dendrobe powder；Radix Ginseng powder is broken into powder, obtains Radix Ginseng powder；Weigh betulinol 0.1 0.3 weight portion, dendrobe powder 20 30 weight portion and Radix Ginseng powder 5 10 weight portion, mix together, prepare antitumor drug.Antitumor drug of the present invention and preparation method thereof has that therapeutic effect is good, instant effect and the advantage such as preparation method is simple.
Description
Technical field
The invention belongs to biomedicine field, particularly relate to a kind of antitumor drug and preparation method thereof.
Background technology
Tumor is a kind of frequently-occurring disease, is one of the most serious disease endangering human health.Not yet have for tumor at present
Cell can have the medicine for the treatment of very well.
Current quality tumour medicine is primarily present problems with, such as: therapeutic effect is poor, take effect slow, and side effect is big.
Therefore, develop that a to have oncotherapy medicine effective, instant effect significant.
Summary of the invention
In view of the problem existing for prior art, the present invention provides a kind of antitumor drug and preparation method thereof, has and controls
The advantages such as therapeutic effect is good, instant effect and preparation method are simple.
The technical scheme is that
A kind of antitumor drug, including following parts by weight of component: betulinol 0.1-0.3 weight portion, Herba Dendrobii 20-30 weight portion
With Radix Ginseng 5-10 weight portion.
The invention has the beneficial effects as follows: the present invention, by reasonably arranging each component and proportioning, has treatment tumor effect
The best, instant effect and the advantage such as preparation method is simple.
On the basis of technique scheme, the present invention can also do following improvement.
Further, including following parts by weight of component: betulinol 0.2 weight portion, Herba Dendrobii 25 weight portion and Radix Ginseng 7 weight portion.
Above-mentioned further scheme is used to provide the benefit that: oncotherapy effect can be improved further.
The present invention also provides for a kind of antitumor drug preparation method, comprises the following steps:
1) dendrobe powder is broken into powder, obtains dendrobe powder；
2) Radix Ginseng powder is broken into powder, obtains Radix Ginseng powder；
3) weigh betulinol 0.1-0.3 weight portion, dendrobe powder 20-30 weight portion and Radix Ginseng powder's 5-10 weight portion, mix together
Even, prepare antitumor drug.
The invention has the beneficial effects as follows: preparation method of the present invention has simple operation and other advantages, prepared is anti-swollen
Tumor requires to have treatment, and tumor effect is good, instant effect and the advantage such as preparation method is simple.
Further, the particle diameter of described dendrobe powder is 10-50 micron.
Further, the particle diameter of described Radix Ginseng powder is 10-50 micron.
Use such scheme to provide the benefit that: the particle diameter of dendrobe powder and Radix Ginseng powder is 10-50 micron, be conducive to absorbing,
Improve drug effect.
Further, step 3) in, weigh betulinol 0.2 weight portion, dendrobe powder 25 weight portion and Radix Ginseng powder 7 weight portion, one
Play mixing, prepare antitumor drug.
Above-mentioned further scheme is used to provide the benefit that: oncotherapy effect can be improved further.
Detailed description of the invention
Principle and feature to the present invention are described below, and example is served only for explaining the present invention, is not intended to limit
Determine the scope of the present invention.
A kind of antitumor drug preparation method, comprises the following steps:
1) dendrobe powder being broken into powder, the particle diameter of described dendrobe powder is 10-50 micron, obtains dendrobe powder；
2) Radix Ginseng powder being broken into powder, the particle diameter of described Radix Ginseng powder is 10-50 micron, obtains Radix Ginseng powder；
3) weigh betulinol 0.1-0.3 weight portion, dendrobe powder 20-30 weight portion and Radix Ginseng powder's 5-10 weight portion, mix together
Even, prepare antitumor drug.
Introduce below by specific embodiment.
Embodiment 1
A kind of antitumor drug preparation method, comprises the following steps:
1) dendrobe powder being broken into powder, the particle diameter of described dendrobe powder is 25 microns, obtains dendrobe powder；
2) Radix Ginseng powder being broken into powder, the particle diameter of described Radix Ginseng powder is 25 microns, obtains Radix Ginseng powder；
3) weigh betulinol 0.2 kilogram, dendrobe powder 25 kilograms and Radix Ginseng powder 7 kilograms, mix together, prepare antineoplastic agent
Thing.
Embodiment 2
A kind of antitumor drug preparation method, comprises the following steps:
1) dendrobe powder being broken into powder, the particle diameter of described dendrobe powder is 10 microns, obtains dendrobe powder；
2) Radix Ginseng powder being broken into powder, the particle diameter of described Radix Ginseng powder is 10 microns, obtains Radix Ginseng powder；
3) weigh betulinol 0.1 kilogram, dendrobe powder 20 kilograms and Radix Ginseng powder 5 kilograms, mix together, prepare antineoplastic agent
Thing.
Embodiment 3
A kind of antitumor drug preparation method, comprises the following steps:
1) dendrobe powder being broken into powder, the particle diameter of described dendrobe powder is 50 microns, obtains dendrobe powder；
2) Radix Ginseng powder being broken into powder, the particle diameter of described Radix Ginseng powder is 50 microns, obtains Radix Ginseng powder；
3) weigh betulinol 0.3 kilogram, dendrobe powder 30 kilograms and Radix Ginseng powder 10 kilograms, mix together, prepare antineoplastic agent
Thing.
Comparative example 1
Being substituted by the starch of betulinol equivalent, remaining is the most same as in Example 1.
Comparative example 2
Being substituted by the starch of dendrobe powder equivalent, remaining is the most same as in Example 1.
Comparative example 3
Being substituted by the starch of Radix Ginseng powder's equivalent, remaining is the most same as in Example 1.
Measure of merit
Embodiment 1-embodiment 3 and comparative example 1-comparative example 3 are carried out antitumous effect confirmatory experiment respectively.
Specific experiment method reference literature: Wei Haiqing, Li Junxia, Wang Yongli, the research of inulin extracorporeal anti-tumor function,
Hebei medicine, the 13rd phase of volume 33 in July, 2011,1938-1940 page.
With murine hepatocarcinoma cell 1122 cell and Mouse sarcoma S180 cells as object of study.Middle high low dosage is respectively as follows:
Low dosage 2mg/L, middle dosage is 8mg/L, and high dose is 20mg/L.Testing result is carried out statistical analysis and calculating is the most right
Murine hepatocarcinoma cell 1122 cell and the suppression ratio of Mouse sarcoma S180 cells.Experimental result is shown in Table 1.
Table 1
According to the data in table 1 it can be seen that embodiment 1-embodiment 3 to be had the effect well treating tumor.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Within principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (6)
1. an antitumor drug, it is characterised in that include following parts by weight of component: betulinol 0.1-0.3 weight portion, Herba Dendrobii
20-30 weight portion and Radix Ginseng 5-10 weight portion.
A kind of antitumor drug, it is characterised in that include following parts by weight of component: betulinol 0.2
Weight portion, Herba Dendrobii 25 weight portion and Radix Ginseng 7 weight portion.
3. an antitumor drug preparation method, it is characterised in that comprise the following steps:
1) dendrobe powder is broken into powder, obtains dendrobe powder；
2) Radix Ginseng powder is broken into powder, obtains Radix Ginseng powder；
3) weigh betulinol 0.1-0.3 weight portion, dendrobe powder 20-30 weight portion and Radix Ginseng powder's 5-10 weight portion, mix together, system
Obtain antitumor drug.
A kind of antitumor drug preparation method, it is characterised in that the particle diameter of described dendrobe powder is
10-50 micron.
A kind of antitumor drug preparation method, it is characterised in that the particle diameter of described Radix Ginseng powder is
10-50 micron.
6. according to antitumor drug preparation method a kind of described in any one of claim 3-5, it is characterised in that step 3) in, claim
Take betulinol 0.2 weight portion, dendrobe powder 25 weight portion and Radix Ginseng powder 7 weight portion, mix together, prepare antitumor drug.
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| CN201610664462.2A CN106177497A (en) | 2016-08-12 | 2016-08-12 | A kind of antitumor drug and preparation method thereof |
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| CN201610664462.2A CN106177497A (en) | 2016-08-12 | 2016-08-12 | A kind of antitumor drug and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107617056A (en) * | 2017-09-29 | 2018-01-23 | 南京仙草堂生物科技有限公司 | A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer |
| CN107661445A (en) * | 2017-09-29 | 2018-02-06 | 南京仙草堂生物科技有限公司 | A kind of Chinese medicine composition for auxiliary treatment lung cancer |
| CN109010618A (en) * | 2018-09-21 | 2018-12-18 | 珠海霍普金斯医药研究院股份有限公司 | A kind of Chinese medicine composition and preparation method and application with antitumor action |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101658638A (en) * | 2009-09-17 | 2010-03-03 | 晏兰芬 | Dendrobium wine and preparation method thereof |
-
2016
- 2016-08-12 CN CN201610664462.2A patent/CN106177497A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101658638A (en) * | 2009-09-17 | 2010-03-03 | 晏兰芬 | Dendrobium wine and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 任泽明，等: "铁皮石斛洋参浸膏对肿瘤生长及荷瘤小鼠免疫功能影响的实验研究", 《浙江中医杂志》 * |
| 刘建林，等: "几种人参属中药提取物的制备及体外抗卵巢癌活性比较", 《中国实验方剂学杂志》 * |
| 刘晓康，等: "桦木醇对人结肠癌ＳＷ４８０细胞增殖和凋亡的影响", 《吉林大学学报（医学版）》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107617056A (en) * | 2017-09-29 | 2018-01-23 | 南京仙草堂生物科技有限公司 | A kind of preparation method of Chinese medicine composition for auxiliary treatment lung cancer |
| CN107661445A (en) * | 2017-09-29 | 2018-02-06 | 南京仙草堂生物科技有限公司 | A kind of Chinese medicine composition for auxiliary treatment lung cancer |
| CN109010618A (en) * | 2018-09-21 | 2018-12-18 | 珠海霍普金斯医药研究院股份有限公司 | A kind of Chinese medicine composition and preparation method and application with antitumor action |
| CN109010618B (en) * | 2018-09-21 | 2022-01-21 | 珠海霍普金斯医药研究院股份有限公司 | Traditional Chinese medicine composition with anti-tumor effect and preparation method and application thereof |
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Application publication date: 20161207 |
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