CN107517998A - A kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle - Google Patents
A kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle Download PDFInfo
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- CN107517998A CN107517998A CN201610452897.0A CN201610452897A CN107517998A CN 107517998 A CN107517998 A CN 107517998A CN 201610452897 A CN201610452897 A CN 201610452897A CN 107517998 A CN107517998 A CN 107517998A
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- China
- Prior art keywords
- quaternary ammonium
- ammonium salt
- preparation
- salt modification
- copper
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
- A01N55/02—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
Abstract
This application discloses a kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle, including step：(1), alkyldimethylbenzylammonium chloride is dissolved in water, is uniformly mixed；(2) mixed solution, is warming up to 40~50 DEG C, N is added under stirring2H4·H2O, continue to be stirred；(3) copper sulfate solution, is continuously added, adjusts pH to 5~6, reacts certain time；(4), centrifugation, supersound washing and drying, the Nanometer Copper antibacterial granule of quaternary ammonium salt modification is obtained.Nano-antibacterial particle of the present invention is in regular spherical, uniform particle diameter and good dispersion.Nano-antibacterial particle of the present invention has good bactericidal property to Escherichia coli and staphylococcus aureus.
Description
Technical field
The application is related to a kind of nano anti-biotic material, and the system of copper nano-antibacterial particle is modified more particularly to a kind of quaternary ammonium salt
Preparation Method.
Background technology
Nano anti-biotic material generally has broad-spectrum antiseptic, is not likely to produce the characteristics of drug-fast bacteria, can be widely used in
The numerous areas such as plastics, textile, coating, household electrical appliance.
Copper nano material due to special physics and chemical property, lubricating additive, anti-biotic material, sensor,
Effective catalyst etc. is widely used.
Quaternary ammonium disinfectant is low effect disinfectants in one kind, and this kind of disinfectant belongs to cationic surfactant, wherein
Nitrogen-atoms and four alkyl be connected to form the group of a positively charged, and negatively charged part is usually chlorion or bromide ion,
This kind of cationic surfactant, which is widely used, does the coating material of preparation nano material.
The content of the invention
It is existing to overcome it is an object of the invention to provide a kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle
Deficiency in technology.
To achieve the above object, the present invention provides following technical scheme：
The embodiment of the present application discloses a kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle, including step：
(1), alkyldimethylbenzylammonium chloride is dissolved in water, is uniformly mixed；
(2) mixed solution, is warming up to 40~50 DEG C, N is added under stirring2H4·H2O, continue to be stirred；
(3) copper sulfate solution, is continuously added, adjusts pH to 5~6, reacts certain time；
(4), centrifugation, supersound washing and drying, the Nanometer Copper antibacterial granule of quaternary ammonium salt modification is obtained.
Preferably, in the preparation method of above-mentioned quaternary ammonium salt modification copper nano-antibacterial particle, in step (3), copper sulphate
Concentration of aqueous solution is 0.045~0.7mol/L.
Preferably, in the preparation method of above-mentioned quaternary ammonium salt modification copper nano-antibacterial particle, in step (3), using hydrogen
Sodium hydroxide solution adjusts pH to 5~6.
Preferably, in the preparation method of above-mentioned quaternary ammonium salt modification copper nano-antibacterial particle, in step (3), during reaction
Between be 30~60min.
Preferably, in the preparation method of above-mentioned quaternary ammonium salt modification copper nano-antibacterial particle, the copper sulphate and N2H4·
H2O mol ratio is 1:(2~3).
Preferably, in the preparation method of above-mentioned quaternary ammonium salt modification copper nano-antibacterial particle, the copper sulphate and algae is killed
The mol ratio of amine is 1：(7~9).
Compared with prior art, the advantage of the invention is that：Nano-antibacterial particle of the present invention is spherical in rule, and particle diameter is equal
One and good dispersion.Nano-antibacterial particle of the present invention has good bactericidal property to Escherichia coli and staphylococcus aureus.
Embodiment
The present invention is described further by the following example：According to following embodiments, the present invention may be better understood.
However, as it will be easily appreciated by one skilled in the art that specific material ratio, process conditions and its result described by embodiment are only used
In the explanation present invention, without should be also without limitation on the present invention described in detail in claims.
Embodiment 1
Quaternary ammonium salt modifies the preparation method of copper nano-antibacterial particle
(1), alkyldimethylbenzylammonium chloride is dissolved in water, is uniformly mixed；
(2) mixed solution, is warming up to 50 DEG C, N is added under stirring2H4·H2O, continue to be stirred；
(3) 0.045mol/L copper sulfate solution, is continuously added, pH to 5, reaction are adjusted using sodium hydroxide solution
30min。
Copper sulphate and N2H4·H2O mol ratio is 1:2；
The mol ratio of copper sulphate and alkyldimethylbenzylammonium chloride is 1：7.3.
(4), centrifugation, supersound washing and drying, the Nanometer Copper antibacterial granule of quaternary ammonium salt modification is obtained.
Product is characterized using the methods of SEM, TEM, XRD, for the nano particle of acquisition in the spherical of rule, particle diameter is equal
One and good dispersion.
The product obtained has good bactericidal property to Escherichia coli and staphylococcus aureus.
Embodiment 2
Quaternary ammonium salt modifies the preparation method of copper nano-antibacterial particle
(1), alkyldimethylbenzylammonium chloride is dissolved in water, is uniformly mixed；
(2) mixed solution, is warming up to 50 DEG C, N is added under stirring2H4·H2O, continue to be stirred；
(3) 0.045mol/L copper sulfate solution, is continuously added, pH to 6, reaction are adjusted using sodium hydroxide solution
40min。
Copper sulphate and N2H4·H2O mol ratio is 1:3；
The mol ratio of copper sulphate and alkyldimethylbenzylammonium chloride is 1：9.
(4), centrifugation, supersound washing and drying, the Nanometer Copper antibacterial granule of quaternary ammonium salt modification is obtained.
Product is characterized using the methods of SEM, TEM, XRD, for the nano particle of acquisition in the spherical of rule, particle diameter is equal
One and good dispersion.
Finally, it is to be noted that, term " comprising ", "comprising" or its any other variant be intended to it is non-exclusive
Property includes, so that process, method, article or equipment including a series of elements not only include those key elements, and
Also include the other element that is not expressly set out, or also include for this process, method, article or equipment inherently
Key element.
Claims (6)
1. a kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle, it is characterised in that including step：
(1), alkyldimethylbenzylammonium chloride is dissolved in water, is uniformly mixed；
(2) mixed solution, is warming up to 40~50 DEG C, N is added under stirring2H4·H2O, continue to be stirred；
(3) copper sulfate solution, is continuously added, adjusts pH to 5~6, reacts certain time；
(4), centrifugation, supersound washing and drying, the Nanometer Copper antibacterial granule of quaternary ammonium salt modification is obtained.
2. the preparation method of quaternary ammonium salt modification copper nano-antibacterial particle according to claim 1, it is characterised in that：Step
(3) in, copper sulfate solution concentration is 0.045~0.7mol/L.
3. the preparation method of quaternary ammonium salt modification copper nano-antibacterial particle according to claim 1, it is characterised in that：Step
(3) in, pH to 5~6 is adjusted using sodium hydroxide solution.
4. the preparation method of quaternary ammonium salt modification copper nano-antibacterial particle according to claim 1, it is characterised in that：Step
(3) in, the reaction time is 30~60min.
5. the preparation method of quaternary ammonium salt modification copper nano-antibacterial particle according to claim 1, it is characterised in that：The sulphur
Sour copper and N2H4·H2O mol ratio is 1:(2~3).
6. the preparation method of quaternary ammonium salt modification copper nano-antibacterial particle according to claim 1, it is characterised in that：The sulphur
The mol ratio of sour copper and alkyldimethylbenzylammonium chloride is 1：(7~9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610452897.0A CN107517998A (en) | 2016-06-22 | 2016-06-22 | A kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610452897.0A CN107517998A (en) | 2016-06-22 | 2016-06-22 | A kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107517998A true CN107517998A (en) | 2017-12-29 |
Family
ID=60735187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610452897.0A Withdrawn CN107517998A (en) | 2016-06-22 | 2016-06-22 | A kind of preparation method of quaternary ammonium salt modification copper nano-antibacterial particle |
Country Status (1)
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112294895A (en) * | 2020-08-24 | 2021-02-02 | 福州弘海生物科技有限公司 | Male delayed spray and preparation method thereof |
-
2016
- 2016-06-22 CN CN201610452897.0A patent/CN107517998A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 张文凤: "铜纳米材料的制备及抗菌性能研究", 《中国优秀硕士学位论文全文数据库 工程科技Ⅰ辑》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112294895A (en) * | 2020-08-24 | 2021-02-02 | 福州弘海生物科技有限公司 | Male delayed spray and preparation method thereof |
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20171229 |
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| WW01 | Invention patent application withdrawn after publication |