CN102986669A - Stable bactericide composition - Google Patents
Stable bactericide composition Download PDFInfo
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- CN102986669A CN102986669A CN2012105893653A CN201210589365A CN102986669A CN 102986669 A CN102986669 A CN 102986669A CN 2012105893653 A CN2012105893653 A CN 2012105893653A CN 201210589365 A CN201210589365 A CN 201210589365A CN 102986669 A CN102986669 A CN 102986669A
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Abstract
The invention relates to a stable bactericide composition, which contains 1,2-benzisothiazolin-3-one and 2-methyl-4-isothiazolizone-3-one, wherein the proportion by weight of 1,2-benzisothiazolin-3-one to 2-methyl-4-isothiazolizone-3-one is 1-5: 5-1. The composition further contains a solvent; and 1,2-benzisothiazolin-3-one and 2-methyl-4-isothiazolizone-3-one account for 20-30% of the composition according to percentage by weight. The stable bactericide composition provided by the invention has excellent stability, and the experimental result shows that the bactericide composition does not produce precipitates in 30 days at a temperature of 60 DEG C; the bactericide composition does not contain a bivalent metal salt, can be used in water paint such as emulsion paint stably, and can effectively inhibit the growth of harmful microorganisms.
Description
Technical field
The present invention relates to the bactericide technical field, be specifically related to a kind of stable microbicide compositions.
Background technology
Preservation in order to ensure product and material, control or prevent microbial growth, the fields such as bactericide is widely used in Treatment of Industrial Water, industrial oil additive, building materials are anticorrosion, electric power is metallurgical, oilfield chemical, leather, paint, coating, weaving, printing and dyeing, daily use chemicals, cosmetics, papermaking, emulsion, for example, be used for controlling harmful bacterium, fungi, mould and algae, the composition that bactericide in most of the cases uses the active substance by several bactericide to form.
By 1, the microbicide compositions that 2-benzisothiazole-3-ketone and MIT form has very widely application as antibacterium and antifungus active substance, for example at water paint (emulsion paint), in the aqueous products such as polymer emulsion, adhesive, filler, fluid sealant, can avoid harmful microorganism pollutes, especially be fit to the higher product of pH value, such as water paint (emulsion paint) etc.
Chinese patent ZL98808300.0 has described a kind of bacteriocide formula, is comprised of BIT and MIT, and the total concentration of BIT and MIT is 1-20%.The pH value of the said composition aqueous solution is defined as 7-9, and low pH value scope like this is so that the scope of application of said composition (for example pH=9.0-10) is restricted.Thereby the stability of composition under alkali condition of this BIT and MIT composition is affected.
Summary of the invention
Limitation for prior art, we have invented a kind of adaptation in high pH value scope, particularly at that use, that in water paint, use, the stable and reliable for performance alkaline bacteriocide formula that is formed by BIT and MIT of alkaline range.
Stable microbicide compositions comprises BIT and MIT, and the weight ratio of described BIT and MIT is 1:1.
Described composition also comprises solvent, and the percentage by weight that described BIT and MIT account for described composition is 20～30%.
Described solvent is selected from least a in water, propane diols, ethylene glycol or the dipropylene glycol, is preferably water.
Described when making solvent with water, the pH value of microbicide compositions is adjusted to 9～10.
Described composition also comprises neutralizer, and the percentage by weight that described neutralizer accounts for described composition is 2.5～6.0%.
Described neutralizer is selected from least a in sodium hydroxide, the potassium hydroxide.
Described stabilizing agent is selected from least a in oxidant, the amino carboxylic acid salt compound.
The percentage by weight that described oxidant accounts for described composition is 0.005～1.0%, and the percentage by weight that described aminocarboxylate accounts for described composition is 0.0005～0.01%.
Described oxidant is sodium peroxide, sodium chlorite, at least a in potassium bromate, Potassiumiodate, the sodium metaperiodate.
Described aminocarboxylate is selected from least a in nitrilotriacetic acid sodium, the edetate (EDETATE SODIUM or four sodium).
The invention has the beneficial effects as follows:
The microbicide compositions that the present invention is stable has relatively high activity concentration (20-30%), has advantages of the packing of saving and freight, adds simultaneously a certain amount of stabilizing agent, so that microbicide compositions can for a long time stable storage.
The microbicide compositions that the present invention is stable has excellent stability, and experimental result is given under 60 ℃ the temperature condition, deposit 30 days precipitation form; Do not contain divalent metal salt in the composition, stable being used in the water paint (emulsion paint) of energy effectively suppresses the harmful microbe growth.
Embodiment
Embodiment 1
| Component | Content (percentage by weight) |
| BIT | 10.0% |
| MIT | 10.0% |
| Sodium hydroxide | 2.65% |
| Sodium chlorite | 0.02% |
| EDETATE SODIUM | 0.002% |
| Water | 77.328% |
Embodiment 2
| Component | Content (percentage by weight) |
| BIT | 12.5% |
| MIT | 12.5% |
| Sodium hydroxide | 3.31% |
| Potassium bromate | 0.005% |
| Nitrilotriacetic acid sodium | 0.01% |
| Water | 71.675% |
Embodiment 3
| Component | Content (percentage by weight) |
| BIT | 15.0% |
| MIT | 15.0% |
| Potassium hydroxide | 5.56% |
| Potassiumiodate | 0.005% |
| EDTA four sodium | 0.002% |
| Water | 64.433% |
Embodiment 4
| Component | Content (percentage by weight) |
| BIT | 12.5% |
| MIT | 12.5% |
| Potassium hydroxide | 4.63% |
| Sodium peroxide | 0.005% |
| EDETATE SODIUM | 0.001% |
| Water | 70.364% |
Component of the present invention and content are not limited to above-described embodiment.
Preparation contains 1, the technical process of the bactericidal composition of 2-benzisothiazole-3-ketone and MIT is: with 1, the 2-benzisothiazole-3-ketone is suspended in the aqueous solution, with the alkali metal hydroxide pH=9.0-10.0 that neutralizes, the aqueous solution that obtains clarifying, then add stabilizing agent and MIT, the microbicide compositions product stirs to get.
With the sample of embodiment 1-4 configuration 60 ℃ place 30 fates after, analyze main active ingredient BIT (BIT) with high performance liquid chromatography (HPLC), the content of 2-methyl-3-isothiazoline-3-ketone (MIT) the results are shown in following table.
As can be seen from the above table, the sample that adds the stabilizing agent of proper proportion, place 30 days active ingredient change in concentration at 60 ℃ very little, the present invention relates to contain BIT and the MIT composition has obvious stablizing effect.
The above; only be the better embodiment of the present invention; but protection scope of the present invention is not limited to this; anyly be familiar with those skilled in the art in the technical scope that the present invention discloses; be equal to replacement or change according to technical scheme of the present invention and inventive concept thereof, all should be encompassed within protection scope of the present invention.
Claims (10)
1. stable microbicide compositions is characterized in that, comprises BIT and MIT, and the weight ratio of described BIT and MIT is 1～5:5～1.
2. stable microbicide compositions according to claim 1 is characterized in that, described composition also comprises solvent, and the percentage by weight that described BIT and MIT account for described composition is 20～30%.
3. stable microbicide compositions according to claim 2 is characterized in that, described solvent is selected from least a in water, propane diols, ethylene glycol or the dipropylene glycol.
4. stable microbicide compositions according to claim 3 is characterized in that, described when making solvent with water, the pH value of microbicide compositions is adjusted to 9～10.
5. the described stable microbicide compositions of any one is characterized in that according to claim 1-4, and described composition also comprises neutralizer, and the percentage by weight that described neutralizer accounts for described composition is 2.5～6.0%.
6. stable microbicide compositions according to claim 5 is characterized in that, described neutralizer is selected from least a in sodium hydroxide, the potassium hydroxide.
7. stable microbicide compositions according to claim 5 is characterized in that, described composition also comprises stabilizing agent, and described stabilizing agent is selected from least a in oxidant, the amino carboxylic acid salt compound.
8. stable microbicide compositions according to claim 7 is characterized in that, the percentage by weight that described oxidant accounts for described composition is 0.005～1.0%, and the percentage by weight that described aminocarboxylate accounts for described composition is 0.0005～0.01%.
9. according to claim 7 or 8 described stable microbicide compositions, it is characterized in that, described oxidant is sodium peroxide, sodium chlorite, at least a in potassium bromate, Potassiumiodate, the sodium metaperiodate.
10. according to claim 7 or 8 described stable microbicide compositions, it is characterized in that, described aminocarboxylate is selected from least a in nitrilotriacetic acid sodium, the edetate (EDETATE SODIUM or four sodium).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105893653A CN102986669A (en) | 2012-12-31 | 2012-12-31 | Stable bactericide composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105893653A CN102986669A (en) | 2012-12-31 | 2012-12-31 | Stable bactericide composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102986669A true CN102986669A (en) | 2013-03-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012105893653A Pending CN102986669A (en) | 2012-12-31 | 2012-12-31 | Stable bactericide composition |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105165846A (en) * | 2015-09-17 | 2015-12-23 | 上海万厚生物科技有限公司 | BBIT water emulsion and preparation method thereof |
| CN108308194A (en) * | 2018-04-20 | 2018-07-24 | 东莞市顶盛环保科技有限公司 | A kind of composite multifunction fungicide |
| CN111087653A (en) * | 2019-11-13 | 2020-05-01 | 嘉兴学院 | Preservative for waterborne polyurethane emulsion and preparation method thereof |
| CN113243381A (en) * | 2021-05-31 | 2021-08-13 | 浙江先拓环保科技有限公司 | Composite mildew-proof antibacterial agent and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1267192A (en) * | 1997-08-20 | 2000-09-20 | 托尔化学有限公司 | Synergistic biocide composition |
| CN102510722A (en) * | 2009-10-02 | 2012-06-20 | 乔治洛德方法研究和开发液化空气有限公司 | Antimicrobially effective use solutions comprising combinations of isothiazolones and amines |
| CN102573495A (en) * | 2009-10-02 | 2012-07-11 | 乔治洛德方法研究和开发液化空气有限公司 | Storage-stable, synergistic microbicidal concentrates containing an isothiazolone, an amine and an oxidizing agent |
-
2012
- 2012-12-31 CN CN2012105893653A patent/CN102986669A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1267192A (en) * | 1997-08-20 | 2000-09-20 | 托尔化学有限公司 | Synergistic biocide composition |
| CN102510722A (en) * | 2009-10-02 | 2012-06-20 | 乔治洛德方法研究和开发液化空气有限公司 | Antimicrobially effective use solutions comprising combinations of isothiazolones and amines |
| CN102573495A (en) * | 2009-10-02 | 2012-07-11 | 乔治洛德方法研究和开发液化空气有限公司 | Storage-stable, synergistic microbicidal concentrates containing an isothiazolone, an amine and an oxidizing agent |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105165846A (en) * | 2015-09-17 | 2015-12-23 | 上海万厚生物科技有限公司 | BBIT water emulsion and preparation method thereof |
| CN108308194A (en) * | 2018-04-20 | 2018-07-24 | 东莞市顶盛环保科技有限公司 | A kind of composite multifunction fungicide |
| CN111087653A (en) * | 2019-11-13 | 2020-05-01 | 嘉兴学院 | Preservative for waterborne polyurethane emulsion and preparation method thereof |
| CN113243381A (en) * | 2021-05-31 | 2021-08-13 | 浙江先拓环保科技有限公司 | Composite mildew-proof antibacterial agent and preparation method thereof |
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Application publication date: 20130327 |