CN107451687A - A kind of method tested running stores and be automatically replenished stock - Google Patents
A kind of method tested running stores and be automatically replenished stock Download PDFInfo
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Abstract
The running stores method that is automatically replenished stock is tested the invention provides a kind of, for research center, including：Obtain a kind of current stock E for testing running stores and the historical data using the experiment running stores in research center；According to default predetermined period T that replenishes the stock, the estimated total number of persons L that comes off in predetermined period T that replenishes the stock is calculated；Interview number S of the enrolled subject in predetermined period of replenishing the stock, i.e., interview number U and use experiment running stores total amount R by enrolled subject in predetermined period of replenishing the stock are calculated using experiment running stores quantity N, P weeks interview cycle of subject according to default subject per's interview；The complementary testing running stores quantity Q of the predetermined period of replenishing the stock is calculated, the request replenished the stock then is sent to warehouse；To research center complementary testing running stores, the present invention is capable of the stock of adaptive complementary testing running stores in warehouse, stock's abundance of automatic guarantee test running stores but does not waste.
Description
Technical field
The present invention relates to stock managing and controlling field, specifically, is related to a kind of method tested running stores and be automatically replenished stock.
Background technology
Clinical drug research is a kind of experiment using huge therapeutic amount, and each medicament will be transported from warehouse
Each research center or hospital are sent to, is then sent to subject from research center again, then used.
Due to clinical research experiment running stores (including medicine or hospital gauze, syringe, artificial cornea etc. examination
Test and use apparatus) it is extremely expensive, transport and the condition preserved are all very harsh, and medicine experiment integral cycle is very long, subject
Number is more, different tests running stores require that the interview cycle of subject is also different, and number of subjects can send out according to different situations
Changing, it is difficult to predict the quantity of complementary testing running stores.Such as：Hospital orders more, then cost is too high, and also to face to protect
The problem of depositing medicine；Order less, be then difficult to the requirement of experiment, if experiment, once should be medicine deficiency and interrupt, just having can
Last result of the test can be influenceed, or even entirely medicine experiment must all be reformed, serious economic loss can be caused.
In addition, distance is indefinite between different warehouses and hospital, traffic condition is different, supplement of the warehouse to each hospital is caused
The haul-cycle time of experiment running stores also has nothing in common with each other, so, warehouse also is difficult to determine that suitable complementary testing disappears to each hospital
The quantity of consumption product.
Therefore, hospital or warehouse are all in the side for seeking a kind of a kind of experiment running stores that can be adaptive and being automatically replenished stock
Method.
The content of the invention
For the problems of the prior art, it is an object of the invention to provide a kind of experiment running stores to be automatically replenished stock's
Method, overcome the difficulty of prior art, can be consumed according to predetermined period of replenishing the stock, the adaptive complementary testing of number of subjects
The stock of product, the stock of automatic guarantee test running stores is sufficient but does not waste.
Embodiments of the invention provide a kind of method tested running stores and be automatically replenished stock, for research center, including
Following steps：
Step S101, obtain a kind of current stock E for testing running stores in research center and use the experiment running stores
Historical data, the historical data includes average carrying out screening number A, history screening failure total number of persons B, history weekly and coming off
Total number of persons C and history screen successfully total number of persons D, wherein, A, B, C, D, E are constant；
Step S102, according to default predetermined period T that replenishes the stock, calculate estimated de- in predetermined period T that replenishes the stock
Fall total number of persons L, wherein, T, L are constant；
Step S103, experiment running stores quantity N, P weeks interview cycle of subject are used according to default subject per's interview
Calculate interview number S of the enrolled subject in predetermined period of replenishing the stock, enrolled subject is predicted replenishing the stock
Interview number U and use experiment running stores total amount R in cycle, are calculated using experiment running stores total amount using below equation
R, wherein, N, S, U, R are constant,
R=[S+U-L × (T ÷ P)] × N；
Step S104, the complementary testing running stores quantity Q of the predetermined period of replenishing the stock is calculated using below equation, so
The request replenished the stock is sent to warehouse afterwards, Q is constant,
Q=R+ (V-E)；
Wherein, V is the safety inventory in default research center, and V is constant；Safety inventory V in the present invention can be base
Calculated in past history；The value that research center staff sets according to actual conditions can also be responsible for, is not limited.
Step S105, warehouse is mended according to the complementary testing running stores quantity Q of the predetermined period of replenishing the stock to research center
Fill experiment running stores.
Experiment running stores in the present invention can include a kind of medicine or a kind of hospital gauze, a kind of syringe, artificial
Experiment apparatus such as cornea etc., but be not limited.
Research center in the present invention can be have medicine experiment qualification hospital or pharmaceutical research unit, but not with
This is limited.
Preferably, comprise the following steps in the step S102：
Step S1021, subject screening failure rate F is calculated,
F=B ÷ (B+D)；
Step S1022, estimated screening failure total number of persons H is calculated,
H=F × (A × T+B+D)；
Step S1023, it is constant to calculate screening failure the number J, J to replenish the stock in predetermined period,
J=H-B；
Step S1024, it is constant to calculate enter weekly group the number G, G to replenish the stock in predetermined period,
G=A-J ÷ T；
Step S1025, subject expulsion rate W is calculated,
W=C ÷ D；
Step S1026, it is constant to calculate estimated come off total number of persons K, K,
K=W × (A × T+B+D-H)；
Step S1027, the estimated number L that comes off in predetermined period of replenishing the stock is calculated,
L=K-C.
Preferably, comprise the following steps in the step S103：
Step S1031, interview number S of the enrolled subject in predetermined period of replenishing the stock is calculated,
S=(D-C) × (T ÷ P)；
Step S1032, the interview number U i.e. by enrolled subject in predetermined period of replenishing the stock is calculated,
U=[G × T × (T ÷ P+1)] ÷ 2；
Step S1033, calculate using experiment running stores total amount R,
R=[S+U-L × (T ÷ P)] × N.
Preferably, step S1032, round is carried out to interview number U or rounded by entering a method.
Preferably, in the step S102, step S1025 can be arranged in before the step S1021.
Preferably, in the step S103, step S1031 can exchange with step S1032 order.
Preferably, in the step S104, it is normal that Z, which is equal to experiment running stores to transport to research center required cycle, Z,
Number；The safety inventory V in research center is calculated using below equation,
V=A × (N ÷ P) × Z.
Preferably, the safety inventory V in the research center is equal to the history of the experiment running stores averagely weekly using experiment
Running stores total amount is multiplied by the cycle that experiment running stores are transported to research center needs.
Preferably, the step S105 is replaced with according to predetermined period T weeks of replenishing the stock, the regular transport test every T weeks
Running stores are to warehouse.
Preferably, also include before the step S101：
Step S100, whether a kind of current stock E for testing running stores is more than or equal in research center described in real-time judge
The safety inventory V in default research center, if it is not, then performing step S101.
Preferably, the step S105 replaces with warehouse transport test running stores is replenished the stock at once.
The method that a kind of experiment running stores of the present invention are automatically replenished stock can be according to predetermined period of replenishing the stock, tested
The stock of the adaptive complementary testing running stores of person's number, the stock of automatic guarantee test running stores is sufficient but does not waste.
Brief description of the drawings
The detailed description made by reading with reference to the following drawings to non-limiting example, further feature of the invention,
Objects and advantages will become more apparent upon.
Fig. 1 is the implementation schematic diagram that a kind of experiment running stores of the present invention are automatically replenished the method for stock；
Fig. 2 is the flow chart that a kind of experiment running stores of the present invention are automatically replenished the method for stock；
Fig. 3 is that a kind of experiment running stores of the present invention are automatically replenished the detail flowchart of step S102 in the method for stock；
Fig. 4 is that a kind of experiment running stores of the present invention are automatically replenished the detail flowchart of step S103 in the method for stock；
And
Fig. 5 is the flow chart that another experiment running stores of the present invention are automatically replenished the method for stock.
Embodiment
Example embodiment is described more fully with referring now to accompanying drawing.However, example embodiment can be with a variety of shapes
Formula is implemented, and is not understood as limited to embodiment set forth herein；On the contrary, these embodiments are provided so that the present invention will
Fully and completely, and by the design of example embodiment comprehensively it is communicated to those skilled in the art.Identical is attached in figure
Icon note represents same or similar structure, thus will omit repetition thereof.
Medicine experiment is a kind of system engineering complicated, the cycle is very long, the experiment of large-scale medicine, can continue for many years, by
Examination person participates in jointly more than thousand people, tens hospitals or research center.So how to ensure in so long time, various medicines
It is different using under interval and various different traffic conditions, the research center in hospital or research center has suitably all the time
Stock, it is the problem of a puzzlement each side.
In embodiments of the invention exemplified by testing the medicine in running stores, the operation logic of the present invention, but this hair are introduced
Bright middle experiment running stores can include a kind of a kind of a kind of experiment such as medicine or hospital gauze, syringe, artificial cornea use
Apparatus etc., but be not limited, the invention is not restricted to be served only for medicine to be automatically replenished stock or other hospital gauzes
Be automatically replenished stock, syringe is automatically replenished stock etc..
The treatment medicine granting in general hospital research center mainly carries out putting medicine according to daily patient numbers, puts medicine
Dosage determines according to the state of an illness of patient, and after patient fully recovers, then no longer dispensing.Medicine experiment is then with treating medicine very much not phase
Together, medicine experiment in there is new subject to be added to after screening in experiment weekly, also, have been added to experiment by
Examination person also can periodically get it filled always, and all subjects can be always in medicine experiment, with the progress that medicine is tested, participant
Number can be more and more, experiment running stores usage amount also can be increasing, it is difficult to pass through set one experiment running stores quantity
To adapt to change, so, the present invention coordinates specific predetermined period of replenishing the stock, automatically by gathering historical data in real time
The medicine supplement optimized.
Fig. 1 is the implementation schematic diagram that a kind of experiment running stores of the present invention are automatically replenished the method for stock.Wherein 1 is research
Center, 2 be warehouse, and 3 be subject, and 4 be experiment running stores (i.e. medicine).A kind of experiment running stores that Fig. 2 is the present invention are automatic
The module connection diagram for the method replenished the stock.As illustrated in fig. 1 and 2, a kind of method for being automatically replenished stock of the invention, use
In research center, comprise the following steps：
Step S101, the current stock E in research center 1 and the historical data using the experiment running stores 4 are obtained, is gone through
History data include average screening number A, history screening failure total number of persons B, the history of carrying out weekly and come off total number of persons C and history sieve
Work(total number of persons D is hanked, wherein, A, B, C, D, E are constant.For one kind experiment running stores 4, the experiment running stores 4 are being cured
The current physical holding of stock in the research center 1 of institute is E.Because medicine experiment has strict requirements to subject 3, so weekly all
Some subjects 3 are had by screening, this part subject 3 is to carry out screening number A weekly.Part subject 3 passes through screening
Into experiment, this part subject 3 is that history screens successfully total number of persons D.Remainder subject 3 does not enter not over screening
Enter experiment, this part subject 3 is history screening failure total number of persons B.But with experiment in the subject 3 for entering experiment
Carry out (the ordinary test cycle is very long), may not gone on due to some reasons, individual subject 3, this part subject 3
Come off total number of persons C for history.It can be automatic reading research center to obtain using the mode of the historical data of the experiment running stores 4
1 record data, or various medicines are provided with different electronic tags, are judged by real-time reading electronic labels in research center
Various medicines stock and inbound/outbound process time and data etc., but be not limited.Experiment running stores in the present invention can be with
To include experiment apparatus such as a kind of medicine or a kind of hospital gauze, a kind of syringe, artificial cornea etc., but not as
Limit.Research center in the present invention can be have medicine experiment qualification hospital or pharmaceutical research unit, but not as
Limit.
Step S102, according to default predetermined period T that replenishes the stock, calculate estimated de- in predetermined period T that replenishes the stock
Fall total number of persons L, wherein, T, L are constant.A kind of experiment running stores that Fig. 3 is the present invention are automatically replenished in the method for stock and walked
Rapid S102 detail flowchart.As shown in figure 3, specifically, predetermined period T that replenishes the stock can be according to warehouse and the reality of hospital
Traffic condition and determine, predetermined period of replenishing the stock of each hospital can be different.
Comprise the following steps in step S102：
Step S1021, the screening failure rate F of subject 3 is calculated,
F=B ÷ (B+D).
Step S1022, estimated screening failure total number of persons H is calculated.
H=F × (A × T+B+D).
Step S1023, it is constant to calculate screening failure the number J, J to replenish the stock in predetermined period,
J=H-B.
Step S1024, it is constant to calculate enter weekly group the number G, G to replenish the stock in predetermined period,
G=A-J ÷ T.
Step S1025, the expulsion rate W of subject 3 is calculated,
W=C ÷ D.
Step S1026, it is constant to calculate estimated come off total number of persons K, K,
K=W × (A × T+B+D-H).
Step S1027, the estimated number L that comes off in predetermined period of replenishing the stock is calculated,
L=K-C.
In step s 102, the present invention can averagely carry out screening number A, history screening weekly by what is previously collected
Failure total number of persons B, history come off total number of persons C and history screen successfully total number of persons D and to preset predetermined period T that replenishes the stock automatic
Calculated, it is not necessary to artificial to participate in.The present invention is by historical data, and with reference to replenishing the stock, predetermined period T just can be to supplementing storehouse
The various data deposited in predetermined period T are accurately estimated.By said process, present invention obtains in prediction week of replenishing the stock
The estimated number L that comes off in phase T.
In a change case, in step s 102, step S1025 can be arranged in before step S1021, this order
Replacement do not influence the present invention result.
In a preference, during the estimated total number of persons K that comes off is calculated, can by way of rounding up,
To ensure that K is a constant, so as to the progress subsequently calculated.
Step S103, according to 3 each interview of default subject, using experiment running stores quantity N, (subject 3 can take away every time
N number of experiment running stores), the P weeks interview cycle of subject 3 (subject 3 is every P weekly assembly interviews hospital) calculate enrolled subject 3
Interview number S in predetermined period of replenishing the stock, the interview number i.e. by enrolled subject 3 in predetermined period of replenishing the stock
U and use experiment running stores total amount R, is calculated using experiment running stores total amount R using below equation, wherein, N, S, U, R are equal
For constant, R=[S+U-L × (T ÷ P)] × N.
Fig. 4 is that a kind of experiment running stores of the present invention are automatically replenished the detail flowchart of step S103 in the method for stock.
As shown in figure 4, comprise the following steps in step S103：
Step S1031, interview number S of the enrolled subject 3 in predetermined period of replenishing the stock is calculated
S=(D-C) × (T ÷ P).
In a preferred embodiment, the S in step S1031 can also be intracardiac under study for action according to enrolled subject 3
It is expected that the date for getting it filled in research center is counted in portion's system.Such as：This Monday is registered 5 subjects, a this week
Two it is registered have 3 subjects, this Wednesday is registered 4 subjects, and this Thursday is registered 5 subjects, this
Friday is registered 3 subjects, this Saturday is registered 4 subjects, and this Sunday is registered 5 subjects,
35 subjects are then had in this week to get it filled, by that analogy, it is not necessary to calculated with reference to historical data, it is most accurate also to obtain
The interview number S to replenish the stock in predetermined period.
Step S1032, the interview number U i.e. by enrolled subject 3 in predetermined period of replenishing the stock is calculated
U=[G × T × (T ÷ P+1)] ÷ 2.
The formula is the sum that interview number is distinguished by counting each week enrolled number in predetermined period of replenishing the stock
Formula, be that (each week one as ordered series of numbers of enrolled number difference interview number asks T weeks for the read group total of an ordered series of numbers
Sum), derivation is not introduced specifically.
In a preferred embodiment, can in step S1032, to interview number U carry out round or
Rounded by entering a method.(enter a method to refer to for there is the numeral of fractional part, after fractional part is removed, in reserve part
Last divided numerically adds 1, and the approximation so obtained is approximate value in excess.For example, 4.2 are rounded by entering a method
Obtain 5；7.8 are rounded to obtain 8) by entering a method
Step S1033, calculate using experiment running stores total amount R,
R=[S+U-L × (T ÷ P)] × N.
Obviously, by interview number S of the enrolled subject 3 in predetermined period of replenishing the stock, i.e. by enrolled subject 3
Estimated total number of persons [the L × (T ÷ that comes off in interview number U and predetermined period of replenishing the stock in predetermined period of replenishing the stock
P)], total visit number can be just obtained, each interview of the medicine is then multiplied by using experiment running stores quantity N, with regard to that can be used
Test running stores total amount R.
In a change case, in step s 103, step S1031 can exchange with step S1032 order, this suitable
The replacement of sequence does not influence the result of the present invention.
Step S104, the complementary testing running stores quantity Q of the predetermined period of replenishing the stock is calculated using below equation, so
The request replenished the stock is sent to warehouse afterwards, Q is constant,
Q=R+ (V-E).
Wherein, V is the safety inventory in default research center 1, and V is constant.Safety inventory V in the present invention can be base
Calculated in past history；The value that research center staff sets according to actual conditions can also be responsible for, is not limited.Pass through
Above-mentioned formula and the chemical consumption quantity replenished the stock in predetermined period T is ensure that, can also keep reserving rational safety inventory,
Off-drug is prevented as far as possible.
In a change case, it is constant that Z, which is equal to experiment running stores to transport to research center required cycle, Z,；Use with
Lower formula calculates the safety inventory V, V=A in research center × (N ÷ P) × Z, but is not limited.
In another change case, the safety inventory V in the research center is averagely every equal to the history of the experiment running stores
Week is multiplied by the cycle for testing running stores and being transported to research center and needing using experiment running stores total amount.But it is not limited.
Step S105, warehouse is sent according to the complementary testing running stores quantity Q of the predetermined period of replenishing the stock to research center 1
Medicine.In the present embodiment, step S105 generates waybill 5 according to the complementary testing running stores quantity Q of the predetermined period of replenishing the stock to be believed
Breath, according to replenishing the stock, predetermined period T is periodically transported to warehouse.Waybill 5 can be electronic order, Email, short message or
It is other communication modes, is not limited.The present invention can the complementary testing of Periodic Notice warehouse 2 disappears exactly in this way
Consumption product 4, moment ensure suitable stock.
The experiment running stores of the present invention are automatically replenished the method for stock and got it filled data by gathering the history in research center 1：
It is average to carry out that screening number A, history screening failure total number of persons B, history come off total number of persons C and history screens successfully total people weekly
Number D, experiment running stores quantity N and the interview of subject 3 are used with reference to default predetermined period T that replenishes the stock, 3 each interview of subject
P weeks cycle accurately estimated getting it filled for research center 1 in follow-up predetermined period T that replenishes the stock, finally with reference in default research
The safety inventory V of the heart 1 and current stock E in research center 1 obtains replenishing the stock the complementary testing running stores quantity of predetermined period
Q。
The present invention has abandoned artificial calculating, by the collection to historical data, adaptive physical condition (including warehouse 2 is right
The difference of each hospital is replenished the stock predetermined period T and different 3 interview cycle of the subject P of each experiment running stores 4
The actual conditions in week), after the complementary testing running stores quantity Q of the predetermined period that obtains replenishing the stock, notice warehouse 2 carries out drug delivery.
The method that the method test running stores of the present invention are automatically replenished stock voluntarily can replenish the stock prediction week each
Phase T carries out once-through operation, can also get started progress under artificial require, be not limited.
The method for being automatically replenished stock of the present invention is introduced below by way of battery of tests parameter, for research center, bag
Include following steps：
Step S101, obtain a kind of current stock E=10 for testing running stores in research center and disappeared using the experiment
The historical data of consumption product, historical data include averagely carrying out screening number A=5, history screening failure total number of persons B=5 weekly, going through
History comes off total number of persons C=1 and history screens successfully total number of persons D=20, wherein, A, B, C, D, E are constant.
Step S102, calculated according to default predetermined period T=4 that replenishes the stock estimated in predetermined period T that replenishes the stock
Come off total number of persons L.Comprise the following steps in step S102：
Step S1021, subject screening failure rate F is calculated,
F=B ÷ (B+D)=5 ÷ (5+20)=20%.
Step S1022, estimated screening failure total number of persons H is calculated.
H=F × (A × T+B+D)=20% × (5 × 4+5+20)=9.
Step S1023, it is constant to calculate screening failure the number J, J to replenish the stock in predetermined period,
J=H-B=9-5=4.
Step S1024, it is constant to calculate enter weekly group the number G, G to replenish the stock in predetermined period,
G=A-J ÷ T=5-4 ÷ 4=4.
Step S1025, subject expulsion rate W is calculated,
W=C ÷ D=1 ÷ 20=5%
Step S1026, it is constant to calculate estimated come off total number of persons K, K,
K=W × (A × T+B+D-H)=5% × (5 × 4+5+20-9)=1.8
Calculated for the ease of follow-up, by carrying out the K ≈ 2 that round up to K.
Step S1027, the estimated number L that comes off in predetermined period of replenishing the stock is calculated,
L=K-C=2-1=1.
Step S103, experiment running stores quantity N=1, subject's interview cycle P are used according to default subject per's interview
=2 calculate interview number S of the enrolled subject in predetermined period of replenishing the stock, i.e. by enrolled subject replenish the stock it is pre-
Survey the cycle in interview number U and using experiment running stores total amount R, using below equation come calculate using experiment running stores it is total
R is measured, wherein, N, S, U, R are constant, R=[S+U-L × (T ÷ P)] × N.Comprise the following steps in step S103：
Step S1031, interview number S of the enrolled subject in predetermined period of replenishing the stock is calculated
S=(D-C) × (T ÷ P)=(20-1) × (4 ÷ 2)=38.
Step S1032, the interview number U i.e. by enrolled subject in predetermined period of replenishing the stock is calculated
U=[G × T × (T ÷ P+1)] ÷ 2=[4 × 4 × (4 ÷ 2+1)] ÷ 2=24.
In a preferred embodiment, can in step S1032, to interview number U carry out round or
Rounded by entering a method.(enter a method to refer to for there is the numeral of fractional part, after fractional part is removed, in reserve part
Last divided numerically adds 1.The approximation so obtained is approximate value in excess.For example, 4.2 are rounded by entering a method
Obtain 5；7.8 are rounded to obtain 8) by entering a method
In a further mode of operation, it is understood that be U=4 × 2+4 × 2+4 × 1+4 × 1=24.Wherein, the first two " 4 ×
2 " represent first week and the enrolled subject of second week distinguishes the number of interview hospital, first week with second week it is enrolled each by
Examination person is due to first entering group, and interview hospital is twice before and after 4 weeks energy.Latter two " 4 × 1 " represent the 3rd week and 4th week it is enrolled by
Examination person distinguishes the number of interview hospital, and the 3rd week and the enrolled each subject of 4th week enter group due to after, front and rear only in 4 weeks energy
Interview hospital is once.
Step S1033, calculate using experiment running stores total amount R,
R=[S+U-L × (T ÷ P)] × N=[38+24-1 × (4 ÷ 2)] × 1=60.
Step S104, the complementary testing running stores quantity Q of the predetermined period of replenishing the stock is calculated using below equation, so
The request replenished the stock is sent to warehouse afterwards, Q is constant,
Q=R+ (V-E).
Wherein, Z is equal to experiment running stores and transported to the research center required cycle, and Z is constant, in the present embodiment, Z=2；
The safety inventory V, V=A in research center × (N ÷ P) × Z=5 × (1 ÷ 2) × 2=5 are calculated using below equation, then Q=R
+ (V-E)=60+ (5-10)=55.
Step S105, warehouse is sent according to the complementary testing running stores quantity Q of the predetermined period of replenishing the stock to research center
Medicine.According to above-mentioned parameter, step S105, which includes being generated according to the complementary testing running stores quantity Q of the predetermined period of replenishing the stock, to be transported
Single information, warehouse just needed to transport 55 experiment running stores to research center every 4 weeks (replenish the stock predetermined period T).This hair
It is bright can Periodic Notice warehouse complementary testing running stores exactly in this way, ensure suitable stock.
Fig. 5 is the flow chart that another experiment running stores of the present invention are automatically replenished the method for stock.As shown in figure 5,
In another change case, method that another kind of the invention is automatically replenished stock, for the research center in research center, including with
Lower step：
Step S100, in real-time judge research center a kind of current stock E for testing running stores whether be more than or equal to it is default
Research center safety inventory V, if it is not, then performing step S101.It can be tackled in good time due to sudden by step S100
A large amount of get it filled and caused by the emergency that lacks suddenly of medicine.Also, can also be in time to benefit before by step S100
The complementary testing running stores quantity Q for filling the inventory forecast cycle carries out new adjustment, to adapt to the subject of new time phase
Number changes.
Step S101, obtain a kind of current stock E for testing running stores in research center and use the experiment running stores
Historical data, historical data includes average screening number A, history screening failure total number of persons B, the history of carrying out weekly and comes off total people
Number C and history screen successfully total number of persons D, wherein, A, B, C, D, E are constant.For one kind experiment running stores, the experiment
The current physical holding of stock of the running stores heart under study for action is E.Because medicine experiment has strict requirements to subject, so weekly
There will be some subjects by screening, this part subject is to carry out screening number A weekly.Part subject by screen into
Enter experiment, this part subject is that history screens successfully total number of persons D.Remainder subject is introduced into examination not over screening
Test, this part subject is history screening failure total number of persons B.But with the progress of experiment in the subject for entering experiment
(the ordinary test cycle is very long), may it not gone on due to some reasons, individual subject, this part subject is history
Come off total number of persons C.It can be the automatic record for reading research center to obtain using the mode of the historical data of the experiment running stores
Data, but be not limited.
Step S102, according to default predetermined period T that replenishes the stock, calculate estimated de- in predetermined period T that replenishes the stock
Fall total number of persons L, wherein, T, L are constant.Specifically, replenishing the stock predetermined period T can be according to the reality in warehouse and research center
Border traffic condition and determine, the predetermined period of replenishing the stock in each research center can be different.
Comprise the following steps in step S102：
Step S1021, subject screening failure rate F is calculated,
F=B ÷ (B+D).
Step S1022, estimated screening failure total number of persons H is calculated.
H=F × (A × T+B+D).
Step S1023, it is constant to calculate screening failure the number J, J to replenish the stock in predetermined period,
J=H-B.
Step S1024, it is constant to calculate enter weekly group the number G, G to replenish the stock in predetermined period,
G=A-J ÷ T.
Step S1025, subject expulsion rate W is calculated,
W=C ÷ D
Step S1026, it is constant to calculate estimated come off total number of persons K, K,
K=W × (A × T+B+D-H).
Step S1027, the estimated number L that comes off in predetermined period of replenishing the stock is calculated,
L=K-C.
In step s 102, the present invention can averagely carry out screening number A, history screening weekly by what is previously collected
Failure total number of persons B, history come off total number of persons C and history screen successfully total number of persons D and to preset predetermined period T that replenishes the stock automatic
Calculated, it is not necessary to artificial to participate in.The present invention is by historical data, and with reference to replenishing the stock, predetermined period T just can be to supplementing storehouse
The various data deposited in predetermined period T are accurately estimated.By said process, present invention obtains in prediction week of replenishing the stock
The estimated number L that comes off in phase T.
In a change case, in step s 102, step S1025 can be arranged in before step S1021, this order
Replacement do not influence the present invention result.
In a preference, during the estimated total number of persons K that comes off is calculated, can by way of rounding up,
To ensure that K is a constant, so as to the progress subsequently calculated.
Step S103, experiment running stores quantity N, P weeks interview cycle of subject are used according to default subject per's interview
Calculate interview number S of the enrolled subject in predetermined period of replenishing the stock, enrolled subject is predicted replenishing the stock
Interview number U and use experiment running stores total amount R in cycle, are calculated using experiment running stores total amount using below equation
R, wherein, N, S, U, R are constant, R=[S+U-L × (T ÷ P)] × N.Comprise the following steps in step S103：
Step S1031, interview number S of the enrolled subject in predetermined period of replenishing the stock is calculated
S=(D-C) × (T ÷ P).
Step S1032, the interview number U i.e. by enrolled subject in predetermined period of replenishing the stock is calculated
U=[G × T × (T ÷ P+1)] ÷ 2.
Step S1033, calculate using experiment running stores total amount R,
R=[S+U-L × (T ÷ P)] × N.
Obviously, by interview number S of the enrolled subject in predetermined period of replenishing the stock, enrolled subject is existed
Replenish the stock the estimated total number of persons [L × (T ÷ P)] that comes off in the interview number U in predetermined period and predetermined period of replenishing the stock,
Total visit number just can be obtained, each interview of the medicine is then multiplied by using experiment running stores quantity N, with regard to that can obtain using experiment
Running stores total amount R.
In a change case, in step s 103, step S1031 can exchange with step S1032 order, this suitable
The replacement of sequence does not influence the result of the present invention.
Step S104, the complementary testing running stores quantity Q of the predetermined period of replenishing the stock is calculated using below equation, so
The request replenished the stock is sent to warehouse afterwards, Q is constant,
Q=R+ (V-E).
Wherein, V is the safety inventory in default research center, and V is constant.Replenished the stock by above-mentioned formula and ensure that
Chemical consumption quantity in predetermined period T, it can also keep reserving rational safety inventory, prevent off-drug as far as possible.
In a change case, it is constant that Z, which is equal to experiment running stores to transport to research center required cycle, Z,；Use with
Lower formula calculates the safety inventory V, V=A in research center × (N ÷ P) × Z, but is not limited.
In another change case, the safety inventory V in the research center is averagely every equal to the history of the experiment running stores
Week is multiplied by the cycle for testing running stores and being transported to research center and needing using experiment running stores total amount.But it is not limited.
Step S105, waybill is generated according to the complementary testing running stores quantity Q of the predetermined period of replenishing the stock to send
To warehouse, transport test running stores are replenished the stock at once in warehouse.Other steps are identical with above-mentioned flow, and here is omitted.This
Invention can in this way, (emergency case) notice warehouse complementary testing in time consumption in the case where medicine is close to supply shortage
Product, recover suitable stock as early as possible.
In the present embodiment, strengthen the side that the experiment running stores of the present invention are automatically replenished stock by adding step S100
The flexibility and generation of method lack the timely reaction under inventory status, process of the rationally reply experiment running stores stock control in several years
In various emergency cases, further ensure that the present invention adaptability and reliability.
To sum up, a kind of experiment running stores of the invention be automatically replenished stock method can according to replenish the stock prediction week
Phase, the stock of the adaptive complementary testing running stores of number of subjects, the stock of automatic guarantee test running stores is sufficient but does not waste.
Above content is to combine specific preferred embodiment further description made for the present invention, it is impossible to is assert
The specific implementation of the present invention is confined to these explanations.For general technical staff of the technical field of the invention,
On the premise of not departing from present inventive concept, some simple deduction or replace can also be made, should all be considered as belonging to the present invention's
Protection domain.
Claims (10)
- A kind of 1. method tested running stores and be automatically replenished stock, for research center, it is characterised in that comprise the following steps：Step S101, a kind of current stock E for testing running stores and going through using the experiment running stores in research center are obtained History data, the historical data include average screening number A, history screening failure total number of persons B, the history of carrying out weekly and come off total people Number C and history screen successfully total number of persons D, wherein, A, B, C, D, E are constant；Step S102, according to default predetermined period T that replenishes the stock, calculate and be expected to come off always in predetermined period T that replenishes the stock Number L, wherein, T, L are constant；Step S103, calculated according to default subject per's interview using experiment running stores quantity N, P weeks interview cycle of subject Interview number S of the enrolled subject in predetermined period of replenishing the stock, i.e. by enrolled subject in predetermined period of replenishing the stock Interior interview number U and use experiment running stores total amount R, is calculated using experiment running stores total amount R using below equation, its In, N, S, U, R are constant,R=[S+U-L × (T ÷ P)] × N；Step S104, complementary testing running stores the quantity Q, Ran Houxiang of the predetermined period of replenishing the stock are calculated using below equation Warehouse sends the request replenished the stock, and Q is constant,Q=R+ (V-E)；Wherein, V is the safety inventory in default research center, and V is constant；Step S105, warehouse is supplemented to research center according to the complementary testing running stores quantity Q of the predetermined period of replenishing the stock and tried Test running stores.
- A kind of 2. method tested running stores and be automatically replenished stock according to claim 1, it is characterised in that the step Comprise the following steps in S102：Step S1021, subject screening failure rate F is calculated,F=B ÷ (B+D)；Step S1022, estimated screening failure total number of persons H is calculated,H=F × (A × T+B+D)；Step S1023, it is constant to calculate screening failure the number J, J to replenish the stock in predetermined period,J=H-B；Step S1024, it is constant to calculate enter weekly group the number G, G to replenish the stock in predetermined period,G=A-J ÷ T；Step S1025, subject expulsion rate W is calculated,W=C ÷ D；Step S1026, it is constant to calculate estimated come off total number of persons K, K,K=W × (A × T+B+D-H)；Step S1027, the estimated number L that comes off in predetermined period of replenishing the stock is calculated,L=K-C.
- A kind of 3. method tested running stores and be automatically replenished stock according to claim 2, it is characterised in that the step Comprise the following steps in S103：Step S1031, interview number S of the enrolled subject in predetermined period of replenishing the stock is calculated,S=(D-C) × (T ÷ P)；Step S1032, the interview number U i.e. by enrolled subject in predetermined period of replenishing the stock is calculated,U=[G × T × (T ÷ P+1)] ÷ 2；Step S1033, calculate using experiment running stores total amount R,R=[S+U-L × (T ÷ P)] × N.
- 4. a kind of method tested running stores and be automatically replenished stock according to claim 2, it is characterised in that in the step In rapid S102, step S1025 can be arranged in before the step S1021.
- 5. a kind of method tested running stores and be automatically replenished stock according to claim 3, it is characterised in that in the step In rapid S103, step S1031 can exchange with step S1032 order.
- 6. a kind of method tested running stores and be automatically replenished stock as claimed in any of claims 1 to 5, its feature It is, in the step S104, it is constant that Z, which is equal to experiment running stores to transport to research center required cycle, Z,；Using following Formula calculates the safety inventory V in research center,V=A × (N ÷ P) × Z.
- 7. a kind of method tested running stores and be automatically replenished stock as claimed in any of claims 1 to 5, its feature It is, the safety inventory V in the research center is equal to the history of the experiment running stores averagely weekly using experiment running stores total amount It is multiplied by the cycle that experiment running stores are transported to research center needs.
- 8. a kind of method tested running stores and be automatically replenished stock as claimed in any of claims 1 to 5, its feature It is, the step S105 is replaced with according to predetermined period T weeks of replenishing the stock, and every T weeks, regular transport test running stores were to storehouse Storehouse.
- 9. a kind of method tested running stores and be automatically replenished stock as claimed in any of claims 1 to 5, its feature It is, also includes before the step S101：Step S100, described in real-time judge in research center a kind of current stock E for testing running stores whether be more than or equal to it is default Research center safety inventory V, if it is not, then performing step S101.
- A kind of 10. method tested running stores and be automatically replenished stock according to claim 9, it is characterised in that the step Rapid S105 replaces with warehouse, and transport test running stores are replenished the stock at once.
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