CN107198675A - A kind of double-deck Essence with maintenance and senile-resistant efficacy and preparation method and application - Google Patents
A kind of double-deck Essence with maintenance and senile-resistant efficacy and preparation method and application Download PDFInfo
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- CN107198675A CN107198675A CN201710261734.9A CN201710261734A CN107198675A CN 107198675 A CN107198675 A CN 107198675A CN 201710261734 A CN201710261734 A CN 201710261734A CN 107198675 A CN107198675 A CN 107198675A
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Abstract
The invention belongs to cosmetic technical field, a kind of double-deck Essence with maintenance and senile-resistant efficacy is specifically disclosed, is made up of following raw material by mass percentage：The rilanit specials of 1.0%~2.0%PEG 40, the poly- trimethicone of 5%~19% methyl, 4%~6% carbonic acid dioctyl ester, 0.5%~1.5% cetyl dimethicone, 0.5%~1.5% sunflower（HELIANTHUS ANNUUS）Seed oil, 3%~9% glycerine, 0.1%~0.15% Sodium Hyaluronate, 0.5%~1.5% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 1%~3% polypeptide containing palmityl tripeptides 1 and palmityl tetrapeptide 7,0.5%~1.5% lactobacillus fermentation lysate, 1%~3% glycosphingolipids, mixture, the excess water of 0.8%~1% glycerol caprylate and parahydroxyacet-ophenone and glycerol monolaurate.The present invention is the viscous double-deck system of novel super-low, unique structure, and easy to use.The present invention carries out formulation composition optimization, without essence, anaphylactogen is potentially stimulated without anti-corrosion etc., and formula is gentle non-stimulated, and with good maintenance senile-resistant efficacy.
Description
Technical field
The invention belongs to cosmetic technical field, more particularly, to a kind of bilayer with maintenance and senile-resistant efficacy
Essence and preparation method and application.
Background technology
With advancing age with the increase of life stress, the skin senescence of people can be more obvious.Water loss is more next
More severe, wrinkle is more and more obvious.Skin metabolism slows down, and the moisturizing factor of intradermal is reduced so that intradermal elastic force is fine
Peacekeeping collagenous fibres hypofunction, causes skin tension, elastic force to weaken, skin occur, wrinkle, skin are gloomy, lack cordiality.
The formulation of present cosmetics is varied, aqua；W/o type emulsion, O/W type emulsions；W/o type cream, O/W type cream
Frost；The tens of kinds of systems such as vanishing cream, BB frosts, skin lotion, elite, gel gel.But most of elite liquid products are individual layer system,
Such as：Transparence, emulsion form, the form of product are relatively simple, and double-deck Essence is also more rare on the market（Upper strata white
Emulsion form, lower floor is transparent watery）, it is necessary to which consumer is uniform using preceding rocking.And maintenance and senile-resistant efficacy effect and outward appearance
Combine even more few.
The content of the invention
It is an object of the invention to according to it is of the prior art it is not enough there is provided a kind of with maintenance and senile-resistant efficacy
Double-deck Essence.
Another object of the present invention is to provide the preparation side of the above-mentioned double-deck Essence with maintenance and senile-resistant efficacy
Method.
It is still another object of the present invention to provide the application of the above-mentioned double-deck Essence with maintenance and senile-resistant efficacy.
The purpose of the present invention is achieved through the following technical solutions：
The invention provides a kind of double-deck Essence, it is made up of following raw material by mass percentage：
1.0%~2.0% PEG-40 rilanit specials, the poly- trimethicone of 5%~19% methyl, 4%~6% carbonic acid dioctyl ester,
0.5%~1.5% cetyl dimethicone, 0.5%~1.5% sunflower（HELIANTHUS ANNUUS）Seed oil, 3%~9%
Glycerine, 0.1%~0.15% Sodium Hyaluronate, 0.5%~1.5% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem is carried
Take thing, 1%~3% polypeptide containing palmityl tripeptides -1 and palmityl tetrapeptide -7,0.5%~1.5% lactobacillus fermentation lysate,
1%~3% glycosphingolipids, the mixture of 0.8%~1% glycerol caprylate and parahydroxyacet-ophenone and glycerol monolaurate, surplus
Water.
Preferably, it is made up of following raw material by mass percentage：1.6%PEG-40 rilanit specials, 12% methyl gather
Trimethicone, 5% carbonic acid dioctyl ester, 1% cetyl dimethicone, 1% sunflower（HELIANTHUS ANNUUS）
Seed oil;6% glycerine, 0.12% Sodium Hyaluronate, 66.38% water；1% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/
The polypeptide of stem extraction, 2% containing palmityl tripeptides -1 and palmityl tetrapeptide -7,1% lactobacillus fermentation lysate, 2% glycosphingolipid
The mixture of class, 0.9% glycerol caprylate and parahydroxyacet-ophenone and glycerol monolaurate.
Preferably, in the polypeptide of palmityl tripeptides -1 and palmityl tetrapeptide -7, the content of palmityl tripeptides -1 is 100ppm,
The content of palmityl tetrapeptide -7 is 50ppm.
Present invention simultaneously provides the preparation method of the double-deck Essence, comprise the following steps：
S1. by PEG-40 rilanit specials, the poly- trimethicone of methyl, carbonic acid dioctyl ester, cetyl polydimethylsiloxanes
Alkane, sunflower（HELIANTHUS ANNUUS）Seed oil is placed in container, and stirring is warming up to 75 DEG C~85 DEG C, and insulation is standby, obtains
Oil phase raw material；
S2. glycerine, Sodium Hyaluronate and water are placed in container, stirring is warming up to 85 DEG C~90 DEG C, and insulation is standby, obtains water
Phase raw material；
S3. Aqueous Phase Raw Material is added in emulsifying homogeneous device, stirring is opened, under conditions of 80 DEG C~85 DEG C, by oil phase raw material
In slow suction emulsifier unit, mixed liquor is obtained；Mixed liquor is then subjected to high speed homogenization；
S4. after the completion of homogeneous, it is constant to be kept stirring for speed, cooling；It is subsequently added Mi Luomu（MYROTHAMNUS
FLABELLIFOLIA）Leaf/stem extraction, the polypeptide containing palmityl tripeptides -1 and palmityl tetrapeptide -7, lactobacillus fermentation lysis
The mixture of product, glycosphingolipids, glycerol caprylate and parahydroxyacet-ophenone and glycerol monolaurate, is stirred, discharging, obtains double
Layer Essence.
Preferably, the speed stirred described in step S1 is 600~800rpm；The soaking time is 8~10min.
Preferably, the speed stirred described in step S2 is 600~800rpm；The soaking time is 15~20min.
Preferably, speed of agitator described in step S3 is the rpm of 300r/min~500；The homogeneous speed of the high speed homogenization
For 6000~12000 rpm；The homogenizing time is 20s~40s.
Preferably, the temperature cooled down described in step S4 is 35 DEG C~40 DEG C；The mixing time is 15min~20min.
Described Essence initial appearance is white emulsion, is changed into bottom after standing for transparency liquid, and top is white breast
Liquid, after shaking up still can natural subsidence be double-deck stabilising system；PH is 4.7-5.7, and viscosity is≤200mpa.s, 45 DEG C heat-resisting 24 small
When, it is still double-deck stabilising system to recover after room temperature, is changed into stable white emulsion after jog is even, -18 DEG C are cold-resistant 24 hours, extensive
It is still white stable homogeneous system after multiple room temperature.
Primary raw material information is as follows in the present invention：
PEG-40 rilanit specials：Purchased from BASF AG, saponification number [mgKOH/g]：50.0-50.0, acid number [mgKOH/g]：≤
1.0, hydroxyl value [mgKOH/g]：60.0-75.0；It is white pasty solid under natural botanical source, normal temperature, when temperature is higher than 35 DEG C,
In clear liquid, substantially tasteless is a kind of excellent non-ionic solubilizer and emulsifying agent.
The poly- trimethicone of methyl：Purchased from company of SHIN-ETSU HANTOTAI, refraction index（25℃）：1.3850-1.3860. provide salubrious
The sliding skin sense of silk.
Carbonic acid dioctyl ester：Purchased from purchased from BASF AG, refraction index（20℃）：1.435-1.437, viscosity（25℃）
[mpas]：6.0-8.0, density [g/cm3]:0.890-0.893；It is the grease of plant origin, to the excitant of skin and mucous membrane
It is very low, it is a kind of emollient as mild as a dove.
Cetyl dimethicone：Purchased from EVONIK companies, refraction index（25℃）：1.435-1.442, density
（25℃）[g/ml]：0.865-0.885.
Sunflower（HELIANTHUS ANNUUS）Seed oil：Purchased from Aldivia companies, density（20℃）[g/ml]：0.913-
0.917。
Glycerine：Purchased from Yi Muli companies, relative density（25℃）[g/ml]：>=1.2490, refraction index（20℃）：≥
1.4731, it is the NMF commonly used in skin care item, safety is gentle non-stimulated.
Sodium Hyaluronate：Purchased from Fu Ruida companies, molecule [Da]）：1.0×106 -1.80×106, PH [0.05%]：6.0
~7.5, hyaluronic acid belongs to glutinous polysaccharide, is widely present in the extracellular matrixs of people and vertebrate animal tissues and some streptococcic
In pod membrane, with important physiology and pharmacological action.Can according to the humidity regulation moisture of environment, promote wound without scar
Repair.
Close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction： pH：4.5-6.0. is the master of not dead grass
Active component is wanted, is essential to not dead grass survival in prolonged drought environment, with potent activation and reproducibility, enhancing
Cell viability and metabolism, activating and regenerating Skin Cell, the inoxidizability of enhancing Skin Cell（SOD）, accelerated ageing cell
Synthesis, increase skin moisture retention, elasticity and the smoothness of middle I-type collagen precursor（Experiment in vivo）, mitigate rubefaction, it is right
Anti- erythema（Experiment in vivo）, accelerating wound healing and tissue repair.
The polypeptide of palmityl tripeptides -1 and palmityl tetrapeptide -7:The content of palmityl tripeptides -1 therein is 100ppm, palm
The content of acyl tetrapeptide -7 is 50ppm, pH:4.0-6.0, Density：1.140-1.160 g/cm3 (20 °C), help to lead to
Cross and rebuild fragile papilla dermis network, reduce the light aging of skin, wrinkle can be reduced, improve the pliability and elasticity of skin.
Lactobacillus fermentation lysate:Purchased from Lv Ke companies, pH:6.5-8.5, density（25℃）[g/ml]：1.03-
1.09, refraction index（20℃）：1.380-1.420, probiotics can help improve skin water humidity, stimulate cell function and make
Ripe skin regeneration is obtained, so that skin more soft smooth.
Glycosphingolipids：Purchased from VanAarde companies, pH:5.5-7.0, is extracted from rice bran shell, by making ceramide sugar
Base and it is become water-soluble, it can increase the adhesive capacity of skin keratin, and help supplements the ceramide that skin lacks, and adjust
Skin water loss is saved, the cuticula of drying and the quality of skin sparing barrier is repaired, recovers the natural cover for defense of skin.In skin
It is upper to apply after use, increase the water holding capacity of skin, skin become soft, smooth, recovered elasticity.
The mixture of glycerol caprylate and parahydroxyacet-ophenone and glycerol monolaurate：Trade name is Naturecare
HL-01：Purchased from hundred clean companies, pH:3.0-6.0, contains natural fatty acid glyceride and natural antioxidant para hydroxybenzene second
Ketone, wherein fatty acid glyceride are a kind of active skull cap components being present in human breast milk, can strengthen newborn infant diseases
Resistance and immunity.There is good affinity to skin, not only with moisturizing, moisturizing function, while can effectively control to make up
Most of bacteriums and mould rambunctious in product, can meet the concept of " no added " or require high to formula mildness completely
Cosmetics series.
The present invention is using PEG-40 rilanit specials as emulsified component so that Essence prepared by the present invention, which has, to be compared
Unique double-deck system；Again with the poly- trimethicone of methyl, carbonic acid dioctyl ester, cetyl dimethicone, sunflower
（HELIANTHUS ANNUUS）Seed oil is skin-moisturizing, skin composition, by carrying out these four heterogeneities to be collocated with each other and can make
The softness that Essence of the invention can become skin when keeping preferable spreadability is obtained, while also having preferable moisturizing work(
Effect；Again with glycerine, Sodium Hyaluronate, Mi Luomu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, palmityl three
The polypeptide of peptide -1 and palmityl tetrapeptide -7, lactobacillus fermentation lysate, glycosphingolipids, glycerol caprylate and para hydroxybenzene second
The mixture of ketone and glycerol monolaurate is moisturizing, anti-corrosion and repairs aging ingredient.By the way that these compositions are passed through into strict
Emulsifying process, so as to obtain there is maintenance senile-resistant efficacy and have the i.e. double-deck essence of the double-deck system of stability compared with low viscosity
Magnificent liquid.
Compared with prior art, the present invention has advantages below and beneficial effect：
1st, double-deck Essence of the invention has good maintenance senile-resistant efficacy.
2nd, relatively existing system, the present invention is unique and easy to use for the viscous double-deck architecture of novel super-low.
3rd, the present invention carries out formulation composition optimization, without essence, anaphylactogen is potentially stimulated without anti-corrosion etc., and formula is gentle stingless
Swash.
Embodiment
The present invention is further illustrated below in conjunction with specific embodiment, but embodiment does not do any type of to the present invention
Limit.Unless stated otherwise, the reagent of the invention used, method and apparatus is the art conventional reagent, methods and apparatus.
Unless stated otherwise, agents useful for same and material of the present invention are purchased in market.
Embodiment 1:
A kind of double-deck Essence with maintenance and senile-resistant efficacy, is made up of following component by mass percentage：
Component A：1.0%PEG-40 rilanit specials, the poly- trimethicone of 5% methyl, 4% carbonic acid dioctyl ester, 0.5% cetyl
Dimethyl silicone polymer, 0.5% sunflower（HELIANTHUS ANNUUS）Seed oil;
B component：3% glycerine, 0.1% Sodium Hyaluronate, 82.1% water；
Component C：0.5% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 1% containing palmityl tripeptides -1 and
The polypeptide of palmityl tetrapeptide -7,0.5% lactobacillus fermentation lysate, 1% glycosphingolipids, 0.8% glycerol caprylate and to hydroxyl
The mixture of acetophenone and glycerol monolaurate；
The preparation method of the Essence：
（1）Component A is stirred（800rpm）75 DEG C~85 DEG C are warming up to, insulation 10min is standby, obtains oil phase raw material；
（2）B component is placed in container, stirred（600rpm）85 DEG C~90 DEG C are warming up to, insulation 20min is standby, obtains aqueous phase
Raw material；
（3）B component raw material is added in emulsifying homogeneous device, stirring is opened, it is under conditions of 80 DEG C~85 DEG C, component A is former
In the slow suction emulsifier unit of material, mixed liquor is obtained；Open homogeneous 30s, 9000rpm;
（4）After the completion of homogeneous, it is constant to be kept stirring for speed, is cooled to 40 DEG C, adds component C, stirs 15min, and discharging obtains double
Layer Essence.
The Essence outward appearance just prepared is white emulsion, and PH is 5.18, and viscosity is 80mpa.s；It is quiet by 12h under normal temperature
Put, Essence is divided into top white emulsion and lower transparent liquid, the height ratio of white layer and hyaline layer is 1.0:9.0, it is transparent
Some muddinesses of layer.Centrifugation test（3000r/min,30min）：Without water-oil separating without precipitation, it is divided into top white emulsion and bottom
Transparency liquid.
Heat resistance is tested：The Essence just prepared is positioned in 45 DEG C of environment heat-resisting 24 hours, no water-oil separating without
Precipitation, is divided into top white emulsion and lower transparent liquid.
Cold tolerance is tested：The Essence just prepared is positioned in -18 DEG C of environment and resisted cold 24 hours, recovers essence after room temperature
Magnificent liquid is still white emulsion.
Embodiment 2
A kind of double-deck Essence with maintenance and senile-resistant efficacy, is made up of following component by mass percentage：
Component A：1.6%PEG-40 rilanit specials, the poly- trimethicone of 12% methyl, 5% carbonic acid dioctyl ester, 1% cetyl gather
Dimethyl siloxane, 1% sunflower（HELIANTHUS ANNUUS）Seed oil;
B component：6% glycerine, 0.12% Sodium Hyaluronate, 66.38% water；
Component C：1% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 2% contain palmityl tripeptides -1 and palm fibre
The polypeptide of palmitic acid acyl tetrapeptide -7,1% lactobacillus fermentation lysate, 2% glycosphingolipids, 0.9% glycerol caprylate and para hydroxybenzene second
The mixture of ketone and glycerol monolaurate；
The preparation method of the Essence：
（1）Component A is stirred（800rpm）75 DEG C~85 DEG C are warming up to, insulation 10min is standby, obtains oil phase raw material；
（2）B component is placed in container, stirred（600rpm）85 DEG C~90 DEG C are warming up to, insulation 20min is standby, obtains aqueous phase
Raw material；
（3）B component raw material is added in emulsifying homogeneous device, stirring is opened, it is under conditions of 80 DEG C~85 DEG C, component A is former
In the slow suction emulsifier unit of material, mixed liquor is obtained；Open homogeneous 30s, 9000rpm;
（4）After the completion of homogeneous, it is constant to be kept stirring for speed, is cooled to 40 DEG C, adds component C, stirs 15min, and discharging obtains double
Layer Essence.
The Essence outward appearance just prepared is white emulsion, and PH is 5.23, and viscosity is 150mpa.s；It is quiet by 12h under normal temperature
Put, Essence is divided into top white emulsion and lower transparent liquid, the height ratio of white layer and hyaline layer is 3.5:6.5, it is transparent
The transparency of layer is preferable.Centrifugation test（3000r/min,30min）：Without water-oil separating without precipitation, be divided into top white emulsion and
Lower transparent liquid.
Heat resistance is tested：The Essence just prepared is positioned in 45 DEG C of environment heat-resisting 24 hours, no water-oil separating without
Precipitation, is divided into top white emulsion and lower transparent liquid.
Cold tolerance is tested：The Essence just prepared is positioned in -18 DEG C of environment and resisted cold 24 hours, recovers essence after room temperature
Magnificent liquid is still white emulsion.
Embodiment 3
A kind of double-deck Essence with maintenance and senile-resistant efficacy, is made up of following component by mass percentage：
Component A：2.0%PEG-40 rilanit specials, the poly- trimethicone of 19% methyl, 6% carbonic acid dioctyl ester, 1.5% cetyl
Dimethyl silicone polymer, 1.5% sunflower（HELIANTHUS ANNUUS）Seed oil;
B component：9% glycerine, 0.15% Sodium Hyaluronate, 50.85% water；
Component C：1.5% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 3% containing palmityl tripeptides -1 and
The polypeptide of palmityl tetrapeptide -7,1.5% lactobacillus fermentation lysate, 3% glycosphingolipids, 1.0% glycerol caprylate and to hydroxyl
The mixture of acetophenone and glycerol monolaurate；
The preparation method of the Essence：
（1）Component A is stirred（800rpm）75 DEG C~85 DEG C are warming up to, insulation 10min is standby, obtains oil phase raw material；
（2）B component is placed in container, stirred（600rpm）85 DEG C~90 DEG C are warming up to, insulation 20min is standby, obtains aqueous phase
Raw material；
（3）B component raw material is added in emulsifying homogeneous device, stirring is opened, it is under conditions of 80 DEG C~85 DEG C, component A is former
In the slow suction emulsifier unit of material, mixed liquor is obtained；Open homogeneous 30s, 9000rpm;
（4）After the completion of homogeneous, it is constant to be kept stirring for speed, is cooled to 40 DEG C, adds component C, stirs 15min, and discharging obtains double
Layer Essence.
The Essence outward appearance just prepared is white emulsion, and PH is 5.21, and viscosity is 260mpa.s；It is quiet by 12h under normal temperature
Put, Essence is divided into top white emulsion and lower transparent liquid, the height ratio of white layer and hyaline layer is 4.5:5.5, it is transparent
The transparency of layer is preferable.Centrifugation test（3000r/min,30min）：Without water-oil separating without precipitation, be divided into top white emulsion and
Lower transparent liquid.
Heat resistance is tested：The Essence just prepared is positioned in 45 DEG C of environment heat-resisting 24 hours, no water-oil separating without
Precipitation, is divided into top white emulsion and lower transparent liquid.
Cold tolerance is tested：The Essence just prepared is positioned in -18 DEG C of environment and resisted cold 24 hours, recovers essence after room temperature
Magnificent liquid is still white emulsion.
Embodiment 4
A kind of double-deck Essence with maintenance and senile-resistant efficacy, is made up of following component by mass percentage：
Component A：1.6%PEG-40 rilanit specials, the poly- trimethicone of 12% methyl, 5% carbonic acid dioctyl ester, 1% cetyl gather
Dimethyl siloxane, 1% sunflower（HELIANTHUS ANNUUS）Seed oil;
B component：6% glycerine, 0.12% Sodium Hyaluronate, 66.38% water；
Component C：1% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 2% contain palmityl tripeptides -1 and palm fibre
The polypeptide of palmitic acid acyl tetrapeptide -7,1% lactobacillus fermentation lysate, 2% glycosphingolipids, 0.9% glycerol caprylate and para hydroxybenzene second
The mixture of ketone and glycerol monolaurate；
The preparation method of the Essence：
（1）Component A is stirred（800rpm）75 DEG C~85 DEG C are warming up to, insulation 10min is standby, obtains oil phase raw material；
（2）B component is placed in container, stirred（600rpm）85 DEG C~90 DEG C are warming up to, insulation 20min is standby, obtains aqueous phase
Raw material；
（3）B component raw material is added in emulsifying homogeneous device, stirring is opened, it is under conditions of 80 DEG C~85 DEG C, component A is former
In the slow suction emulsifier unit of material, mixed liquor is obtained；Open homogeneous 20s, 9000rpm;
（4）After the completion of homogeneous, it is constant to be kept stirring for speed, is cooled to 40 DEG C, adds component C, stirs 15min, and discharging obtains double
Layer Essence.
The Essence outward appearance just prepared is white emulsion, and PH is 5.23, and viscosity is 150mpa.s；It is quiet by 12h under normal temperature
Put, Essence is divided into top white emulsion and lower transparent liquid, the height ratio of white layer and hyaline layer is 3.5:6.5, it is transparent
The transparency of layer is preferable.Centrifugation test（3000r/min,30min）：There are slight water-oil separating, no precipitation.
Heat resistance is tested：The Essence just prepared is positioned in 45 DEG C of environment heat-resisting 24 hours, no water-oil separating without
Precipitation, is divided into top white emulsion and lower transparent liquid.
Cold tolerance is tested：The Essence just prepared is positioned in -18 DEG C of environment and resisted cold 24 hours, recovers essence after room temperature
Magnificent liquid is still white emulsion.
Embodiment 5
A kind of double-deck Essence without anti-corrosion without essence with moisture-keeping efficacy, by following component group by mass percentage
Into：
Component A：1.6%PEG-40 rilanit specials, the poly- trimethicone of 12% methyl, 5% carbonic acid dioctyl ester, 1% cetyl gather
Dimethyl siloxane, 1% sunflower（HELIANTHUS ANNUUS）Seed oil;
B component：6% glycerine, 0.12% Sodium Hyaluronate, 66.38% water；
Component C：1% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 2% contain palmityl tripeptides -1 and palm fibre
The polypeptide of palmitic acid acyl tetrapeptide -7,1% lactobacillus fermentation lysate, 2% glycosphingolipids, 0.9% glycerol caprylate and para hydroxybenzene second
The mixture of ketone and glycerol monolaurate；
The preparation method of the Essence：
（1）Component A is stirred（800rpm）75 DEG C~85 DEG C are warming up to, insulation 10min is standby, obtains oil phase raw material；
（2）B component is placed in container, stirred（600rpm）85 DEG C~90 DEG C are warming up to, insulation 20min is standby, obtains aqueous phase
Raw material；
（3）B component raw material is added in emulsifying homogeneous device, stirring is opened, it is under conditions of 80 DEG C~85 DEG C, component A is former
In the slow suction emulsifier unit of material, mixed liquor is obtained；Open homogeneous 40s, 9000rpm;
（4）After the completion of homogeneous, it is constant to be kept stirring for speed, is cooled to 40 DEG C, adds component C, stirs 15min, and discharging obtains double
Layer Essence.
The Essence outward appearance just prepared is white emulsion, and PH is 5.23, and viscosity is 150mpa.s；It is quiet by 12h under normal temperature
Put, Essence is divided into top white emulsion and lower transparent liquid, the height ratio of white layer and hyaline layer is 3.0:7.0, it is transparent
The transparency of layer is preferable.Centrifugation test（3000r/min,30min）：Without water-oil separating without precipitation, be divided into top white emulsion and
Lower transparent liquid.
Heat resistance is tested：The Essence just prepared is positioned in 45 DEG C of environment heat-resisting 24 hours, no water-oil separating without
Precipitation, is divided into top white emulsion and lower transparent liquid.
Cold tolerance is tested：The Essence just prepared is positioned in -18 DEG C of environment and resisted cold 24 hours, recovers essence after room temperature
Magnificent liquid is still white emulsion.
Embodiment 6
A kind of double-deck Essence without anti-corrosion without essence with moisture-keeping efficacy, by following component group by mass percentage
Into：
Component A：1.6%PEG-40 rilanit specials, the poly- trimethicone of 12% methyl, 5% carbonic acid dioctyl ester, 1% cetyl gather
Dimethyl siloxane, 1% sunflower（HELIANTHUS ANNUUS）Seed oil;
B component：6% glycerine, 0.12% Sodium Hyaluronate, 66.38% water；
Component C：1% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 2% contain palmityl tripeptides -1 and palm fibre
The polypeptide of palmitic acid acyl tetrapeptide -7,1% lactobacillus fermentation lysate, 2% glycosphingolipids, 0.9% glycerol caprylate and para hydroxybenzene second
The mixture of ketone and glycerol monolaurate；
The preparation method of the Essence：
（1）Component A is stirred（800rpm）75 DEG C~85 DEG C are warming up to, insulation 10min is standby, obtains oil phase raw material；
（2）B component is placed in container, stirred（600rpm）85 DEG C~90 DEG C are warming up to, insulation 20min is standby, obtains aqueous phase
Raw material；
（3）B component raw material is added in emulsifying homogeneous device, stirring is opened, it is under conditions of 80 DEG C~85 DEG C, component A is former
In the slow suction emulsifier unit of material, mixed liquor is obtained；Open homogeneous 30s, 6000rpm;
（4）After the completion of homogeneous, it is constant to be kept stirring for speed, is cooled to 40 DEG C, adds component C, stirs 15min, and discharging obtains double
Layer Essence.
The Essence outward appearance just prepared is white emulsion, and PH is 5.23, and viscosity is 150mpa.s；It is quiet by 12h under normal temperature
Put, Essence is divided into top white emulsion and lower transparent liquid, the height ratio of white layer and hyaline layer is 4.0:6.0, it is transparent
The transparency of layer is preferable.Centrifugation test（3000r/min,30min）：There are slight water-oil separating, no precipitation.
Heat resistance is tested：The Essence just prepared is positioned in 45 DEG C of environment heat-resisting 24 hours, no water-oil separating without
Precipitation, is divided into top white emulsion and lower transparent liquid.
Cold tolerance is tested：The Essence just prepared is positioned in -18 DEG C of environment and resisted cold 24 hours, recovers essence after room temperature
Magnificent liquid is still white emulsion.
Embodiment 7
A kind of double-deck Essence without anti-corrosion without essence with moisture-keeping efficacy, by following component group by mass percentage
Into：
Component A：1.6%PEG-40 rilanit specials, the poly- trimethicone of 12% methyl, 5% carbonic acid dioctyl ester, 1% cetyl gather
Dimethyl siloxane, 1% sunflower（HELIANTHUS ANNUUS）Seed oil;
B component：6% glycerine, 0.12% Sodium Hyaluronate, 66.38% water；
Component C：1% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, 2% contain palmityl tripeptides -1 and palm fibre
The polypeptide of palmitic acid acyl tetrapeptide -7,1% lactobacillus fermentation lysate, 2% glycosphingolipids, 0.9% glycerol caprylate and para hydroxybenzene second
The mixture of ketone and glycerol monolaurate；
The preparation method of the Essence：
（1）Component A is stirred（800rpm）75 DEG C~85 DEG C are warming up to, insulation 10min is standby, obtains oil phase raw material；
（2）B component is placed in container, stirred（600rpm）85 DEG C~90 DEG C are warming up to, insulation 20min is standby, obtains aqueous phase
Raw material；
（3）B component raw material is added in emulsifying homogeneous device, stirring is opened, it is under conditions of 80 DEG C~85 DEG C, component A is former
In the slow suction emulsifier unit of material, mixed liquor is obtained；Open homogeneous 30s, 12000rpm;
（4）After the completion of homogeneous, it is constant to be kept stirring for speed, is cooled to 40 DEG C, adds component C, stirs 15min, and discharging obtains double
Layer Essence.
The Essence outward appearance just prepared is white emulsion, and PH is 5.23, and viscosity is 150mpa.s；It is quiet by 12h under normal temperature
Put, Essence is divided into top white emulsion and lower transparent liquid, the height ratio of white layer and hyaline layer is 3.0:7.0, it is transparent
The transparency of layer is preferable.Centrifugation test（3000r/min,30min）：Without water-oil separating without precipitation, be divided into top white emulsion and
Lower transparent liquid.
Heat resistance is tested：The Essence just prepared is positioned in 45 DEG C of environment heat-resisting 24 hours, no water-oil separating without
Precipitation, is divided into top white emulsion and lower transparent liquid.
Cold tolerance is tested：The Essence just prepared is positioned in -18 DEG C of environment and resisted cold 24 hours, recovers essence after room temperature
Magnificent liquid is still white emulsion.
From the embodiment 1 ~ 7 given, optimal white layer and transparent layer height ratio are close to 4.0:6.0 is the most suitable, and
And for transparency, embodiment 2 is better than embodiment 3.
Comparative example
Comparative example a：Lack PEG-40 rilanit specials, the PEG-40 rilanit specials of missing replace with water, other raw materials into
Point, consumption and production technology it is same as Example 2, as a result there is the transparent oil reservoir in upper strata（Water-oil separating）, do not reach double-deck steady
Determine system；
Comparative example b：Lack close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction, the close Luo Mu of missing
（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction is replaced with water, other material compositions, consumption and production technology
It is same as Example 2, as a result show that pH, normal temperature stand every physical and chemical indexs such as 12h, heat-resisting cold-resistant test big with embodiment 2
Cause identical；
Comparative example c：Lack the polypeptide of palmityl tripeptides -1 and palmityl tetrapeptide -7, the palmityl tripeptides -1 and palmityl of missing
The polypeptide of tetrapeptide -7 is replaced with water, and other material compositions, consumption and production technology are same as Example 2, as a result show pH, often
It is roughly the same with embodiment 2 that temperature stands every physical and chemical indexs such as 12h, heat-resisting cold-resistant test；
Comparative example d：Lactobacillus fermentation lysate is lacked, the lactobacillus fermentation lysate of missing is replaced with water, other
Material composition, consumption and production technology are same as Example 2, as a result show that pH, normal temperature stand 12h, heat-resisting cold-resistant test etc.
Every physical and chemical index is roughly the same with embodiment 2；
Comparative example e:Glycosphingolipids is lacked, the glycosphingolipids of missing is replaced with water, other material compositions, consumption and production work
Skill is same as Example 2, as a result show pH, normal temperature stand every physical and chemical indexs such as 12h, heat-resisting cold-resistant test with embodiment 2
It is roughly the same；
Comparative example f：Lack the polypeptide of palmityl tripeptides -1 and palmityl tetrapeptide -7, the palmityl tripeptides -1 and palmityl of missing
The close Luo Mu of the polypeptide of tetrapeptide -7（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem extraction is replaced, other material compositions,
Consumption and production technology are same as Example 2, as a result show that pH, normal temperature stand every physics and chemistry such as 12h, heat-resisting cold-resistant test and referred to
Mark is roughly the same with embodiment 2；
Maintenance skin barrier is carried out to embodiment 2, comparative example b, comparative example c, comparative example d, comparative example e and anti-aging performance is surveyed
Examination, test result is as shown in table 1, table 2：
Table 1：Maintenance skin barrier performance test
Subject's number of cases n=96, the time of trying out is 2 weeks, upper table data for it is on probation preceding to after tested 1 week and it is tested 2 weeks after corresponding refer to
Target average value；
TEWL values reflection speed of the deep skin moisture through skin losses of skin, skin barrier function is better, is worth smaller；
P value≤0.05, it is believed that there were significant differences before on probation and after trying out.
Table 2：Anti-aging performance test
| Wrinkle area reduction | Wrinkle depth decrement | Wrinkle quantity decrement | |
| Embodiment 2 | 27.5% | 22.3% | 23.6% |
| Comparative example b | 23.7% | 19.2% | 18.6% |
| Comparative example c | 8.3% | 7.9% | 8.7% |
| Comparative example d | 20.1% | 18.2% | 17.9% |
| Comparative example e | 19.3% | 18.4% | 17.2% |
| Comparative example f | 12.3% | 13.4% | 12.6% |
Subject's number of cases n=96, the time of trying out is 4 weeks, and upper table data are the average value of corresponding index after tested 4 weeks；
As can be seen from the above table, even if comparative example c and comparative example f contrast are it can be found that use close Luo Mu（MYROTHAMNUS
FLABELLIFOLIA）Leaf/stem extraction substitutes the palmityl tripeptides -1 of missing and the polypeptide of palmityl tetrapeptide -7, and its is physical
Difference is little on shape, but is still not so good as the effect of embodiment 2, above-mentioned close Luo Mu on skin repair and anti-aging effects
（MYROTHAMNUS FLABELLIFOLIA）The polypeptide of leaf/stem extraction and palmityl tripeptides -1 and palmityl tetrapeptide -7 is answered
Match somebody with somebody, the maintenance and anti-aging to double-deck Essence serve cooperative effect, the embodiment 2 that the raw material that the present invention is provided is not lost really resists
Aging effects are best.
Above-described embodiment is preferably embodiment, but embodiments of the present invention are not by above-described embodiment of the invention
Limitation, other any Spirit Essences without departing from the present invention and the change made under principle, modification, replacement, combine, simplification,
Equivalent substitute mode is should be, is included within protection scope of the present invention.
Claims (8)
1. a kind of double-deck Essence with maintenance and senile-resistant efficacy, it is characterised in that by it is following by mass percentage
Raw material is constituted：
1.0%~2.0% PEG-40 rilanit specials, the poly- trimethicone of 5%~19% methyl, 4%~6% carbonic acid dioctyl ester,
0.5%~1.5% cetyl dimethicone, 0.5%~1.5% sunflower（HELIANTHUS ANNUUS）Seed oil, 3%~9%
Glycerine, 0.1%~0.15% Sodium Hyaluronate, 0.5%~1.5% close Luo Mu（MYROTHAMNUS FLABELLIFOLIA）Leaf/stem is carried
Take thing, 1%~3% polypeptide containing palmityl tripeptides -1 and palmityl tetrapeptide -7,0.5%~1.5% lactobacillus fermentation lysate,
1%~3% glycosphingolipids, the mixture of 0.8%~1% glycerol caprylate and parahydroxyacet-ophenone and glycerol monolaurate, surplus
Water.
2. double-deck Essence according to claim 1, it is characterised in that by following raw material group by mass percentage
Into：1.6%PEG-40 rilanit specials, the poly- trimethicone of 12% methyl, 5% carbonic acid dioctyl ester, 1% cetyl poly dimethyl
Siloxanes, 1% sunflower（HELIANTHUS ANNUUS）Seed oil;6% glycerine, 0.12% Sodium Hyaluronate, 66.38% water；1% is close
Luo Mu（MYROTHAMNUS FLABELLIFOLIA）It is leaf/stem extraction, 2% many containing palmityl tripeptides -1 and palmityl tetrapeptide -7
Peptide, 1% lactobacillus fermentation lysate, 2% glycosphingolipids, 0.9% glycerol caprylate and parahydroxyacet-ophenone and glycerine bay
The mixture of acid esters.
3. double-deck Essence according to claim 1 or 2, it is characterised in that palmityl tripeptides -1 and palmityl tetrapeptide -7
Polypeptide in, the content of palmityl tripeptides -1 be 100ppm, the content of palmityl tetrapeptide -7 be 50ppm.
4. a kind of preparation method of the double-deck Essence with maintenance and senile-resistant efficacy, it is characterised in that comprise the following steps：
S1. by PEG-40 rilanit specials, the poly- trimethicone of methyl, carbonic acid dioctyl ester, cetyl polydimethylsiloxanes
Alkane, sunflower（HELIANTHUS ANNUUS）Seed oil is placed in container, and stirring is warming up to 75 DEG C~85 DEG C, and insulation is standby, obtains
Oil phase raw material；
S2. glycerine, Sodium Hyaluronate and water are placed in container, stirring is warming up to 85 DEG C~90 DEG C, and insulation is standby, obtains water
Phase raw material；
S3. Aqueous Phase Raw Material is added in emulsifying homogeneous device, stirring is opened, under conditions of 80 DEG C~85 DEG C, by oil phase raw material
In slow suction emulsifier unit, mixed liquor is obtained；Mixed liquor is then subjected to high speed homogenization；
S4. after the completion of homogeneous, it is constant to be kept stirring for speed, cooling；It is subsequently added Mi Luomu（MYROTHAMNUS
FLABELLIFOLIA）Leaf/stem extraction, the polypeptide containing palmityl tripeptides -1 and palmityl tetrapeptide -7, lactobacillus fermentation lysis
The mixture of product, glycosphingolipids, glycerol caprylate and parahydroxyacet-ophenone and glycerol monolaurate, is stirred, discharging, obtains double
Layer Essence.
5. preparation method according to claim 4, it is characterised in that the speed stirred described in step S1 is 600~
800rpm；The soaking time is 8~10min.
6. preparation method according to claim 4, it is characterised in that the speed stirred described in step S2 is 600~
800rpm；The soaking time is 15~20min.
7. preparation method according to claim 4, it is characterised in that speed of agitator described in step S3 be 300r/min~
500 rpm；The homogeneous speed of the high speed homogenization is 6000~12000 rpm；The homogenizing time is 20s~40s.
8. preparation method according to claim 4, it is characterised in that the temperature cooled down described in step S4 is 35 DEG C~40
℃；The mixing time is 15min~20min.
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