CN109481337A - A kind of moisturizing moisturizer and preparation method thereof containing ceramide - Google Patents

A kind of moisturizing moisturizer and preparation method thereof containing ceramide Download PDF

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CN109481337A
CN109481337A CN201811300968.0A CN201811300968A CN109481337A CN 109481337 A CN109481337 A CN 109481337A CN 201811300968 A CN201811300968 A CN 201811300968A CN 109481337 A CN109481337 A CN 109481337A
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skin
extract
ceramide
glycerol
moisturizing
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刘丽江
傅建斌
易黎明
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Guangzhou Li Li Cosmetics Biotechnology Co Ltd
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Guangzhou Li Li Cosmetics Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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Abstract

The present invention relates to cosmetic technical fields, specifically a kind of moisturizing moisturizer and preparation method thereof containing ceramide, is prepared by following components: caprylic/capric triglyceride, isopropyl palmitate, dimethyl silicone polymer, tocopherol acetate, ceramide, glycerin monostearate, cetostearyl alcohol, carbomer, glycerol, C12-13 alcohol phosphate potassium, reed fragrant plant glue, sodium hydroxide, GC-04, essence, Sodium Hyaluronate, various plants extract and water.Moisturizing moisturizer of the present invention containing ceramide can make skin long-time replenishing water and preserving moisture, have the effect of preventing anaphylaxis dermatosis and inhibit melanin foxiness, and use pure natural components, do not add preservative.

Description

A kind of moisturizing moisturizer and preparation method thereof containing ceramide
Technical field
The present invention relates to cosmetic technical field, specifically a kind of moisturizing moisturizer and its preparation side containing ceramide Method.
Background technique
Moisturizing emulsion has good moisturizing effect and damping effect, and skin can be allowed to keep moistening.The lotion of early stage is water packet Oil type emulsion mostly uses potash soap to make emulsifier, but meeting retrogradation during storage, is not easy to pour out from bottle, uses ten in recent years Glycol sulfate salt or nonionic emulsifier, can be made the good lotion of stability, and moisturizing emulsion has certain Mobility, shape is quite like honey, so gain the name.Lotion water content is larger, can sufficiently keep the skin wet for skin, lotion also contains on a small quantity Oil, can moisturize the skin.But existing moisturizing emulsion can not be applicable in a variety of skin quality, can only play the work of surface moisturizing It cannot be continued with perhaps replenishing water and preserving moisture too long or fuel-displaced.
Summary of the invention
In order to overcome the above the deficiencies in the prior art, one of task of the invention is to provide a kind of moisturizing containing ceramide Moisturizer can make skin long-time replenishing water and preserving moisture, have the effect of preventing anaphylaxis dermatosis and inhibit melanin foxiness, and Using pure natural components, preservative is not added;The two of task of the present invention are to provide a kind of moisturizing moisturizer containing ceramide Preparation method.
One of task of the present invention is achieved through the following technical solutions:
A kind of moisturizing moisturizer containing ceramide, is prepared by the component of following quality proportionings:
Caprylic/capric triglyceride: 15-18%;
Isopropyl palmitate: 2.8-3.2%;
Dimethyl silicone polymer: 1.8-2.1%;
Tocopherol acetate: 0.5-1%;
Ceramide: 0.5-1%;
Glycerin monostearate: 2-2.2%;
Cetostearyl alcohol: 2.6-2.9%;
Carbomer: 0.128-0.132%;
Glycerol: 9-11%;
C12-13 alcohol phosphate potassium: 3-3.5%;
Reed fragrant plant glue: 2-5%;
Sodium hydroxide: 0.018-0.02%;
GC-04:0.5-1%;
Essence: 0.2-0.4%;
Sodium Hyaluronate: 0.05-0.1%;
Various plants extract: 2-3%;
Water: 45.448-57.904%.
The main component of the various plants extract be lady's bower (CLEMATIS VITALBA) leaf extract, Sub- opium poppy in peach (PRUNUS PERSICA) berry extract, hundred golden flower (CENTAURIUM ERYTHRAEA) extract, horse ladder (ROMNEYA COULTERII) flower extract, foreign ivy (HEDERA HELIX) extract and butanediol.Wherein: grape leaf Clematis (CLEMATIS VITALBA) leaf extract can releive dry and chap of the skin skin, reduce other ingredients to the thorn of skin Swash;Peach berry extract has proliferation function to epidermal keratinocyte, to the inhibition that oxynitrides generates, furthermore antioxidant and can be compared with The water content for significantly improving cuticula, shows that peach extract has good skin-active and anti-ageing type energy, can be used for because of dry skin Caused by skin aging, actin-myosin is a model of simulated skin corium construction, and peach extract has receipts to it Contracting effect, can indicate that it has skin tightening effect;Hundred golden flower extracts are that middle extraction is spent from platinum, and extract mainly contains chlorogenic acid etc. Functional component has extensive bacteriostasis, can supplement pure moisture for skin, the skin being easily dried of releiving is founded strong Health skin;Foreign ivy extract is the natural products extracted from foreign ivy, has inhibition to the activity of apolipoprotein, can be with Reduce underarm odor, have inhibition to Corynebacterium xerosis, can be used for pressing down it is smelly, play the role of inhibit sebum secretion, be suitable for oiliness skin The nursing of skin.
It is preferred that the water is deionized water, used as solvent.
Caprylic/capric triglyceride in the present invention is the ingredient of GTCC, is that height clearly spends tasteless grease, belongs to palm oil Or the derivative of coconut oil, it is extracted using hot fractional method.Since it and human skin have compatible feature, there is non-greasy matter Sense, its extensibility can be improved by being added in creams or lotion, had lubrication and made the effect of skin softness, and had the function of filtering ultraviolet Can, can make emollients, solvent, permeation enhancers come using.
Isopropyl palmitate in the present invention is the ingredient of IPP, this can increase production at low molecule monoesters class is belonged to Product ductility, tends to smear out and has no greasy feeling, by moisturizing and affected skin can be promoted to restore, eliminate nail fungi, moreover it is possible to pre- Anti- eczema and dermatitis.
Dimethyl silicone polymer in the present invention is the ingredient of DC500, and dimethyl silicone polymer is also known as dimeticone, profit Slip energy is good, can form one layer of uniform protective film with waterproofness after applying skin, but without any sticky and greasy Feeling, glossiness is good;The performance of ultra-violet radiation resisting is good, it under ultraviolet light will not oxidation deterioration and cause to skin irritatin Effect;Antistatic property is good, experiments have shown that, the skin electrostatic for the face cream containing polysiloxanes that nuzzles up all is eliminated, and is had apparent Dust-proof effect;Good permeability, even if forming silicone film on the skin nor affects on sweat discharge;It has flavors and fragrances slow Fixation effect is released, thus protects longer stability height of fragrant phase, it is chemically inert, to other compositions of cosmetics, especially active constituent There is no any adverse effect matching good, it is nontoxic, odorless, tasteless, stimulation and allergy will not be caused to skin, it is highly-safe, it is right Certain skin diseases have certain curative effect, such as sweating difficulty type eczema neurodermatitis and occupational dermatitis.
Tocopherol acetate in the present invention is the ingredient of VE oil, and tocopherol acetate belongs to the derivative of vitamin E, It is used as antioxidant, there is good antioxidant effect, it is to seek well to skin that it, which is a kind of oil-soluble natural materials, Moisturizing agent is supported, makes an addition in skin care products, can be avoided the rancid oxidation of grease, stabilizes grease, in moisturizing and maintains connective tissue, And skin is protected not had fine performance by uv damage, which can make skin soft-touch and keep skin moisture, Promoting wound healing, prevention inflammation prevents the coarse chap of skin, improves blackspot, and security risk index is not high therefore uses extensive.
The ingredient of ceramide in the present invention be Bai Chihua (LIMNANTHES ALBA) seed oil, Cer NP, glycerol, Phytosphingosine and hydrolecithin, in which: Bai Chihua (LIMNANTHESALBA) seed oil is anti-due to having containing 98% or more The long chain fatty acids of the effect of oxidation, so it is that one of most stable of vegetable oil, white pond flower seed oil can be used as making up in the world Product basis grease, molting hormone has the function of preventing water loss, regeneration skin in white pond flower seed oil, is skin new old generation Thank to activator, it adjusts the exudation of water and compound, reuptake moisture and in epidermal layer cells by changing keratin tissue Hydrate is formed to lock moisture in skin epidermis;Cer NP is a kind of lipid matter, artificial synthesized ingredient, it and structure It is close at the structure of matter of keratoderma, skin can be penetrated into quickly, helps the update of skin natural containment, can be promoted certainly Water in the balance and cuticula of right aquation combines, and forms a kind of reticular structure, moisture is lockked, to skin moisturizing maintenance There is good action, be skin-active ingredient important in cuticula, skin barrier can be enhanced, reconstituted cell forms effective barrier It prevents water loss and reduces the influence of external environment, the especially needed more ceramides of stimulated skin have research table Bright, wiping the product containing ceramide ingredient can be reduced red and swollen and percutaneous water loss, play enhancing skin barrier and help by Damage the effect that skin alleviates drying regime;Glycerol is also known as glycerine, softness, moisturizing, makeup removing solvent and lubricant.Absolutely not directly Using 100% not diluted pure glycerin, minus effect will cause, glycerol has water sorption, and Moisturizer is usually inhaled with it Hydrone in attached air, the keratoderma for enabling it cover keep wet;Phytosphingosine is Phospholipids (Ceramides's) Predecessor, it is more close with skin lipid, it is the important component of water tariff collection and barrier function, phytosphingosine is human epidermal In important one of lubricant component, as the age increases and enter the senescence phase, the phytosphingosine in human skin can subtract gradually It is few, lead to dry skin and coarse skin, exterior-applied plant sphingol, which has, efficiently to be kept skin soft and moist and have the work of protection cortex With;Phytosphingosine has antibiotic property, also there is anti-inflammatory effect, can be used for the prevention and treatment of the dermatopathies such as acne;Hydrolecithin is ovum The partial hydrolystate of phosphatide, hydrolecithin improve its hydrophilic ability, and the skin and hair for people absorb and can promote it The infiltration of his nutriment can be common to conditioning-type cosmetics, lecithin emulsification with linolenic acid, hyaluronic acid, vitamins Effect is strong, and energy stable emulsion is suitable for preparing gel type products.
Glycerin monostearate in the present invention is the ingredient of monoglyceride, is assistant for emulsifying agent.
Cetostearyl alcohol in the present invention is the ingredient of C16/18 alcohol, and cetostearyl alcohol belongs to fatty alcohol, and appearance is white Wax can provide creamy texture, be emollients.
Carbomer in the present invention, i.e. Carbopol 940, belong to high molecular polymer, are thickeners.
Glycerol in the present invention is colourless sweet clear and bright thick liquid, odorless, there is warm sweet taste, can be used as solvent, lubricant, Medicament and sweetener.
C12-13 alcohol phosphate potassium in the present invention, is the ingredient of HR-S1, is emulsifier.
Reed fragrant plant glue in the present invention, main component is polyglycerolmethacrylate, is a kind of water-soluble not dry lubricant, Performance of keeping humidity is excellent, can improve the skin sense and lubricity, good water solubility of product, be transparent moisturizing substrate, has dual guarantor Wet effect, when massage, is easy to and skin absorbs, and improves microcirculation, promotes cell metabolism, adjusts skin ph value, effectively adjusting grease Secretion, pore refining.
Sodium hydroxide in the present invention, i.e. NaOH are PH regulators.
GC-04 in the present invention contains natural fatty acid glyceride, decoyl hydroximic acid and parahydroxyacet-ophenone, wherein sweet Oil and fat acid esters is a kind of active skull cap components being present in human breast milk, can enhance newborn infant diseases and resist and be immunized Power, the mild polarity of skin is good, inhibits bacterium to agree yeast increment activity, also there is moisturizing, emulsification, moisturizing, wetting and Sage Extract And other effects;Parahydroxyacet-ophenone be present in compositae plant artemisia scoparia (Artemisia scoparia Waldst.et kit.) stem, Leaf and the anti-wormwood artemisia of mattress (A.capillaris Thunb.), Luo Mo section plant kerr tylophora root (Tylophora Kerrii It is natural antioxidant in the plants such as root Craib);Decoyl hydroximic acid is a no added preservative, its energy bactericidal, Solubilized hydrotropy.
Essence in the present invention, tarts up to cosmetics.
Sodium Hyaluronate in the present invention, is the main component of hyaluronic acid, and Sodium Hyaluronate is also known as sodium hyaluronate sodium, belongs to flesh Skin conditioner is a kind of acid mucopolysaccharide, is naturally present in cornea skin, itself 1000 times of moisture of weight is can absorb, to reach It is lost to by retaining moisture of skin, prevention moisture through epidermis, and the barrier reparation when skin is damaged, skin is enabled to make Will not feel drying after, increase gloss, it can improve skin-nourishing metabolism, make skin it is soft, it is smooth, go wrinkle, increase elasticity, Aging is prevented, is good skin penetration enhancer again while moisturizing.It is used cooperatively, can play with other nutritional ingredients Promote the more preferable effect of nutrient absorption.
The two of task of the present invention realize by following technical solution:
A kind of preparation method of the above-mentioned moisturizing moisturizer containing ceramide, comprising the following steps:
(1) caprylic/capric triglyceride, isopropyl palmitate, dimethyl silicone polymer, life are weighed by quality proportioning It educates phenol acetic acid esters, ceramide, monoglyceride, cetostearyl alcohol and oily phase pot is added, stir evenly and be heated to 85 DEG C, obtain material A;The carbomer, glycerol, deionized water, reed fragrant plant glue are weighed by quality proportioning to sequentially add water phase pot and stir evenly, and are heated to At 65 DEG C, the C12-13 alcohol phosphate potassium is added, then proceedes to be heated to 85 DEG C, obtains material B;
(2) sodium hydroxide and hyaluronic acid are weighed by quality proportioning, 10% hydrogen-oxygen is respectively prepared by deionized water Change sodium solution and 2% hyaluronic acid solution, then mixing is dissolved into transparent, obtains material C;
(3) material B is pumped into stirring in emulsion pot and is kept for 85 DEG C of temperature, material A is added in emulsion pot by moderate-speed mixer Material C is added after stirring one minute, continues stirring when temperature is down to 75 DEG C, emulsifying 6 minutes, then proceedes to stirring drop Temperature weighs the GC-04, essence and various plants extract by quality proportioning and is added thereto, stir when temperature is down to 40 DEG C It mixes and uniformly obtains the moisturizing moisturizer containing ceramide.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that saying that the specific embodiment of description is used only for explaining the present invention herein, it is not used to Limit the present invention.
Embodiment 1:
A kind of moisturizing moisturizer containing ceramide, is prepared by the component of following quality proportionings:
Caprylic/capric triglyceride: 15%;
Isopropyl palmitate: 2.8%;
Dimethyl silicone polymer: 1.8%;
Tocopherol acetate: 0.5%;
Ceramide: 0.5%;
Glycerin monostearate: 2%;
Cetostearyl alcohol: 2.6%;
Carbomer: 0.128%;
Glycerol: 9%;
C12-13 alcohol phosphate potassium: 3%;
Reed fragrant plant glue: 2%;
Sodium hydroxide: 0.018%;
GC-04:0.5%;
Essence: 0.2%;
Sodium Hyaluronate: 0.05%;
Various plants extract: 2%;
Deionized water: 57.904%.
Embodiment 2:
A kind of moisturizing moisturizer containing ceramide, is prepared by the component of following quality proportionings:
Caprylic/capric triglyceride: 18%;
Isopropyl palmitate: 3.2%;
Dimethyl silicone polymer: 2.1%;
Tocopherol acetate: 1%;
Ceramide: 1%;
Glycerin monostearate: 2.2%;
Cetostearyl alcohol: 2.9%;
Carbomer: 0.132%;
Glycerol: 11%;
C12-13 alcohol phosphate potassium: 3.5%;
Reed fragrant plant glue: 5%;
Sodium hydroxide: 0.02%;
GC-04:1%;
Essence: 0.4%;
Sodium Hyaluronate: 0.1%;
Various plants extract: 3%;
Deionized water: 45.448%.
Embodiment 3:
A kind of moisturizing moisturizer containing ceramide, is prepared by the component of following quality proportionings:
Caprylic/capric triglyceride: 17%;
Isopropyl palmitate: 3%;
Dimethyl silicone polymer: 2%;
Tocopherol acetate: 0.7%;
Ceramide: 0.7%;
Glycerin monostearate: 2.1%;
Cetostearyl alcohol: 2.7%;
Carbomer: 0.13%;
Glycerol: 10%;
C12-13 alcohol phosphate potassium: 3.3%;
Reed fragrant plant glue: 4%;
Sodium hydroxide: 0.019%;
GC-04:0.7%;
Essence: 0.3%;
Sodium Hyaluronate: 0.07%;
Various plants extract: 2.5%;
Deionized water: 50.781%.
In any embodiment, the preparation method of the moisturizing moisturizer containing ceramide, comprising the following steps:
(1) caprylic/capric triglyceride, isopropyl palmitate, dimethyl silicone polymer, life are weighed by quality proportioning It educates phenol acetic acid esters, ceramide, monoglyceride, cetostearyl alcohol and oily phase pot is added, stir evenly and be heated to 85 DEG C, obtain material A;The carbomer, glycerol, deionized water, reed fragrant plant glue are weighed by quality proportioning to sequentially add water phase pot and stir evenly, and are heated to At 65 DEG C, the C12-13 alcohol phosphate potassium is added, then proceedes to be heated to 85 DEG C, obtains material B;
(2) sodium hydroxide and hyaluronic acid are weighed by quality proportioning, 10% hydrogen-oxygen is respectively prepared by deionized water Change sodium solution and 2% hyaluronic acid solution, then mixing is dissolved into transparent, obtains material C;
(3) material B is pumped into stirring in emulsion pot and is kept for 85 DEG C of temperature, material A is added in emulsion pot by moderate-speed mixer Material C is added after stirring one minute, continues stirring when temperature is down to 75 DEG C, emulsifying 6 minutes, then proceedes to stirring drop Temperature weighs the GC-04, essence and various plants extract by quality proportioning and is added thereto, stir when temperature is down to 40 DEG C It mixes and uniformly obtains the moisturizing moisturizer containing ceramide.
The main component of various plants extract in the present invention is lady's bower (CLEMATIS VITALBA) leaf It is sub- in extract, peach (PRUNUS PERSICA) berry extract, hundred golden flower (CENTAURIUM ERYTHRAEA) extract, horse ladder Opium poppy (ROMNEYA COULTERII) flower extract, foreign ivy (HEDERA HELIX) extract and butanediol.Wherein: Portugal Grape leaf clematis (CLEMATIS VITALBA) leaf extract can releive dry and chap of the skin skin, reduce other ingredients to skin Stimulation;Peach berry extract has proliferation function to epidermal keratinocyte, to oxynitrides generate inhibition, furthermore antioxidant and The water content that cuticula can relatively significantly be improved shows that peach extract has good skin-active and anti-ageing type energy, can be used for because of stemness Skin aging caused by skin, actin-myosin are a models of simulated skin corium construction, and peach extract is to it There is contraction, can indicate that it has skin tightening effect;Hundred golden flower extracts are that middle extraction is spent from platinum, and extract mainly contains green original Sour and other functional ingredient has extensive bacteriostasis, can supplement pure moisture for skin, the skin being easily dried of releiving is formed Make healthy skin;Foreign ivy extract is the natural products extracted from foreign ivy, has inhibition to the activity of apolipoprotein, Underarm odor can be reduced, have inhibition to Corynebacterium xerosis, can be used for pressing down it is smelly, play the role of inhibit sebum secretion, be suitable for oil The nursing of property skin.
Caprylic/capric triglyceride in the present invention is the ingredient of GTCC, is that height clearly spends tasteless grease, belongs to palm oil Or the derivative of coconut oil, it is extracted using hot fractional method.Since it and human skin have compatible feature, there is non-greasy matter Sense, its extensibility can be improved by being added in creams or lotion, had lubrication and made the effect of skin softness, and had the function of filtering ultraviolet Can, can make emollients, solvent, permeation enhancers come using.
Isopropyl palmitate in the present invention is the ingredient of IPP, this can increase production at low molecule monoesters class is belonged to Product ductility, tends to smear out and has no greasy feeling, by moisturizing and affected skin can be promoted to restore, eliminate nail fungi, moreover it is possible to pre- Anti- eczema and dermatitis.
Dimethyl silicone polymer in the present invention is the ingredient of DC500, and dimethyl silicone polymer is also known as dimeticone, profit Slip energy is good, can form one layer of uniform protective film with waterproofness after applying skin, but without any sticky and greasy Feeling, glossiness is good;The performance of ultra-violet radiation resisting is good, it under ultraviolet light will not oxidation deterioration and cause to skin irritatin Effect;Antistatic property is good, experiments have shown that, the skin electrostatic for the face cream containing polysiloxanes that nuzzles up all is eliminated, and is had apparent Dust-proof effect;Good permeability, even if forming silicone film on the skin nor affects on sweat discharge;It has flavors and fragrances slow Fixation effect is released, thus protects longer stability height of fragrant phase, it is chemically inert, to other compositions of cosmetics, especially active constituent There is no any adverse effect matching good, it is nontoxic, odorless, tasteless, stimulation and allergy will not be caused to skin, it is highly-safe, it is right Certain skin diseases have certain curative effect, such as sweating difficulty type eczema neurodermatitis and occupational dermatitis.
Tocopherol acetate in the present invention is the ingredient of VE oil, and tocopherol acetate belongs to the derivative of vitamin E, It is used as antioxidant, there is good antioxidant effect, it is to seek well to skin that it, which is a kind of oil-soluble natural materials, Moisturizing agent is supported, makes an addition in skin care products, can be avoided the rancid oxidation of grease, stabilizes grease, in moisturizing and maintains connective tissue, And skin is protected not had fine performance by uv damage, which can make skin soft-touch and keep skin moisture, Promoting wound healing, prevention inflammation prevents the coarse chap of skin, improves blackspot, and security risk index is not high therefore uses extensive.
The ingredient of ceramide in the present invention be Bai Chihua (LIMNANTHES ALBA) seed oil, Cer NP, glycerol, Phytosphingosine and hydrolecithin, in which: Bai Chihua (LIMNANTHESALBA) seed oil is anti-due to having containing 98% or more The long chain fatty acids of the effect of oxidation, so it is that one of most stable of vegetable oil, white pond flower seed oil can be used as making up in the world Product basis grease, molting hormone has the function of preventing water loss, regeneration skin in white pond flower seed oil, is skin new old generation Thank to activator, it adjusts the exudation of water and compound, reuptake moisture and in epidermal layer cells by changing keratin tissue Hydrate is formed to lock moisture in skin epidermis;Cer NP is a kind of lipid matter, artificial synthesized ingredient, it and structure It is close at the structure of matter of keratoderma, skin can be penetrated into quickly, helps the update of skin natural containment, can be promoted certainly Water in the balance and cuticula of right aquation combines, and forms a kind of reticular structure, moisture is lockked, to skin moisturizing maintenance There is good action, be skin-active ingredient important in cuticula, skin barrier can be enhanced, reconstituted cell forms effective barrier It prevents water loss and reduces the influence of external environment, the especially needed more ceramides of stimulated skin have research table Bright, wiping the product containing ceramide ingredient can be reduced red and swollen and percutaneous water loss, play enhancing skin barrier and help by Damage the effect that skin alleviates drying regime;Glycerol is also known as glycerine, softness, moisturizing, makeup removing solvent and lubricant.Absolutely not directly Using 100% not diluted pure glycerin, minus effect will cause, glycerol has water sorption, and Moisturizer is usually inhaled with it Hydrone in attached air, the keratoderma for enabling it cover keep wet;Phytosphingosine is Phospholipids (Ceramides's) Predecessor, it is more close with skin lipid, it is the important component of water tariff collection and barrier function, phytosphingosine is human epidermal In important one of lubricant component, as the age increases and enter the senescence phase, the phytosphingosine in human skin can subtract gradually It is few, lead to dry skin and coarse skin, exterior-applied plant sphingol, which has, efficiently to be kept skin soft and moist and have the work of protection cortex With;Phytosphingosine has antibiotic property, also there is anti-inflammatory effect, can be used for the prevention and treatment of the dermatopathies such as acne;Hydrolecithin is ovum The partial hydrolystate of phosphatide, hydrolecithin improve its hydrophilic ability, and the skin and hair for people absorb and can promote it The infiltration of his nutriment can be common to conditioning-type cosmetics, lecithin emulsification with linolenic acid, hyaluronic acid, vitamins Effect is strong, and energy stable emulsion is suitable for preparing gel type products.
Glycerin monostearate in the present invention is the ingredient of monoglyceride, is assistant for emulsifying agent.
Cetostearyl alcohol in the present invention is the ingredient of C16/18 alcohol, and cetostearyl alcohol belongs to fatty alcohol, and appearance is white Wax can provide creamy texture, be emollients.
Carbomer in the present invention, i.e. Carbopol 940, belong to high molecular polymer, are thickeners.
Glycerol in the present invention is colourless sweet clear and bright thick liquid, odorless, there is warm sweet taste, can be used as solvent, lubricant, Medicament and sweetener.
C12-13 alcohol phosphate potassium in the present invention, is the ingredient of HR-S1, is emulsifier.
Reed fragrant plant glue in the present invention, main component is polyglycerolmethacrylate, is a kind of water-soluble not dry lubricant, Performance of keeping humidity is excellent, can improve the skin sense and lubricity, good water solubility of product, be transparent moisturizing substrate, has dual guarantor Wet effect, when massage, is easy to and skin absorbs, and improves microcirculation, promotes cell metabolism, adjusts skin ph value, effectively adjusting grease Secretion, pore refining.
Sodium hydroxide in the present invention, i.e. NaOH are PH regulators.
GC-04 in the present invention contains natural fatty acid glyceride, decoyl hydroximic acid and parahydroxyacet-ophenone, wherein sweet Oil and fat acid esters is a kind of active skull cap components being present in human breast milk, can enhance newborn infant diseases and resist and be immunized Power, the mild polarity of skin is good, inhibits bacterium to agree yeast increment activity, also there is moisturizing, emulsification, moisturizing, wetting and Sage Extract And other effects;Parahydroxyacet-ophenone be present in compositae plant artemisia scoparia (Artemisia scoparia Waldst.et kit.) stem, Leaf and the anti-wormwood artemisia of mattress (A.capillaris Thunb.), Luo Mo section plant kerr tylophora root (Tylophora Kerrii It is natural antioxidant in the plants such as root Craib);Decoyl hydroximic acid is a no added preservative, its energy bactericidal, Solubilized hydrotropy.
Essence in the present invention, tarts up to cosmetics.
Sodium Hyaluronate in the present invention, is the main component of hyaluronic acid, and Sodium Hyaluronate is also known as sodium hyaluronate sodium, belongs to flesh Skin conditioner is a kind of acid mucopolysaccharide, is naturally present in cornea skin, itself 1000 times of moisture of weight is can absorb, to reach It is lost to by retaining moisture of skin, prevention moisture through epidermis, and the barrier reparation when skin is damaged, skin is enabled to make Will not feel drying after, increase gloss, it can improve skin-nourishing metabolism, make skin it is soft, it is smooth, go wrinkle, increase elasticity, Aging is prevented, is good skin penetration enhancer again while moisturizing.It is used cooperatively, can play with other nutritional ingredients Promote the more preferable effect of nutrient absorption.
Deionized water in the present invention is solvent.
Moisturizing moisturizer of the present invention containing ceramide has prolonged replenishing water and preserving moisture effect, can alleviate dry skin shape State can reinforce skin anti-aging function, and skin is enabled to keep elasticity, smooth careful, reduce the generation of facial wrinkles and to damage Skin has repair.Foreign ivy (the HEDERA in phytosphingosine and various plants extract in ceramide HELIX) extract plays the role of antiallergic anti-inflammatory.
Above description is only embodiments herein and the explanation to institute's application technology principle.Those skilled in the art answer Work as understanding, invention scope involved in the application, however it is not limited to technical solution made of the specific combination of above-mentioned technical characteristic, It should also cover in the case where not departing from the inventive concept simultaneously, carry out any group by above-mentioned technical characteristic or its equivalent feature The other technical solutions closed and formed.Such as features described above and (but being not limited to) disclosed herein have the skill of similar functions Art feature is replaced mutually and the technical solution that is formed.

Claims (3)

1. a kind of moisturizing moisturizer containing ceramide, which is characterized in that be prepared by the component of following quality proportionings:
Caprylic/capric triglyceride: 15-18%;
Isopropyl palmitate: 2.8-3.2%;
Dimethyl silicone polymer: 1.8-2.1%;
Tocopherol acetate: 0.5-1%;
Ceramide: 0.5-1%;
Glycerin monostearate: 2-2.2%;
Cetostearyl alcohol: 2.6-2.9%;
Carbomer: 0.128-0.132%;
Glycerol: 9-11%;
C12-13 alcohol phosphate potassium: 3-3.5%;
Reed fragrant plant glue: 2-5%;
Sodium hydroxide: 0.018-0.02%;
GC-04:0.5-1%;
Essence: 0.2-0.4%;
Sodium Hyaluronate: 0.05-0.1%;
Various plants extract: 2-3%;
Water: 45.448-57.904%;
The ingredient of the ceramide is Bai Chihua (LIMNANTHES ALBA) seed oil, Cer NP, glycerol, phytosphingosine And hydrolecithin;The ingredient of the reed fragrant plant glue is glycerol polymethacrylates, water, glycerol and propylene glycol;A variety of plants The ingredient of object extract is lady's bower (CLEMATIS VITALBA) leaf extract, peach (PRUNUS PERSICA) fruit mentions Sub- opium poppy (ROMNEYA COULTERII) flower in object, hundred golden flower (CENTAURIUM ERYTHRAEA) extract, horse ladder is taken to extract Object, foreign ivy (HEDERA HELIX) extract and butanediol;The ingredient of the GC-04 is decoyl hydroximic acid, glycerol octanoic acid Ester and parahydroxyacet-ophenone.
2. the moisturizing moisturizer containing ceramide according to claim 1, which is characterized in that the water is deionized water.
3. a kind of preparation method based on the moisturizing moisturizer described in claim 1 containing ceramide, which is characterized in that including with Lower step:
(1) caprylic/capric triglyceride, isopropyl palmitate, dimethyl silicone polymer, tocopherol are weighed by quality proportioning Oily phase pot is added in acetic acid esters, ceramide, monoglyceride, cetostearyl alcohol, stirs evenly and is heated to 85 DEG C, obtains material A;It presses Quality proportioning weighs the carbomer, glycerol, deionized water, reed fragrant plant glue and sequentially adds water phase pot and stir evenly, and is heated to 65 DEG C When, the C12-13 alcohol phosphate potassium is added, then proceedes to be heated to 85 DEG C, obtains material B;
(2) sodium hydroxide and hyaluronic acid are weighed by quality proportioning, 10% sodium hydroxide is respectively prepared by deionized water Solution and 2% hyaluronic acid solution, then mixing is dissolved into transparent, obtains material C;
(3) material B is pumped into stirring in emulsion pot and is kept for 85 DEG C of temperature, material A is added in emulsion pot and stirs by moderate-speed mixer Material C is added after one minute, continues stirring when temperature is down to 75 DEG C, emulsifying 6 minutes, then proceedes to stirring cooling, to When temperature is down to 40 DEG C, the GC-04, essence and various plants extract being weighed by quality proportioning and is added thereto, stirring is equal It is even to obtain the moisturizing moisturizer containing ceramide.
CN201811300968.0A 2018-11-02 2018-11-02 A kind of moisturizing moisturizer and preparation method thereof containing ceramide Pending CN109481337A (en)

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CN109865160A (en) * 2019-04-04 2019-06-11 广东华润顺峰药业有限公司 A kind of Liquid crystal compound and preparation method thereof
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CN110123661A (en) * 2019-05-23 2019-08-16 广州科斯曼生物科技有限公司 A kind of anti-inflammatory anti-wrinkle composition of the moisturizing comprising ceramide and its preparation method and application
CN110123661B (en) * 2019-05-23 2021-11-05 广州科斯曼生物科技有限公司 Moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, and preparation method and application thereof
CN110192985A (en) * 2019-06-26 2019-09-03 广州市百爱神生物科技有限公司 A kind of care agent and preparation method thereof for skin moisture-keeping reparation
CN110251417A (en) * 2019-07-12 2019-09-20 广州市科能化妆品科研有限公司 Essence cream and preparation method thereof before oil-control reparation adornment
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CN112641649A (en) * 2020-12-24 2021-04-13 广东丸美生物技术股份有限公司 Moisturizing composition and cosmetic and application thereof
CN112754951A (en) * 2021-02-10 2021-05-07 广州市雅彩盛生物科技有限公司 Cosmetic for repairing skin barrier and preparation method thereof
CN114106214A (en) * 2021-12-06 2022-03-01 山西大同大学 Hemerocallis citrina polysaccharide and preparation method and application thereof
CN115006324A (en) * 2022-06-16 2022-09-06 广东格烯生物科技股份有限公司 Nourishing and repairing lotion containing ceramide NP and preparation method thereof
CN115006324B (en) * 2022-06-16 2023-08-29 广东格烯生物科技股份有限公司 Nourishing and repairing emulsion containing ceramide NP and preparation method thereof

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