CN107156843A - The effect of beneficial liver and its application of purple rice - Google Patents
The effect of beneficial liver and its application of purple rice Download PDFInfo
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- CN107156843A CN107156843A CN201710369041.1A CN201710369041A CN107156843A CN 107156843 A CN107156843 A CN 107156843A CN 201710369041 A CN201710369041 A CN 201710369041A CN 107156843 A CN107156843 A CN 107156843A
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- purple rice
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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Abstract
The invention discloses purposes of the purple rice (purple rice) in beneficial liver effect product is prepared.Using purple rice fruit as raw material, the beneficial liver product of all kinds of high-quality can be effectively converted to by extraction process and processing technology, includes the health-care products and natural drug product of human and animal.
Description
Technical field
The present invention relates to the process technology of the rice varieties " purple rice " acted on beneficial liver and food, health food,
Purposes in natural drug, is fresh dried purple rice, deep processing and method for preparing extractive, purple rice deep processing production specifically
Purposes in liver-protecting efficacy health products are prepared of product, purple rice extract, purple rice active chemical, purple rice, purple rice are preparing liver
Application in scorching medicine.
Background technology
Liver is one of organ important in body, and the working process work of substantial amounts of biochemistry factory is subject daily
Make, the processing being metabolized to the substantial amounts of food absorbed through alimentary canal and other foreign substances, be very easy to fatigue with
Sustain damage.Hepar damnification is the disease for seriously endangering people's health.The hepatitis B that China has more than 100,000,000 people at present is lifelong
Carrier, the carrier of tens million of HCVs, wherein about tens of millions of people can be transformed into chronic hepatitis, hepatic sclerosis, liver cancer,
The people dead because of hepatopathy there are about hundreds of thousands of them every year.It is poisoned in recent years as being addicted to drink, caused by medicine and various adverse factors
Property hepar damnification also increases increasingly.It is Chinese annual for treating the costly up to tens billion of yuans of hepatopathy, to economy and society
The physical and mental health that particularly patient can be developed causes very big burden, so keeping the health of liver turns into the mesh that people pursue
Mark.Food and medicine are to influence the key factor of liver function, thus exploitation be beneficial to the food of liver health, health food and
New drug is just very urgent.
Rice is the important staple food grain of our people.Rice is rice (Oryza sativa L.) fruit (caryopsis),
Referred to as rice, rice or rice.The cultivar of rice is extremely more, there is more than thousands of kinds；Only the fruit colour of rice is just distinguished
For the appearance color such as white, green, yellow, red, purple, black, wherein white rice is the kind of most often to eat.Purple rice (purple rice) is big
Grain of rice fruit crust is the rice of purple, and English is purple rice.In the area of many growth purple rices all without the anti-hepatitis of purple rice
Report.The rice of different colours shows different in its chemical composition, may be in terms of alimentary health-care function
Difference.
The present invention this be found that the new application in edible, food, health food and medicine of purple rice, processing method with
And the active ingredient contained etc..
The content of the invention
It is an object of the invention to provide the new application of purple rice, that is, preparing hepatitis treatment medicine, health food and animal benefit
New opplication in liver product.
It is a further object of the present invention to provide a kind of medicine of hepatitis treatment.
It is also another object of the present invention to provide a kind of health food of hepatitis auxiliary treatment.
The purpose of the present invention also includes providing preparing convenient, health care and the good purple rice extract of therapeutic effect and its preparation side
Method.
Inventor has carried out substantial amounts of deep processing to purple rice according to the processing method of agricultural product and studied, including purple rice rice cake,
Purple rice Lantern Festival (rice dumpling), purple rice Zongzi, purple rice curry, purple rice red bean jelly, purple rice gel, purple rice bean jelly, purple rice drink, purple rice juice vapour
Water, purple rice cola, purple rice tea, purple rice coffee, purple rice vinegar, purple rice rice wine, purple rice liquor, purple rice pure mellow wine, purple rice sweet wine, purple rice beer
Wine, purple rice chrysanthemum wine, purple rice soy sauce, purple rice sauce, purple rice grape wine, purple rice soya-bean milk, purple rice milk, expanded purple rice (puffed rice),
Purple rice sugar, purple rice ground rice, purple rice rice noodles, purple rice saqima, purple rice bread, purple rice hamburger, purple rice cake and biscuit, purple rice ice
River in Henan Province pouring, purple rice thin pancake, purple rice black soya bean meal, purple rice rice dumpling, purple rice raw fish (sushi), purple rice natto meal, purple rice pudding, purple rice egg
The purple mashed potatoes of cake, purple rice mung bean cake, purple rice purple potato meal, purple rice, the purple Chinese yam meal of purple rice, purple rice steamed pork in ground rice, purple rice silkie soup, purple rice
Orychophragmus violaceus congee, purple rice rice bran extract and its processed goods, the specially offered purple rice congee set meal of hepatopathy hospital ward etc..
Inventor's reference《2003 annual drug research technological guidance principle-Chinese medicines, natural goods fascicle》(state food medicine
Product Surveillance Authority 2003),《New drug preclinical study guideline》(national Bureau of Drugs Supervision 1993) and《Health food work(
Assessment process can be learned》The drug evaluation method and health food evaluation method of the hepatitis treatment of (Ministry of Public Health 2003) etc. are right
Purple rice has carried out extract preparation, pharmaceutical dosage form preparation, animal pharmacology and pathological study.
Now, the area of whole nation plantation purple rice is on the increase, and growing area distribution is more and more wider, from Yunnan Guangxi to northeast ground
Qu Douyou is planted, and the purple rice species of in the market is more, and some purple rices have become international geography symbol product.
Inventor has found the effect of the beneficial liver of purple rice.The raw material of various natural products can be made in purple rice.
The preparation method of purple rice extract is：Take purple rice 1000g, add water to cook it is secondary, 10 minutes every time, collecting decoction,
Filtration, filtrate concentration thick paste, continues after drying, fine powder processed is produced.Fine powder can also be spray-dried to obtain.This product is of purple
Grain；Lightly seasoned sweet tea.
Inventor has found, is administered orally with purple rice extract and drug administration by injection, there is obvious effect, serum liver
Biochemical function index and pathological index all improve significantly.
When being treated with purple rice extract, it can be with pulvis, granule, tablet, capsule, pill and liquid preparation etc.
Form is administered orally；Can also be with the form parenteral administration such as parenteral solution, suppository, percutaneous preparation, spray.Purple rice extract
Effective agent, be by with appropriate medicinal blend, such as excipient, adhesive, bleeding agent, lubricant mixing and be configured to
's.
Purple rice extract dosage changes with the age and body weight of the state of an illness, method of administration, patient of patient.It is being administered orally
In the case of, dosage is usually adult 600~1000mg/ days, preferably 800mg/ days.It is also same in health food application aspect
The principle of sample.
It is an advantage of the invention that：The beneficial liver therapeutic action of purple rice is all at home and in the world to find first.Purple rice can be with
It is used as the natural drug for the treatment of hepatitis.
In addition, purple rice preparation method is fairly simple, also comparing thoroughly for the plant growth the characteristic study of crop has certain
The planting base of scale, so the source of material and economy are all secure.The market recognition of natural products is higher, market
Acceptance it is high, good market prospect.
Embodiment
Examples provided below is used for that the present invention is furture elucidated, and is not meant to limit the scope of the invention.
The material of embodiment 1.
We purchase self-control purple rice and rice bran after paddy to purple rice used in embodiment, and purple rice is also directly bought sometimes.It is other
Medicine, reagent and experimental animal, can be easily purchased in market.
The preparation method of embodiment 2. example
(1) purple rice 1000g is taken, added water decoction in 3000ml bags, secondary altogether, 10 minutes every time, and collecting decoction is filtered, filter
Liquid is condensed into thick paste, continues to be concentrated under reduced pressure into dry or is spray-dried, obtains purple powder.
(2) using purple rice as raw material, with aqueous citric acid solution or the ethanol water containing citric acid extracting, purifying and macropore inhale
The liquid purple rice pigment that attached resin is further purified, spray-dried obtained powdery purple rice pigment.
(3) using purple rice chaff as raw material, with light-coloured vinegar solution or the ethanol water containing acetic acid extracting, purifying and macroporous absorption tree
The liquid purple rice pigment that fat is further purified, spray-dried obtained powdery purple rice pigment.It was found that purple rice extract is white
Presented in vinegar based on red, purple is presented in 60 degree of alcohol.
The example of formulations of embodiment 3.
(1) purple rice extract for taking the preparation method of 1kg embodiments 2 to obtain, crushes and crosses 100 mesh sieves, adds appropriate purple
Rice starch or other starch are mixed, and are dispensed after preparing granule, whole grain, every bag of 5g.
(2) the purple rice extract 1000g that the preparation method of Example 2 is obtained, hydroxyethyl cellulose 10g, tabletting is made
Tablet.
(3) purple rice extract that the preparation method of embodiment 2 is obtained is dissolved in physiological saline or isotonic Glucose Liquid, through filtering
Later on demand using the parenteral solution prepared.
(4) purple rice extract that the preparation method of embodiment 2 is obtained is dissolved in water, can be formulated directly into oral liquid.
(5) embodiment 2 preparation method obtain purple rice extract can with eryuelan, Radix Isatidis, the root of Dahurain angelica, leek seed,
The natural drugs such as licorice, which coordinate, is made compound mixture for preventing and treating hepatitis.
The effect experiment of embodiment 4.
(1) evaluation method
The drug efficacy study part of purple rice and its extract for treating hepatitis
We acquire the rice of more than ten kind a variety of colors, have carried out beneficial liver property to different colored rice and variety classes
Experiment.Experimental animal is adult healthy male ICR mouse.Enough running water and normal diet are provided during experiment.Animal
Packet and processing：Mouse is grouped at random by body weight.To be administered for three days on end in the observation of curative effect of hepatitis, once a day.3rd
It carries out hepatitis modeling, and the 4th day of 24 hours takes blood and leave and take animal's liver after modeling, determines the ammonia of liver function enzyme third in serum
Sour transferase (ALT), observes hepatic pathology intensity of variation.Experimental data is represented with mean ± standard deviation.Count soft using EXCEL
Part is analyzed and processed to experimental result using methods such as variance analysis, t inspections, p<0.05 thinks that group difference has conspicuousness.
We have found that have the beneficial liver effect of several purple rices best, and common rice is not observed significantly in this experiment
Beneficial liver effect.(2) evaluation result (table 1, table 2)：Purple rice plays the role of the anti-toxic hepatitis of obvious liver protection.
The effect of the anti-thioacetamide toxic hepatitis of the various purple rices of table 1
Note：##Compared p ﹤ 0.01 with control group.* p ﹤ 0.05 are compared with poisoning hepatitis model group.
The effect of the purple rice of table 2 (Guo before Jilin) anti-carbon tetrachloride poisoning hepatitis
Note：##Compared p ﹤ 0.01 with control group.* p ﹤ 0.05 are compared with poisoning hepatitis model group.
Claims (6)
1. for preparing with the cereal crops product to the beneficial liver effect of human and animal, it is characterised in that contain purple rice or purple rice
Extract.
2. a kind of purple rice extract, it is characterised in that adopt and prepare with the following method, takes purple rice or rice bran, adds water to cook two
Secondary, 10 minutes every time, after drying, fine powder was made in collecting decoction, filtration.
3. purple rice extract according to claim 2, it is characterised in that extract fine powder and appropriate medical dressing are together
A variety of formulations such as oral formulations, injection, granule, tablet, capsule, pill, powder can be made.Can also be with other medicines
Thing or other plant extracts compatibilities composition compound preparation.
4. a kind of medicine for hepatitis auxiliary treatment, it is characterised in that carried containing the purple rice or purple rice described in claim 1 and 2
Take thing.
5. a kind of be used for the health food of beneficial liver, it is characterised in that is extracted containing the purple rice described in claim 1 and 2 or purple rice
Thing.
6. the purple rice or purple rice extract described in purple rice or claim 1 and 2 are preparing the medicine and health products of hepatitis
In application.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710369041.1A CN107156843A (en) | 2017-05-23 | 2017-05-23 | The effect of beneficial liver and its application of purple rice |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710369041.1A CN107156843A (en) | 2017-05-23 | 2017-05-23 | The effect of beneficial liver and its application of purple rice |
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ID=59820407
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| CN201710369041.1A Withdrawn CN107156843A (en) | 2017-05-23 | 2017-05-23 | The effect of beneficial liver and its application of purple rice |
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101874582A (en) * | 2010-05-31 | 2010-11-03 | 周立华 | Method for manufacturing nutritional purple rice chips |
| CN103392989A (en) * | 2013-08-26 | 2013-11-20 | 安徽燕之坊食品有限公司 | Qi-tonifying nutritional porridge and preparation method thereof |
| CN104336250A (en) * | 2014-09-30 | 2015-02-11 | 安徽益方堂生物工程有限公司 | Chrysanthemum tea and preparation method thereof |
| CN105586214A (en) * | 2016-03-16 | 2016-05-18 | 云南农业大学 | Purple rice-purple sweet potato sweet baijiu and preparation method thereof |
| CN105998110A (en) * | 2015-08-19 | 2016-10-12 | 北京健旭康技术有限公司 | Condiment root with liver benefiting effect and application thereof |
| CN105998152A (en) * | 2015-08-19 | 2016-10-12 | 北京健旭康技术有限公司 | Dioscorea opposita Thunb. with liver benefiting effect and application thereof |
| CN106609233A (en) * | 2015-10-26 | 2017-05-03 | 贵州侗之源农耕文化发展有限公司 | Eyesight improving tea aroma black glutinous rice wine |
| CN106605730A (en) * | 2015-10-26 | 2017-05-03 | 贵州侗之源农耕文化发展有限公司 | Poria cocos purple glutinous rice healthy tea |
-
2017
- 2017-05-23 CN CN201710369041.1A patent/CN107156843A/en not_active Withdrawn
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101874582A (en) * | 2010-05-31 | 2010-11-03 | 周立华 | Method for manufacturing nutritional purple rice chips |
| CN103392989A (en) * | 2013-08-26 | 2013-11-20 | 安徽燕之坊食品有限公司 | Qi-tonifying nutritional porridge and preparation method thereof |
| CN104336250A (en) * | 2014-09-30 | 2015-02-11 | 安徽益方堂生物工程有限公司 | Chrysanthemum tea and preparation method thereof |
| CN105998110A (en) * | 2015-08-19 | 2016-10-12 | 北京健旭康技术有限公司 | Condiment root with liver benefiting effect and application thereof |
| CN105998152A (en) * | 2015-08-19 | 2016-10-12 | 北京健旭康技术有限公司 | Dioscorea opposita Thunb. with liver benefiting effect and application thereof |
| CN106609233A (en) * | 2015-10-26 | 2017-05-03 | 贵州侗之源农耕文化发展有限公司 | Eyesight improving tea aroma black glutinous rice wine |
| CN106605730A (en) * | 2015-10-26 | 2017-05-03 | 贵州侗之源农耕文化发展有限公司 | Poria cocos purple glutinous rice healthy tea |
| CN105586214A (en) * | 2016-03-16 | 2016-05-18 | 云南农业大学 | Purple rice-purple sweet potato sweet baijiu and preparation method thereof |
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Application publication date: 20170915 |