CN105998110A - Condiment root with liver benefiting effect and application thereof - Google Patents
Condiment root with liver benefiting effect and application thereof Download PDFInfo
- Publication number
- CN105998110A CN105998110A CN201510510858.7A CN201510510858A CN105998110A CN 105998110 A CN105998110 A CN 105998110A CN 201510510858 A CN201510510858 A CN 201510510858A CN 105998110 A CN105998110 A CN 105998110A
- Authority
- CN
- China
- Prior art keywords
- root
- liver benefiting
- extract
- liver
- radix angelicae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses application of angelica dahurica in preparation of products with liver benefiting effect. The root (liver benefiting root) of umbelliferous plant angelica dahurica is taken as the raw material, and by means of extraction technology and processing technology, the root can be effectively converted into various high-quality liver benefiting products including human and animal health edible products, medicinal diet, natural drug products and medicinal diet products.
Description
Technical field
The present invention relates to an accessory have broad-mouthed receptacle for holding liquid liver effect flavoring agent plant roots process technology and food, health food, natural drug, animal use
Purposes in health product and veterinary drug, specifically, is to be dried the Radix Angelicae Dahuricae (root), deep processing and method for preparing extractive, deep processed product, validation
Study point, the application in the medicine of preparation hepatitis of Radix Angelicae Dahuricae purposes in preparing liver-protecting efficacy health product and medicated diet, the Radix Angelicae Dahuricae and animal the liver benefiting
The application (such as preventing and treating animal hepatitis etc.) of goods.
Background technology
Liver is one of most important Functional tissue in human and animal's body, subjects substantial amounts of biochemistry treatment and processing work every day, right
The substantial amounts of food through digestive tract absorption and feedstuff carry out various processing metabolism, are very easy to fatigue and by various former damages of causing a disease.Liver
Dirty damage is the sick kind of serious harm people's health, and the hepatic injury being currently known is caused a disease and former had thousands of kinds.China has more than the second of 100,000,000 people at present
Hepatovirus lifelong carrier, the carrier of tens million of hepatitis C virus.In recent years by being addicted to drink, medicine and various harmful factor and the toxic that causes
Hepar damnification increases the most increasingly.In hepatopath, tens of millions of people can be transformed into chronic hepatitis, liver cirrhosis, hepatocarcinoma, and because of hepatopathy, the people of death is about every year
There is hundreds of thousands of them.The annual expense for treating hepatopathy of China is up to tens billion of yuans, is good for the body and mind of economy and social development particularly patient
Health causes the biggest burden, so keeping the health of liver to become the target that people pursue.Food is the key factor affecting liver function, so
Exploitation is of value to the food of liver health and medicated diet, health food and new drug are the most urgent.
This product is umbellate form section plant Radix Angelicae Dahuricae Angelica dahurica (Fisch.ex Hoffm.) Benth.et Hook.f. or Radix angelicae dahuricae Angelica dahurica
The dry root of (Fisch.ex Hoffm.) Benth.et Hook.f.var.formosana (Boiss.) Shan et Yuan.Excavate when summer, leaf Huang in autumn, remove
Fibrous root and silt, cut sheet, dries or cold drying.Owing to Radix Angelicae Dahuricae root is also referred to as the Radix Angelicae Dahuricae, and we have found that there is hepatoprotective effect, so
Also referred to as the liver benefiting root.
The Radix Angelicae Dahuricae is a kind of traditional medicine-food two-purpose material.The present invention is found that the Radix Angelicae Dahuricae is in edible, food, health food, medicated diet and medicine just
Protect the liver new application, processing method and the effective ingredient etc. contained.
Summary of the invention
It is an object of the invention to provide the new application of the Radix Angelicae Dahuricae, i.e. new opplication in preparing treating hepatitis medicine, health food and animal the liver benefiting product.
It is a further object of the present invention to provide the natural drug of a kind for the treatment of hepatitis.
It is also another object of the present invention to provide a kind of hepatitis axle and help the health food for the treatment of.
The purpose of the present invention also includes providing prepares good Radix Angelicae Dahuricae extract of convenience, health care and therapeutic effect and preparation method thereof.
Inventor has carried out substantial amounts of deep processing research to Radix Angelicae Dahuricae herb and each position, including angelica dahurica decoction pieces, in vain according to the processing method of Chinese crude drug
Root of Dahurian angelica powder, Radix Angelicae Dahuricae wine, Radix Angelicae Dahuricae meat soup, the Radix Angelicae Dahuricae flu medicated diet soup, Radix Angelicae Dahuricae liver toxin expelling medicated diet soup, Radix Angelicae Dahuricae extract etc..
The Radix Angelicae Dahuricae mainly with the form of decoction pieces and dry powder for the flavor adjuvant of food, the such as powder flavorant such as five spice powder class, SHISANXIANG class contains more
There is Radix Angelicae Dahuricae powder.
Inventor is with reference to " 2003 annual drug research technological guidance principle-Chinese medicine, natural goods fascicle " (State Food and Drug Administration 2003
Year), " new drug preclinical study guideline " (country Bureau of Drugs Supervision 1993) and " function of health food assessment process " (Ministry of Public Health 2003)
Deng the drug evaluation method for the treatment of hepatitis and health food evaluation methodology, the Radix Angelicae Dahuricae has been carried out that prepared by extract, prepared by pharmaceutical dosage form, animal drugs
Reason and pathological study.
The preparation method of Radix Angelicae Dahuricae extract is: can take Radix Angelicae Dahuricae sheet 1000g, does not pulverize or pulverize, boiling three times, each 15 minutes, closes
And decocting liquid, filtering, filtrate concentrates thick paste, continues dried, and fine powder processed to obtain final product.This product is the granule of brown, savory；Bitter in the mouth.
Inventor finds, carries out oral administration and drug administration by injection with Radix Angelicae Dahuricae extract, has an obvious effect, serum liver biochemical function index and
Pathological index all improves significantly.
When treating with Radix Angelicae Dahuricae extract, it can be with form oral administrations such as powder, granule, tablet, capsule, pill and liquid preparations；
Can also be with form parenteral administration such as injection, suppository, percutaneous preparation, sprays.The effective agent of Radix Angelicae Dahuricae extract, by with suitable
Medicinal blend, is configured to such as mixing such as excipient, binding agent, penetrating agent, lubricants.
Radix Angelicae Dahuricae extract dosage changed with route of administration, the age of patient and body weight.In the case of oral administration, dosage is usually adult
400～800mg/ days, preferably 400mg/ days.It also it is same principle in terms of health food and food applications.
The liver benefiting therapeutical effect that the invention have the advantage that the Radix Angelicae Dahuricae is to find first at home and the most all.The Radix Angelicae Dahuricae can be as the sky for the treatment of hepatitis
So medicine.
It addition, Radix Angelicae Dahuricae preparation method is fairly simple, also comparing of plant growing the characteristic study is thorough, there has also been the plantation of certain scale, so material
Source and the economy of material are the most secure.The market recognition of natural product is higher, and the acceptance in market is high, good market prospects.
Detailed description of the invention
Examples provided below is used for being further elucidated with the present invention, and is not meant to limit the scope of the invention.
Embodiment 1. material
Angelica dahurica decoction pieces used by embodiment is pharmacy or regular raw-food material supplier purchase.
Other medicine, reagent and laboratory animal, can be the most commercial.
Embodiment 2. preparation method example
Taking angelica dahurica decoction pieces 1000g, the 2500ml that adds water decocts, totally three times, each 15 minutes, collecting decoction, filters, and filtrate is condensed into thick paste,
Continue to be evaporated to do, obtain brown ceramic powder.
Embodiment 3. example of formulations,
(1) preparation method taking 1kg embodiment 2 obtains the Radix Angelicae Dahuricae extract of each plant parts, pulverizes and crosses 100 mesh sieves, adds appropriate shallow lake
Powder mixes, and prepares granule, carries out subpackage, every bag of 2g after granulate.
(2) Radix Angelicae Dahuricae extract 1000g, the hydroxyethyl cellulose 10g that the preparation method of Example 2 obtains, tablet made by tabletting.
(3) Radix Angelicae Dahuricae extract that the preparation method of embodiment 2 obtains is dissolved in normal saline or isotonic Glucose Liquid, uses on demand after filtered
The injection of preparation.
(4) Radix Angelicae Dahuricae extract that the preparation method of embodiment 2 obtains is dissolved in water, can be formulated directly into oral liquid.
(5) Radix Angelicae Dahuricae extract that the preparation method of embodiment 2 obtains can coordinate with the medicine such as Radix Glycyrrhizae extract, eryuelan extract and makes compound recipe
Mixture is used for preventing and treating hepatitis.
(6) the Radix Angelicae Dahuricae extract powder that the preparation method of embodiment 2 obtains mixes with other seasoning powder, can be formulated directly into compounding medicated diet soup
Material.
Embodiment 4. eating effect is tested
(1) evaluation methodology
The drug efficacy study part of Radix Angelicae Dahuricae extract treatment hepatitis
Laboratory animal is adult healthy male CD-1 mice.Enough tap waters and normal diet are provided during test.Mice is divided at random by body weight
Group.For to be administered for three days on end in the observation of curative effect of toxic hepatitis, once a day.Within 4th day, take blood and leave and take animal livers, measuring in serum
Liver function enzyme alanine transaminase (ALT), observes hepatic pathology intensity of variation.Experimental data represents with mean ± standard deviation.Application EXCEL statistics
Experimental result is used the methods analyst such as variance analysis, t inspection to process by software, and p ＜ 0.05 thinks that group difference has significance.
(2) evaluation result (Tables 1 and 2): the Radix Angelicae Dahuricae has the liver benefiting liver effect of significant anti-toxic hepatitis.
The effect of table 1 Radix Angelicae Dahuricae extract anti-acetaminophen toxic hepatitis
Note:##P ＜ 0.01 is compared with matched group.* compares p ＜ 0.01 with toxic hepatitis group.
Table 2 Radix Angelicae Dahuricae anti-mouse dimethylformamide acute toxic hepatitis effect
Note:#P ＜ 0.05 is compared with matched group.*, * * compares p ＜ 0.05, p ＜ 0.01 with poisoning hepatitis group.
Claims (7)
1. for preparation, human and animal is had the plant product of the liver benefiting effect, it is characterised in that containing the Radix Angelicae Dahuricae (also referred to as the liver benefiting root) or its extract.
2. a liver benefiting root extract, it is characterised in that adopt and prepare with the following method, takes the liver benefiting root, pulverizes or does not pulverizes, boiling three times,
Each 15 minutes, collecting decoction, filter, filtrate concentrates thick paste.Or thick paste is dried, prepare fine powder.
The liver benefiting root extract the most according to claim 3, its feature can make oral system together with extract fine powder and suitable medical dressing
The multiple dosage forms such as agent, injection, granule, tablet, capsule, pill, powder.Can also be with other medicines or other plant extract
Compatibility composition compound preparation.
4. the medicine for hepatitis preventing and treating, it is characterised in that containing the liver benefiting root described in claim 1 and 2 or extract.
5. the health product for the liver benefiting, it is characterised in that containing the liver benefiting root described in claim 1 and 2 or extract.
6. the liver benefiting root or the liver benefiting root described in claim 1 and 2 or extract application in the medicine and health product of preparation hepatitis.
7. the liver benefiting root or the liver benefiting root described in claim 1 and 2 or extract application in preparing medicated diet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510510858.7A CN105998110A (en) | 2015-08-19 | 2015-08-19 | Condiment root with liver benefiting effect and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510510858.7A CN105998110A (en) | 2015-08-19 | 2015-08-19 | Condiment root with liver benefiting effect and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105998110A true CN105998110A (en) | 2016-10-12 |
Family
ID=57082581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510510858.7A Withdrawn CN105998110A (en) | 2015-08-19 | 2015-08-19 | Condiment root with liver benefiting effect and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105998110A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156843A (en) * | 2017-05-23 | 2017-09-15 | 北京健旭康技术有限公司 | The effect of beneficial liver and its application of purple rice |
| CN107496476A (en) * | 2017-09-29 | 2017-12-22 | 北京健旭康技术有限公司 | The beneficial liver effect of yunna cowparsnip and application technology |
| CN107496485A (en) * | 2017-09-29 | 2017-12-22 | 北京健旭康技术有限公司 | The beneficial liver effect of pilose gerbera herb and application technology |
| CN107536891A (en) * | 2017-09-29 | 2018-01-05 | 北京健旭康技术有限公司 | The beneficial liver effect of boenninghausenia sessilicarpa and application technology |
-
2015
- 2015-08-19 CN CN201510510858.7A patent/CN105998110A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 陈广垠编著: "《降脂就这么简单》", 31 August 2014, 安徽科学技术出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156843A (en) * | 2017-05-23 | 2017-09-15 | 北京健旭康技术有限公司 | The effect of beneficial liver and its application of purple rice |
| CN107496476A (en) * | 2017-09-29 | 2017-12-22 | 北京健旭康技术有限公司 | The beneficial liver effect of yunna cowparsnip and application technology |
| CN107496485A (en) * | 2017-09-29 | 2017-12-22 | 北京健旭康技术有限公司 | The beneficial liver effect of pilose gerbera herb and application technology |
| CN107536891A (en) * | 2017-09-29 | 2018-01-05 | 北京健旭康技术有限公司 | The beneficial liver effect of boenninghausenia sessilicarpa and application technology |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105998110A (en) | Condiment root with liver benefiting effect and application thereof | |
| CN103830301A (en) | Flos chrysanthemi with liver tonifying function and application thereof | |
| CN106727872A (en) | The beneficial liver effect of poinsettia and application technology | |
| CN103830374B (en) | The application in hyperuricemia clearly of three leaf glycolipids | |
| CN107890528B (en) | Traditional Chinese medicine composition for treating hyperuricemia and preparation method thereof | |
| CN104095905A (en) | Leguminosae plant with liver-tonifying effect and application thereof | |
| CN107050090A (en) | The effect of beneficial liver and its application of high mountain horseradish dish | |
| CN104306934B (en) | A kind of pharmaceutical composition with strengthen immunity and preparation method thereof | |
| CN108498769A (en) | A kind of medicinal liquor and the preparation method and application thereof | |
| CN104367673B (en) | A kind of Chinese medicine composition treating Eimeria species | |
| CN105998564A (en) | Allium plant with liver benefiting function and application thereof | |
| CN102813713A (en) | Rhizoma dryopteris crassirhizomae and fructus crataegi composition, preparation method and application of composition | |
| CN102579869A (en) | Preparation method of traditional Tibetan medicine composition for treating liver diseases | |
| CN107496485A (en) | The beneficial liver effect of pilose gerbera herb and application technology | |
| CN105998353A (en) | Potato with liver benefiting effect and application thereof | |
| CN105664102A (en) | Traditional Chinese medicine composition for improving immunity | |
| CN106138648A (en) | The liver benefiting effect of head and application thereof | |
| CN107496476A (en) | The beneficial liver effect of yunna cowparsnip and application technology | |
| CN105998152A (en) | Dioscorea opposita Thunb. with liver benefiting effect and application thereof | |
| CN100486621C (en) | Chinese medicinal composition for treating hemilateral headache and its preparation method | |
| CN106138647A (en) | The liver benefiting effect of Folium Allii tuberosi and application thereof | |
| CN103655666B (en) | A kind of plant with beneficial liver effect and application thereof | |
| CN103285110B (en) | Traditional Chinese medicine for treating hyperlipidemia and preparation method thereof | |
| CN105998565A (en) | Liver benefiting effect of allium fistulosum seeds and allium cepa seeds and application thereof | |
| CN107536891A (en) | The beneficial liver effect of boenninghausenia sessilicarpa and application technology |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20161012 |