CN106939049A - 拮抗抑制人pd‑1抗原与其配体结合的单克隆抗体及其制备方法与应用 - Google Patents
拮抗抑制人pd‑1抗原与其配体结合的单克隆抗体及其制备方法与应用 Download PDFInfo
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Abstract
Description
Claims (12)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
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CN201710262053.4A CN106939049B (zh) | 2017-04-20 | 2017-04-20 | 拮抗抑制人pd-1抗原与其配体结合的单克隆抗体及其制备方法与应用 |
EP17906230.2A EP3613768B1 (en) | 2017-04-20 | 2017-06-21 | Monoclonal antibody antagonizing and inhibiting binding between human pd-1 antigen and ligand thereof, preparation method therefor and application thereof |
HRP20240102TT HRP20240102T1 (hr) | 2017-04-20 | 2017-06-21 | Monoklonsko protutijelo koje antagonizira i inhibira vezanje između humanog pd-1 antigena i njegovog liganda, postupak njegove priprave i primjena |
RS20231241A RS64987B1 (sr) | 2017-04-20 | 2017-06-21 | Monoklonsko antitelo koje antagonizuje i inhibira vezivanje humanog pd-1 antigena za njegov ligand, metoda njegovog pripremanja i njegova primena |
US16/606,779 US11345754B2 (en) | 2017-04-20 | 2017-06-21 | Monoclonal antibody antagonizing and inhibiting the binding of human PD-1 antigen to its ligand, preparation method therefor and application thereof |
JP2019556961A JP6928971B2 (ja) | 2017-04-20 | 2017-06-21 | ヒトpd−1抗原とそのリガンドの結合を拮抗・阻害するモノクローナル抗体およびその製造方法と使用 |
PCT/CN2017/089282 WO2018192089A1 (zh) | 2017-04-20 | 2017-06-21 | 拮抗抑制人pd-1抗原与其配体结合的单克隆抗体及其制备方法与应用 |
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CN201710262053.4A CN106939049B (zh) | 2017-04-20 | 2017-04-20 | 拮抗抑制人pd-1抗原与其配体结合的单克隆抗体及其制备方法与应用 |
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US (1) | US11345754B2 (zh) |
EP (1) | EP3613768B1 (zh) |
JP (1) | JP6928971B2 (zh) |
CN (1) | CN106939049B (zh) |
HR (1) | HRP20240102T1 (zh) |
RS (1) | RS64987B1 (zh) |
WO (1) | WO2018192089A1 (zh) |
Cited By (5)
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CN108299561A (zh) * | 2018-01-02 | 2018-07-20 | 暨南大学 | 一种pd-1纳米抗体及其克隆表达方法与应用 |
CN110878122A (zh) * | 2018-09-06 | 2020-03-13 | 上海张江生物技术有限公司 | 重组抗pd-l1单克隆抗体 |
CN113330113A (zh) * | 2018-12-10 | 2021-08-31 | 蓝鸟生物公司 | Pdcd-1归巢核酸内切酶变体 |
CN113563470A (zh) * | 2020-04-29 | 2021-10-29 | 广州昂科免疫生物技术有限公司 | 结合tigit抗原的抗体及其制备方法与应用 |
US11912746B2 (en) | 2016-09-08 | 2024-02-27 | 2Seventy Bio, Inc. | PD-1 homing endonuclease variants, compositions, and methods of use |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108997497B (zh) | 2018-03-30 | 2022-02-25 | 华兰基因工程有限公司 | 特异结合人质膜膜泡关联蛋白pv-1的单克隆抗体及其制备方法与应用 |
KR20220030956A (ko) | 2019-07-05 | 2022-03-11 | 오노 야꾸힝 고교 가부시키가이샤 | Pd-1/cd3 이중 특이성 단백질에 의한 혈액암 치료 |
WO2021025140A1 (ja) | 2019-08-08 | 2021-02-11 | 小野薬品工業株式会社 | 二重特異性タンパク質 |
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CN104560884A (zh) * | 2013-10-25 | 2015-04-29 | 苏州思坦维生物技术有限责任公司 | 拮抗抑制程序性死亡受体pd-1与其配体结合的单克隆抗体及分泌它的杂交瘤细胞系与用途 |
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- 2017-06-21 WO PCT/CN2017/089282 patent/WO2018192089A1/zh active Application Filing
- 2017-06-21 RS RS20231241A patent/RS64987B1/sr unknown
- 2017-06-21 US US16/606,779 patent/US11345754B2/en active Active
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CN113563470A (zh) * | 2020-04-29 | 2021-10-29 | 广州昂科免疫生物技术有限公司 | 结合tigit抗原的抗体及其制备方法与应用 |
CN113563470B (zh) * | 2020-04-29 | 2023-02-10 | 广州昂科免疫生物技术有限公司 | 结合tigit抗原的抗体及其制备方法与应用 |
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Publication number | Publication date |
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CN106939049B (zh) | 2019-10-01 |
HRP20240102T1 (hr) | 2024-03-29 |
US11345754B2 (en) | 2022-05-31 |
JP2020517264A (ja) | 2020-06-18 |
EP3613768B1 (en) | 2023-11-22 |
RS64987B1 (sr) | 2024-01-31 |
EP3613768A4 (en) | 2020-06-17 |
JP6928971B2 (ja) | 2021-09-01 |
EP3613768C0 (en) | 2023-11-22 |
EP3613768A1 (en) | 2020-02-26 |
US20200277376A1 (en) | 2020-09-03 |
WO2018192089A1 (zh) | 2018-10-25 |
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Address after: Suzhou City, Jiangsu province 215100 Xinghu road Suzhou Industrial Park No. 218 BioBAY building C11 Room 201 Applicant after: SUZHOU STAINWEI BIOTECH Inc. Address before: Xinghu road Suzhou Industrial Park in Suzhou city of Jiangsu province Wuzhong District 215100 BioBAY No. 218 building C11 Room 201 Applicant before: SUZHOU STAINWEI BIOTECH Inc. |
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Effective date of registration: 20191223 Address after: No.1-1, Huanghe Road, Pingyuan demonstration area, Xinxiang City, Henan Province Patentee after: HUALAN GENETIC ENGINEERING Co.,Ltd. Address before: 215100 Room 201, C11 building, biological nano Park, No. 218 Xing Hu Road, Suzhou Industrial Park, Suzhou, Jiangsu. Patentee before: SUZHOU STAINWEI BIOTECH Inc. |
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Effective date of registration: 20211115 Address after: 215000 Room 201, C11 floor, bio nano Park, 218 Xinghu street, Suzhou Industrial Park, Jiangsu Province Patentee after: SUZHOU STAINWEI BIOTECH Inc. Address before: 453000 No. 1-1, Huanghe Road, Pingyuan demonstration area, Xinxiang City, Henan Province Patentee before: HUALAN GENETIC ENGINEERING Co.,Ltd. |
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Effective date of registration: 20230321 Address after: 211122 117, 1st Floor, Innovation Center, No. 6, Qiande Road, Jiangning District, Nanjing City, Jiangsu Province (Gaoxin Park) Patentee after: Nanjing Ongke Immune Biopharmaceutical Co.,Ltd. Address before: 215000 Room 201, C11 floor, bio nano Park, 218 Xinghu street, Suzhou Industrial Park, Jiangsu Province Patentee before: SUZHOU STAINWEI BIOTECH Inc. |