CN106421105A - Traditional Chinese medicine preparation for treating diabetes and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating diabetes and preparation method thereof Download PDFInfo
- Publication number
- CN106421105A CN106421105A CN201611217269.0A CN201611217269A CN106421105A CN 106421105 A CN106421105 A CN 106421105A CN 201611217269 A CN201611217269 A CN 201611217269A CN 106421105 A CN106421105 A CN 106421105A
- Authority
- CN
- China
- Prior art keywords
- extract
- chinese medicine
- preparation
- medicine preparation
- radix rehmanniae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine preparation for treating diabetes and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following components in parts by weight: 25 to 75 parts of fresh rehmannia root extract, 25 to 50 parts of figwort root extract, 330 to 380 parts of filler, and 0 to 20 parts of lubricating agent. The preparation method of the traditional Chinese medicine preparation for treating the diabetes comprises the following steps of 1, respectively slicing fresh rehmannia root and figwort root according to the proportion; respectively decocting, and adding 5 to 10 times of water for decocting for 2 to 3 times, wherein the time for decocting of each time is 0.5 to 2 hours; then combining decocting solutions, filtering, concentrating to obtain a thick paste, drying under reduced pressure, and smashing to obtain dry extract powder which is respectively the fresh rehmannia root extract and the figwort root extract; smashing the filler and the lubricating agent, sieving the fresh rehmannia root extract and the figwort root extract through a 80 to 120-mesh sieve, and then mixing the four raw materials according to the proportion; adding the mixture into a particle machine for smashing and mixing; preparing the mixture to be the preparation, inspecting a finished product of the preparation, and packaging. The traditional Chinese medicine preparation provided by the invention has a better and more obvious hypoglycemic effect without side effects of Western medicine.
Description
Technical field
The present invention relates to the technical field of Chinese medicine preparation；Especially a kind of Chinese medicine preparation for treating diabetes and its system
Preparation Method.
Background technology
Diabetes are a kind of common incretion metabolism diseases, and sickness rate is had a strong impact on people and is good in ascendant trend year by year
The lifelong disease of health and life, in China, onset diabetes rate rises for nearly 10 years year by year, increases more than 100 ten thousand every year on average；In
Medical science thinks, the morbidity of diabetes will be deficiency of qi and blood in spleen network, and phlegm-blood stasis stagnate stasis blocking in spleen network, and that causes spleen transfers function
Not normal, so as to cause nutrient metabolism disorder, blood glucose rise, the preventing and treating for actively developing diabetes and its complication has become mesh
The focus of front medical circle research；Chinese medicine prevention diabetes have long history, through the clinical practice of thousands of years, accumulate
Abundant medical experience, and theoretical system and the Therapeutic Method of system is defined, clinically, diabetic is often accompanied by the heart
The abnormal condition such as the disease of the aspects such as blood vessel, such as blood pressure, blood ester, vision, nerve, muscle, skin.Chinese medicine Western medicine so far
Also do not effect a radical cure its good medicine, Western medicine still based on oral antidiabetic drug and insulin injection, large side effects, curative effect is not enough satisfied with.
Content of the invention
For solving to be apt to above-mentioned technical problem, the present invention provides a kind of Chinese medicine preparation for treating diabetes and preparation method, tool
There is quick reduction blood glucose, hypoglycemic effect more preferably becomes apparent from, and the side effect of no Western medicine obtains effect.
The technical solution adopted in the present invention is as follows：
The invention provides a kind of Chinese medicine preparation for treating diabetes, it is characterised in that including the component of following weight portion：Freshly
Yellow extract 25-75 part, Radix Scrophulariae extract 25-50 part, filler 330-380 part, lubricant 0-20 part.
Further, the filler be starch, Lactose, sucrose, Hypromellose, Icing Sugar, dextrin, pregelatinated form sediment
One or more in powder, sorbitol, Mannitol, calcium sulfate, Calcium Carbonate.
Further, the lubricant be magnesium stearate, micropowder silica gel, one or more in Pulvis Talci.
Preferably, the Chinese medicine system of the treatment diabetes is consisted of：Radix Rehmanniae extract 75g, Radix Scrophulariae extract
25g, adjuvant 355g, lubricant 10g, adjuvant contained therein is：Starch 185g, calcium sulfate 170g；Lubricant is magnesium stearate.
Further, described Chinese medicine preparation makes capsule.
Present invention also offers a kind of preparation method of the Chinese medicine preparation for treating diabetes：
1) Radix Rehmanniae, appropriate Radix Scrophulariae are taken respectively, the thin slice of 0.5cm or so is cut into, is boiled respectively, plus 5～10 times amount decoctings boil 2～
3 times, 0.5～2 hour every time, then will decoct water collecting decoction several times, filtration, relative density is concentrated into for 1.30～1.35
The thick paste of (60 DEG C), drying under reduced pressure, crush, dry extract is obtained, is as Radix Rehmanniae extract, Radix Scrophulariae extract.
2) filler is crushed to mean diameter with lubricant super micron mill<50 μm, the Radix Rehmanniae is carried
Take thing, Radix Scrophulariae extract respectively cross 80-120 mesh sieve, be subsequently filled agent, lubricant, Radix Rehmanniae extract, Radix Scrophulariae extract by than
Mixture is after example mixing；
3) mixture is added in Wet mixed granulating machine, mixing speed 500r/min is set, 1000 r/min of speed is shredded, mix
Close 8 min；
4) mixture is made preparation, finished product detection is carried out to preparation, packed after finished product detection is qualified.
Beneficial effects of the present invention：
The present invention has supplementing QI and nourishing YIN, promoting the production of body fluid to quench thirst, can improve xerostomia, constipation, the clinical symptoms such as weak, significantly reduces blood glucose water
The content of gentle glycolated hemoglobin, improves carbohydrate tolerance to a certain extent, promotes Islet Cells Insulin secretion, not acute
Intoxicating is acted on, and can quickly reduce blood glucose, and hypoglycemic effect more preferably becomes apparent from, and the side effect of no Western medicine.
Specific embodiment：
Embodiment 1
A kind of Chinese medicine preparation for treating diabetes, including the raw material of following weight portion：
Radix Rehmanniae extract：50g, Radix Scrophulariae extract：50g, starch：200g, calcium sulfate：180g, magnesium stearate：20g.
Present invention also offers a kind of preparation method of the Chinese medicine preparation for treating diabetes：
1) Radix Rehmanniae, appropriate Radix Scrophulariae are taken respectively, the thin slice of 0.5cm or so is cut into, is boiled respectively, plus 5～10 times amount decoctings boil 2～
3 times, 0.5～2 hour every time, then will decoct water collecting decoction several times, filtration, relative density is concentrated into for 1.30～1.35
The thick paste of (60 DEG C), drying under reduced pressure, crush, obtain dry extract, as Radix Rehmanniae extract, Radix Scrophulariae extract.
2) filler is crushed to mean diameter with lubricant super micron mill<50 μm, the Radix Rehmanniae is carried
Take thing, Radix Scrophulariae extract and 80-120 mesh sieve is crossed, be subsequently filled agent, lubricant, Radix Rehmanniae extract, Radix Scrophulariae extract and mix in proportion
Mixture is after conjunction；
3) Radix Rehmanniae extract, Radix Scrophulariae extract, filler and lubricant are weighed mixture, adds to Wet mixed granulating machine
In, mixing speed 500r/min is set, 1000 r/min of speed is shredded, mix 8 min；
4) mixture is made preparation, by the loading amount filling 1 of 0.5 ± 10%g/ grain#Capsule shells；
5) finished product detection is carried out to capsule, is packed after finished product detection is qualified.During packaging, using medicinal high density polyethylene (HDPE)
Plastic bottle, is sealed with aluminum plastic film, interior plus silica-gel desiccant, is packed by 50/bottle or 100/bottle specifications.
Embodiment 2
A kind of Chinese medicine preparation for treating diabetes, including following raw material：Radix Rehmanniae extract 25g, Radix Scrophulariae extract：
50g, starch：170g, calcium sulfate：160g
Present invention also offers a kind of preparation method of the Chinese medicine preparation for treating diabetes：
1) Radix Rehmanniae, appropriate Radix Scrophulariae are taken respectively, the thin slice of 0.5cm or so is cut into, is boiled respectively, plus 5～10 times amount decoctings boil 2～
3 times, 0.5～2 hour every time, then will decoct water collecting decoction several times, filtration, relative density is concentrated into for 1.30～1.35
The thick paste of (60 DEG C), drying under reduced pressure, crush, obtain dry extract, as Radix Rehmanniae extract, Radix Scrophulariae extract.
2) filler is crushed to mean diameter with lubricant super micron mill<50 μm, the Radix Rehmanniae is carried
Take thing, Radix Scrophulariae extract and 80-120 mesh sieve is crossed, be subsequently filled agent, lubricant, Radix Rehmanniae extract, Radix Scrophulariae extract and mix in proportion
Mixture is after conjunction；
3) Radix Rehmanniae extract, Radix Scrophulariae extract, filler and lubricant are weighed mixture, adds to Wet mixed granulating machine
In, mixing speed 500r/min is set, 1000 r/min of speed is shredded, mix 8 min；
4) mixture is made preparation, by the loading amount filling 1 of 0.5 ± 10%g/ grain#Capsule shells；
5) finished product detection is carried out to capsule, is packed after finished product detection is qualified.During packaging, using medicinal high density polyethylene (HDPE)
Plastic bottle, is sealed with aluminum plastic film, interior plus silica-gel desiccant, is packed by 50/bottle or 100/bottle specifications.
Embodiment 3
A kind of Chinese medicine preparation for treating diabetes, including following raw material：Radix Rehmanniae extract 75g, Radix Scrophulariae extract
25g, starch 185g, calcium sulfate 170g, magnesium stearate 10g.
Present invention also offers a kind of preparation method of the Chinese medicine preparation for treating diabetes：
1) Radix Rehmanniae, appropriate Radix Scrophulariae are taken respectively, the thin slice of 0.5cm or so is cut into, is boiled respectively, plus 5～10 times amount decoctings boil 2～
3 times, 0.5～2 hour every time, then will decoct water collecting decoction several times, filtration, relative density is concentrated into for 1.30～1.35
The thick paste of (60 DEG C), drying under reduced pressure, crush, obtain dry extract, as Radix Rehmanniae extract, Radix Scrophulariae extract.
2) filler is crushed to mean diameter with lubricant super micron mill<50 μm, the Radix Rehmanniae is carried
Take thing, Radix Scrophulariae extract and 80-120 mesh sieve is crossed, be subsequently filled agent, lubricant, Radix Rehmanniae extract, Radix Scrophulariae extract and mix in proportion
Mixture is after conjunction；
3) Radix Rehmanniae extract, Radix Scrophulariae extract, filler and lubricant are weighed mixture, adds to Wet mixed granulating machine
In, mixing speed 500r/min is set, 1000 r/min of speed is shredded, mix 8 min；
4) mixture is made preparation, by the loading amount filling 1 of 0.5 ± 10%g/ grain#Capsule shells；
5) finished product detection is carried out to capsule, is packed after finished product detection is qualified.During packaging, using medicinal high density polyethylene (HDPE)
Plastic bottle, is sealed with aluminum plastic film, interior plus silica-gel desiccant, is packed by 50/bottle or 100/bottle specifications.
Embodiment 4
A kind of Chinese medicine preparation for treating diabetes, including following raw material：Radix Rehmanniae extract 50g, Radix Scrophulariae extract 35,
Starch 185g, calcium sulfate 170g, magnesium stearate 10g.
Present invention also offers a kind of preparation method of the Chinese medicine preparation for treating diabetes：
1) Radix Rehmanniae, appropriate Radix Scrophulariae are taken respectively, the thin slice of 0.5cm or so is cut into, is boiled respectively, plus 5～10 times amount decoctings boil 2～
3 times, 0.5～2 hour every time, then will decoct water collecting decoction several times, filtration, relative density is concentrated into for 1.30～1.35
The thick paste of (60 DEG C), drying under reduced pressure, crush, obtain dry extract, as Radix Rehmanniae extract, Radix Scrophulariae extract.
2) filler is crushed to mean diameter with lubricant super micron mill<50 μm, the Radix Rehmanniae is carried
Take thing, Radix Scrophulariae extract and 80-120 mesh sieve is crossed, be subsequently filled agent, lubricant, Radix Rehmanniae extract, Radix Scrophulariae extract and mix in proportion
Mixture is after conjunction；
3) Radix Rehmanniae extract, Radix Scrophulariae extract, filler and lubricant are weighed mixture, adds to Wet mixed granulating machine
In, mixing speed 500r/min is set, 1000 r/min of speed is shredded, mix 8 min；
4) mixture is made preparation, by the loading amount filling 1 of 0.5 ± 10%g/ grain#Capsule shells；
5) finished product detection is carried out to capsule, is packed after finished product detection is qualified, during packaging, using medicinal high density polyethylene (HDPE)
Plastic bottle, is sealed with aluminum plastic film, interior plus silica-gel desiccant, is packed by 50/bottle or 100/bottle specifications.
Experiment detection
Impact pharmacology of the present invention also to the compatibility of Radix Rehmanniae extract and Radix Scrophulariae extract to diabetic mice fasting glucose is made
With being studied.
Experimental technique
Using ICR mice, body weight 18-22g, 80, after fasting (can't help water) 12h, tail vein injection alloxan, the next day carry out
Operation, alloxan dosage is 50mg/kg, to take blood in the 3rd day afterbody to alloxan, is surveyed with blood glucose meter empty after fasting 12h
Abdomen blood glucose value, using fasting glucose ＞ 12mmol/L as diabetic mice.Take successful 60 mices of modeling and be divided into 6 groups, respectively
For model control group, Radix Rehmanniae extract (400mg/kg), Radix Scrophulariae extract (400mg/kg), 1 (Radix Rehmanniae extract of compatibility
600+ Radix Scrophulariae extract 200) mg/kg, compatibility 2 (Radix Rehmanniae extract 400+ Radix Scrophulariae extract 400) mg/kg, compatibility 3 (freshly
Yellow extract 200+ Radix Scrophulariae extract 400) mg/kg oral dose group, per 10 are organized, separately set one group of intact animal's work blank right
According to matched group feeds water (10ml/kg).It is administered once daily, successive administration 20d, 10d survey a fasting glucose, fasting before test
Can't help water 12h.
Data statistics processing：To each result of the test measured value, measurement data is checked between Student ' t group, is counted
Data Ridit method carries out organizing a significance test, judges significant difference.
Experimental result：
Higher level being maintained in non-administered group blood glucose value 20d, detecting blood glucose after administration 10d, different composition of prescription 800mg/kg are equal
Blood glucose rise can be significantly inhibited, wherein optimal with Radix Rehmanniae extract 600, Radix Scrophulariae extract 200mg/kg compatibility.And single medicinal material
Radix Rehmanniae extract 800mg/kg, Radix Scrophulariae extract 800mg/kg do not show that significance is acted on, and the results are shown in Table.Show that Radix Rehmanniae is carried
Take after thing, Radix Scrophulariae extract carry out compatibility and drug effect can be significantly improved, played significant synergism.
Table 1 is the impact (X of Radix Rehmanniae extract, Radix Scrophulariae extract and its compatibility to blood glucose in diabetic mice (mmol/L)
±S)
| Group | Dosage mg/kg | Number of animals（Only） | Blood glucose value before administration | Rear 10 days blood glucose values are administered | Rear 20 days blood glucose values are administered |
| Control | 10 | 6.02±0.79 | 6.52±0.58 | 6.36±0.80 | |
| Model | 10 | 20.34±2.03 | 26.11±6.57 | 26.47±4.06 | |
| Radix Rehmanniae extract | 800 | 10 | 20.35±5.22 | 23.02±3.16 | 22.54±7.10 |
| Radix Scrophulariae extract | 800 | 10 | 21.63±3.87 | 24.11±4.35 | 23.58±5.68 |
| Compatibility 1 | 600+200 | 10 | 19.84±5.17 | 20.02±3.78* | 19.71 ± 4.16* |
| Compatibility 2 | 400+400 | 10 | 20.39±3.29 | 22.83±4.12* | 22.57±3.25* |
| Compatibility 3 | 200+600 | 10 | 21.23±7.58 | 23.79±7.56 | 22.15±4.39* |
Table 1
Note：Model group compares #P ＜ 0.05, ##P ＜ 0.01 with matched group
Administration group is compared with model group*P ＜ 0.05,**P ＜ 0.01；
Result above can be seen that single medicinal material Radix Rehmanniae extract, Radix Scrophulariae extract in compound recipe has one to blood glucose in diabetic mice
Fixed inhibitory action trend, but no significance,statistical effect.Show after two taste medicine compatible combination that the collaboration of more preferable drug effect is made
With its drug effect is significantly higher than the effect of commensurability single medicinal material in compound recipe.
The Chinese medicine for the treatment of diabetes is obtained i.e. with fast compared with treatment Chinese medicine for treating diabetes blood sugar lowering speed currently on the market；The present invention
The Chinese medicine hypoglycemic effect that treatment diabetes are obtained more preferably becomes apparent from, and the side effect of no Western medicine.
Claims (7)
1. a kind of Chinese medicine preparation for treating diabetes, it is characterised in that including the component of following weight portion：Radix Rehmanniae extract
25-75 part, Radix Scrophulariae extract 25-50 part, filler 330-380 part, lubricant 0-20 part.
2. according to claim 1 treatment diabetes Chinese medicine preparation, it is characterised in that described filler be starch,
Lactose, sucrose, Hypromellose, Icing Sugar, dextrin, pregelatinized Starch, sorbitol, Mannitol, calcium sulfate, in Calcium Carbonate one
Plant or several.
3. according to claim 1 treatment diabetes Chinese medicine preparation, it is characterised in that the lubricant be stearic acid
Magnesium, micropowder silica gel, one or more in Pulvis Talci.
4. according to claim 1 treatment diabetes Chinese medicine preparation, it is characterised in that the Chinese medicine of the treatment diabetes
Agent system preferably constitute for：Radix Rehmanniae extract 75g, Radix Scrophulariae extract 25g, adjuvant 355g, lubricant 10g.
5. according to claim 1 treatment diabetes Chinese medicine preparation, it is characterised in that described Chinese medicine preparation can be made into
Capsule.
6. the preparation method for treating the Chinese medicine preparation of diabetes as defined in claim 1 is made：Characterized in that, including
Following steps；
Take Radix Rehmanniae, appropriate Radix Scrophulariae respectively, the thin slice of 0.5cm or so is cut into, respectively plus 5～10 times amount decoctings boil 2～3 times, every time
Each 0.5～2 hour, collecting decoction, filtration, it is concentrated into thick paste of the relative density for 1.30～1.35 (60 DEG C), drying under reduced pressure, powder
Broken, obtain dry extract and be Radix Rehmanniae extract, Radix Scrophulariae extract.
7. the filler is crushed with super micron mill with lubricant, the Radix Rehmanniae extract, Radix Scrophulariae extract are crossed 80-
120 mesh sieves, are subsequently filled agent, lubricant, Radix Rehmanniae extract, Radix Scrophulariae extract and are mixture after being mixed in proportion；
Add in Wet mixed granulating machine by mixture, mixing speed 500r/min is set, shred 1000 r/min of speed, mixing
8 min；
Mixture is made preparation, finished product detection is carried out to preparation, packed after finished product detection is qualified.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611217269.0A CN106421105A (en) | 2016-12-26 | 2016-12-26 | Traditional Chinese medicine preparation for treating diabetes and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611217269.0A CN106421105A (en) | 2016-12-26 | 2016-12-26 | Traditional Chinese medicine preparation for treating diabetes and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106421105A true CN106421105A (en) | 2017-02-22 |
Family
ID=58215632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611217269.0A Pending CN106421105A (en) | 2016-12-26 | 2016-12-26 | Traditional Chinese medicine preparation for treating diabetes and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106421105A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199664A (en) * | 2006-12-13 | 2008-06-18 | 中国医药研究开发中心有限公司 | Chinese medicine for treating diabetic and prescription |
| CN101695363A (en) * | 2009-11-02 | 2010-04-21 | 阳瑞鸿 | Fermented soybean paste health care product |
-
2016
- 2016-12-26 CN CN201611217269.0A patent/CN106421105A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199664A (en) * | 2006-12-13 | 2008-06-18 | 中国医药研究开发中心有限公司 | Chinese medicine for treating diabetic and prescription |
| CN101695363A (en) * | 2009-11-02 | 2010-04-21 | 阳瑞鸿 | Fermented soybean paste health care product |
Non-Patent Citations (2)
| Title |
|---|
| 王强虎等: "《糖尿病绿色疗法》", 31 August 2014, 人民军医出版社 * |
| 王辉等: "《糖尿病患者医食住行》", 31 October 2013, 金盾出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103054044B (en) | Sleep-improving health food composition | |
| CN105105116A (en) | Health food with effects of relieving physical fatigue and enhancing immunity and preparation method of health food | |
| KR20160110369A (en) | Drug combination, method of preparing same, and use thereof | |
| CN104055871A (en) | Traditional Chinese medicinal composition for improving sleeping quality and application of traditional Chinese medicinal composition | |
| CN104274509A (en) | Health product composition containing cordyceps sinensis and male flower of eucommia ulmoides as well as preparation method and application of health product composition | |
| CN104489674B (en) | A kind of composition and its preparation for alleviating exercise induced fatigue | |
| CN101380346A (en) | Traditional Chinese composition for treating tumor and production method thereof | |
| CN1233389C (en) | Chinese materia medica preparation made from gen-seng and astragalus root for strengthening the body resistance and anti cancer as well as producing method | |
| CN1205974C (en) | Thirty-six ingredients capsule for treating diabetes | |
| CN107982286A (en) | A kind of cordyceps sinensis lozenge and preparation method thereof | |
| CN1857285A (en) | Capsule for treating cardiac and cerebral vascular diseases and its preparing method and application | |
| CN106421105A (en) | Traditional Chinese medicine preparation for treating diabetes and preparation method thereof | |
| CN1401365A (en) | Chinese health medicine | |
| CN101032524B (en) | Application of martianus dermestoides in producing oxygen-deficient resisting medicine or healthy food | |
| CN101491605A (en) | Combination with blood sugar reducing function and preparation method thereof | |
| CN100348221C (en) | Ginseng and aconite tablet for treating qi vacuity and yang desertion and its preparation method | |
| CN112494569A (en) | Traditional Chinese medicine composition for improving immunity and preparation method and application thereof | |
| CN107929512B (en) | Method for preparing bone strengthening Longmu granules by adopting ultrahigh pressure extraction | |
| CN1070827A (en) | Up-to-date therapeutic agent of diabetes and method for making thereof | |
| CN105125616A (en) | Traditional Chinese medicine composition having function of improving anoxia endurance | |
| CN101143180A (en) | Medicine for treating diabetes | |
| CN1331491C (en) | Ginseng and aconite transfusion for treating qi vacuity and yang desertion and its preparation method | |
| CN100471488C (en) | Chinese medicine composition for transquilizing, warming Yang, benefiting Qi and nourishing heart and its prepn | |
| CN113018404A (en) | Blood stasis constitution health-care solid beverage and preparation method thereof | |
| CN104223066A (en) | Traditional Chinese medicine composition for improving sleeping |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170222 |