CN106177693A - A kind of Chinese medicine for treating eczema and compound recipe solution thereof - Google Patents

A kind of Chinese medicine for treating eczema and compound recipe solution thereof Download PDF

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CN106177693A
CN106177693A CN201610852490.7A CN201610852490A CN106177693A CN 106177693 A CN106177693 A CN 106177693A CN 201610852490 A CN201610852490 A CN 201610852490A CN 106177693 A CN106177693 A CN 106177693A
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fructus
eczema
folium
compound recipe
chinese medicine
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赵雪梅
高晗
卢梦诚
张勇
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Taishan Medical University
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Abstract

The invention discloses a kind of Chinese medicine for treating eczema and compound recipe solution thereof.For treating the Chinese medicine of eczema, including Herba Commelinae, Folium Fructus Broussonetiae, Fructus Xanthii, the Radix Stemonae, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli, Folium Perillae and Fructus Cnidii.A kind of compound recipe solution for treating eczema, including described Chinese medicine, sorbester p17 and sodium benzoate.The present invention uses Folium Fructus Broussonetiae, Fructus Xanthii, the Radix Stemonae, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli, Folium Perillae and Fructus Cnidii compatibility to help principal drug assistance Herba Commelinae with effect of its clearing heat and expelling damp, killing parasites for relieving itching；Gather clearing away heat-damp and promoting diuresis altogether in full side, eliminating fire and detoxication, and solution, during use, is spread upon affected part by the merit of dispelling wind for relieving itching, easy to use.

Description

A kind of Chinese medicine for treating eczema and compound recipe solution thereof
Technical field
The present invention relates to a kind of Chinese medicine for treating eczema and compound recipe solution thereof, belong to technical field of Chinese medicines.
Background technology
Eczema be by multiple internal and external factor cause a kind of have substantially ooze out the scytitis reaction of tendency, its clinical table Now there is the features such as symmetry, exudative, pruritic, pleomorphism and recurrent.Also be a kind of allergic inflammation dermatoses with Erythra multiformity, pruritus recurrent exerbation symmetrical, violent, easily develops into chronic being characterized.Any age, any can be betided Position, any season, asexuality difference；Have and ooze out tendency, the chronic course of disease, easy recurrent exerbation.The morbidity of eczema in recent years is presented The trend of liter, its pathogenic factor is complicated, has intrinsic factor and extrinsic factor to interact.Extrinsic factor such as living environment, weather bar Part, infection, diet, medicine etc. all can affect the generation of eczema.Environmental stimuli such as daylight, ultraviolet, cold, sweltering heat, hyperhidrosis, scratch Grabbing, rub and various animal skin, plant, cosmetics, detergent, fiber etc. all can induce eczema, some food also can lure Send out eczema to increase the weight of.Intrinsic factor are mainly allergic diathesis, are arranged by inherited genetic factors.Other are such as chronic digestive system disease, gastrointestinal The spirit such as road functional disorder, psychentonia, insomnia, fatigue, emotion changes changes, infection focus, dysbolism With endocrine function imbalance etc., all can produce or add the state of an illness of celsus' papules.
Recently the Number of Outpatients showed increased of various big hospital outpatient service eczema patients, has easy recurrent exerbation, the most serious Feature, the Symptoms with women and child especially is the most prominent, brings a lot of misery to patient, have impact on quality of life.Separately Outward, owing to the cause of disease of eczema is more complicated, treating the most thorny, simple western medicine curative effect is the most satisfied, as Most patients is commonly used External-applied ointment, liquid medicine containing hormonal components are smeared, and side effect is big, once drug withdrawal, will recurrent exerbation, even cause the state of an illness to enter One step deteriorates.China's Chinese medicine defines unique effective method from etiology and pathogenesis to clinical treatment to this disease in recent years, its Therapeutic effect is notable, and relapse rate substantially reduces, and the advantage of Chinese medicine eczema increasingly comes into one's own；In terms for the treatment of, outward The record of method for the treatment of is the most detailed, and in particular according to eczema character, site of pathological change is different and selects the external treatment principle of appropriate dosage forms medicine Use till today.Therefore the Chinese medicine preparation developing external curing eczema evident in efficacy, that toxic and side effects is little, easy to use just becomes outstanding For urgently.
The treatment of eczema uses Chinese medicine, Western medicine or the method for Chinese medicine Western medicine drug combination.Owing to the cause of disease of eczema is more multiple Miscellaneous, to treat the most thorny, simple western medicine curative effect is the most satisfied, and the advantage of Chinese medicine eczema comes into one's own in recent years, because of wet The record of rash external treatment is detailed, and according to eczema character, site of pathological change is different and selects appropriate dosage forms, external therapy of Chinese herb principle edge always With so far.At present, the externally-applied soft ointment of western medicine eczema specifically includes that Dexamethasone ointment, cortisone ointment, prednisone are soft Cream, Piyanping ointment, Ketoconazol/Clobetasol Propionate ofloxacin ointment (original name Botai ointment), Heparin ointment (low molecular sodium heparin, glass Glass acid sodium, allantoin, azone etc. form), Eloson ointment, fluocinolone acetonide ointment, Compound Flumetasone Ointment, hydrocortisone butyrate Ointment etc., based on hormone medicine；But, if long-term or short time heavy dose use hormonal medicaments treatment, fertilizer can be caused Fat, hirsutism, acne, blood glucose rising, hypertension, sodium retention, edema, the reduction of blood potassium, menoxenia, osteoporosis, aseptic bone The complication such as matter necrosis, gastric and duodenal ulcers.Kidney also can be caused certain infringement, also can cause body sugar, protein, A series of substance metabolismes such as fat and Water-Electrolyte are disorderly, destroy defence system and the suppression immunoreation ability of body.If Some patients are over the course for the treatment of because using corticosteroids medicine, and the dependency creating hormone, protopathy after drug withdrawal Become knock-on and increase the weight of the side effect with secondary, patient can be made to produce the biggest misery.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of Chinese medicine for treating eczema and compound recipe is molten Liquid.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine for treating eczema, including Herba Commelinae, Folium Fructus Broussonetiae, Fructus Xanthii, the Radix Stemonae, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli, Folium Perillae and Serpentis Machine tool.
Described a kind of Chinese medicine for treating eczema, in terms of parts by weight, including Herba Commelinae 2000-3000 part, paper mulberry Fructus Persicae Leaf 20-40 part, Fructus Xanthii 10-40 part, Radix Stemonae 10-40 part, Radix Sophorae Flavescentis 20-40 part, Pericarpium Zanthoxyli 20-40 part, Folium Perillae 20-40 part and Serpentis Machine tool 20-40 part.
A kind of compound recipe solution for treating eczema, including described Chinese medicine, also includes sorbester p17 0.001-0.003 part With sodium benzoate 0.01-0.05 part.
The preparation method of described a kind of compound recipe solution for treating eczema, including following step:
(1) preparation of volatile oil: take Fructus Cnidii, Pericarpium Zanthoxyli and Folium Perillae and pulverize, after adding cold water soak, pass through vapor distillation Method, extracts 7 hours, collects fraction, obtains volatile oil, and volatile oil is standby；Solution filters, and obtains filtering residue a, and filtrate a is standby；
(2) preparation of the fresh juice of Herba Commelinae: fresh Herba Commelinae is cleaned, drained, squeeze juice in squeezer, obtains Herba Commelinae fresh Juice；
(3) preparation of compound recipe solution: taking Radix Sophorae Flavescentis, the Radix Stemonae, Fructus Xanthii and Folium Fructus Broussonetiae and pulverize, merge above-mentioned filtering residue a, add water merceration 1h, heating decocts 2 times, filters filtrate b and merges concentration with above-mentioned filtrate a；Add ethanol, 10 DEG C arranged below overnight, filter, wave Alcohol is to obtaining medicinal liquid, the volatile oil obtained in combining step (1) without alcohol taste, and adds sorbester p17 and sodium benzoate, adds Herba Commelinae Fresh juice, to 1000ml, mixing, filters to obtain compound recipe solution.
In described step (1), the weight adding cold water is Fructus Cnidii, Pericarpium Zanthoxyli and 14 times of Folium Perillae gross weight.
In described step (3), described addition ethanol to alcohol content is 80%.
Tradescantia albiflora (Commelina communisL.) it is the herb of Herba Commelinae kind plant Herba Commelinae, receives for Chinese Pharmacopoeia One of medical material kind carried, it has heat-clearing and toxic substances removing, inducing diuresis and reducing edema, antipruritic effect.Another name chicken SHECAO, nose hack bamboo careless, green (supplement to the Herbal), Bi Zhucao (" Bencao Tujing "), blue or green earrings flower, green Bufo siccus, bamboo grass (" record in detail of bamboo spectrum "), earrings grass (" generation Cure to obtain efficacious prescriptions ") etc..Chemical composition is containing anthocyanidin glucoside compound delphinidin, the double glucoside-Radix Consolidae of delphinidin Glycosides, awobanin glycosides etc., additionally, also containing duck sole of the foot flavone and polypeptide glycosides etc..Studies have reported that [Lv Yisheng, Li Suqin, Ding Ruimei. duck Toe medical herbs pharmacological research. the college journal of Anhui medical courses in general, 1995,30(3): 244-245.] the Preliminary pharmacological effect of Tradescantia albiflora, Experiment proves that Tradescantia albiflora liquid has obvious easing pain and diminishing inflammation effect.Golden yellow Pu grape coccus, Candida albicans all there is antibacterial work With, ill vitro antibacterial endotoxin effect increases along with the prolongation of incubation time, this result of study and the contained heat reliving and toxin-eliminating of pharmacopeia Act on more consistent.Ten thousand capitals etc. [ten thousand capitals, Zhang Xiaolian, Xin Shanlu. the bacteriostasis research of Tradescantia albiflora. public health is with pre- Anti-medical science, 2005,16(1): 25-27.] by the bacteriostasis of agar diffusion method detection Herba Commelinae, and it is real to have carried out acute toxicity Test, found that Herba Commelinae all has stronger inhibitory action to dysentery bacterium, bacillus subtilis, escherichia coli etc., acute Toxicity test display Commelina is in the nontoxic or material of low toxicity.The traditional Chinese medical science is frequently with interior disease external therapy, special effect.Zhao Yanyun etc. [Zhao Yanyun, Mo Ailian, room is big preferably etc. Tradescantia albiflora external treatment hordeolum 103 example. and People's Armed Police's medical college journal, 1997,6(4): 254.] Pressing painting treatment hordeolum with being coated with, bake juice outside fresh Herba Commelinae liquid, clinical observation has definite curative effect.Cui Suxing [Cui Suxing. Tradescantia albiflora Control miliaria furuncle and have special effect. the Sichuan traditional Chinese medical science, 1999,17(1): 42.] take the treatment of medicinal liquid washout, prevention miliaria with fresh Herba Commelinae Sub-furuncle, effect is the best.
Folium Fructus Broussonetiae i.e. Folium Broussonetiae (" not Lu "), for the leaf of moraceae plants Broussonetia papyrifera.Another name: structure leaf (" the secret record of primary and secondary "), Broussonetia papyrifera leaf (" easy folk prescription "), beans Huang leaf (" the SHENGCAO property of medicine is standby to be wanted ").Chemical composition contains flavonoid glycoside, phenols, organic acid, tannin.Sweet in the mouth, property Cool, nontoxic.Function cures mainly: removing heat from blood, diuretic.Folium Fructus Broussonetiae is a kind of Chinese crude drug, and it is generally used for treating psoriasis etc., has certain Curative effect.Treatment pruritus and chronic urticaria are the most effective in cure.Li Shizhen (1518-1593 A.D.) concludes the therapeutic effect of leaf of Broussonetia papyrifera(L.) Vent., has following several: profit is little Just, curing rheumatism, controlling swelling, control nebulousurine, go hernia, control tinea skin ulcer, the effect wherein controlling tinea skin ulcer is fine.Among the people for controlling tinea pruritus due to damp pathogen not Can bear: Folium Broussonetiae half jin, fritter to smash and make completely mashed, spread on (Holy Benevolent Prescriptions) in tinea.It is antibacterial that modern pharmacology research shows that Folium Broussonetiae has Effect: the acetone extract of Folium Broussonetiae has inhibitory action to staphylococcus.
Fructus CnidiiCnidium monnieri(L.) Cuss., for the dry mature fruit of samphire cnidium monnieri.Another name: Serpentis rice, Serpentis pearl, Serpentis foxtail millet, cnidium monnieri core, cnidium monnieri reality, gas fruit, Radix Habenariae Dentatae, favus-infected head beggar, wild Fructus Foeniculi.Acrid in the mouth；Bitter；Warm in nature.Chemistry becomes Point: fruit contains volatile oil 1.3%, is mainly composed of pinene, camphene, bornival, isoborneol.Again containing osthole, Cnidimine, isopimpinellin, bergapton, columbianetin and angelate, acetas and isovalerate, cnidium monnieri Fixed, isobutyryl epoxide o-acetylcolumbianetin.Effect and effect: warming the kidney to invigorate YANG；Removing dampness and killing parasites；Dispelling wind for relieving itching.Cure mainly man Sexual impotence；Scrotum pruritus due to damp pathogen；Woman's infertility；Cold-damp leukorrhagia；Pudendal pruritus swells and ache；Rheumatic arthralgia；Eczema scabies.For sexual impotence, cold womb, Cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago；External treatment vulval eczema, married woman's pudendal pruritus；Trichomonal vaginitis.Clinical treatment acute exudative dermatosis And skin eczema, such as chronic eczema acute attack, pompholyx erosion phase, eczema scrotum, pruritus vulvae, scabies, tinea etc..
Radix Sophorae Flavescentis (Sophorae FlavescentisRadix.), another name: matrine (" detailed outline "), chuanshentong (" Guizhou side among the people Medicine collection "), phoenix claw (" Guangxi Chinese veterinarian's medicine is planted "), cattle ginseng (" Hunan medicine will ").Medicinal part is bean kind plant Radix Sophorae Flavescentis Root.Root contains multiple alkaloid: d-Matrine, d-Oxymatrine, sophoranl l-Anagyrine, l-methylcytisine, l-wear leaf Counterfeit indigo alkali and sophocarpine.Also containing flavonoid: xanthohumol, isoxanthohumol, 3,4 ', 5-tri-hydroxyl-7-methoxy-8-isoamylene radical chromocor, 8-prenylkaempferol etc..Function cures mainly: heat clearing away, dampness, parasite killing.Control toxic-heat and blood stasis, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, Infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, mange malignant boil, erosion of vulva pruritus due to damp pathogen, scrofula, scald.Outward Control trichomonal vaginitis." book on Chinese herbal medicine justice " speech: " Radix Sophorae Flavescentis, big bitter Great Cold, drop-down of bringing down a fever, cleanse wet fire, its effect and a kind of reed mentioned in ancient books, company, dragon Gallbladder is the most close, and the hardship of Radix Sophorae Flavescentis is more, and it is dry the strongest, therefore can kill the damp and hot worm given birth to, strong compared with Radix Scutellariae, Rhizoma Coptidis strength benefit.Person of modern times Be dare not to enter decoct, cover its bitterness difficulty of the most special fear clothes, also dislike it high strict and keep away also.So poison wind dislikes leprosy, and non-this does not removes." " Yunnan South book on Chinese herbal medicine " record: " removing heat from blood, relieving heat toxin, mange, impetigo poison.Treat skin pruritus, blood tinea corporis scabies, naughty white scales." historically It can be seen that Radix Sophorae Flavescentis bitter cold, function heat clearing and damp drying, killing parasites for relieving itching, diuresis of relieving oedema or abdominal distension through diuresis or purgation, to being born in the eczema of skin, eczema, carbuncle Infections, swollen, poison have special efficacy.
Fructus Xanthii, for the fruit of the drying and ripening band involucre of feverfew Herba Xanthii.Another name: ear is real (" herbal classic "), ox louse Son (" Guizhou side among the people medicine collection "), son (" medical material compilation of data ") of recklessly getting into bed, grey youth's kind, cotton Mantidis (" medicine will is planted in Jiangsu "), grey son, Hu Cangzi (" will planted by northeast medicine "), starves louse (" Guangxi Chinese medicinal herbal "), grey stalk, Herba Xanthii Fructus Tribuli (" Shaanxi Chinese herbal medicine ").Distribution In Heilungkiang, Liaoning, Jilin, the Inner Mongol, Hebei, the ground such as Anyang.Bitter in the mouth, sweet, pungent, warm in nature.It is mainly composed of containing xanthostrumarin, Herba Xanthii oil (wherein having a large amount of linoleic acid), Herba Xanthii toxalbumin, vitamin C etc..Effect and effect: dispersing wind and cold；Clearing the nasal passage；Dispel Rheumatism；Antipruritic.Main nasal sinusitis；Headche due to wind-cold；Rheumatic arthralgia；Rubella；Eczema；Scabies.For headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella Pruritus, arthralgia chiefly caused by damp pathogen contracture.Clinical pharmacology research confirms, Fructus Xanthii, rich in volatile oil, can be improved BITONG gas and olfactory function, and have anti- Bacterium, antiinflammatory, improves nasal mucosa blood circulation, alleviates the effects such as vascular permeability.
The Radix Stemonae (Classification system: Stemona japonica) is also known as mother-in-law woman grass, and medicine louse medicine, is the plant of Stemonaceae.Sweet, Hardship, tepor.The Radix Stemonae rich in there being substantial amounts of alkaloid, root containing (-)-Stemoninine, tuberostemonine, this for peaceful alkali, secondary (-)-Stemoninine, oxidation hundred Portion's alkali.The most sugary 2.32%, lipid 0.84%, protein 9.25%, ash 12.1%, and acetic acid, formic acid, malic acid, succinic acid, Oxalic acid etc..Outer for head louse, body louse, enterobiasis, pudendum Pruritus.Guangzhou army " conventional Chinese herbal medicine handbook " points out that the Radix Stemonae can control hundred Day is coughed, pulmonary tuberculosis, bronchitis, dermatitis, eczema, urticaria, tinea pedis, amebic dysentery.
Pericarpium Zanthoxyli (formal name used at school:Zanthoxylum bungeanumMaxim.), another name: big green pepper (" elegant "), Pericarpium Zanthoxyli, another name for Sichuan Province green pepper (" herbal classic "), south green pepper (Lei Gong's Treatise on Preparation and Broiling of Materia Medica), bar green pepper, (" not Lu "), antiperspirant green pepper (TAO Hong-Jing), (" property of medicine opinion "), the Chinese be dialled in land Green pepper (" Japan hanako materia medica "), Fructus Zanthoxyli (Holy Benevolent Prescriptions), some green pepper (" detailed outline ").Medicinal part is the peel of rutaceae Pericarpium Zanthoxyli. Pericarpium Zanthoxyli fruit containing volatile oil 0.7%(Guizhou produce), 2～4%(Gansu produce), 4～9%(Guangdong produce).In volatile oil containing geraniol, Limonene, cumic alcohol etc..Fruit is still containing sterol, unsaturated organic acid etc..Function cures mainly: warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, and parasite killing solves Fish raw meat poison.Control food stagnation and stop drink, trusted subordinate's cold type of pain, vomit, oh, cough with dyspnea, anemofrigid-damp arthralgia, have loose bowels, dysentery, colic, toothache, ascarid Parasitosis, enterobiasis, pudendal pruritus, skin ulcer scabies.
Folium Perillae, another name: Soviet Union, Folium Perillae, Thallus Porphyrae.Medicinal part is the leaf of labiate wrinkle Folium Perillae, point Folium Perillae etc..Property Taste: pungent, tepor, nontoxic.Chemical composition: wrinkle Folium Perillae herb, containing volatile oil about 0.5%, includes perillaldehyde about 55%, left-handed limonene 20～30% and australene a small amount of.Also containing arginine, cumfrey, cyanidin 3-(6-is to coumaric acyl-β-D-Glucose glycosides) 5-β-D- Glucoside.Containing isoegomaketone etc. in the volatile oil of leaf.Point Folium Perillae herb containing volatile oil, include isopentyl-3-furyl ketone, Perillaldehyde, α-and nopinene, (R)-4-isopropenyl-1-methyl-1-cyclohexene, l-linalool, camphene, menthol, menthone, perilla alcohol, dihydroperilla alcohol, fourth Oleum sesami phenol.Modern pharmacology research shows that Folium Perillae in vitro can suppress aureus growth.Folium Perillae extractum is to 6 kinds of funguses Agar culture minimum inhibitory concentration (MIC) is 200-1600mg/ml；Perillaldehyde in extractum plays main bacteriostasis.Clinical Application can treat verruca vulgaris.
The beneficial effect that the present invention is reached:
The present invention uses Folium Fructus Broussonetiae, Fructus Xanthii, the Radix Stemonae, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli, Folium Perillae and Fructus Cnidii compatibility with its clearing heat and expelling damp, kills Effect assistant principal drug assistance Herba Commelinae that worm is antipruritic；Gather clearing away heat-damp and promoting diuresis altogether in full side, and eliminating fire and detoxication, the merit of dispelling wind for relieving itching, during use, by molten Liquid spreads upon affected part, easy to use.
Development cost of the present invention is relatively low, therapeutic effect good, not impairing the liver kidney, short treating period, without any side effects, do not produce medicine Thing dependency, easy to use, not only provide new kind by the clinical application for eczema, also bring considerable warp for manufacturing enterprise Ji benefit.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine for treating eczema, in terms of parts by weight, including Herba Commelinae 2000 parts, Folium Fructus Broussonetiae 20 parts, Fructus Xanthii 40 Part, the Radix Stemonae 10 parts, Radix Sophorae Flavescentis 40 parts, 40 parts of Pericarpium Zanthoxyli, Folium Perillae 40 parts and Fructus Cnidii 40 parts.
A kind of compound recipe solution for treating eczema, including described Chinese medicine, also includes sorbester p17 0.001 part and benzoic acid 0.01 part of sodium.
The preparation method of described a kind of compound recipe solution for treating eczema, including following step:
(1) preparation of volatile oil: take recipe quantity Fructus Cnidii, Pericarpium Zanthoxyli, Folium Perillae is suitably pulverized, cold water soak 0.5h, adds 14 times of water, By steam distillation, extracting 7 hours, collect fraction, volatile oil is standby；Solution filters, and obtains filtering residue a, and filtrate a is standby；
(2) preparation of the fresh juice of Herba Commelinae: fresh Herba Commelinae aerial parts is cleaned, drained, with squeeze juice in squeezer；
(3) preparation of compound recipe solution: taking recipe quantity Radix Sophorae Flavescentis, the Radix Stemonae, Fructus Xanthii, Folium Fructus Broussonetiae is suitably pulverized, and merges above-mentioned filtering residue a, Adding 16 times of water-cooleds leaching 1h, heating decocts 2 times, each 2h, filters filtrate b and merges with above-mentioned filtrate a and be concentrated into 1:1.Add ethanol Be 80% to alcohol content, 10 DEG C arranged below overnight, filter, wave alcohol to without alcohol taste gained medicinal liquid merging above-mentioned collection volatile oil, And add sorbester p17 and sodium benzoate, and add the fresh juice of Herba Commelinae to 1000ml, mixing, filter to obtain the aqueous solution of preparation.
Embodiment 2
A kind of Chinese medicine for treating eczema, in terms of parts by weight, including Herba Commelinae 3000 parts, Folium Fructus Broussonetiae 40 parts, Fructus Xanthii 10 Part, the Radix Stemonae 40 parts, Radix Sophorae Flavescentis 20 parts, 20 parts of Pericarpium Zanthoxyli, Folium Perillae 20 parts and Fructus Cnidii 20 parts.
A kind of compound recipe solution for treating eczema, including described Chinese medicine, also includes sorbester p17 0.003 part and benzoic acid 0.05 part of sodium.
The preparation method of described a kind of compound recipe solution for treating eczema, including following step:
(1) preparation of volatile oil: take recipe quantity Fructus Cnidii, Pericarpium Zanthoxyli, Folium Perillae is suitably pulverized, cold water soak 0.5h, adds 14 times of water, By steam distillation, extracting 7 hours, collect fraction, volatile oil is standby；Solution filters, and obtains filtering residue a, and filtrate a is standby；
(2) preparation of the fresh juice of Herba Commelinae: fresh Herba Commelinae aerial parts is cleaned, drained, with squeeze juice in squeezer；
(3) preparation of compound recipe solution: taking recipe quantity Radix Sophorae Flavescentis, the Radix Stemonae, Fructus Xanthii, Folium Fructus Broussonetiae is suitably pulverized, and merges above-mentioned filtering residue a, Adding 16 times of water-cooleds leaching 1h, heating decocts 2 times, each 2h, filters filtrate b and merges with above-mentioned filtrate a and be concentrated into 1:1.Add ethanol Be 80% to alcohol content, 10 DEG C arranged below overnight, filter, wave alcohol to without alcohol taste gained medicinal liquid merging above-mentioned collection volatile oil, And add sorbester p17 and sodium benzoate, and add the fresh juice of Herba Commelinae to 1000ml, mixing, filter to obtain the aqueous solution of preparation.
Embodiment 3
A kind of Chinese medicine for treating eczema, in terms of parts by weight, including Herba Commelinae 2500 parts, Folium Fructus Broussonetiae 30 parts, Fructus Xanthii 20 Part, the Radix Stemonae 30 parts, Radix Sophorae Flavescentis 30 parts, 30 parts of Pericarpium Zanthoxyli, Folium Perillae 30 parts and Fructus Cnidii 30 parts.
A kind of compound recipe solution for treating eczema, including described Chinese medicine, also includes sorbester p17 0.002 part and benzoic acid 0.03 part of sodium.
The preparation method of described a kind of compound recipe solution for treating eczema, including following step:
(1) preparation of volatile oil: take recipe quantity Fructus Cnidii, Pericarpium Zanthoxyli, Folium Perillae is suitably pulverized, cold water soak 0.5h, adds 14 times of water, By steam distillation, extracting 7 hours, collect fraction, volatile oil is standby；Solution filters, and obtains filtering residue a, and filtrate a is standby；
(2) preparation of the fresh juice of Herba Commelinae: fresh Herba Commelinae aerial parts is cleaned, drained, with squeeze juice in squeezer；
(3) preparation of compound recipe solution: taking recipe quantity Radix Sophorae Flavescentis, the Radix Stemonae, Fructus Xanthii, Folium Fructus Broussonetiae is suitably pulverized, and merges above-mentioned filtering residue a, Adding 16 times of water-cooleds leaching 1h, heating decocts 2 times, each 2h, filters filtrate b and merges with above-mentioned filtrate a and be concentrated into 1:1.Add ethanol Be 80% to alcohol content, 10 DEG C arranged below overnight, filter, wave alcohol to without alcohol taste gained medicinal liquid merging above-mentioned collection volatile oil, And add sorbester p17 and sodium benzoate, and add the fresh juice of Herba Commelinae to 1000ml, mixing, filter to obtain the aqueous solution of preparation.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For Yuan, on the premise of without departing from the technology of the present invention principle, it is also possible to make some improvement and deformation, these improve and deformation Also should be regarded as protection scope of the present invention.

Claims (6)

1., for treating a Chinese medicine for eczema, it is characterized in that, including Herba Commelinae, Folium Fructus Broussonetiae, Fructus Xanthii, the Radix Stemonae, Radix Sophorae Flavescentis, flower Green pepper, Folium Perillae and Fructus Cnidii.
A kind of Chinese medicine for treating eczema the most according to claim 1, is characterized in that, in terms of parts by weight, including duck Sole of the foot grass 2000-3000 part, Folium Fructus Broussonetiae 20-40 part, Fructus Xanthii 10-40 part, Radix Stemonae 10-40 part, Radix Sophorae Flavescentis 20-40 part, Pericarpium Zanthoxyli 20-40 Part, Folium Perillae 20-40 part and Fructus Cnidii 20-40 part.
3., for treating a compound recipe solution for eczema, including the Chinese medicine described in claim 2, it is characterized in that, also include span 80 0.001-0.003 parts and sodium benzoate 0.01-0.05 part.
The preparation method of a kind of compound recipe solution for treating eczema the most according to claim 3, is characterized in that, including with Under several steps:
(1) preparation of volatile oil: take Fructus Cnidii, Pericarpium Zanthoxyli and Folium Perillae and pulverize, after adding cold water soak, pass through vapor distillation Method, extracts 7 hours, collects fraction, obtains volatile oil, and volatile oil is standby；Solution filters, and obtains filtering residue a, and filtrate a is standby；
(2) preparation of the fresh juice of Herba Commelinae: fresh Herba Commelinae is cleaned, drained, squeeze juice in squeezer, obtains Herba Commelinae fresh Juice；
(3) preparation of compound recipe solution: taking Radix Sophorae Flavescentis, the Radix Stemonae, Fructus Xanthii and Folium Fructus Broussonetiae and pulverize, merge above-mentioned filtering residue a, add water merceration 1h, heating decocts 2 times, filters filtrate b and merges concentration with above-mentioned filtrate a；Add ethanol, 10 DEG C arranged below overnight, filter, wave Alcohol is to obtaining medicinal liquid, the volatile oil obtained in combining step (1) without alcohol taste, and adds sorbester p17 and sodium benzoate, adds Herba Commelinae Fresh juice, to 1000ml, mixing, filters to obtain compound recipe solution.
The preparation method of a kind of compound recipe solution for treating eczema the most according to claim 4, is characterized in that, described step Suddenly, in (1), the weight adding cold water is Fructus Cnidii, Pericarpium Zanthoxyli and 14 times of Folium Perillae gross weight.
The preparation method of a kind of compound recipe solution for treating eczema the most according to claim 4, is characterized in that, described step Suddenly, in (3), described addition ethanol to alcohol content is 80%.
CN201610852490.7A 2016-09-27 2016-09-27 A kind of Chinese medicine for treating eczema and compound recipe solution thereof Pending CN106177693A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1456170A (en) * 2003-05-19 2003-11-19 纪辉 External applied medicine composition containing vitamin B
CN1939319A (en) * 2005-09-28 2007-04-04 江苏正大天晴药业股份有限公司 Isoglycyrrhiza acid magnesium externally-applied preparation, its making method and usage
CN103566255A (en) * 2013-10-25 2014-02-12 汤旭静 Paper mulberry leaf lotion and preparation method thereof
CN104398643A (en) * 2014-11-14 2015-03-11 晏子辉 Traditional Chinese medicine composition treating dermatitis and eczema
CN104474098A (en) * 2014-12-10 2015-04-01 黄平县兴且民族民间中草医药科学发展有限责任公司 Traditional Chinese medicine preparation for treating intractable eczema
CN105727105A (en) * 2016-03-13 2016-07-06 华梅 External-use medicinal liquor for treating eczema and preparation method of external-use medicinal liquor
CN105853680A (en) * 2016-04-24 2016-08-17 李国玉 Cream for treating chronic eczema and preparation method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1456170A (en) * 2003-05-19 2003-11-19 纪辉 External applied medicine composition containing vitamin B
CN1939319A (en) * 2005-09-28 2007-04-04 江苏正大天晴药业股份有限公司 Isoglycyrrhiza acid magnesium externally-applied preparation, its making method and usage
CN103566255A (en) * 2013-10-25 2014-02-12 汤旭静 Paper mulberry leaf lotion and preparation method thereof
CN104398643A (en) * 2014-11-14 2015-03-11 晏子辉 Traditional Chinese medicine composition treating dermatitis and eczema
CN104474098A (en) * 2014-12-10 2015-04-01 黄平县兴且民族民间中草医药科学发展有限责任公司 Traditional Chinese medicine preparation for treating intractable eczema
CN105727105A (en) * 2016-03-13 2016-07-06 华梅 External-use medicinal liquor for treating eczema and preparation method of external-use medicinal liquor
CN105853680A (en) * 2016-04-24 2016-08-17 李国玉 Cream for treating chronic eczema and preparation method thereof

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