CN113546139A - Preparation for promoting smooth nasal circulation and preparation method thereof - Google Patents

Abstract

The invention belongs to the technical field of Chinese herbal medicines, and discloses a preparation beneficial to smooth nose and a preparation method thereof. Green tea is used for clearing heat, improving eyesight, sterilizing and diminishing inflammation; the ageratum has the effects of relieving exterior syndrome, relieving summer heat and sterilizing; the houttuynia cordata has the effects of inhibiting bacteria and removing heat, and the immunity is improved; lily bulb nourishing yin and moistening lung; semen Ginkgo has effects of astringing lung and relieving asthma; the liquorice clears away heat and toxic materials and harmonizes the drug property; yuzhu can nourish yin and moisten dryness; the seville orange flower can regulate qi and relieve chest stuffiness; purslane has the functions of bacteriostasis and inflammation diminishing; exocarpium Citri rubrum for regulating qi-flowing and relieving epigastric distention; the cogongrass rhizome is antibacterial; herba Lophatheri for inhibiting bacteria; flos Sophorae Immaturus is effective in clearing liver-fire and is rich in vitamins. The raw materials are all Chinese herbal medicines which are neutral in nature and sweet in taste and mainly enter lung and spleen channels, and the components are mild and harmonized, so that the nasal suppository can relieve nasal obstruction, clear away heat and toxic materials, resist bacteria and diminish inflammation, and has a good auxiliary effect on various nasal inflammations. The two preparation modes are selected to obtain two preparation finished products, and the two preparation finished products not only have simple preparation methods, but also are convenient to use, transport, long in storage time, free of toxic and side effects and free of irritation.

Description

Preparation for promoting smooth nasal circulation and preparation method thereof

Technical Field

The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a preparation beneficial to smoothness of a nose and a preparation method thereof.

Background

The nasal obstruction caused by cold usually results in rhinitis or sinusitis due to untimely treatment.

Rhinitis is a common disease, mainly manifested as nasal obstruction, watery nasal discharge, sneeze, hyposmia and other nasal symptoms, and chronic sinusitis is mostly manifested as heavy sensation in the head and is easy to be treated. It has high incidence and long course of disease, and if improper treatment or delayed treatment, it seriously damages the throat, trachea, lung and heart of human body and causes nasopharyngeal carcinoma, etc. Rhinitis is listed as one of the medical problems, and once the rhinitis is ill, the rhinitis brings pain to patients and brings great mental stress to families.

At present, the clinical treatment of acute and chronic rhinitis mostly adopts methods such as oral antibiotics, external laser, puncture flushing and the like. The methods have certain anti-inflammatory effect on rhinitis inflammation, but the treatment is temporary and permanent, the immunity of the organism can not be adjusted, so that the patients can not be helped to gradually get rid of the trouble of the rhinitis, and most of oral medicines have certain influence on the body.

Disclosure of Invention

In order to solve the problems in the prior art, the invention aims to provide a preparation for promoting nasal obstruction and a preparation method thereof.

The technical scheme adopted by the invention is as follows: the preparation for promoting nasal obstruction is characterized by being prepared from the following raw materials in parts by mass:

30-50 parts of green tea, 15-30 parts of ageratum, 15-25 parts of houttuynia cordata, 6-12 parts of lily, 3-9 parts of ginkgo, 20-46 parts of liquorice, 6-12 parts of polygonatum odoratum, 13-25 parts of seville orange flower, 9-15 parts of purslane, 3-10 parts of exocarpium citri rubrum, 10-30 parts of lalang grass rhizome, 16-29 parts of lophatherum gracile and 15-30 parts of sophora flower.

Green tea is produced with tea tree leaf or bud, and through deactivating enzyme, shaping, stoving and other technological processes, and has natural tea leaf components, tea polyphenol, catechin, chlorophyll, caffeine, amino acids, vitamins and other nutritious components maintained. The fixation plays a decisive role in the quality of the green tea. The characteristic of enzyme in the fresh leaves is destroyed through high temperature, and the oxidation of polyphenol substances is prevented, so that the red change of the leaves is prevented; at the same time, part of water in the leaves is evaporated to soften the leaves, thereby creating conditions for rolling and shaping. With the evaporation of water, the low boiling point aromatic substances with grass smell in the fresh leaves volatilize and disappear, so that the tea aroma is improved. Except for special tea, the process is carried out in a fixation machine. Factors influencing the fixation quality include fixation temperature, leaf feeding amount, fixation machine type, time, fixation mode and the like. They are a whole and are mutually connected and restricted. Due to its characteristics, it retains more natural substances in fresh leaves. Wherein, the tea polyphenol and the caffeine keep more than 85 percent of fresh leaves, the chlorophyll keeps about 50 percent, and the vitamin loss is less, thereby forming the characteristics of green tea, namely green leaves with clear soup and strong taste astringency. Has special effects on aging prevention, cancer resistance, sterilization, inflammation elimination and the like, and is not good enough for fermented tea and the like. Green tea is known as "national drink". Modern science has proved that the tea contains biochemical components closely related to human health, and the tea not only has the pharmacological actions of refreshing and clearing heart, clearing summer-heat, promoting digestion and reducing phlegm, removing greasiness and losing weight, clearing heart and relieving restlessness, detoxifying and sobering up, promoting the production of body fluid and quenching thirst, reducing pathogenic fire and improving eyesight, and stopping dysentery and removing dampness, but also has certain pharmacological efficacy on modern diseases, such as radiation disease, cardiovascular and cerebrovascular diseases, cancer and the like. The main components of the tea with pharmacological action are tea polyphenol, caffeine, lipopolysaccharide, theanine and the like.

Ageratum, academic name: agastache rugosa (fisch.et Mey.) o.ktze.; also named: hexiang, cang Ji and shan Feng Zi belong to Labiatae family perennial herb of Labiatae family. Aromatic oil can be extracted from stem and leaf of herba Agastaches. The ground part can be used as a medicine, has mild nature, pungent and sweet taste, has the functions of relieving summer-heat, resolving dampness, harmonizing stomach, stopping vomiting and the like, and is mainly used for treating diseases such as summer-heat and dampness, headache and fever, chest distress and abdominal distension, vomiting, diarrhea and the like. Agastache rugosa is also rich in nutrients and trace elements. Its tender stem, leaf and seedling contain calcium, carotene, protein, cellulose and various minerals, so that it can be used as vegetable, not only is palatable, but also is a health-care product. Herba Agastaches in cold sauce is often eaten in summer, and can be used for preventing common cold and summer dampness, and caring skin. The stem and leaf of Agastache rugosa can be used as aromatic oil for food industry and cosmetic industry. The nature and flavor are pungent and warm with meridian tropism. It enters spleen, stomach and lung meridians. It has the actions and indications of resolving turbidity with aromatics, regulating the middle warmer and arresting vomiting, relieving exterior syndrome and relieving summer-heat. Can be used for treating damp obstruction in middle warmer, abdominal distention, emesis, summer-heat dampness exterior syndrome, early stage of damp-warm syndrome, fever, listlessness, chest distress, cold-dampness, summer-heat, abdominal pain, emesis, diarrhea, nasosinusitis, and headache. Herba Agastaches has antibacterial effect, and can be used for removing halitosis, preventing infectious diseases, and as antiseptic. It is administered orally in summer by decocting herba Agastaches in porridge or making tea, and can be used for treating severe summer-damp disease, dampness obstruction of spleen and stomach, abdominal distention, physical weakness, nausea and emesis.

Cordate houttuynia, name of Chinese traditional medicine. Is dried aerial part of Houttuynia cordata Thunb of Houttuynia of Saururaceae. Has effects of clearing away heat and toxic materials, eliminating carbuncle, expelling pus, promoting urination, and treating stranguria. It can be used for treating lung abscess with purulent vomiting, cough due to lung heat, sore due to heat-toxin, carbuncle, stranguria due to damp-heat, and dysentery due to damp-heat. Pungent taste and slightly cold nature; it enters lung meridian. Chemical components: the product contains houttuynin, volatile oil, houttuynine, quercetin, potassium chloride, etc. The pharmacological action is as follows: the houttuynin has different degrees of inhibition effects on various gram positive and negative bacteria such as staphylococcus aureus, diplococcus pneumoniae, streptococcus A, bacillus influenzae, catacoccus, typhoid bacillus, tubercle bacillus and the like; it is non-volatile extracted with diethyl ether, and has antiviral effect. The product has effects in improving phagocytic ability of leukocyte, enhancing immunity, and relieving inflammation. The contained quercetin and potassium salt can dilate renal artery and increase renal artery blood flow, thus having stronger diuretic effect. In addition, it also has analgesic, hemostatic, tissue regeneration promoting, wound healing promoting, and antitussive effects.

Lily bulb, name of traditional Chinese medicine. Is a fleshy scaly leaf of Lilium Brownnii F.E.Brown var.viridulium baker or Lilium tenuifolium L.pulimum DC. Has the effects of nourishing yin, moistening lung, clearing away heart-fire and tranquilizing mind. It is mainly used for treating yin deficiency dry cough, cough with hemoptysis, insomnia and palpitation due to yin deficiency with heat, and heart-lung yin deficiency internal heat syndrome due to lily disease. Sweet in taste and slightly cold in nature; it enters lung, heart and stomach meridians. Chemical components: the product contains phenolic glyceride, propionate derivative, phenolic glycoside, phenolic glyceride glycoside, steroid alkaloid, trace elements, starch, protein, fat, etc. The pharmacological action is as follows: the lily water extract has the functions of relieving cough and eliminating phlegm for experimental animals; can be used for treating toad asthma caused by antihistamine; the lily water extract also has the effects of strengthening, tranquilizing and resisting allergy; the lily water decoction and alcohol precipitation solution has the function of hypoxia resistance; can also be used for preventing leukopenia caused by cyclophosphamide.

Gingko, name of traditional Chinese medicine. Is seed of Ginkgo biloba L. of Ginko of Ginkgoaceae. Has effects of astringing lung, relieving asthma, stopping leukorrhagia, and reducing urination. It can be used for treating asthma, cough with phlegm, leukorrhagia, whitish and turbid urine, frequent micturition, enuresis, etc. Sweet, bitter and astringent taste, mild in nature; it enters lung and kidney meridians.

Licorice, name of Chinese medicine. Is dried root and rhizome of Glycyrrhiza uralensis Fisch, Glycyrrhiza inflata Bat, or Glycyrrhiza glabra L of Glycyrrhiza of Leguminosae. Has the effects of tonifying qi and strengthening the middle warmer, moistening lung for arresting cough, clearing away heat and toxic materials, relieving spasm and pain, and harmonizing drug properties. It can be used for treating spleen deficiency, asthenia, palpitation, cough, asthma, carbuncle, cellulitis, pharyngitis, abdominal distention, spasm of limbs, and pain. Sweet in taste and neutral in nature; it enters heart, lung and spleen meridians.

Yuzhu, the name of Chinese medicine. Is rhizome of Druce (Polygonatum odoratum (Mill.) Druce) belonging to family Liliaceae, genus Polygonatum. Has effects in nourishing yin, moistening dryness, promoting salivation, and quenching thirst. It can be used for treating cough due to dryness-heat, thirst due to body fluid consumption, exogenous pathogenic factors due to yin deficiency, headache, and fever. Sweet in taste and neutral in nature; it enters lung and stomach meridians.

The name of the Chinese medicine is seville orange flower. Is dried flower mine of Citrus aurantium L.var.amara Eng. Has effects of regulating qi-flowing, relieving chest stuffiness, and stimulating appetite. It can be used for treating chest and abdominal distention, nausea, and anorexia. Mild in nature, sweet and slightly bitter in taste. Chemical components: the leaf and flower of Citrus aurantium L.have aromatic oil content of about 0.2-0.4%, and the pericarp has oil content of about 1.5-2%. The oil comprises the following components: nerol, nerobdol, linalool, etc. about 20 types. Also contains multiple flavonoid glycosides; aurantiamarin, auranetin, heperidine, and the like. The pulp mainly contains citric acid and vitamin C. It is possible that putrescine is contained in the composition with a particular off-flavor. The foreign sour orange variety also contains dipentene, sabinene, myrcene and quinoline alkaloid. The seeds contain fatty oil: mainly comprising oleic acid, linoleic acid and palmitic acid, and a small amount of stearic acid. The pharmacological action is as follows: the seville orange flower herb contains various components of cardiac glycoside and non-cardiac glycoside, and is seen in medicine and food in many countries. The Chinese medicine is called herba Adonidis. It has effects in tonifying heart, promoting urination, tranquilizing mind, and slowing heart rate, and can be used for treating acute diseases and chronic cardiac insufficiency, and can reduce excitability of nervous system and hyperreflexia of spinal cord. It can be used for treating congestive heart failure, cardiac edema and atrial fibrillation, and can be used together with silver bromide for treating epilepsy.

Purslane, the name of traditional Chinese medicine. Is dried aerial part of Portulaca oleracea L.of Portulaca of Portulacaceae. Has the effects of clearing away heat and toxic materials, cooling blood, stopping bleeding, and relieving dysentery. It is mainly used for treating heat-toxin bloody dysentery, heat-toxin sores and ulcers, metrorrhagia and metrostaxis, and hematochezia. Sour and cold in taste; it enters liver and large intestine meridians. Chemical components: the product contains triterpenoid alcohols, flavonoids, amino acids, organic acids and salts thereof, trace elements such as calcium, phosphorus, iron, selenium, potassium nitrate, potassium sulfate and inorganic salts thereof, thiamine, riboflavin, vitamin A, beta-carotene, sucrose, glucose, fructose and the like. The product also contains a large amount of L-noradrenaline and dopamine and a small amount of dopa. The pharmacological action is as follows: the ethanol extract and the water decoction of the product have obvious inhibition effect on dysentery bacillus, and also have certain inhibition effect on escherichia coli, typhoid bacillus, staphylococcus aureus and ozostomia donovani. The fresh juice and boiling water extract can increase the tension of isolated ileum of animal, enhance intestinal peristalsis, and relax colon and duodenum in a dose-dependent manner; the aqueous extract can be administered orally or intraperitoneally to relax skeletal muscle. The extract of the product has obvious effects of resisting oxidation, delaying aging, moistening skin and beautifying. The injection has obvious excitation effect on uterine smooth muscle. The product can increase blood potassium concentration; there was also dose-dependent bidirectional modulation of myocardial contractility. In addition, it also has diuretic and cholesterol lowering effects.

Exocarpium Citri rubrum, named as Chinese medicine. Is dried outer peel of Citrus reticulata Blanco of Rutaceae and its cultivar. Pungent and bitter with warm nature. It enters lung and spleen meridians. The functions are as follows: to regulate qi, relax middle energizer, dry dampness and resolve phlegm. The main treatment is as follows: can be used for treating cough with excessive phlegm, food stagnation, alcohol impairment, nausea, and oppression. Exocarpium Citri rubrum, named as Chinese medicine. Is dried outer peel of Citrus reticulata Blanco of Rutaceae and its cultivar. Harvesting after fruit ripening in late autumn and early winter, cutting off exocarp, and sun drying or shade drying. Pungent and bitter with warm nature. It enters lung and spleen meridians. The functions are as follows: to regulate qi, relax middle energizer, dry dampness and resolve phlegm. The main treatment is as follows: can be used for treating cough with excessive phlegm, food stagnation, alcohol impairment, nausea, and oppression. The book of medical science: tangerine peel, exocarpium Citri rubrum, pungent flavor can move transversely to dissipate nodulation and bitter flavor can move downward directly, is the key herb for promoting qi. For phlegm should be treated by the cap, it is necessary to regulate qi, and qi is good at self-healing, so it enters lung and spleen, and is mainly indicated for all kinds of phlegm diseases. Zhu Ru is used to treat hiccup and help Qing Pi to remove stagnant qi, and is combined with Bai Suo and Ma Huang to dispel food-qi, relieve alcoholism, stop vomiting and open chest and diaphragm stuffiness and plug, so it is pungent, bitter and descending in nature, and it is also used together with cang Zhu and Hou Po to calm stomach and excess, and it is also combined with Bai Su and Ma Huang to dispel food-qi, relieve alcoholism, stop vomiting and open chest and diaphragm stuffiness and plug.

Lalang grass rhizome, name of traditional Chinese medicine. Is the rhizome of Imperata cylindrica Beauv.var.major (Nees) C.E.Hubb. of Imperata genus of Gramineae. Has effects of cooling blood, stopping bleeding, clearing heat, promoting urination, clearing lung-heat and stomach-heat. It can be used for treating hemorrhage due to blood heat, epistaxis, hemoptysis, hematuria, and stranguria with blood, stranguria due to toxic heat, edema, jaundice due to damp-heat, emesis due to stomach heat, and cough and asthma due to lung heat. Sweet in nature and cold in nature; it enters lung, stomach and bladder meridians. A saccharide-containing compound: glucose, sucrose, fructose, xylose, etc., and starch; simple acids and potassium salts: citric acid, malic acid, oxalic acid, and the like; a triterpene: imperatorin, arundol, fernitol, etc.; 5-hydroxytryptamine, and the like; other ingredients also contain carotenoids, chlorophyll, vitamins, and radix Pulsatillae. 1. Effects on the blood nervous system: the cogongrass rhizome can obviously shorten bleeding and blood coagulation time and has the function of stopping bleeding. 2. The antibacterial effect is as follows: has inhibitory effect on pneumococcus, catacoccus, influenzae, Staphylococcus aureus, and Shigella flexneri and Song's dysentery bacillus, and has certain HBV virus resistance. 3. The diuretic effect is: the rhizoma imperatae decoction has the diuretic effect on experimental animals. The rhizoma imperatae decoction of 25g/kg is used for feeding the stomach of the rabbits, and the rabbits have bradykinesia and accelerated respiration after 36 hours, but the rabbits are recovered to be normal soon. LD (traditional Chinese medicine) prepared by performing intragastric administration on mice by adopting rhizoma imperatae decoction₅₀Greater than 160g/kg; LD of mice injected with refined water solution of cogongrass rhizome₅₀The concentration of the mixed solution is 21.42 +/-1.09 g/kg.

Lophatherum gracile, the name of Chinese medicine. Is dried stem and leaf of Lophatherum gracile Brongn of Lophatherum of Gramineae. Has effects of clearing heat-fire, relieving restlessness, and promoting urination. It can be used for treating fever, polydipsia, aphtha, dark urine, pyretic stranguria, and odynuria. Sweet and light taste, cold in nature; it enters heart, stomach and small intestine meridians. The product contains triterpenes such as arundoin, imperatorin, taraxasterol, and steroids such as beta-sitosterol, stigmasterol, campesterol, taraxasterol, etc. The product has antipyretic effect; the product has weak diuretic effect and strong chloride output; the crude extract has anti-tumor effect; the decoction has inhibitory effect on Staphylococcus aureus and hemolytic streptococcus. In addition, it also has blood sugar increasing effect. Lophatherum gracile LD for mice₅₀It was 64.5 g/kg.

Flos sophorae, the name of traditional Chinese medicine. Is dried flower and bud of Sophora japonica L.of Sophora of Leguminosae. Has effects of cooling blood, stopping bleeding, clearing liver-fire and purging pathogenic fire. It can be used for treating hemorrhage due to blood heat, conjunctival congestion, headache, and vertigo due to up-flaming of liver-fire. Bitter taste and slightly cold nature; it enters liver and large intestine meridians. Flos Sophorae Immaturus contains rutin, and has low content after blooming. Triterpene saponin is obtained from dry flower bud, and betulin, sophoricoside diol, glucose and glucuronic acid are obtained after hydrolysis. Flos Sophorae Immaturus extract contains deoxyribose, and C, wherein the deoxyribose is flavone different from rutin, and the B and C are sterols. It also contains quercetin, quercetin tannin, and a large amount of vitamin A substances.

Preferably, the preparation is mainly prepared from the following raw materials in parts by mass:

35-48 parts of green tea, 17-26 parts of ageratum, 17-22 parts of houttuynia cordata, 8-10 parts of lily, 5-8 parts of ginkgo, 25-40 parts of liquorice, 8-10 parts of polygonatum odoratum, 18-22 parts of seville orange flower, 10-13 parts of purslane, 5-9 parts of exocarpium citri rubrum, 13-25 parts of cogongrass rhizome, 20-25 parts of lophatherum gracile and 20-25 parts of sophora flower.

Preferably, the preparation is mainly prepared from the following raw materials in parts by mass:

45 parts of green tea, 24 parts of ageratum, 20 parts of houttuynia cordata, 9 parts of lily, 6 parts of ginkgo, 35 parts of liquorice, 9 parts of polygonatum, 20 parts of seville orange flower, 11 parts of purslane, 7 parts of tangerine peel, 22 parts of lalang grass rhizome, 23 parts of lophatherum gracile and 23 parts of sophora flower.

Preferably, the formulation comprises a powder and/or a spray.

A preparation method of a preparation for promoting nasal obstruction, which comprises the following steps when the preparation is powder: selecting green tea, ageratum, houttuynia cordata, lily, ginkgo, liquorice, polygonatum, seville orange flower, purslane, red tangerine peel, lalang grass rhizome, lophatherum gracile and sophora flower according to a corresponding proportion, mixing, grinding and filtering to obtain a finished product.

A preparation method of a preparation for promoting nasal obstruction comprises the following steps when the preparation is a spray: selecting green tea, ageratum, houttuynia cordata, lily, ginkgo, liquorice, polygonatum, seville orange flower, purslane, red tangerine peel, lalang grass rhizome, lophatherum gracile and sophora flower according to a corresponding proportion, mixing, decocting and filtering to obtain a finished product.

Preferably, after the grinding, each raw material powder has a particle diameter of 10 to 30 μm.

Preferably, the solvent added during the decoction is water,

the weight ratio of the total weight of the green tea, the ageratum, the houttuynia cordata, the lily, the ginkgo, the liquorice, the polygonatum odoratum, the seville orange flower, the purslane, the red tangerine peel, the lalang grass rhizome, the lophatherum gracile and the sophora flower to the decocting solvent is 1-3: 5-12.

Preferably, the decoction temperature is 70-100 ℃.

Preferably, the decoction period is 45-85 minutes.

The invention has the beneficial effects that:

the invention provides a preparation which is helpful for smoothing nose, and the preparation uses green tea to clear heat, improve eyesight, sterilize and diminish inflammation; ageratum, mild in nature, pungent and sweet in flavor, fragrant in flavor, resolving turbidity, regulating the middle warmer, arresting vomiting, relieving exterior syndrome, relieving summer-heat and sterilizing; the houttuynia cordata is pungent in taste and slightly cold in nature, has the effects of clearing away heat and toxic materials, inhibiting bacteria, removing heat, resisting viruses and inflammation and improving immunity; lily is sweet in taste and slightly cold in nature, enters lung, heart and stomach channels, and has the effects of nourishing yin and moistening lung; gingko is sweet, bitter and astringent in taste and mild in nature; entering lung and kidney meridians, astringing lung and relieving asthma; licorice, sweet in taste, neutral in nature; the traditional Chinese medicine composition has the effects of invigorating qi and strengthening middle warmer, nourishing lung and relieving cough, clearing away heat and toxic materials, and regulating drug properties; yu Zhu is sweet in flavor and neutral in nature; enter lung and stomach meridians, nourish yin and moisten dryness; the bitter orange flower has mild nature, sweet and slightly bitter taste, and can regulate qi and relieve chest stuffiness; purslane, sour and cold in taste; the Chinese medicinal composition belongs to liver and large intestine channels, and has the effects of clearing away heat and toxic materials, inhibiting bacteria and diminishing inflammation; ju hong, pungent and bitter in flavor and warm in nature. Enter lung and spleen channels, regulate qi to relieve epigastric distention, dry dampness and resolve phlegm; cogongrass rhizome, sweet in nature, cold in nature; the medicine belongs to the channels of lung, stomach and bladder, and has the effects of clearing heat, promoting urination, clearing lung and stomach heat and resisting bacteria; lophatherum gracile, sweet and light in flavor, cold in nature; the medicine has the functions of clearing heat, purging fire and inhibiting bacteria, and enters heart, stomach and small intestine channels; flos sophorae, bitter in taste, slightly cold in nature; it enters liver and large intestine channels, and has effects of clearing liver-fire and is rich in vitamins. The raw materials are all Chinese herbal medicines which are neutral in nature and sweet in taste and mainly enter lung and spleen channels, and the components are mild and harmonized, so that the nasal suppository can relieve nasal obstruction, clear away heat and toxic materials, resist bacteria and diminish inflammation, and has a good auxiliary effect on various nasal inflammations.

The preparation method of the preparation adopts two preparation modes to obtain two preparation finished products, and the two preparation finished products have the advantages of simple preparation method, convenient use and transportation, long storage time, no toxic or side effect, and no irritation.

Detailed Description

The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. The reagents used are all conventional products which are commercially available.

Example 1:

a preparation method of powder for helping nose unobstructed comprises the following steps: selecting 30 g of green tea, 15 g of ageratum, 15 g of houttuynia cordata, 6 g of lily, 3 g of ginkgo, 20 g of liquorice, 6 g of polygonatum, 13 g of seville orange flower, 9g of purslane, 3 g of red tangerine peel, 10 g of lalang grass rhizome, 16 g of lophatherum gracile and 15 g of sophora flower according to corresponding proportion, mixing and grinding, and filtering all the raw material powder with the particle size of 10 mu m to obtain a finished product.

Example 2:

a preparation method of powder for helping nose unobstructed comprises the following steps: selecting 50 g of green tea, 30 g of ageratum, 25g of houttuynia cordata, 12 g of lily, 9g of ginkgo, 46 g of liquorice, 12 g of polygonatum, 25g of seville orange flower, 15 g of purslane, 10 g of red tangerine peel, 30 g of lalang grass rhizome, 29 g of lophatherum gracile and 30 g of sophora flower according to corresponding proportion, mixing and grinding, and filtering all the raw material powder with the particle size of 30 mu m to obtain a finished product.

Example 3:

a preparation method of powder for helping nose unobstructed comprises the following steps: according to the corresponding proportion, 35 g of green tea, 17 g of ageratum, 17 g of houttuynia cordata, 8 g of lily, 5g of ginkgo, 25g of liquorice, 8 g of polygonatum, 18 g of seville orange flower, 10 g of purslane, 5g of red tangerine peel, 13 g of lalang grass rhizome, 20 g of lophatherum gracile and 20 g of sophora flower are selected, mixed and ground, and all the raw material powder with the particle size of 10 mu m is filtered to obtain the finished product.

Example 4:

a preparation method of powder for helping nose unobstructed comprises the following steps: selecting 48 g of green tea, 26 g of ageratum, 22 g of houttuynia cordata, 10 g of lily, 8 g of ginkgo, 40 g of liquorice, 10 g of polygonatum odoratum, 22 g of seville orange flower, 13 g of purslane, 9g of red tangerine peel, 25g of lalang grass rhizome, 25g of lophatherum gracile and 25g of sophora flower according to corresponding proportion, mixing and grinding, and filtering all the raw material powder with the particle size of 30 mu m to obtain a finished product.

Example 5:

a preparation method of powder for helping nose unobstructed comprises the following steps: according to the corresponding proportion, 45 g of green tea, 24 g of ageratum, 20 g of houttuynia cordata, 9g of lily, 6 g of ginkgo, 35 g of liquorice, 9g of polygonatum, 20 g of seville orange flower, 11 g of purslane, 7 g of red tangerine peel, 22 g of lalang grass rhizome, 23 g of lophatherum gracile and 23 g of sophora flower are selected, mixed and ground, and all the raw material powder with the particle size of 30 mu m is filtered to obtain the finished product.

The final product obtained in examples 1-5 above is a powder which can be used by keeping in snuff bottle or related container and then inhaling through the nose.

Example 6:

a preparation method of a spray for promoting nasal obstruction comprises the following steps: selecting 30 g of green tea, 15 g of ageratum, 15 g of houttuynia cordata, 6 g of lily, 3 g of ginkgo, 20 g of liquorice, 6 g of polygonatum odoratum, 13 g of seville orange flower, 9g of purslane, 3 g of exocarpium citri rubrum, 10 g of lalang grass rhizome, 16 g of lophatherum gracile and 15 g of sophora flower according to corresponding proportion, mixing, adding 805 g of water, decocting for 45 minutes at 70 ℃, and filtering to obtain a finished product.

Example 7:

a preparation method of a spray for promoting nasal obstruction comprises the following steps: according to the corresponding proportion, 50 g of green tea, 30 g of ageratum, 25g of houttuynia cordata, 12 g of lily, 9g of ginkgo, 46 g of liquorice, 12 g of polygonatum, 25g of seville orange flower, 15 g of purslane, 10 g of red tangerine peel, 30 g of lalang grass rhizome, 29 g of lophatherum gracile and 30 g of sophora flower are selected, mixed, added with 1292 g of water, decocted for 85 minutes at 100 ℃ and filtered to obtain the finished product.

Example 8:

a preparation method of a spray for promoting nasal obstruction comprises the following steps: according to the corresponding proportion, 35 g of green tea, 17 g of ageratum, 17 g of cordate houttuynia, 8 g of lily, 5g of ginkgo, 25g of liquorice, 8 g of polygonatum, 18 g of seville orange flower, 10 g of purslane, 5g of red tangerine peel, 13 g of lalang grass rhizome, 20 g of lophatherum gracile and 20 g of sophora flower are selected, mixed, added with 1005 g of water, decocted for 45 minutes at 100 ℃ and filtered to obtain the finished product.

Example 9:

a preparation method of a spray for promoting nasal obstruction comprises the following steps: according to the corresponding proportion, 48 g of green tea, 26 g of ageratum, 22 g of houttuynia cordata, 10 g of lily, 8 g of ginkgo, 40 g of liquorice, 10 g of polygonatum, 22 g of seville orange flower, 13 g of purslane, 9g of red tangerine peel, 25g of lalang grass rhizome, 25g of lophatherum gracile and 25g of sophora flower are selected, mixed, added with 1415 g of water, decocted for 85 minutes at 70 ℃ and filtered to obtain the finished product.

Example 10:

a preparation method of a spray for promoting nasal obstruction comprises the following steps: according to the corresponding proportion, 45 g of green tea, 24 g of ageratum, 20 g of houttuynia cordata, 9g of lily, 6 g of ginkgo, 35 g of liquorice, 9g of polygonatum, 20 g of seville orange flower, 11 g of purslane, 7 g of red tangerine peel, 22 g of lalang grass rhizome, 23 g of lophatherum gracile and 23 g of sophora flower are selected, mixed, added with 1016 g of water, decocted for 85 minutes at 70 ℃ and filtered to obtain the finished product.

The finished product obtained in the above examples 6-10 is a spray which can be sprayed into the nasal cavity by placing in a spray can, adhering to the nasal cavity wall and nasal mucosa, and then enter the patient by penetration.

The present invention is not limited to the above alternative embodiments, and any other products in various forms can be obtained by the present invention, and the present invention is within the protection scope of the present invention. The above embodiments should not be construed as limiting the scope of the present invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the above embodiments, or equivalent substitutions may be made to some or all of the technical features thereof, without departing from the scope of the present invention, and at the same time, such modifications or substitutions may not make the essence of the corresponding technical solutions depart from the scope of the embodiments of the present invention.

Claims (10)

1. The preparation for promoting nasal obstruction is characterized by being prepared from the following raw materials in parts by mass:

30-50 parts of green tea, 15-30 parts of ageratum, 15-25 parts of houttuynia cordata, 6-12 parts of lily, 3-9 parts of ginkgo, 20-46 parts of liquorice, 6-12 parts of polygonatum odoratum, 13-25 parts of seville orange flower, 9-15 parts of purslane, 3-10 parts of exocarpium citri rubrum, 10-30 parts of lalang grass rhizome, 16-29 parts of lophatherum gracile and 15-30 parts of sophora flower.

2. The preparation for promoting nasal obstruction of claim 1, wherein the preparation is prepared from the following raw materials in parts by mass:

35-48 parts of green tea, 17-26 parts of ageratum, 17-22 parts of houttuynia cordata, 8-10 parts of lily, 5-8 parts of ginkgo, 25-40 parts of liquorice, 8-10 parts of polygonatum odoratum, 18-22 parts of seville orange flower, 10-13 parts of purslane, 5-9 parts of exocarpium citri rubrum, 13-25 parts of cogongrass rhizome, 20-25 parts of lophatherum gracile and 20-25 parts of sophora flower.

3. The preparation for promoting nasal obstruction of claim 2, wherein the preparation is prepared from the following raw materials in parts by mass:

45 parts of green tea, 24 parts of ageratum, 20 parts of houttuynia cordata, 9 parts of lily, 6 parts of ginkgo, 35 parts of liquorice, 9 parts of polygonatum, 20 parts of seville orange flower, 11 parts of purslane, 7 parts of tangerine peel, 22 parts of lalang grass rhizome, 23 parts of lophatherum gracile and 23 parts of sophora flower.

4. A formulation for promoting nasal patency according to any of claims 1-3, wherein the formulation comprises a powder and/or a spray.

5. A method of preparing a formulation for promoting nasal patency as claimed in any of claims 1 to 4, wherein when the formulation is a powder, the method comprises the steps of: selecting green tea, ageratum, houttuynia cordata, lily, ginkgo, liquorice, polygonatum, seville orange flower, purslane, red tangerine peel, lalang grass rhizome, lophatherum gracile and sophora flower according to a corresponding proportion, mixing, grinding and filtering to obtain a finished product.

6. A method of preparing a formulation as claimed in any one of claims 1 to 4, for promoting nasal patency, wherein when the formulation is a spray, the method comprises the steps of: selecting green tea, ageratum, houttuynia cordata, lily, ginkgo, liquorice, polygonatum, seville orange flower, purslane, red tangerine peel, lalang grass rhizome, lophatherum gracile and sophora flower according to a corresponding proportion, mixing, decocting and filtering to obtain a finished product.

7. The method for preparing a preparation for promoting nasal patency according to claim 5, wherein after the grinding, each raw material powder has a particle size of 10-30 μm.

8. The method of claim 6, wherein the solvent added during the decoction is water,

the weight ratio of the total weight of the green tea, the ageratum, the houttuynia cordata, the lily, the ginkgo, the liquorice, the polygonatum odoratum, the seville orange flower, the purslane, the red tangerine peel, the lalang grass rhizome, the lophatherum gracile and the sophora flower to the decocting solvent is 1-3: 5-12.

9. The method of claim 6, wherein the decocting temperature is 70-100 ℃.

10. The method of claim 9, wherein the decocting is for 45-85 minutes.