CN105943940A - Traditional Chinese medicine for treating allergic rhinitis and preparation method of preparation thereof - Google Patents
Traditional Chinese medicine for treating allergic rhinitis and preparation method of preparation thereof Download PDFInfo
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- CN105943940A CN105943940A CN201610572459.8A CN201610572459A CN105943940A CN 105943940 A CN105943940 A CN 105943940A CN 201610572459 A CN201610572459 A CN 201610572459A CN 105943940 A CN105943940 A CN 105943940A
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Abstract
A traditional Chinese medicine for treating allergic rhinitis is prepared from 1-60 parts of astragalus membranaceus, 1-30 parts of white atractylodes rhizome, 1-20 parts of saposhnicovia divaricate, 1-20 parts of the fruits of Chinese magnoliavine, 1-30 parts of the seeds of Chinese dodder, 1-6 parts of asarum, 1-20 parts of madder, 1-30 parts of indian epimeredi herb, 1-20 parts of periostracum cicada, 1-20 parts of smoked plums, 1-30 parts of lumbricus, 1-30 parts of Eclipta alba, 1-30 parts of light wheat and 1-20 parts of radix glycyrrhizae. The dosage form of the medicine is decoctum, powder, capsules, tablets, granules or pills. The monarch, subject, assistant and adjuvant materials are brought into play, and the medicine has the advantages that little medicine is adopted, the medicine becomes effective rapidly, and clinical observation verifies that no toxic or side effect exists.
Description
Technical field
The present invention relates to the preparation method of a kind of Chinese medicine composition and preparation thereof for treating allergic rhinitis, belong to tcm field.
Background technology
Allergic rhinitis i.e. allergic rhinitis, after referring to atopic individuals contact allergen, medium (mainly histamine) release mainly mediated by IgE, and have the nasal mucosa non-infectious inflammatory disease of the participations such as panimmunity competent cell and cytokine.Its essential condition occurred has 3: specific antigen i.e. causes the material of organism immune response；Atopic individuals the most so-called individual variation, allergic constitution；Specific antigen and spy answer both type individualities to meet.Allergic rhinitis are global health problem, may result in numerous disease and disability.Allergic rhinitis are a kind of multi-factor diseases being interacted by gene and environment and being induced.The risk factor of allergic rhinitis is likely to be present in all age brackets.Allergic rhinitis patients has atopy body constitution, generally demonstrates familial aggregation.Allergen is inducing specific IgE antibody the antigen reacted therewith, and allergen is broadly divided into inhalant allergen and food-consuming structure, and inhalant allergen is the main cause of allergic rhinitis.Clinical manifestation is mainly paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and rhinocnesmus.Part is with hyposmia.Treatment is except avoiding contact with allergen, and also Drug therapy, the most conventional intranasal and oral administration, severe patient may select surgical intervention.Oral administration Western medicine mostly is antihistaminic, glucocorticoid, anti-leukotriene medicine, intranasal Decongestant.Part Chinese medicine is effective to relief of symptoms.Having the medicine such as BIYANKANG, rhinitis tablet clinically, shortcoming is weak curative effect, does not has preferable therapeutic effect to allergic rhinitis.Effect is undesirable, the most repeatedly, the present invention is directed to cause of disease onset, and allergic rhinitis need not be performed the operation, and curative effect is certainly.
Summary of the invention
For the deficiencies in the prior art, the present invention provides a kind of and treats sick Chinese medicine composition of allergic rhinitis and preparation method thereof.
Technical scheme is as follows:
A kind of Chinese medicine composition treating allergic rhinitis, is made up of the raw material of following weight portion:
Radix Astragali 1-60 part, Rhizoma Atractylodis Macrocephalae 1-30 part, Radix Saposhnikoviae 1-20 part, Fructus Schisandrae Chinensis 1-20 part, Semen Cuscutae 1-30 part, Herba Asari 1-6 part, Radix Rubiae 1-20 part, label grass 1-30 part, Periostracum Cicadae 1-20 part, Fructus Mume 1-20 part, Pheretima 1-30 part, Herba Ecliptae 1-30 part, Fructus Tritici Levis 1-30 part, Radix Glycyrrhizae 1-20 part.
Further preferred as above-mentioned technology case, described Chinese medicine composition is made up of the raw material of following weight portion:
The Radix Astragali 30 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Saposhnikoviae 10 parts, Fructus Schisandrae Chinensis 10 parts, Semen Cuscutae 15 parts, Herba Asari 3 parts, 15 parts of Radix Rubiae, label grass 15 parts, Periostracum Cicadae 15 parts, Fructus Mume 15 parts, Pheretima 15 parts, Herba Ecliptae 15 parts, Fructus Tritici Levis 15 parts, 10 parts of Radix Glycyrrhizae.
According to the present invention, the preparation method of a kind of Chinese medicinal composition preparation treating allergic rhinitis, comprise the following steps:
A, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Fructus Schisandrae Chinensis, Semen Cuscutae, Herba Asari, Radix Rubiae, label grass, Periostracum Cicadae, Fructus Mume, Pheretima, Herba Ecliptae, Fructus Tritici Levis, Radix Glycyrrhizae are mixed together, boiling twice, filters, merging filtrate, it is concentrated into the 1/2 of filtrate volume, obtains concentrated solution；
B, the concentrated solution of step a gained is concentrated into relative density 80 DEG C records the thick extractum of 1.20～1.24；
C, baking oven after the thick extractum mix homogeneously of above-mentioned steps b, will be moved into, and dry to moisture less than 5% for 50-70 DEG C, add adjuvant and make powder, capsule, tablet, granule or pill by prior art.
According to the present invention, the preparation method of a kind of Chinese medicinal composition preparation treating allergic rhinitis, including taking each material composition in proportion, mixing, boiling 30 minutes, become water decoction.
Described Chinese medicine composition pharmaceutical dosage form is: water decoction, powder, capsule, tablet, granule or pill.
In above raw material:
The Radix Astragali: sweet in the mouth slightly warm in nature.Return lung, spleen, liver, kidney channel.Polishing consolidating superficial resistance, holds in the palm skin ulcer granulation promoting.Curing mainly body void spontaneous perspiration, chronic diarrhea, proctoptosis, uterine prolapse, chronic nephritis, body is impractical swollen, chronic ulcer, the long disunion of the open sore part.
The Rhizoma Atractylodis Macrocephalae: spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive.Controlling deficient QI of the spleen and stomach, anorexia, the few gas of asthenia, deficiency-distension, have loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizzy, spontaneous perspiration, nausea is uneasy.
Radix Saposhnikoviae: Radix Saposhnikoviae acrid in the mouth, sweet, slightly warm in nature；Return lung, spleen, liver, bladder warp；Gas perfume (or spice) rises and dissipates；There is expelling pathogenic wind from the body surface, removing damp and stopping pain, soothing the liver spasmolytic, effect of killing parasites for relieving itching；Cure mainly affection of exogenous wind-cold, stiffness of the nape of having a headache, dizzy dusk is puckery, anemofrigid-damp arthralgia, and joint is ached, and stomachache is had loose bowels, discharging fresh blood stool, broken damaging the spleen and stomach wind, and measles is difficult thoroughly, rubella pruritus, skin infection from the beginning of.
Fructus Schisandrae Chinensis: sweet in the mouth, acid, warm in nature.Energy supplementing QI for promoting the production of body fluid, the kidney invigorating is nourished heart, and restrains astringent or styptic treatment for spontaneous sweating.Hinder for deficiency of vital energy Tianjin, the tired hyperhidrosis of body, cardiopalmus of losing heart；Breathing with cough caused by insufficiency of lung-QI or deficiency of both the lung and kidney, or breath with cough with the passing of time, lung qi consumption wound；Insufficiency of heart-YIN, severe palpitation, insomnia forgetfulness；Instability of kidney QI, seminal emission, frequent micturition, or asthenia of both the spleen and kidney.
Semen Cuscutae: nourishing the liver and kidney, antiabortive, improving eyesight, antidiarrheal.For: impotence and seminal emission, dripping urination, enuresis frequent micturition, medicine knees soreness, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down.
Herba Asari: dispel the wind, cold expelling, row water, have one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Preferably lead to lung key: for rhinitis, sinusitis
Radix Rubiae: bitter, cold.Return Liver Channel.There are cooling blood for hemostasis, blood stasis dispelling, the effect stimulated the menstrual flow.Cure mainly heat in blood and tell nosebleed, metrostaxis, blood stasis amenorrhea, traumatic injury, rheumatic arthralgia.Owing to Radix Rubiae has the effect of promoting blood circulation to restore menstrual flow, it is commonly used to clinically treat rheumatic arthralgia.
Sign careless: remove rheumatism, strong muscles and bones, heat-clearing and toxic substances removing.Control quadriplegia, bones and muscles pain, weakness of the waist and knees, malaria, acute hepatitis, hypertension, furuncle swelling toxin, traumatic hemorrhage.
Periostracum Cicadae: Periostracum Cicadae can dissipate wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Fructus Mume: sour in the mouth, micro-puckery, property is put down.Return liver, spleen, lung, stomach, large intestine channel.Matter profit is held back puckery.Astringe the lung, astringing intestine to stop diarrhea, promote the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat quenches one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.
Pheretima: Pheretima is cold in nature, salty in the mouth.Function: heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral.Return liver, stomach, lung, bladder warp.Function heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, relieving asthma, diuresis, dredging collateral eliminating impediment.Cure mainly the cards such as high heat agitation, infantile convulsion tic, dyspnea and cough due to lung-heat, accumulation of heat urine retention, arthralgia pain limb fiber crops, hemiplegia, and sore swollen toxin.Cure mainly high fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, hemiplegia etc..Pheretima provides and takes liquid and have and good determine the effect that cloperastine is breathed heavily.
Herba Ecliptae: nourishing the liver and kidney, crow palpus teeth consolidating, cooling blood for hemostasis.Curing mainly: deficiency of the liver and kindey, vertigo and tinnitus, blurring of vision, soreness of the waist and knees, turn white luxated tooth, stranguria caused by overstrain foul leukorrhea, spitting of blood, spits blood, epistaxis, hematuria, dysentery, metrorrhagia, traumatic hemorrhage.
Fructus Tritici Levis: nature and flavor are sweet, cool, enter heart channel, has QI invigorating heat extraction, nourishes heart and promote the production of body fluid, only sweating due to debility, night sweat, the effect of hectic fever due to YIN-deficiency deficiency-heat, is used for treating deficiency-heat hyperhidrosis, night sweat, dry mouth and tougue, vexed insomnia.
Radix Glycyrrhizae: Radix Glycyrrhizae property is put down, sweet in the mouth returns 12 warps.Have removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, to grow and cough lung moistening, emergency is detoxified, and is in harmonious proportion hundred medicines.
The allergic rhinitis traditional Chinese medical science belongs to " nasal sinusitis ", is because heresy violates nasal sinuses, damp and hot in hole accumulates long-pending, and it is turbid caused to lead to expectorant, the cacorhinia being characterized with turbid nasal discharge amount more.Syndrome-classification is wind and heat in the lung meridian, gallbladder heat stagnation, damp-heat in the spleen and stomach, asthenia of pulmonosplenic qi.The present invention application Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae benefiting QI for strengthening the superficies, mainly treat the asthenia of pulmonosplenic qi of allergic rhinitis.Semen Cuscutae, Fructus Tritici Levis, Herba Ecliptae nourishing the liver and kidney consolidating superficial resistance.Pheretima, Periostracum Cicadae heat clearing away suppressing the hyperactive liver, scattered wind heat extraction, mainly treat the gallbladder heat stagnation of allergic rhinitis.Sign grass, Herba Asari coordinates Periostracum Cicadae mainly to treat the wind and heat in the lung meridian of allergic rhinitis.Herba Asari, Radix Rubiae, Fructus Mume are astringed the lung tears, and promoting blood circulation to restore menstrual flow, for the nasal mucosa congested treatment for a long time of allergic rhinitis.Monarch, minister, help, make respectively to execute its effect, evident in efficacy.
The present invention uses above technical scheme, compared with prior art, has the advantage that purchase is convenient, low price, raw material each component proportion example is reasonable, action compensating, organic compatibility, monarch of the present invention, minister, helps, makes respectively to execute its effect, has medication few, instant effect, clinical observation confirms to have no side effect, and can reach the purpose of giving consideration to both the incidental and fundamental, and therapeutic effect is good, without the toxic and side effects of chemicals, can long-term taking.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1: a kind of Chinese medicine composition for treating allergic rhinitis, is made up of the raw material of following weight portion:
The Radix Astragali 30 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Saposhnikoviae 10 parts, Fructus Schisandrae Chinensis 10 parts, Semen Cuscutae 15 parts, Herba Asari 3 parts, 15 parts of Radix Rubiae, label grass 15 parts, Periostracum Cicadae 15 parts, Fructus Mume 15 parts, Pheretima 15 parts, Herba Ecliptae 15 parts, Fructus Tritici Levis 15 parts, 10 parts of Radix Glycyrrhizae.
Preparation method, comprises the following steps:
A, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Fructus Schisandrae Chinensis, Semen Cuscutae, Herba Asari, Radix Rubiae, label grass, Periostracum Cicadae, Fructus Mume, Pheretima, Herba Ecliptae, Fructus Tritici Levis, Radix Glycyrrhizae are mixed together, boiling twice, filters, merging filtrate, it is concentrated into the 1/2 of filtrate volume, obtains concentrated solution；
B, the concentrated solution of step a gained is concentrated into relative density 80 DEG C records the thick extractum of 1.20～1.24；
C, baking oven after the thick extractum mix homogeneously of above-mentioned steps b, will be moved into, and dry to moisture less than 5% for 50-70 DEG C, add adjuvant and make powder by prior art.
Embodiment 2: a kind of Chinese medicine composition for treating allergic rhinitis, is made up of the raw material of following weight portion:.
The Radix Astragali 60 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Radix Saposhnikoviae 20 parts, Fructus Schisandrae Chinensis 20 parts, Semen Cuscutae 30 parts, Herba Asari 6 parts, 20 parts of Radix Rubiae, sign grass 30 parts, Periostracum Cicadae 20 parts, Fructus Mume 20 parts, Pheretima 30 parts, Herba Ecliptae 30 parts, Fructus Tritici Levis 30 parts, 20 parts of Radix Glycyrrhizae.
Preparation method is with embodiment 1.
Embodiment 3: a kind of Chinese medicine composition for treating allergic rhinitis, is made up of the raw material of following weight portion:
The Radix Astragali 15 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Radix Saposhnikoviae 6 parts, Fructus Schisandrae Chinensis 6 parts, Semen Cuscutae 8 parts, Herba Asari 2 parts, 8 parts of Radix Rubiae, label grass 8 parts, Periostracum Cicadae 8 parts, Fructus Mume 8 parts, Pheretima 8 parts, Herba Ecliptae 8 parts, Fructus Tritici Levis 8 parts, 6 parts of Radix Glycyrrhizae.
Preparation method is with embodiment 1.
Contrast test:
Criterion of therapeutical effect: according to the curative effect determinate standard for the treatment of " nasal sinusitis " in<<TCM E.N.T. Dept. disease Standardization of diagnosis and curative effect>>:
Efficacy evaluation:
Cure: transference cure, x-ray nasal sinuses sheet is without exception.
Taking a turn for the better: symptom is obviously improved, nasal cavity inspection is shown in that the performance such as hyperemia, mucosa swelling alleviates.X-ray nasal sinuses is taken the photograph sheet and is had clear improvement.
Do not heal: sings and symptoms is without improving.
Choose the Allergic Rhinitis of 200 examples, randomly select 150 examples as treatment group, other 50 examples are as a control group, wherein 150 example patients are divided into treatment group 1, treatment group 2 and treatment group 3, each treatment group treats the 50 example patients randomly selected, the powder that treatment group 1 uses the embodiment of the present invention 1 to prepare is treated, and the powder that treatment group 2 uses the embodiment of the present invention 2 to prepare is treated, and the powder that treatment group 3 uses the embodiment of the present invention 3 to prepare is treated.The control group BIYANKANG is treated.It within one month, it was 1 course for the treatment of.
Therapeutic outcome such as following table:
From data above table it can be seen that treatment group effective percentage cure rate is higher than remaining treatment group apparently higher than matched group, the cure rate effective percentage for the treatment of group 1 and 2, treatment group in sum 1 and 2 prescription is maximally efficient.
Claims (3)
1. treat a Chinese medicine composition for allergic rhinitis, it is characterized in that: described Chinese medicine composition is made up of the raw material of following weight portion:
Radix Astragali 1-60 part, Rhizoma Atractylodis Macrocephalae 1-30 part, Radix Saposhnikoviae 1-20 part, Fructus Schisandrae Chinensis 1-20 part, Semen Cuscutae 1-30 part, Herba Asari 1-6 part, Radix Rubiae 1-20 part, label grass 1-30 part, Periostracum Cicadae 1-20 part, Fructus Mume 1-20 part, Pheretima 1-30 part, Herba Ecliptae 1-30 part, Fructus Tritici Levis 1-30 part, Radix Glycyrrhizae 1-20 part.
2. treat the Chinese medicine composition of allergic rhinitis as claimed in claim 1, it is characterized in that: described Chinese medicine composition is made up of the raw material of following weight portion:
The Radix Astragali 30 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Saposhnikoviae 10 parts, Fructus Schisandrae Chinensis 10 parts, Semen Cuscutae 15 parts, Herba Asari 3 parts, 15 parts of Radix Rubiae, label grass 15 parts, Periostracum Cicadae 15 parts, Fructus Mume 15 parts, Pheretima 15 parts, Herba Ecliptae 15 parts, Fructus Tritici Levis 15 parts, 10 parts of Radix Glycyrrhizae.
3. treat the preparation method of the Chinese medicinal composition preparation of allergic rhinitis as claimed in claim 1 or 2, it is characterized in that: described preparation method comprises the following steps:
A, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Fructus Schisandrae Chinensis, Semen Cuscutae, Herba Asari, Radix Rubiae, label grass, Periostracum Cicadae, Fructus Mume, Pheretima, Herba Ecliptae, Fructus Tritici Levis, Radix Glycyrrhizae are mixed together, boiling twice, filters, merging filtrate, it is concentrated into the 1/2 of filtrate volume, obtains concentrated solution；
B, the concentrated solution of step a gained is concentrated into relative density 80 DEG C records the thick extractum of 1.20～1.24；
C, baking oven after the thick extractum mix homogeneously of above-mentioned steps b, will be moved into, and dry to moisture less than 5% for 50-70 DEG C, add adjuvant and make powder, capsule, tablet, granule or pill by prior art.
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