CN105106508A

CN105106508A - Cocklebur fruit allergic rhinitis paste

Info

Publication number: CN105106508A
Application number: CN201510638836.9A
Authority: CN
Inventors: 朱家奎
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-10-08
Filing date: 2015-10-08
Publication date: 2015-12-02

Abstract

The invention discloses cocklebur fruit allergic rhinitis paste, and belongs to the field of Chinese pharmaceutical manufacturing. The medicine is prepared by virtue of the following Chinese herbs: cocklebur fruits, herba centipedae, Chinese ephedra, periostracum cicada, radix saposhnikoviae, cinnamon, notopterygium root, asarum heterotropoides, nidus vespae, semen brassicae, radix angelicae dahuricae, magnolia liliflora, spina gleditsiae, rhizoma acori graminei, scutellaria baicalensis, herba schizonepetae, rhizoma atractylodis, pinellia ternate, astragalus mongholicus, white atractylodes rhizome and poria cocos. The cocklebur fruit allergic rhinitis paste is mainly used for treating diseases such as allergic rhinitis. The cocklebur fruit allergic rhinitis paste has the functions of replenishing Qi and strengthening the superficies, facilitating the flow of lung-qi, invigorating the spleen, removing the dampness, warming the lung, dispelling the coldness, clearing away the internal heat and removing the toxicity; the general efficiency is 95 percent, the healing rate is 70 percent, one course of treatment is needed for healing, 2 to 3 courses of treatment are needed for patients with severe syndromes, and the market development prospect is relatively good (one month is a course of treatment).

Description

Fructus Xanthii allergic rhinitis cream

Technical field

The present invention relates to a kind of Fructus Xanthii allergic rhinitis cream, belong to field of traditional Chinese medicine pharmacy.

Background technology

The medium of allergic rhinitis mainly IgE mediation after referring to atopic individuals contact allergen discharges, and has the nasal mucosa noninfectious disease that panimmunity competent cell and cytokine etc. participate in.Its essential condition occurred has following three: 1: namely specific antigen causes the material of organism immune response; 2: specificity individuality and so-called individual variation, anaphylaxis material; 3: specific antigen and spy answer both type individualities to meet.It shows as nasal decongestion swelling, recurrent exerbation, sneeze, stream clear water sample nasal mucus, and nose is itched, and severe patient eyes, ear are red itches.Motherland's traditional medicine think allergic rhinitis main with lung, the dirty void of spleen, kidney three is relevant, how because of insufficiency of lung-QI, be affected by the cold, deficiency of kidney-QI caused, common lung qi deficiency and coldness, deficiency-weakness of spleen-QI, kidney qi weakness.Though currently available technology has the routine of multiple treatment of allergic rhinitis to take orally or the medicine of external, mostly poor effect or take effect slow, Western medicine side effect is large simultaneously, and only take stopgap measures, do not effect a permanent cure, curative effect is general.

Summary of the invention

The technical barrier that side effect is large and relapse rate is high that the medicine that the object of the invention is to improve existing treatment of allergic rhinitis exists also provides a kind of effective, short treating period, price are low, cure rate is high a kind of Fructus Xanthii allergic rhinitis cream.The present invention cures mainly: the diseases such as allergic rhinitis, the present invention has invigorating QI to consolidate the body surface resistance, lung qi dispersing is regulated the flow of vital energy, effect of replenishing QI to invigorate the spleen dampness removing, warming lung for dispelling cold, heat-clearing and toxic substances removing, total effective rate 95%, cure rate 70%, average healing needs 1 course for the treatment of, and the person of being in a bad way needs 2-3 the course for the treatment of.(January is a course for the treatment of)

The present invention is the technical scheme adopted that solves the problem:

Fructus Xanthii allergic rhinitis cream, its preparation method: by the drying respectively of above medicine, roguing, the process of preparing Chinese medicine, then be ground into smalls with pulverizer, cross 120 mesh sieves for subsequent use, subsequently medicated powder is mixed homogeneously according to a conventional method paste making agent with appropriate lanoline, glycerol.

Pharmacological property is analyzed: Fructus Xanthii, for the fruit of the drying and ripening band involucre of feverfew Herba Xanthii eats, gather during fruit maturation in autumn, dry, go out the impurity such as destemming leaf, the bitter temperature of acrid in the mouth, poisonous, enter lung meridian, there is expelling pathogenic wind from the body surface, a surname's clearing the nasal passage, removing damp and stopping pain, for headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture, while main expelling pathogenic wind from the body surface controls primary symptom, the special work of energy is in clearing the nasal passage, the stubbornness removed in this exterior syndrome is held concurrently disease, and its can removing damp and stopping pain, and treatment affection of exogenous wind-cold is held concurrently the disease of the tired resistance of folder damp; Herba Centipedae, be the dry herb of feverfew Herba Centipedae, the autumn in summer two gathers when season, the flowers are in blossom, washes away silt, dry, acrid in the mouth is warm in nature, enters lung Liver Channel, there is clearing the nasal passage, cough-relieving, for headche due to wind-cold, cough with copious phlegm, has a stuffy nose obstructed, nasal sinusitis watery nasal discharge, can also preventing phlegm from forming and stopping coughing, time symptom of holding concurrently in treatment exterior syndrome, expectorant, cough, breathe heavily, be applicable to controlling that exterior syndrome is double invades and the disease of upper lower respiratory tract; Herba Ephedrae, be the herb stem of Ephedraceae plant plait Herba Ephedrae, ephedra equisetina or Herba Ephedrae, bitter in the mouth temperature, enters lung urinary bladder channel, diaphoresis, relievings asthma, effect of diuretic, controls the diseases such as fever with chills is lossless, headache nasal obstruction, joint pain; " the southern regions of the Yunnan Province book on Chinese herbal medicine ": control that nose key nasal obstruction is obstructed, good and foul smells does not hear, lung cold cough; Periostracum Cicadae, be the shell after the emergence of cicada Cryptotympana atrata Fabr., sweet-salty is cool in nature, enters liver spleen lung meridian, has loose wind heat, lung qi dispersing, determine effect of stem, control affection due to external wind and heat, cough silent, and measles is sent out smooth thoroughly, rubella pruritus etc.; Radix Saposhnikoviae, acrid-sweet flavor slightly warm in nature, enters liver spleen urinary bladder channel, has expelling pathogenic wind from the body surface, removing dampness to relieve pain, and cure mainly diseases caused by exogenous pathogenic factor table disease, the diseases such as rubella pruritus, for headache due to common cold, control wind and cold table disease, headache general pain, aversion to wind and cold person; Cortex Cinnamomi is dried bark and the branch skin of canella Cortex Cinnamomi, and acrid-sweet flavor heat, enters spleen kidney urinary bladder channel, have complement sun, warming the spleen and stomach, removing accumulated cold, effect of promoting blood circulation; Rhizoma Et Radix Notopterygii is the root and rhizome of samphire Rhizoma Et Radix Notopterygii, Radix et Rhizoma Notopterygii or angelica, the bitter temperature of acrid in the mouth, and enter urinary bladder channel kidney channel, have loose exterior cold, wind-damp dispelling, sharp joint, cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, and joint is ached; Herba Asari, acrid in the mouth is warm in nature, enters cardiopulmonary kidney channel, has expelling wind and cold, understand things pain-stopping, and effect of warming the lung for resolving phlegm, controls anemofrigid cold, and headache, has a toothache, nasal obstruction nasal sinusitis, and rheumatism numbness is led to, and phlegm retention such as to be breathed with cough the disease; Nidus Vespae is Vespidae insecticide hornet or the nest belonging to nearly source insecticide together, and sweet in the mouth is put down, and poisonous, enter liver lung meridian, have and dispel the wind, counteracting toxic substances, effect of parasite killing, controls infantile convulsion, migratory arthralgia, urticaria pruritus, tinea capitis etc.; Semen Sinapis Albae is the seed of crucifer Caulis et Folium Sinapis albee, and acrid in the mouth temperature, enters lung stomach warp, have promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain, control cough due to fluid-retention, fullness and distention in the chest and hypochondrium pain etc.; The Radix Angelicae Dahuricae is the dry root of umbellifer, and acrid in the mouth temperature, enters stomach lung large intestine channel, and have the dehumidifying of loose wind, understand things pain-stopping, detumescence and apocenosis, rash, induces sweat, for headache, and supraorbital bone pain, forehead is had a headache, toothache, nasal sinusitis, nasal obstruction, sinusitis, and cold-damp is suffered from abdominal pain, the diseases such as carbuncle pyogenic infections from tumour or sore; Flos Magnoliae, be the alabastrum of Magnoliacea plant Drymotaenium miyoshianum (Mak.) Mak., acrid in the mouth is warm in nature, enters lung stomach warp, has loose wind sensible, for nasal sinusitis nasal obstruction, the effects such as watery nasal discharge is stench; Spina Gleditsiae, be the Spina jujubae of leguminous plant Fructus Gleditsia, acrid in the mouth temperature, has and searches wind, draws out pus by applying a plaster to the affected part, detumescence, the diseases such as effect of evacuation of pus, controls carbuncle, sore, tinea skin ulcer; Rhizoma Acori Graminei is the rhizome of acorus gramineus araceae plant, acrid in the mouth, and tepor, enters conscience spleen channel, have and have one's ideas straightened out, eliminating phlegm, regulate the flow of vital energy, invigorate blood circulation, loose wind, and effect of dehumidifying, controls epilepsy, syncope due to accumulation of phlegm, and calentura coma is forgetful, and ambition is unhappy; Radix Scutellariae is the root of labiate Radix Scutellariae, bitter in the mouth, cold, enters cardiopulmonary gallbladder large intestine channel, has removing the relative excess fire, except damp and hot effect; Herba Schizonepetae, be the herb of labiate Herba Schizonepetae, acrid in the mouth temperature, enters lung Liver Channel, has and deliver, dispel the wind, effect for the treatment of blood disorders; Rhizoma Atractylodis are the rhizome of feverfew RHIZOMA ATRACTYLODIS IANCEAE or Atractylis chinensis etc., and the bitter temperature of acrid in the mouth, enters taste warp, have spleen invigorating, dampness, resolving depression, ward off dirty effect, control wet diseases such as being stranded spleen of containing; The Rhizoma Pinelliae, be the tuber of the aroid Rhizoma Pinelliae, acrid in the mouth temperature is poisonous, enters taste warp, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, and effect of dissolving lump and resolving mass controls damp-phlegm cold drink, the diseases such as syncope due to accumulation of phlegm headache; The Radix Astragali, be the root of the drying of leguminous plant Radix Astagali or Radix Astragali, sweet in the mouth temperature, enters lung spleen channel, the invigorating the spleen and replenishing QI of Radix Astragali (processed with Mel) energy, weak for the deficiency of vital energy, fatigue and weakness or sinking of QI of middle-JIAO, proctoptosis, the diseases such as edema; The Rhizoma Atractylodis Macrocephalae, bitter but sweet flavor temperature, enters taste warp, has invigorating the spleen and benefiting QI, effect of dampness diuretic; Poria is the dry sclerotia of Polyporaceae plant Poria, and slightly sweet flavor is put down, and have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, effect of mind tranquilizing and the heart calming, controls dysuria, edema distension, phlegm retention cough with dyspnea, the disease such as to have loose bowels.

The use usage of unguentum of the present invention and taboo: be coated with use outward, absorbent cotton is twisted into strip cotton balls, after revolving get 1/2 side ointment with cotton balls, fill in nostril, once a day, each treatment 1-2 hour, January is a course for the treatment of, general patient can cure a course for the treatment of, and severe patient is cured needs 2-3 the course for the treatment of; Avoid pungent, fish and shrimp, tobacco and wine, greasy irritable food etc.; Allergic constitution avoids use.(January is a course for the treatment of)

Detailed description of the invention

Embodiment

Clinical efficacy criterion and therapeutic outcome:

1, clinical data and Therapeutic Method:

The routine patients with rhinitis of 1.1 inventor in JIUYUE, 2008 to 2013 year JIUYUE 500, male 300 example, women 200 example, age 14-60 year, course of disease 1-15.

1.2 diagnostic criterias: with reference to dependent diagnostic standard formulation in " disease of tcm Standardization of diagnosis and curative effect " that " practical otorhinolaryngology " and State Administration of Traditional Chinese Medicine are promulgated:

1. symptom: nasal obstruction, snivel, sneeze, rhinocnesmus and nasal mucosa cardinal symptom and sign;

(2) sign: nasal cavity checks mucous hyperemia swelling;

(3) auxiliary examination: do x-ray inspection according to state of an illness some cases, gets rid of other pathological changes of nose.

1.3 curative effect judging standards: clinical cure: clinical symptoms, sign disappear, follow up a case by regular visits to six months without recurrence; Effective: nasal obstruction alleviates, nasal mucus reduces, rhinocnesmus alleviates; Invalid: clinical symptoms, sign has no significant change.

Therapeutic outcome: 500 routine patients with rhinitis, cures 350 examples, accounts for 70%, and responder accounts for 125 examples, and total effective rate accounts for 95%, and nonresponder accounts for 25 examples, accounts for 5%, and 350 routine healing persons had 300 example 1 course for the treatment of of treatment time, 50 routine healing time 2-3 course for the treatment of.(January is a course for the treatment of)

Model case 1: Liu xx, man, 16 years old, border on the river Shangqiu City Suiyang District shop village people in Henan Province, on March 20th, 2009 goes to a doctor, and suffers from allergic rhinitis for 2 years, repeatedly has a stuffy nose, flow clear nasal mucus, with headache, medicine Fructus Xanthii allergic rhinitis cream of the present invention is adopted to treat, after 1 course for the treatment of, symptom disappears substantially, follows up a case by regular visits to the state of an illness without recurrence after half a year.

Model case 2: horse xx, female, 18 years old, Shangqiu City Liangyuan District, Henan Province Shuan Ba people from town, June 5 2012 first visit time: diagnosis: patient has suffered from allergic rhinitis and had a surplus half a year, nasal obstruction, snivel, give Fructus Xanthii allergic rhinitis cream of the present invention treat 2 the course for the treatment of state of an illness return to one's perfect health, for consolidate curative effect, treat 1 course for the treatment of again, thoroughly cure, follow up a case by regular visits to the state of an illness after half a year without recurrence.

Model case 3: king x, man, 26 years old, Shangqiu City Ningling County, Henan Province Liuhe people from town, on June 15th, 2012 goes to a doctor, readme suffered from allergic rhinitis more than 1 year, and after treating 1 course for the treatment of with medicine Fructus Xanthii allergic rhinitis cream of the present invention, conscious nasal obstruction frequency reduces, flow clear nasal mucus to reduce, after 1 course for the treatment of of continual cure, fundamental symptoms disappears, and follows up a case by regular visits to the state of an illness without recurrence after half a year.

Model case 4 a: xx, man, 22 years old, Shangqiu City Zhecheng County of Henan Province Hu Xiang people from town, suffer from allergic rhinitis more than 2 years, on May 6th, 2010 goes to a doctor, often because increasing the weight of during contact cold air, time medical, disease sees nasal obstruction, sneeze, stream clear water nasal mucus, holding concurrently, it is cool to be afraid of, after treating 1 course for the treatment of with medicine Fructus Xanthii allergic rhinitis cream of the present invention, symptom is clearly better, continuation Drug therapy of the present invention was fully recovered after 1 course for the treatment of, followed up a case by regular visits to without recurrence after half a year.

Claims

1. Fructus Xanthii allergic rhinitis cream, is characterized in that it is made up of the raw material of following weight:

2. according to Fructus Xanthii allergic rhinitis cream according to claim 1, it is characterized in that its preparation method: by the drying respectively of above medicine, roguing, the process of preparing Chinese medicine, then smalls is ground into pulverizer, cross 120 mesh sieves for subsequent use, subsequently medicated powder is mixed homogeneously according to a conventional method paste making agent with appropriate lanoline, glycerol.