CN103720980A - Medicine for treating chronic nephritis - Google Patents
Medicine for treating chronic nephritis Download PDFInfo
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- CN103720980A CN103720980A CN201310675522.7A CN201310675522A CN103720980A CN 103720980 A CN103720980 A CN 103720980A CN 201310675522 A CN201310675522 A CN 201310675522A CN 103720980 A CN103720980 A CN 103720980A
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Abstract
The invention discloses a medicine for treating chronic nephritis, and belongs to the field of traditional Chinese medicines. The medicine is prepared from the following raw materials by weight: 20 g of astragalus membranaceus, 15 g of fructus kochiae, 15 g of angelica sinensis, 15 g of rhizoma atractylodis macrocephalae, 15 g of fructus lycii, 15 g of radix stephaniae tetrandrae, 15 g of pericarpium arecae, 15 g of monkshood, 15 g of ligusticum wallichii, 15 g of prepared rhizome of rehmannia, 15 g of eucommia ulmoides, 15 g of cornus officinalis, 15 g of the root of bidentate achyranthes, 10 g of cordyceps sinensis, 10 g of donkey-hide gelatin, 10 g of wolfiporia extensa, 10g of herba taxilli, 10 g of ephedra sinica stapf, 10 g of stiff silkworms, 10 g of cortex mori, 5 g of cortex cinnamomi, and 5 g of liquorice. The medicine for treating chronic nephritis has the effects of tonifying qi and yin, warming the kidney, inducing dieresis, replenishing qi to invigorate the spleen, and nourishing yin for suppressing hyperactive yang, is accurate in curative effect, produces an instant effect, and causes no toxic or side effects.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of chronic nephritis, belong to the field of Chinese medicines.
Background technology
Chronic nephritis is one group of chronic primary glomerulus diseases take hematuria, albuminuria, hypertension, edema as main clinical manifestation.Have onset slowly or concealment, protracted inflammation, the course of disease are longer, clinical albuminuria, hematuria, edema, the hypertension etc. of showing as of chronic nephritis more.This disease is to be caused by Different types of etiopathogenises, and doctor thinks mostly, and the cause of disease of chronic nephritis is a kind of with infection, particularly beta hemolytic streptococcus infects relevant immunoreactivity disease.
Nephritis treatment is mainly divided into western medical treatment and Chinese traditional treatment at present.Western medical treatment majority is to use hormone to treat, and this kind of therapy forcing up the targets simply, cure the symptoms, not the disease, and side effect is large.The traditional Chinese medical science adopts natural Chinese medicinal herb, is reached and is improved balance body constitution, thereby promote the function of body immunity by reparation damaged cell, reaches the effect for the treatment of both the principal and secondary aspects of a disease, evident in efficacy.
Summary of the invention
The object of this invention is to provide a kind of medicine for the treatment of chronic nephritis, this Chinese medicine composition can improve clinical symptoms, improves the adverse effect that primary disease brings patient.
The technical scheme that technical solution problem of the present invention is taked is: a kind of medicine for the treatment of chronic nephritis, it is characterized in that, and by the raw material of following weight, made: 20 grams of the Radixs Astragali, 15 grams of the Fructus Kochiae, 15 grams of Radix Angelicae Sinensis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of Fructus Lycii, 15 grams of Radixs Stephaniae Tetrandrae, 15 grams of Pericarpium Arecae, 15 grams of Radix Aconiti Lateralis Preparatas, 15 grams of Rhizoma Chuanxiongs, 15 grams, Radix Rehmanniae Preparata, 15 grams of the Cortexs Eucommiae, 15 grams of Fructus Corni, 15 grams of Radix Achyranthis Bidentataes, 10 grams of Cordyceps, 10 grams, Colla Corii Asini, 10 grams, Poria, 10 grams of Herba Taxillis, 10 grams, Herba Ephedrae, 10 grams of Bombyx Batryticatus, 10 grams of Cortex Mori, 5 grams of Cortex Cinnamomis, 5 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: raw material is mixed in marmite, adds water and soak in right amount; First intense fire is fried boiling, then with half an hour at a simmer, leaches medicinal liquid, adds water and decocts half an hour more in right amount, then leach medicinal liquid in medicinal residues.Twice medicinal liquid mixes, cools completely, and respectively at half an hour before breakfast, within after supper two hours, takes.Two weeks is a course for the treatment of.
Pharmacological action:
The Radix Astragali: warm in nature, sweet in the mouth.Tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.Cure mainly weakness of the spleen and stomach, lack of appetite asthenia, deficiency of vital energy blood prostration, exterior deficiency spontaneous perspiration, night sweat.
The Fructus Kochiae: sweetness and bitterness, cold.Enter kidney, urinary bladder channel.Diuresis, clearing away damp-heat.Control dysuria, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.
Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
The Rhizoma Atractylodis Macrocephalae: bitter sweet, temperature.Enter spleen, stomach warp.Spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive.Control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.
Fructus Lycii: sweet, flat.Enter liver, kidney channel.Nourishing kidney, lung moistening, tonifying liver, improving eyesight.Control hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, dizzy, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, seminal emission.
Radix Stephaniae Tetrandrae: hardship, cold.Return bladder, lung meridian.Inducing diuresis to remove edema, wind-expelling pain-stopping.For edema beriberi, dysuria, eczema sore, rheumatic arthralgia; Hypertension.
Pericarpium Arecae: therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, eliminating the pathogens from the lung in tune, easing stomach-QI, row water.Control gastral cavity abdomen painful abdominal mass swollen, logical intestine and small intestine, spleen benefiting and stimulating the appetite, dampness removing chases after wind, wide intestinal detumescence.
Radix Aconiti Lateralis Preparata: Xin Gan, heat, poisonous.Enter the heart, spleen, kidney channel.Recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispelling cold and removing dampness.Control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted contrary, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema children's intermittent infantile convulsion, anemofrigid-damp arthralgia, the contracture of Wei lame, sexual impotence, cold womb the moon, the disease of the leakage of cellulitis skin ulcer and all chronic diseaseses.
Rhizoma Chuanxiong: acrid in the mouth, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Rehmanniae Preparata: both kind YIN nourishing of enriching blood, again can vital essence replenishing and marrow benifiting, cure mainly the cloudy disease of losing oligospermia of all blood deficiency.Major function nourishing the blood and yin, vital essence replenishing and marrow benifiting, for blood deficiency and yellow complexion, dizzy, cardiopalmus.
The Cortex Eucommiae: enter liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is wanted to fall, frequent fetal movement, hypertension.
Fructus Corni: invigorating the liver and kidney, arresting seminal emission gas, Gu collapse.Control soreness of waist and knee joint, dizzy, tinnitus, sexual impotence, seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shakes scattered pulse.
Radix Achyranthis Bidentatae: raw dissipating blood stasis blood, the subduing inflammation used.Control gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury.
Cordyceps: tonifying deficiency, beneficial vital essence, relieving cough and resolving phlegm.Control phlegm retention and breathe heavily and cough, dyspnea due to deficiency, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, prolonged deficiency is multiple after being ill.
Colla Corii Asini: nourishing YIN and supplementing blood, antiabortive.Control blood deficiency, cough due to consumptive disease, spits blood, epistaxis, have blood in stool, and menoxenia, metrorrhagia, vaginal bleeding during pregnancy.
Poria: eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.
Herba Taxilli: invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood, antiabortive.Control soreness of waist and knee joint, a little less than muscles and bones flaccidity, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia.
Herba Ephedrae: arduous, temperature.Enter lung, urinary bladder channel.Diaphoresis, relievings asthma, diuretic.The cold table that cures the wound is real, and fever with chills is lossless, headache nasal obstruction, arthralgia, cough and asthma.
Bombyx Batryticatus: bring down a fever, cough-relieving, reduces phlegm, calm relieving convulsion, detumescence, and regulate nerve, participate in lipid metabolism.
Cortex Mori: eliminating pathogen from the lung for relieving asthma, line water detumescence.Control dyspnea and cough due to lung-heat, spit blood, edema, beriberi, dysuria.
Cortex Cinnamomi: complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion collapse, stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.
Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, grows and coughs lung moistening, emergency removing toxic substances, mediation hundred medicines.Cure mainly laryngopharynx swelling and pain, cellulitis skin infection, gastrointestinal ulceration and solution poison of drug, alimentary toxicosis etc.
The invention has the beneficial effects as follows: the present invention is by after said medicine combination, and its drug effect has synergism, and the medicine that this kind treated chronic nephritis has supplementing QI and nourishing YIN, warming the kidney to promote diuresis, replenishing QI to invigorate the spleen, the effect of nourishing YIN for suppressing the hyperactive YANG, and determined curative effect, instant effect, has no side effect.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical observation
1, clinical data: be selected from outpatient service and inpatient totally 80 examples in year March in April, 2012 to 2013, the age is 15-68 year, average 46.5 years old.
2, Therapeutic Method: take medicine of the present invention, decocting boils, takes at twice sooner or later.Two weeks is 1 course for the treatment of.
3, efficacy assessment standard:
Efficacy evaluation: one of 20 kinds of disease guideline of clinical investigations formulating for 1987 according to State Administration of Traditional Chinese Medicine (No. 0009) " guideline of clinical investigations for the treatment of chronic nephritis with Chinese medicine ".
(1) alleviate completely: the symptoms such as edema and sign disappear completely, urine protein examination continues negative, or twenty-four-hour urine protein quantification continues to be less than 0.2 gram, urine erythrocyte disappearance under high power lens.Urine sediments analyzer counting is normal, normal renal function.
(2) substantially alleviate: the symptoms such as edema and sign disappear substantially, and urine protein examination continuous decrease is more than 50%, and under high power lens, urine erythrocyte is no more than 3, Urine sediments analyzer counting approaches normal.Normal renal function or normal (only meeting 15% with normal value).
(3) take a turn for the better: the symptoms such as edema and sign are clearly better, one of urine protein examination continuous decrease+or twenty-four-hour urine protein quantification continuous decrease more than 25%, under high power lens, urine erythrocyte is no more than 5, normal renal function or be improved.
(4) invalid: clinical manifestation and above-mentioned real face chamber check and be all not improved or add severe one.
4, therapeutic outcome: alleviating 69 examples completely, is 86.25%; Partial rcsponse 7 examples are 8.75%; 3 examples that take a turn for the better are 3.75%; Invalid 1 example, is 1.25%, and total effective rate is 89%.The patient that wherein 69 examples are cured, follows up a case by regular visits to not recurrence in 1 year.
5, toxic and side effects analysis
In the 80 routine patients that observe, only have 2 examples to occur laxativeness after taking Chinese medicine of the present invention, the probability that occurs side reaction is only 2.5%, through disposing to the ill side reaction, disappears, and all the other are without any side effects.
In sum, the present invention is used for the treatment of the medicine of chronic nephritis, through clinical trial, shows that it can eliminate chronic nephritis symptom fast, effectively treats chronic nephritis, and effect is remarkable, and without obvious toxic-side effects.
Two, model case:
Case one, admires so-and-so, female, 46 years old.Patient's waist aches, weak more than 2 years, with intermittent microscopic hematuria, hypertension.Local hospital inspection is diagnosed as chronic nephritis.The Drug therapy such as oral inosine, VITAMIN C TABLET over 2 years, symptom is conscious to be alleviated, but outbreak repeatedly, and unexpected half a year before lumbago is weak increases the weight of, edema that two lower limb are slight.After taking two courses for the treatment of of Drug therapy of the present invention, Urinary inspection is turned out cloudy, and blood pressure is steady, and indices is replied normal, and just waist has also time and aches, continue to take medicine two courses for the treatment of, and lumbago transference cure.
Case two, lucky certain, man, 29 years old.Patient started edema of pair of lower extremities before 3 years, dizzy weak, through local hospital inspection, found urine protein, rear diagnosing chronic nephritis.Take prednisone, penicillin vein and the treatment such as splash into.After first quarter moon, edema disappears, but the albumen that has urine examined has no improvement, and after diseases caused by exogenous pathogenic factor or fatigue, edema is sent out whenever, time heavy when light, symptomatic recurrence recently, takes two courses for the treatment of of medicine that the present invention treats chronic nephritis, dizzy weak symptom alleviates, edema disappears.Continue to take medicine two courses for the treatment of, all symptoms disappear completely.Urine examination is normal, follows up a case by regular visits to and has no recurrence.
Case three, poplar, man, 16 years old.Before patient half a year, two lower limb slightly refer to pitting edema, and companion is dizzy, weak, be off one's feed, and hypourocrinia.At local hospital, look into: measuring blood pressure 180/120mmHg, serum creatinine 480umol/L, blood urea nitrogen 30.3mmol/L, be diagnosed as nephritis.Oral inosine, VITAMIN C TABLET, the Drug therapys such as prednisone, clinical symptom disappearance at that time, urine protein is turned out cloudy, afterwards symptomatic recurrence.Then adopt three courses for the treatment of of Drug therapy of the present invention, clinical symptom disappearance, all are normal in urine examination.Follow up a case by regular visits to 2 years, do not recur.
The specific embodiment
Embodiment 1:
Treat a medicine for chronic nephritis, by the raw material of following weight, made: 20 grams of the Radixs Astragali, 15 grams of the Fructus Kochiae, 15 grams of Radix Angelicae Sinensis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of Fructus Lycii, 15 grams of Radixs Stephaniae Tetrandrae, 15 grams of Pericarpium Arecae, 15 grams of Radix Aconiti Lateralis Preparatas, 15 grams of Rhizoma Chuanxiongs, 15 grams, Radix Rehmanniae Preparata, 15 grams of the Cortexs Eucommiae, 15 grams of Fructus Corni, 15 grams of Radix Achyranthis Bidentataes, 10 grams of Cordyceps, 10 grams, Colla Corii Asini, 10 grams, Poria, 10 grams of Herba Taxillis, 10 grams, Herba Ephedrae, 10 grams of Bombyx Batryticatus, 10 grams of Cortex Mori, 5 grams of Cortex Cinnamomis, 5 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: raw material is mixed in marmite, adds water and soak in right amount; First intense fire is fried boiling, then with half an hour at a simmer, leaches medicinal liquid, adds water and decocts half an hour more in right amount, then leach medicinal liquid in medicinal residues.Twice medicinal liquid mixes, cools completely, and respectively at half an hour before breakfast, within after supper two hours, takes.Two weeks is a course for the treatment of.
Claims (1)
1. a medicine for the treatment of chronic nephritis, is characterized in that, by the raw material of following weight, is made: 20 grams of the Radixs Astragali, 15 grams of the Fructus Kochiae, 15 grams of Radix Angelicae Sinensis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of Fructus Lycii, 15 grams of Radixs Stephaniae Tetrandrae, 15 grams of Pericarpium Arecae, 15 grams of Radix Aconiti Lateralis Preparatas, 15 grams of Rhizoma Chuanxiongs, 15 grams, Radix Rehmanniae Preparata, 15 grams of the Cortexs Eucommiae, 15 grams of Fructus Corni, 15 grams of Radix Achyranthis Bidentataes, 10 grams of Cordyceps, 10 grams, Colla Corii Asini, 10 grams, Poria, 10 grams of Herba Taxillis, 10 grams, Herba Ephedrae, 10 grams of Bombyx Batryticatus, 10 grams of Cortex Mori, 5 grams of Cortex Cinnamomis, 5 grams, Radix Glycyrrhizae.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104027625A (en) * | 2014-05-15 | 2014-09-10 | 赵玲 | Traditional Chinese medicine composition for treating chronic nephritis |
| CN104398988A (en) * | 2014-11-29 | 2015-03-11 | 高春娟 | Medicament for treating chronic nephritis and preparation method thereof |
| CN104645144A (en) * | 2015-03-23 | 2015-05-27 | 王雪雁 | Traditional Chinese medicine preparation for treating nephritis and preparation method of traditional Chinese medicine preparation |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101204481A (en) * | 2007-12-17 | 2008-06-25 | 牟培超 | Chinese traditional medicine for chronic nephritis |
| CN101496864A (en) * | 2008-01-28 | 2009-08-05 | 天科仁祥技术（北京）有限责任公司 | Chinese medicament preparation for treating renal proteinuria and diabetic renal proteinuria and preparation method thereof |
| CN101700340A (en) * | 2009-11-16 | 2010-05-05 | 张晨 | Oral traditional Chinese medicine composition for treating chronic nephritis |
-
2013
- 2013-12-12 CN CN201310675522.7A patent/CN103720980A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101204481A (en) * | 2007-12-17 | 2008-06-25 | 牟培超 | Chinese traditional medicine for chronic nephritis |
| CN101496864A (en) * | 2008-01-28 | 2009-08-05 | 天科仁祥技术（北京）有限责任公司 | Chinese medicament preparation for treating renal proteinuria and diabetic renal proteinuria and preparation method thereof |
| CN101700340A (en) * | 2009-11-16 | 2010-05-05 | 张晨 | Oral traditional Chinese medicine composition for treating chronic nephritis |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104027625A (en) * | 2014-05-15 | 2014-09-10 | 赵玲 | Traditional Chinese medicine composition for treating chronic nephritis |
| CN104398988A (en) * | 2014-11-29 | 2015-03-11 | 高春娟 | Medicament for treating chronic nephritis and preparation method thereof |
| CN104645144A (en) * | 2015-03-23 | 2015-05-27 | 王雪雁 | Traditional Chinese medicine preparation for treating nephritis and preparation method of traditional Chinese medicine preparation |
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Application publication date: 20140416 |