CN104968664A - 作为酪氨酸激酶抑制剂的并环化合物 - Google Patents

作为酪氨酸激酶抑制剂的并环化合物 Download PDF

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CN104968664A
CN104968664A CN201380072466.6A CN201380072466A CN104968664A CN 104968664 A CN104968664 A CN 104968664A CN 201380072466 A CN201380072466 A CN 201380072466A CN 104968664 A CN104968664 A CN 104968664A
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alkyl
amino
yue
hydrogen atom
phenyl
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张倩
张艳
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KBP Biosciences Co Ltd
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KBP Biosciences Co Ltd
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Abstract

本发明涉及通式(I)所示的化合物，制备所述化合物的方法，含有所述化合物的药物组合物，以及所述化合物在制备用于预防和/或治疗B细胞相关的血癌、炎性以及自身免疫性疾病的药物中的应用，其中X、W、环A、环B、L1、L2、R1、R2、R3、

Description

PCT国内申请，说明书已公开。

Claims (1)

  1. PCT国内申请，权利要求书已公开。
CN201380072466.6A 2012-12-12 2013-12-12 作为酪氨酸激酶抑制剂的并环化合物 Pending CN104968664A (zh)

Priority Applications (1)

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CN201380072466.6A CN104968664A (zh) 2012-12-12 2013-12-12 作为酪氨酸激酶抑制剂的并环化合物

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CN201210534945 2012-12-12
CN201210534945.2 2012-12-12
CN201380072466.6A CN104968664A (zh) 2012-12-12 2013-12-12 作为酪氨酸激酶抑制剂的并环化合物
PCT/CN2013/001555 WO2014089913A1 (zh) 2012-12-12 2013-12-12 作为酪氨酸激酶抑制剂的并环化合物

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CN104968664A true CN104968664A (zh) 2015-10-07

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WO (1) WO2014089913A1 (zh)

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US9388185B2 (en) 2012-08-10 2016-07-12 Incyte Holdings Corporation Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
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US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
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JP7402804B2 (ja) 2018-02-01 2023-12-21 マイオカーディア，インク ピラゾール化合物及びその調製
KR20210018265A (ko) 2018-05-04 2021-02-17 인사이트 코포레이션 Fgfr 억제제의 고체 형태 및 이의 제조 방법
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US11066404B2 (en) * 2018-10-11 2021-07-20 Incyte Corporation Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
US11384083B2 (en) 2019-02-15 2022-07-12 Incyte Corporation Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
WO2020180959A1 (en) 2019-03-05 2020-09-10 Incyte Corporation Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors
US11628162B2 (en) 2019-03-08 2023-04-18 Incyte Corporation Methods of treating cancer with an FGFR inhibitor
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US11591329B2 (en) 2019-07-09 2023-02-28 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
EP4013750A1 (en) 2019-08-14 2022-06-22 Incyte Corporation Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors
US20230027026A1 (en) * 2019-09-27 2023-01-26 Jubilant Biosys Limited Fused pyrimidine compounds, compositions and medicinal applications thereof
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WO2021076728A1 (en) 2019-10-16 2021-04-22 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
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