CN104873593B - A kind of pharmaceutical composition and preparation method thereof of prevention milk cow retention of afterbirth - Google Patents
A kind of pharmaceutical composition and preparation method thereof of prevention milk cow retention of afterbirth Download PDFInfo
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- CN104873593B CN104873593B CN201510350213.1A CN201510350213A CN104873593B CN 104873593 B CN104873593 B CN 104873593B CN 201510350213 A CN201510350213 A CN 201510350213A CN 104873593 B CN104873593 B CN 104873593B
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Abstract
The invention discloses a kind of pharmaceutical compositions and preparation method thereof of prevention milk cow retention of afterbirth, belong to field of veterinary.The pharmaceutical composition is made of the root of bidentate achyranthes, chingma abutilon seed, motherwort, Chinese cassia tree, Radix Astragali, plantain seed, sesame oil, safflower, Caulis Spatholobi, dianthus superbus, akebi, Radix Angelicae Sinensis, Radix Codonopsis, Radix Glycyrrhizae, peach kernel, Rhizoma Chuanxiong, red halloysite, calcium lactate.Preparation method is to clean medicinal material respectively, weigh, and is ground into coarse powder, the water extraction of 14 times of amounts of addition, and concentration obtains extract after dry, and red halloysite, calcium lactate stir evenly.The present invention has the contractility for increasing cow uteri, promotes afterbirth discharge, reduces lochia efflux time, improves reproductive performance.
Description
Technical field
The invention belongs to field of veterinary, and in particular to it is a kind of prevention milk cow retention of afterbirth pharmaceutical composition and its preparation side
Method, the present invention can effectively improve the reproductive performance of milk cow for preventing and treating milk cow retention of afterbirth symptom.
Background technology
Milk cow retention of afterbirth is called the stagnation of milk cow afterbirth.After referring to cow output tire calf, within a certain period of time, afterbirth cannot take off
It falls and is stranded in intrauterine.The retention of afterbirth of milk cow is divided into two kinds of situations, wherein relatively common is whole retention of afterbirth cases
(exposing of some afterbirth is hung over outside vaginal orifice), such case is easier to make diagnosis；The second situation is part afterbirth
Under not, because this undischarged a part of afterbirth remains in intrauterine.The milk cow of retention of afterbirth will appear the extension of lochia efflux time,
The afterbirth fragment of corruption is included, hogback exerts duty again and again, and systemic toxicity profiles phenomenon, body temperature raising, appetite occurs in spoilage product after absorbing
Reduction or endometrium inflammation etc. are ruminated in depressed, stomach and intestine hypofunction.
The cause of disease of milk cow retention of afterbirth：
One, postpartum uterine inertia
1, single or very poor quality feedstuff, daily ration mineral, hypovitaminosis and deficiency is used for a long time；
2, dry breast phase amount of exercise is insufficient, and light application time is short；
3, dairy cow nutrition is bad, become thin or excessively feed fine fodder make body overfertilization etc. and can cause postpartum uterine contractile without
Power.
Two, by the afterbirth adhesion caused by inflammation of uterus：Such as mycotic infection, Virus entry, endometritis, are drawn
It plays placenta and endometrium inflammation then causes soft tissue hyperplasia that fetal placenta and placenta materna is caused to stick together.
At present antibiotic, but the side effect that antibiotic is brought mainly are used about the control method of milk cow retention of afterbirth
Thereupon, antibiotic largely remains, and there are the off-drug periods, are had brought tremendous economic losses to aquaculture.Medicine group of the present invention
Closing object has it natural, and safety, no drug residue, no medicine phase can effectively prevent and treat milk cow retention of afterbirth symptom.
Invention content
The object of the present invention is to provide it is a kind of it is natural, efficiently, the pharmaceutical composition of the prevention milk cow retention of afterbirth of no drug residue,
To improve the production performance of milk cow.
The invention is realized in this way：
It is a kind of prevention milk cow retention of afterbirth pharmaceutical composition be prepared by following raw material in parts by weight：Root of bidentate achyranthes 5-15
It is part, 1-10 parts of chingma abutilon seed, 5-15 parts of motherwort, 1-10 parts of Chinese cassia tree, 1-10 parts of Radix Astragali, 5-15 parts of plantain seed, 1-5 parts of sesame oil, red
1-5 parts of flower, 1-10 parts of Caulis Spatholobi, 1-10 parts of dianthus superbus, 1-5 parts of akebi, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of Radix Codonopsis, 1-5 parts of Radix Glycyrrhizae, peach
1-10 parts of benevolence, 1-10 parts of Rhizoma Chuanxiong, 1-10 parts of red halloysite, 1-10 parts of calcium lactate.
The present invention is realized by following technical method：
It is a kind of prevention milk cow retention of afterbirth pharmaceutical composition be prepared by following raw material in parts by weight：Root of bidentate achyranthes 8-12
Part, 2-8 parts of chingma abutilon seed, 8-12 parts of motherwort, 2-8 parts of Chinese cassia tree, 2-8 parts of Radix Astragali, 8-12 parts of plantain seed, 1-4 parts of sesame oil, safflower 1-
4 parts, 2-8 parts of Caulis Spatholobi, 2-8 parts of dianthus superbus, 1-4 parts of akebi, 2-8 parts of Radix Angelicae Sinensis, 2-8 parts of Radix Codonopsis, 1-4 parts of Radix Glycyrrhizae, 2-8 parts of peach kernel,
2-8 parts of Rhizoma Chuanxiong, 2-8 parts of red halloysite, 2-8 parts of calcium lactate.
The present invention is realized by following technical method：
It is a kind of prevention milk cow retention of afterbirth pharmaceutical composition be prepared by following raw material in parts by weight：The root of bidentate achyranthes 10
Part, 5 parts of chingma abutilon seed, 10 parts of motherwort, 5 parts of Chinese cassia tree, 5 parts of Radix Astragali, 10 parts of plantain seed, 3 parts of sesame oil, 3 parts of safflower, 5 parts of Caulis Spatholobi,
5 parts of dianthus superbus, 2 parts of akebi, 5 parts of Radix Angelicae Sinensis, 6 parts of Radix Codonopsis, 2 parts of Radix Glycyrrhizae, 5 parts of peach kernel, 4 parts of Rhizoma Chuanxiong, 5 parts of red halloysite, 5 parts of calcium lactate.
It is a kind of prevention milk cow retention of afterbirth pharmaceutical composition be prepared by following methods：
(1) by the root of bidentate achyranthes, chingma abutilon seed, motherwort, Chinese cassia tree, Radix Astragali, plantain seed, sesame oil, safflower, Caulis Spatholobi, dianthus superbus, akebi,
Radix Angelicae Sinensis, Radix Codonopsis, Radix Glycyrrhizae, peach kernel, Ligusticum chuanxiong Hort are cleaned, dry, weigh, and pulverizing medicinal materials are at coarse powder；
(2) medicinal material coarse powder is added to 1-5 times of water, is heated to boiling, is allowed to the 1-4h that boils, every time extraction 1-4 times, reflux
To medicinal extract, vacuum drying obtains extract at powder；
(3) red halloysite, calcium lactate are mixed with the above extract in appropriate proportions, stirs 10-20min.
A kind of pharmaceutical composition of prevention milk cow retention of afterbirth is it is characterized in that its auxiliary material addition silica, dextrin, sugarcane
Sugar etc. is one such or two or more.
Beneficial effects of the present invention are as follows：
1, the present invention is combined with traditional tcm theory with present production technology, makes the active ingredient of product most
That changes greatly extracts.
2, the present invention can not only prevent milk cow retention of afterbirth, and the effect of benefiting qi and nourishing blood.
3, no drug residue of the present invention can ensure food security.
Specific implementation mode
It elaborates to the present invention below by embodiment, does not therefore limit the present invention to the embodiment described model
Among enclosing.
Embodiment 1
5 parts of the root of bidentate achyranthes, 1 part of chingma abutilon seed, 5 parts of motherwort, 1 part of Chinese cassia tree, 1 part of Radix Astragali, 5 parts of plantain seed, 1 part of sesame oil, safflower 1
Part, 1 part of Caulis Spatholobi, 1 part of dianthus superbus, 1 part of akebi, 1 part of Radix Angelicae Sinensis, 1 part of Radix Codonopsis, 1 part of Radix Glycyrrhizae, 1 part of peach kernel, 1 part of Rhizoma Chuanxiong, red halloysite 1
Part, 1 part of calcium lactate.
Preparation method is as follows：
(1) by the root of bidentate achyranthes, chingma abutilon seed, motherwort, Chinese cassia tree, Radix Astragali, plantain seed, sesame oil, safflower, Caulis Spatholobi, dianthus superbus, akebi,
Radix Angelicae Sinensis, Radix Codonopsis, Radix Glycyrrhizae, peach kernel, Ligusticum chuanxiong Hort are cleaned, dry, weigh, and pulverizing medicinal materials are at coarse powder；
(2) medicinal material coarse powder is added to 1 times of water, is heated to boiling, is allowed to the 1h that boils, extraction 1 time, is back to leaching every time
Cream, vacuum drying obtain extract at powder；
(3) red halloysite, calcium lactate are mixed with the above extract in appropriate proportions, stirs 10min, the auxiliary materials such as sucrose are added
Product is made.
Embodiment 2
10 parts of the root of bidentate achyranthes, 5 parts of chingma abutilon seed, 10 parts of motherwort, 5 parts of Chinese cassia tree, 5 parts of Radix Astragali, 10 parts of plantain seed, 2 parts of sesame oil, safflower
3 parts, 5 parts of Caulis Spatholobi, 5 parts of dianthus superbus, 3 parts of akebi, 5 parts of Radix Angelicae Sinensis, 5 parts of Radix Codonopsis, 2 parts of Radix Glycyrrhizae, 5 parts of peach kernel, 5 parts of Rhizoma Chuanxiong, red halloysite 5
Part, 5 parts of calcium lactate.
Preparation method is as follows：
(1) by the root of bidentate achyranthes, chingma abutilon seed, motherwort, Chinese cassia tree, Radix Astragali, plantain seed, sesame oil, safflower, Caulis Spatholobi, dianthus superbus, akebi,
Radix Angelicae Sinensis, Radix Codonopsis, Radix Glycyrrhizae, peach kernel, Ligusticum chuanxiong Hort are cleaned, dry, weigh, and pulverizing medicinal materials are at coarse powder；
(2) medicinal material coarse powder is added to 3 times of water, is heated to boiling, is allowed to the 3h that boils, extraction 3 times, are back to leaching every time
Cream, vacuum drying obtain extract at powder；
(3) red halloysite, calcium lactate are mixed with the above extract in appropriate proportions, stirs 15min, the auxiliary materials such as sucrose are added
Product is made.
Embodiment 3
15 parts of the root of bidentate achyranthes, 10 parts of chingma abutilon seed, 15 parts of motherwort, 10 parts of Chinese cassia tree, 10 parts of Radix Astragali, 15 parts of plantain seed, 5 parts of sesame oil,
5 parts of safflower, 10 parts of Caulis Spatholobi, 10 parts of dianthus superbus, 5 parts of akebi, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Codonopsis, 5 parts of Radix Glycyrrhizae, 10 parts of peach kernel, Rhizoma Chuanxiong 10
Part, 10 parts of red halloysite, 10 parts of calcium lactate.
Preparation method is as follows：
(1) by the root of bidentate achyranthes, chingma abutilon seed, motherwort, Chinese cassia tree, Radix Astragali, plantain seed, sesame oil, safflower, Caulis Spatholobi, dianthus superbus, akebi,
Radix Angelicae Sinensis, Radix Codonopsis, Radix Glycyrrhizae, peach kernel, Ligusticum chuanxiong Hort are cleaned, dry, weigh, and pulverizing medicinal materials are at coarse powder；
(2) medicinal material coarse powder is added to 5 times of water, is heated to boiling, is allowed to the 4h that boils, extraction 4 times, are back to leaching every time
Cream, vacuum drying obtain extract at powder；
(3) red halloysite, calcium lactate are mixed with the above extract in appropriate proportions, stirs 20min, the auxiliary materials such as sucrose are added
Product is made.
Test example
The prophylactic tria of milk cow retention of afterbirth
Selection also has five days just before giving birth milk cows 50, is divided into 2 groups, every group each 25, one group of feeding contains medicine of the present invention
The feed of object, another group is control group fed chow diet, is fed five days.Afterbirth situation after observation milk cow calving.
The pharmaceutical composition prevention group of 1 present invention of table is with control group to the prevention situation of milk cow retention of afterbirth
Test result：By testing it is found that the case of control group milk cow retention of afterbirth reaches 32%, milk cow afterbirth of the present invention is not
Lower case is 0, and compared with the control group, drug of the present invention can effectively prevent the generation of milk cow retention of afterbirth case.
The therapeutic test of milk cow retention of afterbirth
The milk cow case 50 for selecting milk cow retention of afterbirth is divided into 2 groups, and every group each 25, the drug of medicine group is used
It is gavaged after suitable water dilution, blank group is not added with any drug.Observe milk cow afterbirth incidence.
The medicine composite for curing group of 2 present invention of table is with control group to the treatment of milk cow retention of afterbirth
Test result：By experiment it is found that the case of control group milk cow retention of afterbirth reaches 100%, milk cow afterbirth of the present invention
It is 0 not descend case, and compared with the control group, drug of the present invention can effectively treat the generation of milk cow retention of afterbirth case.
Claims (5)
1. a kind of pharmaceutical composition of prevention milk cow retention of afterbirth, is prepared by following raw material in parts by weight：Root of bidentate achyranthes 5-15
It is part, 1-10 parts of chingma abutilon seed, 5-15 parts of motherwort, 1-10 parts of Chinese cassia tree, 1-10 parts of Radix Astragali, 5-15 parts of plantain seed, 1-5 parts of sesame oil, red
1-5 parts of flower, 1-10 parts of Caulis Spatholobi, 1-10 parts of dianthus superbus, 1-5 parts of akebi, 1-10 parts of Radix Angelicae Sinensis, 1-10 parts of Radix Codonopsis, 1-5 parts of Radix Glycyrrhizae, peach
1-10 parts of benevolence, 1-10 parts of Rhizoma Chuanxiong, 1-10 parts of red halloysite, 1-10 parts of calcium lactate.
2. a kind of pharmaceutical composition of prevention milk cow retention of afterbirth according to claim 1 is by the raw material of following parts by weight
It is prepared：8-12 parts of the root of bidentate achyranthes, 2-8 parts of chingma abutilon seed, 8-12 parts of motherwort, 2-8 parts of Chinese cassia tree, 2-8 parts of Radix Astragali, plantain seed 8-12
It is part, 1-4 parts of sesame oil, 1-4 parts of safflower, 2-8 parts of Caulis Spatholobi, 2-8 parts of dianthus superbus, 1-4 parts of akebi, 2-8 parts of Radix Angelicae Sinensis, 2-8 parts of Radix Codonopsis, sweet
1-4 parts careless, 2-8 parts of peach kernel, 2-8 parts of Rhizoma Chuanxiong, 2-8 parts of red halloysite, 2-8 parts of calcium lactate.
3. a kind of pharmaceutical composition of prevention milk cow retention of afterbirth according to claim 2 is by the raw material of following parts by weight
It is prepared：It is 10 parts of the root of bidentate achyranthes, 5 parts of chingma abutilon seed, 10 parts of motherwort, 5 parts of Chinese cassia tree, 5 parts of Radix Astragali, 10 parts of plantain seed, 3 parts of sesame oil, red
Spend 3 parts, 5 parts of Caulis Spatholobi, 5 parts of dianthus superbus, 2 parts of akebi, 5 parts of Radix Angelicae Sinensis, 6 parts of Radix Codonopsis, 2 parts of Radix Glycyrrhizae, 5 parts of peach kernel, 4 parts of Rhizoma Chuanxiong, red stone
5 parts of fat, 5 parts of calcium lactate.
4. a kind of pharmaceutical composition of prevention milk cow retention of afterbirth according to claim 1 prepared by following preparation method and
At：
(1) by the root of bidentate achyranthes, chingma abutilon seed, motherwort, Chinese cassia tree, Radix Astragali, plantain seed, sesame oil, safflower, Caulis Spatholobi, dianthus superbus, akebi, Radix Angelicae Sinensis,
Radix Codonopsis, Radix Glycyrrhizae, peach kernel, Ligusticum chuanxiong Hort are cleaned, dry, weigh, and pulverizing medicinal materials are at coarse powder；
(2) medicinal material coarse powder is added to 1-5 times of water, is heated to boiling, is allowed to the 1-4h that boils, extraction 1-4 times, is back to leaching every time
Cream, vacuum drying obtain extract at powder；
(3) red halloysite, calcium lactate are mixed with the above extract in appropriate proportions, stirs 10-20min.
5. a kind of pharmaceutical composition of prevention milk cow retention of afterbirth according to claim 4 is it is characterized in that add auxiliary
Material.
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| CN201510350213.1A CN104873593B (en) | 2015-06-24 | 2015-06-24 | A kind of pharmaceutical composition and preparation method thereof of prevention milk cow retention of afterbirth |
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| CN106389977A (en) * | 2016-11-17 | 2017-02-15 | 中悦民安（北京）科技发展有限公司 | Traditional Chinese composite preparation for treating retained fetal membranes of dairy cow and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101972331A (en) * | 2010-10-20 | 2011-02-16 | 罗志诣 | Chinese medicinal composition for treating cow afterbirth retention |
| CN104173660A (en) * | 2014-09-04 | 2014-12-03 | 青岛农业大学 | Composition for treating retained placenta in cattle and preparation method of composition |
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2015
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101972331A (en) * | 2010-10-20 | 2011-02-16 | 罗志诣 | Chinese medicinal composition for treating cow afterbirth retention |
| CN104173660A (en) * | 2014-09-04 | 2014-12-03 | 青岛农业大学 | Composition for treating retained placenta in cattle and preparation method of composition |
Non-Patent Citations (1)
| Title |
|---|
| 浅谈奶牛胎衣不下的中西医防治;刘志英等;《北方牧业》;20081231(第16期);18 * |
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