CN104644557B - 卟啉铁固体分散体及其制备方法 - Google Patents
卟啉铁固体分散体及其制备方法 Download PDFInfo
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- CN104644557B CN104644557B CN201310596082.6A CN201310596082A CN104644557B CN 104644557 B CN104644557 B CN 104644557B CN 201310596082 A CN201310596082 A CN 201310596082A CN 104644557 B CN104644557 B CN 104644557B
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- solid dispersions
- porphyrin iron
- porphyrin
- cellulose
- iron
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
配方名称 | 配方1-1 | 配方1-2 | 配方1-3 | 配方1-4 |
标示量(%) | 93.3 | 95.7 | 97.1 | 96.5 |
配方名称 | 配方2-1 | 配方2-2 | 配方2-3 |
标示量(%) | 94.7 | 92.0 | 93.5 |
配方名称 | 配方3-1 | 配方3-2 | 配方3-3 |
标示量(%) | 95.6 | 85.5 | 91.7 |
Claims (21)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310596082.6A CN104644557B (zh) | 2013-11-22 | 2013-11-22 | 卟啉铁固体分散体及其制备方法 |
US15/033,310 US10391103B2 (en) | 2013-11-22 | 2014-11-17 | Ferroporphyrin solid dispersion and preparation method thereof |
PCT/CN2014/091260 WO2015074524A1 (zh) | 2013-11-22 | 2014-11-17 | 卟啉铁固体分散体及其制备方法 |
KR1020167016749A KR101800855B1 (ko) | 2013-11-22 | 2014-11-17 | 페로포르피린 고체 분산체 및 그의 제조 방법 |
JP2016554783A JP6181322B2 (ja) | 2013-11-22 | 2014-11-17 | フェロポルフィリン固体分散体およびその製造方法 |
HK15111411.1A HK1210695A1 (zh) | 2013-11-22 | 2015-11-19 | 卟啉鐵固體分散體及其製備方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310596082.6A CN104644557B (zh) | 2013-11-22 | 2013-11-22 | 卟啉铁固体分散体及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104644557A CN104644557A (zh) | 2015-05-27 |
CN104644557B true CN104644557B (zh) | 2017-10-31 |
Family
ID=53178931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310596082.6A Active CN104644557B (zh) | 2013-11-22 | 2013-11-22 | 卟啉铁固体分散体及其制备方法 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10391103B2 (zh) |
JP (1) | JP6181322B2 (zh) |
KR (1) | KR101800855B1 (zh) |
CN (1) | CN104644557B (zh) |
HK (1) | HK1210695A1 (zh) |
WO (1) | WO2015074524A1 (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108785256B (zh) * | 2017-04-28 | 2021-06-29 | 江苏恒瑞医药股份有限公司 | 一种固体分散体及其制备方法 |
CN109053744A (zh) * | 2017-10-24 | 2018-12-21 | 陈志龙 | 新型卟吩双醚盐类化合物及其制备方法与应用 |
CN108186407B (zh) * | 2018-02-24 | 2019-09-20 | 珀莱雅化妆品股份有限公司 | 一种具有美白抗老功效的固体分散体的制备方法 |
KR102084489B1 (ko) * | 2018-05-18 | 2020-03-04 | 강원대학교산학협력단 | 열용융압출법을 이용하여 제조된 철 나노콜로이드 분산체 및 이의 용도 |
KR102104257B1 (ko) * | 2018-05-18 | 2020-04-24 | 강원대학교산학협력단 | 열용융압출법을 이용하여 제조된 망간 나노콜로이드 분산체 및 이의 용도 |
CN110026238A (zh) * | 2019-05-24 | 2019-07-19 | 中国石油大学(华东) | 一种纳米棒状光催化材料及制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1090759A (zh) * | 1993-02-09 | 1994-08-17 | 上海市农业科学院 | 血红素药物 |
WO2007079139A9 (en) * | 2005-12-28 | 2007-11-29 | Vertex Pharma | Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
CN102793706A (zh) * | 2012-08-14 | 2012-11-28 | 浙江华海药业股份有限公司 | 托伐普坦固体分散体的制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0639366B2 (ja) * | 1989-05-22 | 1994-05-25 | 資忠 松島 | 埴物成長促進剤 |
DE19709663A1 (de) * | 1997-03-10 | 1998-09-17 | Basf Ag | Verwendung von redispergierbaren Polymerpulvern oder Polymergranulaten als Bindemittel zur Herstellung von festen pharmazeutischen Darreichungsformen |
JP5159012B2 (ja) * | 1999-12-23 | 2013-03-06 | メイン・ファ−マ・インタ−ナショナル・プロプライエタリ−・リミテッド | 不良溶解性の薬物に対する改良された医薬組成物 |
JPWO2004108164A1 (ja) * | 2003-06-04 | 2006-07-20 | 協和醗酵工業株式会社 | コーティング用組成物およびコーティング製剤 |
US20060134227A1 (en) * | 2004-12-22 | 2006-06-22 | Bortz Jonathan D | Compositions including iron |
WO2006087919A1 (ja) * | 2005-01-28 | 2006-08-24 | Takeda Pharmaceutical Company Limited | 難水溶性物質含有微細化組成物 |
US7585527B2 (en) * | 2005-09-19 | 2009-09-08 | Bala Venkataraman | Composition and method for treating iron deficiency anemia |
CN101254207A (zh) * | 2008-02-29 | 2008-09-03 | 河北师范大学 | 补铁剂脂质体铁及其制备方法 |
EP2341084B1 (en) * | 2009-12-30 | 2015-02-25 | Dow Global Technologies LLC | Redispersible polymer powders stabilized with protective colloid compositions |
CA2857153A1 (en) * | 2011-12-01 | 2013-06-06 | Infacare Pharmaceutical Corporation | Methods for treating hyperbilirubinemia with stannsoporfin |
WO2013150000A1 (en) * | 2012-04-03 | 2013-10-10 | Basf Se | Compositions comprising granules of phthalocyanines |
-
2013
- 2013-11-22 CN CN201310596082.6A patent/CN104644557B/zh active Active
-
2014
- 2014-11-17 KR KR1020167016749A patent/KR101800855B1/ko active IP Right Grant
- 2014-11-17 JP JP2016554783A patent/JP6181322B2/ja active Active
- 2014-11-17 WO PCT/CN2014/091260 patent/WO2015074524A1/zh active Application Filing
- 2014-11-17 US US15/033,310 patent/US10391103B2/en active Active
-
2015
- 2015-11-19 HK HK15111411.1A patent/HK1210695A1/zh unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1090759A (zh) * | 1993-02-09 | 1994-08-17 | 上海市农业科学院 | 血红素药物 |
WO2007079139A9 (en) * | 2005-12-28 | 2007-11-29 | Vertex Pharma | Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
CN102793706A (zh) * | 2012-08-14 | 2012-11-28 | 浙江华海药业股份有限公司 | 托伐普坦固体分散体的制备方法 |
Non-Patent Citations (1)
Title |
---|
正交试验优选氯化血红素缓释固体分散体处方;第1期;《中国医院药学杂志》;20080131;第28卷(第1期);第9-11页,尤其是摘要,第9页左栏第1段,右栏第2段 * |
Also Published As
Publication number | Publication date |
---|---|
US10391103B2 (en) | 2019-08-27 |
KR101800855B1 (ko) | 2017-11-23 |
KR20160089468A (ko) | 2016-07-27 |
HK1210695A1 (zh) | 2016-05-06 |
CN104644557A (zh) | 2015-05-27 |
US20160243130A1 (en) | 2016-08-25 |
WO2015074524A1 (zh) | 2015-05-28 |
JP2016537429A (ja) | 2016-12-01 |
JP6181322B2 (ja) | 2017-08-16 |
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Inventor after: Wan Jiansheng Inventor after: Li Kun Inventor after: Gu Maojian Inventor before: Fang Yun Inventor before: Wan Jiansheng Inventor before: Li Kun Inventor before: Gu Maojian |
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CP03 | Change of name, title or address | ||
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Address after: Room 205, 207, 515 huanke Road, China (Shanghai) pilot Free Trade Zone, Pudong New Area, Shanghai, 201210 Patentee after: Shanghai xuantai Pharmaceutical Technology Co., Ltd Address before: 201203 Shanghai City, Pudong New Area Zhangjiang Road No. 99, No. 3, Haike Building 1 floor Patentee before: SINOTHERAPEUTICS Inc. |