CN104547527A - Traditional Chinese medicine composition for treating sphagitis - Google Patents
Traditional Chinese medicine composition for treating sphagitis Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses a traditional Chinese medicine composition for treating sphagitis. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 5-10 parts of rehmannia root, 5-15 parts of trollflower, 5-12 parts of figwort root, 5-12 parts of dwarf lilyturf root, 5-12 parts of vietnamese sophora root, 5-10 parts of honeysuckle, 5-15 parts of blackberry lily, 3-10 parts of Indian trumpet flower, 3-10 parts of arrowshaped tinospora root, 3-10 parts of platycodon root, 5-15 parts of boat-fruited sterculia seed, 3-10 parts of cicada slough and 2-8 parts of raw liquorice root. The traditional Chinese medicine composition is capable of effectively killing various bacteria causing the inflammations of the throat and avoiding the stay of the bacteria and bacterial secretion to eliminate the inflammations of the throat due to a remarkable synergic effect between the components.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition that can be used as treatment pharyngolaryngitis medicine.
Background technology
Pharyngolaryngitis is bottleneck throat mucosa, submucous tissue and adenoid active chronic inflammation; generally caused by antibacterial or virus; there is the course of disease long, easily repeatedly, be difficult to the feature of curing; the clinical common sympton of this disease comprises larynx sense discomfort; foreign body sensation, burn feeling, dry sensation, common signs has pharynx wall mucous hyperemia, in kermesinus, disperses protruding granule or in blocks as beading as seen at pharynx rear wall; have the vasoganglion of expansion around it, surface is sometimes with mucus or purulent secretion.
At present, treatment pharyngolaryngitis has two kinds of therapeutic schemes, a kind of is the antibiotic medicine of Western medicine, direct powerful kill bacteria and virus, but this mode easily causes the normal strain killed in human body, the side effect such as also easily to develop immunity to drugs; Another kind is the Chinese medicine such as Herba Menthae, Flos Lonicerae, Semen Sterculiae Lychnophorae with sore-throat relieving lung moistening effect, and the bottleneck throat discomfort but this kind of Chinese medicine can only be releived usually, cannot cure bottleneck throat inflammation.
Summary of the invention
Applicant is in Long-term clinical R&D process, invent a kind of Chinese medicine composition, composition improvement has been carried out on the bases such as traditional Flos Lonicerae, Semen Sterculiae Lychnophorae, thus has created synergy, effectively can treat the laryngopharyngitis because antibacterial etc. causes, there is the effect for the treatment of both the principal and secondary aspects of a disease.
The present invention is achieved through the following technical solutions:
Be used for the treatment of a Chinese medicine composition for pharyngolaryngitis, comprise following compositions, in mass fraction: Radix Rehmanniae 5-10, Flos Trollii 5-15, Radix Scrophulariae 5-12, Radix Ophiopogonis 5-12, Radix Sophorae Tonkinensis 5-12, Flos Lonicerae 5-10, Rhizoma Belamcandae 5-15, Semen Oroxyli 3-10, Radix Tinosporae 3-10, Radix Platycodonis 3-10, Semen Sterculiae Lychnophorae 5-15, Periostracum Cicadae 3-10, Radix Glycyrrhizae 2-8.
Preferably, each Ingredient Amount is Radix Rehmanniae 8, Flos Trollii 10, Radix Scrophulariae 8, Radix Ophiopogonis 8, Radix Sophorae Tonkinensis 8, Flos Lonicerae 8, Rhizoma Belamcandae 10, Semen Oroxyli 6, Radix Tinosporae 6, Radix Platycodonis 6, Semen Sterculiae Lychnophorae 10, Periostracum Cicadae 6, Radix Glycyrrhizae 5.
In mentioned component, utilize Flos Lonicerae, Semen Sterculiae Lychnophorae, Radix Glycyrrhizae to play sore-throat relieving lung moistening effect, alleviate the bad impression of patient fast; Utilize Radix Ophiopogonis, Radix Sophorae Tonkinensis, Semen Oroxyli, Periostracum Cicadae to play pharynx-clearing throat-benefiting, suppress the effect of dry mouth and tougue, utilize Radix Rehmanniae, Radix Scrophulariae, Rhizoma Belamcandae, Radix Tinosporae, Radix Platycodonis antimicrobial antiphlogistic, kill multiple fungus, coccus, virus etc. effect radical cure pathogenic former.Above-mentioned several composition synergism, creates effect for the treatment of both the principal and secondary aspects of a disease.
Accordingly, the invention discloses the preparation method of above-mentioned Chinese medicine composition, specifically by decocting the active component extracting each composition, in order to strengthen extraction effect, preferably at least decoct twice: decoct first and raw material is put into water soak, then boil with the medicinal liquid of big fire by immersion; Boil rear little fire and maintain boiling, then medicinal liquid is poured in container; Secondary decocts and residual residue is repeated said process; Merge the medicinal liquid decocted.
Wherein, decoct the water yield first and flooded powder 3-5cm, soak 20-60 minute, decocting time 20-30 minute; Secondary decocts the water yield and powder maintains an equal level, and soaks 20-60 minute, decocting time 25-35 minute.
In above-mentioned, alleged secondary decocts the water yield and powder and maintains an equal level and refer to the water surface and flooded powder a little or the two is fair.
In above-mentioned, alleged big fire, young man refer to the heating-up temperature of flame, big fire normally utilizes the flame of 200-300 DEG C heating that water is seethed with excitement rapidly, and young man normally utilizes the flame of 100-170 DEG C to be in micro-fluidized state to medicine pot small size heating maintenance medicinal liquid.
Because traditional Chinese medicine composition for treating pharyngolaryngitis of the present invention has good effect, therefore the invention also discloses the application of described Chinese medicine composition as treatment pharyngolaryngitis medicine.
Detailed description of the invention
Embodiment 1
Radix Rehmanniae 8g, Flos Trollii 10g, Radix Scrophulariae 8g, Radix Ophiopogonis 8g, Radix Sophorae Tonkinensis 8g, Flos Lonicerae 8g, Rhizoma Belamcandae 10g, Semen Oroxyli 6g, Radix Tinosporae 6g, Radix Platycodonis 6g, Semen Sterculiae Lychnophorae 10g, Periostracum Cicadae 6g, Radix Glycyrrhizae 5g, puts into marmite, adds clean cold water soak medicine, and amount of water, to flood powder 3cm, soaks 30 minutes.
Every agent medicine boils twice.First decoct and first with big fire, soaked medicine boiled after, use medium and small fire instead, maintain medicine boiling; Second decocts to add water and slightly flooded powder, and the duration and degree of heating is decocted with first.Medicine is started the clock after boiling.Medicine first decocts 20 minutes, and second decocts 18 minutes.
Imported by medicinal liquid in china bowl or glass drying oven, every auxiliary medicine is taken at twice, sooner or later respectively once, and totally 7 days courses for the treatment of.
Embodiment 2
Radix Rehmanniae 10g, Flos Trollii 15g, Radix Scrophulariae 5g, Radix Ophiopogonis 10g, Radix Sophorae Tonkinensis 10g, Flos Lonicerae 5g, Rhizoma Belamcandae 5g, Semen Oroxyli 8g, Radix Tinosporae 9g, Radix Platycodonis 3g, Semen Sterculiae Lychnophorae 5g, Periostracum Cicadae 3g, Radix Glycyrrhizae 4g, puts into marmite, adds clean cold water soak medicine, and amount of water, to flood powder 5cm, soaks 50 minutes.
Every agent medicine boils twice.First decoct and first with big fire, soaked medicine boiled after, use medium and small fire instead, maintain medicine boiling; Second decocts to add water and slightly flooded powder, and the duration and degree of heating is decocted with first.Medicine is started the clock after boiling.Medicine first decocts 30 minutes, and second decocts 30 minutes.
Then imported by medicinal liquid in china bowl or glass drying oven, every auxiliary medicine is taken at twice, sooner or later respectively once, and totally 7 days courses for the treatment of.
Embodiment 3
Radix Rehmanniae 6g, Flos Trollii 7g, Radix Scrophulariae 11g, Radix Ophiopogonis 6g, Radix Sophorae Tonkinensis 7g, Flos Lonicerae 10g, Rhizoma Belamcandae 12g, Semen Oroxyli 4g, Radix Tinosporae 5g, Radix Platycodonis 9g, Semen Sterculiae Lychnophorae 5g, Periostracum Cicadae 8g, Radix Glycyrrhizae 6g, puts into marmite, adds clean cold water soak medicine, and amount of water, to flood powder 4cm, soaks 40 minutes.
Every agent medicine boils twice.First decoct and first with big fire, soaked medicine boiled after, use medium and small fire instead, maintain medicine boiling; Second decocts to add water and slightly flooded powder, and the duration and degree of heating is decocted with first.Medicine is started the clock after boiling.Medicine first decocts 20 minutes, and second decocts 30 minutes.
Then imported by medicinal liquid in china bowl or glass drying oven, every auxiliary medicine is taken at twice, sooner or later respectively once, and totally 7 days courses for the treatment of.
In order to the effect of Chinese medicine composition of the present invention is described, applicant carried out following experiment.
1, study subject: select the age to be 7 ~ 75 years old, be that study subject 50 is routine without the acute/chronic pharyngitis of the main organs illness such as severe cardiac, liver, kidney, throat discomfort patient, study subject subjective symptom has pharyngalgia, itching throat, dry pharynx, foreign body sensation.There is at least one item in pharyngeal mucosa edema, mucous hyperemia, pharynx rear wall lymphocytic hyperplasia and secretions attachment on inspection.Wherein, male 25 example, women 25 example, the course of disease is the shortest 1 year, the longest 10 years.
2, instructions of taking: take the obtained Chinese medicine composition of embodiment 1 and using method thereof.
3, effect criterion: " the new Chinese medicine guideline of clinical investigations " issued with reference to Ministry of Public Health.
Effective: symptom alleviates or disappears, pharyngeal sign alleviates 2 grades.
Effective: symptom alleviates, pharyngeal sign alleviates 1 ~ 2 grade.
Invalid: symptom, sign are unchanged.
4, experimental result, according to different disease indexs, therapeutic effect is as follows:
Effect of table 1 Chinese medicine composition of the present invention
| Number of patients | Effective | Effectively | Invalid | Effective percentage |
| 50 | 44 | 5 | 1 | 98％ |
Table 2 cardinal symptom improves situation
| Symptom | Number of patients | Effective | Effectively | Invalid | Effective percentage |
| Laryngopharynx swelling and pain | 38 | 35 | 2 | 1 | 97.4％ |
| Foreign body sensation | 35 | 34 | 1 | 0 | 100％ |
| Dry mouth and tougue | 48 | 48 | 0 | 0 | 100％ |
| Throat is dry itches | 42 | 40 | 2 | 0 | 100％ |
The pharyngeal sign of table 3 improves situation
Claims (5)
1. be used for the treatment of a Chinese medicine composition for pharyngolaryngitis, it is characterized in that comprising following compositions, in mass fraction: Radix Rehmanniae 5-10, Flos Trollii 5-15, Radix Scrophulariae 5-12, Radix Ophiopogonis 5-12, Radix Sophorae Tonkinensis 5-12, Flos Lonicerae 5-10, Rhizoma Belamcandae 5-15, Semen Oroxyli 3-10, Radix Tinosporae 3-10, Radix Platycodonis 3-10, Semen Sterculiae Lychnophorae 5-15, Periostracum Cicadae 3-10, Radix Glycyrrhizae 2-8.
2. Chinese medicine composition according to claim 1, is characterized in that each Ingredient Amount is Radix Rehmanniae 8, Flos Trollii 10, Radix Scrophulariae 8, Radix Ophiopogonis 8, Radix Sophorae Tonkinensis 8, Flos Lonicerae 8, Rhizoma Belamcandae 10, Semen Oroxyli 6, Radix Tinosporae 6, Radix Platycodonis 6, Semen Sterculiae Lychnophorae 10, Periostracum Cicadae 6, Radix Glycyrrhizae 5.
3. the preparation method of the Chinese medicine composition of claim 1, is characterized in that at least decocting twice: decoct first and raw material is put into water soak, then boil with the medicinal liquid of big fire by immersion; Boil rear little fire and maintain boiling, then medicinal liquid is poured in container; Secondary decocts and residual residue is repeated said process; Merge the medicinal liquid decocted.
4. preparation method according to claim 3, is characterized in that decocting the water yield first flooded powder 3-5cm, soaks 20-60 minute, decocting time 20-30 minute; Secondary decocts the water yield and powder maintains an equal level, and soaks 20-60 minute, decocting time 25-35 minute.
5. the Chinese medicine composition of claim 1 is as the application for the treatment of pharyngolaryngitis medicine.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510005085.7A CN104547527A (en) | 2015-01-06 | 2015-01-06 | Traditional Chinese medicine composition for treating sphagitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510005085.7A CN104547527A (en) | 2015-01-06 | 2015-01-06 | Traditional Chinese medicine composition for treating sphagitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105560812A (en) * | 2016-01-04 | 2016-05-11 | 成都富豪斯生物科技有限公司 | Decoction drug for treating acute/chronic sphagitis and preparation method thereof |
| CN112190635A (en) * | 2020-10-13 | 2021-01-08 | 天津中医药大学第一附属医院 | Cicada throat spray and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2450047A1 (en) * | 2009-06-30 | 2012-05-09 | Hebei Yiling Medicine Research Institute Co., Ltd. | Pharmaceutical composition containing ephedrae for treating bronchitis and preparation method therefor |
| CN102861226A (en) * | 2012-09-29 | 2013-01-09 | 曲延丽 | Traditional Chinese medicine for treating sphagitis |
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2015
- 2015-01-06 CN CN201510005085.7A patent/CN104547527A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2450047A1 (en) * | 2009-06-30 | 2012-05-09 | Hebei Yiling Medicine Research Institute Co., Ltd. | Pharmaceutical composition containing ephedrae for treating bronchitis and preparation method therefor |
| CN102861226A (en) * | 2012-09-29 | 2013-01-09 | 曲延丽 | Traditional Chinese medicine for treating sphagitis |
Non-Patent Citations (3)
| Title |
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| 杨振萍等: "咽扁宁颗粒剂含化治疗急性咽喉炎疗效观察", 《陕西中医》 * |
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| 薛红等: "咽扁宁冲剂的薄层色谱鉴别及临床应用", 《制剂技术》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105560812A (en) * | 2016-01-04 | 2016-05-11 | 成都富豪斯生物科技有限公司 | Decoction drug for treating acute/chronic sphagitis and preparation method thereof |
| CN112190635A (en) * | 2020-10-13 | 2021-01-08 | 天津中医药大学第一附属医院 | Cicada throat spray and application thereof |
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