CN104397284A - Kidney tonifying and bone strengthening eleutherococcus senticosus health tea and preparation method thereof - Google Patents

Kidney tonifying and bone strengthening eleutherococcus senticosus health tea and preparation method thereof Download PDF

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CN104397284A
CN104397284A CN201410699178.XA CN201410699178A CN104397284A CN 104397284 A CN104397284 A CN 104397284A CN 201410699178 A CN201410699178 A CN 201410699178A CN 104397284 A CN104397284 A CN 104397284A
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parts
acanthopanax
kidney
root
health tea
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不公告发明人
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Qingdao Shen Da New And High Technology Development Corp Ltd
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Qingdao Shen Da New And High Technology Development Corp Ltd
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Abstract

The invention discloses kidney tonifying and bone strengthening eleutherococcus senticosus health tea, which comprises the following raw medicaments in parts by weight: 10 to 50 parts of eleutherococcus senticosus, 10 to 20 parts of achyranthes bidentata, 10 to 20 parts of psoralea corylifolia, 10 to 20 parts of solfiporia extensa, 10 to 20 parts of radix polygonum multiflorum preparata, 10 to 20 parts of davallia mariesii, 10 to 20 parts of mulberries, 10 to 20 parts of astragalus, 10 to 20 parts of schisandra chinensis, 10 to 20 parts of common club moss herb, 10 to 20 parts of herba taxilli, 10 to 20 parts of raspberries, 10 to 20 parts of clematis roots, 10 to 20 parts of rehmannia glutinosa, 10 to 20 parts of glossy privet fruits, 10 to 20 parts of salvia miltiorrhiza, 10 to 20 parts of epimedium herb, 10 to 20 parts of cortex moutan and 10 to 20 parts of curculigo orchioides. The eleutherococcus senticosus health tea contains multiple kinds of gypenosides, and a part of the gypenosides has biological activity similar to that of ginsenoside, so that the eleutherococcus senticosus healthc tea has the effects of improving the immunity (the immunity improvement effects of eleutherococcus senticosus gypenosides are better than those of ginseng), engendering essence, supplementing marrow, anti-aging, cultivating qi, tranquilization, improving sleep, supplementing the center, boosting essence, strengthening muscles and bones and enhancing willpower, is beneficial health drink, is nontoxic, and can be drunk for a long time as daily drink, and after the eleutherococcus senticosus health tea is taken for a long time, the body weight can be reduced, and life can be prolonged without harm.

Description

Acanthopanax root health tea of a kind of nourishing disney and strengthening bone and preparation method thereof
Technical field
The present invention relates to the medicinal preparation containing deriving from plant, animal or raw mineral materials medicine, particularly a kind of acanthopanax root health tea and preparation method thereof of nourishing disney and strengthening bone.
Background technology
Along with the quickening of the process of aging society, suffer from osteoporosis, the elderly of pelvic bone pain gets more and more.Traditional Chinese medicine is thought, the life of people, length, strong, always, all relevant with kidney.And the substantial connection of kidney and bone is summarized as " Shen controls bone ".The physiological function of Shen controls bone is actually essence in kidney and promotes that body growth grows a part for function.Once decline of kidney-QI, then can there is bone illness in kidney essence deficiency.
Kidney hides first acquired essence, and kidney essense turns to kidney qi, wherein to body have warm, excite, excited, evaporate, seal and hide and restrict the actor such as cold sensation of the genitalia and be referred to as kidney yang, be also called Yuanyang, kidney-Yang, kidney-yang; To body have moist, quiet, be shaped and suppress the excessively actor such as sun heat to be referred to as kidney yin, be also called Kidney-Yin, Kidney-Yin, true water.Kidney yang can promote metabolism and the gasification of human body, and promote that the change of essence and blood body fluid is given birth to and makes it to be converted into energy, make the progress faster of the various physiological activity of human body, heat production increases, in high spirits; Kidney yin then suppresses or the excessive metabolic processes of reducing human, make essence and blood body fluid be converted into energy to reduce, the process of the various physiological activity of human body slows down, heat production reduces relatively, and make gas be polymerized to shape and be essence and blood body fluid, spirit be also tending towards quiet in keep the two and oppose each other and yet also complement each other, common regulable control the function activity of human body and the metabolic process of essence and blood body fluid.
Self-evident clear since, the traditional Chinese medical science think always kidney be internal organs this, the root of 12 warps, the congenital foundation is kidney.Kidney and this same gas of the gate of vitality are the hinge of personal wane and wax of yin and yang.The yang-energy of the leading the whole body of kidney yang, the decline card of its then deficiency of yang of fire comes out one after another.Kidney-yang deficiency, i.e. kidney deficient and weak YANG QI are the diseases of kidney yang-energy exhaustion performance.Many by innate deficiency of YANG in the body, or old deficiency of the kidney, or prolonged illness is impairment of the kidney, or the factor such as excess of sexual intercourse,indulgence in sexual activities causes.Clinical manifestation: soreness of waist and knee joint, or back crymodynia, muscles and bones impotence is soft, aversion to cold and cold limbs, is very especially with lower limb; Vertigo, One's spirits are drooping, pale complexion or dark; The light fat tongue of tongue is white, forceless deep pulse; The easy impotence and premature ejaculation of the male sex, the easy fertility of women; Or stool lets out more than for a long time, diarrhea with undigested food, Diarrhoea; Or edema, be very below waist, by depression do not rise, very then belly distending pain, palpitaition is coughed and is breathed heavily.
Wilsonii has another name called slender acanthopanax ginseng, and modern medicine research proves that its special efficacy is substantially identical with ginseng can improving water flood, raising sleep quality, treatment hypertension, high fat of blood, diabetes, cerebral thrombus, coronary heart disease antirheumatic, anti-ageing, antifatigue, strengthens immunologic function.
Modern medicine research proves that the action character of wilsonii is substantially identical with ginseng, has and regulates body disorderly, make it to be tending towards normal function.Have good antifatigue effect, comparatively ginseng is remarkable, and significantly can improve hypoxia-bearing capability.Bowl spares, benefit essence, strong will, wines used as antirheumatic, strengthen the bone, blood circulation and promoting silt, the function such as stomach invigorating diuresis.Clothes of a specified duration " are made light of one's life by commiting suicide and are endured hardships ".Wilsonii contains noticeable composition---and eleutheroside, it can stimulate mind & body vigor.Numerous scientific publications about wilsonii demonstrates its antifatigue effect, strengthens endurance and ability, increases alert and resourceful and learning ability.Numerous usage obtains confirmation all in human experimentation.Wilsonii is rehabilitation after being ill, bears too much pressure or anxiety, works excessive, chronic disease cause weakly crowd and those need to reach very welcome self-medication medicine in the people on physiology and psychological performance peak.It has support immune system to have the report of considerable quantity to point out, recovers improper low blood pressure, improves the circulatory system, makes disorderly glycolipid metabolism normalization, liver, testis, anabolic effect of bone density and other vitals.
Does the tea that wilsonii is made have what effect and effect? radix Acanthopanacis senticosi tea is containing multiple glucoside, wherein part glucoside and panaxoside have similar physiologically active, there is antifatigue (antifatigue effect of eleutheroside is also stronger than ginseng), add essence benefit marrow and anti-ageing, soothing nerves and assisting sleep dormancy effect of fostering the spirit of nobility, being the useful health drink of drink, is the first-class natural beverage of the elderly and presenting friends.Effect of radix Acanthopanacis senticosi tea in ancient times just known by people, effect that " Mingyi Bielu " describes wilsonii to be had " bowl spares benefit essence, hard muscles and bones, strong will ".Therefore ancients have saying of " Ning get Yi, slender acanthopanax, not wanting the full car of gold and jade "; Wilsonii sees Shennong's Herbal, is classified as top grade; Top grade is refer to nontoxic, and for a long time clothes can be made light of one's life by commiting suicide, to be promoted longevity and harmless.Therefore radix Acanthopanacis senticosi tea also can as daily drink, can Long-Time Service.
Osteoporosis is mainly divided into primary and Secondary cases, and primary is except idiopathic, and be divided into I type and II type, I type is also called PMO, is high conversion hysteria, and main cause is that female hormone lacks; II type is also called senile osteoporosis, is low conversion hysteria, aging due to the age.Osteoporosis is caused by many factors, and its basic pathology mechanism is that in Bone m etabolism process, defect appears in bone information and osteoplastic coupling, causes alcium and phosphor metabolization in human body uneven, bone density is reduced gradually and the clinical symptoms that cause.Be used for preventing and treating osteoporotic medicine clinically to have: calcium preparation, include escape happy, Kai Sili, Caltrate D, happy power, calcium gluconate oral solution with effect, imperial prosperous calcium+D oral liquid, strength obtain calcium, huge can calcium and ultra micro calcium; Suppress bone information medicine, heir as pregnant in dehydrogenation, Premarin Tablet and Livial etc.; Bisphosphonates, as Fosamax, bone unicorn, Bang get Lin and Ji Li oxazepan; Osteogenic treatment medicine, as Tridin; Promote the vitamin medicaments of mineralising, as method energy (l alpha-hydroxy vitamin D 3), rocalcitrol (calcitriol), sprout lattice prosperous (Alfacalcidol), vertical celebrating (Alfacalcidol sheet).Only after fracturing because of osteoporosis, just need surgical intervention, its object is to treatment fracture, recover normal function as early as possible.Along with stepping into aging society, the elderly suffers from arthralgia and myalgia, and osteoporotic people gets more and more, and searches to the bottom, and is exactly that human body deficiency of kidney-QI causes.
Chinese traditional treatment is a dialectical process, and a lot of people does not understand oneself to be belong to what symptom, abuse tonic simply, result can only be controlled poorer and poorer.Symptom of suffering from a deficiency of the kidney utilizes modern instrument to detect and often comes to nothing, and doctor trained in Western medicine, to the not too wonderful works of nourishing disney and strengthening bone aspect, is also felt simply helpless to its treatment.Chinese medicine also exists dual regulation, when central concentration is too high, may causes certain antagonism, and make drug effect influenced; During low dosage, possible drug concentration is too low, causes drug effect and does not show.And for the traditional Chinese medical science, no matter be from traditional Chinese medical science mechanism, the formulation of institute's foundation or the formula components various aspects of medicine all do not have larger breakthrough, take mouthfeel not good, medicine is poor, take very inconvenient, the demand of various patient can not be met, the city life of modern high rhythm can not be met.
Summary of the invention
Technical problem to be solved by this invention is, current doctor trained in Western medicine, to the not too wonderful works of nourishing disney and strengthening bone aspect, is also felt simply helpless to its treatment.Chinese traditional treatment is a dialectical process, and a lot of people does not understand oneself to be belong to what symptom, abuse tonic simply, result can only be controlled poorer and poorer.Traditional Chinese medicine is thought, the life of people, length, strong, always, all relevant with kidney.And the substantial connection of kidney and bone is summarized as " Shen controls bone ".The physiological function of Shen controls bone is actually essence in kidney and promotes that body growth grows a part for function.Once decline of kidney-QI, then can there is bone illness in kidney essence deficiency.But Chinese medicine also exists dual regulation, when central concentration is too high, certain antagonism may be caused, and make drug effect influenced; During low dosage, possible drug concentration is too low, causes drug effect and does not show.Along with the quickening of the process of aging society, suffer from osteoporosis, the elderly of pelvic bone pain gets more and more, but inconvenience taken by Chinese medicine, and denouncing of smell poverty is not accepted by vast sufferer, and this contradiction more and more highlights.
For solving the problems of the technologies described above, the invention provides a kind of acanthopanax root health tea of nourishing disney and strengthening bone, acanthopanax root health tea described in it comprises the bulk drug of following parts by weight: wilsonii 10 ~ 50 parts, the root of bidentate achyranthes 10 ~ 20 parts, Psoralea corylifolia 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, RADIX POLYGONI MULTIFLORI PREPARATA 10 ~ 20 parts, the rhizome of davallia 10 ~ 20 parts, mulberries 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, lycopodium calvatum 10 ~ 20 parts, parasitic loranthus 10 ~ 20 parts, raspberry 10 ~ 20 parts, 10 ~ 20 parts, the root of Chinese clematis, 10 ~ 20 parts, cultivated land, the fruit of glossy privet 10 ~ 20 parts, the red sage root 10 ~ 20 parts, barrenwort 10 ~ 20 parts, the root bark of tree peony 10 ~ 20 parts, thizoma curculiginis 10 ~ 20 parts.
The acanthopanax root health tea of described nourishing disney and strengthening bone, the bulk drug of following parts by weight can be comprised: wilsonii 10 ~ 30 parts in acanthopanax root health tea described in it, the root of bidentate achyranthes 10 ~ 15 parts, Psoralea corylifolia 10 ~ 15 parts, 10 ~ 15 parts, Poria cocos, RADIX POLYGONI MULTIFLORI PREPARATA 10 ~ 15 parts, the rhizome of davallia 10 ~ 15 parts, mulberries 10 ~ 15 parts, the Radix Astragali 10 ~ 15 parts, 10 ~ 15 parts, the fruit of Chinese magnoliavine, lycopodium calvatum 10 ~ 15 parts, parasitic loranthus 10 ~ 20 parts, raspberry 10 ~ 20 parts, 10 ~ 20 parts, the root of Chinese clematis, 10 ~ 20 parts, cultivated land, the fruit of glossy privet 10 ~ 20 parts, the red sage root 10 ~ 20 parts, barrenwort 10 ~ 20 parts, the root bark of tree peony 10 ~ 20 parts, thizoma curculiginis 10 ~ 20 parts.
The acanthopanax root health tea of described nourishing disney and strengthening bone, the bulk drug of following parts by weight can also be comprised: wilsonii 10 ~ 40 parts in acanthopanax root health tea described in it, the root of bidentate achyranthes 10 ~ 20 parts, Psoralea corylifolia 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, RADIX POLYGONI MULTIFLORI PREPARATA 10 ~ 20 parts, the rhizome of davallia 10 ~ 20 parts, mulberries 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, lycopodium calvatum 10 ~ 20 parts, parasitic loranthus 10 ~ 15 parts, raspberry 10 ~ 15 parts, 10 ~ 15 parts, the root of Chinese clematis, 10 ~ 15 parts, cultivated land, the fruit of glossy privet 10 ~ 15 parts, the red sage root 10 ~ 15 parts, barrenwort 10 ~ 15 parts, the root bark of tree peony 10 ~ 15 parts, thizoma curculiginis 10 ~ 15 parts.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of acanthopanax root health tea of described nourishing disney and strengthening bone, and described in it, the preparation process of acanthopanax root health tea comprises following aspect:
A. first the acanthopanax plucked is cleaned and dry, then put into roller fixation machine and complete;
B. the electric frying pan put into by acanthopanax after terminating that completes stir-fries shaping;
C. shaping acanthopanax is put into and is carried camera Titian;
D. all the other bulk drugs described are prepared into granule or pulvis,
E. by the acanthopanax prepared and the granule obtained or pulvis mixing, pack shaping.
In described step a, can pluck wilsonii tender leaf in annual spring, first the free of contamination acanthopanax of anosis worm plucked be put into water and rinse, after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches collection; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 60-80 DEG C.
In described step b, naturally dry in the shade after the acanthopanax after completing can being taken out, put into large iron pan and knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 50-60 DEG C when becoming dark brown fry 30-45 minute shaping.
In described step c, the acanthopanax stir-fried can be dried naturally, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out.
In described steps d, the preparation method making granule when all the other bulk drugs is, all the other bulk drugs is put into the ethanol accounting for its quality 10 times amount, soak more than 24 hours, then heating and refluxing extraction 2 times, each 1 ~ 2 hour, No. 2 extracts are merged and leaves standstill, remove supernatant, merge extract, leave standstill 24 hours, remove supernatant, when to put into thickener reduced pressure concentration relative density be 80 DEG C 1.36 medicinal extract, stand for standby use, becomes component 1; Again the dregs of a decoction extracted are added 10 times of water gagings, then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use; Filter residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use; Filter residue adds water again, and half an hour is boiled in third time heating, filters; Three filtrates are combined, by filtered through gauze, in residue, add 50-60% ethanol; 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze; merge leaching liquor, be condensed into pasty state, become component 2; by component 1 and component also 2-in-1, then put into reduced pressure concentration tank, reclaim ethanol; when being concentrated into 90 DEG C, relative density is the medicinal extract of 1.50; be concentrated into every 1ml containing 0.1g crude drug amount, then add honey or dextrin mediation, put into the granule that granulator makes 0.1-0.2 centimetre.
In described steps d, the preparation method when all the other bulk drugs make pulvis is: all the other bulk drugs are added the water accounting for its quality 10 times amount, and then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use; Filter residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use; Filter residue adds water again, and half an hour is boiled in third time heating, filters; Three filtrates be combined, by filtered through gauze, add 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge leaching liquor, are condensed into pasty state, are then dried to powder.
In described step e, can will obtain granule or pulvis mixes with the acanthopanax that above-mentioned steps makes in steps d, after ultraviolet sterilization, pack packaging is shaping.
Advantageous Effects of the present invention is: traditional Chinese medicine is thought, the life of people, length, strong, always, all relevant with kidney.And the substantial connection of kidney and bone is summarized as " Shen controls bone ".The physiological function of Shen controls bone is actually essence in kidney and promotes that body growth grows a part for function.Once decline of kidney-QI, then can there is bone illness in kidney essence deficiency.Nourishing disney and strengthening bone of the present invention, the strong strong ridge of waist, liver-nourishing kidney-boosting, have temperature and not dry, the feature of tonify without causing stagnation, successful, to deficiency of kidney-QI or the osteoporosis caused of suffering from a deficiency of the kidney, arthralgia and myalgia has good curative effect.Radix Acanthopanacis senticosi tea is containing multiple glucoside, wherein part glucoside and panaxoside have similar physiologically active, there is raising immunity (the raising immunity of eleutheroside is also stronger than ginseng), add essence benefit marrow and anti-ageing, soothing nerves and assisting sleep dormancy effect of fostering the spirit of nobility, being the useful health drink of drink, is the first-class natural beverage of the elderly and presenting friends.Effect of radix Acanthopanacis senticosi tea in ancient times just known by people, effect that " Mingyi Bielu " describes wilsonii to be had " bowl spares benefit essence, hard muscles and bones, strong will ".Wilsonii sees Shennong's Herbal, is classified as top grade; Top grade is refer to nontoxic, and for a long time clothes can be made light of one's life by commiting suicide, to be promoted longevity and harmless.Therefore radix Acanthopanacis senticosi tea also can as daily drink, can Long-Time Service.
Detailed description of the invention
Though do not have the name of disease of primary osteoporosis in traditional Chinese medicine, relevant to change of age in "Nei Jing", essence in kidney degradation, the description from prosperity to decline of tooth, bone, develops the very identical bone density of the bone aging phenomenon occurred with this illness with the age.
" suffering from a deficiency of the kidney " that present society is often said, as seminal emission, positive fistula, premature ejaculation, frigidity, sterile, infertile etc., is actually suffering from a deficiency of the kidney of narrow sense.Sensu lato suffering from a deficiency of the kidney comprises a series of constitutional symptom.Chinese traditional treatment is a dialectical process, and a lot of people does not understand oneself to be belong to what symptom, abuse tonic simply, result can only be controlled poorer and poorer.
Self-evident clear since, the traditional Chinese medical science think always kidney be internal organs this, the root of 12 warps, the congenital foundation is kidney.Kidney and this same gas of the gate of vitality are the hinge of personal wane and wax of yin and yang.The yang-energy of the leading the whole body of kidney yang, the decline card of its then deficiency of yang of fire comes out one after another.Kidney-yang deficiency, i.e. kidney deficient and weak YANG QI are the diseases of kidney yang-energy exhaustion performance.Many by innate deficiency of YANG in the body, or old deficiency of the kidney, or prolonged illness is impairment of the kidney, or the factor such as excess of sexual intercourse,indulgence in sexual activities causes.Clinical manifestation: soreness of waist and knee joint, or back crymodynia, muscles and bones impotence is soft, aversion to cold and cold limbs, is very especially with lower limb; Vertigo, One's spirits are drooping, pale complexion or dark; The light fat tongue of tongue is white, forceless deep pulse; The easy impotence and premature ejaculation of the male sex, the easy fertility of women; Or stool lets out more than for a long time, diarrhea with undigested food, Diarrhoea; Or edema, be very below waist, by depression do not rise, very then belly distending pain, palpitaition is coughed and is breathed heavily.
Osteoporosis is mainly divided into primary and Secondary cases, and primary is except idiopathic, and be divided into I type and II type, I type is also called PMO, is high conversion hysteria, and main cause is that female hormone lacks; II type is also called senile osteoporosis, is low conversion hysteria, aging due to the age.Osteoporosis is caused by many factors, and its basic pathology mechanism is that in Bone m etabolism process, defect appears in bone information and osteoplastic coupling, causes alcium and phosphor metabolization in human body uneven, bone density is reduced gradually and the clinical symptoms that cause.Be used for preventing and treating osteoporotic medicine clinically to have: calcium preparation, include escape happy, Kai Sili, Caltrate D, happy power, calcium gluconate oral solution with effect, imperial prosperous calcium+D oral liquid, strength obtain calcium, huge can calcium and ultra micro calcium; Suppress bone information medicine, heir as pregnant in dehydrogenation, Premarin Tablet and Livial etc.; Bisphosphonates, as Fosamax, bone unicorn, Bang get Lin and Ji Li oxazepan; Osteogenic treatment medicine, as Tridin; Promote the vitamin medicaments of mineralising, as method energy (l alpha-hydroxy vitamin D 3), rocalcitrol (calcitriol), sprout lattice prosperous (Alfacalcidol), vertical celebrating (Alfacalcidol sheet).Only after fracturing because of osteoporosis, just need surgical intervention, its object is to treatment fracture, recover normal function as early as possible.Along with stepping into aging society, the elderly suffers from arthralgia and myalgia, and osteoporotic people gets more and more, and searches to the bottom, and is exactly that human body deficiency of kidney-QI causes.
Wilsonii has another name called slender acanthopanax ginseng, and modern medicine research proves that its special efficacy is substantially identical with ginseng can improving water flood, raising sleep quality, treatment hypertension, high fat of blood, diabetes, cerebral thrombus, coronary heart disease antirheumatic, anti-ageing, antifatigue, strengthens immunologic function.
Modern medicine research proves that the action character of wilsonii is substantially identical with ginseng, has and regulates body disorderly, make it to be tending towards normal function.Have good antifatigue effect, comparatively ginseng is remarkable, and significantly can improve hypoxia-bearing capability.Bowl spares, benefit essence, strong will, wines used as antirheumatic, strengthen the bone, blood circulation and promoting silt, the function such as stomach invigorating diuresis.Clothes of a specified duration " are made light of one's life by commiting suicide and are endured hardships ".Wilsonii contains noticeable composition---and eleutheroside, it can stimulate mind & body vigor.Numerous scientific publications about wilsonii demonstrates its antifatigue effect, strengthens endurance and ability, increases alert and resourceful and learning ability.Numerous usage obtains confirmation all in human experimentation.Wilsonii is rehabilitation after being ill, bears too much pressure or anxiety, works excessive, chronic disease cause weakly crowd and those need to reach very welcome self-medication medicine in the people on physiology and psychological performance peak.It has support immune system to have the report of considerable quantity to point out, recovers improper low blood pressure, improves the circulatory system, makes disorderly glycolipid metabolism normalization, liver, testis, anabolic effect of bone density and other vitals.
Does the tea that wilsonii is made have what effect and effect? radix Acanthopanacis senticosi tea is containing multiple glucoside, wherein part glucoside and panaxoside have similar physiologically active, there is antifatigue (antifatigue effect of eleutheroside is also stronger than ginseng), add essence benefit marrow and anti-ageing, soothing nerves and assisting sleep dormancy effect of fostering the spirit of nobility, being the useful health drink of drink, is the first-class natural beverage of the elderly and presenting friends.Effect of radix Acanthopanacis senticosi tea in ancient times just known by people, effect that " Mingyi Bielu " describes wilsonii to be had " bowl spares benefit essence, hard muscles and bones, strong will ".Therefore ancients have saying of " Ning get Yi, slender acanthopanax, not wanting the full car of gold and jade "; Wilsonii sees Shennong's Herbal, is classified as top grade; Top grade is refer to nontoxic, and for a long time clothes can be made light of one's life by commiting suicide, to be promoted longevity and harmless.Therefore radix Acanthopanacis senticosi tea also can as daily drink, can Long-Time Service.
Root of bidentate achyranthes filling liver kidney; Strengthening the bones and muscles; Activating blood to promote menstruation; Ignite (blood) descending; Inducing diuresis for treating strangurtia soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhoea; Postpartum abdominal pain due to blood stasis; Abdominal mass; Placenta retension; Heat is drenched; Blood drenches; Traumatic injury; Carbuncle is swollen dislikes sore; Abscess of throat.The root of bidentate achyranthes, walks and can mend, and property is apt to descending, therefore enters liver kidney.Main cold-dampness impotence numbness, spasm of limbs, the goinyalgia person of being unable to flex and stretch the extremities, liver spleen is suffered from a deficiency of the kidney, then cold-dampness heresy visitor form numbness, and sick spasm of limbs, goinyalgia is unable to flex and stretch the extremities.This property of medicine is walked and descending, and it can by cold-dampness except numbness also must.Top capping liver then muscle is relaxed, descending, manages knee, and promoting circulation of blood then pain stops.By vim and vigour, still cloud can lead to qi stagnation hemagglutination also." not Lu ": middle weak breath of curing the wound, male kidney yin disappears, and old man loses excessive, and bowl spares is absolutely continuous, fills out marrow, and except pain and pain along spinal column in brain, married woman's moon water is obstructed, and blood is tied, and benefit essence, Li Yin gas, only turns white.The effect of have diuresis, by force essence, stimulating the menstrual flow.Can relax the muscles and stimulate the blood circulation, specially control lumbocrural pain.
The rhizome of davallia is bitter, temperature.Return kidney, Liver Channel.The strong bone of function kidney tonifying, continues and hinders pain relieving.For lumbago due to the kidney deficiency, Hiccough and deaf, tooth mobility, falling winks frustrates, injured bone; Control alopecia areata outward, leucoderma." Japan hanako materia medica " carries it: control evil sore, lose rotten meat, desinsection.
The Radix Astragali is based on qi-restoratives, and energy invigorating qi for strengthening superficies, diuresis holder is malicious, apocenosis, expelling pus and promoting granulation.For insufficiency of vital energy and blood, sore caves in, purulence one-tenth is not burst or of a specified duration bursting does not hold back person.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration, i.e. the abscess suppuration myogenic of disunion for a long time.Modern medicine study shows, the Radix Astragali includes and multiple antibiotic effective ingredient, and can strengthen the immunologic function of body, therefore can also be used for the generation preventing some infectious disease." book on Chinese herbal medicine meets former " carries: " all void of Radix Astragali energy tonifying five zang organs, controls arteries and veins string spontaneous perspiration, rush down yin fire, remove lung heat, lossless, sends out, has sweat then to stop." be the good medicine promoting resistance and defence disease.
Raspberry is warm in nature; Sweet, sour; Return kidney, urinary bladder channel.Cure mainly: kidney-nourishing, controlling nocturnal emission with astringent drugs, contracting urine.For enuresis with renal asthenia, frequent urination, impotence and premature ejaculation, emission and spermatorrhea." Bencao Jingshu ": " raspberry, its main beneficial gas person, says beneficial vital essence also.Kidney storing essence, kidney receive gas, and vital essence is sufficient, then body is from light, send out white.Respectful main qi-restoratives of reviving is absolutely continuous, reinforcing yin essence Jianyang, smoothing skin, peace and internal organs.The main man's kidney-jing deficiency of Zhen Quan exhausts, impotence, woman's food have son.Large bright main five viscera settling, beneficial color, supports vital essence, long hair, Qiang Zhi.All get its kidney-nourishing and add essence, the adopted ear of sweet acid convergence." " property of medicine opinion " carry its: " main man's kidney-jing deficiency exhausts, woman's food have son.Main impotence.
Parasitic loranthus is bitter; Sweet; Property is put down.There is wines used as antirheumatic, liver and kidney benefiting, strengthening the bones and muscles, antiabortive effect.Enter the heart, kidney two warp.Function cures mainly: filling liver kidney; Strengthening the bones and muscles; Wines used as antirheumatic; Antiabortive.Main soreness of waist and knee joint; Muscles and bones impotence is weak; Limbs are hemiplegia; Arthralgia due to wind-dampness; Head is wrong dizzy; Fetal irritability, metrostaxis.For arthralgia due to wind-dampness, soreness and weakness of waist and knees, muscles and bones is unable, uterine bleeding through many, blood leaking in gestation, fetal irritability; Hypertension.
The root of Chinese clematis: Classification system: Clematis chinensis, belongs to medicinal plant, medicinal material Ji Yuan originates more, and the root of Chinese clematis that " Kaibao Bencao ", " Bencao Tujing ", herbal for Relief of Famines etc. are contained is goatweed; The root of Chinese clematis that " the southern regions of the Yunnan Province book on Chinese herbal medicine " is contained is feverfew, and use now mostly be " China's book on Chinese herbal medicine " the contained cohosh root of Chinese clematis, Clematis hexapetala etc.Domestic distributed more widely, its root and stem be used as medicine there is rheumatism, effect that the network that stimulates the menstrual flow, the bone that disappears are choked.In modern clinic practice, its new purposes is constantly found, as treatment gall stone, and calcaneal spur, talagia, the cancer of the esophagus etc.Dispel rheumatism, remove obstruction in channels to relieve pain, dissolving phlegm water, the loose hypochondriac lump.Cure mainly the stupid numbness of gout, arthralgia due to wind-dampness, extremity numbness, knee crymodynia, the contraction of muscle arteries and veins, joint stuffiness, beriberi, malaria, a lump in the abdomen causing distension and pain, lockjaw, tonsillitis, all bone sticking pharynxs.Tang Materia Medica: waist, kidney, pin knee, gather, all cold diseases in intestines, be not recovered for many years, the effect of clothes." Kaibao Bencao ": main all wind, Xuan Tongwu hides, and go in abdomen cold stagnant, septum cordis phlegm water amasss for a long time, abdominal mass Xuan tinea air parcel, bladder place purulence water unfit to drink, the cold pain of waist knee and treatment injured.
Cultivated land has another name called prepared rhizome of rehmannia or throws oneself on the ground, belong to goatweed, be a kind of first-class Chinese medicine, there is enriching yin effect of enriching blood, can be used for the deficiency of blood sallow, dizzy, palpitation and insomnia, irregular menstruation, the diseases such as uterine bleeding, also diseases such as can be used for hectic fever hectic fever due to yin, the night sweat of the deficiency of the kidney yin, pass out semen, quench one's thirst is one of asthenic symptoms class non-prescribed medicine medicine Liuwei Dihuang Wan main component.This quality is moistened into kidney, and kind nourishing kidney yin, life essence-filling, marrow-benefitting is the key medicine of tonifying kidney-yin.Ancients call it " large tonifying five zang organs is Kidney-Yin ", " the true water of large benefit ".Often be equal to use with Chinese yam, Fructus Corni, the treatment deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees, seminal emission, night sweat, tinnitus, deafness and quench one's thirst, can filling liver kidney, beneficial marrow, as Liuwei Dihuang Wan
The order that the fruit of glossy privet is used for the deficiency of liver-yin and kidney-yin is secretly failed to understand, hypopsia, poliosis, soreness of waist tinnitus and fever due to yin deficiency etc.This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, slowly must get effect.Control order secretly to fail to understand, often join cultivated land, matrimony vine is equal to use, controls poliosis, and often join the same use of the root of Chinese clematis, fever due to yin deficiency, often joins the root bark of Chinese wolf-berry.The deficiency of liver-yin and kidney-yin, Light-headedness, seminal emission tinnitus, soreness and weakness of waist and knees, poliosis, coronary heart disease, hyperlipidemia, hypertension, chronic hepatitis.The protective effect research of liver is thought, the fruit of glossy privet contains oleanolic acid, to rat skin lower injection, serum glutamic pyruvic transminase can be reduced, there is obvious protective effect to the hepatic injury of Carbon Tetrachloride Induced, and can liver cell regeneration be promoted. oleanolic acid also can make triglycerides accumulation minimizing in liver, degeneration of liver cells necrosis obviously alleviates, glycogen accumulation increases, serum γglobulin declines; Ultra microstructure visible liver cell mitochondrial swelling and endosomal vesicle sex change alleviate, hepatic tissue interstitial inflammation habituation.
The red sage root is bitter, is slightly cold.The thoughts of returning home, Liver Channel.Stasis-dispelling and pain-killing, activating blood to promote menstruation, clear away heart-fire relieving restlessness.For irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, and chest ventral spine pain, hot numbness pain, sore swells and ache, dysphoria and insomnia.For sternal rib hypochondriac pain, arthralgia due to wind-dampness, abdominal mass lumps, and sore swells and ache, fall fall forward grieved, irregular menstruation, through closing dysmenorrhoea, postpartum stasis of blood pain etc.Treatment sternal rib pain, abdominal mass caking, and irregular menstruation, through amenorrhoea pain, there is good effect.. " detailed outline " carries: the red sage root, and by " the sensible opinion of married woman " cloud, gynecopathy controlled by Siwu Tang, pays no attention to antenatal postpartum, how many through water, all can be general, and the only taste red sage root falls apart, and cures mainly identical with it.The lid red sage root can break place blood, mends new blood, peaceful tire, and fall stillborn foetus, only metrorrhagia stagnant under, menstruation regulating arteries and veins.Main Compositions of Radix Salviae Miltiorrhizae tanshinone has hemangiectasis, improves circulation, removes the effects such as intravascular coagulation, has effect of invigorating blood circulation trace, and can promote that liver blood circulates, be beneficial to liver cell regeneration.
Lycopodium calvatum nature and flavor toil temperature, enters Liver Channel.Expelling wind and clearing away cold. dehumidifying detumescence, stimulate the circulation of the blood and cause the muscles and joints to relax.For wind-cold-dampness arthralgia, muscle arteries and veins contraction pain carbuncle.Supplement to the Herbal: " owner suffers from wandering arthritis for a long time, and pin knee pain is cold, and munbness, strength is weak." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " lycopod, its property is walked and does not keep, and it does not float with sinking, and obtains betel nut good." " Hunan medicine will ": relax the muscles and stimulate the blood circulation, invigorating qi and dredging collateral.Control pain in the back, arthralgia, amenorrhoea.
The fruit of Chinese magnoliavine: the fruit of Chinese magnoliavine is used as medicine with rhizome.There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney benefiting functions.Be used for the treatment of weakness of the spleen and the stomach, fatigue and asthenia, dry food is few, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, and interior heat such as to be quenched one's thirst the disease.Very effective in cure for diabetes.The fruit of Chinese magnoliavine has hypotensive, hypoglycemic, reducing blood lipid, atherosclerosis, and delay senility and effect such as antibacterial grade, Fructus Schisandrae Polysaccharide has Immunestimulatory effect.For the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, and the labor of lung-kidney deficiency is coughed chronic cough etc.For weakness of the spleen and the stomach.Both tonifying spleen-yin, again beneficial temper, obtain dizzy, soreness and weakness of waist and knees for deficiency of kidney essence, poliosis and quenching one's thirst.The fruit of Chinese magnoliavine is strengthened the bone, and strong marrow, bleaches and send out; The cough phlegm be suitable for caused by lack of lung-YIN is few, dry cough without phlegm, the diseases such as hemoptysis.
Psoralea corylifolia taste is pungent; Bitter; Warm in naturely return through kidney; Pericardium; Spleen; Stomach; Lung channel function cures mainly: tonify the kidney and support yang; Promoting inspiration to relieve asthma; Warming spleen and stopping diarrha.The main insufficiency of the kidney yang; Below element deficiency and cold; Waist knee crymodynia; Impotence essence; Frequent micturition; The enuresis; The failure of the kidney in receiving air; Void is breathed heavily incessantly; Speen-kidney dificiency; Stool is rushed down for a long time." Bencao Jingshu ": Psoralea corylifolia, energy warming the kidney; Raw sun in the moon, the key medicine of sthenic fire benefit soil also.Its main general debility, the disease of lid edge internal lesion caused by overexertion, a lot of in speen-kidney dificiency, with its can warming the kidney, mend fire with the immature soil, then in kidney kidney-Yang be so incensed that mend and rise, then can digesting food, steam waste matter and change precise and tiny.Spleen-QI transporting the essence to the whole body is attributed to lung, supports the five internal organs with honor, therefore the labor of main the five internal organs.The seven human emotions hinder disease of viscera connecting with this channel.Wind empty cold person, because yang-energy is decayed, and the then air-cooled visitor that takes advantage of a weak point in opponent's defence so that marrow wound loses, the cold essence stream of kidney, and Shen controls bone store essential substances, marrow be essence this, the gas of kidney-Yang is solid, and namely, card is shown in, solid itself and yang-energy life, then front card removes in vain.Man is based on essence, and married woman is based on blood, and married woman vim and vigour person, also still man's sun kidney that declines is cold and be the degassed sunken disease of blood, and the cold essence stream of the kidney with man also.
Poria cocos taste is sweet, light, property is put down, and is used as medicine and has the function of clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Modern medicine study: Poria cocos energy enhanced machine body immunity function, pachymaran has significantly antitumor and protect the liver dirty effect.Poria cocos slightly sweet flavor is put down, and enters the heart, lung, the spleen channel.There is eliminating dampness and diuresis, strengthening the spleen and stomach, effect of antitoxic heart-soothing and sedative.Can control difficult urination, oedema turgor, phlegm and retained fluid is coughed inverse, vomits inverse, and vomiting during early pregnancy, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The Li Shui of Poria cocos, is reached by strong fortune spleen PFT, different from the Chinese medicine of other direct Li Shui.For splenasthenic diarrhea, the lower Poria cocos of band can invigorating the spleen, again can excreting dampness, and for having loose bowels caused by insufficiency of the spleen dysfunction of the spleen in transportation and transformation, being with down, application Poria cocos has the effect of giving consideration to both the incidental and fundamental, the compatibilities such as normal and Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam.Can be used as tonifying lung spleen, control the adjuvant of the deficiency of vital energy.
Barrenwort is pungent, sweet, warm, returns liver, kidney channel.Can tonify the kidney and support yang, strengthening the muscles and bones, dispels rheumatism, and is apt to control the insufficiency of the kidney yang, impotence and seminal emission, enuresis frequent micturition; Arthralgia due to wind-dampness, atrophic debility of bones paralysis disease." excessive sheep is fiery, and the main impotence of " herbal classic " medicine is hindered absolutely, and " solar corona " also its treatment of first speech man is positive absolutely, and woman is cloudy absolutely, then calling into the gate of vitality, benefit kidney-Yang person is also for " book on Chinese herbal medicine is stated " cloud.The lid gate of vitality be kidney-Yang in kidney, and namely the vigour of the person is also, its so-called exhausted yang exhaustion the moon, the not vigour of basis, how hiss in both withered.So-called beneficial strength, Qiang Zhi, and control cold air labor gas, muscles and bones contraction is anxious waits card, and all it helps the event of vigour.Old man dusk octogenarian, middle age forgetful, all Yuanyang decay and can not ascensionist also.Must know that this taste is to reduce to liter, it rises.
Root bark of tree peony clearing heat and cooling blood; Promoting blood circulation to remove blood stasis.Warm heat disease heat invading xuefen; Send out spot; Tell nosebleed; The pyreticosis later stage, hot Fu Yin divided heating; Deficiency of Yin osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhoea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.Control deficiency of blood overstrain dysphoria in chestpalms-soles limbs pain head dusk center of gravity alarmed and panicky cheek red dryness of the mouth and throat heating night sweat to subtract food and to fight mutually unsmooth menorrhea navel abdominal distention and pain chill and fever similar to malaria addicted to sleeping and blood-head; Control again the weak deficiency of Yin Rong Wei of unmarried girl's blood phlegm hectic fever human body of coughing of getting along well thin thin." herbal classic ": " main fever and chills, apoplexy Chi Zong, convulsion, frightened epilepsy perverse trend, except the hard hemostasis of disease stays house stomach, five viscera settling, treat carbuncle sore." " not Lu ": " except time gas headache, the objective hot exhaustion or lesion of the five internal organs, labor gas head pain in the back, wind is kept silent, insane disease." " property of medicine opinion ": " controls cold air, and loose all pains, control woman's passages through which vital energy circulates obstructed, blood drop Low Back Pain."
Mulberries nourishing yin and nourishing blood medicine; Promote the production of body fluid medicine; Aperitive.To enrich blood enriching yin, promote the production of body fluid and moisturize.For dizzy tinnitus, palpitation and insomnia, poliosis, Tianjin wound is thirsty, and interior heat is quenched one's thirst, blood deficiency and constipation.Tonifying liver, kidney-nourishing, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows liquid.Control liver-kidney Yin deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Both can food, can be used as medicine again, the traditional Chinese medical science thinks the sweet acid of mulberries taste, and cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of intelligence development of nourishing heart.There is enriching yin of enriching blood, promote the production of body fluid to quench thirst, the effects such as ease constipation is dry, cure mainly deficiency of YIN-blood and having a dizzy spell of causing, tinnitus palpitaition, irritated insomnia, soreness and weakness of waist and knees, poliosis, dry of quenching one's thirst, the diseases such as dry and hard excrement.
Thizoma curculiginis have tonify the kidney and support yang, benefiting essence-blood, strengthening the bones and muscles and promoting circulation of blood detumescence effect.Temperature kidney yang is strengthened; Dispel cold-dampness.Main impotence cold sperm; Aconuresis; Coldness and pain in the epigastrium; Soreness of waist and knee joint; Muscles and bones is weak; Lower limb contraction; Menopausal syndrome.On the normal and percentile impact of immunological function repression mouse T lymphocyte: adopt ester enzymatic assays mouse T lymphocyte percentage.Result proves, thizoma curculiginis can not improve normal mouse T lymphocyte percentage, but has obvious effect to the lymphocytic reduction of T of the suppressed mouse of caused by cyclophosphamide immunologic function.
The Chinese medicine fleece-flower root have Radix Polygoni Multiflori and RADIX POLYGONI MULTIFLORI PREPARATA point, direct slicing is used as medicine for Radix Polygoni Multiflori, dries be used as medicine for RADIX POLYGONI MULTIFLORI PREPARATA with black soya bean liquor after mixing steaming.The function of the two is different: the removing toxic substances of Radix Polygoni Multiflori function, the carbuncle that disappears, relax bowel, and is usually used in treatment scrofula sore carbuncle, rubella itch, the dry constipation of intestines; The filling liver kidney of RADIX POLYGONI MULTIFLORI PREPARATA function, benefiting essence-blood, black beard and hair, strengthening the bones and muscles, under sallow for the deficiency of blood, dizzy tinnitus, poliosis, soreness and weakness of waist and knees, extremity numbness, uterine bleeding band, chronic malaria body is empty etc.RADIX POLYGONI MULTIFLORI PREPARATA of the present invention is the good merchantable brand of invigrating kidney.
The specific embodiment of the invention:
Specific embodiment 1
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches collection; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 60-80 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out.Then other bulk drugs are made granule or pulvis, mixing, ultraviolet sterilization is packed.
Specific embodiment 2:
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches and collect general 5000g; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 60-80 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out, by all the other bulk drug roots of bidentate achyranthes 1500g, Psoralea corylifolia 1500g, Poria cocos 1500g, RADIX POLYGONI MULTIFLORI PREPARATA 1500g, rhizome of davallia 1500g, mulberries 1500g, Radix Astragali 1500g, fruit of Chinese magnoliavine 1500g, lycopodium calvatum 1500g, parasitic loranthus 1500g, raspberry 1500g, root of Chinese clematis 1500g, cultivated land 1500g, fruit of glossy privet 1500g, red sage root 1500g, barrenwort 1500g, root bark of tree peony 1500g, all the other bulk drugs are put into the ethanol accounting for its quality 10 times amount by thizoma curculiginis 1500g, soak more than 24 hours, then heating and refluxing extraction 2 times, each 1 ~ 2 hour, No. 2 extracts are merged and leaves standstill, remove supernatant, merge extract, leave standstill 24 hours, remove supernatant, when to put into thickener reduced pressure concentration relative density be 80 DEG C 1.36 medicinal extract, stand for standby use, become component 1, again the dregs of a decoction extracted are added 10 times of water gagings, then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use, filter residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use, filter residue adds water again, and half an hour is boiled in third time heating, filters, three filtrates are combined, by filtered through gauze, 50-60% ethanol is added in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge leaching liquor, be condensed into pasty state, become component 2, by component 1 and component also 2-in-1, then reduced pressure concentration tank is put into, reclaim ethanol, when being concentrated into 90 DEG C, relative density is the medicinal extract of 1.50, is concentrated into every 1ml containing 0.1g crude drug amount, then honey or dextrin mediation is added, put into the granule that granulator makes 0.1-0.2 centimetre, then mix the acanthopanax made, ultraviolet sterilization packs.
Specific embodiment 3
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches and collect general 4500g; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 60-80 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out; By all the other bulk drug roots of bidentate achyranthes 1200g, Psoralea corylifolia 1100g, Poria cocos 1200g, RADIX POLYGONI MULTIFLORI PREPARATA 1100g, rhizome of davallia 1200g, mulberries 1100g, Radix Astragali 1200g, fruit of Chinese magnoliavine 1100g, lycopodium calvatum 1200g, parasitic loranthus 1100g, raspberry 1200g, root of Chinese clematis 1200g, cultivated land 1200g, fruit of glossy privet 1200g, red sage root 1200g, barrenwort 1200g, all the other bulk drugs are added the water accounting for its quality 10 times amount by root bark of tree peony 1200g, thizoma curculiginis 1200g, then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use; Filter residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use; Filter residue adds water again, and half an hour is boiled in third time heating, filters; Three filtrates be combined, by filtered through gauze, add 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge leaching liquor, are condensed into pasty state, are then dried to powder.Then mix the acanthopanax made, ultraviolet sterilization packs.
Specific embodiment 4
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches and collect general 4000g; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 60-80 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out; By all the other bulk drug roots of bidentate achyranthes 1200g, Psoralea corylifolia 1100g, Poria cocos 1200g, RADIX POLYGONI MULTIFLORI PREPARATA 1100g, rhizome of davallia 1200g, mulberries 1100g, Radix Astragali 1200g, fruit of Chinese magnoliavine 1100g, lycopodium calvatum 1200g, parasitic loranthus 1100g, raspberry 1200g, root of Chinese clematis 1200g, cultivated land 1200g, fruit of glossy privet 1200g, red sage root 1200g, barrenwort 1200g, root bark of tree peony 1200g, thizoma curculiginis 1200g, all the other bulk drugs are put into the ethanol accounting for its quality 10 times amount and soak 1-3 hour, No. 2 extracts each 1 ~ 2 hour, are merged and leave standstill by heating and refluxing extraction 2 times; Above-mentioned two kinds of extracts are merged, decompression recycling ethanol to be concentrated into liquor strength be 0.6g crude drug/mL, after suction filtration, when the relative density of filtrate is about 20 DEG C 1.08; Be decompressed to 0.03-0.08MPa, temperature remains on 60-80 DEG C, and being concentrated into relative density is 1.20, the medicinal extract of temperature to 70 DEG C-80 DEG C, then adds honey or dextrin is in harmonious proportion, and puts into the granule that granulator makes 0.1-0.2 centimetre.Then mix the acanthopanax made, ultraviolet sterilization packs.
Pharmacological toxicity is tested
One, skin irritation test
1, experimental technique
Hair remover is evenly coated by guinea pig back backbone both sides, makes unhairing scope about 20 square centimeters.Clean hair remover returns cage to observe 24 hours, often organize cavy and be coated with the present invention's (pill) 4,8 and 12g respectively, respectively containing crude drug 92mg, 184mg and 368mg, another group is coated with the every twice-daily of solvent 0.8ml, continuous one week, after experiment terminates, cavy is put to death, the heart, liver, kidney and depilation skin do pathological examination.
2, result
Above-mentioned three groups of medication cavy trunks depilation district, having no local skin has oedema, hyperemia, erythema, blutpunkte and ulcer.Medication group cavy chroma of hair, ingest, the control group no significant difference such as four limbs are movable, histopathologic examination, the administration group heart, liver, kidney and depilation skin with contrast word more also no significant difference.
Result is pointed out, and the present invention, without local irritant effect, also has no general toxicity performance.Show invention formulation use safety.
Two, animal acute toxicity test research:
The present invention, through trial test, can not measure LD 50, therefore measures maximum dosage-feeding.Adopt rectal delivery, the maximum dosage-feeding on the one recording mouse is 62.7g/kg (in medicinal powder), be about 1567.5 times (people is in 60kg) intending clinical people's consumption, the maximum dosage-feeding 62.7g/kg (in medicinal powder) on the one of rat, is about 1567.5 times that intend clinical people's consumption.The equal Continuous Observation of animal used as test one week, its outward appearance sign, the state of mind, diet, drinking-water, ight soil etc. are showed no obvious abnormalities.At the end of experiment, all healthy survival of animal, body weight increases.
Three, long-term toxicity test for animals research:
One, test material and method
(1) test medicine: the made health protection tea of the embodiment of the present invention.
(2) animal used as test, healthy rat Wistar, body weight 100-130g, 140 male and female half and half, by sex and body weight random packet, four groups, often organize 35.1, take test medicine for 2,3 groups, dosage is respectively 9.6/kg/d, 6.4/kg/d, 3.2/kg/d.4 groups contrast to the distilled water of respective volume amount, the equal gavage enteral administration of rat, often organize and be once used in conjunction 6 months, put to death half, and all death in 12 days is observed in remaining 1/2 drug withdrawal.
Two, test index
(1) general status comprises body weight, diet, mood, movable energy.
(2) hemogram checking: red blood cell count(RBC), white blood cell count(WBC), platelet count, blood picture etc., quantitative hemoglobin counts.
(3) biochemical analysis, haemocyanin quantitatively, cholesterol, blood sugar quantitative.
(4) pathologic diagnosis: get half animal after experimental result and weigh, sacrificed by decapitation, gets blood, solution is treated others for earnest simultaneously, liver, kidney, lung, brain, spleen, stomach and intestine, bladder, adrenal gland does pathologic diagnosis.
Three, result of the test: show through rat chronic toxicity test, with the heavy dose of bowel lavage of the present invention six months, increases the growth of rat, body weight, all has no side effect to brain, Liver and kidney function.Do not find that infringement changes to each histoorgan of rat, the circulatory system, medication group compares no significant difference with control group.Illustrate that medicine of the present invention has warming and invigorating kidney Yang, beneficial gas, enriches blood, strengthens the drug effects such as metabolism, non-toxic.
Medicine and clinical trial
Along with China progresses into aging society, the bone metabolic diseases such as associated with osteoporosis disease become new study hotspot day by day.Traditional Chinese medicine " Shen controls bone " theory has long history, and instructs clinical practice always, and Kidney-Nourishing related to this occupies critical role in the treatment of bone metabolic disease.Intend from the critical role of kidney hydroxylase activity Bone m etabolism herein, one is done to the essence about Shen controls bone theory and inquires into, prove effect of nourishing disney and strengthening bone of the present invention.
One, materials and methods
(1) material
1. animal used as test cleaning grade male SD rat, 6 monthly ages.Body weight 320-350g.
2. key instrument 137Cs mono-radiation appliance, Garmma cell40, Canada; Borne densitometers, DPX-L-type, LUNAR company of the U.S.; Biomethanics instrument, INSTRON 5543, U.S.A..
3. main agents: Six-element bone-strengthening grain, electuary, the accurate word Z20025232 of traditional Chinese medicines, commercially available; The present invention forms, and Fang Yong: wilsonii 25g, root of bidentate achyranthes 11g, Psoralea corylifolia 13g, Poria cocos 11g, RADIX POLYGONI MULTIFLORI PREPARATA 12g, rhizome of davallia 10g, mulberries 11g, Radix Astragali 12g, fruit of Chinese magnoliavine 12g, lycopodium calvatum 13g, parasitic loranthus 13g, raspberry 10g, root of Chinese clematis 12g, cultivated land 12g, fruit of glossy privet 13g, red sage root 11g, barrenwort 11g, root bark of tree peony 12g, thizoma curculiginis 12g, is prepared into health protection tea by the method for embodiment 2, is provided by medicament chamber of the court.
(2) method
1. experiment grouping SD rat 40, is divided into 4 groups, control group (A), model group (B), Chinese drug-treated group (C), Western medicine group (D) at random, often organizes 10 (in experiments during A group gavage dead 2).
2. preserved skin under modeling and medication narcosis, the tincture of iodine, alcohol disinfecting, at vertebra both sides kidney body surface projection position row stringer otch.Expose both sides kidney, cover with physiological saline gauze, be fixed on mould by animal lateral position, stereotype blocks the tissue beyond kidney, expose kidney and be positioned over the internal radiation of B Cs mono-beam exposure apparatus, exposure dose is 15Gy (close rate is 0.91Gy/min).Carefully kidney is replied, layer-by-layer suture otch after irradiation.A group pull-out kidney does not irradiate, and puts back to the rear stitching edge of a knife.Postoperative every lumbar injection penicillin 80,000 unit of each operation group rat, continuous 3d.After irradiating 1 week starts drug treatment, and c group gives kidney-nourishing tcm drug oral liquid 1.34gkg of the present invention -1d (being equivalent to 25 times of adult's amount), D group sprouts the prosperous 0.1 μ gkg of lattice -1d -1, all use 0.5% celluloid sodium (CMC) to make gavage (1mL/ time) after suspension.Continuous 3 months; A, B two groups gives 0.5%CMC gavage (1ml/ only).
3. observation index and method
(1) bone density: get L ~ L5 lumbar vertebrae, removes Surrounding muscles, measures bone density (unit: g/cm with DPX-L-type dual intensity x line borne densitometers 2, accuracy of instrument is 1%).
(2) bone biomechanical: get rat L3 lumbar vertebrae, removing soft tissue, equating centrum upper and lower surface, is placed on biomethanics instrument and carries out lumbar vertebrae compression experiment, measures maximum compression load (ML); Separately get right side femur, remove soft tissue, applied biomechanics instrument carries out three-point bending test, measures gravity maximum load (ML).
(3) 1 α hydroxylase activities: often organize random selecting 5 animals used as test, left kidney is thoroughly poured into from sustainer with 50ml PBS, when kidney transfers pale to by mulberry, win and put in the ice-cold s-acetate bufer (pH7.4) of people; 20% (w/v) homogenate (operating) is prepared on ice, with standard items 25 (OH) D with Tris-acetatebufer 3be dissolved in 30 μ L ethanol, add in homogenate, often logical oxygen 1min on ice placed by pipe, and 37 DEG C of hatching 20min, add 5ml methyl alcohol/chloroform (2:1) cessation reaction.With put exempt from method detect hatch product la, 25 1 (OH) 2d 3, Y counter carries out quantitative analysis.The enzymatic reaction speed of unit of enzyme activity represents, i.e. pmolmg -1min -1.
4. with (x ± s), statistical procedures the data obtained all represents that input computer SPSS 11.0 software carries out One-way ANOVA and analyzes.
Two, result
(1) bone density change is compared with model group, control group, of the present invention group, the bone density of bone-strengthening grain group lumbar vertebrae is higher.Refer to table 1.
Table 1 is group In Rat Lumbar vertebra density ratio comparatively (DEXA method, g/cm respectively 2)
Group N Lumbar spine bmd
Control group 8 0.297±0.016**
Model group 10 0.275±0.014
Of the present invention group 10 0.323±0.021**
Bone-strengthening grain group 10 0.311±0.023**
Note: compare with model group, * P<0.05, * * P<0.01.(lower same)
(2) bone biomechanical change
Lumbar vertebrae and femur maximum load model group comparatively control group obviously reduce (P<0.01), and two medication groups obviously increase (P<0.05, P<0.01), no significant difference but between the two.Refer to table 2.
The comparison (N) of rat bone biomethanics respectively organized by table 2
(3) kidney 1 α hydroxylase activity change
1 α hydroxylase activity model group comparatively control group obviously reduces (P<0.05), of the present invention group comparatively model group obviously increase (P<0.05), bone-strengthening grain group compares no significant difference with model group.Refer to table 3.
Table 3 respectively group Rat renal 1 α hydroxylase activity compares (pmolmg -1min -1)
Group N 1 α hydroxylase activity
Control group 5 108.34±47.12*
Model group 5 65.57±5.23
Of the present invention group 5 105.81±45.24*
Bone-strengthening grain group 5 72.57±18.93
Three, discuss
Traditional Chinese medicine is thought, the life of people, length, strong, always, all relevant with kidney.And the substantial connection of kidney and bone is summarized as " Shen controls bone ".The physiological function of Shen controls bone is actually essence in kidney and promotes that body growth grows a part for function.Once decline of kidney-QI, then can there is bone illness in kidney essence deficiency.
Modern medicine thinks that the impact of kidney on bone tissue is mainly manifested in the activity of kidney 1 α hydroxylase and kidney in the regulation and control of alcium and phosphor metabolization.The important function of 1 α hydroxylase is its hydroxylation to vitamin D.What come from skin synthesis does not have biologically active with the vitamin D in food, through the hydroxylation of 25 hydroxylases in liver, must change into 25 (OH) D 3, after being transported to cortex renis, be positioned at the Intramitochondrial 25(OH)VD of Kidney anomaly 31 α hydroxylase hydroxylation is 1 α, 25 couples of hydroxyvitamin D 3and play physiological action.This D-hormone is relevant with the bone salts calmness of cartilage matrix calcification and bone tissue, and it can promote that enteron aisle is to the absorption of calcium, phosphorus, improves the level of blood calcium and serium inorganic phosphorus, is conducive to calcification and bone salts calmness.D-hormone makes calbindin increase, and optionally can promote the absorption of calcium in intestinal tube, but not promote the absorption of the calcium in sclerotin.On the other hand, kidney can by regulating the calcium phosphorus concentration in blood plasma to meet osteoplastic needs to heavily absorbing of the calcium phosphorus through renal excretion.Once the activity of kidney 1 α hydroxylase reduces, D-anhormonia, can cause bone metabolism disturbance and cause bone mineralising bad, osteoporosis etc.No matter sex clinically, the level of vitamin D declines gradually with advancing age, and the activity of kidney 1 α hydroxylase can reduce gradually, synthesizes 1 α, 25 couples of hydroxyvitamin D 3deterioration, cause intestines calcium uptake to reduce, skeletonization is not enough, and broken bone increases, and occurs osteoporosis.It is relevant that the generation of primary osteoporosis is advanced in years with Nian Gaoti, essence in kidney is not enough, and the reduction of kidney 1 α hydroxylase activity is the direct embodiment of essence in kidney deficiency.
Though do not have the name of disease of primary osteoporosis in traditional Chinese medicine, relevant to change of age in "Nei Jing", essence in kidney degradation, the description from prosperity to decline of tooth, bone, develops the very identical bone density of the bone aging phenomenon occurred with this illness with the age.The effect of kidney 1 α hydroxylase in Bone m etabolism is the important physiological Foundations of " Shen controls bone " theory.This experiment adopts the method for kidney radiation injury to prepare kidney Bone m etabolism damage model, result shows that injury of kidney causes 1 α hydroxylase activity to reduce, bone loss, bone density obviously reduces, lumbar vertebrae compression maximum load and femur gravity maximum load reduce, the bone strength of bone declines, and prompting injury of kidney causes kidney 1 α hydroxylase activity to be weakened, and causing D3 hormone to generate deficiency is the principle pathological mechanism that kidney Bone m etabolism damages.This research describes connecting each other between bone and kidney, kidney 1 α hydroxylase from pathologic angle.
This experimental result is pointed out, and application wilsonii, the root of bidentate achyranthes etc. are main kidney-nourishing tcm drug, and renal injury model animal 1 α hydroxylase hydroxylase activity is improved, and the maximum load of bone density, lumbar vertebrae and femur increases, and the quality of bone is improved.In kidney local, fibres visible hyperplasia under the kidney proximal tubule Electronic Speculum of rat model, mitochondrial swelling, electron density reduces, even vacuolar degeneration.Kidney-nourishing tcm drug can improve this situation, and the mitochondrial damage of kidney is repaired.And though control drug can make the maximum load of bone density, lumbar vertebrae and femur increase, but it is not obvious to the improvement result of kidney injury, to 1 α hydroxylase activity without obvious facilitation, illustrate that control drug action target spot is skeletal tissue local, and the effect link of kidney-nourishing tcm drug includes kidney and bone two aspects.Modern medicine research proves that the action character of wilsonii is substantially identical with ginseng, has and regulates body disorderly, make it to be tending towards normal function.Have good raising immunity, comparatively ginseng is remarkable, and significantly can improve hypoxia-bearing capability.Bowl spares, benefit essence, strong will, wines used as antirheumatic, strengthen the bone, blood circulation and promoting silt, the function such as stomach invigorating diuresis.Clothes of a specified duration " are made light of one's life by commiting suicide and are endured hardships ".Wilsonii contains noticeable composition---and eleutheroside, it can stimulate mind & body vigor.Numerous scientific publications about wilsonii has demonstrated it and has improved immunity, strengthens endurance and ability, increases alert and resourceful and learning ability.Numerous usage obtains confirmation all in human experimentation.Wilsonii is rehabilitation after being ill, bears too much pressure or anxiety, works excessive, chronic disease cause weakly crowd and those need to reach very welcome self-medication medicine in the people on physiology and psychological performance peak.It has support immune system to have the report of considerable quantity to point out, recovers improper low blood pressure, improves the circulatory system, makes disorderly glycolipid metabolism normalization, liver, testis, anabolic effect of bone density and other vitals.
Does the tea that wilsonii is made have what effect and effect? radix Acanthopanacis senticosi tea is containing multiple glucoside, wherein part glucoside and panaxoside have similar physiologically active, there is raising immunity (the raising immunity of eleutheroside is also stronger than ginseng), add essence benefit marrow and anti-ageing, soothing nerves and assisting sleep dormancy effect of fostering the spirit of nobility, being the useful health drink of drink, is the first-class natural beverage of the elderly and presenting friends.Effect of radix Acanthopanacis senticosi tea is in ancient times just known by people, and effect that " Mingyi Bielu " describes wilsonii to be had " bowl spares benefit essence, hard muscles and bones, strong will ", therefore radix Acanthopanacis senticosi tea also can as daily drink, can Long-Time Service.
Specific embodiment 1
Lee, man, 55, this patient at an early age waist be subject to hinder, and through many places, diagnosis and treatment are invalid, recently sensuously hemianesthesia, and soreness and weakness of waist and knees, connects building and step motionless leg, pelvic bone pain.Remove examination in hospital, osteoporosis 2 phase.Oneself buys calcium tablet, and drink milk is nourished.Calcium gluconate oral solution with effect, imperial prosperous calcium+D oral liquid, strength obtain calcium, huge energy calcium uses a lot, but feel to improve not quite.Do not like taste of traditional Chinese medicine, so seldom use Chinese medicine.Come here on May 27th, 2012 to go to a doctor, time medical, mood is depressed, and mood is dejected, is tormented severe by waist-leg disease pain.Look into poor appetite, four limbs are sleepy, and shape limb of trembling with fear is cold, and sallow complexion, clear abundant urine, tongue nature is light, and tongue is greasy in vain, and pulse sinks weak.Therapy: tonifying spleen and kidney, strong bone fills out marrow.
Choosing side: wilsonii 25g, root of bidentate achyranthes 11g, Psoralea corylifolia 13g, Poria cocos 11g, RADIX POLYGONI MULTIFLORI PREPARATA 12g, rhizome of davallia 10g, mulberries 11g, Radix Astragali 12g, fruit of Chinese magnoliavine 12g, lycopodium calvatum 13g, parasitic loranthus 13g, raspberry 10g, root of Chinese clematis 12g, cultivated land 12g, fruit of glossy privet 13g, red sage root 11g, barrenwort 11g, root bark of tree peony 12g, thizoma curculiginis 12g, be prepared into health protection tea by the method for embodiment 2.Every day works as tea-drinking, and after 20 days, sensation legs and feet are agile, and Low Back Pain takes a turn for the better, no longer difficult upstairs, continues use 40 days, not only physical rehabilitation, spiritual Jia Lang, and does not have lumbocrural pain again, recover as ordinary person, consolidate use again, strong.Follow up a case by regular visits to 1 year afterwards, have no recurrence.

Claims (10)

1. the acanthopanax root health tea of a nourishing disney and strengthening bone, it is characterized in that, described acanthopanax root health tea comprises the bulk drug of following parts by weight: wilsonii 10 ~ 50 parts, the root of bidentate achyranthes 10 ~ 20 parts, Psoralea corylifolia 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, RADIX POLYGONI MULTIFLORI PREPARATA 10 ~ 20 parts, the rhizome of davallia 10 ~ 20 parts, mulberries 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, lycopodium calvatum 10 ~ 20 parts, parasitic loranthus 10 ~ 20 parts, raspberry 10 ~ 20 parts, 10 ~ 20 parts, the root of Chinese clematis, 10 ~ 20 parts, cultivated land, the fruit of glossy privet 10 ~ 20 parts, the red sage root 10 ~ 20 parts, barrenwort 10 ~ 20 parts, the root bark of tree peony 10 ~ 20 parts, thizoma curculiginis 10 ~ 20 parts.
2. the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 1, it is characterized in that, described acanthopanax root health tea comprises the bulk drug of following parts by weight: wilsonii 10 ~ 50 parts, the root of bidentate achyranthes 10 ~ 15 parts, Psoralea corylifolia 10 ~ 15 parts, 10 ~ 15 parts, Poria cocos, RADIX POLYGONI MULTIFLORI PREPARATA 10 ~ 15 parts, the rhizome of davallia 10 ~ 15 parts, mulberries 10 ~ 15 parts, the Radix Astragali 10 ~ 15 parts, 10 ~ 15 parts, the fruit of Chinese magnoliavine, lycopodium calvatum 10 ~ 15 parts, parasitic loranthus 10 ~ 20 parts, raspberry 10 ~ 20 parts, 10 ~ 20 parts, the root of Chinese clematis, 10 ~ 20 parts, cultivated land, the fruit of glossy privet 10 ~ 20 parts, the red sage root 10 ~ 20 parts, barrenwort 10 ~ 20 parts, the root bark of tree peony 10 ~ 20 parts, thizoma curculiginis 10 ~ 20 parts.
3. the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 1, it is characterized in that, described acanthopanax root health tea comprises the bulk drug of following parts by weight: wilsonii 10 ~ 50 parts, the root of bidentate achyranthes 10 ~ 20 parts, Psoralea corylifolia 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, RADIX POLYGONI MULTIFLORI PREPARATA 10 ~ 20 parts, the rhizome of davallia 10 ~ 20 parts, mulberries 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, lycopodium calvatum 10 ~ 20 parts, parasitic loranthus 10 ~ 15 parts, raspberry 10 ~ 15 parts, 10 ~ 15 parts, the root of Chinese clematis, 10 ~ 15 parts, cultivated land, the fruit of glossy privet 10 ~ 15 parts, the red sage root 10 ~ 15 parts, barrenwort 10 ~ 15 parts, the root bark of tree peony 10 ~ 15 parts, thizoma curculiginis 10 ~ 15 parts.
4. the preparation method of the acanthopanax root health tea of nourishing disney and strengthening bone as described in any one of claims 1 to 3 item, it is characterized in that, the preparation process of described acanthopanax root health tea comprises following aspect:
A. first the acanthopanax plucked is cleaned and dry, then put into roller fixation machine and complete;
B. the electric frying pan put into by acanthopanax after terminating that completes stir-fries shaping;
C. shaping acanthopanax is put into and is carried camera Titian;
D. all the other bulk drugs described are prepared into granule or pulvis,
E. by the acanthopanax prepared and the granule obtained or pulvis mixing, pack shaping.
5. the preparation method of the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 4, it is characterized in that, in described step a, annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water to rinse, after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches collection; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 60-80 DEG C.
6. the preparation method of the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 4, it is characterized in that, in described step b, acanthopanax taking-up after completing is dried in the shade afterwards naturally, put into large iron pan to knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 50-60 DEG C when becoming dark brown fry 30-45 minute shaping.
7. the preparation method of the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 4, is characterized in that, in described step c, the acanthopanax stir-fried is dried naturally, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out.
8. the preparation method of the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 4, it is characterized in that, in described steps d, the preparation method making granule when all the other bulk drugs is, all the other bulk drugs are put into the ethanol accounting for its quality 10 times amount, soak more than 24 hours, then heating and refluxing extraction 2 times, each 1 ~ 2 hour, No. 2 extracts are merged and leaves standstill, remove supernatant, merge extract, leave standstill 24 hours, remove supernatant, when to put into thickener reduced pressure concentration relative density be 80 DEG C 1.36 medicinal extract, stand for standby use, becomes component 1; Again the dregs of a decoction extracted are added 10 times of water gagings, then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use; Filter residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use; Filter residue adds water again, and half an hour is boiled in third time heating, filters; Three filtrates are combined, by filtered through gauze, in residue, add 50-60% ethanol; 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze; merge leaching liquor, be condensed into pasty state, become component 2; by component 1 and component also 2-in-1, then put into reduced pressure concentration tank, reclaim ethanol; when being concentrated into 90 DEG C, relative density is the medicinal extract of 1.50; be concentrated into every 1ml containing 0.1g crude drug amount, then add honey or dextrin mediation, put into the granule that granulator makes 0.1-0.2 centimetre.
9. the preparation method of the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 4, it is characterized in that, in described steps d, preparation method when all the other bulk drugs make pulvis is: all the other bulk drugs are added the water accounting for its quality 10 times amount, then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use; Filter residue adds water, and second time heating, boils 45 minutes, and filter, filtrate is for subsequent use; Filter residue adds water again, and half an hour is boiled in third time heating, filters; Three filtrates be combined, by filtered through gauze, add 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge leaching liquor, are condensed into pasty state, are then dried to powder.
10. the preparation method of the acanthopanax root health tea of nourishing disney and strengthening bone according to claim 4, is characterized in that, in described step e, will obtain granule in steps d or pulvis mixes with the acanthopanax that above-mentioned steps makes, after ultraviolet sterilization, pack packaging is shaping.
CN201410699178.XA 2014-11-27 2014-11-27 Kidney tonifying and bone strengthening eleutherococcus senticosus health tea and preparation method thereof Pending CN104397284A (en)

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