CN104189586A - Agent for relieving hysterical somatic disorders and preparation method thereof - Google Patents

Abstract

The invention discloses an agent for relieving hysterical somatic disorders. The agent is prepared from the following raw material medicines in parts by weight: 12-20 parts of lotus leaf, 10-14 parts of pinellia ternate, 6-10 parts of ginseng fruit, 8-12 parts of dried tangerine or orange peel, 30-40 parts of Chinese yam, 10-18 parts of rhizoma alismatis, 25-45 parts of indigo naturalis, 3-8 parts of keel, 22-36 parts of oyster, 6-12 parts of red flower, 6-15 parts of apocynum venetum, 6-15 parts of ligusticum, 9-16 parts of blackend swallowwort root, 6-12 parts of white baneberry, 6-15 parts of tangerine leaf, 5-12 parts of radix rehmanniae, 9-18 parts of medicinal cyathula root, 6-10 parts of Scrophularia ningpoensis, 5-9 parts of Radix Ophiopogonis, 8-16 parts of Marasmius androsaceus, 6-15 parts of Gardenia, 6-12 parts of caulis bambusae in taeniam, 5-15 parts of fried fructus aurantii and 3-6 parts of Licorice Roots Northwest Origin. The agent has the beneficial effects that the selected materials are traditional Chinese medicine materials and do not have any toxic or side effect; the formula performs comprehensive treatment due to the combined actions of multiple Chinese herbal medicines, so that the active ingredients of the medicines rapidly penetrate into lesions, the yin-yang disharmony symptoms of spleen, heart, liver and kidney are improved, and the functions of human body are wholly regulated. The agent is prepared by integrating the advantages of traditional Chinese medicine therapy in treatment of the hysterical somatic disorders and has the advantages of fast effectiveness, short course of treatment, low cost and the like.

Description

Alleviate medicament and the preparation method of hysteric conversion

Technical field

The present invention relates to Chinese medicine field, particularly relate to a kind of medicament and preparation method of alleviating hysteric conversion.

Background technology

Hysteric conversion is due to obvious psychological factor, as life events, and intrapsychic conflict or strong emotional experience, one group of disease that hint or self suggestion etc. cause.The clinical manifestation of hysteric conversion mainly contains following three aspects.(1) abnormal psychogenic pain.Abnormal psychogenic pain is the acute severity headache that causes of psychological factor or the pain at other positions of body, or be serious or bothersome chronic pain for a long time.Check without degree and the organic disease of corresponding organic disease or pain unbecoming.Or skin is touched, feel insufferable pain.Paraesthesia has " hysteria helmet " and " globus hystericus ", and the former performance is that patient feels that head presses, and as putting on a steel helmet, has a kind of special sensation; Globus hystericus is that patient often feels pharyngeal have foreign body sensation or sense of obstruction, as there being a ball to block at bottleneck throat.(2) hyperesthesia and anesthesia and special sense obstacle.Hyperesthesia shows as touching responsive especially, and slight stroking can cause and have an intense pain.Anesthesia shows as part or whole skin impercipience or is half body analgesis.Sometimes be glove-like or ankle socks type anesthesia, its scope is inconsistent with neural distribution.Special sense obstacle comprises visual disorder and dysacousis, and patient shows as paroxysmal hearing disability or blind.Sometimes also show as that amblyopia, tubulose are spied on, monocular diplopia.Listen, VEP inspection is normal, it is normal that symptom can be recovered suddenly.(3) autonomous (plant) delayed ischemic neurological deficits.Can show as anorexia, voracity, vomiting, singultus, Hyperventilation and vasomotor disturbance, the appearance of symptom is all relevant with psychological factor, can produce or disappear because of hint.Wherein common with hysteria singultus, account for 4.5%.Usually occur within a certain period of time, show as obstinate singultus, sound is loud and clear, successively, relevant with environmental factors, and when noticeable, frequently, when nobody notes, singultus can reduce or disappear in outbreak, and patient does not agonize with this.Vomiting mostly is intractable, after food, tells, and tells front nothing and feels sick, and there is no difficulty while telling.。In addition,, under psychological factor impact, still can there is the symptom of the neural and endocrine dysfunction such as esohagismus, enteroparalysis, tachycardia, out of breath, frequent micturition, urgent micturition, pseudo-fetus autonomous (plant).Hysteric conversion can be brought out by hint, also can disappear by implying, has the tendency of outbreak repeatedly.Think that cultural lag area prevalence is higher more, age of onset in women between 16-35 year more than male,

The Therapeutic Method of hysteric conversion mainly contains following several: one, psychotherapy: the substantially sub-measure that is treatment hysteria, mainly comprise following several respects: 1, suggestive treatment: be the effective measures of eliminating hysteric conversion, be specially adapted to the patient of Acute onset.In the time of can being divided into awakening, hint and hypnotic suggestion are two kinds.Patient's an urgent demand therapist, under wakefulness, by verbal suggestion, or coordinates suitable physical therapy, acupuncture or massage, can obtain good result.The course of disease is longer, and the case that the cause of disease is unclear often need to be eliminated patient's psychological resistance by medicine or language hypnotherapy, just can obtain better effects.2, hypnotherapy: under psycheism, can make the traumatic experience passing into silence reappear, be subject to oppressive emotion and obtain release, thereby reach symptomatolytic object.Under hypnosis or wakefulness, to pour out its heart depressed for guiding patient, makes the Therapeutic Method that comes to harm or oppressive love knot is outwards led off, is called catharsis.The hysteria patient outstanding to dysthymic disorder can achieve good results.3, explanatory psychotherapy: main purpose is: guide patient to be correctly familiar with and treat pathogenic Nervous and Mental Factors, the character of understanding disease, helps patient to analyze the defect that individual character exists, and the approach that overcomes defect of personality is with square turbid.Be applicable to the various hysteria except the sick period of disease of hysteria disposition god.4, analytical psychotherapy: seek emphatically patient's unconscious motivation, guiding patient is familiar with unconscious motivation to healthy impact, and is eliminated.Mainly apply to hysterical amnesia, multiple personality and various physical obstacle.Can take psycho analysis technology or comprehension therapy.5, the behavior therapy.6, family therapy.Two, medicine and physiotherapy.1, when Drug therapy hysteria twilight state, psychotic state or convulsion, regular spiritual healing beyond affordability.2, naturopathy: acupuncture or electrical excitation treatment, to dysfunctions such as hysterical paralysis, deafness, blind, aphonia or limbs twitches, all can have good result.

Publication number CN 1308959 A(application numbers 01100556.4) Chinese patent literature discloses a kind of medicine-' Yishenjieyu ' for the treatment of mental diseases (psychosis etc.), this prescription is comprised of the raw material of following weight portion proportioning: Radix Bupleuri 10-20, Rhizoma Cyperi 10-20, Radix Angelicae Sinensis 6-15, Radix Paeoniae Alba 6-15, Rhizoma Atractylodis Macrocephalae 6-15, Poria 6-15, Fructus Hordei Germinatus 15, Rhizoma Curcumae 6-15 Rhizoma Sparganii 6-15, the Sheng Huo processed with wine 2-9 of Radix Et Rhizoma Rhei, Rhizoma Pinelliae 6-18, Pericarpium Citri Reticulatae 6-15, Radix Glycyrrhizae 6-10, Magnetitum 30-90, Radix Polygalae 6-15, Rhizoma Acori Graminei 6-15, Radix Curcumae 6-15, Concha Margaritifera 10-30, Fructus Alpiniae Oxyphyllae 6-15, Fructus Jujubae 10-20, Fructus Aurantii Immaturus 6-15, Caulis Bambusae In Taenia 6-15, Endothelium Corneum Gigeriae Galli 15, Rhizoma Zingiberis Recens 0-10, Arisaema Cum Bile 0-15, Radix Ginseng 0-10, Moschus 0-3, Styrax 0-3.Publication number CN 101433645 A(application numbers 200810042683.1) Chinese patent literature discloses Chinese medicine preparation of a kind of antidepressant and irritable psychological disorder and preparation method thereof, this medicament is by Rhizoma Pinelliae Preparata 9-15 part, Rhizoma Arisaematis (processed) 9-15 part, Pericarpium Citri Reticulatae 9-15 part, Poria 9-30 part, Radix Bupleuri 6-9 part, Radix Paeoniae Alba 9-18 part, Rhizoma Coptidis 3-6 part, Radix Angelicae Sinensis 9-15 part, Rhizoma Atractylodis Macrocephalae (parched) 9-15 part, Os Draconis 15-30 part, Radix Glycyrrhizae Preparata 6-9 part forms.Publication number CN 103169890 A(application numbers 201310129294.3) Chinese patent literature discloses a kind of medicine for the treatment of social phobia, and it is to be made by the raw material of following weight proportion: 100 parts, Radix Rehmanniae Preparata, 80 parts of Radix Pseudostellariaes, 80 parts of Rhizoma Dioscoreaes, 80 parts of Poria cum Radix Pinis, 50 parts of Radix Asparagis, 50 parts of Radix Ophiopogonis, 50 parts of Radix Polygalaes, 50 parts of Semen Ziziphi Spinosaes, 50 parts of Arillus Longans, 50 parts of Fructus Aurantii Immaturuss, 50 parts of Caulis Bambusae In Taenia, 5 parts, Cinnabaris, 50 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Angelicae Sinensis, 30 parts of Fructus Schisandrae Chinensis, 50 parts of Fructus Crataegis, 30 parts of Radix Glycyrrhizae Preparatas.

In a word, Chinese medicine is being obtained good curative effect aspect treatment primary disease, but also has some problems: the shortcomings such as not ideal enough to the treatment of hysteric conversion disease clinically, the treatment phase is long, effective percentage is low, easy recurrence.There is no at present the specific drug of curing completely.

Summary of the invention

For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, easy medicament of the alleviation hysteric conversion of clothes and preparation method thereof for a long time.This curative effect of medicine is definite and have no side effect.

Technical scheme of the present invention is:

The medicament of alleviating hysteric conversion, is prepared from by following bulk drugs, is weight portion: Folium Nelumbinis 12-20, Rhizoma Pinelliae 10-14, Rhizoma Tupistrae Chinensis 6-10, Pericarpium Citri Reticulatae 8-12, Rhizoma Dioscoreae 30-40, Rhizoma Alismatis 10-18, Indigo Naturalis 25-45, Os Draconis 3-8, Concha Ostreae 22-36, Flos Carthami 6-12, Herba Apocyni veneti 6-15, Rhizoma Ligustici 6-15, Radix Cynanchi Atrati 9-16, Radix Delphinii pogonanthi 6-12, Folium Citri tangerinae 6-15, Radix Rehmanniae 5-12, Radix Cyathulae 9-18, Radix Scrophulariae 6-10, Radix Ophiopogonis 5-9, Marasmius equicrinis Muell. 8-16, SHANZHIZI 6-15, Caulis Bambusae In Taenia 6-12, Fructus Aurantii (parched) 5-15, Radix Glycyrrhizae 3-6.

In preferred scheme, Folium Nelumbinis 14-18, Rhizoma Pinelliae 11-13, Rhizoma Tupistrae Chinensis 7-9, Pericarpium Citri Reticulatae 9-11, Rhizoma Dioscoreae 33-37, Rhizoma Alismatis 12-16, Indigo Naturalis 30-40, Os Draconis 4-7, Concha Ostreae 25-33, Flos Carthami 8-10, Herba Apocyni veneti 9-12, Rhizoma Ligustici 9-12, Radix Cynanchi Atrati 11-14, Radix Delphinii pogonanthi 7-11, Folium Citri tangerinae 8-13, Radix Rehmanniae 7-10, Radix Cyathulae 12-15, Radix Scrophulariae 7-9, Radix Ophiopogonis 6-8, Marasmius equicrinis Muell. 10-14, SHANZHIZI 9-12, Caulis Bambusae In Taenia 8-10, Fructus Aurantii (parched) 7-13, Radix Glycyrrhizae 4-5.

Be more preferably Folium Nelumbinis 16, the Rhizoma Pinelliae 12, Rhizoma Tupistrae Chinensis 8, Pericarpium Citri Reticulatae 10, Rhizoma Dioscoreae 35, Rhizoma Alismatis 14, Indigo Naturalis 35, Os Draconis 5.5, Concha Ostreae 29, Flos Carthami 9, Herba Apocyni veneti 10.5, Rhizoma Ligustici 10.5, Radix Cynanchi Atrati 12.5, Radix Delphinii pogonanthi 9, Folium Citri tangerinae 10.5, Radix Rehmanniae 8.5, Radix Cyathulae 13.5, Radix Scrophulariae 8, Radix Ophiopogonis 7, Marasmius equicrinis Muell. 12, SHANZHIZI 10.5, Caulis Bambusae In Taenia 9, Fructus Aurantii (parched) 10, Radix Glycyrrhizae 4.5.

The present invention also provides the preparation method of aforementioned medicament being made to pharmaceutically acceptable decoction and thick paste agent.

The preparation method of described decoction is:

(1) Indigo Naturalis, Os Draconis are pulverized, sieved, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, adding distil water soaks 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, 110 ℃ of sterilizings, cooling encapsulation, obtains.

In the preparation method of above-mentioned alleviation hysteric conversion decoction, preferred scheme is in step (1), to cross 110-160 mesh sieve (the preferred 120-150 of mistake mesh sieve, was more preferably 140 mesh sieves).

In the preparation method of above-mentioned alleviation hysteric conversion decoction, preferred scheme is that in step (2), the temperature of distilled water is 30-50 ℃ (preferably temperature is 35-45 ℃, and being more preferably temperature is 40 ℃).

In the preparation method of above-mentioned alleviation hysteric conversion decoction, preferred scheme is that in step (4), sterilization time is 1-4 hour (preferably sterilization time is 2-3 hour, and being more preferably sterilization time is 2.5 hours).

The preparation method of described thick paste agent is:

(1) Indigo Naturalis, Os Draconis are pulverized, sieved, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, adding distil water soaks 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add step (1) gained fine powder, mix, cooling, obtain thick paste agent.

The application of medicament described in the present invention also provides when the medicine of hysteric conversion is alleviated in preparation.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Folium Nelumbinis: base is former: be the leaf of nymphaeaceae plant lotus.Character: dry leaf is folded into semicircle or fan-shaped is conventionally complete or slightly broken.After mounted blade, be buckler-shaped, more than 30 centimetres of diameters.Positive dark green or brown-green, the short and thick glandular hair of adularescent: back side lark or light gray green are smoothly glossy; There is the petiole residual base of a projection at center; Full edge; Vein is obvious, by center, outwards radiated, and mitogenetic most thready pulse.Chemical analysis: leaf is containing nuciferine, nuciferine, miltanthin, armepavine, pronuciferine (+)-Pronuciferine, N-demethyl nuciferine, D-N-methyl coclaurine, anonaine, liriodendrin, Quercetin, Isoquercitrin, lotus glycoside, tartaric acid, citric acid, malic acid, gluconic acid, oxalic acid, succinic acid, tannin.Also contain the alkaline components of resisting mitosis effect.Nature and flavor: bitterness, flat.Gui Jing: enter the heart, liver, spleen channel.Function cures mainly: clearing away summer-heat and eliminating dampness, rises and send out sliding sun, hemostasis.Control diarrhea due to summer heat and dampness, dizzy, aqueous vapor edema, thunder-headache, spits blood, epistaxis, metrorrhagia, has blood in stool, puerperal blood faints.

The Rhizoma Pinelliae: source: be the tuber of the aroid Rhizoma Pinelliae.Chemical analysis: tuber is containing aminoacid, cupreol, choline, cupreol-β-D-Glucose glycosides, 3 such as volatile oil, a small amount of fat, starch, nicotine, phlegmatic temperament, aspartic acid, glutamic acid, arginine, beta-aminobutyric acids, 4-4-dihydroxy benzaldehyde, again containing the pharmacological action alkaloid similar to coniine and nicotine, the material of similar protoanemonin chafe.Tender shoots is containing 2,5-dihydroxy-.alpha.-toluic acid. and glycoside thereof.Nature and flavor: pungent, temperature, poisonous.Gui Jing: enter spleen, stomach warp.Function cures mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Control damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness.Outer subduing inflammation., vomiting regurgitation dizzy for abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, interior expectorant, breast gastral cavity painful abdominal mass are vexed, globus hystericus disease; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.

Rhizoma Tupistrae Chinensis: base is former: be the band tuber stem of the orchid family Herminium plant musk orchid.The property of medicine: < < Shanxi Chinese herbal medicine > >: " sweet in the mouth, warm in nature." function cures mainly: kidney and spleen invigorating, promoting blood flow to regulate menstruation, removing toxic substances.Cure mainly dizzy insomnia, early whitening of beard and hair, loss of appetite, menoxenia, venom.

Pericarpium Citri Reticulatae: base is former: this product is the dry mature skin of rutaceae orange and variety thereof.Nature and flavor: bitter, pungent, temperature.Gui Jing: return lung, spleen channel.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly: for fullness in the epigastrium and chest. lack of appetite and vomiting, cough with copious phlegm.

Rhizoma Dioscoreae: base is former: this product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Nature and flavor: sweet, flat.Gui Jing: return spleen, lung, kidney channel.Effect: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Cure mainly: for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.

Rhizoma Alismatis: base is former: this product is the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis.Chemical analysis: separate five kinds of triterpenoid compound in tuber: Alisol A, alisol B, acetic acid Alisol A ester, acetic acid alisol B ester and epialisol A; Another containing volatile oil (including furfural), a small amount of alkaloid, asparagine, a plant sterols, a kind of phytosterolin, fatty acid (Palmic acid, stearic acid, oleic acid, linoleic acid); Also resinous, protein and volume starch.Nature and flavor: sweet, cold.Gui Jing: return kidney, urinary bladder channel.Pharmacological action: 1. diuresis, the 2. impact on lipid metabolism.Effect: diuresis, clearing away damp-heat.Cure mainly: for dysuria. edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.

Indigo Naturalis: base is former: this product is the leaf of acanthaceous vegetable acanthaceous indigo, polygonaceae plant polygonum tinctorium ait. or cruciferae isatis or dried powder or the agglomerate that stem and leaf makes through processing.Character: this product is navy blue powder, and body is light, easily flies upward; Or be irregular porous agglomerate, with hand rubbing twist with the fingers smalls.Nature and flavor: salty, cold.Gui Jing: return Liver Channel.Effect: heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.Cure mainly: for maculae caused by violent heat pathogen, heat in blood is told nosebleed chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared.

Concha Ostreae: nature and flavor: salty, be slightly cold.Gui Jing: return liver, gallbladder, kidney channel.Concha Ostreae preparation method: clean, dry, pulverize use.Effect: suppressing the hyperactive liver and subsiding YANG; Tranquillization with heavy prescription; Hard masses softening and resolving; Restrain astringent or styptic treatment for spontaneous sweating.There is YIN nourishing, nourish blood, tonifying five ZANG-organs, invigorate blood circulation, fill the effects such as flesh.Cure mainly vertigo and tinnitus; Palpitation with fear insomnia; Scrofula goiter; Lump in the abdomen mass in the abdomen; Spontaneous sweating; Seminal emission; Metrorrhagia; Leukorrhagia.

Flos Carthami: base is former: this product is the dried floral of feverfew Flos Carthami.Character: this product is not for the tubular flower of ovary.Surface red is yellow or red.Tube is elongated, and tip 5 splits, and sliver is slat shape; Flower pesticide aggregates into tubular, yellow-white; Stigma elongated cylindrical, top differential fork.Matter is soft.Nature and flavor: pungent, temperature.Gui Jing: GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Cure mainly: for amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.

Herba Apocyni veneti: base is former: be the herb of apocynaceae plant Herba Apocyni veneti.Chemical analysis: root is containing cymarin, convallatoxigenin and K-strophanthus time glycoside-β.Leaf is containing globulariacitrin, catechin, anthraquinone, glutamic acid, alanine, valine, and potassium nitride etc., also containing Quercetin and Isoquercitrin.Herb is containing neoisorutin.Pharmacological action: 1. hypotensive effect; 2. cardiotonic.Nature and flavor: sweetness and bitterness, cool.Function cures mainly: relieves inflammation or internal heat, and blood pressure lowering, heart tonifying, diuresis.Control heart disease, hypertension, neurasthenia, hepatitis abdominal distention, nephritis edema.

Rhizoma Ligustici: base is former: this product is dry rhizome and the root of samphire Rhizoma Ligustici or Rhizoma Ligustici.Character: it is cylindrical that Rhizoma Ligustici rhizome is irregular nodular pattern, slightly distortion, has branch.Surface sepia or burgundy, coarse, there is vertical wrinkle, the circular stem foot of the residual several depressions of upside, downside has root trace and the undesirable root of most spot-like projections.Body is light, and matter is harder, frangibility, and section yellow or yellow-white, fibrous.Gas giving off a strong fragrance, acrid in the mouth, hardship, micro-fiber crops.River Rhizoma Ligustici is less, and rhizome is irregular lumps or column, has the root of most elongate curved.Nature and flavor: pungent, temperature.Gui Jing: return urinary bladder channel.Effect: dispel the wind, cold expelling, dehumidifying, pain relieving.Cure mainly: for anemofrigid cold, top, mountain peak pain, rheumatism podomere arthralgia pain.

Os Draconis: base is former: for ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc.Chemical analysis: be mainly calcium carbonate, calcium phosphate, still iron content, potassium, sodium, chlorine, sulfate radical etc.Nature and flavor: sweet puckery, flat.Gui Jing: GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, and spontaneous sweating, seminal emission stranguria with turbid discharge, tells nosebleed and has blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.

Radix Cynanchi Atrati: base is former: this product be Herba seu radix metaplexis rub section plant Radix Cynanchi Atrati or Cynanchum versicolor Bunge, dry root and rhizome.Chemical analysis: upright Radix Cynanchi Atrati root is containing cynanchol, volatile oil, cardiotonic glycoside.Nature and flavor: bitter, salty, cold.Gui Jing: return stomach, liver, kidney channel.Effect: clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.Cure mainly: for pathogenic warmth wound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood, pyretic stranguria.Stranguria with blood, swollen ulcer drug.

Radix Delphinii pogonanthi: base is former: for ranunculaceae plant must be spent the root of Herba delphinii grandiflori.Nature and flavor: pungent, cool.Function cures mainly: clearing away heat and expelling pathogen in the exterior, yang invigorating.Chemical analysis: must flower Herba delphinii grandiflori containing eldeline, it is bright for Herba delphinii grandiflori, methyllycaconitine, anthranoyl lycoctonine, septentrionaline, the bright alkali of Herba delphinii grandiflori color, core is for raw ketone, core is for raw, rocket larkspur is healthy and free from worry, also containing river, Yunnan delphinine A, B.Nature and flavor: pungent, cool; Gui Jing: return lung meridian.Function cures mainly: clearing away heat and expelling pathogen in the exterior; Yang invigorating.Main headache due to pathogenic wind-heat; Watery diarrhea

Folium Citri tangerinae: source: be the leaf of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae.Character: dried leaves multireel contracting, be Pedicellus et Pericarpium Trapae shape oblong or ellipse after open and flat, surperficial celadon or yellow green, smooth, can be according to seeing numerous transparent glandule points to light.Nature and flavor: toil, flat.Gui Jing: Zhu Zhenheng: " enter liver channel of foot-Jueyin edema caused by disorder of QI." function cures mainly: soothing the liver, circulation of qi promoting, reduces phlegm, detumescence poison.Control hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.

Radix Rehmanniae (Radix Rehmanniae): base is former: the fresh or dried root that this product is scrophulariaceae rehmannia glutinosa plant.Character: be irregular lumps or Long Circle, expand centre more, two ends are slightly thin, and what have is tiny, strip, slightly flat and distortion.Nature and flavor: sweet, cold.Gui Jing: GUIXIN, liver, kidney channel.Effect: clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.Cure mainly: for consumption of YIN caused by febrile disease, crimson tongue excessive thirst.Send out speckle dermexanthesis, spit blood, epistaxis.Laryngopharynx swelling and pain.Effect: clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and rugged blood, sends out speckle dermexanthesis.

Radix Cyathulae: base is former: this product is the dry root of amaranthaceous plant Radix Cyathulae.Character: this product is closely cylindrical, micro-distortion is thin or have a minority branch downwards slightly.Surface yellowish-brown or taupe, tool is indulged the hole skin of wrinkle, supporting root trace and most transverse projections.Nature and flavor: sweet, micro-hardship, flat.Gui Jing: return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Cure mainly: for amenorrhea carcinoma, retention of placenta, arthralgia, sufficient health clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.

Radix Scrophulariae: base is former: this product is the dry root of goatweed Radix Scrophulariae.Character: this product is class prop drawing shape, and centre is slightly thick or upper coarse and lower fine, some microbends.Surface lark or taupe, have irregular longitudinal furrow, the hole skin sample projection of growing crosswise and sparse transverse crack and a mark of fibrous root.Nature and flavor: sweet, bitter, salty, be slightly cold.Gui Jing: return lung, stomach, kidney channel.Effect: removing heat from blood YIN nourishing, eliminating fire and detoxication.Cure mainly: for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula is sick, diphtheria, carbuncle sore tumefacting virus.

Radix Ophiopogonis: base is former: this product is the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf).Character: this product is spindle, two ends are point slightly.Surface yellow-white or faint yellow, has thin longitudinal grin.Matter is pliable and tough, section yellow-white, and translucent, center pillar is tiny.Nature and flavor: sweet, micro-hardship, is slightly cold.Gui Jing: GUIXIN, lung, stomach warp.Function cures mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.

Marasmius equicrinis Muell.: base is former: Mycophyta Basidiomycetes Agaricales Agaricaceae Marasmius equicrinis Muell., is used as medicine with shoestring.Wei Bai mushroom section fungus Marasmius androsaceus (L.ex Fr.) Fr. rhzomorph.Chemical analysis: Marasmius androsaceus (L.ex Fr.) Fr. mycelia, contains mannitol, cholesteryl acetate, glycine in shoestring, aspartic acid, threonine, valines etc. are also isolated cupreol from mycelium, Palmic acid, 28 carbonic acid, p-hydroxycinnamic acid and tricin, separately containing humic acid.Nature and flavor: micro-hardship; Warm in nature.Gui Jing: return Liver Channel.Function cures mainly: the analgesic therapy of invigorating blood circulation.Main traumatic injury; Fracture pain; Migraine, various neuralgias, lumbago and skelalgia, rheumatic arthralgia.

SHANZHIZI: nature and flavor: hardship, cold.Gui Jing: GUIXIN, liver, lung, stomach warp.Chemical composition: containing flavonoid gardenin, pectin, tannin, crocin, crocetin, PEARLITOL 25C, nonacosane, cupreol.The another glycoside containing the smelly formaldehyde structure of multiple tool ring: gardenoside, geniposide pool element-1-glycoside, lattice Tegosept P-1-β-D-gentiobioside and shanzhiside in a small amount.Effect: calentura is vexed, liver-fire conjunctival congestion, headache, damp and hot yellow infantile malnutrition, stranguria, dysentery hematuria, aphtha of the mouth and tongue, sore swollen toxin, sprain and swell and ache.Heat clearing away, pathogenic fire purging, removing heat from blood.Cure mainly: calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, spits blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.

Fructus Aurantii: base is former: this product is the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.Nature and flavor: bitter, pungent, sour, temperature.Gui Jing: return spleen, stomach warp.Effect: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.Cure mainly: for the breast side of body stagnation of QI.Distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, uterine prolapse.The preparation method of Fructus Aurantii (parched): Fructus Aurantii is removed impurity.Clean, run through shave.After dry, sieve removes the broken flesh core falling.This product is wooden regular arcuation bar shaped thin slice.Tangent plane outer peel sepia is to brown, and mesocarp yellow-white is to yellowish-brown.Nearly outer rim You1-2Lie point-like grease chamber, inner side has a small amount of puce pulp.Stir-baked Fructus Aurantii in bran is got Fructus Aurantii sheet, according to parched with bran method, fries to complexion changed dark.This product is irregular arcuation bar shaped thin slice, and color is darker, and what have has a focal spot.

Radix Glycyrrhizae (Radix Glycyrrhizae): base is former: this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Nature and flavor: sweet, flat.Gui Jing: GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Radix Glycyrrhizae: Radix Glycyrrhizae is chosen to decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry.

Caulis Bambusae In Taenia: base is former: this product is the dry intermediate layer of the stem stalk of grass bambusa breviflora Munro, major part allusion quotation bamboo or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.Character: this product is curling agglomerating irregular strand or elongated laminar.Nature and flavor: sweet, be slightly cold.Gui Jing: attach to the lung and stomach meridians.Effect: removing heat-phlegm, relieves restlessness and prevents vomiting.Curing mainly: for phlegm-heat cough. gallbladder fire is held expectorant under the arm, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.

Chinese medicine composition prescription science provided by the invention, the preparation method of various dosage forms is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:

1,selected materials is all Chinese medicine material, without any side effects;

2,this prescription is by multiple Chinese herbal medicine synergy, and comprehensive measure makes the active ingredient rapid permeability focus of medicine, improves spleen, the heart, liver, kidney yin sun diagonosis of disorder, has regulated on the whole function of human body.

3,the present invention integrates the advantage of tcm therapy in hysteric conversion treatment and obtains, and has the advantages such as instant effect, short treating period, expense are little.

The specific embodiment

Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not limited to this.

embodiment 1alleviate hysteric conversion medicament, by following bulk drugs, be prepared from: Folium Nelumbinis 12g, Rhizoma Pinelliae 10g, Rhizoma Tupistrae Chinensis 6g, Pericarpium Citri Reticulatae 8g, Rhizoma Dioscoreae 30g, Rhizoma Alismatis 10g, Indigo Naturalis 25g, Os Draconis 3g, Concha Ostreae 22g, Flos Carthami 6g, Herba Apocyni veneti 6g, Rhizoma Ligustici 6g, Radix Cynanchi Atrati 9g, Radix Delphinii pogonanthi 6g, Folium Citri tangerinae 6g, Radix Rehmanniae 5g, Radix Cyathulae 9g, Radix Scrophulariae 6g, Radix Ophiopogonis 5g, Marasmius equicrinis Muell. 8g, SHANZHIZI 6g, Caulis Bambusae In Taenia 6g, Fructus Aurantii (parched) 5g, Radix Glycyrrhizae 3g.

The preparation method of above-mentioned alleviation hysteric conversion decoction:

(1) Indigo Naturalis, Os Draconis are pulverized, crossed 110 mesh sieves, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, add 30 ℃ of distilled water immersion 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, 110 ℃ of sterilizings 1 hour, cooling encapsulation, obtains.

The instructions of taking of decoction of the present invention: decoction is 7 days courses for the treatment of, takes twice (warm) every day, each 50m1-70m1.

embodiment 2the medicament of alleviating hysteric conversion, is prepared from by following bulk drugs: Folium Nelumbinis 20g, Rhizoma Pinelliae 14g, Rhizoma Tupistrae Chinensis 10g, Pericarpium Citri Reticulatae 12g, Rhizoma Dioscoreae 40g, Rhizoma Alismatis 18g, Indigo Naturalis 45g, Os Draconis 8g, Concha Ostreae 36g, Flos Carthami 12g, Herba Apocyni veneti 15g, Rhizoma Ligustici 15g, Radix Cynanchi Atrati 16g, Radix Delphinii pogonanthi 12g, Folium Citri tangerinae 15g, Radix Rehmanniae 12g, Radix Cyathulae 18g, Radix Scrophulariae 10g, Radix Ophiopogonis 9g, Marasmius equicrinis Muell. 16g, SHANZHIZI 15g, Caulis Bambusae In Taenia 12g, Fructus Aurantii (parched) 15g, Radix Glycyrrhizae 6g.

The preparation method of above-mentioned alleviation hysteric conversion decoction:

(1) Indigo Naturalis, Os Draconis are pulverized, crossed 160 mesh sieves, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, add 50 ℃ of distilled water immersion 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, 110 ℃ of sterilizings 4 hours, encapsulation, obtains.

The instructions of taking of decoction of the present invention: decoction is 7 days courses for the treatment of, takes twice (warm) every day, each 50m1-70m1.

Model case: patient, female, 32 years old, peasant is married.Main suit: stomach discomfort also feels to have gas migration under one's belt, more than belching of gas June, companion's anxiety, more than insomnia March.Patient Zeng Yin family's contradiction and household quarrel, and feel stomach discomfort for super thick, and with uncomfortable in chest, feel suffocated, abdominal distention, and " gas " migration under one's belt of thinking there is one,, there is thereafter the belching of gas in Chuan Zhi throat.Patient, when paresthesia epilepsy, was once hospitalized for treatment, and after infusing, having an injection, symptom takes a turn for the better.But quarrel again soon, patient's above-mentioned symptom shows effect again.On inspection: (1) patient's pathogenic process has clear and definite direct stimulation factor; (2) patient has clinical manifestation (3) patient's health check-up, the psychiatric system inspection of somatization to find no obviously corresponding organic disease; (4) patient has told that " gas " migration is in abdominal part and throat, belongs to the category of the traditional Chinese medical science " globus hystericus ".Be diagnosed as hysteric conversion.

Take the present embodiment gained and alleviate hysteric conversion decoction, take every day twice (warm), each 50m1-70m1,7 days courses for the treatment of.Take January, uncomfortable in chest, feel suffocated, abdominal distention is clearly better, and confusingly in the heart also alleviates, the amount of receiving increases, spirit can.Following the service is consolidated for 2 months, does not occur any discomfort when patient takes, and patient's self-induction symptom is eased.

embodiment 3the medicament of alleviating hysteric conversion, is prepared from by following bulk drugs: Folium Nelumbinis 14g, Rhizoma Pinelliae 11g, Rhizoma Tupistrae Chinensis 7g, Pericarpium Citri Reticulatae 9g, Rhizoma Dioscoreae 33g, Rhizoma Alismatis 12g, Indigo Naturalis 30g, Os Draconis 4g, Concha Ostreae 25g, Flos Carthami 8g, Herba Apocyni veneti 9g, Rhizoma Ligustici 9g, Radix Cynanchi Atrati 11g, Radix Delphinii pogonanthi 7g, Folium Citri tangerinae 8g, Radix Rehmanniae 7g, Radix Cyathulae 12g, Radix Scrophulariae 7g, Radix Ophiopogonis 6g, Marasmius equicrinis Muell. 10g, SHANZHIZI 9g, Caulis Bambusae In Taenia 8g, Fructus Aurantii (parched) 7g, Radix Glycyrrhizae 4g.

The preparation method of alleviating the agent of hysteric conversion thick paste is:

(1) Indigo Naturalis, Os Draconis are pulverized, sieved, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, adding distil water soaks 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add step (1) gained fine powder, mix, cooling, obtain thick paste agent.

The instructions of taking of thick paste agent of the present invention: get a soupspoon soft extract, be placed in cup, boiled water is taken after mixing it with water, a course for the treatment of of twice, 10 day every day.

embodiment 4the medicament of alleviating hysteric conversion, is prepared from by following bulk drugs: Folium Nelumbinis 18g, Rhizoma Pinelliae 13g, Rhizoma Tupistrae Chinensis 9g, Pericarpium Citri Reticulatae 11g, Rhizoma Dioscoreae 37g, Rhizoma Alismatis 16g, Indigo Naturalis 40g, Os Draconis 7g, Concha Ostreae 33g, Flos Carthami 10g, Herba Apocyni veneti 12g, Rhizoma Ligustici 12g, Radix Cynanchi Atrati 14g, Radix Delphinii pogonanthi 11g, Folium Citri tangerinae 13g, Radix Rehmanniae 10g, Radix Cyathulae 15g, Radix Scrophulariae 9g, Radix Ophiopogonis 8g, Marasmius equicrinis Muell. 14g, SHANZHIZI 12g, Caulis Bambusae In Taenia 10g, Fructus Aurantii (parched) 13g, Radix Glycyrrhizae 5g.

The preparation method of alleviating the thick paste agent of hysteric conversion is:

(1) Indigo Naturalis, Os Draconis are pulverized, sieved, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, adding distil water soaks 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add step (1) gained fine powder, mix, cooling, obtain thick paste agent.

The instructions of taking of thick paste agent of the present invention: get a soupspoon soft extract, be placed in cup, boiled water is taken after mixing it with water, a course for the treatment of of twice, 10 day every day.

Model case: patient, female, 17 years old, student.Main suit: patient is Students in grade one of senior middle school.In the time of at primary school, patient's school grade is excellent, and after junior middle school's second grade, patient's sensory learning is painstaking, and achievement glides, and abused by mother.Attend class and occur both hands shake occurring thereafter extremity shake while answering a question, whole body, tachypnea, under teacher's treatment, symptom is eased.But sense binocular blurring of vision, ears audition is fuzzy.Once suspended schooling January, after under father and mother's convincing by patient analysis, go to school again.After this, hear others say hands shake, numb and bring out, majority occurs in many occasions of people and can spontaneous remission.Father and mother are with it to hospital admission, are diagnosed as " hysteria ", after being hospitalized for treatment, and DeGrain.Find on inspection: patient's diminutive in stature, routine physical examination no abnormality seen.Interview: Consciousness, it is passive to contact.Binocular is stared a distant place, poker-faced, and binaural listening declines,, insight is substantially complete, and volitional behavior goes down; Blood, urine, just routine and biochemical analysis normal.Be diagnosed as hysteric conversion.

Take the present embodiment gained and alleviate the thick paste agent of hysteric conversion, adopt every day twice, get a soupspoon soft extract at every turn, be placed in cup, boiled water is taken after mixing it with water, 10 days courses for the treatment of.Treat three courses for the treatment of, symptom is improved, the reading of going to school, and school grade is on the lower side medium, underlying thought can be informed to mother.Following the service 1 month, patient's symptom is controlled, and patient is without any discomfort.

embodiment 5the medicament of alleviating hysteric conversion, is prepared from by following bulk drugs: Folium Nelumbinis 16g, Rhizoma Pinelliae 12g, Rhizoma Tupistrae Chinensis 8g, Pericarpium Citri Reticulatae 10g, Rhizoma Dioscoreae 35g, Rhizoma Alismatis 14g, Indigo Naturalis 35g, Os Draconis 5.5g, Concha Ostreae 29g, Flos Carthami 9g, Herba Apocyni veneti 10.5g, Rhizoma Ligustici 10.5g, Radix Cynanchi Atrati 12.5g, Radix Delphinii pogonanthi 9g, Folium Citri tangerinae 10.5g, Radix Rehmanniae 8.5g, Radix Cyathulae 13.5g, Radix Scrophulariae 8g, Radix Ophiopogonis 7g, Marasmius equicrinis Muell. 12g, SHANZHIZI 10.5g, Caulis Bambusae In Taenia 9g, Fructus Aurantii (parched) 10g, Radix Glycyrrhizae 4.5g.

The preparation method of alleviating hysteric conversion decoction is:

(1) Indigo Naturalis, Os Draconis are pulverized, crossed 140 mesh sieves, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, add 40 ℃ of distilled water immersion 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, 110 ℃ of sterilizings 2.5 hours, encapsulation, obtains.

The instructions of taking of decoction of the present invention: decoction is 7 days courses for the treatment of, takes twice (warm) every day, each 50m1-70m1.

test example 1for showing that medicament of the present invention, to alleviating the therapeutic effect of hysteric conversion, has carried out clinical observation to 230 routine cases, existing report is as follows:

1. data and method

1.1 physical data: diagnostic criteria: according to the diagnostic criteria of hysteric conversion: 1, have psychosocial factor as inducement.2, clinical manifestation is the de-mistake of sensation, tubular visual field, blind, aphonia, deafness, paralysis and tic etc.3, hinder social function.4, onset is anxious, and there is similar history of attack in the past.5. have fully according to getting rid of organic disease, patient is diagnosed, make a definite diagnosis patient's 230 examples of hysteric conversion, the age was at 16 to 35 years old.Be divided at random treatment group 130 examples (male 30 examples, female's 100 examples) and matched group 100 examples (male 45 examples, female's 55 examples).Two groups of patients learn processing by statistics at aspects such as sex, age, the course of disease, the state of an illness, and no statistical significance, has comparability.

1.2 Therapeutic Method: treatment group is taken the present embodiment 5 gained alleviation hysteric conversion decoctions, takes twice (warm) each 50m1-70m1,7 days courses for the treatment of every day.Matched group is taken other medicine (the conventional medicine such as citalopram, tiapride, paroxetine).Treat altogether 3 courses for the treatment of.

1.3 curative effect judging standards: effective: clinical symptoms is recovered normally substantially, can normally work, studying and living.Effective: clinical symptoms is clearly better or part recovers normal; Invalid: symptom is as front unchanged in treated.

Two groups of patient treatment results are relatively in Table 1.

Table 1 liang group patient curative effect comparison

Note: two groups of curative effect comparisons, difference has statistical significance (P < 0.01)

The present invention selects Os Draconis, Folium Nelumbinis, Indigo Naturalis, Folium Citri tangerinae etc. to carry out compatibility, makes after these drug regimens to produce synergism, can more effectively treat hysteropsychosis.In side the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae regulate the flow of vital energy strengthening the spleen, lung benefiting promotes the production of body fluid; Rhizoma Alismatis promoting diuresis to eliminate damp pathogen, clearing away damp-heat; Concha Ostreae, Radix Cynanchi Atrati, Radix Rehmanniae, heat clearing away tonifying YIN; Os Draconis tranquillizing the mind by relieving convulsion; Radix Cyathulae, Rhizoma Ligustici, Flos Carthami promoting blood circulation to remove blood stasis, wind-expelling pain-stopping.All medicines share, and invigorate blood circulation and can yin nourishing, and blood stasis dispelling and just not hindering, has one's ideas straightened out and the QI invigorating of holding concurrently, therefore can obtain good therapeutic effect.After patient takes three courses for the treatment of, total effective rate reaches 97.7%, and matched group is 73%, and treatment group is obviously better than matched group.

It should be pointed out that the specific embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or according to undoubted the obtaining of the written description of file, all should think the claimed scope of this patent.

Claims (10)

1. alleviate the medicament of hysteric conversion, it is characterized in that, by following bulk drugs, be prepared from, be weight portion: Folium Nelumbinis 12-20, Rhizoma Pinelliae 10-14, Rhizoma Tupistrae Chinensis 6-10, Pericarpium Citri Reticulatae 8-12, Rhizoma Dioscoreae 30-40, Rhizoma Alismatis 10-18, Indigo Naturalis 25-45, Os Draconis 3-8, Concha Ostreae 22-36, Flos Carthami 6-12, Herba Apocyni veneti 6-15, Rhizoma Ligustici 6-15, Radix Cynanchi Atrati 9-16, Radix Delphinii pogonanthi 6-12, Folium Citri tangerinae 6-15, Radix Rehmanniae 5-12, Radix Cyathulae 9-18, Radix Scrophulariae 6-10, Radix Ophiopogonis 5-9, Marasmius equicrinis Muell. 8-16, SHANZHIZI 6-15, Caulis Bambusae In Taenia 6-12, Fructus Aurantii (parched) 5-15, Radix Glycyrrhizae 3-6.

2. medicament as claimed in claim 1, is characterized in that, Folium Nelumbinis 14-18, Rhizoma Pinelliae 11-13, Rhizoma Tupistrae Chinensis 7-9, Pericarpium Citri Reticulatae 9-11, Rhizoma Dioscoreae 33-37, Rhizoma Alismatis 12-16, Indigo Naturalis 30-40, Os Draconis 4-7, Concha Ostreae 25-33, Flos Carthami 8-10, Herba Apocyni veneti 9-12, Rhizoma Ligustici 9-12, Radix Cynanchi Atrati 11-14, Radix Delphinii pogonanthi 7-11, Folium Citri tangerinae 8-13, Radix Rehmanniae 7-10, Radix Cyathulae 12-15, Radix Scrophulariae 7-9, Radix Ophiopogonis 6-8, Marasmius equicrinis Muell. 10-14, SHANZHIZI 9-12, Caulis Bambusae In Taenia 8-10, Fructus Aurantii (parched) 7-13, Radix Glycyrrhizae 4-5.

3. medicament as claimed in claim 1, is characterized in that, Folium Nelumbinis 16, the Rhizoma Pinelliae 12, Rhizoma Tupistrae Chinensis 8, Pericarpium Citri Reticulatae 10, Rhizoma Dioscoreae 35, Rhizoma Alismatis 14, Indigo Naturalis 35, Os Draconis 5.5, Concha Ostreae 29, Flos Carthami 9, Herba Apocyni veneti 10.5, Rhizoma Ligustici 10.5, Radix Cynanchi Atrati 12.5, Radix Delphinii pogonanthi 9, Folium Citri tangerinae 10.5, Radix Rehmanniae 8.5, Radix Cyathulae 13.5, Radix Scrophulariae 8, Radix Ophiopogonis 7, Marasmius equicrinis Muell. 12, SHANZHIZI 10.5, Caulis Bambusae In Taenia 9, Fructus Aurantii (parched) 10, Radix Glycyrrhizae 4.5.

4. the medicament as described in as arbitrary in claim 1-3, is characterized in that, this medicament is made to the preparation method of pharmaceutically acceptable decoction and thick paste agent.

5. medicament as claimed in claim 4, is characterized in that, the preparation method of described decoction is:

(1) Indigo Naturalis, Os Draconis are pulverized, sieved, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, adding distil water soaks 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, 110 ℃ of sterilizings, cooling encapsulation, obtains.

6. preparation method according to claim 5, is characterized in that, crosses 110-160 mesh sieve (the preferred 120-150 of mistake mesh sieve, was more preferably 140 mesh sieves) in step (1).

7. preparation method according to claim 5, is characterized in that, in step (2), the temperature of distilled water is 30-50 ℃ (preferably temperature is 35-45 ℃, and being more preferably temperature is 40 ℃).

8. preparation method according to claim 5, is characterized in that, in step (4), sterilization time is 1-4 hour (preferably sterilization time is 2-3 hour, and being more preferably sterilization time is 2.5 hours).

9. medicament as claimed in claim 4, is characterized in that, the preparation method of described thick paste agent is:

(1) Indigo Naturalis, Os Draconis are pulverized, sieved, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae and clean and be placed in pot, with slow fire, heat micro-stir-fry, then spray yellow wine, then fry to micro-dry, take out, dry levigation;

(3) Concha Ostreae is smashed to pieces, Radix Scrophulariae, yam slices, together be placed in crock with the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Herba Apocyni veneti, Radix Cynanchi Atrati, Radix Delphinii pogonanthi, Radix Rehmanniae, Radix Ophiopogonis, Marasmius equicrinis Muell., SHANZHIZI, Caulis Bambusae In Taenia, Fructus Aurantii (parched) and Radix Glycyrrhizae, adding distil water soaks 0.5-2 hour, then step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-3 hour, decoct for the second time 1-2 hour, decoct and finish to add for first 0.5 hour Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add step (1) gained fine powder, mix, cooling, obtain thick paste agent.

10. the application of the medicament as described in as arbitrary in claim 1-3 when the medicine of hysteric conversion is alleviated in preparation.