CN109350657A - A kind of composition that treating rheumatism, preparation method and applications - Google Patents
A kind of composition that treating rheumatism, preparation method and applications Download PDFInfo
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Abstract
The invention belongs to rheumatism treatment technical field of traditional Chinese medicines, a kind of composition for treating rheumatism is disclosed, is mainly prepared from the following materials: 8-12 parts of safflower, 13-17 parts of Radix Notoginseng, 10-14 parts of Rhizoma Et Radix Notopterygii, 10-14 parts of Radix Angelicae Pubescentis, 10-14 parts of Rhizoma Chuanxiong, 10-14 parts of teasel root, 10-14 parts of radix cyathulae, 13-17 parts of the root of Chinese clematis and 13-17 parts of leech.The invention also discloses the preparation method of the composition and purposes.The advantage of the invention is that, Radix Notoginseng swelling and pain relieving, safflower activating microcirculation and removing stasis medicinal is inducing meastruation to relieve menalgia, the dehumidifying cold dispelling of Rhizoma Et Radix Notopterygii Radix Angelicae Pubescentis, Rhizoma Chuanxiong blood-activating and qi-promoting, radix cyathulae promoting blood circulation benefit is got round by bribery, leech dispelling stasis of blood and stimulating the menstrual flow network, teasel root strengthening the bones and muscles enables the composition swelling and pain relieving, activating microcirculation and removing stasis medicinal, dehumidifying cold dispelling and benefit to get round by bribery by using the raw material of special ratios and type, preferably treat rheumatism or pre- antirheumatic exacerbation, caused pharmacological dependence or operative treatment after being in a bad way are avoided, mitigates patient suffering, and reduce medical burden for patient.
Description
Technical field
The invention belongs to rheumatism treatment technical field of traditional Chinese medicines, and in particular to a kind of composition for treating rheumatism, meanwhile,
The invention further relates to the preparation method and applications of the composition of the treatment rheumatism.
Background technique
Rheumatism refers to the main soft tissue for invading joint, muscle, bone and periarticular, such as tendon, ligament, synovial bursa or muscle
The disease at the positions such as film, wherein most is autoimmune disease.Rheumatic disease includes Diffuse Connective Tissue Disease (such as system
Property lupus erythematosus, dry syndrome, inflammatory myopathy, chorionitis, mixed connective tissue disease, Behcet's disease etc.), systemic vascular
Inflammation, SpA (such as ankylosing spondylitis, adjuvant arthritis, auspicious spy's syndrome), osteoarthritis and osteoporosis
Deng hundreds of to involve the disease general name based on the connective tissues such as bone, joint.
The complicated multiplicity of rheumatism, had not only intersected but also independent.In daily life, people inevitably contact cold water, humidity
Environment etc., it is for years, rheumatism is easily generated, causes the organs including joint impaired.When rheumatism invades human body
When not serious, people, which are typically chosen, does not treat or only does simple therapy, such as simple anti-inflammatory, and such mode cannot disappear completely
It, can only respite pain except Bones and joints surrounding soft tissue inflammation and intracorporal numbness poison.The patient of drug is used for a long time, to drug
Degree of dependence is increasing, and can only relieve pain, and cannot eradicate, and for more serious patient, can only use operative treatment,
But operative treatment rheumatism bone disease has greater risk, and can not resist wind, cold, wet, the evil secondary invasion to joint.Except upper
It states outside therapeutic modality, since rheumatism state of an illness early period is not serious, many people are limited to personal medical condition, and it is typically chosen and does not treat,
If things go on like this, only the state of an illness can be made more serious, the more money of later period investment and energy is caused to go treatment rheumatism.
Summary of the invention
In order to solve the above problems existing in the present technology, it is an object of that present invention to provide one kind without operation, avoids medicine
The composition for the treatment rheumatism that object relies on and therapeutic effect is good, while additionally providing the preparation method of the composition and its answering
With.
Inventor has found in long-term knowledge of TCM accumulation and rheumatism treatment practice, treats wind using following raw materials according
Diseases caused by dampness, it is significant in efficacy.It should be noted that the fine or not curative effect to the composition finally prepared of medicinal material is affected.
The raw materials used in the present invention is as follows:
Safflower, scientific name: Carthamus tinctorius L..Alias: red blue flower, thorn safflower, composite family, safflower plant,
Dry tubular flower, orange red, floral tube is narrow thin, and apex 5 is split, sliver narrow line shape, and anther yellow is unified into pipe, be higher by sliver it
Outside, there is column cap exposing in center.Have special fragrance, mildly bitter flavor.It is long with flower piece, color is scarlet, the soft person of matter is preferred.Main product Henan,
The ground such as Hunan, Sichuan, Xinjiang, Tibet.
[nature and flavor and channel tropism] is acrid in flavour and warm in nature.Converge to heart and liver channels.
[function and cure mainly] blood circulation, removing blood stasis and acesodyne.For menostasis, dysmenorrhea, lochia , abdominal mass and lump, the thoracic obstruction heart
Bitterly, stasis of blood, chest side of body twinge, injury from falling down, the swelling and pain of girdle ulcer.
[storage] is set at shady and cool drying, moisture-proof, mothproof.
[chemical component and effect] safflower is preceding including carthamin (carthamin) containing red and yellow pigment
Carthamin (precarthamin) is carthamin yellow (safflow yellow) A and B, the bright glucoside of safflower (safflominA) A, green
Ortho acid (chlorogenic acid) plus coffee are sour (caffeic acid), catechol (cate-chol), coke catechol
(pyrocatechol) and DOPA (dopa) etc..Modern medicine proves that safflower has certain effect to cardiovascular system tool, has
Inhibit key role, can increase coronary blood flow and cardiac muscle nutritional blood flow, it can be to resisting myocardial ischemia or myocardial infarction, it can be right
The effect of anti-a- adrenocepter and distend the blood vessels, and have weaker direct vasoconstriction effect.Meanwhile safflower can also drop
Low incidence of stroke and the death rate have protective effect to the brain tissue of chest infraction animal.Carthamin yellow in safflower is also
Have the function of blood coagulation resisting function, antifatigue, confrontation myocardial anoxia, in addition, also having certain analgesia, calmness and anti-inflammatory work
With.
Radix Notoginseng: for the dry root and rhizome of panax araliaceae plant Parmxnotoginseng (Burk.) F.H.Chen.Not
Claim pseudo-ginseng, Panax pseudoginseng, radix notoginseng or literary state Radix Notoginseng.Excavation before autumn, the flowers are in blossom, is cleaned, and separates main root, branch root and rhizome, is done
It is dry.Supporting root, which is practised, claims " rib ", and rhizome, which is practised, claims " clip ".Main root is in class cone or cylindrical, long 1~6cm, 1~4cm of diameter.
Surface taupe or lark have interrupted vertical wrinkle and supporting root trace.There is stem trace on top, around there is strumae.Weight, matter are hard
Real, section celadon, yellow green or canescence, woody part is micro- to be arranged radially.Gas is micro-, bitter Hui Tian.Rib it is cylindrical or
Cone, long 2~6cm, upper end diameter about 0.8cm, lower end diameter about 0.3cm.Clip in irregular shrinkage is blocky or strip,
There are several apparent stem traces and ring grain, section center celadon or white, edge bottle green or grey in surface.
[processing] Radix Notoginseng: taking crude drug, removes impurity, and the used time smashs to pieces.Radix Notoginseng powder: Radix Notoginseng, cleaning, drying, fine ground powder are taken.
Ripe Radix Notoginseng: taking net Radix Notoginseng to smash, and separates size block, with edible frying to surface brown color, takes out, leaches oil, finely ground powder.Radix Notoginseng
Piece: taking Radix Notoginseng, cleans, and steams thoroughly, takes out, is sliced in time, dry.
[nature and flavor and channel tropism] is sweet, bitter, temperature.Return liver, stomach meridian.
[function and cure mainly] dissipating stasis and stanching bleeding, detumescence ding-tong.For spitting blood, haematemesis, carp blood, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage,
Chest and abdomen shouting pain, tumbling and swelling.
[storage] is set at shady and cool drying, mothproof.
Rhizoma Et Radix Notopterygii: scientific name Notopterygium incisum Ting ex H.T.Chang, nickname Qiang is green, protects Qiang envoy, Hu
King envoy, Qiang is sliding, moves back wind envoy or black powder.It is Umbelliferae, Notopterygium herbaceos perennial, high up to 120 centimetres, rhizome is thick
Strong, stem is upright, cylindrical, band purple.Basal leaf and the lower portion of the stem leaf have handle, and blade three goes out formula three and returns pinnate compound leaf, and edge is incised
Shape is shallowly split to pinniform drastic crack;Leaf sheath film quality is grown and embraces stem.Universal umbel, side survivor Chang Buyu;Phyllary is linear, caducous;It is small
Phyllary is linear, spends majority, calyx tooth ovate triangle, petal white, oval to long round shape is oval, anther yellow, ellipse, flower
Base for post concora crush slightly swells.The mitogenetic long round shape of fruit, blooms July, 8-9 month result.
[processing] picks impurity, cleans, moisturizes, and is sliced, dries.
[pharmacological property] acrid flavour;It is bitter;It is warm-natured.Return bladder;Kidney channel.
[major function] dissipates exterior cold;Wind-damp dispelling;Sharp joint;Analgesic.Main affection of exogenous wind-cold;It is headache and adiapneustia;Mimeograph cold-dampness numbness;Wind
Water edema;Sore swollen toxin.
Radix Angelicae Pubescentis: for umbelliferae Angelica pubescens Angelica pubescens Maxim.f.biserrata
The dry root of Shanet Yuan.Excavation when seedling at the beginning of spring has just germinateed or autumn end cauline leaf is withered, removes fibrous root and silt, be dried to it is half-dried,
It banks up 2~3 days, is dried to again after feeling like jelly absolutely dry.Alias: Hu king envoy solely shakes careless, only cunning, houseleek, RADIX ANGELICAE PUBESCENTIS from Sichuan of China, meat Radix Angelicae Pubescentis, money
Go through Qiu's Radix Angelicae Pubescentis, the east of Sichuan Radix Angelicae Pubescentis, fragrant Radix Angelicae Pubescentis, achievement Radix Angelicae Pubescentis, big work, the big work in mountain or beautiful living.
[meridian distribution of property and flavor] is pungent, bitter, tepor.Return liver, kidney, bladder meridian.
[major function] expelling wind and eliminating dampness;Eliminating cold to stop pain.It is used for treating arthralgia due to cold and dampness;Lumbocrural pain;Few the moon volt wind headache, tooth of having a headache
Bitterly.
Have bitter scholar's Coumarins compound in [chemical component and effect] root, columbianetin (columbianetin) and
Its caproate (columbianetin acetate), osthole (osthol), different imperatorin
(isoimperatorin), bergapten (bergapten), xanthotoxin (xanthotoxin), columbianadin
(columbia-nadin), columbianetin glycoside (columbianetin- β-D-glcopy-ra-noside), hair is worked as
Return alcohol (anpubesol), angelol (angelol) D, G and B etc..Modern medicine proves that the alcohol extract (H6F4) in Radix Angelicae Pubescentis is to blood
Bolt is formed with inhibiting effect, and the methylene chloride of Radix Angelicae Pubescentis extracts part, and angiosthenia and heart contracting power can be made to increase, stimulation breathing, furthermore
Also there is spasmolysis, analgesia, calmness, anti-inflammatory and antibacterial action.
Rhizoma Chuanxiong: scientific name: Ligusticum chuanxiong hort, nickname mountain bring up poor, rhizome of chuanxiong Qiong, fragrant fruit, Hu Qiong, rhizome of chuanxiong Qiong,
Sparrow brain rhizome of chuanxiong or capital rhizome of chuanxiong.Cultivated plant, main product is in Sichuan, on Yunnan, Guizhou, Guangxi and other places, is grown on mild climatic environment.It is
A kind of Chinese medicinal plant is usually used in blood-activating and qi-promoting, and wind-expelling pain-stopping, Rhizoma Chuanxiong pungent-warm perfume (or spice) is dry, walks without keeping, and can go scattered, and uplink is reachable
Mountain peak top;Enter blood system again, downlink is up to the sea of blood.Promoting blood circulation effect is suitable for the various illnesss of stagnation of blood stasis extensively;Wind-expelling pain-stopping, effect
With favourable, the diseases such as cold and headache, rheumatic arthralgia can be controlled.It is the gas medicine in blood that former times people, which calls Rhizoma Chuanxiong, nearly says its pungent scattered, relieve stagnation of residing, leads to
The functions such as reach, relieve pain.
[meridian distribution of property and flavor] is acrid in flavour and warm in nature.Enter liver, gallbladder channel.
[major function] promote breath and open depression, it is wet to dispel wind-dryness, promoting blood circulation and stopping pain.It is dizzy to control air-cooled headache rotation, hypochondriac pain abdomen pain, arthritis muscle
Contraction, menostasis, difficult labour, postpartum stasis block pain, ulcer sores.For irregular menstruation, amenorrhea and algomenorrhea, lump in the abdomen abdominal pain, pricking pain in the chest falls and flutters
Swelling and pain, headache, rheumatic arthralgia.
(chuanxiongzine) containing ligustrazine, i.e. Tetramethylpyrazine (te- in [chemical component and effect] Rhizoma Chuanxiong
Tramethylpyrazine), loline or diindyl containing river (perlolyrine) i.e. 1- (5- methylol -2- furyl) -9h- pyrrole
Pyridine simultaneously [3,4-b] indoles [1- (5hydroxymethyl-2-furyl) -9H-pyrido [3,4-b] indole], Ligustilide
(ligustilide), Rhizoma Chuanxiong naphthalene furan lactone (wallichilide), 3- butylidenephthalide (3-butylideniphthalide),
3- butylidene -7- hydroxyl phthalide (3-butylidene-7-hydroxyphthalide), butylphthalide (butylphthalide)
Deng.Modern medicine proves that Rhizoma Chuanxiong Central nervous system has apparent sedation, heart rate can be made slack-off, while having antibacterial
And the effects of anti-radiation.
Teasel root: also known as shaven head, it is Dipsacaceae herbaceos perennial teasel
The dry root of DipsacusasperWall.exHenry is gained the name because of energy " continuous folding synthetism ".Autumn excavation, removes root head and palpus
Root, is dried to half-dried with small fire, when banking up " sweating " to inside virescence, then is dried." the southern regions of the Yunnan Province book on Chinese herbal medicine ": tonifying liver, strengthening the bones and muscles are fixed to pass through
Network, only pass through in (muscles and bones) ache, miscarriage prevention controls married woman leukorrhea, raw new blood, broken stasis of blood blood, falls stillborn foetus, and cough-relieving is coughed hemoptysis, control it is red it is white just
It is turbid.
[processing] teasel root piece is cleaned, and is moisturized, is cut sheet, dry.This product is in similar round or the sheet of ellipse.Exocuticle ash
Brown has vertical wrinkle to yellowish-brown.Section skin zone is blackish green or sepia, woody part lark or yellowish-brown, it is seen that radial arrangement
Vessel cluster line, there is a dark ring at forming layer position more.Gas is micro-, bitter, sweet tea and it is puckery.
[nature and flavor and channel tropism] hardship, pungent, tepor.Return liver and kidney channel.
[function and cure mainly] nourishing liver and kidney, strengthening the bones and muscles continue injured, only metrorrhagia and metrostaxis.For kidney deficiency and liver, soreness and weakness of waist and knees, rheumatism numbness
Bitterly, injury from falling down, injury of tendon and muscle fracture, metrorrhagia and metrostaxis, vaginal bleeding during pregnancy.Prepared RADIX DIPSACI with yellow rice wine is chiefly used in rheumatic arthralgia, injury from falling down, injury of tendon and muscle fracture.Prepared RADIX DIPSACI with salt solution
It is chiefly used in soreness and weakness of waist and knees.
[storage] sets dry place, mothproof.
[chemical component and effect] teasel root glucoside containing iridoid: sweroside (swero-side), vomiting nut glucoside
(loganin), cantleyoside (cantleyoside);Triterpenoid saponin;Akeboside D, that is, 3-O- α-L- arabopyranose base is normal
Spring rattan sapogenin -28-O- β-D- glucopyranosyl (1 → 6)-β-D- glucopyanoside etc..
Radix cyathulae: nickname berry-bearing campion root turns radix achyranthis bidentatae or beef cattle knee.For amaranthaceous plant radix cyathulae
The dry root of CyathulaofficinalisKuan.Autumn, the excavation of two season of winter, removing LU, fibrous root and silt are removed, dries or shine to half
It is dry, stack backwash.It dries or dries again.This product is slightly thin downwards or have a small number of branches in close cylindrical, micro- distortion, long by 30~
60cm, 0.5~3cm of diameter.Surface yellowish-brown or taupe, tool vertical wrinkle, supporting root trace and most horizontally long hole skin sample protrusions.Matter
It is tough, it is not easily broken, section is light yellow or brown color, and vascular bundle is dotted, is arranged in number wheel concentric rings.Gas is micro-, sweet.
[nature and flavor and channel tropism] is sweet, bitter, puts down.Return liver and kidney channel.
[function and cure mainly] dispelling stasis of blood and stimulating the menstrual flow, easing joint movement, inducing diuresis for treating strangurtia.For menostasis abnormal pigmentary deposit on the skin lump in the abdomen, placenta retension falls and flutters damage
Wound, rheumatic arthralgia, sufficient impotence muscle contraction, cards such as hematuria blood drenches.
The root of Chinese clematis: this product is ranunculaceae plant root of Chinese clematis ClematischinensisOsbeck, Clematis hexapetala
Or the drying root and rhizome of northeast clematis ClematismanshuricaRupr. ClematishexapetalaPall..Have
Dispelling wind and eliminating dampness, the effect of removing obstruction in channels to relieve pain.For rheumatic arthralgia, extremity numbness, muscle arteries and veins contraction, joint stuffiness, bone chokes with sobs the diseases such as larynx
Disease.Root of Chinese clematis rhizome is in the form of a column, long 1.5~10cm, 0.3~1.5cm of diameter;Surface light brown yellow;Top remains stem foot;Matter compared with
It is tough and tensile, section fibrous;Downside raw most radiculas.Root is in elongated cylindrical, slightly bent, long 7~15cm, and diameter 0.1~
0.3cm;Surface dark brown has thin longitudinal grin, and some skin zones fall off, and exposes yellow-white woody part;Matter is firmly crisp, frangibility, section skin zone
Relatively wide, woody part is faint yellow, is slightly square, and often has crack between skin zone and woody part.Gas is micro-, lightly seasoned.
[processing] removes impurity, cleans, moisturizes, dissection, dry.This product is in irregular section.Surface dark brown, sepia
Or brownish black, there is thin longitudinal grin, some skin zones fall off, and expose yellow-white woody part.Section skin zone is wider, and woody part is faint yellow, slightly in side
Shape or subcircular, often there is crack between skin zone and woody part.
[nature and flavor and channel tropism] is pungent, salty, temperature.Return bladder meridian.
[function and cure mainly] wind-damp dispelling, degrading the channel.For rheumatic arthralgia, extremity numbness, muscle arteries and veins contraction, joint stuffiness.
[storage] sets dry place.
Leech: alias leech also known as leech are that one kind is sucked blood annelid.Leech is in flat spindle, there is most links,
Long 4~10cm, wide 0.5~2cm.Back dark brown is dark brown, slightly swells, after water logging, it is seen that black splotch is lined up 5 and indulged
Line;The outside of belly is flat, brown color.Two sides brown color, front end is slightly sharp, and rear end blunt circle, both ends respectively have 1 sucker, and anterior sucker is not significant, after
Sucker is larger.Matter is crisp, frangibility, section colloidal substance.The micro- raw meat of gas.
[processing] leech is cleaned, dissection, dry.Boiling hot leech takes water purification leech section, is scalded with talcum powder to micro- and is heaved.This product is not in
The flat blocky or oblate cylindricality of rule, slightly heaves, surface brown color to dark brown, has a small amount of white talc powder.Section pine bubble, ash
White is to coke yellow.The micro- raw meat of gas.
[nature and flavor and channel tropism] is salty, bitter, puts down;It is slightly poisonous.Return liver warp.
[function and cure mainly] blood-breaking promoting menstruation, by stagnation resolvation disease.For blood stasis , abdominal mass and lump, hemiplegia falls and flutters damage
Wound.
[storage] sets dry place, mothproof.
Primary aqueous leech element (hirudin), is a kind of anticoagulant protein matter in [chemical component and effect] leech.Hiruto
Element, anticoagulating active is similar to hirudin, to inhibit fibrin ferment.Split fine enzyme, molecular weight 120,000, its fibrin degradation original
And fibrin, fracture wherein peptide bond, no longer with thrombin action and solidify, play anticoagulation.Cellosolve, anticoagulation
Similar to streptokinase, the activated fiber proteinogen front activating factor, is the activator of the fibrinolysin front activating factor.To can
Gloomy, on antagonism platelet membrane fibrinogen deceptor inhibits platelet aggregation.
Based on this, technical solution provided by the invention is as follows:
A kind of composition for treating rheumatism, is mainly prepared from the following materials: 8-12 parts of safflower, 13-17 parts of Radix Notoginseng,
10-14 parts of Rhizoma Et Radix Notopterygii, 10-14 parts of Radix Angelicae Pubescentis, 10-14 parts of Rhizoma Chuanxiong, 10-14 parts of teasel root, 10-14 parts of radix cyathulae, 13-17 parts of the root of Chinese clematis and
13-17 parts of leech.
Specifically, the composition, is mainly prepared from the following materials: 10 parts of safflower, 15 parts of Radix Notoginseng, 12 parts of Rhizoma Et Radix Notopterygii,
12 parts of Radix Angelicae Pubescentis, 12 parts of Rhizoma Chuanxiong, 12 parts of teasel root, 12 parts of radix cyathulae, 15 parts of the root of Chinese clematis and 15 parts of leech.
Specifically, the composition, the dosage form of the composition is vina.
A kind of aforementioned dosage form is the preparation method of the composition of vina, is included the following steps:
(1) it takes safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech to process respectively, obtains big gun
Safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech after system;
(2) safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech after processing are weighed according to quantity, are added
Enter carried out in white wine it is brewed, brew time be one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
Specifically, the preparation method, safflower after being processed in the step (2), Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root,
The ratio of the sum of weight of radix cyathulae, the root of Chinese clematis and leech and the weight of white wine is 28-38.5:1000.
A kind of application of aforementioned composition in preparation treatment shoulder neck rheumatism drug.
A kind of application of aforementioned composition in preparation treatment hand rheumatism drug.
A kind of application of aforementioned composition in preparation treatment leg rheumatism drug.
The invention has the benefit that
The composition for the treatment of rheumatism provided by the invention, Radix Notoginseng swelling and pain relieving, safflower activating microcirculation and removing stasis medicinal is inducing meastruation to relieve menalgia, Rhizoma Et Radix Notopterygii
Radix Angelicae Pubescentis dehumidifying cold dispelling, Rhizoma Chuanxiong blood-activating and qi-promoting, radix cyathulae promoting blood circulation benefit are got round by bribery, and leech dispelling stasis of blood and stimulating the menstrual flow network, teasel root strengthening the bones and muscles is led to
The raw material using special ratios and type to be crossed, enables the composition swelling and pain relieving, activating microcirculation and removing stasis medicinal, dehumidify cold dispelling, and benefit is got round by bribery,
Rheumatism or pre- antirheumatic exacerbation are preferably treated, caused pharmacological dependence or operative treatment after being in a bad way is avoided, subtracts
Light patient suffering, and medical burden is reduced for patient.
Specific embodiment
Further explaination is done to the present invention combined with specific embodiments below.
Embodiment 1:
The purpose of the present embodiment is that providing a kind of composition for treating rheumatism, preparation method is as follows:
(1) take authentic medicinal herbs safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech respectively by
Processed according to the concocting method of aforementioned every medicinal material, safflower after being processed, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae,
The root of Chinese clematis and leech;
(2) safflower 8g, Radix Notoginseng 13g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Rhizoma Chuanxiong 10g, teasel root 10g, river ox after processing are weighed according to quantity
Knee 10g, root of Chinese clematis 13g and leech 13g are added in 3-4kg white wine brewed one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
Embodiment 2:
The purpose of the present embodiment is that providing a kind of composition for treating rheumatism, preparation method is as follows:
(1) take authentic medicinal herbs safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech respectively by
Processed according to the concocting method of aforementioned every medicinal material, safflower after being processed, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae,
The root of Chinese clematis and leech;
(2) safflower 10g, Radix Notoginseng 15g, Rhizoma Et Radix Notopterygii 12g, Radix Angelicae Pubescentis 12g, Rhizoma Chuanxiong 12g, teasel root 12g, river ox after processing are weighed according to quantity
Knee 12g, root of Chinese clematis 15g and leech 15g are added in 3-4kg white wine brewed one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
Embodiment 3:
The purpose of the present embodiment is that providing a kind of composition for treating rheumatism, preparation method is as follows:
(1) take authentic medicinal herbs safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech respectively by
Processed according to the concocting method of aforementioned every medicinal material, safflower after being processed, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae,
The root of Chinese clematis and leech;
(2) safflower 12g, Radix Notoginseng 17g, Rhizoma Et Radix Notopterygii 14g, Radix Angelicae Pubescentis 14g, Rhizoma Chuanxiong 14g, teasel root 14g, river ox after processing are weighed according to quantity
Knee 14g, root of Chinese clematis 17g and leech 17g are added in 3-4kg white wine brewed one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
Embodiment 4:
The purpose of the present embodiment is that providing a kind of composition for treating rheumatism, preparation method is as follows:
(1) take authentic medicinal herbs safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech respectively by
Processed according to the concocting method of aforementioned every medicinal material, safflower after being processed, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae,
The root of Chinese clematis and leech;
(2) safflower 14g, Radix Notoginseng 17g, Rhizoma Et Radix Notopterygii 14g, Radix Angelicae Pubescentis 10g, Rhizoma Chuanxiong 14g, teasel root 14g, river ox after processing are weighed according to quantity
Knee 10g, root of Chinese clematis 13g and leech 17g are added in 3-4kg white wine brewed one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
Embodiment 5:
The purpose of the present embodiment is that providing a kind of composition for treating rheumatism, preparation method is as follows:
(1) take authentic medicinal herbs safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech respectively by
Processed according to the concocting method of aforementioned every medicinal material, safflower after being processed, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae,
The root of Chinese clematis and leech;
(2) safflower 10g, Radix Notoginseng 13g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 14g, Rhizoma Chuanxiong 14g, teasel root 14g, river ox after processing are weighed according to quantity
Knee 14g, root of Chinese clematis 15g and leech 15g are added in 3-4kg white wine brewed one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
Embodiment 6:
The purpose of the present embodiment is that providing a kind of composition for treating rheumatism, preparation method is as follows:
(1) take authentic medicinal herbs safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech respectively by
Processed according to the concocting method of aforementioned every medicinal material, safflower after being processed, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae,
The root of Chinese clematis and leech;
(2) safflower 12g, Radix Notoginseng 15g, Rhizoma Et Radix Notopterygii 12g, Radix Angelicae Pubescentis 14g, Rhizoma Chuanxiong 12g, teasel root 12g, river ox after processing are weighed according to quantity
Knee 14g, root of Chinese clematis 13g and leech 17g are added in 3-4kg white wine brewed one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
Because prohibiting for pregnant woman containing safflower and Radix Notoginseng etc. in the composition for the treatment rheumatism that the embodiment of the present invention 1 to 6 provides
With.
The effect of each medicinal material is as follows in the composition for the treatment of rheumatism provided by the invention:
Safflower blood circulation removing blood stasis and acesodyne, Radix Notoginseng dissipating stasis and stanching bleeding detumescence ding-tong, Rhizoma Et Radix Notopterygii dissipate exterior cold, wind-damp dispelling, sharp joint, stop
Bitterly;Radix Angelicae Pubescentis expelling wind and eliminating dampness, eliminating cold to stop pain;Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping;Teasel root nourishing liver and kidney, continuous injured, is only collapsed at strengthening the bones and muscles
Leakage;Radix cyathulae dispelling stasis of blood and stimulating the menstrual flow, easing joint movement, inducing diuresis for treating strangurtia;Root of Chinese clematis dispelling wind and eliminating dampness is removed obstruction in channels to relieve pain;Leech blood-breaking promoting menstruation, by the stasis of blood
Eliminating mass, expelling wind and clearing away cold can be relieved affected part pain after getting through rheumatism siltation blocking.
Effect example 1
One patient, female, 33 years old.Cervical spondylosis is broken out suddenly, and both hands arm cannot be raised upwards.Head cannot be low or backward downwards
It faces upward, it can not normal activity.When medical, entire shoulder neck position skin temperature is lower, and when treatment uses aforementioned therapies rheumatism daily
Composition (liquid medicine) massages affected part, and the time is up to 1 hour, and dosage is about 50g liquid medicine, and massage is primary daily, continues
After one week treatment can move freely shoulder neck.
Effect example 2
One patient, female, 58 years old.Suffer from rheumatism at finger-joint, seriously affects normal life.When medical, redness and swelling of joints is for example red
Radish is unable to water breakthrough, can not grasp thing, steeps affected part with the composition (liquid medicine) of aforementioned therapies rheumatism daily, is aided with when necessary
Massage, once a day, not red pneumonedema after one month can normal activity.
Effect example 3
One patient, female, 70 years old.Both legs pain cannot land, and seriously affect normal life.Treatment is primary daily, uses every time
The composition (liquid medicine) of aforementioned therapies rheumatism massages affected part, can walk below after two months.
Effect example 4
One patient, male, 64 years old.Hemiplegia, carpus is ice-cold, and upper and lower limbs can not normal stretching and beading.Aforementioned therapies are used daily
The composition (liquid medicine) of rheumatism steeps affected part, and is aided with massage, once a day.Crutch walking can be aided with after one month.
Effect example 5
One patient, male, 45 years old, sciatica can not sit chill stool.The composition of aforementioned therapies rheumatism is used daily
(liquid medicine) massages affected part, once a day, normal sitting after two weeks.
The composition for the treatment of rheumatism provided by the invention can also treat the rheumatism at various other positions, be limited to a piece
Width, this will not be repeated here.
The present invention is not limited to above-mentioned optional embodiment, anyone can show that other are each under the inspiration of the present invention
The product of kind form.Above-mentioned specific embodiment should not be understood the limitation of pairs of protection scope of the present invention, protection of the invention
Range should be subject to be defined in claims, and specification can be used for interpreting the claims.
Claims (8)
1. a kind of composition for treating rheumatism, which is characterized in that be mainly prepared from the following materials: 8-12 parts of safflower, three
Seven 13-17 parts, 10-14 parts of Rhizoma Et Radix Notopterygii, 10-14 parts of Radix Angelicae Pubescentis, 10-14 parts of Rhizoma Chuanxiong, 10-14 parts of teasel root, 10-14 parts of radix cyathulae, Wheeling
Celestial 13-17 parts and leech 13-17 parts.
2. composition according to claim 1, which is characterized in that be mainly prepared from the following materials: 10 parts of safflower, three
7 15 parts, 12 parts of Rhizoma Et Radix Notopterygii, 12 parts of Radix Angelicae Pubescentis, 12 parts of Rhizoma Chuanxiong, 12 parts of teasel root, 12 parts of radix cyathulae, 15 parts of the root of Chinese clematis and 15 parts of leech.
3. composition according to claim 1 or 2, it is characterised in that: the dosage form of the composition is vina.
4. a kind of preparation method of composition as claimed in claim 3, which comprises the steps of:
(1) safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech is taken to process respectively, after obtaining processing
Safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech;
(2) safflower, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, radix cyathulae, the root of Chinese clematis and leech after processing are weighed according to quantity, are added white
Carried out in wine it is brewed, brew time be one month or more;
(3) take supernatant to get the composition of the treatment rheumatism.
5. the preparation method according to claim 4, it is characterised in that: safflower, Radix Notoginseng, Qiang after being processed in the step (2)
Work, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, teasel root, the sum of the weight of radix cyathulae, the root of Chinese clematis and leech and the ratio of the weight of white wine are 28-38.5:
1000。
6. a kind of application of the composition described in claim 1-3 any one in preparation treatment shoulder neck rheumatism drug.
7. a kind of application of the composition described in claim 1-3 any one in preparation treatment hand rheumatism drug.
8. a kind of application of the composition described in claim 1-3 any one in preparation treatment leg rheumatism drug.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110812456A (en) * | 2019-11-18 | 2020-02-21 | 广州玉婷阁医药科技有限公司 | Traditional Chinese medicine composition for bathing |
CN111700961A (en) * | 2020-06-04 | 2020-09-25 | 刘关良 | Medicine for treating rheumatic ostealgia |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1562265A (en) * | 2004-04-11 | 2005-01-12 | 王双凯 | Medicinal liquor for trating rheumatism |
CN103041223A (en) * | 2012-12-23 | 2013-04-17 | 徐化利 | Traditional Chinese medicine formula for treating rheumatic arthritis |
CN104383434A (en) * | 2014-11-03 | 2015-03-04 | 刘兆云 | Externally applied medicament for treating traumatic injuries and rheumatism and preparation method of externally applied medicament |
CN104758382A (en) * | 2014-04-15 | 2015-07-08 | 河南中医学院 | Traditional Chinese medicine composition, ointment for treating rheumatism and preparation method thereof |
CN105012720A (en) * | 2015-08-28 | 2015-11-04 | 李金玉 | Traditional Chinese medicine composition for treating osteopathy |
CN106138276A (en) * | 2016-08-19 | 2016-11-23 | 林力 | Promoting blood circulation to restore menstrual flow network bone strengthening Traditional Chinese medicine for steeping foot formula |
CN106822272A (en) * | 2017-03-28 | 2017-06-13 | 南阳金丰元易医药科技有限公司 | A kind of plaster |
-
2018
- 2018-12-10 CN CN201811504901.9A patent/CN109350657A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1562265A (en) * | 2004-04-11 | 2005-01-12 | 王双凯 | Medicinal liquor for trating rheumatism |
CN103041223A (en) * | 2012-12-23 | 2013-04-17 | 徐化利 | Traditional Chinese medicine formula for treating rheumatic arthritis |
CN104758382A (en) * | 2014-04-15 | 2015-07-08 | 河南中医学院 | Traditional Chinese medicine composition, ointment for treating rheumatism and preparation method thereof |
CN104383434A (en) * | 2014-11-03 | 2015-03-04 | 刘兆云 | Externally applied medicament for treating traumatic injuries and rheumatism and preparation method of externally applied medicament |
CN105012720A (en) * | 2015-08-28 | 2015-11-04 | 李金玉 | Traditional Chinese medicine composition for treating osteopathy |
CN106138276A (en) * | 2016-08-19 | 2016-11-23 | 林力 | Promoting blood circulation to restore menstrual flow network bone strengthening Traditional Chinese medicine for steeping foot formula |
CN106822272A (en) * | 2017-03-28 | 2017-06-13 | 南阳金丰元易医药科技有限公司 | A kind of plaster |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110812456A (en) * | 2019-11-18 | 2020-02-21 | 广州玉婷阁医药科技有限公司 | Traditional Chinese medicine composition for bathing |
CN111700961A (en) * | 2020-06-04 | 2020-09-25 | 刘关良 | Medicine for treating rheumatic ostealgia |
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