CN104189491A - Medicament for relieving hysterical psychological disorders and preparation method of medicament - Google Patents

Abstract

The invention discloses a medicament for relieving hysterical psychological disorders. The medicament is prepared from the following raw medicinal materials in parts by weight: 3 to 6 parts of borax, 8 to 18 parts of ruddle, 12 to 18 parts of white baneberry, 12 to 20 parts of lotus leaves, 10 to 14 parts of pinellia ternate, 8 to 12 parts of pericarpium citri reticulatae, 30 to 40 parts of Chinese yam, 22 to 36 parts of concha ostreae, 25 to 45 parts of amber, 8 to 16 parts of marasmius androsaceus, 6 to 12 parts of safflower carthamus, 6 to 15 parts of Chinese ligusticum rhizome, 3 to 8 parts of cinnabar, 9 to 15 parts of apocynum venetum, 6 to 15 parts of tangerine leaves, 5 to 12 parts of radix rehmanniae, 8 to 16 parts of radix paeoniae alba, 6 to 15 parts of herminium monorhis(L.)R.Br., 9 to 18 parts of medicinal cyathula root, 10 to 18 parts of rhizoma alismatis, 25 to 45 parts of indigo naturalis and 3 to 8 parts of ossa draconis. The medicament has the beneficial effects that the selected materials are all traditional Chinese medicine materials, so that the medicament has no toxic or side effect; the formula of the medicament completely conforms to the principles of traditional Chinese medicine science and the physical and mental characteristics of patients with the hysterical psychological disorders, so that different formulas with different functions can be formed according to different people on the premise of the general principles; and the medicament is low in medicinal material cost because material sources are easily available, so that the burdens of the patients are reduced.

Description

Alleviate medicament and the preparation method of hysteropsychosis

Technical field

The present invention relates to Chinese medicine field, particularly relate to a kind of medicament and preparation method of alleviating hysteropsychosis.

Background technology

Hysteropsychosis, claims again divergence type obstacle.System is due to obvious psychological factor, and as life events, intrapsychic conflict or strong emotional experience, imply to wait to cause.Clinical main manifestations mental symptom is main, has Emotional outburst, and acute onset under Nervous and Mental Factors effect shows as and cries, laughs at, rolls about, shouts etc.Emotion changes rapidly, often with the action of drama sample expression.Can also be the dysfunction of body, can find motion, sensation, reflection and vegetative nerve functional disturbance.But corresponding device matter basis is not found in detailed inspection, do not meet the physiological characteristics of neuro anatomy yet.Hysteropsychosis is often caused the obstacle of sensation aspect by obvious direct stimulation and bad hint, have lasting Negative Emotional to experience and stress when patient shows effect, and psychological anxiety level is raise.Patient, after being upset, presents disturbance of consciousness and disorder of affect in various degree, and patient's emotion color is dense, exaggeration, affected and be subject to hint.Common manifestation has convulsion, limb tremor, paralyses, stands up and can not, not say disease and aphonia, hyperesthesia, decreased sensation or disappearance with walking, globus hystericus and special sense pipe obstacle, as hysterical deafness, blind and hysterical vomiting, singultus, the autonomic nerve function obstacles such as Hyperventilation.

Original annotation of hysteria one word is " regard disease also ", also referred to as hysteria, is a kind of more common neuropathy, common with rural area.The clinical manifestation of hysteropsychosis: 1. haziness, can range symptom in fancy.2. Emotional outburst; 3. forget; 4. the attached body of supernatural, multiple personality.This class symptom is without the basis of organic lesion, and it can, because hint produces, also can change or disappear because of hint.The Therapeutic Principle of hysteropsychosis: 1. away from Psychological stimulation source; 2. explain supportive psychotherapy; 3. hint and hypnotherapy; 4. medicine control excitement is restless.Clinical treatment method has psychotherapy to comprise expressivetherapy, suggestive treatment, hypnotherapy at present, Drug therapy, and naturopathy comprises Chinese medicine, acusector or acupuncture etc.The rule for the treatment of can be improved patient's emotion, alleviates patient's body sense of discomfort.Form of Chinese drug, is that master develops into sheet, cream, ball, electuary, aerosol and injection from decoction, particularly alleviates the expansion blood vessel Chinese medicine of hysteropsychosis, has greatly improved the clinical value for the treatment of by Chinese herbs hysteropsychosis.

Publication number CN 101062257A(application number 200710011348.0) Chinese patent literature disclose one and treated top, mad, sudden and violent psychotic medicine, this medicine is by 40 grams of Concha Ostreaes, 35 grams of Os Draconis, 30 grams, Poria, 6 grams, Cinnabaris, 15 grams of Bulbus Liliies, 15 grams of Cortex Albiziaes, 15 grams of the Radix Paeoniae Albas, 20 grams of Radix Glycyrrhizae Preparatas, 20 grams of Pericarpium Citri Reticulataes, 20 grams of Rhizoma Cyperis, 20 grams, the Radix Rehmanniae, 25 grams of compositions of the Radix Aucklandiae.Publication No. CN 103127444 A(application numbers 201110378888.9) Chinese patent literature disclose one and treated the psychotic Chinese medicine of type of stagnation of phlegm and QI; it is to be made up of the proportioning of following medical material weight portion: Semen Ziziphi Spinosae 18-2 part; Caulis Akebiae 6-8 part; Radix Curcumae 9-11 part, Folium Bambusae 11-15 part, Radix Polygalae 6-8 part; Radix Et Rhizoma Rhei 13-17 part; Lignum Aquilariae Resinatum 2-4 part, Radix Glycyrrhizae 4-6 part, Radix Paeoniae Alba 11-15 part; Radix Bupleuri 9-11 part; Rhizoma Coptidis 4-6 part, Radix Gentianae 9-11 part, Radix Ophiopogonis 12-14 part; Calculus Bovis 1.8-2.2 part; Rhizoma Acori Graminei 8-10 part, Moschus 0.18-0.2 part, Poria cum Radix Pini 15-19 part.Publication number CN 102988873 A(application numbers 201210573960.8) Chinese patent literature a kind of Chinese medicine composition for the treatment of yang deficiency of spleen and stomache mental disorder is disclosed, made by the each raw material of following weight portion: Radix Glycyrrhizae 5-1 part, Fructus Amomi 5-15 part, Pericarpium Citri Reticulatae 8-20 part, Radix Astragali 8-20 part, Radix Codonopsis 8-20 part, Cortex Cinnamomi 8-20 part, Radix Aconiti Lateralis Preparata 8-20 part, Rhizoma Curculiginis 8-20 part, Herba Epimedii 8-20 part, Radix Morindae Officinalis 8-20 part, Carapax et Plastrum Testudinis 10-20 part, Radix Rehmanniae Preparata 10-20 part.

In a word, there is no at present the specific medicament for the treatment of hysteropsychosis, mainly adopt symptomatic treatment.Hysteria patient is usually with symptom and physical discomforts such as anxiety, depression, encephalasthenia, pain, insomnias.These symptoms often lure the self suggestion basis that patient shows effect into, use relative medicine control symptom very necessary.Drug therapy need be carried out choose reasonable for symptom.Chinese medicine is being obtained good curative effect in treatment aspect primary disease, but also has some problems: not ideal enough to the treatment of disease due to treatment factor clinically, the research of polygenic inheritance is had much room for improvement, and avoid the generation of associated diseases for genetic reasons.

Summary of the invention

For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, easy medicament of the alleviation hysteropsychosis of clothes and preparation method thereof for a long time.This curative effect of medicine is definite and have no side effect.

Technical scheme of the present invention is:

The medicament of alleviating hysteropsychosis, is prepared from by following bulk drugs, is weight portion: Borax 3-6, Haematitum 8-18, Radix Delphinii pogonanthi 12-18, Folium Nelumbinis 12-20, Rhizoma Pinelliae 10-14, Pericarpium Citri Reticulatae 8-12, Rhizoma Dioscoreae 30-40, Concha Ostreae 22-36, succinum 25-45, Marasmius equicrinis Muell. 8-16, Flos Carthami 6-12, Rhizoma Ligustici 6-15, Cinnabaris 3-8, Herba Apocyni veneti 9-15, Folium Citri tangerinae 6-15, Radix Rehmanniae 5-12, Radix Paeoniae Alba 8-16, Rhizoma Tupistrae Chinensis 6-15, Radix Cyathulae 9-18, Rhizoma Alismatis 10-18, Indigo Naturalis 25-45, Os Draconis 3-8.

In preferred scheme, Borax 4-5, Haematitum 11-15, Radix Delphinii pogonanthi 14-16, Folium Nelumbinis 14-18, Rhizoma Pinelliae 11-13, Pericarpium Citri Reticulatae 9-11, Rhizoma Dioscoreae 33-37, Concha Ostreae 26-32, succinum 30-40, Marasmius equicrinis Muell. 10-14, Flos Carthami 8-10, Rhizoma Ligustici 9-12, Cinnabaris 4-7, Herba Apocyni veneti 10-14, Folium Citri tangerinae 9-12, Radix Rehmanniae 7-10, Radix Paeoniae Alba 10-14, Rhizoma Tupistrae Chinensis 8-13, Radix Cyathulae 11-16, Rhizoma Alismatis 12-16, Indigo Naturalis 30-40, Os Draconis 4-7.

Be more preferably Borax 4.5, Haematitum 13, Radix Delphinii pogonanthi 15, Folium Nelumbinis 16, the Rhizoma Pinelliae 12, Pericarpium Citri Reticulatae 10, Rhizoma Dioscoreae 35, Concha Ostreae 29, succinum 35, Marasmius equicrinis Muell. 12, Flos Carthami 9, Rhizoma Ligustici 10.5, Cinnabaris 6.5, Herba Apocyni veneti 12, Folium Citri tangerinae 10.5, Radix Rehmanniae 8.5, the Radix Paeoniae Alba 12, Rhizoma Tupistrae Chinensis 10.5, Radix Cyathulae 13.5, Rhizoma Alismatis 14, Indigo Naturalis 35, Os Draconis 5.5.

The present invention also provides the preparation method of aforementioned medicament being made to pharmaceutically acceptable decoction, pill and thick paste agent.

The preparation method of described decoction is:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 120-180 mesh sieve, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, and is together placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, adds clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decocts for the first time 2-4 hour, decocts for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, sterile packaged, to obtain final product.

The preparation method of the decoction of hysteropsychosis is alleviated in above-mentioned alleviation, and preferred scheme is in step (1), to cross 140-160 mesh sieve (preferred mistake 150 mesh sieves).

The preparation method of the decoction of hysteropsychosis is alleviated in above-mentioned alleviation, and preferred scheme is that the temperature that adds clear water in step (2) is 25-45 DEG C (preferably temperature is 30-40 DEG C, and being more preferably temperature is 35 DEG C).

The preparation method of described pill is:

(1) each crude drug was pulverized to 120-160 mesh sieve (preferably 130-150 mesh sieve), obtained fine powder;

(2) refined honey: honey is placed in to evaporating dish and is heated to boil, continue to refine into refined honey degree, drag for floating foam band glossy;

(3) Mel of having refined is mixed in proportion to (ratio of medicated powder and refined honey is by weight being 1:1.5) with step (1) gained fine powder, make pill according to the preparation for processing of pill.

The preparation method of described thick paste agent is:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 120-180 mesh sieve, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, and is together placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, adds clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decocts for the first time 2-4 hour, decocts for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add step (1) gained fine powder, mix, cooling, obtain thick paste agent.

The application of medicament described in the present invention also provides in the time that the medicine of hysteropsychosis is alleviated in preparation.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Haematitum: base is former: be the Ore of oxide-based mineral bloodstone.Chemical analysis: main containing iron sesquioxide, wherein ferrum 70%, oxygen 30%, sometimes impure titanium, magnesium, aluminum, silicon and moisture.Nature and flavor: bitter, sweet, flat.Gui Jing: return liver, stomach, heart born of the same parents warp.Function cures mainly: suppressing the hyperactive liver town is contrary, cooling blood for hemostasis.Control eructation vomiting, dysphagia and regurgitation, asthma, infantile convulsion, spits blood, epistaxis, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, bleeding not during menses.

Folium Nelumbinis: base is former: the dried leaves that this product is nymphaeaceae plant lotus.Chemical analysis: leaf is containing nuciferine, nuciferine, miltanthin, armepavine, pronuciferine (+)-Pronuciferine, N-demethyl nuciferine, D-N-methyl coclaurine, anonaine, liriodendrin, Quercetin, Isoquercitrin, lotus glycoside, tartaric acid, citric acid, malic acid, gluconic acid, oxalic acid, succinic acid, tannin.Also contain the alkaline components of resisting mitosis effect.Nature and flavor: hardship, flat.Gui Jing: return liver, spleen, stomach warp.Effect: clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.Cure mainly: for multiple hemorrhage and puerperal blood faints.

The Rhizoma Pinelliae: base is former: this product is the dry tuber of the aroid Rhizoma Pinelliae.Chemical analysis: tuber is containing aminoacid, cupreol, choline, cupreol-β-D-Glucose glycosides, 3 such as volatile oil, a small amount of fat, starch, nicotine, phlegmatic temperament, aspartic acid, glutamic acid, arginine, beta-aminobutyric acids, 4-4-dihydroxy benzaldehyde, again containing the pharmacological action alkaloid similar to coniine and nicotine, the material of similar protoanemonin chafe.Tender shoots is containing 2,5-dihydroxy-.alpha.-toluic acid. and glycoside thereof.Nature and flavor: pungent, warm; Poisonous; Gui Jing: return spleen, stomach, lung meridian.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Cure mainly: for abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache, vomiting regurgitation, thymus painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.

Pericarpium Citri Reticulatae: base is former: this product is the dry mature skin of rutaceae orange and variety thereof.Nature and flavor: bitter, pungent, temperature.Gui Jing: return lung, spleen channel.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly: for fullness in the epigastrium and chest. lack of appetite and vomiting, cough with copious phlegm.

Concha Ostreae (Concha Ostreae): nature and flavor: salty, be slightly cold.Gui Jing: return liver, gallbladder, kidney channel.Concha Ostreae preparation method: clean, dry, pulverize use.Effect: suppressing the hyperactive liver and subsiding YANG; Tranquillization with heavy prescription; Hard masses softening and resolving; Restrain astringent or styptic treatment for spontaneous sweating.There is YIN nourishing, nourish blood, tonifying five ZANG-organs, invigorate blood circulation, fill the effects such as flesh.Cure mainly vertigo and tinnitus; Palpitation with fear insomnia; Scrofula goiter; Lump in the abdomen mass in the abdomen; Spontaneous sweating; Seminal emission; Metrorrhagia; Leukorrhagia.

Marasmius equicrinis Muell.: medical material Ji Yuan: Mycophyta Basidiomycetes Agaricales Agaricaceae Marasmius equicrinis Muell., is used as medicine with shoestring.For Bai Mo section fungus Marasmius androsaceus (L.ex Fr.) Fr. rhzomorph.Chemical analysis: Marasmius androsaceus (L.ex Fr.) Fr. mycelia, contains mannitol, cholesteryl acetate, glycine in shoestring, aspartic acid, threonine, valines etc. are also isolated cupreol from mycelium, Palmic acid, 28 carbonic acid, p-hydroxycinnamic acid and tricin, separately containing humic acid.Nature and flavor: micro-hardship; Warm in nature.Gui Jing: return Liver Channel.Function cures mainly: the analgesic therapy of invigorating blood circulation.Main traumatic injury; Fracture pain; Migraine, various neuralgias, lumbago and skelalgia, rheumatic arthralgia.

Flos Carthami: base is former: this product is the dried floral of feverfew Flos Carthami.Character: this product is not to be with the tubular flower of ovary.Surface red is yellow or red.Tube is elongated, and tip 5 splits, and sliver is slat shape; Flower pesticide aggregates into tubular, yellow-white; Stigma elongated cylindrical, top differential fork.Matter softness.Nature and flavor: pungent, temperature.Gui Jing: GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Cure mainly: for amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.

Rhizoma Ligustici: base is former: this product is dry rhizome and the root of samphire Rhizoma Ligustici or Rhizoma Ligustici.Character: it is cylindrical that Rhizoma Ligustici rhizome is irregular nodular pattern, slightly distortion, has branch.Surface sepia or burgundy, coarse, there is vertical wrinkle, the circular stem foot of the residual several depressions of upside, downside has root trace and the undesirable root of most spot-like projections.Body is light, and matter is harder, frangibility, and section yellow or yellow-white, fibrous.Gas giving off a strong fragrance, acrid in the mouth, hardship, micro-fiber crops.River Rhizoma Ligustici is less, and rhizome is irregular lumps or column, has the root of most elongate curved.Nature and flavor: pungent, temperature.Gui Jing: return urinary bladder channel.Effect: dispel the wind, cold expelling, dehumidifying, pain relieving.Cure mainly: for anemofrigid cold, top, mountain peak pain, rheumatism podomere arthralgia pain.

Herba Apocyni veneti: base is former: be the herb of apocynaceae plant Herba Apocyni veneti.Chemical analysis: root is containing cymarin, convallatoxigenin and K-strophanthus time glycoside-β.Leaf is containing globulariacitrin, catechin, anthraquinone, glutamic acid, alanine, valine, and potassium nitride etc., also containing Quercetin and Isoquercitrin.Herb is containing neoisorutin.Pharmacological action: 1. hypotensive effect; 2. cardiotonic.Nature and flavor: sweetness and bitterness, cool.Function cures mainly: relieves inflammation or internal heat, and blood pressure lowering, heart tonifying, diuresis.Control heart disease, hypertension, neurasthenia, hepatitis abdominal distention, nephritis edema.

Folium Citri tangerinae: base is former: be the leaf of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae.Character: dried leaves multireel contracting, be Pedicellus et Pericarpium Trapae shape oblong or ellipse after open and flat, surperficial celadon or yellow green, smooth, can be according to seeing numerous transparent glandule points to light.Nature and flavor: toil, flat.Gui Jing: Zhu Zhenheng: " enter liver channel of foot-Jueyin edema caused by disorder of QI." function cures mainly: soothing the liver, circulation of qi promoting, reduces phlegm, detumescence poison.Control hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.

The Radix Paeoniae Alba: base is former: this product is the dry root of ranunculaceae plant Radix Paeoniae.Chemical analysis: root is containing paeoniflorin, paeonol, paeoniflorin, benzoic acid approximately 1.07%, volatile oil, fatty oil, resin, tannin, sugar, starch, phlegmatic temperament, protein, cupreol and triterpenes.Another Sichuan product person, containing a kind of acidic materials, has inhibitory action to staphylococcus aureus.Nature and flavor: bitter, sour, be slightly cold.Gui Jing: return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Cure mainly: dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.

Rhizoma Tupistrae Chinensis: base is former: be the band tuber stem of the orchid family Herminium plant musk orchid.The property of medicine: " Shanxi Chinese herbal medicine ": " sweet in the mouth, warm in nature." function cures mainly: kidney and spleen invigorating, promoting blood flow to regulate menstruation, removing toxic substances.Cure mainly dizzy insomnia, early whitening of beard and hair, loss of appetite, menoxenia, venom.

Radix Cyathulae: base is former: this product is the dry root of amaranthaceous plant Radix Cyathulae.Character: this product is closely cylindrical, micro-distortion is thin or have a minority branch downwards slightly.Surface yellowish-brown or taupe, tool is indulged the hole skin of wrinkle, supporting root trace and most transverse projections.Nature and flavor: sweet, micro-hardship, flat.Gui Jing: return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Cure mainly: for amenorrhea carcinoma, retention of placenta, arthralgia, sufficient health clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.

Rhizoma Alismatis: base is former: this product is the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis.Chemical analysis: separate five kinds of triterpenoid compound in tuber: Alisol A, alisol B, acetic acid Alisol A ester, acetic acid alisol B ester and epialisol A; Another containing volatile oil (including furfural), a small amount of alkaloid, asparagine, a plant sterols, a kind of phytosterolin, fatty acid (Palmic acid, stearic acid, oleic acid, linoleic acid); Also resinous, protein and volume starch.Nature and flavor: sweet, cold.Gui Jing: return kidney, urinary bladder channel.Pharmacological action: 1. diuresis, the 2. impact on lipid metabolism.Effect: diuresis, clearing away damp-heat.Cure mainly: for dysuria. edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.

Indigo Naturalis: base is former: this product is the leaf of acanthaceous vegetable acanthaceous indigo, polygonaceae plant polygonum tinctorium ait. or cruciferae isatis or dried powder or the agglomerate that stem and leaf makes through processing.Character: this product is navy blue powder, and body is light, easily flies upward; Or be irregular porous agglomerate, with hand rubbing twist with the fingers smalls.Nature and flavor: salty, cold.Gui Jing: return Liver Channel.Effect: heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.Cure mainly: for maculae caused by violent heat pathogen, heat in blood is told nosebleed chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared.

Os Draconis: base is former: for ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc.Chemical analysis: be mainly calcium carbonate, calcium phosphate, still iron content, potassium, sodium, chlorine, sulfate radical etc.Nature and flavor: sweet puckery, flat.Gui Jing: GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, and spontaneous sweating, seminal emission stranguria with turbid discharge, tells nosebleed and has blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.

Radix Delphinii pogonanthi: base is former: for ranunculaceae plant must be spent the root of Herba delphinii grandiflori.Nature and flavor: pungent, cool.Function cures mainly: clearing away heat and expelling pathogen in the exterior, yang invigorating.Chemical analysis: must flower Herba delphinii grandiflori containing eldeline, it is bright for Herba delphinii grandiflori, methyllycaconitine, anthranoyl lycoctonine, septentrionaline, the bright alkali of Herba delphinii grandiflori color, core is for raw ketone, core is for raw, rocket larkspur is healthy and free from worry, also containing river, Yunnan delphinine A, B.Nature and flavor: pungent; Cool.Gui Jing: lung meridian.Function cures mainly: clearing away heat and expelling pathogen in the exterior; Yang invigorating.Main headache due to pathogenic wind-heat; Watery diarrhea

Borax: base is former: for mineral Borax is through the refining crystallization forming.Chemical analysis: be sodium tetraborate.Character: this product is colourless translucent crystallization or white crystalline powder; Odorless; There are air slaking; Aqueous solution shows alkaline reaction.This product is easily molten in boiling water or glycerol, in water, dissolves, insoluble in ethanol.Nature and flavor: Gan Xian is cool.Gui Jing: enter lung, stomach warp.Function cures mainly: heat clearing away expectorant, detoxify anticorrosion.Control laryngopharynx swelling and pain, aphtha of the mouth and tongue, conjunctival congestion cataracta, bone is choked, dysphagic, and cough expectorant is thick.

Rhizoma Dioscoreae: base is former: this product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Nature and flavor: sweet, flat.Gui Jing: return spleen, lung, kidney channel.Effect: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Cure mainly: for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.

Succinum: base is former: the prolonged Hydrocarbon that condenses and form under the resin burial ground for pinaceae plant in ancient times.Chemical analysis: main resinous, volatile oil.In addition, contain succooxyabietic acid, succinoabietinolic acid, succinosilvic acid, succinoresinol, succinoabietol and succinic acid etc.Nature and flavor: sweet, flat.Gui Jing: enter the heart, liver, small intestine meridian.Function cures mainly: tranquillizing the mind by relieving convulsion, dissipating blood stasis hemostasis, relieving stranguria by diuresis.Control infantile convulsion epilepsy, palpitation with fear insomnia, stranguria with blood hematuria, urinary obstruction, women's amenorrhea, stops the stasis of blood stomachache puerperal, skin sore, traumatic injuries.

Cinnabaris: base is former: this product is sulfide-based mineral cinnabar family cinnabar, main Containing Sulfur hydrargyrum.Character: this product is granular or block aggregation, is graininess or piece lamellar.Cerise or kermesinus, streak redness is to maroon, tool gloss.Nature and flavor: sweet, be slightly cold; Poisonous.Gui Jing: GUIXIN warp.Effect: clear away heart-fire relieving convulsion, the removing toxic substances of calming the nerves.Cure mainly: for palpitation and being susceptible to fright, insomnia and dreamful sleep, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.

Radix Rehmanniae: base is former: the fresh or dried root that this product is scrophulariaceae rehmannia glutinosa plant.Radix Rehmanniae: be irregular lumps or Long Circle, expand centre more, two ends are slightly thin, and what have is tiny, strip, slightly flat and distortion.Nature and flavor: Radix Rehmanniae is sweet, bitter, cold.Radix Rehmanniae: nature and flavor: sweet, cold.Gui Jing: GUIXIN, liver, kidney channel.Effect: Radix Rehmanniae clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.Cure mainly: for consumption of YIN caused by febrile disease, crimson tongue excessive thirst.Send out speckle dermexanthesis, spit blood, epistaxis.Laryngopharynx swelling and pain.Radix Rehmanniae: effect: clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and rugged blood, sends out speckle dermexanthesis.

Drug prescription science provided by the invention, the preparation method of various dosage forms is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:

1,selected materials is all Chinese medicine material, without any side effects;

2,this prescription meets Chinese medicine principle and hysteropsychosis patient body and mind feature completely, under the prerequisite of general principle, can have different prescriptions according to different crowd, function difference.

3,medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.

embodiment 1the medicament of alleviating hysteropsychosis, is prepared from by following bulk drugs: Borax 3g, Haematitum 8g, Radix Delphinii pogonanthi 12g, Folium Nelumbinis 12g, Rhizoma Pinelliae 10g, Pericarpium Citri Reticulatae 8g, Rhizoma Dioscoreae 30g, Concha Ostreae 22g, succinum 25g, Marasmius equicrinis Muell. 8g, Flos Carthami 6g, Rhizoma Ligustici 6g, Cinnabaris 3g, Herba Apocyni veneti 9g, Folium Citri tangerinae 6g, Radix Rehmanniae 5g, Radix Paeoniae Alba 8g, Rhizoma Tupistrae Chinensis 6g, Radix Cyathulae 9g, Rhizoma Alismatis 10g, Indigo Naturalis 25g, Os Draconis 3g.

The preparation method of the decoction of above-mentioned alleviation hysteropsychosis:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 120 mesh sieves, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, together be placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, add 25 DEG C of clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-4 hour, decoct for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, sterile packaged, to obtain final product.

The instructions of taking of decoction of the present invention: decoction is 10 days courses for the treatment of, takes twice (warm) every day, each 40m1-60m1.

embodiment 2the medicament of alleviating hysteropsychosis, is prepared from by following bulk drugs: Borax 6g, Haematitum 18g, Radix Delphinii pogonanthi 18g, Folium Nelumbinis 20g, Rhizoma Pinelliae 14g, Pericarpium Citri Reticulatae 12g, Rhizoma Dioscoreae 40g, Concha Ostreae 36g, succinum 45g, Marasmius equicrinis Muell. 16g, Flos Carthami 12g, Rhizoma Ligustici 15g, Cinnabaris 8g, Herba Apocyni veneti 15g, Folium Citri tangerinae 15g, Radix Rehmanniae 12g, Radix Paeoniae Alba 16g, Rhizoma Tupistrae Chinensis 15g, Radix Cyathulae 18g, Rhizoma Alismatis 18g, Indigo Naturalis 45g, Os Draconis 8g.

The preparation method of alleviating the decoction of hysteropsychosis is:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 180 mesh sieves, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, together be placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, add 45 DEG C of clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-4 hour, decoct for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, sterile packaged, to obtain final product.

The instructions of taking of decoction of the present invention: decoction is 10 days courses for the treatment of, takes twice (warm) every day, each 40m1-60m1.

Model case: king xx, man, 23 years old, people from Fuyang.One's parents are both dead since the childhood, brought up by uncle, introverted.Love for many years with girl friend, two people often quarrel, and have one day two people because trival matters break out again after fierce quarrel, and Wang runs away from home, and three day time has been gone near two small towns Fuyang.Later can not recall completely leaving process.Again there is migration because thing and household conflict afterwards, utilize automobile, train etc. to go to the ground such as Xuzhou.Detained and notify household to take back by local Public Security Organs afterwards.Check and find: patient's narrowing of conscious span, look natural, binocular is stared, emotional responses is coordinated, can not know memory for the process of going out, without insight, body and neurologic check are all without extremely, electroencephalogram is normal.Be diagnosed as hysteropsychosis.

Take the present embodiment gained and alleviate the decoction of hysteropsychosis, take every day twice (warm), each 40m1-60m1,10 days courses for the treatment of.Take two courses for the treatment of, symptom is dramatical change, as awakens from the dream, and symptom in disease is had to part memory, but detail memory is unclear.There is not any discomfort to consolidate curative effect in following the service 2 courses for the treatment of, patient's self-induction symptom is controlled when patient takes.

embodiment 3the medicament of alleviating hysteropsychosis, is prepared from by following bulk drugs: Borax 4g, Haematitum 11g, Radix Delphinii pogonanthi 14g, Folium Nelumbinis 14g, Rhizoma Pinelliae 11g, Pericarpium Citri Reticulatae 9g, Rhizoma Dioscoreae 33g, Concha Ostreae 26g, succinum 30g, Marasmius equicrinis Muell. 10g, Flos Carthami 8g, Rhizoma Ligustici 9g, Cinnabaris 4g, Herba Apocyni veneti 10g, Folium Citri tangerinae 9g, Radix Rehmanniae 7g, Radix Paeoniae Alba 10g, Rhizoma Tupistrae Chinensis 8g, Radix Cyathulae 11g, Rhizoma Alismatis 12g, Indigo Naturalis 30g, Os Draconis 4g.

The preparation method of alleviating the pill of hysteropsychosis is:

(1) each crude drug was pulverized to preferably 150 mesh sieves, obtained fine powder;

(2) refined honey: Mel is placed in to evaporating dish and is heated to boil, continue to refine into refined honey degree, drag for floating foam band glossy;

(3) Mel of having refined is mixed in proportion to (ratio of medicated powder and refined honey is by weight being 1:1.5) with step (1) gained fine powder, make pill according to the preparation for processing of pill.

The using method of pill of the present invention is: adopt every day three times, and each 1-2 ball (approximately 0.6 gram/ball of drug loading), with warm water delivery service, 10 days courses for the treatment of.

Model case: all xx, female, private owner.In October, 2010, Mrs Zhou, in the way of going home, suffers unidentified personnel's kidnapping, extorts.After household pays, muffled eyes night by offender and throw away in wilderness.Saved by household.Henceforth, patient occurs that consciousness is in a trance, often feels that someone will injure oneself.Start from one's dream at night, make a scene.The dressing of Dou Yaoqiao on the daytime village is gone out under friend's relatives company., often in frightened state, even there is suicidal tendency in rear aggravation.Tranquilizer can only respite, and conditions of patients is more serious later.Find on inspection: patient under normal condition with ordinary person without two, body and neurologic check are all without extremely.Be diagnosed as hysteropsychosis.

Take the present embodiment gained and alleviate the pill of hysteropsychosis, adopt every day three times, each 1-2 ball, with warm water delivery service, 10 days courses for the treatment of.Take after two courses for the treatment of, patient's mental status has clear improvement, and phobia also alleviates, and continues to take two courses for the treatment of, and the every symptom of patient is all effectively alleviated, and fear disappears, the peace of sleeping night, patient's suitable symptom invariably after taking medicine.

embodiment 4the medicament of alleviating hysteropsychosis, is prepared from by following bulk drugs: Borax 5g, Haematitum 15g, Radix Delphinii pogonanthi 16g, Folium Nelumbinis 18g, Rhizoma Pinelliae 13g, Pericarpium Citri Reticulatae 11g, Rhizoma Dioscoreae 37g, Concha Ostreae 32g, succinum 40g, Marasmius equicrinis Muell. 14g, Flos Carthami 10g, Rhizoma Ligustici 12g, Cinnabaris 7g, Herba Apocyni veneti 14g, Folium Citri tangerinae 12g, Radix Rehmanniae 10g, Radix Paeoniae Alba 14g, Rhizoma Tupistrae Chinensis 13g, Radix Cyathulae 16g, Rhizoma Alismatis 16g, Indigo Naturalis 40g, Os Draconis 7g.

The preparation method of alleviating the thick paste agent of hysteropsychosis is:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 120-180 mesh sieve, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, and is together placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, adds clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decocts for the first time 2-4 hour, decocts for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add step (1) gained fine powder, mix, cooling, obtain thick paste agent.

The instructions of taking of thick paste agent of the present invention: get a soupspoon soft extract, be placed in cup, boiled water is taken after mixing it with water, a course for the treatment of of twice, 10 day every day.

Model case: Lee, female, 27 years old, company clerk.In classmate's party, under classmate's instigating, Lee and several schoolgirl are played the game of " pen is celestial ", Lee plays for the first time, inquire about very intensively the emotional problem of oneself, while having played one many hours, one of them schoolgirl is told everybody, if to 12 celestial also non-stop words of pen, he is exactly the health of having gone up someone.At this moment Lee is ceaselessly calling her with regard to the sound of repeatedly hearing the man who oneself is in unrequited love with always, and represents the love to her, and she also " sees " this person really earnestly.Now her both hands are put into the appearance of pen, gyrate on overhead, and classmate has seen, embraces her both hands, and her head makees pen and rotating, and her head and hands are embraced, her foot, rotating, cannot stop, and say that pen is celestial to cry oneself uncontrollable must living.Within second day, she is brought to hospital's Psychology Dept., while requiring her hands motionless when doctor checks, from the moving foot-propelled of wardrobe, hear with see all relevant with pen celestial being.Haziness shape, insight is poor, thinks oneself to be exactly that pen is celestial, can predict following many things.Interview: mind is dim, when expression and flat, time and exciting easy on the trigger, behavior restlessness, often rotate health and both hands, posture is strange, sometimes speakes to oneself, sometimes shout, there are auditory hallucination and photis, the boy that undue pursuit is admired, vain hope is seeks from " pen is celestial ".Without insight.Anencephaly organic disease.Be diagnosed as hysteropsychosis according to above performance.

Take the present embodiment gained and alleviate the thick paste agent of hysteropsychosis, while taking, get a soupspoon soft extract, be placed in cup, boiled water is taken after mixing it with water, a course for the treatment of of twice, 10 day every day.Take one month, patient is conscious, is emotionally stable, and sickness rate reduces, and when morbidity, symptom obviously alleviates, and takes again 1 month, and patient shows effect once in a while during this time, and when outbreak, emotion can be controlled, Consciousness, and insight strengthens, and stable disease can be controlled.Following the service 3 months, patient's symptom is alleviated greatly, can orthobiosis and work.

embodiment 5the medicament of alleviating hysteropsychosis, is prepared from by following bulk drugs: Borax 4.5, Haematitum 13, Radix Delphinii pogonanthi 15, Folium Nelumbinis 16, the Rhizoma Pinelliae 12, Pericarpium Citri Reticulatae 10, Rhizoma Dioscoreae 35, Concha Ostreae 29, succinum 35, Marasmius equicrinis Muell. 12, Flos Carthami 9, Rhizoma Ligustici 10.5, Cinnabaris 6.5, Herba Apocyni veneti 12, Folium Citri tangerinae 10.5, Radix Rehmanniae 8.5, the Radix Paeoniae Alba 12, Rhizoma Tupistrae Chinensis 10.5, Radix Cyathulae 13.5, Rhizoma Alismatis 14, Indigo Naturalis 35, Os Draconis 5.5.

The preparation method of alleviating the decoction of hysteropsychosis is:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 150 mesh sieves, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, together be placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, add 35 DEG C of clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decoct for the first time 2-4 hour, decoct for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, sterile packaged, to obtain final product.

The instructions of taking of decoction of the present invention: decoction is 10 days courses for the treatment of, takes twice (warm) every day, each 40m1-60m1.

Test example 1 is for showing that medicament of the present invention, to alleviating the therapeutic effect of hysteropsychosis, has carried out clinical observation to 237 routine cases, and existing report is as follows:

1. data and method

1.1 physical data: 1, selection standard: be foundation according to Chinese Spirit classification of diseases and diagnostic criteria and the diagnostic criteria of neurosis clinical position, in March, 2010-2013 year June, choose 237 examples in four hospitals and be diagnosed as hysteropsychosis Disease.Wherein male 52 examples, female's 185 examples, the age is 17-36 year, course of disease average out to 2.5 years.2, cardinal symptom distributes: (1) emotional lability: 135 examples such as excited, restless, irritability and the Chinese musical telling of paroxysmal forced smile; (2) behavior disorder: impulsion, refusing to eat, run, 42 examples such as self inflicted injury; (3) killedly exaggerate, envy, the attached body of supernatural, 32 examples such as multiple personality; (4) hallucination, forget, 28 examples such as sleep disorder, silence.3, grouping: all patients are divided into treatment group 146 examples (male 26 examples, female's 120 examples) and matched group 91 examples (male 26 examples, female's 65 examples) at random.Two groups of patients learn processing by statistics at aspects such as sex, age, the course of disease, the state of an illness, and no statistical significance, has comparability.

1.2 Therapeutic Method: treatment group is taken the present embodiment 5 gained alleviation hysteropsychosis decoctions, takes twice (warm) each 40m1-60m1,10 days courses for the treatment of every day.Matched group is taken other medicine (the conventional medicine such as sulpiride, Risperidal, perphenazine).Treat altogether 3 courses for the treatment of.

1.3 curative effect judging standards: effective: clinical symptoms is recovered normally substantially, can normally work, studying and living.Effective: clinical symptoms is clearly better or part recovers normal; Invalid: symptom is as front unchanged in treated.

Two groups of patient treatment results are relatively in table 1.

Table 1 liang group patient curative effect comparison

The present invention selects Borax, Rhizoma Ligustici, Indigo Naturalis, Os Draconis etc. to carry out compatibility, makes after these drug regimens to produce synergism, can more effectively treat hysteropsychosis.In side the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae regulate the flow of vital energy strengthening the spleen, lung benefiting promotes the production of body fluid; Rhizoma Alismatis promoting diuresis to eliminate damp pathogen, clearing away damp-heat; Concha Ostreae, the Radix Paeoniae Alba, Radix Rehmanniae, heat clearing away tonifying YIN; Os Draconis tranquillizing the mind by relieving convulsion; Radix Cyathulae, Rhizoma Ligustici, Flos Carthami promoting blood circulation to remove blood stasis, wind-expelling pain-stopping.All medicines share, and invigorate blood circulation and can yin nourishing, and blood stasis dispelling and just not hindering, has one's ideas straightened out and the QI invigorating of holding concurrently, therefore can obtain good therapeutic effect.After patient takes three courses for the treatment of, total effective rate reaches 97.3%, and matched group is 73%, and treatment group is obviously better than matched group.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or according to undoubted the obtaining of the written description of file, all should think the claimed scope of this patent.

Claims (10)

1. the medicament of alleviating hysteropsychosis, is characterized in that, is prepared from by following bulk drugs, is weight portion: Borax 3-6, Haematitum 8-18, Radix Delphinii pogonanthi 12-18, Folium Nelumbinis 12-20, Rhizoma Pinelliae 10-14, Pericarpium Citri Reticulatae 8-12, Rhizoma Dioscoreae 30-40, Concha Ostreae 22-36, succinum 25-45, Marasmius equicrinis Muell. 8-16, Flos Carthami 6-12, Rhizoma Ligustici 6-15, Cinnabaris 3-8, Herba Apocyni veneti 9-15, Folium Citri tangerinae 6-15, Radix Rehmanniae 5-12, Radix Paeoniae Alba 8-16, Rhizoma Tupistrae Chinensis 6-15, Radix Cyathulae 9-18, Rhizoma Alismatis 10-18, Indigo Naturalis 25-45, Os Draconis 3-8.

2. medicament as claimed in claim 1, is characterized in that, Borax 4-5, Haematitum 11-15, Radix Delphinii pogonanthi 14-16, Folium Nelumbinis 14-18, Rhizoma Pinelliae 11-13, Pericarpium Citri Reticulatae 9-11, Rhizoma Dioscoreae 33-37, Concha Ostreae 26-32, succinum 30-40, Marasmius equicrinis Muell. 10-14, Flos Carthami 8-10, Rhizoma Ligustici 9-12, Cinnabaris 4-7, Herba Apocyni veneti 10-14, Folium Citri tangerinae 9-12, Radix Rehmanniae 7-10, Radix Paeoniae Alba 10-14, Rhizoma Tupistrae Chinensis 8-13, Radix Cyathulae 11-16, Rhizoma Alismatis 12-16, Indigo Naturalis 30-40, Os Draconis 4-7.

3. medicament as claimed in claim 1, is characterized in that, Borax 4.5, Haematitum 13, Radix Delphinii pogonanthi 15, Folium Nelumbinis 16, the Rhizoma Pinelliae 12, Pericarpium Citri Reticulatae 10, Rhizoma Dioscoreae 35, Concha Ostreae 29, succinum 35, Marasmius equicrinis Muell. 12, Flos Carthami 9, Rhizoma Ligustici 10.5, Cinnabaris 6.5, Herba Apocyni veneti 12, Folium Citri tangerinae 10.5, Radix Rehmanniae 8.5, the Radix Paeoniae Alba 12, Rhizoma Tupistrae Chinensis 10.5, Radix Cyathulae 13.5, Rhizoma Alismatis 14, Indigo Naturalis 35, Os Draconis 5.5.

4. the medicament as described in as arbitrary in claim 1-3, is characterized in that, this medicament is made to pharmaceutically acceptable decoction, pill and thick paste agent.

5. medicament as claimed in claim 4, is characterized in that, the preparation method of described decoction is:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 120-180 mesh sieve, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, and is together placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, adds clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decocts for the first time 2-4 hour, decocts for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) step (1) gained fine powder is joined in above-mentioned decocting liquid, stir, sterile packaged, to obtain final product.

6. preparation method according to claim 5, is characterized in that, crosses 140-160 mesh sieve (preferred mistake 150 mesh sieves) in step (1).

7. preparation method according to claim 5, is characterized in that, the temperature that adds clear water in step (2) is 25-45 DEG C (preferably temperature is 30-40 DEG C, and being more preferably temperature is 35 DEG C).

8. medicament as claimed in claim 4, is characterized in that, the preparation method of described pill is:

(1) each crude drug was pulverized to 120-160 mesh sieve (preferably 130-150 mesh sieve), obtained fine powder;

(2) refined honey: Mel is placed in to evaporating dish and is heated to boil, continue to refine into refined honey degree, drag for floating foam band glossy;

(3) Mel of having refined is mixed in proportion to (ratio of medicated powder and refined honey is by weight being 1:1.5) with step (1) gained fine powder, make pill according to the preparation for processing of pill.

9. medicament as claimed in claim 4, is characterized in that, the preparation method of described thick paste agent is:

(1) Indigo Naturalis, Os Draconis, Cinnabaris are pulverized, crossed 120-180 mesh sieve, obtain fine powder;

(2) get Rhizoma Ligustici, Rhizoma Tupistrae Chinensis, Radix Cyathulae, clean, be placed in refractory container, with smokeless intense fire heating, be calcined to and be popular in, pour while hot stain in vinegar into and quench, take out, dry levigation;

(3) Haematitum, Borax, Concha Ostreae, succinum are smashed to pieces, Rhizoma Dioscoreae is thinly sliced, and is together placed in container with Radix Delphinii pogonanthi, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Marasmius equicrinis Muell., Herba Apocyni veneti, Radix Rehmanniae, Rhizoma Alismatis, adds clear water to soak 0.5-2 hour, step (2) gained fine powder is joined in above-mentioned medical material, big fire decocts twice, decocts for the first time 2-4 hour, decocts for the second time 1-3 hour, decoct and finish to add for first 0.5 hour the Radix Paeoniae Alba, Folium Nelumbinis, Flos Carthami and Folium Citri tangerinae for the second time, twice medicinal liquid mixes, and filters, and obtains decocting liquid;

(4) gained decocting liquid is carried out to distilling under reduced pressure, be condensed into paste; Then add step (1) gained fine powder, mix, cooling, obtain thick paste agent.

10. the application of the medicament as described in as arbitrary in claim 1-3 in the time that the medicine of hysteropsychosis is alleviated in preparation.