CN104083280A - Preparing method for boiled powder type traditional Chinese medicine decoction pieces - Google Patents
Preparing method for boiled powder type traditional Chinese medicine decoction pieces Download PDFInfo
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- CN104083280A CN104083280A CN201410369022.5A CN201410369022A CN104083280A CN 104083280 A CN104083280 A CN 104083280A CN 201410369022 A CN201410369022 A CN 201410369022A CN 104083280 A CN104083280 A CN 104083280A
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Abstract
The invention discloses a preparing method for boiled powder type traditional Chinese medicine decoction pieces. The method comprises the step one of cleansing, wherein single medicinal materials are screened to obtain crude medicinal materials; the step two of water cleaning, wherein the surface impurities of the crude medicinal materials are cleaned with drinking water; the step three of cutting, wherein the medicinal materials after being cleaned through the water are cut into pieces, or sections, or blocks or shreds; the step four of drying, wherein the medicinal materials after being cut are dried to the condition with the water content smaller than or equal to 5%; the step five of superfine grinding, wherein the dried medicinal materials are ground into superfine powder at low temperature; the step six of particle manufacturing, wherein the powder is manufactured into particles with the particle size of 12-40 meshes; the step seven of packaging, wherein the particles are mixed evenly, and packaged through aluminum packing film bags in a sealing mode. The preparing method has the advantages of being easy to operate, convenient to prepare and low in cost; according to products prepared through the method, surface area crushing is carried out to the largest degree, the dissolution rate of effective constituents is increased to the maximum, the amount of adopted traditional Chinese medicine decoction pieces is reduced, the medicinal materials are saved, dregs of decoction are avoided, and the pieces are convenient to take and store and free of side effect.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs field, particularly relate to a kind of preparation method of the decoction made from powder type prepared slices of Chinese crude drugs.
Background technology
Chinese medicine is the conventional medicament of China, and the greatest feature of Chinese medicine is exactly the prepared slices of Chinese crude drugs formula that uses single, varies with each individual, because of state of an illness difference, face disease formula, addition or subtraction of changes, only, by 600 kinds of conventional medical materials, thousands upon thousands prescriptions of just filling a prescription out, treat various diseases.For thousands of years, be generally that the prepared slices of Chinese crude drugs after formula are closed and decoct, abandon medicinal residues, drink medicinal liquid.
In recent years; there is report that single medicinal material material is condensed into granule through refining; make Chinese medicinal granule (be again Chinese prescription granule or exempt to decoct Chinese medicine), though easy to carry, need not decoct, mouthfeel is better, refines the origin that concentrated process has still departed from Chinese crude drug genuineness.Chinese patent ZL01114467.X discloses a kind of preparing superfine particles of Chinese medicine, is characterized in the dry the prepared slices of Chinese crude drugs rear superfine communication technique that adopts to make it become micropowders, then granulation.While taking, need to use boiled water to brew, this Chinese medicine ultramicro powder has only been avoided the trouble decocting, but does not improve for aspects such as drug effect absorption and mouthfeels.
Decoction made from powder, is that medicine is made to fine powder or coarse powder, and subpackage or used time take, and adds water or priming to decoct, together with medicine foam or a kind of dosage form taken that removes slag.Decoction made from powder has the following advantages: (1) has simplified the leaching condition of effective ingredient: can the effective ingredient in medicine be leached completely or retain, and directly affects clinical efficacy.As decoction made from powder agent, through pulverizing thick medical material, diffusion area increases, and stripping material increases, and dissolution rate is accelerated, and along with the increase of degree of grinding, the chance of cytoclasis increases, and cell Dissolve things inside directly contacts with water and dissolves, thereby leaching amount is increased; (2) can retain preferably volatile ingredient: overcome decoction in decoction boiling process, the defect that volatile ingredient almost volatilizees totally with steam; (3) shorten decocting time: the Chinese medicinal granule surface area of making due to decoction increases, and leaching rate improves, can at short notice effective ingredient have been leached, both saved the time, ensured again drug effect; (4) be conducive to the acute stages treated of chronic disease: some acute phase of disease is taken Chinese patent medicine, and often effect is undesirable, and decoction made from powder agent can compensate its defect; (5) be conducive to the selection of some disease to excipient: conventional dosage forms honeyed pill is taking Mel as excipient, and diabetes patient should not take, and as the common medicine that LIUWEI DIHUANG WAN is diabetes patient, this has brought difficulty to treatment; (6) saving resource: because decoction made from powder agent is by pulverizing medicinal materials granulation, medical material surface area is increased, effective ingredient leaches completely.
Therefore, how not only keep Chinese medicine tradition but also overcome the shortcoming of existence, General Promotion About The Quality of Sliced Herbal Medicine simultaneously, is the emphasis of current prepared slices of Chinese crude drugs research.
Summary of the invention
The object of the invention is to overcome the shortcoming of prior art, a kind of preparation method of the decoction made from powder type prepared slices of Chinese crude drugs is provided, that the method has advantages of is simple to operate, easy to prepare, cost is low, the product making by the inventive method is owing to having carried out surface area break process to greatest extent, the dissolution of its effective ingredient is improved to greatest extent, thereby reduced the consumption of Chinese medicine decoction pieces, saved medical material and without medicinal residues, taking convenience, be convenient to storage, have no side effect.
Object of the present invention is achieved through the following technical solutions: a kind of preparation method of the decoction made from powder type prepared slices of Chinese crude drugs, and it comprises the following steps:
S1. only make: choose single medical material, Chinese crude drug is screened, substandard products, the medical material that goes mouldy, dis-medicinal part are rejected, remove stone and the visible foreign material of clod, obtain clean medical material;
s2. water system: clean pharmacy material is dropped in rinsing bowl or rinsing machine with drinking water clean surface impurity;
S3. cutting: the medical material after water system is cut into lamellar, section shape, square shape or thread, and described sheet thickness is 2~5mm, section shape length is 5~15mm, and the square shape length of side is 8~12mm, and thread fineness is 3~8mm;
S4. dry: the medical material after cutting is dried, and baking temperature is controlled at 50~60 DEG C, is dried to medical material water content≤5%;
S5. micronizing: dried processing of crude drugs is become to ultra-micro powder, control temperature at-40 DEG C~-60 DEG C, fineness of powder is 100~1000 orders, and by powder mix homogeneously;
S6. granulate: using granulation machine to add the ethanol of purified water or 75~97% concentration to make particle diameter in the powder of above-mentioned mix homogeneously is 12~40 object granules;
S7. packaging: by the above-mentioned granule mix homogeneously making, granule is packed with aluminum-plastic composite membrane bag, every bag is packaged into 1~10g, makes the decoction made from powder type prepared slices of Chinese crude drugs.
Further, any one in dry employing far-infrared ray drying, microwave drying or hot air drying described in step S4.
Further, in step S5, adopt the method for comminution by gas stream or mechanical activation comminution that dried processing of crude drugs is become to ultra-micro powder.
Further, the weight ratio of powder and purified water or ethanol described in step S6 is 1:0.1-0.2.
Further, every bag of fractional pack that is packaged into 1g, 2g, 3g, 5g, 6g or 10g described in step S7.
The decoction made from powder type prepared slices of Chinese crude drugs prepared by the inventive method only need used time 5min to complete to boil medicine in the time boiling medicine.
The present invention has the following advantages:
(1) Chinese crude drug has been carried out pulverizing at ultralow temperature processing by the present invention, the crusher surface that has increased to greatest extent medical material is long-pending, the dissolution of its effective ingredient is significantly improved, thereby has reduced the consumption of Chinese medicine decoction pieces, and the administration features that has kept Traditional Chinese Medicine " to close and decoct ";
(2) in preparation method of the present invention, do not add any type of additive and antiseptic, be significantly different from all kinds of Chinese patent medicines of additives such as containing at present antiseptic, Pulvis Talci, white sugar, be therefore applicable to all kinds of crowds, and have no side effect;
(3) take, easy to carry: while adopting the prepared slices of Chinese crude drugs prepared of the inventive method to boil medicine, only need used time 5min, Chinese medicine decoction pieces at least to need just can complete to boil medicine for nearly one hour to take medicine, decocted time shorten more than 5 times than conventional formulation decoction pieces;
(4) the inventive method all adopts powder, forms suspension closing in the process of decocting, and patient can all swallow, and therefore, without medicinal residues, has reduced the pollution to environment;
(5) content of its extractum of finished product that prepared by the inventive method is higher more than 5 times than traditional decoction pieces, has greatly saved herb resource.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described, and protection scope of the present invention is not limited to the following stated.
embodiment 1:a preparation method for the decoction made from powder type Ganoderma prepared slices of Chinese crude drugs, it comprises the following steps:
S1. only make: choose Ganoderma Chinese crude drug, Ganoderma Chinese crude drug is screened, substandard products, the medical material that goes mouldy, dis-medicinal part are rejected, remove stone and the visible foreign material of clod, obtain clean medical material;
s2. water system: the Ganoderma of only making is dropped in rinsing bowl with drinking water clean surface impurity;
S3. cutting: the Ganoderma after water system is cut into lamellar, and described sheet thickness is 2~5mm;
S4. dry: the Ganoderma after cutting is adopted to far-infrared ray drying, and baking temperature is controlled at 50 DEG C, and being dried to medical material water content is 5%;
S5. micronizing: adopt the mode of comminution by gas stream to be processed into ultra-micro powder dried Ganoderma, control temperature at-40 DEG C, fineness of powder is 100 orders, and by powder mix homogeneously;
S6. granulate: using granulation machine to add purified water to make particle diameter in the powder of above-mentioned mix homogeneously is 12 object granules; The weight ratio of described powder and purified water is 1:0.1.
S7. packaging: by the above-mentioned granule mix homogeneously making, granule is packed with aluminum-plastic composite membrane bag, every bag is packaged into the fractional pack of 1g, 2g, 3g, 5g, 6g or 10g.
embodiment 2:a preparation method for the decoction made from powder type Fructus Jujubae prepared slices of Chinese crude drugs, it comprises the following steps:
S1. only make: choose Fructus Jujubae, Fructus Jujubae is screened, substandard products, the medical material that goes mouldy, dis-medicinal part are rejected, remove stone and the visible foreign material of clod, obtain clean medical material;
s2. water system: Fructus Jujubae processed drops in rinsing machine with drinking water clean surface impurity only;
S3. cutting: the Fructus Jujubae after water system is cut into the lamellar that thickness is 2~5mm;
S4. dry: adopt the mode of hot air drying to be dried in the Fructus Jujubae after cutting, baking temperature is controlled at 60 DEG C, and being dried to medical material water content is 4%;
S5. micronizing: adopt the mode of mechanical activation comminution to be processed into ultra-micro powder in dried Fructus Jujubae, control temperature at-60 DEG C, fineness of powder is 1000 orders, and by powder mix homogeneously;
S6. granulate: using granulation machine to add the ethanol of 75% concentration to make particle diameter in the powder of above-mentioned mix homogeneously is 40 object granules; The weight ratio of described powder and ethanol is 1:0.1;
S7. packaging: by the above-mentioned granule mix homogeneously making, granule is packed with aluminum-plastic composite membrane bag, every bag is packaged into the fractional pack of 1g, 2g, 3g, 5g, 6g or 10g, makes the decoction made from powder type Fructus Jujubae prepared slices of Chinese crude drugs.
embodiment 3:a preparation method for the decoction made from powder type Rhizoma Atractylodis Macrocephalae (parched with bran) prepared slices of Chinese crude drugs, it comprises the following steps:
S1. only make: choose Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis Macrocephalae Chinese crude drug is screened, substandard products, the medical material that goes mouldy, dis-medicinal part are rejected, remove stone and the visible foreign material of clod, obtain clean medical material;
s2. water system: Rhizoma Atractylodis Macrocephalae processed drops in rinsing bowl with drinking water clean surface impurity only;
S3. cutting: the Rhizoma Atractylodis Macrocephalae after water system is cut into the lamellar that thickness is 2~5mm;
S4. dry: adopt microwave to be dried the Rhizoma Atractylodis Macrocephalae after cutting, baking temperature is controlled at 55 DEG C, and being dried to medical material water content is 3%;
S5. concoct: processed with honey wheat bran is sprinkled in heat pot, adds Rhizoma Atractylodis Macrocephalae sheet in the time smoldering, fry to yellowish-brown, effusion burnt odor gas, take out, sieve removes processed with honey wheat bran, obtains Rhizoma Atractylodis Macrocephalae (parched with bran) decoction pieces;
S6. micronizing: adopt the mode of comminution by gas stream to be processed into ultra-micro powder Rhizoma Atractylodis Macrocephalae (parched with bran) decoction pieces, control temperature at-45 DEG C, fineness of powder is 200 orders, and by powder mix homogeneously;
S7. granulate: using granulation machine to add purified water to make particle diameter in the powder of above-mentioned mix homogeneously is 24 object granules; The weight ratio of described powder and purified water is 1:0.2;
S7. packaging: by the above-mentioned granule mix homogeneously making, granule is packed with aluminum-plastic composite membrane bag, every bag is packaged into the fractional pack of 1g, 2g, 3g, 5g, 6g or 10g, makes the decoction made from powder type prepared slices of Chinese crude drugs.
embodiment 4:a preparation method for the decoction made from powder type Pericarpium Citri Reticulatae prepared slices of Chinese crude drugs, it comprises the following steps:
S1. only make: choose Pericarpium Citri Reticulatae Chinese crude drug, Pericarpium Citri Reticulatae Chinese crude drug is screened, substandard products, the medical material that goes mouldy, dis-medicinal part are rejected, remove stone and the visible foreign material of clod, obtain clean medical material;
s2. water system: Pericarpium Citri Reticulatae Chinese crude drug processed drops in rinsing machine with drinking water clean surface impurity only;
S3. cutting: the Pericarpium Citri Reticulatae medical material after water system is cut into thread, described thread fineness is 3~8mm;
S4. dry: adopt the mode of far-infrared ray drying to be dried the Pericarpium Citri Reticulatae medical material after cutting, baking temperature is controlled at 58 DEG C, and being dried to medical material water content is 2%;
S5. micronizing: adopt the mode of mechanical activation comminution to be processed into ultra-micro powder dried Pericarpium Citri Reticulatae medical material, control temperature at-52 DEG C, fineness of powder is 800 orders, and by powder mix homogeneously;
S6. granulate: using granulation machine to add the ethanol of 97% concentration to make particle diameter in the powder of above-mentioned mix homogeneously is 20 object granules; The weight ratio of described powder and ethanol is 1:0.2;
S7. packaging: by the above-mentioned granule mix homogeneously making, granule is packed with aluminum-plastic composite membrane bag, every bag is packaged into the fractional pack of 1g, 2g, 3g, 5g, 6g or 10g, makes the decoction made from powder type Pericarpium Citri Reticulatae prepared slices of Chinese crude drugs.
Claims (5)
1. a preparation method for the decoction made from powder type prepared slices of Chinese crude drugs, is characterized in that, it comprises the following steps:
S1. only make: choose single medical material, Chinese crude drug is screened, substandard products, the medical material that goes mouldy, dis-medicinal part are rejected, remove stone and the visible foreign material of clod, obtain clean medical material;
S2. water system: clean pharmacy material is dropped in rinsing bowl or rinsing machine with drinking water clean surface impurity;
S3. cutting: the medical material after water system is cut into lamellar, section shape, square shape or thread, and described sheet thickness is 2~5mm, section shape length is 5~15mm, and the square shape length of side is 8~12mm, and thread fineness is 3~8mm;
S4. dry: the medical material after cutting is dried, and baking temperature is controlled at 50~60 DEG C, is dried to medical material water content≤5%;
S5. micronizing: dried processing of crude drugs is become to ultra-micro powder, control temperature at-40 DEG C~-60 DEG C, fineness of powder is 100~1000 orders, and by powder mix homogeneously;
S6. granulate: using granulation machine to add the ethanol of purified water or 75~97% concentration to make particle diameter in the powder of above-mentioned mix homogeneously is 12~40 object granules;
S7. packaging: by the above-mentioned granule mix homogeneously making, granule is packed with aluminum-plastic composite membrane bag, every bag is packaged into 1~10g, makes the decoction made from powder type prepared slices of Chinese crude drugs.
2. the preparation method of a kind of decoction made from powder type prepared slices of Chinese crude drugs as claimed in claim 1, is characterized in that, any one described in step S4 in dry employing far-infrared ray drying, microwave drying or hot air drying.
3. the preparation method of a kind of decoction made from powder type prepared slices of Chinese crude drugs as claimed in claim 1, is characterized in that, adopts the method for comminution by gas stream or mechanical activation comminution that dried processing of crude drugs is become to ultra-micro powder in step S5.
4. the preparation method of a kind of decoction made from powder type prepared slices of Chinese crude drugs as claimed in claim 1, is characterized in that, the weight ratio of powder described in step S6 and purified water or ethanol is 1:0.1~0.2.
5. the preparation method of a kind of decoction made from powder type prepared slices of Chinese crude drugs as claimed in claim 1, is characterized in that, described in step S7, every bag is packaged into the fractional pack of 1g, 2g, 3g, 5g, 6g or 10g.
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Cited By (4)
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CN104523430A (en) * | 2014-12-17 | 2015-04-22 | 吉林敖东世航药业股份有限公司 | Freezing low-temperature superfine grinding method for traditional Chinese medicine |
CN106733065A (en) * | 2015-11-23 | 2017-05-31 | 威海康博尔生物药业有限公司 | A kind of Chinese medicine nanometer pulverization method |
CN110026282A (en) * | 2019-05-31 | 2019-07-19 | 重庆文理学院 | Chinese medicine breaking method |
CN116059107A (en) * | 2021-11-01 | 2023-05-05 | 广东美的生活电器制造有限公司 | Medicinal material processing method, device, apparatus and storage medium |
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CN101147746A (en) * | 2006-09-18 | 2008-03-26 | 中山市中智药业集团有限公司 | Method for processing traditional Chinese herbs broken wall powder |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104523430A (en) * | 2014-12-17 | 2015-04-22 | 吉林敖东世航药业股份有限公司 | Freezing low-temperature superfine grinding method for traditional Chinese medicine |
CN106733065A (en) * | 2015-11-23 | 2017-05-31 | 威海康博尔生物药业有限公司 | A kind of Chinese medicine nanometer pulverization method |
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CN116059107A (en) * | 2021-11-01 | 2023-05-05 | 广东美的生活电器制造有限公司 | Medicinal material processing method, device, apparatus and storage medium |
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Application publication date: 20141008 |