CN103721257B - 光敏素催化分解过氧化氢系列药物 - Google Patents
光敏素催化分解过氧化氢系列药物 Download PDFInfo
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- CN103721257B CN103721257B CN201210390725.7A CN201210390725A CN103721257B CN 103721257 B CN103721257 B CN 103721257B CN 201210390725 A CN201210390725 A CN 201210390725A CN 103721257 B CN103721257 B CN 103721257B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0042—Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/20—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Radiation-Therapy Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (12)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210390725.7A CN103721257B (zh) | 2012-10-16 | 2012-10-16 | 光敏素催化分解过氧化氢系列药物 |
JP2012283972A JP6068132B2 (ja) | 2012-10-16 | 2012-12-27 | フィトクロームで過酸化水素の分解を触媒するシリーズ薬物 |
KR20120156537A KR101487008B1 (ko) | 2012-10-16 | 2012-12-28 | 과산화수소의 분해를 촉매하는 포토프린을 사용한 일련의 약물 |
EP13150173.6A EP2722057A3 (en) | 2012-10-16 | 2013-01-03 | A series of drugs using photofrin to catalyze decomposition of hydrogen peroxide |
DE13150173.6T DE13150173T1 (de) | 2012-10-16 | 2013-01-03 | Reihe von Arzneimitteln, die Photofrin zum Katalysieren der Zersetzung von Wasserstoffperoxid verwenden |
US13/734,442 US20140107332A1 (en) | 2012-10-16 | 2013-01-04 | Series of drugs using photofrin to catalyze decomposition of hydrogen peroxide |
US14/608,959 US20150141478A1 (en) | 2012-10-16 | 2015-01-29 | Series of drugs using photofrin to catalyze decomposition of hydrogen peroxide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210390725.7A CN103721257B (zh) | 2012-10-16 | 2012-10-16 | 光敏素催化分解过氧化氢系列药物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103721257A CN103721257A (zh) | 2014-04-16 |
CN103721257B true CN103721257B (zh) | 2016-12-21 |
Family
ID=47563172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210390725.7A Expired - Fee Related CN103721257B (zh) | 2012-10-16 | 2012-10-16 | 光敏素催化分解过氧化氢系列药物 |
Country Status (6)
Country | Link |
---|---|
US (2) | US20140107332A1 (zh) |
EP (1) | EP2722057A3 (zh) |
JP (1) | JP6068132B2 (zh) |
KR (1) | KR101487008B1 (zh) |
CN (1) | CN103721257B (zh) |
DE (1) | DE13150173T1 (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103405769A (zh) * | 2013-03-07 | 2013-11-27 | 北京亿仁赛博医疗科技研发中心有限公司 | 光敏剂在制备治疗疾病的病毒灭活药物中的应用 |
CN103432581A (zh) * | 2013-03-22 | 2013-12-11 | 北京海思威科技有限公司 | 速立氧注射剂在制备治疗疾病的病毒灭活中的应用 |
WO2019165338A1 (en) * | 2018-02-23 | 2019-08-29 | Ladizinsky Daniel A | Oxygenating oral and topical compositions |
CN112704735B (zh) * | 2020-12-22 | 2022-03-18 | 山西大学 | 一种无机离子介导的有机化合物纳米酶及制备方法和应用 |
WO2023181623A1 (ja) * | 2022-03-23 | 2023-09-28 | 国立大学法人大阪大学 | 電子ビーム照射装置及び電子ビーム照射方法 |
CN114904040B (zh) * | 2022-05-18 | 2023-06-13 | 四川大学 | 一种乳酸响应的光激活抗菌敷料 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60219627T2 (de) * | 2001-06-04 | 2008-02-07 | The General Hospital Corp., Boston | Nachweis und therapie von empfindlichem plaque mit photodynamischen verbindungen |
CN1336174A (zh) * | 2001-08-27 | 2002-02-20 | 董国臣 | X线激发氧化锌卟啉化合物光动力作用的组合物抗癌光弹 |
OA12720A (en) * | 2001-11-09 | 2006-06-27 | Eyetech Pharmaceuticals | Methods for treating ocular neovascular diseases. |
CN101583366B (zh) * | 2006-09-22 | 2013-02-06 | 国立大学法人高知大学 | 放射增敏剂或抗癌化学疗法增敏剂 |
JP5182858B2 (ja) * | 2007-12-26 | 2013-04-17 | 独立行政法人産業技術総合研究所 | X線治療用増感剤 |
JP2010053079A (ja) * | 2008-08-28 | 2010-03-11 | Toin Gakuen | 5−アミノレブリン酸誘導体及びその塩 |
GB0819594D0 (en) * | 2008-10-24 | 2008-12-03 | Univ Coimbrra | Process |
AU2009347929A1 (en) | 2009-06-12 | 2012-01-19 | Amrita Vishwa Vidyapeetham University | Targeted nano-photomedicines for photodynamic therapy of cancer |
JP2010284399A (ja) * | 2009-06-15 | 2010-12-24 | Yayoi:Kk | 光線力学的治療装置 |
KR20110035725A (ko) * | 2009-09-30 | 2011-04-06 | (주)바이오버드 | 광역동 치료법에 이용되는 광감작제로서의 신규한 화합물 |
FR2971942A1 (fr) * | 2011-02-28 | 2012-08-31 | Centre Nat Rech Scient | Systeme generant des especes reactives de l'oxygene pour utilisation comme medicament dans le traitement du cancer |
CN103405769A (zh) * | 2013-03-07 | 2013-11-27 | 北京亿仁赛博医疗科技研发中心有限公司 | 光敏剂在制备治疗疾病的病毒灭活药物中的应用 |
-
2012
- 2012-10-16 CN CN201210390725.7A patent/CN103721257B/zh not_active Expired - Fee Related
- 2012-12-27 JP JP2012283972A patent/JP6068132B2/ja not_active Expired - Fee Related
- 2012-12-28 KR KR20120156537A patent/KR101487008B1/ko active IP Right Grant
-
2013
- 2013-01-03 EP EP13150173.6A patent/EP2722057A3/en not_active Withdrawn
- 2013-01-03 DE DE13150173.6T patent/DE13150173T1/de active Pending
- 2013-01-04 US US13/734,442 patent/US20140107332A1/en not_active Abandoned
-
2015
- 2015-01-29 US US14/608,959 patent/US20150141478A1/en not_active Abandoned
Non-Patent Citations (1)
Title |
---|
Novel applications of diagnostic X-rays in activating a clinical photodynamic drug: Photofrin II through X-ray induced visible luminescence from "rare-earth" formulated particles;Erkinay Abliza 等;《Journal of X-Ray Science and Technology》;20111231;第19卷;第521–530页,标题、摘要 * |
Also Published As
Publication number | Publication date |
---|---|
JP2014079552A (ja) | 2014-05-08 |
CN103721257A (zh) | 2014-04-16 |
JP6068132B2 (ja) | 2017-01-25 |
EP2722057A2 (en) | 2014-04-23 |
KR20140048777A (ko) | 2014-04-24 |
DE13150173T1 (de) | 2015-10-01 |
EP2722057A3 (en) | 2014-04-30 |
US20140107332A1 (en) | 2014-04-17 |
KR101487008B1 (ko) | 2015-01-27 |
US20150141478A1 (en) | 2015-05-21 |
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C06 | Publication | ||
PB01 | Publication | ||
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SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: WUXI ZHAOZHEN RADIATION TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: BEIJING TOP GRADE KANGMING MEDICAL DEVICES INC. Effective date: 20140917 |
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C41 | Transfer of patent application or patent right or utility model | ||
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Free format text: CORRECT: ADDRESS; FROM: 100176 CHAOYANG, BEIJING TO: 214000 WUXI, JIANGSU PROVINCE |
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TA01 | Transfer of patent application right |
Effective date of registration: 20140917 Address after: 214000 Jiangsu Province, Wuxi city Huishan District Yanqiao Street weir Road Applicant after: WUXI ZHAOZHEN RADIATION TECHNOLOGY CO., LTD. Address before: 100176 No. 11 Yongchang North Road, Beijing Economic Development Zone Applicant before: Beijing Top Grade Medical Equipment Co., Ltd. |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161221 Termination date: 20191016 |
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CF01 | Termination of patent right due to non-payment of annual fee |