CN103330938A - 肿瘤靶向性光敏剂及其制备方法与应用 - Google Patents
肿瘤靶向性光敏剂及其制备方法与应用 Download PDFInfo
- Publication number
- CN103330938A CN103330938A CN2013102916910A CN201310291691A CN103330938A CN 103330938 A CN103330938 A CN 103330938A CN 2013102916910 A CN2013102916910 A CN 2013102916910A CN 201310291691 A CN201310291691 A CN 201310291691A CN 103330938 A CN103330938 A CN 103330938A
- Authority
- CN
- China
- Prior art keywords
- ppix
- hsa
- photosensitizer
- carboxylic acid
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Description
Claims (11)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310291691.0A CN103330938B (zh) | 2013-07-11 | 2013-07-11 | 肿瘤靶向性光敏剂及其制备方法与应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310291691.0A CN103330938B (zh) | 2013-07-11 | 2013-07-11 | 肿瘤靶向性光敏剂及其制备方法与应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103330938A true CN103330938A (zh) | 2013-10-02 |
CN103330938B CN103330938B (zh) | 2015-04-29 |
Family
ID=49239188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310291691.0A Active CN103330938B (zh) | 2013-07-11 | 2013-07-11 | 肿瘤靶向性光敏剂及其制备方法与应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103330938B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019003155A1 (en) * | 2017-06-27 | 2019-01-03 | Vision Global Holdings Limited | COMPOSITIONS FOR PHOTODYNAMIC THERAPY AND FLUORESCENCE DIAGNOSIS OF CANCERS AND OTHER DISEASES |
CN113117099A (zh) * | 2019-12-31 | 2021-07-16 | 广东精观生物医药科技有限公司 | 一种靶向psma的荧光分子探针及其制备方法和应用 |
CN113384709A (zh) * | 2021-06-28 | 2021-09-14 | 西南大学 | 一种葡聚糖-原卟啉前药纳米胶束的制备和应用 |
-
2013
- 2013-07-11 CN CN201310291691.0A patent/CN103330938B/zh active Active
Non-Patent Citations (3)
Title |
---|
G. I.LOZOVAYA ET AL.: "Protoporphyrin Ix As A Possible Ancient Photosensitizer: Spectral And Photochemical Studies", 《ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE》 * |
SARAH C. ROZINEK ET AL.: "Photoinduced conformational changes of human serum albumin bound to protoporphyrin IX and hemin", 《PROC.SPIE》 * |
TERUYUKI KOMATSU ET AL.: "Structural and Mutagenic Approach to Create Human Serum Albumin-Based Oxygen Carrier and Photosensitizer. Teruyuki Komatsu et al. Drug Metab. Pharmacokinet. 24 (4): 287–299 (2009)", 《DRUG METAB. PHARMACOKINET》 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019003155A1 (en) * | 2017-06-27 | 2019-01-03 | Vision Global Holdings Limited | COMPOSITIONS FOR PHOTODYNAMIC THERAPY AND FLUORESCENCE DIAGNOSIS OF CANCERS AND OTHER DISEASES |
US10946099B2 (en) | 2017-06-27 | 2021-03-16 | Vision Global Holdings Limited | Compositions for photodynamic therapy and fluorescence diagnosis of cancers and other diseases |
CN113117099A (zh) * | 2019-12-31 | 2021-07-16 | 广东精观生物医药科技有限公司 | 一种靶向psma的荧光分子探针及其制备方法和应用 |
CN113117099B (zh) * | 2019-12-31 | 2022-07-15 | 广东精观生物医药科技有限公司 | 一种靶向psma的荧光分子探针及其制备方法和应用 |
CN113384709A (zh) * | 2021-06-28 | 2021-09-14 | 西南大学 | 一种葡聚糖-原卟啉前药纳米胶束的制备和应用 |
CN113384709B (zh) * | 2021-06-28 | 2022-03-11 | 西南大学 | 一种葡聚糖-原卟啉前药纳米胶束的制备和应用 |
Also Published As
Publication number | Publication date |
---|---|
CN103330938B (zh) | 2015-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Yu et al. | Oxygen self-sufficient NIR-activatable liposomes for tumor hypoxia regulation and photodynamic therapy | |
Patel et al. | Highly effective dual-function near-infrared (NIR) photosensitizer for fluorescence imaging and photodynamic therapy (PDT) of cancer | |
Yang et al. | Self-illuminating photodynamic therapy with enhanced therapeutic effect by optimization of the chemiluminescence resonance energy transfer step to the photosensitizer | |
Li et al. | cRGD peptide-conjugated pyropheophorbide-a photosensitizers for tumor targeting in photodynamic therapy | |
CN104940950B (zh) | 一种肿瘤靶向多肽光敏剂键合物 | |
CN107899013B (zh) | 一种具有光动力学治疗开关效应及分子识别作用的介孔二氧化锰纳米载药***的制备方法 | |
Xu et al. | Highly stable organic photothermal agent based on near-infrared-II fluorophores for tumor treatment | |
CN103585644A (zh) | 一种聚乙二醇修饰的磁性纳米颗粒及其应用 | |
CN103316340A (zh) | 一种具有等离子光热/光动力治疗性能的金纳米复合粒子及其制备方法 | |
CN106866721B (zh) | 一种硅酞菁衍生物及其制备生物素受体靶向硅酞菁光敏剂的应用 | |
Yang et al. | Sensitive, real-time, and in-vivo oxygen monitoring for photodynamic therapy by multifunctional mesoporous nanosensors | |
Atmaca | Investigation of singlet oxygen efficiency of di-axially substituted silicon phthalocyanine with sono-photochemical and photochemical studies | |
CN107469079B (zh) | 一种t1-mri成像引导下的光动治疗剂制备方法 | |
US20240041787A1 (en) | Photosensitizer molecule and use thereof in increasing tumor retention time and enhancing treatment of large-volume tumors | |
Chen et al. | Gadolinium–porphyrin based polymer nanotheranostics for fluorescence/magnetic resonance imaging guided photodynamic therapy | |
Zhao et al. | The substituted zinc (II) phthalocyanines using “sulfur bridge” as the linkages. Synthesis, red-shifted spectroscopic properties and structure-inherent targeted photodynamic activities | |
Cheng et al. | Self-assembled nano-photosensitizer for targeted, activatable, and biosafe cancer phototheranostics | |
Mai et al. | Improved IR780 derivatives bearing morpholine group as tumor-targeted therapeutic agent for near-infrared fluorescence imaging and photodynamic therapy | |
CN103330938B (zh) | 肿瘤靶向性光敏剂及其制备方法与应用 | |
CN113683602B (zh) | 一种用于缺氧肿瘤多模态治疗的七甲川花菁小分子和制备方法及应用 | |
Xu et al. | Defective transition metal hydroxide-based nanoagents with hypoxia relief for photothermal-enhanced photodynamic therapy | |
CN109420181A (zh) | 一种用于肿瘤荧光成像及光热/光动力治疗的多功能纳米粒子 | |
Morozova et al. | Photodiagnosis and photodynamic effects of bacteriochlorin-naphthalimide conjugates on tumor cells and mouse model | |
Boscencu et al. | Porphyrin macrocycles: General properties and theranostic potential | |
CN111560033A (zh) | 一种光控释化合物的合成方法及在肿瘤治疗中的应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20180322 Address after: 100085 room, room 5, No. 5, Haidian District Road, Beijing, China Patentee after: BEIJING FUNAKANG BIOTECHNOLOGY CO., LTD. Address before: 100080 Haidian District, Zhongguancun, North Street, No. 1, No. 2, Beijing Patentee before: Institute of Chemistry, Chinese Academy of Sciences |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20201111 Address after: No.9 Wanze Avenue, Hongshan Economic Development Zone, Chifeng City, Inner Mongolia Autonomous Region 024000 Chifeng Funakang Biotechnology Co., Ltd Patentee after: Chifeng Funakang Biotechnology Co.,Ltd. Patentee after: Beijing Fullcan Biotechnology Co.,Ltd. Address before: 100085, 523, 5, 5, Pioneer Road, Beijing, Haidian District Patentee before: Beijing Fullcan Biotechnology Co.,Ltd. |
|
TR01 | Transfer of patent right |