CN103721125A - Medicament for treating gout and preparation method thereof - Google Patents
Medicament for treating gout and preparation method thereof Download PDFInfo
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- CN103721125A CN103721125A CN201410027714.1A CN201410027714A CN103721125A CN 103721125 A CN103721125 A CN 103721125A CN 201410027714 A CN201410027714 A CN 201410027714A CN 103721125 A CN103721125 A CN 103721125A
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Abstract
The invention relates to the field of medicine, and in particular relates to a medicament for treating gout and a preparation method thereof. The medicament for treating gout comprises the following raw material components in parts by weight: 10-50 parts of Indian iphigenia bulb, 30-120 parts of plantain seed, 20-60 parts of prepared common monkshood mother root and kusnezoff monkshood root, 50-150 parts of coix seed, 30-120 parts of oriental waterplantain rhizome, 30-100 parts of clematis root, 20-80 parts of white mustard seed, 20-60 parts of fourstamen stephania root, 20-100 parts of glabrous greenbrier rhizome, 10-60 parts of cassia twig, 50-200 parts of white paeony root, 40-80 parts of Chinese angelica and 30-120 parts of twotooth achyranthes root. By using the medicament for treating gout provided by the embodiment of the invention, a gout treatment effect can be achieved with no damages (or little damages) to the gastrointestinal tract, kidney and liver of the human body.
Description
Technical field
The present invention relates to field of medicaments, in particular to a kind of medicine that is used for the treatment of gout and preparation method thereof.
Background technology
Gout is one group of syndrome due to human body purine metabolic disturbance.According to pathogenic factor, can be divided into two types of primary gout and secondary gouts.Primary gout has obvious Family inherited inclination, is mainly in middle-aged and elderly people, and onset peak is 30-50 year, and approximately 95% is male, and 5% women is often sequela in menopause.Secondary gout except secondary gout onset due to congenital Fanconi-de Toni syndrome and chronic renal failure slowly, a lot of diseases are more anxious.
In medical domain, for gout, in correlation technique, medicine (probenecid, sulfinic acid draw ancestor, benzbromarone) the treatment gout of the multiplex analgesic of people (as colchicine, NSAID (non-steroidal anti-inflammatory drug), Adrenal Glucocorticoid) and reduction blood uric acid.
But medicine used mostly is Western medicine in correlation technique, after its long-term taking, can cause compared with macrolesion the gastrointestinal tract of human body, kidney and liver.
Summary of the invention
The object of the present invention is to provide a kind of medicine that is used for the treatment of gout, to solve the above problems.
Another object of the present invention is to provide a kind of preparation method that is used for the treatment of the medicine of gout.
A kind of medicine that is used for the treatment of gout is provided in an embodiment of the present invention, and according to parts by weight meter, its material component comprises:
Pseudobulbus Cremastrae Seu Pleiones 10-50 part, Semen Plantaginis 30-120 part, system two black 20-60 parts, Semen Coicis 50-150 part, Rhizoma Alismatis 30-120 part, Radix Clematidis 30-100 part, Semen Sinapis Albae 20-80 part, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae 20-100 part, Ramulus Cinnamomi 10-60 part, Radix Paeoniae Alba 50-200 part, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae 30-120 part.
The medicine that is used for the treatment of gout that the embodiment of the present invention provides, its material component is natural kind of medical herbs of set parts by weight.Concrete, Pseudobulbus cremastrae seu pleiones has the disappear effect of pain of heat-clearing and toxic substances removing, eliminating stagnation, wherein, containing multiple alkaloid, has good analgesic effect; Semen Plantaginis has the effect of relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, diuresis antiinflammatory; Make two crows and have wind-damp dispelling, the pain relieving of loose plug, be very suitable for treating arthralgia aggravated by cold, it,, containing multiple alkaloid, has good antiinflammatory, analgesia and local anesthetic action; Semen Coicis has the effect of promoting diuresis to eliminate damp pathogen, eliminating impediment.< < Sheng Nong's herbal classic > > records: the main muscular contracture of Semen Coicis is arrested twin, unable to flex and stretch the extremities, rheumatism numbness and the therapeutic method to keep the adverse QI flowing downwards, for a long time the clothes QI invigorating of making light of one's life by commiting suicide; Rhizoma Alismatis has the effect of promoting diuresis to eliminate damp pathogen, is the principal agent of diuretic; The Radix Clematidis benefaction twelve regular channels, has good dredging collateral effect; Semen Sinapis possesses promoting QI to circulate and dispersing the agglomeration of the pathogens, drives the effect of the outer expectorant of flesh side film; Radix Stephaniae Tetrandrae possesses the effect of wind-damp dispelling pain relieving, clearing away heat and promoting diuresis, and deficiency and excess is all available, for treating edema due to wind pathogen key medicine; Rhizoma Smilacis Glabrae possesses heat-clearing and toxic substances removing, the effect of dampness removing.The just > > of < < book on Chinese herbal medicine records its dampness removing and reduces phlegm and internal heat, and can enter network, searches and picks the damp and hot poison that accumulates; For Ramulus Cinnamomi, the < < book on Chinese herbal medicine > > that looks for the truth records it and dispels the wind loosely evil, is expelling pathogenic factors from muscles the first key medicine, and Ramulus Cinnamomi cuts down, for exterior symptoms in warming the meridian and promoting blood circulation all suitable; The Radix Paeoniae Alba possesses the effect of the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, relieving spasm to stop pain, the contracture pain of spasm of muscles and vessels; Radix Angelicae Sinensis possesses to enrich blood invigorates blood circulation, regulating menstruation, pain relieving, cures the wound and make each effect of returning to some extent of QI and blood; Radix Achyranthis Bidentatae possesses blood and dissolving stasis, invigorating the liver and kidney, bone and muscle strengthening, it is descending to ignite, and that relieving stranguria by diuresis, property are fallen is kind descending, draw the descending effect of all medicines; This medicine that is used for the treatment of gout that the embodiment of the present invention provides contains above-mentioned active princlple, and its strengthening body resistance and dispelling evil, radicallys reform, and energy fast reducing serum Uric Acid Concentration, recovers body metabolism.Because above-mentioned active drug component is all used pure natural Chinese herbal medicine, all medicines can share and alleviate GI irritation, also can well avoid the damage to liver and kidney.Therefore, the embodiment of the present invention provides this medicine that is used for the treatment of gout its when can realize treatment gout effect, also can not cause damage (or damaging minimum) to the gastrointestinal tract of human body, kidney and liver.
In addition, this medicine of the embodiment of the present invention, its active princlple all adopts pure natural Chinese herbal medicine, can effectively treat damp and hot, gout and metabolic arthritis card due to expectorant stasis blocking is stagnant.Righting evil removing original is refrigerant, can quick adjustment body, and reduce serum Uric Acid Concentration, recover organism metabolism, and to goat short treating period, pain relieving is rapid, and cure rate is high, and general 3 to 6 days i.e. effects are economical and practical.
Optionally, according to parts by weight meter, its material component also comprises: Pseudobulbus Cremastrae Seu Pleiones 20-40 part, Semen Plantaginis 25-80 part, system two black 25-55 parts, Semen Coicis 60-100 part, Rhizoma Alismatis 40-100 part, Radix Clematidis 40-90 part, Semen Sinapis Albae 30-70 part, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae 40-80 part, Ramulus Cinnamomi 20-50 part, Radix Paeoniae Alba 60-180 part, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae 40-80 part.
Optionally, according to parts by weight meter, its material component also comprises Radix Angelicae Pubescentis 20-60 part, Olibanum 10-30 part, Radix Et Rhizoma Rhei 20-60 part, Caulis Akebiae 30-60 part.
Optionally, according to parts by weight meter, its material component also comprises Radix Gentianae Macrophyllae 20-60 part, Rhizoma Atractylodis 20-60 part processed, Fructus Crataegi 10-50 part, Radix Glycyrrhizae 10-50 part, Fructus Chaenomelis 30-120 part, Caulis Trachelospermi 30-150 part, Radix Scutellariae 15-60, Herba speranskiae tuberculatae 20-100 part.
Optionally, described Radix Clematidis comprises the root of Wheeling Herba mesonae chinensis.
Optionally, the dosage form that is used for the treatment of the medicine of gout described in is decoction.
A kind of preparation method that is used for the treatment of the medicine of gout provided by the invention, comprises the following steps:
The Pseudobulbus Cremastrae Seu Pleiones of set parts by weight, Semen Plantaginis and system two crows are mixed, obtain hybrid medicine;
In described hybrid medicine, add water, and decoct 90-120 minute, obtain the first solidliquid mixture;
Add the Semen Coicis, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae of set parts by weight in described the first solidliquid mixture after, decoct for the second time, obtain the second solidliquid mixture;
Described the second solidliquid mixture is filtered, obtain being used for the treatment of the medicine of gout.
Optionally, described, the Pseudobulbus Cremastrae Seu Pleiones of set parts by weight, Semen Plantaginis and system two crows are mixed, obtain, in the step of hybrid medicine, specifically comprising: the described Semen Plantaginis of set parts by weight, with mixing with Pseudobulbus Cremastrae Seu Pleiones and system two crows of set parts by weight after gauze parcel, is obtained to hybrid medicine.
Optionally, after the described Semen Coicis that adds set parts by weight in described the first solidliquid mixture, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, decoct for the second time, obtain, in the step of the second solidliquid mixture, specifically comprising:
In described the first solidliquid mixture, add Semen Coicis, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae post-heating to the temperature of set parts by weight to be greater than 100 ℃, obtain decocting rear mixture; Mixture after described decoction is incubated to 15-25 minute at the temperature of 30-40 ℃, obtains the second solidliquid mixture.
This preparation method providing by the embodiment of the present invention can realize the preparation of the medicine that is used for the treatment of ventilation.
The specific embodiment
Below by specific embodiment, the present invention is described in further detail.
Embodiment mono-
A kind of medicine that is used for the treatment of gout is provided in an embodiment of the present invention, and according to parts by weight meter, its material component comprises:
Pseudobulbus Cremastrae Seu Pleiones 10-50 part, Semen Plantaginis 30-120 part, system two black 20-60 parts, Semen Coicis 50-150 part, Rhizoma Alismatis 30-120 part, Radix Clematidis 30-100 part, Semen Sinapis Albae 20-80 part, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae 20-100 part, Ramulus Cinnamomi 10-60 part, Radix Paeoniae Alba 50-200 part, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae 30-120 part.
The medicine that is used for the treatment of gout that the embodiment of the present invention provides, its material component is natural kind of medical herbs of set parts by weight, concrete, and Pseudobulbus cremastrae seu pleiones has the disappear effect of pain of heat-clearing and toxic substances removing, eliminating stagnation, wherein, containing multiple alkaloid, has good analgesic effect; Semen Plantaginis has the effect of relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, diuresis antiinflammatory; Make two crows and have wind-damp dispelling, the pain relieving of loose plug, be very suitable for treating arthralgia aggravated by cold, it,, containing multiple alkaloid, has good antiinflammatory, analgesia and local anesthetic action; Semen Coicis has the effect of promoting diuresis to eliminate damp pathogen, eliminating impediment.< < Sheng Nong's herbal classic > > records: the main muscular contracture of Semen Coicis is arrested twin, unable to flex and stretch the extremities, rheumatism numbness and the therapeutic method to keep the adverse QI flowing downwards, for a long time the clothes QI invigorating of making light of one's life by commiting suicide; Rhizoma Alismatis has the effect of promoting diuresis to eliminate damp pathogen, is the principal agent of diuretic; The Radix Clematidis benefaction twelve regular channels, has good dredging collateral effect; Semen Sinapis possesses promoting QI to circulate and dispersing the agglomeration of the pathogens, drives the effect of the outer expectorant of flesh side film; Radix Stephaniae Tetrandrae possesses the effect of wind-damp dispelling pain relieving, clearing away heat and promoting diuresis, and deficiency and excess is all available, for treating edema due to wind pathogen key medicine; Rhizoma Smilacis Glabrae possesses heat-clearing and toxic substances removing, the effect of dampness removing.The just > > of < < book on Chinese herbal medicine records its dampness removing and reduces phlegm and internal heat, and can enter network, searches and picks the damp and hot poison that accumulates; For Ramulus Cinnamomi, the < < book on Chinese herbal medicine > > that looks for the truth records it and dispels the wind loosely evil, is expelling pathogenic factors from muscles the first key medicine, and Ramulus Cinnamomi cuts down, for exterior symptoms in warming the meridian and promoting blood circulation all suitable; The Radix Paeoniae Alba possesses the effect of the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, relieving spasm to stop pain, the contracture pain of spasm of muscles and vessels; Radix Angelicae Sinensis possesses to enrich blood invigorates blood circulation, regulating menstruation, pain relieving, cures the wound and make each effect of returning to some extent of QI and blood; Radix Achyranthis Bidentatae possesses blood and dissolving stasis, invigorating the liver and kidney, bone and muscle strengthening, it is descending to ignite, and that relieving stranguria by diuresis, property are fallen is kind descending, draw the descending effect of all medicines; This medicine that is used for the treatment of gout that the embodiment of the present invention provides contains above-mentioned active princlple, and its strengthening body resistance and dispelling evil, radicallys reform, and energy fast reducing serum Uric Acid Concentration, recovers body metabolism.Because above-mentioned active drug component is all used pure natural Chinese herbal medicine, all medicines can share and alleviate GI irritation, also can well avoid the damage to liver and kidney.Therefore, the embodiment of the present invention provides this medicine that is used for the treatment of gout its when can realize treatment gout effect, also can not cause damage (or damaging minimum) to the gastrointestinal tract of human body, kidney and liver.
In addition, this medicine of the embodiment of the present invention, its active princlple all adopts pure natural Chinese herbal medicine, can effectively treat damp and hot, gout and metabolic arthritis card due to expectorant stasis blocking is stagnant.Righting evil removing original is refrigerant, can quick adjustment body, and reduce serum Uric Acid Concentration, recover organism metabolism, and to goat short treating period, pain relieving is rapid, and cure rate is high, and general 3 to 6 days i.e. effects are economical and practical.
In the present embodiment, concrete, in order to make medicine curative effect in the process for the treatment of ventilation of the embodiment of the present invention more remarkable, preferred, the component of each raw material can also form according to following proportioning:
Pseudobulbus Cremastrae Seu Pleiones 20-40 part, Semen Plantaginis 25-80 part, system two black 25-55 parts, Semen Coicis 60-100 part, Rhizoma Alismatis 40-100 part, Radix Clematidis 40-90 part, Semen Sinapis Albae 30-70 part, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae 40-80 part, Ramulus Cinnamomi 20-50 part, Radix Paeoniae Alba 60-180 part, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae 40-80 part.
In addition, on the basis of above-mentioned component, this medicine that is used for the treatment of ventilation of the present invention can also comprise following component:
Radix Angelicae Pubescentis 20-60 part, Olibanum 10-30 part, Radix Et Rhizoma Rhei 20-60 part, Caulis Akebiae 30-60 part, Radix Gentianae Macrophyllae 20-60 part, Rhizoma Atractylodis 20-60 part processed, Fructus Crataegi 10-50 part, Radix Glycyrrhizae 10-50 part, Fructus Chaenomelis 30-120 part, Caulis Trachelospermi 30-150 part, Radix Scutellariae 15-60 part, Herba speranskiae tuberculatae 20-100 part.
Now the effect of each component is listed below:
Radix Angelicae Pubescentis: wind-damp dispelling pain relieving, no matter newly all can apply for a long time, < < Decoction and Material Medica > > records, and two cold foot are wet actively not to be stopped, and non-this can not be controlled;
Olibanum: blood-activating and qi-promoting pain relieving, be good at stretching muscle;
Radix Et Rhizoma Rhei: eliminating fire and detoxication, removing heat from blood and promoting blood circulation, clearly rush down damp and hot;
Caulis Akebiae: clearing away heat and promoting diuresis, control damp and hot arthromyodynia;
Radix Gentianae Macrophyllae: for arthromyodynia pain, it is twin, for a long time new without asking that muscle arteries and veins is arrested, without inquiring about chills and fever all available it;
Rhizoma Atractylodis processed: < < Sheng Nong's herbal classic > > records that its main anemofrigid-damp arthralgia, dead flesh convulsion are twin, spleen invigorating, wind-damp dispelling;
Fructus Crataegi: promoting digestion and removing stagnation, blood circulation promoting and blood stasis dispelling, reduction hyperlipidemia, invigorate blood circulation that it is new not hinder;
Radix Glycyrrhizae: relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription;
Fructus Chaenomelis: the removing dampness of wind-damp dispelling relaxing muscles and tendons, no matter cold and heat all can be used as principal agent, is longer than medicine powder for relaxing muscle and controls maladministration;
Caulis Trachelospermi: < < key medicine divide agent > > record its " merit of trachelospermum jasminoide, specially in relaxing muscles and tendons and activating QI and blood in the collateral, the contracture of all patient's muscle arteries and veins is difficult for stretching bends person, clothes invariably obtain effect ";
Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis, enter blood system;
Herba speranskiae tuberculatae: can be used for controlling skin infection, eczema, scabies.
Select one or more as the component of medicine above-mentioned component, and then can make the active princlple of medicine more sufficient, make the drug effect of medicine more remarkable, can better be applied in the practice for the treatment of ventilation disease.
In the present embodiment, the medicine that is used for the treatment of gout is preferably decoction, and the manufacturing process of decoction is simple, with low cost.Certainly, according to the actual needs, the dosage form of medicine can be also pill, granule etc.
In addition, in medicine components, Radix Clematidis comprises the root of Wheeling Herba mesonae chinensis, and the effective ingredient containing due to the root of Wheeling Herba mesonae chinensis is horn of plenty more, and therefore, in the process of concrete operations, Radix Clematidis can be preferably the root of Wheeling Herba mesonae chinensis.
According to the content of above-described embodiment one, the present invention provides following specific embodiment with regard to the concrete proportioning of each component:
Embodiment bis-
According to parts by weight meter, the medicine that is used for the treatment of ventilation of this enforcement comprises: 10 parts of Pseudobulbus Cremastrae Seu Pleioness, 30 parts of Semen Plantaginiss, system two 20 parts of crows, 50 parts of Semen Coicis, 30 parts of Rhizoma Alismatis, 30 parts of Radix Clematidis, 20 parts of Semen Sinapis Albaes, 20 parts of Radix Stephaniae Tetrandrae, 20 parts of Rhizoma Smilacis Glabraes, 10 parts of Ramulus Cinnamomi, 50 parts of the Radix Paeoniae Albas, 40 parts of Radix Angelicae Sinensis, 30 parts of Radix Achyranthis Bidentataes.
Embodiment tri-
According to parts by weight meter, the medicine that is used for the treatment of ventilation of this enforcement comprises: 30 parts of Pseudobulbus Cremastrae Seu Pleioness, 70 parts of Semen Plantaginiss, system two 50 parts of crows, 100 parts of Semen Coicis, 70 parts of Rhizoma Alismatis, 60 parts of Radix Clematidis, 50 parts of Semen Sinapis Albaes, 40 parts of Radix Stephaniae Tetrandrae, 60 parts of Rhizoma Smilacis Glabraes, 35 parts of Ramulus Cinnamomi, 120 parts of the Radix Paeoniae Albas, 60 parts of Radix Angelicae Sinensis, 70 parts of Radix Achyranthis Bidentataes.
Embodiment tetra-
According to parts by weight meter, the medicine that is used for the treatment of ventilation of this enforcement comprises: 50 parts of Pseudobulbus Cremastrae Seu Pleioness, 120 parts of Semen Plantaginiss, system two 60 parts of crows, 150 parts of Semen Coicis, 120 parts of Rhizoma Alismatis, 100 parts of Radix Clematidis, 80 parts of Semen Sinapis Albaes, 60 parts of Radix Stephaniae Tetrandrae, 100 parts of Rhizoma Smilacis Glabraes, 60 parts of Ramulus Cinnamomi, 200 parts of the Radix Paeoniae Albas, 80 parts of Radix Angelicae Sinensis, 120 parts of Radix Achyranthis Bidentataes.
Embodiment five
According to parts by weight meter, the medicine that is used for the treatment of ventilation of this enforcement comprises: 10 parts of Pseudobulbus Cremastrae Seu Pleioness, 30 parts of Semen Plantaginiss, system two 20 parts of crows, 50 parts of Semen Coicis, 30 parts of Rhizoma Alismatis, 30 parts of Radix Clematidis, 20 parts of Semen Sinapis Albaes, 20 parts of Radix Stephaniae Tetrandrae, 20 parts of Rhizoma Smilacis Glabraes, 10 parts of Ramulus Cinnamomi, 50 parts of the Radix Paeoniae Albas, 40 parts of Radix Angelicae Sinensis, 30 parts of Radix Achyranthis Bidentataes, 20 parts of Radix Angelicae Pubescentiss, 10 parts of Olibanums, 20 parts of Radix Et Rhizoma Rhei, 30 parts of Caulis Akebiaes, 20 parts of Radix Gentianae Macrophyllae, 20 parts of Rhizoma Atractylodis processed, 10 parts of Fructus Crataegis, 10 parts, Radix Glycyrrhizae, 30 parts of Fructus Chaenomeliss, 30 parts of Caulis Trachelospermis, 15 parts of Radix Scutellariaes, 20 parts of Herba speranskiae tuberculataes.
Embodiment six
According to parts by weight meter, the medicine that is used for the treatment of ventilation of this enforcement comprises: 30 parts of Pseudobulbus Cremastrae Seu Pleioness, 70 parts of Semen Plantaginiss, system two 50 parts of crows, 100 parts of Semen Coicis, 70 parts of Rhizoma Alismatis, 60 parts of Radix Clematidis, 50 parts of Semen Sinapis Albaes, 40 parts of Radix Stephaniae Tetrandrae, 60 parts of Rhizoma Smilacis Glabraes, 35 parts of Ramulus Cinnamomi, 120 parts of the Radix Paeoniae Albas, 60 parts of Radix Angelicae Sinensis, 70 parts of Radix Achyranthis Bidentataes, 40 parts of Radix Angelicae Pubescentiss, 20 parts of Olibanums, 40 parts of Radix Et Rhizoma Rhei, 45 parts of Caulis Akebiaes, 40 parts of Radix Gentianae Macrophyllae, 40 parts of Rhizoma Atractylodis processed, 30 parts of Fructus Crataegis, 30 parts, Radix Glycyrrhizae, 75 parts of Fructus Chaenomeliss, 90 parts of Caulis Trachelospermis, 40 parts of Radix Scutellariaes, 60 parts of Herba speranskiae tuberculataes.
Embodiment seven
According to parts by weight meter, the medicine that is used for the treatment of ventilation of this enforcement comprises: 50 parts of Pseudobulbus Cremastrae Seu Pleioness, 120 parts of Semen Plantaginiss, system two 60 parts of crows, 150 parts of Semen Coicis, 120 parts of Rhizoma Alismatis, 100 parts of Radix Clematidis, 80 parts of Semen Sinapis Albaes, 60 parts of Radix Stephaniae Tetrandrae, 100 parts of Rhizoma Smilacis Glabraes, 60 parts of Ramulus Cinnamomi, 200 parts of the Radix Paeoniae Albas, 80 parts of Radix Angelicae Sinensis, 120 parts of Radix Achyranthis Bidentataes, 60 parts of Radix Angelicae Pubescentiss, 30 parts of Olibanums, 60 parts of Radix Et Rhizoma Rhei, 60 parts of Caulis Akebiaes, 60 parts of Radix Gentianae Macrophyllae, 60 parts of Rhizoma Atractylodis processed, 50 parts of Fructus Crataegis, 50 parts, Radix Glycyrrhizae, 120 parts of Fructus Chaenomeliss, 150 parts of Caulis Trachelospermis, 60 parts of Radix Scutellariaes, 100 parts of Herba speranskiae tuberculataes.
In order to make the medicine that is used for the treatment of gout of the embodiment of the present invention one, better applied, more effectively be applied in patient's treatment, the present invention is also provided for treating the preparation method of the medicine of gout on the basis of above-described embodiment one, is now described in detail and explains:
The preparation method that the embodiment of the present invention provides comprises the following steps:
1, the Pseudobulbus Cremastrae Seu Pleiones of set parts by weight, Semen Plantaginis and system two crows are mixed, obtain hybrid medicine;
2, in hybrid medicine, add water, and decoct 90-120 minute, obtain the first solidliquid mixture;
In above-mentioned steps, because the quality of Pseudobulbus Cremastrae Seu Pleiones, Semen Plantaginis and system two crows is harder, therefore, the time of its decoction is compared with other components should be more longer, so just can make wherein contained effective ingredient discharge as much as possible, and then increase the curative effect (and also can make not numb mouthful of decoction liquor) of medicine.
In addition, in above-mentioned step, because Semen Plantaginis is the granular medicament disperseing, therefore, preferred, in the process of operation, take to mix with Pseudobulbus Cremastrae Seu Pleiones and system two crows of set parts by weight after the Semen Plantaginis of set parts by weight is wrapped up with gauze, obtain hybrid medicine.And then hybrid medicine is decocted to 90-120 minute, and then obtain the first solidliquid mixture.
3, decoct for the second time add the Semen Coicis, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae of set parts by weight in the first solidliquid mixture after, obtain the second solidliquid mixture;
In this step, after obtaining the first solidliquid mixture, other components are added to wherein, and then decoct for the second time, and then obtain the second solidliquid mixture; In this operation, for the active drug composition of each component is separated out as much as possible, preferred, operate in the following manner:
In the first solidliquid mixture, add Semen Coicis, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae post-heating to the temperature of set parts by weight to be greater than 100 ℃, obtain decocting rear mixture;
Mixture after decocting is incubated to 15-25 minute at the temperature of 30-40 ℃, obtains the second solidliquid mixture.
First by adding, have Semen Coicis, the first solidliquid mixture of the component such as Rhizoma Alismatis is heated to its temperature and is greater than 100 ℃, is about to that it is boiled, obtains decocting rear mixture.Now, be incubated 15-25 minute using instead at the temperature of 30-40 ℃,, by the mode of slow fire heating, the effective ingredient of each medicine slowly separated out, and then obtain the second solidliquid mixture.
When it is pointed out that add other component in the first solidliquid mixture, because Semen Sinapis Albae exists with granular form equally, therefore, in order to prevent that it is scattered to decoction liquor in the process decocting, preferred, Semen Sinapis Albae need to be wrapped up with gauze.
4, the second solidliquid mixture is filtered, obtains being used for the treatment of the medicine of gout:
By above-mentioned operation, the second solidliquid mixture is filtered, can obtain liquid medicine, according to doctor's advice, take.
In addition, in the process that the second solidliquid mixture is filtered, can obtain solid residue, solid residue can further be used as fertilizers for potted flowers, or dries rear pulverizing as fuel etc.
Be below the Drug therapy patient's who is used for the treatment of gout that makes by above-described embodiment concrete case (cited case is comparatively typical case, and the case for the treatment of is not limit at following lifted example):
Case 1
Patient A, at 45 years old age, in the process of seafood, simultaneously drinks beer causes its left foot first toe joint to swell and ache on the feed, takes medicine that the embodiment of the present invention provides after a couple of days, and pain obviously alleviates.
Case 2
Patient B, 52 years old age, without obvious inducement, there is right sufficient thumb joint congestion and swelling pain, take colchicine 1mg every day three times, diclofenac 50mg, every twice-daily.After above-mentioned treatment, slightly take a favorable turn, but can not tolerate the untoward reaction such as nausea,vomiting,diarrhea that said medicine is brought, then stop treatment, change and take medicine three pairs that the embodiment of the present invention provides, obvious reducing swelling and alleviating pain, and have no adverse reaction, the continuous Zhou Eryu that takes.
Case 3
Patient C, right sufficient thumb joint swelling, pain is persistence acupuncture sample, fix and do not move, night, pain increased the weight of, and alleviate daytime, without radiating pain, without fear of cold heating, without the large joint migration of extremity pain, without the symmetry shuttle type swelling of the little joint of extremity, take the medicine that the embodiment of the present invention provides, twice, two day every day a pair, take medicine after three days, obviously the continuous Zhou Eryu that takes of pain relieving.
To sum up, this medicine that is used for the treatment of gout provided by the invention, its strengthening body resistance and dispelling evil, radicallys reform, and energy fast reducing serum Uric Acid Concentration, recovers body metabolism.Use pure natural Chinese herbal medicine as the active princlple of medicine, all medicines share, and alleviate GI irritation, avoid damaging liver, renal function.Can long-term taking, and avoid repeatedly showing effect.It is damp and hot that the medicine that the embodiment of the present invention provides can be imitated treatment, gout and metabolic arthritis card due to expectorant stasis blocking is stagnant.Scalable body fast reducing serum Uric Acid Concentration, recovers organism metabolism, to goat short treating period.Pain relieving is rapid, curative effect good.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (9)
1. a medicine that is used for the treatment of gout, is characterized in that, according to parts by weight meter, its material component comprises:
Pseudobulbus Cremastrae Seu Pleiones 10-50 part, Semen Plantaginis 30-120 part, system two black 20-60 parts, Semen Coicis 50-150 part, Rhizoma Alismatis 30-120 part, Radix Clematidis 30-100 part, Semen Sinapis Albae 20-80 part, Radix Stephaniae Tetrandrae 20-60 part, Rhizoma Smilacis Glabrae 20-100 part, Ramulus Cinnamomi 10-60 part, Radix Paeoniae Alba 50-200 part, Radix Angelicae Sinensis 40-80 part, Radix Achyranthis Bidentatae 30-120 part.
2. the medicine that is used for the treatment of gout according to claim 1, is characterized in that, according to parts by weight meter, its material component comprises:
Pseudobulbus Cremastrae Seu Pleiones 20-40 part, Semen Plantaginis 25-80 part, system two black 25-55 parts, Semen Coicis 60-100 part, Rhizoma Alismatis 40-100 part, Radix Clematidis 40-90 part, Semen Sinapis Albae 30-70 part, Radix Stephaniae Tetrandrae 20-60 part, Rhizoma Smilacis Glabrae 40-80 part, Ramulus Cinnamomi 20-50 part, Radix Paeoniae Alba 60-180 part, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae 40-80 part.
3. the medicine that is used for the treatment of gout according to claim 1, is characterized in that, according to parts by weight meter, its material component also comprises:
Radix Angelicae Pubescentis 20-60 part, Olibanum 10-30 part, Radix Et Rhizoma Rhei 20-60 part, Caulis Akebiae 30-60 part.
4. the medicine that is used for the treatment of gout according to claim 3, is characterized in that, according to parts by weight meter, its material component also comprises:
Radix Gentianae Macrophyllae 20-60 part, Rhizoma Atractylodis 20-60 part processed, Fructus Crataegi 10-50 part, Radix Glycyrrhizae 10-50 part, Fructus Chaenomelis 30-120 part, Caulis Trachelospermi 30-150 part, Radix Scutellariae 15-60, Herba speranskiae tuberculatae 20-100 part.
5. according to the medicine that is used for the treatment of gout described in claim 1-4 any one, it is characterized in that, described Radix Clematidis comprises the root of Wheeling Herba mesonae chinensis.
6. the medicine that is used for the treatment of gout according to claim 5, is characterized in that, described in be used for the treatment of the medicine of gout dosage form be decoction.
7. a preparation method that is used for the treatment of the medicine of gout according to claim 1, is characterized in that, comprises the following steps:
The Pseudobulbus Cremastrae Seu Pleiones of set parts by weight, Semen Plantaginis and system two crows are mixed, obtain hybrid medicine;
In described hybrid medicine, add water, and decoct 90-120 minute, obtain the first solidliquid mixture;
Add the Semen Coicis, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae of set parts by weight in described the first solidliquid mixture after, decoct for the second time, obtain the second solidliquid mixture;
Described the second solidliquid mixture is filtered, obtain being used for the treatment of the medicine of gout.
8. preparation method according to claim 7, is characterized in that, described, the Pseudobulbus Cremastrae Seu Pleiones of set parts by weight, Semen Plantaginis and system two crows is mixed, and obtains, in the step of hybrid medicine, specifically comprising:
The described Semen Plantaginis of set parts by weight, with mixing with Pseudobulbus Cremastrae Seu Pleiones and system two crows of set parts by weight after gauze parcel, is obtained to hybrid medicine.
9. preparation method according to claim 8, it is characterized in that, after the described Semen Coicis that adds set parts by weight in described the first solidliquid mixture, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, decoct for the second time, obtain, in the step of the second solidliquid mixture, specifically comprising:
In described the first solidliquid mixture, add Semen Coicis, Rhizoma Alismatis, Radix Clematidis, Semen Sinapis Albae, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Achyranthis Bidentatae post-heating of set parts by weight higher than 100 ℃, to obtain decocting rear mixture to temperature;
Mixture after described decoction is incubated to 15-25 minute at 30-40 ℃, obtains the second solidliquid mixture.
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| CN105749072A (en) * | 2016-03-31 | 2016-07-13 | 深圳市老年医学研究所 | Chinese medicine composition for preventing and treating hyperuricemia and hyperlipemia and preparation method thereof |
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| CN104162063A (en) * | 2014-09-03 | 2014-11-26 | 广州诺金制药有限公司 | Traditional Chinese medicine compound preparation for treating hyperuricemia and production method thereof |
| CN104162063B (en) * | 2014-09-03 | 2016-06-01 | 广州诺金制药有限公司 | A kind of compound Chinese medicinal preparation and its preparation method treating hyperuricemia |
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| CN105749072B (en) * | 2016-03-31 | 2020-05-22 | 深圳市老年医学研究所 | Chinese medicinal composition for preventing and treating hyperuricemia and hyperlipemia and preparation method thereof |
| CN106334130A (en) * | 2016-11-07 | 2017-01-18 | 陈中元 | Medicine for treating gout |
| CN107669991A (en) * | 2017-11-24 | 2018-02-09 | 成都中医药大学附属医院 | A kind of pharmaceutical composition for reducing serum uric acid level and preparation method thereof |
| CN107669991B (en) * | 2017-11-24 | 2020-11-06 | 成都中医药大学附属医院 | Pharmaceutical composition for reducing blood uric acid level and preparation method thereof |
| CN108096527A (en) * | 2017-12-29 | 2018-06-01 | 南宁市共健源健康科技有限公司 | Treat lozenge of gout and preparation method thereof |
| CN110478452A (en) * | 2019-10-16 | 2019-11-22 | 江西中医药大学附属医院 | A kind of Chinese medicine composition and preparation method thereof for treating gout |
| CN114788853A (en) * | 2021-01-25 | 2022-07-26 | 江西省人民医院 | Traditional Chinese medicine suitable for treating arthralgia |
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