CN103520541B - Dressing umbilicus granule for treating postnatal neurosis intestinal obstruction and preparation method thereof - Google Patents
Dressing umbilicus granule for treating postnatal neurosis intestinal obstruction and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a dressing umbilicus granule for treating postnatal neurosis intestinal obstruction and a preparation method thereof in order to solve the problem of treatment of postnatal neurosis intestinal obstruction. The preparation method comprises the following steps: (1) distilling mulberries, Chinese alyxia herb and bark or root of littleflower stringbush with water steam, extracting volatile oil for standby use and reserving dregs; (2) grinding amblystegium serpens and toasted rice-grain sprout into fine powder for standby use; (3) uniformly mixing aspongopus, sargassumthunbergii(Mert.)O.Kuntze, scandent schefflera stem and leaf, allium victorialis, radix ranunculi ternate, Chinese starjasmine stem and cassia twig with the dregs obtained in the step 1 uniformly, carrying out ethanol extraction twice, merging the two ethanol extracts, filtering the ethanol extracts, recovering ethanol and carrying out reduced pressure concentrating to obtain an extract; and (4) adding the fine powder obtained in the step 2 to the extract obtained in the step 3 and mixing the fine powder with the extract uniformly, drying the mixture at 60 DEG C, grinding the mixture into fine powder, adding polysorbate-80 to prepare a granule, drying the granule, shaping the granule, spraying the volatile oil obtained in the step 1, mixing the granule with the volatile oil uniformly and filling the mixture into a dressing umbilicus, thus obtaining the dressing umbilicus granule. Clinical experiments prove that the dressing umbilicus granule for treating postnatal neurosis intestinal obstruction has the characteristics of good curative effects and higher safety and is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of deposited umbilicus granule for the treatment of Cherchevski's in puerperal and preparation method thereof.
Background technology
Cherchevski's (Neurosis Intestinal Obstruction, NIO) is divided into paralytic Cherchevski's and spastic Cherchevski's according to symptom, and its pathogenic factor is that abdominal cavity stimulates more.No matter be spontaneous labor or cesarean, be all a kind of huge change of state for abdominal cavity, makes it the factor that starts becoming NIO, then intestinal limited fine-motoric occurs.
Puerperal, NIO was different from common paralytic intestinal obstruction after operation.One is: after this pathological changes can occur in any childbirth options, and clearly relevant to patient's body constitution, and this patient that has its source in of its generation is responsive to the height of abdominal cavity environmental change.It two is: puerperal, NIO showed as paralysis and spasm alternately outbreak, and symptom is unstable, and paralytic intestinal obstruction after operation is then benumbed to cause for intestinal and is short of power.
The same paralytic intestinal obstruction after operation of process after this pathological changes appearance at present, namely uses the medicine promoting enterokinesia.But because the two pathologic basis is different, some cases is intestinal cramps state, uses the medicine of short enterokinesia to increase the weight of symptom on the contrary.And the NIO occurred after spontaneous labor not yet has appropriate therapeutic scheme.
Summary of the invention
Technical assignment of the present invention is for above the deficiencies in the prior art, provides a kind of curative effect certainly and deposited umbilicus granule of the little treatment Cherchevski's in puerperal of side effect and preparation method thereof.
The technical scheme that the present invention solves its technical problem is: a kind of pharmaceutical composition for the treatment of Cherchevski's in puerperal, it is characterized in that being prepared from by the crude drug of following weight proportion: Aspongopus 10 ~ 30 parts, Herba Alyxiae Sinensis 6 ~ 12 parts, alizarin 3 ~ 10 parts of sea, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6 ~ 12 parts, Cortex Seu Radix Wikstroemiae Micranthae 3 ~ 10 parts, Bulbus Allii Victorialis 6 ~ 12 parts, Fructus Mori 6 ~ 12 parts, Radix Ranunculi Ternati 6 ~ 12 parts, Caulis Trachelospermi 6 ~ 12 parts, Folium Salicis Babylonicae moss 1 ~ 5 part, Ramulus Cinnamomi 3 ~ 10 parts, Fructus Setariae Germinatus (parched to brown) 10 ~ 25 parts.
Chinese medicine of the present invention can be prepared from by following method:
(1) Fructus Mori, Herba Alyxiae Sinensis, Cortex Seu Radix Wikstroemiae Micranthae coarse powder are extracted volatile oil 6 hours with vapor distillation after soaking 4 hours separately, and mixing for standby use after collecting, medicinal residues are for subsequent use;
(2) Folium Salicis Babylonicae moss, Fructus Setariae Germinatus (parched to brown) are pulverized 150 mesh sieves, and become fine powder for subsequent use;
(3) by gained medicinal residues mixing in Aspongopus, Hai Qian, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Bulbus Allii Victorialis, Radix Ranunculi Ternati, Caulis Trachelospermi, Ramulus Cinnamomi and step 1 with 5 times amount 80% ethanol extraction 2 times, each 2 hours, merge twice ethanol extract, filter, reclaiming relative density when ethanol concentrating under reduced pressure become 60 DEG C is the extractum of 1.25 ~ 1.30;
(4) gained fine powder in step 2 is added gained extractum mixing in step 3,60 DEG C of oven dry, are ground into fine powder, add Tween-80 and make granule, and dry, granulate, sprays into gained volatile oil in step 1, and mixing, subpackage, to obtain final product.
Wherein said: Aspongopus is the dry body of Pentatomidae Insects Aspongopus Aspongopus chinensis Dallas.Nature and flavor are salty, temperature.Return liver,spleen,kidney warp.Merit can regulating QI to relieve pain, and warming middle-JIAO is supporing yang.
Herba Alyxiae Sinensis is herb and the root of apocynaceae plant chain pearl rattan.Toil, flat.Enter lung, liver, spleen three warp.Merit can expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral.
Hai Qian is Sargassaceae plant Alga Sgrgassi Enerves Sargassum enerve C.Ag., Sargassum henslowianum Sargassum henslowianum C.Ag., sargassum thunbergii Sargassum thunbergii(Mert.) O.Kuntze or Sargassum phyllocystum Tseng et Lu,Sargassum horneri (Turn.) C. Ag. (Fucus horneri (Turn.)C.Ag.,Spongocarpus horneri Kutz.) argassum horneri(Turn.) frond of C. Ag.Nature and flavor are salty; Cold.Return liver; Stomach; Kidney channel.Merit can hard masses softening and resolving; Removing heat-phlegm.
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), is Araliaceae Schefflera plant schefflera arboricola Scheffleva arboricola Hayata and Schefflera venulosa (Wight et Arn.) Harms S.venulosa (Wight et Arn.) Harms, is used as medicine with stem and leaf.Nature and flavor are bitter, sweet, temperature.Merit can pain relieving dissipating blood stasis, detumescence.
Cortex Seu Radix Wikstroemiae Micranthae is peel of stem and the root of Isolated From Thymelaeaceae Species little Huang structure Wikstroemia micrantha Hemsl..Sweet in the mouth; Property is put down.Return lung meridian.Merit can relieving cough and resolving phlegm; Heat reliving and toxin-eliminating.
Bulbus Allii Victorialis is the bulb of liliaceous plant Bulbus Allii Victorialis Allium victorialis L..Return lung meridian.Merit can dissipating blood stasis; Hemostasis; Removing toxic substances.
Fructus Mori is the dry fruit ear of moraceae plants Mulberry Morus alba L..Nature and flavor are sweet, sour, cold.GUIXIN, liver, kidney channel.Merit can be enriched blood YIN nourishing, promotes the production of body fluid and moisturizes.
Radix Ranunculi Ternati is the dried root of ranunculaceae plant Seynuns Kugelann Ranunculus ternatus Thunb..Nature and flavor sweet, acrid, warm.Return liver, lung meridian.Merit can eliminating stagnation, detumescence.
Caulis Trachelospermi is the dry zone leaf rattan of apocynaceae plant trachelospermum jasminoide Trachelospermum jasminoides (Lindl.) Lem..Hardship, is slightly cold.Return kidney, liver, kidney channel.Merit can dispelling wind and removing obstruction in the collateral, and removing heat from blood is subsided a swelling.
Folium Salicis Babylonicae moss, Folium Salicis Babylonicae moss is Amblystegiaceae Folium Salicis Babylonicae moss Amblystegium serpens(Hedw.) plant of B.S.G..Nature and flavor are puckery; Flat.Merit can astringing to arrest bleeding.
Ramulus Cinnamomi is the withe of canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor acrid, sweet, warm.Enter the heart, lung, urinary bladder channel.Merit can relieving the exterior syndrome by diaphoresis, promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI.
Fructus Setariae Germinatus (parched to brown), for the mature fruit of grass foxtail millet Setaria italica (L.) Beauv. is through drying of germinateing, fries to burnt brown according to frying method.Nature and flavor are sweet, temperature.Return spleen, stomach warp.Merit can help digestion and in, spleen benefiting and stimulating the appetite.
Compared with prior art, the present invention has following characteristics:
1, set forth one's views unique: start with from dredging collateral, to recover for the purpose of intestinal wall CO2 laser weld, avoid using purgatives medicine thing, although because purgatives medicine thing can solve abdominal distention for the moment, cause again new stimulation to intestinal wall, for a long time raw he become, protracted course of disease.And irritant laxative, for breastfeeding patient, mostly cause baby's times of defecation increase and stop suckling.
2, with Aspongopus, Herba Alyxiae Sinensis for monarch: inventor's clinical experience gained, Cherchevski's is a kind of reflexive performance after art midgut wall nerve is upset, and Aspongopus regulating QI to relieve pain, Herba Alyxiae Sinensis promoting blood circulation to remove obstruction in the collateral, can reduce this zest and reflect the untoward reaction brought to intestinal.Basic pharmacology test confirms: Partial small bowel obstruction rat model Aspongopus (20g crude drug/kg/d) and Herba Alyxiae Sinensis (10g crude drug/kg/d) mixing water decocting liquid gavage, can intestinal mucosa injury be reduced, to incomplete intestinal obstruction Intestinal Mucosa, there is protective effect; And the progradation of rat intestine wriggling is observed by charcoal end method, propelling rate (84.42 ± 13.24) % of Aspongopus, Herba Alyxiae Sinensis drug combination group is apparently higher than blank group of (59.33 ± 15.62) %.
3, using sea, alizarin hard masses softening and resolving, Cortex Seu Radix Wikstroemiae Micranthae digestion visible phlegm, Caulis Trachelospermi dispelling wind dredging collateral, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) pain relieving, Bulbus Allii Victorialis dissipating blood stasis, Radix Ranunculi Ternati mass dissipating and swelling eliminating assist monarch drug as ministerial drug: breath does not reach, of a specified duration then can block by accumulation of phlegm, so select Cortex Seu Radix Wikstroemiae Micranthae, the alizarin visible phlegm removed in intestinal venation in sea, Caulis Trachelospermi, Radix Ranunculi Ternati increase the ability of medicine walking venation.Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) can reduce intestinal high-tension state, alleviates intestinal cramps, but does not affect the intestinal peristalsis promoting rhythm and pace of moving things simultaneously, and this feature is that other analgesic drug products are unexistent, is particularly suitable for primary disease and uses.Bulbus Allii Victorialis has the advantages that dissipating blood stasis does not consume gas, is particularly suitable for simulataneous insufficiency and excessive use in puerperal.
4, use puerperal tonification medicine can affect gastrointestinal tract transporting in a large number, therefore prescription of the present invention only to be enriched blood YIN nourishing with Fructus Mori simply.
5, low dose of Folium Salicis Babylonicae moss, Ramulus Cinnamomi are corrigent, resist the anxiety that this prescription invasion by pathogenic cold medicine of a cold nature thing too much has consumption impairment of QI the moon, and the effect of its activating YANG and prormoting functioning of QI are also echoed with Aspongopus, contributes to row loose.And the use of Folium Salicis Babylonicae moss, be prevent the blood circulation promoting medicine in formula of the present invention from moving the raw wind of blood.
6, Fructus Setariae Germinatus (parched to brown) is sweet in flavor and warm in property, returns taste warp, get protect sun defend in meaning, and contained coking composition has astriction, has the meaning of receipts in loose.
7, the homogeneous medicine multiple-effect of institute's thing of getting it filled in side, contributes to reducing medicament categories and consumption, does not increase Liver and kidney burden.
8, medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, and each raw material dosage is for all to have good curative effect in following weight parts scope.
9, adopt deposited umbilicus dosage form, taking convenience, compliance is good, is convenient to accept.
Detailed description of the invention
Below in conjunction with practical situation, the specific embodiment of the present invention is elaborated.
Embodiment 1, crude drug weight proportion: Aspongopus 20 parts, Herba Alyxiae Sinensis 10 parts, alizarin 6 parts of sea, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10 parts, Cortex Seu Radix Wikstroemiae Micranthae 6 parts, Bulbus Allii Victorialis 10 parts, Fructus Mori 10 parts, Radix Ranunculi Ternati 10 parts, Caulis Trachelospermi 10 parts, Folium Salicis Babylonicae moss 2 parts, Ramulus Cinnamomi 6 parts, Fructus Setariae Germinatus (parched to brown) 20 parts.
The preparation method of embodiment 1 is: Aspongopus, Herba Alyxiae Sinensis, Hai Qian, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Cortex Seu Radix Wikstroemiae Micranthae, Bulbus Allii Victorialis, Fructus Mori, Radix Ranunculi Ternati, Caulis Trachelospermi, Folium Salicis Babylonicae moss, Ramulus Cinnamomi, Fructus Setariae Germinatus (parched to brown) mixing and water adding are decocted, filtrate is got after 30 minutes, medicinal residues add water continue decoction get filtrate after 20 minutes, twice filtrate merges, and is divided into two parts of morning and evenings to take.
Embodiment 2, crude drug weight proportion: Aspongopus 10 parts, Herba Alyxiae Sinensis 6 parts, alizarin 3 parts of sea, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6 parts, Cortex Seu Radix Wikstroemiae Micranthae 3 parts, Bulbus Allii Victorialis 6 parts, Fructus Mori 6 parts, Radix Ranunculi Ternati 6 parts, Caulis Trachelospermi 6 parts, Folium Salicis Babylonicae moss 1 part, Ramulus Cinnamomi 3 parts, Fructus Setariae Germinatus (parched to brown) 10 parts.
Embodiment 3, crude drug weight proportion: Aspongopus 20 parts, Herba Alyxiae Sinensis 10 parts, alizarin 6 parts of sea, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10 parts, Cortex Seu Radix Wikstroemiae Micranthae 6 parts, Bulbus Allii Victorialis 10 parts, Fructus Mori 10 parts, Radix Ranunculi Ternati 10 parts, Caulis Trachelospermi 10 parts, Folium Salicis Babylonicae moss 2 parts, Ramulus Cinnamomi 6 parts, Fructus Setariae Germinatus (parched to brown) 20 parts.
Embodiment 4, crude drug weight proportion: Aspongopus 30 parts, Herba Alyxiae Sinensis 12 parts, alizarin 10 parts of sea, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12 parts, Cortex Seu Radix Wikstroemiae Micranthae 10 parts, Bulbus Allii Victorialis 12 parts, Fructus Mori 12 parts, Radix Ranunculi Ternati 12 parts, Caulis Trachelospermi 12 parts, Folium Salicis Babylonicae moss 5 parts, Ramulus Cinnamomi 10 parts, Fructus Setariae Germinatus (parched to brown) 25 parts.
The Chinese medicine of embodiment 2 ~ 4 can be prepared from by following method:
(1) Fructus Mori, Herba Alyxiae Sinensis, Cortex Seu Radix Wikstroemiae Micranthae coarse powder are extracted volatile oil 6 hours with vapor distillation after soaking 4 hours separately, and mixing for standby use after collecting, medicinal residues are for subsequent use;
(2) Folium Salicis Babylonicae moss, Fructus Setariae Germinatus (parched to brown) are pulverized 150 mesh sieves, and become fine powder for subsequent use;
(3) by gained medicinal residues mixing in Aspongopus, Hai Qian, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Bulbus Allii Victorialis, Radix Ranunculi Ternati, Caulis Trachelospermi, Ramulus Cinnamomi and step 1 with 5 times amount 80% ethanol extraction 2 times, each 2 hours, merge twice ethanol extract, filter, reclaiming relative density when ethanol concentrating under reduced pressure become 60 DEG C is the extractum of 1.25 ~ 1.30;
(4) gained fine powder in step 2 is added gained extractum mixing in step 3,60 DEG C of oven dry, are ground into fine powder, add Tween-80 and make granule, and dry, granulate, sprays into gained volatile oil in step 1, and mixing, subpackage, to obtain final product.
The efficient combination of said medicine, coordinates mutually, effectively reach the object for the treatment of Cherchevski's in puerperal, and side effect is less.The above results is clinical data sufficient proof, and interrelated data is as follows.
1 object and method.
1.1 object.
1.1.1 case selection: case is selected from case 73 example occurring Cherchevski's in 7 days puerperal of in January, 2009 ~ 2013 year JIUYUE.Wherein spontaneous labor 24 example, cesarean section delivery 49 example.
1.1.2 Cherchevski's diagnostic criteria: (1) suffers from abdominal pain: paroxysmal abdominal pain; (2) vomit: high obstruction vomiting is comparatively frequent, it is less that low level blocks vomiting number of times, and vomitus is smelly with excrement; (3) abdominal distention: low level blocks full abdominal distention, often accompanies visible peristalsis visible intestinal peristalsis, high obstruction abdominal distention is not obvious; (4) aerofluxus and defecation stop; (5) sign: the intestinal tube of expansion has tenderness, rebound tenderness; Borborygmus is faint or disappear or gur gling; (6) x-ray diagnosis intestinal blocks important value.And get rid of mechanical intestinal obstruction.
1.1.3 be divided into three groups at random: matched group 25 example, decoction group 23 example, apply umbilicus group 25 example.Compare on age, Gestational period before three groups of patient treatments, no significant difference (P>0.05), has comparability.
1.2 method.
1.2.1 Therapeutic Method: matched group takes gastrointestinal decompression, fluid infusion, correction acid base imbalance, anti-infective therapy, decoction group adds with embodiment 1 gained decoction on matched group medication basis, 2 times/d; Apply umbilicus group on matched group medication basis, to add described embodiment 3 gained apply umbilicus agent vinegar and dress, 2 times/d, 5d altogether.
1.2.2 judge according to criterion of therapeutical effect ileac in " new Chinese medicine guideline of clinical investigations ".Recovery from illness: Clinical symptom and sign disappears, normal passage of gas by anus defecation, borborygmus recovers, and X-ray of abdomen intestinal tube inflatable dilatation disappears, and can pull out gastrointestinal decompression tube.Effective: Clinical symptom and sign obviously alleviates, borborygmus recovers substantially, and X-ray of abdomen intestinal tube inflatable dilatation obviously alleviates, and can close gastrointestinal decompression tube and observe.Effective: abdominal part distending pain alleviates to some extent, aerofluxus, defecation are not smooth, and abdominal part auscultation borborygmus is weak, and X-ray of abdomen intestinal tube inflatable dilatation alleviates, and still needs indwelling gastrointestinal decompression tube.Invalid: still without aerofluxus, defecation after medication 72 h, Clinical symptom and sign is without alleviation or increase the weight of.
1.2.3 statistical analysis: SPSS 13.0 carries out statistical analysis.Measurement data t checks, enumeration data χ
2inspection.
2 results.
2.1 3 groups of Clinical efficacy comparisons: see the following form.Result shows, and the cure rate of decoction group and deposited umbilicus group is apparently higher than matched group (decoction group P<0.01; Apply umbilicus group P<0.05); The total effective rate of decoction group and deposited umbilicus group is higher than matched group (P<0.05).
| Group | Number of cases | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Matched group | 25 | 2（8.00%） | 8（32.00%） | 8（32.00%） | 7（28.00%） | 72.00% |
| Decoction group | 23 | 12（52.17%） | 6（26.09%） | 4（17.39%） | 1（4.35%） | 95.65% |
| Apply umbilicus group | 25 | 8（32.00%） | 11（44.00%） | 5（20.00%） | 1（4.00%） | 96.00% |
2.2 3 groups of adverse reactions of patients incidence rates compare: three groups all do not occur obvious adverse reaction record.Decoction group has 4.35%(1/23) patient occur stop breast feeding situation because of baby's times of defecation > 6 times/day, matched group and deposited umbilicus group all do not occur.
3. conclusion.
This result of study shows, after using decoction of the present invention or deposited umbilicus, puerperal Cherchevski's patient cure rate, total effective rate is apparently higher than matched group, and there is not obvious adverse reaction record, illustrate that pharmaceutical composition prepared by the inventive method to have good effect, untoward reaction lighter advantage puerperal in treatment in Cherchevski's.
Claims (1)
1. treat the preparation method of the deposited umbilicus granule of Cherchevski's in puerperal for one kind, it is characterized in that, be prepared from by the crude drug of following weight proportion: Aspongopus 10 ~ 30 parts, Herba Alyxiae Sinensis 6 ~ 12 parts, alizarin 3 ~ 10 parts of sea, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6 ~ 12 parts, Cortex Seu Radix Wikstroemiae Micranthae 3 ~ 10 parts, Bulbus Allii Victorialis 6 ~ 12 parts, Fructus Mori 6 ~ 12 parts, Radix Ranunculi Ternati 6 ~ 12 parts, Caulis Trachelospermi 6 ~ 12 parts, Folium Salicis Babylonicae moss 1 ~ 5 part, Ramulus Cinnamomi 3 ~ 10 parts, Fructus Setariae Germinatus (parched to brown) 10 ~ 25 parts; Be made up of following steps:
(1) Fructus Mori, Herba Alyxiae Sinensis, Cortex Seu Radix Wikstroemiae Micranthae coarse powder are extracted volatile oil 6 hours with vapor distillation after soaking 4 hours separately, and mixing for standby use after collecting, medicinal residues are for subsequent use;
(2) Folium Salicis Babylonicae moss, Fructus Setariae Germinatus (parched to brown) are ground into fine powder, cross 150 mesh sieves, for subsequent use;
(3) by gained medicinal residues mixing in Aspongopus, Hai Qian, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Bulbus Allii Victorialis, Radix Ranunculi Ternati, Caulis Trachelospermi, Ramulus Cinnamomi and step (1) with 5 times amount 80% ethanol extraction 2 times, each 2 hours, merge twice ethanol extract, filter, reclaiming relative density when ethanol concentrating under reduced pressure become 60 DEG C is the extractum of 1.25 ~ 1.30;
(4) gained fine powder in step (2) is added gained extractum mixing in step (3), 60 DEG C of oven dry, are ground into fine powder, add Tween-80 and make granule, dry, granulate, spray into gained volatile oil in step (1), and mixing, subpackage, to obtain final product.
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| CN201310485572.9A CN103520541B (en) | 2013-10-17 | 2013-10-17 | Dressing umbilicus granule for treating postnatal neurosis intestinal obstruction and preparation method thereof |
| CN201510019969.8A CN104491560B (en) | 2013-10-17 | 2013-10-17 | A kind of oral drugs for treating postpartum Cherchevski's |
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| CN201310485572.9A CN103520541B (en) | 2013-10-17 | 2013-10-17 | Dressing umbilicus granule for treating postnatal neurosis intestinal obstruction and preparation method thereof |
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| CN201510019969.8A Division CN104491560B (en) | 2013-10-17 | 2013-10-17 | A kind of oral drugs for treating postpartum Cherchevski's |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101785850A (en) * | 2010-02-28 | 2010-07-28 | 泰一和浦（北京）中医药研究院有限公司 | Traditional combination and preparation method thereof for intestinal obstruction treatment |
| CN102335311A (en) * | 2011-10-20 | 2012-02-01 | 朱剑萍 | Decoction for treating intestinal obstruction, and application thereof |
| CN103041181A (en) * | 2013-01-25 | 2013-04-17 | 汪霞 | Umbilical compressed nursing cream for treating secondary bladder neck contracture |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101785850A (en) * | 2010-02-28 | 2010-07-28 | 泰一和浦（北京）中医药研究院有限公司 | Traditional combination and preparation method thereof for intestinal obstruction treatment |
| CN102335311A (en) * | 2011-10-20 | 2012-02-01 | 朱剑萍 | Decoction for treating intestinal obstruction, and application thereof |
| CN103041181A (en) * | 2013-01-25 | 2013-04-17 | 汪霞 | Umbilical compressed nursing cream for treating secondary bladder neck contracture |
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