CN103055096B - Application for freeze-dried Chinese yam in medicine preparation - Google Patents
Application for freeze-dried Chinese yam in medicine preparation Download PDFInfo
- Publication number
- CN103055096B CN103055096B CN201310008646.XA CN201310008646A CN103055096B CN 103055096 B CN103055096 B CN 103055096B CN 201310008646 A CN201310008646 A CN 201310008646A CN 103055096 B CN103055096 B CN 103055096B
- Authority
- CN
- China
- Prior art keywords
- rhizoma dioscoreae
- lyophilizing
- extract
- temperature
- hours
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 240000001811 Dioscorea oppositifolia Species 0.000 title abstract description 7
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 title abstract description 7
- 235000002722 Dioscorea batatas Nutrition 0.000 title abstract 5
- 235000006536 Dioscorea esculenta Nutrition 0.000 title abstract 5
- 210000000952 spleen Anatomy 0.000 claims abstract description 13
- 210000002784 stomach Anatomy 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000008187 granular material Substances 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 238000000859 sublimation Methods 0.000 claims description 10
- 230000008022 sublimation Effects 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 6
- 238000013459 approach Methods 0.000 claims description 4
- 238000003809 water extraction Methods 0.000 claims description 4
- 241000208340 Araliaceae Species 0.000 claims description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 2
- 229920002472 Starch Polymers 0.000 claims description 2
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 2
- 235000008434 ginseng Nutrition 0.000 claims description 2
- 235000020710 ginseng extract Nutrition 0.000 claims description 2
- 239000002002 slurry Substances 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 235000019698 starch Nutrition 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims description 2
- 230000003014 reinforcing effect Effects 0.000 abstract description 11
- 210000003734 kidney Anatomy 0.000 abstract description 10
- 210000004072 lung Anatomy 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 7
- 230000001737 promoting effect Effects 0.000 abstract 2
- 210000003296 saliva Anatomy 0.000 abstract 2
- 230000028327 secretion Effects 0.000 abstract 2
- 210000001124 body fluid Anatomy 0.000 description 8
- 239000010839 body fluid Substances 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 8
- 239000002994 raw material Substances 0.000 description 8
- 239000006187 pill Substances 0.000 description 7
- 241000234272 Dioscoreaceae Species 0.000 description 5
- 239000002775 capsule Substances 0.000 description 5
- 150000004676 glycans Chemical class 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- 230000003203 everyday effect Effects 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
- 239000003826 tablet Substances 0.000 description 4
- 230000000259 anti-tumor effect Effects 0.000 description 3
- 230000003078 antioxidant effect Effects 0.000 description 3
- 206010012601 diabetes mellitus Diseases 0.000 description 3
- 235000004879 dioscorea Nutrition 0.000 description 3
- 238000004821 distillation Methods 0.000 description 3
- 238000007710 freezing Methods 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 238000011068 loading method Methods 0.000 description 3
- 238000007711 solidification Methods 0.000 description 3
- 230000008023 solidification Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 229920001353 Dextrin Polymers 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- 241000234273 Dioscorea Species 0.000 description 2
- 235000005903 Dioscorea Nutrition 0.000 description 2
- 235000000504 Dioscorea villosa Nutrition 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 208000022531 anorexia Diseases 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 229930182490 saponin Natural products 0.000 description 2
- 150000007949 saponins Chemical class 0.000 description 2
- 235000017709 saponins Nutrition 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 229930183633 Batatasin Natural products 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 1
- 206010010144 Completed suicide Diseases 0.000 description 1
- 244000281702 Dioscorea villosa Species 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 206010018473 Glycosuria Diseases 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 229960003638 dopamine Drugs 0.000 description 1
- -1 dry Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
? | Water extraction content (%) | Polyoses content (%) |
Rhizoma Dioscoreae decoction pieces | 17.26 | 5.82 |
Lyophilizing Rhizoma Dioscoreae | 36.17 | 26.36 |
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310008646.XA CN103055096B (en) | 2013-01-10 | 2013-01-10 | Application for freeze-dried Chinese yam in medicine preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310008646.XA CN103055096B (en) | 2013-01-10 | 2013-01-10 | Application for freeze-dried Chinese yam in medicine preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103055096A CN103055096A (en) | 2013-04-24 |
CN103055096B true CN103055096B (en) | 2014-11-26 |
Family
ID=48098191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310008646.XA Active CN103055096B (en) | 2013-01-10 | 2013-01-10 | Application for freeze-dried Chinese yam in medicine preparation |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103055096B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103478637A (en) * | 2013-08-23 | 2014-01-01 | 广西大学 | Method for preparing dried Chinese yam through vacuum freeze drying |
CN103599322B (en) * | 2013-11-07 | 2016-08-17 | 培力(南宁)药业有限公司 | A kind of Yam dispensing granule preparation method |
CN103652929B (en) * | 2013-12-31 | 2015-06-17 | 陈慧婷 | Sorghum and semen coicis dispersible tablet and preparation method thereof |
CN104154713A (en) * | 2014-08-25 | 2014-11-19 | 济南康众医药科技开发有限公司 | Lamiophlomis freeze-drying method |
CN104165498A (en) * | 2014-08-25 | 2014-11-26 | 济南康众医药科技开发有限公司 | Scutellaria baicalensis freeze-drying method |
CN107439869A (en) * | 2017-08-02 | 2017-12-08 | 广西壮族自治区药用植物园 | The preparation method of liquid fresh yam drink |
CN108782909A (en) * | 2018-09-14 | 2018-11-13 | 铜川药王医都科技有限公司 | A kind of summer health care tea |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1228944A (en) * | 1999-03-02 | 1999-09-22 | 董起年 | High-efficient production method for freeze and vacuum dried Chinese yam powder |
CN1927001A (en) * | 2006-09-30 | 2007-03-14 | 河南省农科院农副产品加工研究所 | Chinese yam vacuum microwave freeze-drying technology |
-
2013
- 2013-01-10 CN CN201310008646.XA patent/CN103055096B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1228944A (en) * | 1999-03-02 | 1999-09-22 | 董起年 | High-efficient production method for freeze and vacuum dried Chinese yam powder |
CN1927001A (en) * | 2006-09-30 | 2007-03-14 | 河南省农科院农副产品加工研究所 | Chinese yam vacuum microwave freeze-drying technology |
Non-Patent Citations (6)
Title |
---|
孙慧等.提高冻干山药片品质的工艺优化.《食品科学》.2011,第32卷(第10期),第92页左栏第1行-右栏第5行,第93页左栏第8-13行,右栏第8-12行,第96页左栏第8-15行. * |
山药的开发利用;聂凌鸿等;《中国野生植物资源》;20021231;第21卷(第5期);摘要,第17页右栏第18行-第18页右栏第4行 * |
山药真空冷冻干燥的实验研究;徐成海等;《真空科学与技术》;19961130;第16卷(第6期);449-452 * |
徐成海等.山药真空冷冻干燥的实验研究.《真空科学与技术》.1996,第16卷(第6期),449-452. * |
提高冻干山药片品质的工艺优化;孙慧等;《食品科学》;20111231;第32卷(第10期);第92页左栏第1行-右栏第5行,第93页左栏第8-13行,右栏第8-12行,第96页左栏第8-15行 * |
聂凌鸿等.山药的开发利用.《中国野生植物资源》.2002,第21卷(第5期),摘要,第17页右栏第18行-第18页右栏第4行. * |
Also Published As
Publication number | Publication date |
---|---|
CN103055096A (en) | 2013-04-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103055096B (en) | Application for freeze-dried Chinese yam in medicine preparation | |
KR101455173B1 (en) | Noodles and noodle preparation method using wild ginseng | |
CN101385827B (en) | Sea cucumber health paste and production method thereof | |
CN104288227A (en) | Novel drying method of fresh traditional Chinese medicine materials and application of dried traditional Chinese medicine materials | |
CN104771563B (en) | The compound Chinese medicinal preparation and preparation method of a kind of kidney tonifying | |
CN101744340B (en) | Preparation method of ginger and jujube granule | |
CN104306655A (en) | Vegetable preparation for reducing blood pressure, blood glucose and blood fat and preparation method thereof | |
CN101167882A (en) | Capsule for anti-oxidation | |
CN103055098A (en) | Freeze-dried yam for preventing and treating cancer | |
CN109620868A (en) | A kind of quickly effective green blood treasure pill and its preparation method and application | |
CN106343489A (en) | Processing method of black peanut with pure natural plant formula | |
CN106071411A (en) | A kind of mixed feed improving shrimp immunity vigor and preparation method thereof | |
CN103621898A (en) | Gingko root kudzuvine fine dried noodles and preparation method thereof | |
CN103610105A (en) | Manufacturing method of appetizing spiced egg | |
CN102670660A (en) | Processing method and application of aspongopus | |
CN103055097A (en) | Freeze-dried dioscorea opposita for treating diabetes mellitus | |
CN108887320A (en) | A kind of tawny daylily cake premixed powder and preparation method thereof | |
CN108143833A (en) | A kind of preparation method of licorice piece | |
KR101402600B1 (en) | Instant noodle manufacturing methods | |
CN105341890A (en) | Health food possessing bowel-relaxing effect and preparation method thereof | |
CN105475573A (en) | Preparation method of herba centellae substitutional tea | |
CN104757439A (en) | Fermented black bean-ginger powder and preparation method thereof | |
CN104286923A (en) | Braised goose mixed with sauce and preparation method thereof | |
CN108671008A (en) | Radix pseudostellariae is fresh to carry freeze-dried powder medicine materical crude slice | |
CN109567198A (en) | A kind of electuary and preparation method thereof improving insufficiency of vital energy and blood |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: JI'NAN SUNNYPHARMACY CO., LTD. Free format text: FORMER OWNER: JINAN KANGZHONG MEDICIN SCIENCE + TECHNOLOGY CO., LTD. Effective date: 20150508 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 250014 JINAN, SHANDONG PROVINCE TO: 250200 JINAN, SHANDONG PROVINCE |
|
TR01 | Transfer of patent right |
Effective date of registration: 20150508 Address after: 250200 Shandong Province, Zhangqiu City Industrial Economic Development Zone Mingshui Road Northwest Section Patentee after: JINAN SUNNYPHARMACY Co.,Ltd. Address before: Lixia District Hospital in Shandong province Ji'nan City Road 250014 No. 19 No. 4 West of Shandong Academy of Sciences Patentee before: JINAN KANGZHONG PHARMACEUTICAL TECHNOLOGY DEVELOPMENT Co.,Ltd. |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Application of freeze-dried yam in preparation of medicine Effective date of registration: 20221024 Granted publication date: 20141126 Pledgee: Shandong Tongsheng Financing Guarantee Co.,Ltd. Pledgor: JINAN SUNNYPHARMACY Co.,Ltd. Registration number: Y2022980019375 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20231123 Granted publication date: 20141126 Pledgee: Shandong Tongsheng Financing Guarantee Co.,Ltd. Pledgor: JINAN SUNNYPHARMACY Co.,Ltd. Registration number: Y2022980019375 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Application of freeze-dried yam in drug preparation Effective date of registration: 20231130 Granted publication date: 20141126 Pledgee: Shandong Tongsheng Financing Guarantee Co.,Ltd. Pledgor: JINAN SUNNYPHARMACY Co.,Ltd. Registration number: Y2023980068598 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |